J:J. Chem. Neuroanat.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT34444 Binding of Oprl1 and Ptprg 4 2 0.03 0.18 4.58
2 INT101926 Binding of Dio1 and Drd2 4 1 0.28 0.39 1.66
3 INT64628 Binding of Oxt and Gal 2 1 0.29 0.29 1.49
4 INT52955 Binding of Slc6a3 and Pdpn 1 2 0.17 1.11 1.22
5 INT90050 Binding of GRP and Penk 1 1 0.06 0 1.06
6 INT111504 Pnoc Positive_regulation of Binding of Ptprg 1 2 0.01 0 0.96
7 INT64629 Binding of Gal and Crh 1 1 0.18 0.1 0.83
8 INT64627 Binding of Oxt and Crh 1 1 0.07 0.1 0.83
9 INT151339 Positive_regulation of Binding of Drd2 and P9Ehs1 1 1 0.11 0.22 0.76
10 INT151340 Binding of Drd2 and P9Ehs1 1 1 0.09 0.22 0.75
11 INT111506 Negative_regulation of Binding of Oprl1 and Ptprg 1 1 0.01 0 0.71
12 INT111505 Positive_regulation of Binding of Oprl1 and Ptprg 1 1 0.01 0 0.71
13 INT56700 Penk Regulation of FER 1 1 0.00 0 0.59
14 INT151338 Binding of Dio1 and P9Ehs1 1 1 0.09 0.16 0.52
15 INT111509 Pnoc Positive_regulation of Binding of Ptprg 1 1 0.00 0 0.47
16 INT146274 Binding of Rasd1 and Nos1ap 1 2 0.33 0.18 0.41
17 INT146273 Binding of Nos1 and Rasd1 1 2 0.34 0.18 0.41
18 INT52954 Binding of Pdpn and Flvcr2 1 1 0.05 0.42 0.41
19 INT146272 Binding of Nos1 and Nos1ap 1 2 0.28 0.2 0.39
20 INT146271 Nos1ap Positive_regulation of Positive_regulation of Rasd1 1 1 0.34 0.08 0.21

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT796 Gene_expression of Penk 4 1902 0.78 275.47 1057.59
2 INT3439 Localization of Abat 1 1017 0.78 112.39 727.06
3 INT292 Localization of Penk 7 876 0.81 88.44 669.14
4 INT728 Positive_regulation of Penk 5 1068 0.70 186.9 636.87
5 INT2543 Positive_regulation of Calca 2 787 0.70 331.13 592.08
6 INT5228 Positive_regulation of Fos 2 934 0.70 209.8 503.87
7 INT1395 Negative_regulation of Penk 4 537 0.59 87.33 389.81
8 INT2540 Negative_regulation of Calca 1 538 0.59 172.11 384.38
9 INT720 Positive_regulation of POMC 1 807 0.70 237.37 353.83
10 INT5660 Binding of Oprd1 2 477 0.48 71.86 342.06
11 INT16260 Gene_expression of Bdnf 1 671 0.78 283.44 339.1
12 INT2649 Regulation of Calca 2 433 0.62 146.05 330.95
13 INT5979 Gene_expression of Oprd1 3 428 0.78 75.64 320.32
14 INT5379 Gene_expression of Fos 1 656 0.78 255.5 292.54
15 INT1396 Binding of Penk 2 355 0.48 22.79 269.65
16 INT738 Regulation of POMC 1 459 0.62 111.19 243.74
17 INT1902 Gene_expression of Cck 1 348 0.78 70.33 241.92
18 INT9987 Gene_expression of Abat 1 296 0.78 95.46 226.34
19 INT1212 Binding of Oprl1 4 312 0.48 28.6 225.15
20 INT626 Localization of CALCA 1 289 0.81 125.39 221.15
21 INT6665 Gene_expression of FOS 4 520 0.77 165.31 217.66
22 INT6293 Gene_expression of Oprm1 1 312 0.78 48.73 215.61
23 INT4893 Gene_expression of Tacr1 1 366 0.78 129.67 213.92
