J:Int Semin Surg Oncol

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT197111 Binding of IL1B and MCF2 1 2 0.02 2.12 1.4
2 INT173059 Binding of KDR and VEGFA 43 1 0.43 29.63 1.1
3 INT65985 IL1B Positive_regulation of Gene_expression of PTGS2 3 1 0.23 2.62 0.71
4 INT197115 Binding of MCF2 and RETNLB 1 1 0.00 1.06 0.7
5 INT197113 RETNLB Regulation of IL1B 1 2 0.00 1.27 0.44
6 INT197112 Binding of IL1B and TP53TG3 1 1 0.03 1.17 0.31
7 INT197114 IL1B Regulation of Binding of MCF2 1 1 0.03 0.48 0.31
8 INT191718 Binding of FLT1 and VEGFA 35 1 0.50 12.18 0.27
9 INT232559 Map3k1 Positive_regulation of Esr1 1 1 0.19 0.26 0.09
10 INT232557 Erbb2 Positive_regulation of Esr1 1 1 0.23 0.26 0.09
11 INT232558 Binding of Erbb2 and Esr1 1 1 0.24 0.59 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3 3152 0.78 2515.62 929.82
2 INT1912 Gene_expression of Calca 1 1152 0.78 453.25 739.84
3 INT49750 Negative_regulation of CPOX 1 735 0.58 360.06 274.19
4 INT5972 Gene_expression of IL1B 4 948 0.78 510.91 263.97
5 INT68684 Gene_expression of VEGFA 21 2371 0.78 1742.52 259.2
6 INT50674 Gene_expression of PTGS2 1 459 0.78 253.33 118.51
7 INT18009 Positive_regulation of CRP 2 518 0.70 553.03 103.74
8 INT11381 Positive_regulation of IL1B 2 330 0.70 209.31 100.9
9 INT9236 Regulation of Gene_expression of TNF 2 204 0.62 162.66 72.99
10 INT11380 Negative_regulation of IL1B 1 215 0.59 125.62 72.35
11 INT79494 Positive_regulation of Gene_expression of VEGFA 1 577 0.70 442.94 69.73
12 INT6849 Localization of IL1B 1 229 0.81 112.56 69.63
13 INT5374 Gene_expression of Esr1 2 412 0.77 263.89 67.34
14 INT822 Gene_expression of ESR1 3 529 0.78 302.16 63.64
15 INT9408 Positive_regulation of Crp 1 296 0.69 242.27 57.35
16 INT5623 Positive_regulation of Nppa 2 174 0.70 69.96 52.33
17 INT6473 Positive_regulation of Gene_expression of IL1B 1 204 0.70 117.23 50.86
18 INT65889 Gene_expression of RETNLB 1 73 0.34 60.98 38.3
19 INT63349 Gene_expression of PECAM1 3 199 0.75 166.03 36.76
20 INT6484 Binding of IL1B 1 122 0.47 75.84 35.07
21 INT79060 Gene_expression of NOS2 1 116 0.78 69.25 34.84
22 INT1624 Gene_expression of Cea 1 212 0.76 180.44 34.21
23 INT99688 Negative_regulation of Gene_expression of VEGFA 2 274 0.58 201.8 31.1
24 INT37296 Binding of Esr1 1 117 0.43 62.51 27.33
25 INT17739 Gene_expression of S100B 1 226 0.78 132.7 26.4
26 INT5622 Gene_expression of Nppa 2 101 0.78 49.46 25.31
27 INT6868 Gene_expression of GFAP 1 136 0.78 84.65 22.7
28 INT91891 Gene_expression of Kit 2 268 0.78 158.89 22.67
29 INT2386 Gene_expression of Pgr 1 112 0.78 45.46 22.19
30 INT48692 Binding of VEGFA 1 345 0.48 210.3 21.31
31 INT68683 Regulation of Gene_expression of VEGFA 2 143 0.62 104.19 20.14
32 INT4067 Negative_regulation of Esr1 1 97 0.50 43.45 17.52
33 INT1767 Positive_regulation of PROC 1 83 0.67 54.14 17
34 INT13510 Gene_expression of ERBB2 1 530 0.78 405.68 16.79
35 INT27242 Gene_expression of PGR 2 153 0.75 98.77 12.79
