J:International Journal of Nanomedicine

From wiki-pain
Jump to: navigation, search

This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT258798 Binding of NR3C1 and HSP90AA1 1 1 0.01 1.09 0.78
2 INT152429 Ghrh Positive_regulation of Localization of Gh 4 1 0.37 0.56 0.75
3 INT260551 Igh-Dex Negative_regulation of Il6 1 1 0.09 0.37 0.72
4 INT156667 Gh Positive_regulation of Gene_expression of Igf1 6 1 0.28 0.88 0.56
5 INT323352 Binding of F8 and VWF 5 2 0.08 2.22 0.33
6 INT268236 Binding of TNF and fc 1 1 0.04 0.2 0.29
7 INT268797 Ghrh Positive_regulation of Transcription of Gh 1 2 0.20 0.33 0.19
8 INT268279 Positive_regulation of Binding of Aggf1 and Alms1 1 1 0.02 0.15 0.18
9 INT268280 Binding of Aggf1 and Alms1 1 1 0.01 0.15 0.18
10 INT352488 Binding of EPO and TNFRSF1A 1 1 0.14 0.18 0.12
11 INT268798 Binding of Gh and Ghr 1 3 0.26 1.18 0.04
12 INT331881 F2 Positive_regulation of F8 1 1 0.10 0.53 0.03
13 INT235800 Twist1 Positive_regulation of VEGFA 1 1 0.02 0.62 0.03
14 INT260562 Binding of ALB and ANGPTL5 1 1 0.10 0.21 0
15 INT331875 Binding of GCG and Mst1r 1 1 0.08 0 0
16 INT331866 Binding of Csf2 and Mest 1 2 0.08 0 0
17 INT268258 Binding of hb and Ugt1a10 1 1 0.00 1.18 0
18 INT260561 Binding of AFM and PRNP 1 1 0.22 0 0
19 INT331874 Positive_regulation of Binding of GCG and Mst1r 1 1 0.11 0 0
20 INT331861 Binding of Csf3 and Mst1r 1 2 0.08 0 0
21 INT331864 Binding of Mest and Mst1r 1 2 0.52 0.28 0
22 INT235787 Binding of NR5A1 and HGF 1 1 0.02 0 0
23 INT331880 Binding of GCG and Mest 1 1 0.08 0 0
24 INT331878 Binding of F8 and Mst1r 1 1 0.33 0.2 0
25 INT331867 Binding of Csf3 and Mest 1 2 0.08 0 0
26 INT268809 Binding of IFNA2 and PAEP 1 1 0.01 0.16 0
27 INT331877 Binding of F8 and Mest 1 4 0.49 0.41 0
28 INT331865 Positive_regulation of Binding of Csf2 and Mst1r 1 2 0.11 0 0
29 INT331873 Regulation of Binding of F8 and Mest 1 1 0.46 0 0
30 INT268887 Binding of ANGPT1 and Tek 1 2 0.10 0 0
31 INT331869 Positive_regulation of Binding of Csf3 and Mst1r 1 2 0.11 0 0
32 INT331868 Positive_regulation of Binding of Csf2 and Mest 1 2 0.11 0 0
33 INT331862 Positive_regulation of Binding of Csf3 and Mest 1 2 0.11 0 0
34 INT331879 Positive_regulation of Binding of GCG and Mest 1 1 0.11 0 0
35 INT331876 Binding of PAEP and Mst1r 1 2 0.05 0.39 0
36 INT331850 Binding of F8 and PAEP 1 1 0.04 0 0
37 INT268885 ANGPT1 Negative_regulation of Binding of ANGPT1 and Tek 1 1 0.02 0 0
38 INT331863 Binding of Csf2 and Mst1r 1 2 0.10 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 13 3152 0.78 2515.62 929.82
2 INT9238 Gene_expression of IL6 2 1575 0.78 1135.66 424.22
3 INT5235 Negative_regulation of TNF 1 924 0.59 772.91 331.98
4 INT5059 Positive_regulation of TNF 2 1050 0.70 896.51 322.81
5 INT6852 Localization of TNF 1 883 0.81 705.95 270.84
6 INT10832 Gene_expression of IL8 2 1050 0.78 698.72 270
7 INT9659 Gene_expression of Il6 7 991 0.78 715.11 265.57
8 INT5972 Gene_expression of IL1B 1 948 0.78 510.91 263.97
9 INT68684 Gene_expression of VEGFA 4 2371 0.78 1742.52 259.2
