J:International Journal of Alzheimer's Disease

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT328228 Binding of Cpox and Hmox1 1 1 0.03 0.83 0.23
2 INT256629 Binding of Ptch1 and Shh 7 2 0.42 4.22 0.19
3 INT340744 CSF2 Regulation of BDNF 1 1 0.13 1.45 0.14
4 INT340742 Positive_regulation of CSF2 Regulation of BDNF 1 1 0.22 1.46 0.14
5 INT329946 Binding of Stmn2 and Trpc5 1 1 0.03 0.15 0
6 INT325431 Positive_regulation of Binding of Csf2 and Mapt 1 1 0.18 1.49 0
7 INT325429 Mapt Positive_regulation of Csf2 1 1 0.13 1.29 0
8 INT340743 Negative_regulation of CSF2 Positive_regulation of ZNF807 1 1 0.00 1.77 0
9 INT340745 CSF2 Positive_regulation of ZNF807 1 1 0.00 1.76 0
10 INT329945 Binding of Trpc5 and Negr1 1 1 0.00 0.15 0
11 INT325428 Csf2 Regulation of Mapt 1 1 0.08 1.47 0
12 INT325433 Binding of Csf2 and Mapt 1 3 0.12 4.41 0
13 INT325430 Vsnl1 Positive_regulation of Vhl-ps1 1 1 0.03 1.01 0
14 INT325432 Vsnl1 Positive_regulation of Csf2 1 1 0.19 1.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 1 3152 0.78 2515.62 929.82
2 INT9659 Gene_expression of Il6 3 991 0.78 715.11 265.57
3 INT6488 Gene_expression of Tnf 3 484 0.78 339.61 191.58
4 INT49441 Negative_regulation of Cpox 2 494 0.59 303.22 177.46
5 INT49439 Gene_expression of Cpox 16 508 0.73 326.97 130.17
6 INT8243 Positive_regulation of Il6 2 451 0.70 358.24 119.28
7 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 6 1138 0.72 311.58 119.18
8 INT12082 Localization of IL6 1 365 0.81 241.78 105.78
9 INT65500 Gene_expression of App 21 605 0.78 429.94 98.31
10 INT11587 Gene_expression of CSF2 26 645 0.78 544.38 93.89
11 INT6489 Positive_regulation of Gene_expression of Tnf 2 140 0.70 92.31 67.85
12 INT102546 Gene_expression of Ccl2 1 197 0.78 192.8 67.41
13 INT4960 Positive_regulation of CSF2 7 285 0.70 256.73 65.73
14 INT9657 Positive_regulation of Gene_expression of Il6 2 237 0.70 180.45 63.6
15 INT63975 Positive_regulation of Il10 1 175 0.68 134.13 54.69
16 INT1199 Positive_regulation of INS 1 579 0.70 399.64 50.43
17 INT25383 Gene_expression of Csf2 7 222 0.76 152.93 43.32
18 INT3252 Negative_regulation of INS 1 428 0.59 271.65 39.52
19 INT3679 Gene_expression of AVP 1 171 0.78 72.9 35.23
20 INT67039 Positive_regulation of Cpox 7 144 0.65 98.4 33.77
21 INT9694 Positive_regulation of Csf2 5 102 0.68 70.09 33.07
22 INT10248 Gene_expression of KRT20 2 436 0.78 231.96 32.88
23 INT73982 Gene_expression of Hmox1 4 141 0.78 119.43 32.17
24 INT29743 Negative_regulation of App 3 91 0.59 65.56 31.26
25 INT32165 Binding of CALM1 1 92 0.48 24.19 29.57
26 INT11554 Negative_regulation of CSF2 12 129 0.59 108.55 29.44
27 INT47712 Positive_regulation of App 5 135 0.69 101.38 28.94
