J:Int. J. Pept. Protein Res.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6078 Pomc Positive_regulation of Localization of Penk 13 3 0.51 0 15.49
2 INT6079 Pomc Positive_regulation of Penk 9 2 0.43 0 9.46
3 INT21276 Binding of Oprd1 and Penk 9 2 0.54 1.14 8.28
4 INT6076 Negative_regulation of Pomc Positive_regulation of Penk 3 1 0.31 0 3.14
5 INT30345 Pomc Regulation of Localization of Penk 3 1 0.31 0 2.61
6 INT29996 Binding of Oprm1 and Penk 2 1 0.36 0.4 1.85
7 INT38624 Binding of Oprm1 and Insrr 2 1 0.01 0.24 1.31
8 INT29999 Binding of Ptger3 and Retnlb 1 1 0.00 0 0.71
9 INT32241 Pomc Negative_regulation of Pomc Positive_regulation of Penk 1 1 0.23 0 0.63
10 INT42847 Binding of Cpe and SLTM 1 1 0.00 0 0.38
11 INT7893 Binding of Oprm1 and Ccl21b 1 1 0.00 0.08 0.35
12 INT64382 Positive_regulation of Binding of YY1 and Tyr 1 1 0.11 0 0.21
13 INT64383 Binding of YY1 and Tyr 1 1 0.09 0 0.21
14 INT30709 Negative_regulation of Binding of Dbp and Gpi 1 1 0.00 0 0.16
15 INT30708 Binding of Dbp and Gpi 1 1 0.00 0 0.16

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT796 Gene_expression of Penk 3 1902 0.78 275.47 1057.59
2 INT292 Localization of Penk 5 876 0.81 88.44 669.14
3 INT467 Gene_expression of POMC 35 1048 0.78 332.8 394.16
4 INT1395 Negative_regulation of Penk 2 537 0.59 87.33 389.81
5 INT5660 Binding of Oprd1 4 477 0.48 71.86 342.06
6 INT5979 Gene_expression of Oprd1 2 428 0.78 75.64 320.32
7 INT4941 Positive_regulation of Oprd1 1 345 0.70 74.26 304.41
8 INT886 Gene_expression of Pomc 1 676 0.78 129.87 295.98
9 INT1396 Binding of Penk 1 355 0.48 22.79 269.65
10 INT6406 Binding of Oprm1 4 280 0.48 40.54 226.26
11 INT1308 Localization of Pomc 2 457 0.81 66.83 217.5
12 INT2651 Positive_regulation of Pomc 2 403 0.70 95.72 206.24
13 INT1652 Regulation of Pomc 2 387 0.62 61.01 186.51
14 INT12602 Negative_regulation of Oprm1 1 190 0.59 36.11 177.85
15 INT1429 Gene_expression of PDYN 9 308 0.78 61.33 175.65
16 INT5930 Positive_regulation of Oprm1 1 221 0.70 31.19 172.93
17 INT4937 Negative_regulation of Oprd1 2 224 0.59 44.51 171.11
18 INT6042 Binding of Oprm1 1 248 0.48 31.77 154.34
19 INT4658 Binding of OPRM1 1 188 0.48 25.96 136.24
20 INT695 Binding of POMC 9 304 0.48 56.66 126.85
21 INT6822 Gene_expression of Pdyn 3 215 0.78 35.99 125.76
22 INT2555 Positive_regulation of Localization of Penk 1 116 0.70 24.35 119.73
23 INT12569 Localization of Oprd1 1 94 0.81 23.81 104.56
24 INT6437 Binding of YY1 7 154 0.47 26.3 90.46
25 INT6656 Gene_expression of YY1 1 135 0.75 24.73 72.16
26 INT4153 Binding of Insrr 2 109 0.40 17.99 72.15
27 INT8962 Gene_expression of Cpe 1 110 0.71 39.67 71.67