10 INT1893 Localization of Gh 25 1041 0.79 340.23 256.58
11 INT6481 Binding of TNF 6 624 0.48 510.2 214.82
12 INT6488 Gene_expression of Tnf 1 484 0.78 339.61 191.58
13 INT10194 Positive_regulation of IL6 1 702 0.70 600.62 183.38
14 INT19472 Gene_expression of Il1 1 554 0.76 419.75 175.35
15 INT1114 Localization of Ins1 22 748 0.80 192.95 165.48
16 INT1114 Localization of Ins1 1 748 0.80 192.95 165.48
17 INT3448 Positive_regulation of Gh 8 521 0.69 180.03 161.18
18 INT9852 Positive_regulation of Gpt 5 563 0.70 364.64 146.82
19 INT9660 Regulation of TNF 4 363 0.62 312.94 139.99
20 INT65600 Positive_regulation of Casp3 4 376 0.70 198.44 128.03
21 INT8243 Positive_regulation of Il6 2 451 0.70 358.24 119.28
22 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 3 1138 0.72 311.58 119.18
23 INT5010 Gene_expression of Calca 1 197 0.78 85.76 118.75
24 INT9235 Negative_regulation of Gene_expression of TNF 1 346 0.59 252.98 118.61
25 INT1793 Localization of CGA 1 379 0.81 67.38 114.69
26 INT1530 Regulation of Gh 2 382 0.61 115.96 112.47
27 INT60526 Gene_expression of IL10 1 449 0.78 292.71 107.84
28 INT3038 Gene_expression of INS 2 1583 0.78 1174.16 107.01
29 INT18009 Positive_regulation of CRP 2 518 0.70 553.03 103.74
30 INT11381 Positive_regulation of IL1B 1 330 0.70 209.31 100.9
31 INT11587 Gene_expression of CSF2 1 645 0.78 544.38 93.89
32 INT5865 Positive_regulation of Localization of Gh 6 282 0.69 84.86 93.5
33 INT1472 Positive_regulation of Ins1 1 349 0.69 146.2 86.36
34 INT68682 Positive_regulation of VEGFA 2 640 0.70 454.14 81.65
35 INT1498 Gene_expression of Gh 17 521 0.75 220.84 81.16
36 INT3657 Gene_expression of Ins1 13 514 0.78 321.69 75.76
37 INT1497 Negative_regulation of Gh 9 415 0.59 192.95 74.71
38 INT56298 Gene_expression of IL4 1 306 0.78 182.18 72.92
39 INT79494 Positive_regulation of Gene_expression of VEGFA 2 577 0.70 442.94 69.73
40 INT170332 Gene_expression of IFN1@ 1 477 0.75 275.21 69.65
41 INT1988 Positive_regulation of Localization of Ins1 4 254 0.69 59.25 68.37
42 INT102546 Gene_expression of Ccl2 1 197 0.78 192.8 67.41
43 INT6486 Positive_regulation of Tnf 1 168 0.70 123.47 66.05
44 INT3375 Gene_expression of IGHE 1 535 0.77 387.47 65.46
45 INT9657 Positive_regulation of Gene_expression of Il6 1 237 0.70 180.45 63.6
46 INT17564 Gene_expression of Gpt 3 322 0.75 208.51 60.36
47 INT103924 Positive_regulation of Akt1 4 359 0.69 158.94 60.34
48 INT14740 Gene_expression of TGFB1 1 272 0.78 168.48 60.18
49 INT546 Binding of ALB 1 311 0.48 85.98 60.14
50 INT3161 Regulation of Localization of Gh 4 163 0.61 35.43 59.45
51 INT31116 Gene_expression of Casp3 1 192 0.78 78.21 57.43
52 INT4509 Gene_expression of IGG 1 426 0.76 293.69 56.64
53 INT1200 Negative_regulation of Ins1 5 274 0.58 155.17 56.14
54 INT2276 Regulation of Ins1 4 234 0.61 103.78 54.05
55 INT9234 Negative_regulation of Gene_expression of IL6 1 171 0.59 101.61 53.15
56 INT22112 Positive_regulation of Localization of TNF 1 164 0.70 115.66 52.18