28 INT48853 Positive_regulation of BDNF 3 82 0.69 43.92 27.99
29 INT116861 Gene_expression of Apoe 2 182 0.78 100.41 27.26
30 INT14690 Localization of CSF2 2 124 0.80 85.17 27.26
31 INT13995 Gene_expression of gr 1 96 0.74 48.21 26.54
32 INT89662 Positive_regulation of Gene_expression of App 4 169 0.70 133.36 25.62
33 INT682 Negative_regulation of AVP 1 97 0.59 50.67 23.91
34 INT44954 Gene_expression of APP 8 191 0.78 105.86 23.9
35 INT69993 Positive_regulation of Gene_expression of Cpox 2 93 0.55 69.4 22.05
36 INT11625 Localization of App 6 98 0.78 55.46 20.86
37 INT111401 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 3 134 0.61 34.87 20.15
38 INT16794 Binding of App 4 103 0.48 64.87 19.79
39 INT65502 Regulation of App 1 77 0.62 52.05 19.44
40 INT23533 Gene_expression of CA2 1 110 0.75 30.81 19.4
41 INT756 Gene_expression of C3 1 138 0.75 100.6 19.2
42 INT80223 Positive_regulation of Hmox1 4 128 0.68 77.71 17.64
43 INT23657 Positive_regulation of APP 1 64 0.70 39.76 16.68
44 INT1020 Negative_regulation of BCHE 3 109 0.59 44.86 16.4
45 INT11685 Regulation of CSF2 1 99 0.59 58.82 15.9
46 INT111073 Gene_expression of Psen1 6 167 0.76 78.65 15.83
47 INT131296 Positive_regulation of Bace1 1 208 0.70 170.1 15.79
48 INT62681 Negative_regulation of LEP 1 93 0.59 66.97 15.77
49 INT124371 Negative_regulation of Gsk3b 5 170 0.55 87.92 15.51
50 INT106745 Localization of CRP 1 65 0.81 66.44 15.21
51 INT124372 Gene_expression of Gsk3b 13 164 0.75 95.64 14.35
52 INT22301 Positive_regulation of Gene_expression of CSF2 3 66 0.63 59.49 14.24
53 INT80228 Positive_regulation of Gene_expression of Hmox1 2 68 0.70 62.88 14.01
54 INT1125 Positive_regulation of IGHG3 1 130 0.69 112.07 13.18
55 INT105670 Gene_expression of AAVS1 2 131 0.75 49.24 12.95
56 INT54763 Binding of Il6 1 82 0.48 63.27 12.89
57 INT27268 Localization of Gtf3a 1 71 0.21 56.93 12.51
58 INT29745 Binding of APP 1 47 0.48 26.49 12.4
59 INT107916 Protein_catabolism of App 4 114 1.00 66.71 12.38
60 INT107033 Gene_expression of Slc37a4 1 66 0.62 27.34 12.35
61 INT100821 Localization of Ros1 2 59 0.60 45.26 11.92
62 INT83611 Negative_regulation of Gene_expression of Cpox 3 55 0.29 31.09 11.5
63 INT65501 Regulation of Gene_expression of App 2 56 0.62 32.51 11.48
64 INT98789 Negative_regulation of Gene_expression of App 3 54 0.58 40.27 11.15
65 INT91774 Gene_expression of Nr3c1 1 27 0.78 16.14 10.7
66 INT82950 Positive_regulation of Gdnf 1 36 0.51 11.72 10.5
67 INT49129 Positive_regulation of GFAP 2 35 0.69 28.78 10.38
68 INT75768 Transcription of Cpox 1 37 0.27 19.41 9.79
69 INT135407 Negative_regulation of Ccl2 1 33 0.57 32.74 9.45
70 INT135372 Positive_regulation of Gsk3b 3 72 0.70 50.03 9.28