24 INT48955 Gene_expression of Nos2 5 753 0.78 403.87 208.08
25 INT798 Positive_regulation of Gene_expression of Penk 1 394 0.70 78.53 203.07
26 INT943 Negative_regulation of Cck 1 205 0.59 38.42 174.78
27 INT21185 Binding of Ptprg 4 213 0.47 13.49 157.75
28 INT768 Positive_regulation of Oprl1 1 179 0.70 40.05 156.93
29 INT6042 Binding of Oprm1 1 248 0.48 31.77 154.34
30 INT4740 Gene_expression of Th 2 298 0.78 61.27 154.03
31 INT2910 Regulation of Abat 1 169 0.62 36.95 153.53
32 INT1273 Gene_expression of Avp 1 356 0.78 90.56 138.7
33 INT1614 Gene_expression of Oprl1 1 164 0.78 31.43 127.74
34 INT5008 Localization of Calca 2 204 0.81 80.35 125.16
35 INT5010 Gene_expression of Calca 1 197 0.78 85.76 118.75
36 INT16253 Positive_regulation of Gene_expression of Bdnf 1 196 0.70 92.67 113.01
37 INT47243 Gene_expression of Prkcg 1 195 0.78 58.05 108.44
38 INT12569 Localization of Oprd1 1 94 0.81 23.81 104.56
39 INT5940 Negative_regulation of Avp 6 236 0.59 67.86 101.2
40 INT5587 Regulation of Fos 1 191 0.62 40.81 99.7
41 INT7944 Positive_regulation of Fos 2 193 0.70 60.69 98.31
42 INT17459 Positive_regulation of Gene_expression of FOS 1 182 0.67 53.45 96.38
43 INT74058 Gene_expression of Nos1 1 260 0.78 80.04 95.71
44 INT1004 Regulation of Sst 1 140 0.62 18.52 94.84
45 INT29971 Gene_expression of Oprk1 2 126 0.78 35.32 93.97
46 INT18032 Positive_regulation of Oprk1 1 108 0.70 30.78 89.7
47 INT5610 Positive_regulation of Insr 4 140 0.69 37.26 86.24
48 INT5780 Regulation of Gene_expression of Calca 3 90 0.62 59.52 85.03
49 INT8650 Gene_expression of Gal 3 152 0.78 61.97 81.72
50 INT64636 Positive_regulation of Gene_expression of Nos2 1 242 0.70 147.52 79.53
51 INT24958 Gene_expression of Nkx1-1 1 106 0.74 51.29 76.88
52 INT1080 Negative_regulation of Ache 1 343 0.59 108.51 72.4
53 INT7872 Positive_regulation of P9Ehs1 1 74 0.50 18.54 66.16
54 INT66531 Gene_expression of Pnoc 2 88 0.78 22.9 65.11
55 INT6926 Regulation of Pag1 2 72 0.39 55.79 65.09
56 INT217 Negative_regulation of Th 1 134 0.59 26.83 62.63
57 INT8363 Localization of Nts 1 135 0.81 14.29 61.71
58 INT66779 Binding of Pnoc 1 79 0.48 6.43 60.46
59 INT62960 Gene_expression of P2rx2 2 149 0.77 58.31 59.16
60 INT6436 Positive_regulation of Positive_regulation of Fos 1 101 0.70 18.71 57.96
61 INT5017 Negative_regulation of Tacr1 1 76 0.58 17 57.07
62 INT5356 Positive_regulation of FOS 1 153 0.69 54.21 56.74
63 INT1510 Binding of PDYN 1 94 0.48 4.68 56.44
64 INT17458 Negative_regulation of Gene_expression of FOS 2 98 0.57 36.77 55.69
65 INT6826 Transcription of Pdyn 1 130 0.71 22.19 54.88
66 INT5034 Negative_regulation of Insr 2 100 0.55 28.08 54.5