36 INT2673 Negative_regulation of PROC 2 93 0.57 50.34 12.79
37 INT24876 Gene_expression of CD34 4 172 0.78 91.02 12.39
38 INT37390 Regulation of Crp 1 39 0.46 28.74 11.45
39 INT25963 Gene_expression of DES 1 122 0.75 98.81 11.25
40 INT94454 Gene_expression of CD68 1 73 0.72 63.94 10.43
41 INT67048 Gene_expression of ITGA4 1 58 0.75 28.93 10.16
42 INT23676 Gene_expression of Chrna7 1 47 0.75 23.66 9.51
43 INT64346 Positive_regulation of S100B 1 95 0.70 63.11 9.17
44 INT49325 Gene_expression of Cd34 2 102 0.78 82.75 8.97
45 INT69264 Gene_expression of KIT 1 207 0.78 179.41 8.95
46 INT144430 Gene_expression of Erbb2 31 137 0.77 103.87 8.66
47 INT6810 Gene_expression of ENO2 1 70 0.78 54.8 8.35
48 INT36798 Gene_expression of Mki67 1 178 0.77 132 8.24
49 INT167052 Gene_expression of Cr2 1 43 0.56 25.7 7.76
50 INT74520 Positive_regulation of CD68 1 30 0.61 31.68 7.59
51 INT79168 Binding of TNC 1 39 0.47 16.51 7.55
52 INT103154 Gene_expression of FLT1 1 138 0.76 58.5 7.41
53 INT6210 Binding of Nppa 2 39 0.47 14.35 7.21
54 INT6891 Binding of TTR 2 72 0.48 22.81 6.51
55 INT92916 Gene_expression of Acta2 1 50 0.74 17.52 6.11
56 INT15376 Positive_regulation of Gene_expression of ERBB2 1 215 0.70 168.54 5.23
57 INT15652 Positive_regulation of ENO2 1 37 0.68 33.39 5.02
58 INT37661 Negative_regulation of SERPINC1 1 48 0.59 38.6 4.77
59 INT82354 Positive_regulation of PECAM1 1 25 0.34 22.93 4.69
60 INT14470 Gene_expression of HCC 1 83 0.67 110.55 4.61
61 INT35609 Negative_regulation of F10 1 37 0.57 17.15 4.41
62 INT103155 Gene_expression of KDR 1 78 0.66 50.53 4.38
63 INT21681 Positive_regulation of CD34 1 54 0.66 33.95 4.14
64 INT144428 Positive_regulation of Gene_expression of Erbb2 15 41 0.69 41.4 4.13
65 INT88278 Binding of Kit 2 33 0.37 24.45 4.13
66 INT4988 Gene_expression of KRT1 1 64 0.77 43.4 4.12
67 INT111477 Gene_expression of KRT7 1 90 0.74 86.76 4.07
68 INT4649 Positive_regulation of Chrna7 2 17 0.50 5.48 3.92
69 INT124655 Negative_regulation of PECAM1 1 13 0.23 10.32 3.78
70 INT124185 Negative_regulation of Kit 2 57 0.59 35.43 3.61
71 INT95652 Gene_expression of Krt20 1 54 0.61 53.69 3.31
72 INT11775 Gene_expression of Ema 1 39 0.65 38.12 2.99
73 INT121493 Gene_expression of XRCC1 3 55 0.65 73.43 2.76
74 INT71794 Binding of SERPINC1 1 17 0.39 10.5 2.64
75 INT97902 Gene_expression of AGGF1 2 17 0.11 13.45 2.51
76 INT70297 Gene_expression of NEFH 1 12 0.75 4.85 2.33
77 INT59784 Binding of DES 1 22 0.47 19.48 2.27
78 INT97973 Positive_regulation of XRCC1 1 24 0.40 30.95 2.26
79 INT83896 Gene_expression of CD1A 2 19 0.68 15.58 2.1
80 INT56342 Gene_expression of TTR 1 34 0.78 16.5 2.05
81 INT44223 Positive_regulation of TTR 1 10 0.70 10.98 1.95
82 INT37216 Binding of SMN1 1 11 0.36 6.66 1.86
83 INT113147 Positive_regulation of Acta2 1 6 0.34 4.24 1.66
84 INT89445 Gene_expression of MEPE 1 17 0.58 18.07 1.55
85 INT18844 Binding of IAPP 1 11 0.36 11.01 1.45
86 INT214073 Binding of TSC1 2 9 0.37 22 1.34