71 INT147452 Gene_expression of ADCYAP1 2 14 0.77 12.54 9.28
72 INT28312 Gene_expression of ABCA1 1 85 0.72 37.69 9.27
73 INT46273 Gene_expression of PRNP 1 103 0.78 110.34 9.25
74 INT64346 Positive_regulation of S100B 2 95 0.70 63.11 9.17
75 INT138700 Negative_regulation of Gene_expression of Ccl2 1 27 0.57 24.1 9.08
76 INT25381 Localization of Csf2 2 62 0.76 47.48 9.03
77 INT14301 Binding of CSF2 4 82 0.48 67.95 8.98
78 INT108931 Negative_regulation of BDNF 1 38 0.59 19.61 8.84
79 INT3622 Regulation of CTSB 1 34 0.58 16.08 8.76
80 INT102658 Negative_regulation of Gene_expression of CSF2 1 42 0.50 38.63 8.32
81 INT77249 Positive_regulation of Gene_expression of gr 1 24 0.67 16.09 8.17
82 INT7813 Regulation of SRI 1 25 0.61 6.18 8.13
83 INT75932 Binding of Csf2 3 45 0.37 33.2 8.01
84 INT50290 Binding of Cpox 1 29 0.27 17.19 8.01
85 INT67037 Gene_expression of Sod1 1 121 0.78 59.32 7.99
86 INT71689 Localization of Ntf3 1 23 0.73 11.1 7.91
87 INT113705 Gene_expression of Egfr 1 228 0.78 149.05 7.59
88 INT182750 Gene_expression of Hmgcr 1 61 0.58 17.23 7.4
89 INT84932 Negative_regulation of APP 1 29 0.57 28.45 7.2
90 INT18340 Gene_expression of CRX 1 16 0.22 13.85 7.13
91 INT55957 Positive_regulation of PRNP 3 57 0.67 37.87 7.11
92 INT90275 Negative_regulation of Ppp1cc 1 29 0.58 1.91 7.11
93 INT182351 Positive_regulation of Gene_expression of Apoe 1 38 0.50 19.78 6.72
94 INT168641 Gene_expression of Iba1 1 24 0.63 12.21 6.7
95 INT211701 Positive_regulation of Mri1 1 20 0.34 20.64 6.69
96 INT8595 Localization of Mapt 2 26 0.73 6.81 6.41
97 INT9695 Negative_regulation of Csf2 9 41 0.57 31.65 6.28
98 INT46721 Regulation of Csf2 1 26 0.45 20.4 6.18
99 INT135170 Positive_regulation of Hif1a 1 86 0.67 99.4 6.07
100 INT84572 Gene_expression of Zmat3 4 67 0.07 37.61 5.86
101 INT25394 Negative_regulation of Gene_expression of Csf2 2 22 0.52 13.18 5.84
102 INT49440 Localization of Cpox 1 27 0.53 11.26 5.79
103 INT38671 Positive_regulation of KRT20 1 62 0.53 40.17 5.6
104 INT124370 Positive_regulation of Gene_expression of Gsk3b 7 47 0.67 24.56 5.4
105 INT163913 Gene_expression of Il11ra1 2 18 0.69 12.62 5.34
106 INT134468 Gene_expression of Cdk5r1 1 26 0.48 27.09 5.2
107 INT24080 Negative_regulation of Mtor 1 64 0.37 41.56 5.19
108 INT129508 Localization of Cacna1a 1 7 0.74 6.47 5.13
109 INT99823 Positive_regulation of Gene_expression of APP 2 31 0.70 21.52 5.09
110 INT115816 Protein_catabolism of APP 1 35 0.99 20.14 5.06
111 INT135374 Binding of Gsk3b 2 46 0.48 24.36 4.75
112 INT75627 Gene_expression of Mapt 8 41 0.75 22.1 4.58
113 INT168640 Positive_regulation of Gene_expression of Iba1 1 9 0.33 8.3 4.55
114 INT29809 Gene_expression of Tspo 2 8 0.75 4.12 4.54