67 INT6116 Regulation of Gene_expression of Oprd1 2 69 0.62 16.43 54
68 INT771 Regulation of Nts 1 93 0.61 13.13 53.57
69 INT10668 Positive_regulation of Gene_expression of Oprd1 2 61 0.69 15.21 52.12
70 INT49028 Positive_regulation of Nos1 1 102 0.70 34.73 51.05
71 INT6165 Gene_expression of Adarb1 2 85 0.58 18.39 51.03
72 INT49520 Gene_expression of P2rx3 3 121 0.78 61.15 49.24
73 INT51163 Gene_expression of Gal 6 119 0.78 67.48 49.23
74 INT17915 Gene_expression of Insr 18 141 0.75 47.45 48.59
75 INT12471 Regulation of Insrr 1 52 0.35 17.8 48.31
76 INT5337 Negative_regulation of Npy 3 87 0.59 19.6 46.75
77 INT8713 Regulation of Tac1 1 56 0.60 25.29 45.94
78 INT11854 Gene_expression of Il1rl1 1 57 0.77 30.19 38.25
79 INT5039 Positive_regulation of Gal 1 67 0.68 27.97 37.36
80 INT4843 Gene_expression of Npff 3 50 0.78 12.92 36.37
81 INT13501 Binding of Drd2 1 65 0.48 23.76 35.6
82 INT7675 Gene_expression of ENG 1 146 0.77 45.35 34.6
83 INT8746 Negative_regulation of Calca 2 50 0.59 21.22 33.45
84 INT14497 Gene_expression of GRP 1 82 0.78 17.67 32.27
85 INT9796 Gene_expression of Cck 1 63 0.78 11.44 32.09
86 INT29477 Transcription of Oprl1 2 52 0.72 5.05 30.52
87 INT5300 Regulation of Insr 1 54 0.60 11.33 29.26
88 INT15000 Transcription of Oprd1 1 32 0.72 5.7 29.22
89 INT1616 Regulation of Gad1 1 46 0.61 10.2 28.64
90 INT6594 Gene_expression of HTR1D 1 60 0.75 10.15 27.13
91 INT7832 Localization of Cck 1 39 0.81 6.81 26.54
92 INT79395 Gene_expression of Twist1 2 193 0.77 100.06 26.34
93 INT63444 Regulation of Gene_expression of Abat 1 26 0.51 14.65 26.29
94 INT48979 Regulation of Gene_expression of FOS 1 52 0.61 14.4 25.95
95 INT79979 Gene_expression of Ret 4 94 0.75 19.21 25.51
96 INT7584 Gene_expression of Crh 1 112 0.78 39.15 25.33
97 INT74688 Regulation of Nos1 4 55 0.62 22.16 25.3
98 INT57874 Gene_expression of Egr1 1 113 0.78 68.46 24.95
99 INT9155 Gene_expression of Glul 1 60 0.77 17.97 23.95
100 INT12475 Gene_expression of OPRL1 6 35 0.77 3.63 23.11
101 INT1156 Binding of CCK 1 27 0.48 8.71 20.58
102 INT4841 Localization of Npff 1 26 0.80 4.36 19.91
103 INT8075 Localization of Crh 1 64 0.81 25.41 19.45
104 INT48006 Negative_regulation of Oprk1 2 27 0.58 10.14 19.11
105 INT107930 Gene_expression of Slc17a7 1 39 0.78 6.53 18.86
106 INT14306 Positive_regulation of Gal 1 36 0.70 21.66 18.51
107 INT11275 Regulation of Fos 1 37 0.60 5.79 18.18
108 INT82531 Positive_regulation of Gene_expression of Gal 4 41 0.69 28.67 18.04
109 INT6461 Gene_expression of Npr1 1 35 0.75 10.38 17.58
110 INT9780 Regulation of Penk 1 30 0.60 6.78 17.19
111 INT107928 Gene_expression of Slc17a6 1 34 0.76 3.76 16.64
112 INT59365 Gene_expression of HTR1A 1 41 0.75 16.31 16.57