57 INT249 Localization of GHRH 1 215 0.80 78.02 51.87
58 INT1199 Positive_regulation of INS 2 579 0.70 399.64 50.43
59 INT17881 Gene_expression of LEP 2 278 0.78 221.61 48.31
60 INT66029 Negative_regulation of Tnf 1 100 0.59 84.28 48.16
61 INT117598 Regulation of ACR 3 118 0.26 41.25 48.01
62 INT106525 Phosphorylation of Akt1 3 436 0.82 183.81 47.82
63 INT80124 Negative_regulation of VEGFA 2 450 0.58 311.19 44.53
64 INT1894 Negative_regulation of Localization of Gh 4 168 0.58 64.12 43.56
65 INT1474 Regulation of Localization of Ins1 3 132 0.61 25.96 43.07
66 INT1474 Regulation of Localization of Ins1 1 132 0.61 25.96 43.07
67 INT13556 Gene_expression of CD4 2 367 0.78 230.82 41.74
68 INT11939 Negative_regulation of Il6 1 138 0.59 87.46 41.24
69 INT3252 Negative_regulation of INS 1 428 0.59 271.65 39.52
70 INT9094 Gene_expression of COL7A1 1 277 0.77 143.42 38.73
71 INT1354 Negative_regulation of Acot1 1 87 0.43 15.01 36.44
72 INT14559 Gene_expression of Igf1 7 254 0.78 112 34.17
73 INT4403 Binding of CYP2B6 1 113 0.48 21.17 33.83
74 INT6302 Binding of IFNA1 1 196 0.48 133.85 32.73
75 INT9658 Negative_regulation of Gene_expression of Il6 1 110 0.59 66.29 32.58
76 INT13897 Localization of Sst 3 65 0.81 14.91 32.24
77 INT114881 Gene_expression of Akt1 1 227 0.78 102.49 31.81
78 INT7538 Negative_regulation of IL2 1 95 0.57 47.31 31.7
79 INT48693 Regulation of VEGFA 2 268 0.62 191.88 31.52
80 INT34729 Positive_regulation of IFN1@ 1 233 0.67 128.04 30.38
81 INT77652 Negative_regulation of Gene_expression of IL8 3 99 0.59 67.57 30.21
82 INT65597 Negative_regulation of Casp3 1 69 0.59 39.19 29.32
83 INT69157 Gene_expression of IL5 1 127 0.77 102.58 26.81
84 INT3760 Positive_regulation of ALB 1 142 0.70 87.46 26.7
85 INT16428 Positive_regulation of Gtf3a 1 135 0.20 106.44 26.67
86 INT79395 Gene_expression of Twist1 1 193 0.77 100.06 26.34
87 INT86062 Positive_regulation of Tnfrsf1a 1 51 0.69 40.69 26.2
88 INT62710 Gene_expression of HGF 4 160 0.78 88.27 26.14
89 INT122570 Negative_regulation of Akt1 1 173 0.59 91.44 25.53
90 INT48235 Negative_regulation of NPEPPS 5 72 0.46 44.54 25.03
91 INT55583 Localization of IFNA1 1 135 0.78 85.07 24.13
92 INT14556 Positive_regulation of Igf1 6 105 0.69 52.21 24.04
93 INT8775 Binding of IGHE 1 167 0.48 102.61 23.54
94 INT7113 Negative_regulation of Localization of CGA 1 71 0.51 17.7 23.42
95 INT100026 Gene_expression of Tnfrsf1b 10 73 0.72 43.26 23.23
96 INT14506 Regulation of Sst 2 46 0.62 15.02 22.66
97 INT14733 Positive_regulation of Gene_expression of TGFB1 1 71 0.69 49.89 22.2
98 INT8483 Positive_regulation of Positive_regulation of TNF 1 73 0.67 60.35 22.03
99 INT48692 Binding of VEGFA 3 345 0.48 210.3 21.31
100 INT78694 Positive_regulation of Gene_expression of Casp3 1 46 0.66 18.64 19.62
101 INT2006 Gene_expression of fc 1 104 0.34 64.91 19.08
102 INT192409 Positive_regulation of Gene_expression of IFN1@ 1 102 0.67 64.66 18.8
103 INT13454 Positive_regulation of Positive_regulation of Gh 1 49 0.68 14.53 18.49