115 INT97254 Positive_regulation of Gap43 1 22 0.46 7.36 4.48
116 INT72703 Gene_expression of Ide 2 79 0.70 45.04 4.47
117 INT111066 Regulation of Bace1 1 40 0.61 31.47 4.28
118 INT34624 Negative_regulation of REM1 1 22 0.38 9.25 4.22
119 INT167284 Phosphorylation of Gsk3b 3 88 0.82 36.03 4.21
120 INT111067 Positive_regulation of Gene_expression of Psen1 2 32 0.68 21.2 4.19
121 INT220594 Localization of Bace1 1 48 0.79 20.22 4.16
122 INT99821 Negative_regulation of Gene_expression of APP 1 20 0.42 15.21 3.94
123 INT3127 Gene_expression of SRI 1 38 0.68 26.29 3.82
124 INT19189 Localization of IL1A 1 14 0.78 9.02 3.78
125 INT11627 Positive_regulation of Localization of App 1 14 0.62 6.27 3.64
126 INT17496 Regulation of Maob 1 7 0.60 6.49 3.62
127 INT52047 Gene_expression of APOE 1 50 0.78 34.75 3.52
128 INT80224 Regulation of Hmox1 1 19 0.32 10.53 3.52
129 INT36716 Positive_regulation of Gene_expression of Tspo 2 4 0.68 3.48 3.49
130 INT131165 Positive_regulation of Gene_expression of Nr3c1 1 8 0.70 7.18 3.44
131 INT70089 Negative_regulation of Binding of APP 1 7 0.59 6.45 3.44
132 INT110245 Gene_expression of SNCA 2 11 0.77 8.29 3.36
133 INT117117 Positive_regulation of REM1 1 12 0.40 10.1 3.33
134 INT48390 Negative_regulation of Localization of CSF2 1 10 0.51 7.39 3.28
135 INT38987 Protein_catabolism of INS 1 21 0.99 11.92 2.91
136 INT178772 Transcription of App 1 17 0.70 10.79 2.79
137 INT13382 Negative_regulation of Maob 1 13 0.57 11.73 2.72
138 INT59454 Regulation of Gene_expression of CSF2 1 22 0.52 19.67 2.69
139 INT110980 Gene_expression of CTSB 1 17 0.45 8.02 2.69
140 INT50080 Binding of APOE 1 38 0.45 29.61 2.67
141 INT91899 Binding of Sod1 1 17 0.47 11.56 2.63
142 INT23775 Regulation of S100B 1 24 0.62 16.75 2.57
143 INT63238 Gene_expression of Mt1 2 27 0.65 10.86 2.53
144 INT122656 Gene_expression of MTNR1A 1 21 0.75 6.37 2.46
145 INT44880 Gene_expression of REM1 1 21 0.30 5.3 2.43
146 INT163544 Binding of Psen1 1 40 0.36 15.28 2.42
147 INT29094 Binding of C3 1 39 0.37 12.65 2.27
148 INT142265 Regulation of Apoe 1 20 0.60 9.52 2.23
149 INT237252 Localization of Mri1 1 7 0.45 4.42 2.23
150 INT161382 Localization of KRT20 1 25 0.61 12.97 2.13
151 INT181507 Positive_regulation of Psen1 3 22 0.49 7.59 2.04
152 INT58432 Positive_regulation of Gsr 1 12 0.70 9.4 1.94
153 INT258135 Gene_expression of CARTPT 3 3 0.40 5.25 1.88
154 INT3866 Positive_regulation of Positive_regulation of INS 1 30 0.59 21.58 1.86
155 INT111070 Negative_regulation of Gene_expression of Psen1 1 17 0.42 9.47 1.77
156 INT58563 Negative_regulation of S100B 1 13 0.51 11.75 1.77
157 INT163613 Transcription of CSF2 1 16 0.60 12.98 1.62
158 INT183761 Phosphorylation of Csf2 1 6 0.80 4.04 1.58