113 INT8530 Transcription of Penk 1 48 0.70 11.67 16.34
114 INT50618 Gene_expression of Dio1 1 48 0.74 17.37 15.91
115 INT1416 Transcription of POMC 1 40 0.72 10.71 15.38
116 INT4851 Positive_regulation of Chat 1 53 0.70 9.21 15.11
117 INT11945 Regulation of Chat 1 38 0.62 7.75 14.97
118 INT4053 Regulation of GRP 1 27 0.58 5.57 13.76
119 INT4842 Regulation of Npff 1 13 0.54 4.59 13.62
120 INT6749 Binding of Dio1 2 25 0.38 4.41 13.07
121 INT27507 Positive_regulation of Dio1 1 23 0.44 3.43 12.11
122 INT61706 Regulation of Gene_expression of Gal 2 17 0.62 10.09 11.96
123 INT14420 Regulation of Nka1 1 12 0.45 3.82 11.33
124 INT10874 Negative_regulation of Twist1 3 89 0.50 36.84 11.32
125 INT93967 Binding of Slc6a3 1 22 0.48 6.81 10.74
126 INT65009 Gene_expression of HTR3A 1 29 0.75 8.51 10.59
127 INT41627 Gene_expression of Nqo1 2 33 0.65 4.58 10.48
128 INT94859 Negative_regulation of Pde5a 2 67 0.43 33.66 10.28
129 INT17592 Positive_regulation of Regulation of Fos 1 21 0.67 3.54 10.07
130 INT12367 Binding of PRLR 3 17 0.03 2.05 9.69
131 INT8527 Positive_regulation of Positive_regulation of Fos 1 20 0.70 6.87 9.62
132 INT58841 Gene_expression of HTR2A 1 33 0.75 9.01 9.07
133 INT38173 Gene_expression of Ang 1 40 0.75 32.63 8.86
134 INT12663 Localization of Nkx1-1 1 16 0.74 3.77 8.74
135 INT15308 Localization of Chat 2 29 0.81 2.35 8.47
136 INT79406 Negative_regulation of Pde4a 1 20 0.59 25.26 8.35
137 INT30920 Positive_regulation of Gene_expression of Insr 2 14 0.66 2.91 7.32
138 INT56285 Localization of SCG2 1 10 0.81 1.65 6.92
139 INT91351 Gene_expression of P2rx1 3 28 0.75 5.89 6.78
140 INT8529 Regulation of Transcription of Penk 1 8 0.39 1.26 5.89
141 INT97265 Gene_expression of Npffr2 1 8 0.56 2.54 5.72
142 INT92280 Transcription of OPRL1 4 10 0.70 1.36 5.68
143 INT103260 Positive_regulation of Nps 1 35 0.48 23.8 5.67
144 INT133638 Gene_expression of Dbh 2 9 0.78 1.23 5.46
145 INT44997 Positive_regulation of Eef1a2 2 16 0.40 8.84 5.37
146 INT94028 Regulation of Twist1 1 37 0.44 22.41 5.33
147 INT52952 Binding of Pdpn 4 8 0.13 3.57 4.79
148 INT53442 Gene_expression of Npff 1 12 0.76 0.57 4.75
149 INT48960 Gene_expression of SCG2 3 16 0.68 4.41 4.33
150 INT88733 Gene_expression of NPFFR2 2 6 0.77 1.33 4.29
151 INT51084 Binding of Insr 1 13 0.30 4.25 4.23
152 INT57145 Transcription of OPRD1 1 6 0.61 0.34 2.99
153 INT53150 Gene_expression of Scg2 2 3 0.74 0.18 2.86
154 INT18059 Binding of GRIN2A 1 4 0.36 1.53 2.72
155 INT118374 Negative_regulation of Npff 1 2 0.42 0.59 2.56
156 INT147304 Gene_expression of Frzb 7 1 0.67 0 2.45
157 INT23121 Transcription of GRP 1 4 0.67 1.06 2.38
158 INT99451 Transcription of ELSPBP1 3 1 0.21 0.68 2.31