28 INT462 Regulation of Pomc 1 157 0.62 41.67 67.27
29 INT5819 Regulation of Localization of Penk 1 64 0.62 6.69 57.68
30 INT1510 Binding of PDYN 5 94 0.48 4.68 56.44
31 INT1463 Binding of Pomc 1 129 0.48 15.89 56.27
32 INT6073 Negative_regulation of Localization of Penk 2 63 0.59 8.67 53.95
33 INT5704 Binding of Slc3a1 4 78 0.43 8.52 51.78
34 INT5136 Negative_regulation of PDYN 1 71 0.59 11.22 51.14
35 INT2323 Gene_expression of Trh 1 146 0.78 29.92 49.5
36 INT2262 Negative_regulation of Lhb 2 142 0.59 25.47 44.81
37 INT1163 Negative_regulation of Rbm39 1 64 0.29 16.8 34.74
38 INT2699 Binding of Cpe 1 40 0.48 7.07 33.64
39 INT21560 Positive_regulation of Binding of Oprm1 2 30 0.50 7.16 32.95
40 INT6717 Negative_regulation of YY1 1 45 0.57 15.35 27.8
41 INT5135 Negative_regulation of GNRH1 1 106 0.58 36.63 27.71
42 INT6382 Regulation of Binding of Oprd1 1 36 0.61 7 26.48
43 INT2261 Gene_expression of Lhb 3 121 0.77 42.78 26.04
44 INT6934 Binding of OPRD1 2 51 0.48 7.72 25.73
45 INT5131 Gene_expression of GNRH1 1 109 0.78 28.79 23.94
46 INT9526 Negative_regulation of Localization of Pomc 1 41 0.58 6.93 23.3
47 INT3330 Gene_expression of AGT 1 149 0.76 98.65 22.73
48 INT57253 Negative_regulation of Binding of Oprm1 1 24 0.43 5.27 22.67
49 INT3359 Regulation of YY1 1 32 0.60 8.19 19.2
50 INT31905 Positive_regulation of Binding of Oprd1 1 21 0.66 3.31 18.44
51 INT8332 Positive_regulation of OPRD1 1 30 0.61 3.88 17.65
52 INT26972 Negative_regulation of Tenc1 1 57 0.57 56.71 16.87
53 INT15102 Gene_expression of Trim13 2 18 0.67 0.43 15.49
54 INT12658 Regulation of Binding of Oprm1 1 9 0.57 2.44 14.95
55 INT2758 Binding of Dbp 2 36 0.44 8.3 14.47
56 INT26975 Gene_expression of Adipoq 1 113 0.75 106.71 14.46
57 INT13498 Gene_expression of Atxn2l 1 16 0.52 1.24 13.73
58 INT17938 Binding of Cpe 1 28 0.48 11.17 13.62
59 INT35467 Gene_expression of DIO2 1 37 0.65 9.56 12.61
60 INT26973 Gene_expression of Tenc1 1 59 0.66 27.19 12
61 INT2260 Gene_expression of Tyr 5 30 0.49 7.05 11.31
62 INT2956 Binding of H2-Ab1 1 19 0.37 3.1 11.18
63 INT36715 Gene_expression of Trpc4 1 50 0.68 4.18 11.13
64 INT29988 Gene_expression of Mecp2 2 27 0.78 5.45 9.47
65 INT43811 Positive_regulation of Tyr 1 14 0.45 2.52 8.86
66 INT8637 Negative_regulation of Dbp 1 112 0.50 33.28 8.4
67 INT18185 Gene_expression of Tyr 1 32 0.76 12.52 8.17
68 INT46812 Gene_expression of Tac2 1 12 0.75 1.34 6.17
69 INT10675 Gene_expression of DBI 6 28 0.67 19.74 6.07
70 INT7527 Gene_expression of SLTM 1 12 0.25 2.9 6.07
71 INT8157 Binding of Tyr 1 14 0.09 0.64 5.89
72 INT17056 Gene_expression of DLD 2 37 0.57 13.15 5.47