87 INT66852 Gene_expression of Fcer2 1 15 0.14 9.74 1.27
88 INT74018 Binding of XRCC1 1 19 0.31 24.78 1.24
89 INT20757 Binding of MCF2 1 4 0.07 0.71 0.95
90 INT88718 Negative_regulation of Erbb2 2 11 0.58 12.98 0.84
91 INT173100 Binding of KDR 1 39 0.39 22.48 0.81
92 INT186483 Negative_regulation of MYOM2 1 3 0.04 2.92 0.79
93 INT36200 Gene_expression of S100A1 1 9 0.77 9.56 0.75
94 INT15783 Regulation of SMS 1 6 0.23 3.2 0.75
95 INT191194 Localization of MCF2 1 7 0.11 2.29 0.65
96 INT154706 Gene_expression of Tg 1 9 0.38 4.95 0.64
97 INT160961 Gene_expression of Fth1 1 4 0.28 3.89 0.63
98 INT128472 Negative_regulation of CD34 1 7 0.42 3.92 0.58
99 INT60115 Transcription of F8 1 2 0.08 3.05 0.58
100 INT197117 Negative_regulation of Localization of MCF2 1 1 0.03 0.81 0.56
101 INT173748 Phosphorylation of Esr1 1 11 0.77 5.7 0.55
102 INT7293 Negative_regulation of Binding of Nppa 1 5 0.43 1.4 0.55
103 INT143125 Binding of FLT1 1 48 0.40 13.6 0.51
104 INT202196 Transcription of Erbb2 1 3 0.69 3.87 0.51
105 INT211264 Gene_expression of Hk2 7 7 0.56 12.12 0.46
106 INT186480 Positive_regulation of Transcription of F8 1 1 0.06 2.08 0.4
107 INT186482 Regulation of Transcription of ANGPTL5 1 1 0.03 2.05 0.4
108 INT83212 Positive_regulation of Gene_expression of Mki67 1 21 0.55 17.53 0.39
109 INT186481 Transcription of ANGPTL5 1 1 0.04 2.04 0.39
110 INT199559 Binding of Erbb2 1 5 0.36 4.23 0.36
111 INT103806 Negative_regulation of Aaiq4 1 4 0.41 3.72 0.31
112 INT181756 Positive_regulation of Erbb2 1 6 0.46 4.12 0.28
113 INT166125 Gene_expression of PHOSPHO1 1 4 0.75 3.06 0.24
114 INT180264 Positive_regulation of BCC1 3 11 0.59 12.81 0.2
115 INT183473 Negative_regulation of SMS 1 3 0.35 2.14 0.2
116 INT228901 Positive_regulation of RPS6KB1 1 5 0.55 2.44 0.18
117 INT180265 Localization of BCC1 2 7 0.65 9.48 0.15
118 INT211265 Positive_regulation of Gene_expression of Hk2 3 1 0.04 2.26 0.14
119 INT232556 Positive_regulation of Phosphorylation of Esr1 2 1 0.20 0.41 0.12
120 INT228902 Gene_expression of RPS6KB1 1 5 0.75 2.32 0.1
121 INT232550 Negative_regulation of Gene_expression of Erbb2 2 9 0.43 4.96 0.07
122 INT211261 Negative_regulation of Hk2 1 1 0.03 0.92 0.03
123 INT228895 Binding of Tsc2 1 5 0.30 2.41 0
124 INT228900 Positive_regulation of Gene_expression of RPS6KB1 1 2 0.49 1.6 0
125 INT228904 Positive_regulation of PHOSPHO1 1 1 0.45 0.84 0
126 INT232554 Negative_regulation of Transcription of Erbb2 1 1 0.42 1.16 0
127 INT232555 Negative_regulation of Gene_expression of Sh3pxd2a 1 1 0.08 1.22 0
128 INT228899 Positive_regulation of Gene_expression of PHOSPHO1 1 1 0.49 0.84 0
129 INT211262 Regulation of Gene_expression of Hk2 1 1 0.03 0.87 0
130 INT232553 Binding of Sh3pxd2a 1 1 0.07 0.52 0
131 INT232552 Negative_regulation of Sh3pxd2a 1 1 0.08 1.22 0
132 INT228903 Negative_regulation of Gene_expression of PHOSPHO1 1 1 0.42 0.79 0
133 INT232551 Gene_expression of Sh3pxd2a 2 1 0.14 1.32 0
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