159 INT62127 Localization of SRI 3 12 0.45 10.21 1.54
160 INT57785 Positive_regulation of SGCB 1 25 0.69 5.01 1.49
161 INT7812 Negative_regulation of SRI 1 10 0.59 4.28 1.46
162 INT125796 Regulation of Gene_expression of APP 1 8 0.59 5.95 1.41
163 INT191970 Positive_regulation of Ide 1 29 0.51 12.94 1.4
164 INT181509 Negative_regulation of Psen1 1 17 0.57 11.53 1.35
165 INT148883 Gene_expression of HCRTR1 1 8 0.36 24.82 1.35
166 INT61999 Gene_expression of MAPT 5 19 0.75 15.4 1.3
167 INT139077 Negative_regulation of Ptch1 1 5 0.56 5.22 1.29
168 INT155946 Positive_regulation of Mt1 2 7 0.45 4.31 1.23
169 INT110244 Positive_regulation of Gene_expression of SNCA 2 5 0.69 4.66 1.19
170 INT63923 Binding of Mapt 7 4 0.47 6.28 1.19
171 INT85621 Regulation of PRNP 4 16 0.60 8.7 1.15
172 INT183046 Transcription of INS 1 25 0.70 11.14 1.13
173 INT199187 Localization of Hmox1 3 2 0.78 3.36 1.11
174 INT47027 Positive_regulation of BCHE 1 6 0.50 2.32 1.09
175 INT8594 Negative_regulation of Mapt 3 5 0.57 4.47 0.98
176 INT70323 Negative_regulation of Gene_expression of CA2 2 13 0.41 6.55 0.97
177 INT15310 Gene_expression of DLEU1 10 8 0.67 20.57 0.96
178 INT141936 Phosphorylation of Mapt 9 14 0.80 10.59 0.95
179 INT285477 Positive_regulation of Zeb1 1 2 0.17 0.86 0.86
180 INT24142 Regulation of DLEU1 1 1 0.21 1.01 0.85
181 INT167285 Positive_regulation of Phosphorylation of Gsk3b 1 17 0.50 5.92 0.82
182 INT327363 Negative_regulation of Ttr 2 8 0.40 8.21 0.82
183 INT131286 Binding of Egfr 1 26 0.44 13.58 0.78
184 INT197494 Gene_expression of Apoa4 3 9 0.05 7.33 0.78
185 INT328226 Negative_regulation of Positive_regulation of Cpox 1 3 0.11 1.49 0.73
186 INT242137 Negative_regulation of Positive_regulation of Gsk3b 2 7 0.39 2.99 0.67
187 INT202344 Positive_regulation of Map3k3 1 7 0.49 2.08 0.67
188 INT206139 Phosphorylation of KRT20 3 8 0.48 9.1 0.66
189 INT191978 Positive_regulation of Gene_expression of Ide 1 16 0.63 6.8 0.65
190 INT59137 Protein_catabolism of CTSB 1 5 0.96 3.92 0.62
191 INT325408 Gene_expression of C330021F23Rik 3 1 0.19 2.56 0.62
192 INT63133 Gene_expression of Pd 1 13 0.18 5.31 0.61
193 INT236837 Regulation of Negative_regulation of CSF2 1 2 0.32 1.83 0.61
194 INT14318 Negative_regulation of MAPT 2 3 0.57 2.05 0.59
195 INT310648 Negative_regulation of Negative_regulation of BCHE 1 2 0.27 1.79 0.59
196 INT65919 Gene_expression of Ptch1 2 11 0.75 6.47 0.56
197 INT210522 Protein_catabolism of Ide 1 16 0.79 7.73 0.55
198 INT225462 Positive_regulation of Positive_regulation of APP 1 3 0.44 1.41 0.55
199 INT118716 Positive_regulation of MAPT 2 4 0.49 7.25 0.54
200 INT148884 Negative_regulation of HCRTR1 1 7 0.23 7.23 0.53
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