104 INT71680 Gene_expression of CCL3 1 43 0.75 33.7 18.01
105 INT50579 Binding of CYP3A4 1 84 0.48 17.52 17.45
106 INT3656 Positive_regulation of Gene_expression of Ins1 1 74 0.54 44.94 17.36
107 INT36054 Transcription of IL1B 1 53 0.72 32.64 17.31
108 INT3206 Positive_regulation of Got1 1 39 0.69 19.36 17.02
109 INT10841 Positive_regulation of Gene_expression of Gh 4 101 0.59 45.39 16.96
110 INT13510 Gene_expression of ERBB2 1 530 0.78 405.68 16.79
111 INT109929 Phosphorylation of MAPK8 1 102 0.81 39.98 16.54
112 INT6110 Negative_regulation of Gene_expression of Ins1 3 83 0.56 60.59 16.07
113 INT170335 Gene_expression of INCENP 2 176 0.54 91.62 15.31
114 INT5333 Gene_expression of NPEPPS 1 45 0.65 26.34 15.25
115 INT1850 Binding of OXA1L 2 77 0.48 7.61 15.22
116 INT106745 Localization of CRP 1 65 0.81 66.44 15.21
117 INT19963 Gene_expression of COL1A1 1 118 0.59 42.11 15.15
118 INT24670 Gene_expression of FGF2 1 121 0.78 85.64 15.12
119 INT34590 Gene_expression of ALPP 1 199 0.75 89.85 15.1
120 INT109535 Gene_expression of Vegfa 2 116 0.75 84.61 14.89
121 INT105387 Gene_expression of HIF1A 4 116 0.77 98.62 14.66
122 INT65263 Positive_regulation of Gene_expression of Igf1 1 61 0.69 25.69 14.49
123 INT25076 Negative_regulation of Gene_expression of Il1 1 41 0.52 30.58 13.85
124 INT18773 Localization of ALB 3 117 0.80 69.18 13.8
125 INT18012 Gene_expression of EPO 6 169 0.78 108.36 13.75
126 INT18012 Gene_expression of EPO 3 169 0.78 108.36 13.75
127 INT6478 Negative_regulation of Binding of TNF 1 36 0.58 30.42 13.31
128 INT105670 Gene_expression of AAVS1 1 131 0.75 49.24 12.95
129 INT2578 Binding of Ins1 7 74 0.48 33.57 12.92
130 INT174838 Localization of INCENP 1 80 0.64 19.05 12.89
131 INT174838 Localization of INCENP 3 80 0.64 19.05 12.89
132 INT10870 Regulation of IgG 1 67 0.59 43.27 12.74
133 INT51014 Transcription of IL2 1 42 0.71 21.56 12.7
134 INT27268 Localization of Gtf3a 1 71 0.21 56.93 12.51
135 INT11244 Transcription of CALCA 1 21 0.69 3.61 12.27
136 INT159127 Gene_expression of Nps 5 49 0.75 16.91 12.06
137 INT61946 Positive_regulation of HGF 1 57 0.69 38.93 11.99
138 INT145281 Gene_expression of hb 4 89 0.59 63.22 11.96
139 INT126743 Positive_regulation of Gene_expression of LEP 1 61 0.66 50.02 11.17
140 INT13240 Gene_expression of TF 1 94 0.76 57.81 10.99
141 INT79656 Positive_regulation of NR3C1 1 14 0.68 6.38 10.83
142 INT51265 Phosphorylation of TNF 1 32 0.81 25.33 10.75
143 INT15350 Localization of Prl 1 22 0.81 6.86 10.74
144 INT3851 Gene_expression of Got1 2 58 0.65 29.15 10.52
145 INT78695 Regulation of Casp3 1 24 0.44 9.43 10.48
146 INT86464 Binding of LMOD1 2 31 0.44 10.23 10.46
147 INT100379 Positive_regulation of HIF1A 4 69 0.69 57.31 10.4
148 INT81929 Negative_regulation of Gene_expression of IL10 1 41 0.57 27.99 9.87
149 INT75137 Regulation of Akt1 1 74 0.48 37.89 9.7
150 INT62166 Positive_regulation of Gene_expression of Gpt 1 64 0.50 39.13 9.69
151 INT11510 Negative_regulation of Positive_regulation of Gh 2 28 0.52 12.71 9.16