73 INT33332 Positive_regulation of Binding of Insrr 1 6 0.38 0.77 3.94
74 INT28021 Positive_regulation of Adipoq 1 42 0.67 30.79 3.58
75 INT18662 Negative_regulation of Binding of PDYN 1 5 0.57 0.34 3.58
76 INT22502 Gene_expression of Hal 1 21 0.53 9.8 3.32
77 INT12796 Binding of DLD 2 20 0.36 6.71 3.02
78 INT26974 Negative_regulation of Adipoq 2 27 0.52 26.01 2.59
79 INT43483 Gene_expression of DLL4 2 7 0.60 0.89 2.59
80 INT1829 Gene_expression of CFH 2 71 0.75 64.24 2.49
81 INT12657 Regulation of Pcsk1n 1 3 0.44 0.52 2.04
82 INT46142 Gene_expression of Chka 1 18 0.19 16.4 1.84
83 INT42277 Gene_expression of GIPC1 1 6 0.25 2.06 1.61
84 INT6438 Positive_regulation of RAN 1 6 0.42 2.09 1.59
85 INT29986 Binding of Fcer2a 1 9 0.27 4.34 1.38
86 INT36410 Gene_expression of Rere 1 5 0.58 1 1.37
87 INT29997 Binding of Ptger3 1 5 0.17 3.32 1.34
88 INT44573 Gene_expression of Del(7)Tyr<c-3H>-p 3 5 0.35 0 1.33
89 INT29416 Positive_regulation of Binding of OPRD1 1 2 0.47 0.52 1.31
90 INT33562 Negative_regulation of Mtss1 1 2 0.36 0.61 1.2
91 INT29985 Positive_regulation of Binding of Fcer2a 1 1 0.00 0 1.04
92 INT7351 Gene_expression of NPS 1 5 0.58 1.87 0.88
93 INT42684 Gene_expression of PHYHIP 1 2 0.58 0.34 0.85
94 INT28020 Binding of Adipoq 1 10 0.36 11.49 0.77
95 INT16003 Gene_expression of Phex 1 3 0.65 4.68 0.77
96 INT23468 Gene_expression of Fbn1 1 7 0.76 8.04 0.76
97 INT29998 Binding of H51 1 1 0.02 0 0.66
98 INT26971 Gene_expression of Ppp1r18 1 2 0.15 0 0.48
99 INT13381 Regulation of Binding of YY1 1 2 0.44 0 0.46
100 INT46107 Gene_expression of CTAG2 1 4 0.76 0.55 0.38
101 INT42846 Regulation of Binding of Cpe 1 1 0.01 0 0.38
102 INT46104 Gene_expression of Clip4 1 1 0.01 0 0.36
103 INT46103 Gene_expression of Tdp2 1 1 0.01 0 0.36
104 INT28023 Negative_regulation of Dap 1 1 0.35 0 0.29
105 INT42278 Binding of GIPC1 1 3 0.03 0.33 0.26
106 INT37816 Gene_expression of LYVE1 1 1 0.05 0 0.26
107 INT42386 Gene_expression of OR1L3 1 1 0.01 0 0.26
108 INT10769 Positive_regulation of NR3C2 1 2 0.10 0.39 0.24
109 INT13867 Negative_regulation of Regulation of YY1 1 1 0.41 0 0.21
110 INT26976 Gene_expression of T(2D;11B5)4Dn 1 1 0.14 0 0.2
111 INT28025 Binding of Dap 1 2 0.23 0 0.17
112 INT28022 Positive_regulation of Dap 1 1 0.28 0 0.17
113 INT28026 Positive_regulation of Binding of Adipoq 1 1 0.27 0 0.17
114 INT28024 Positive_regulation of Binding of Dap 1 1 0.30 0 0.17
115 INT40461 Positive_regulation of SPAG11B 1 1 0.07 0 0.15
116 INT17258 Regulation of Nrg2 1 1 0.00 0 0.13
117 INT17259 Regulation of Nrg4 1 1 0.00 0 0.13
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