159 INT26434 Localization of MME 1 17 0.81 8.67 2.3
160 INT36642 Negative_regulation of Pde1a 1 4 0.43 0.89 2.15
161 INT24909 Negative_regulation of Pde10a 1 4 0.43 0.87 1.87
162 INT111511 Localization of Npffr2 2 1 0.66 0.37 1.84
163 INT147298 Transcription of Frzb 4 1 0.53 0 1.63
164 INT1580 Negative_regulation of Pde2a 1 7 0.52 3.26 1.59
165 INT99450 Regulation of Gene_expression of OPRL1 2 1 0.40 0.43 1.55
166 INT103272 Positive_regulation of Gene_expression of Dio1 1 4 0.26 1.66 1.34
167 INT111510 Positive_regulation of Gene_expression of Npffr2 1 2 0.36 0.27 1.28
168 INT34734 Binding of DSG3 1 4 0.48 2.91 1.17
169 INT7834 Gene_expression of Pde2a 1 5 0.51 1.9 1.01
170 INT62978 Negative_regulation of Trafd1 1 1 0.21 0.07 0.98
171 INT147302 Gene_expression of Fstl1 3 1 0.26 0 0.94
172 INT151336 Regulation of Binding of Dio1 1 2 0.30 0.2 0.9
173 INT135052 Negative_regulation of Positive_regulation of Pde9a 2 1 0.04 0.14 0.87
174 INT146261 Regulation of Rasd1 4 1 0.35 0.33 0.84
175 INT64635 Binding of Ifng 1 2 0.36 0.57 0.81
176 INT27509 Regulation of Frzb 1 3 0.61 0 0.75
177 INT52951 Negative_regulation of Binding of Pdpn 1 1 0.16 0.63 0.66
178 INT23012 Negative_regulation of Nrp1 3 4 0.35 0.69 0.63
179 INT146258 Regulation of Nos1ap 3 1 0.39 0.24 0.63
180 INT90049 Binding of Dio1 1 1 0.00 0 0.56
181 INT128460 Gene_expression of Nos1ap 2 2 0.59 0.32 0.54
182 INT134394 Positive_regulation of Positive_regulation of Gal 1 1 0.38 0.46 0.49
183 INT146255 Positive_regulation of Rasd1 2 1 0.39 0.22 0.48
184 INT134393 Regulation of Dbh 1 1 0.44 0.44 0.46
185 INT147297 Negative_regulation of Frzb 1 1 0.19 0 0.43
186 INT147299 Negative_regulation of Transcription of Frzb 1 1 0.43 0 0.43
187 INT147300 Negative_regulation of Gene_expression of Frzb 1 1 0.43 0 0.43
188 INT135053 Positive_regulation of Pde9a 1 1 0.05 0.06 0.42
189 INT147303 Regulation of Gene_expression of Frzb 1 1 0.45 0 0.41
190 INT146259 Binding of Nos1ap 2 1 0.32 0.2 0.39
191 INT147301 Positive_regulation of Gene_expression of Frzb 1 1 0.50 0 0.35
192 INT146268 Negative_regulation of Rasd1 1 1 0.33 0.15 0.27
193 INT146265 Positive_regulation of Gene_expression of Rasd1 1 1 0.37 0.14 0.27
194 INT146267 Positive_regulation of Nos1ap 1 1 0.43 0.14 0.27
195 INT146264 Negative_regulation of Nos1ap 1 1 0.37 0.15 0.27
196 INT146260 Gene_expression of Rasd1 1 1 0.61 0.14 0.26
197 INT103274 Regulation of SEC14L2 1 2 0.23 0.98 0.19
198 INT135054 Negative_regulation of Negative_regulation of Twist1 1 2 0.42 0.46 0.17
199 INT146270 Positive_regulation of Gene_expression of Nos1ap 1 1 0.35 0.08 0.13
200 INT92634 Negative_regulation of Binding of Insr 1 1 0.25 0.08 0.12
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