152 INT22285 Negative_regulation of Mtx1 1 16 0.49 7.84 8.98
153 INT8903 Gene_expression of IFNA2 6 58 0.71 38.23 8.68
154 INT939 Gene_expression of PAEP 1 86 0.77 31.02 8.59
155 INT20205 Binding of IgG 1 108 0.46 66.68 8.57
156 INT43820 Positive_regulation of Twist1 1 75 0.59 42.15 8.47
157 INT61628 Negative_regulation of Gene_expression of IL4 2 31 0.55 20.96 8.18
158 INT60034 Positive_regulation of VWF 1 40 0.68 30.42 8.15
159 INT39170 Gene_expression of TSPO 1 76 0.78 24.11 8.05
160 INT75932 Binding of Csf2 1 45 0.37 33.2 8.01
161 INT2271 Gene_expression of F2 2 51 0.76 30.21 7.97
162 INT1499 Negative_regulation of Gene_expression of Gh 1 58 0.42 25.17 7.86
163 INT106522 Negative_regulation of Phosphorylation of Akt1 2 65 0.58 34.44 7.83
164 INT78320 Gene_expression of EPCAM 2 57 0.75 50.34 7.53
165 INT103154 Gene_expression of FLT1 1 138 0.76 58.5 7.41
166 INT63057 Regulation of CYP3A4 1 31 0.61 5.75 6.92
167 INT142344 Transcription of Igf1 1 22 0.69 7.55 6.77
168 INT10785 Gene_expression of Prl 1 35 0.78 20.64 6.7
169 INT211701 Positive_regulation of Mri1 2 20 0.34 20.64 6.69
170 INT74944 Positive_regulation of Gene_expression of HGF 1 31 0.70 17.69 6.68
171 INT15872 Positive_regulation of EPO 1 74 0.70 45.35 6.67
172 INT15872 Positive_regulation of EPO 1 74 0.70 45.35 6.67
173 INT25022 Binding of PAEP 5 66 0.42 22.83 6.59
174 INT74865 Gene_expression of Igh-Dex 4 16 0.22 8.95 6.59
175 INT5871 Binding of IFNA2 6 38 0.48 20.35 6.46
176 INT48239 Binding of Gtf3a 1 52 0.33 23.14 6.45
177 INT173967 Gene_expression of Mri1 2 26 0.43 16.67 6.45
178 INT166707 Protein_catabolism of Col7a1 1 24 0.74 20.47 6.39
179 INT28861 Binding of Gh 9 61 0.46 25.61 6.38
180 INT86805 Localization of HGF 5 49 0.71 28.48 6.35
181 INT128587 Localization of Mapk14 1 15 0.81 8.41 6.1
182 INT22128 Positive_regulation of HIVEP1 1 61 0.43 70.52 6.07
183 INT8803 Gene_expression of IL3 1 32 0.78 21.06 6.01
184 INT38686 Binding of NR3C1 2 20 0.48 9.25 5.99
185 INT52749 Gene_expression of alp 3 24 0.44 12.84 5.97
186 INT15132 Gene_expression of TNFRSF1A 3 33 0.75 20.09 5.93
187 INT53196 Binding of Cd4 1 44 0.47 27.28 5.85
188 INT63772 Gene_expression of LMOD1 7 26 0.75 3.77 5.84
189 INT13857 Binding of Sst 2 11 0.24 2.48 5.76
190 INT151032 Localization of Igf1 1 49 0.76 26.32 5.71
191 INT103260 Positive_regulation of Nps 1 35 0.48 23.8 5.67
192 INT17425 Regulation of Gene_expression of Ins1 1 23 0.45 18.99 5.61
193 INT105538 Negative_regulation of Tnfrsf1a 1 16 0.56 12.51 5.61
194 INT22839 Gene_expression of F2 2 31 0.74 15.53 5.56
195 INT22943 Positive_regulation of Positive_regulation of Gpt 1 23 0.47 16.09 5.55
196 INT124976 Positive_regulation of Tnfrsf1b 1 15 0.67 14.92 5.15
197 INT2579 Protein_catabolism of Ins1 3 43 0.99 9.91 5.14
198 INT5297 Regulation of IFNA2 1 20 0.56 10.81 5.13
199 INT20650 Positive_regulation of F2 1 26 0.69 15.49 5.08
200 INT60252 Binding of HIVEP1 1 59 0.32 65.12 5.06
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox