J:J. Clin. Endocrinol. Metab.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT26468 Ghrh Positive_regulation of Localization of Gh 21 3 0.37 3.26 9.21
2 INT1390 Trh Positive_regulation of Prl 14 2 0.67 4.42 4.39
3 INT1392 Trh Regulation of Prl 15 2 0.29 2.47 4.29
4 INT16221 Ghrh Positive_regulation of Gh 8 1 0.21 1.89 4.08
5 INT13729 GHRH Positive_regulation of Localization of GH1 13 3 0.62 0.59 3.2
6 INT31513 Crh Regulation of POMC 3 1 0.29 5.06 2.78
7 INT9180 Ghrh Regulation of Localization of Gh 3 1 0.24 0.25 2.18
8 INT13940 DNM2 Regulation of Localization of CGA 1 3 0.11 0 1.86
9 INT16891 GHRH Regulation of GH1 5 2 0.37 1.94 1.82
10 INT12691 SST Negative_regulation of Localization of POMC 3 2 0.24 1.24 1.45
11 INT52568 HTR1D Regulation of Localization of Gh 2 1 0.20 0.16 1.34
12 INT40900 PDYN Regulation of Localization of POMC 2 1 0.07 0.56 1.22
13 INT25026 PLOD1 Regulation of FSHR 4 1 0.19 0.38 1.15
14 INT25036 TRH Regulation of Prl 4 2 0.27 1.75 1.09
15 INT52562 Lhb Positive_regulation of Prl 3 1 0.00 1.09 1.02
16 INT33135 Binding of NFKBIL1 and PRL 1 1 0.09 0.29 1.01
17 INT35157 GH1 Regulation of GHRH 3 1 0.17 0.5 0.99
18 INT62106 Ghrh Negative_regulation of Localization of Gh 1 2 0.06 0 0.94
19 INT62109 SLC25A4 Negative_regulation of Localization of Gh 1 2 0.06 0 0.94
20 INT62111 SLC25A4 Negative_regulation of Regulation of Ghrh 1 2 0.41 0 0.9
21 INT44442 GNRH1 Positive_regulation of Localization of PLOD1 3 1 0.50 0.78 0.86
22 INT5451 CRH Regulation of POMC 2 1 0.28 0.39 0.85
23 INT34740 BID Regulation of Gene_expression of PLOD1 1 1 0.01 0 0.83
24 INT52557 Lhb Regulation of Trh Positive_regulation of Prl 1 1 0.00 0.14 0.83
25 INT46085 Binding of MET and Penk 1 1 0.02 0.06 0.83
26 INT46084 Binding of SELL and Penk 1 1 0.02 0.06 0.83
27 INT52571 Lhb Regulation of Lhb Positive_regulation of Prl 1 1 0.00 0.14 0.83
28 INT46076 Binding of MET and SELL 1 1 0.39 0.06 0.83
29 INT52558 Lhb Regulation of Trh Regulation of Prl 1 1 0.00 0.14 0.83
30 INT52573 Trh Regulation of Trh Regulation of Prl 1 1 0.00 0.14 0.82
31 INT2000 ASNA1 Positive_regulation of Localization of PRL 1 2 0.07 0 0.79
32 INT52561 Trh Positive_regulation of Localization of Lhb 1 1 0.01 0.14 0.77
33 INT40127 Lhb Regulation of Localization of PRL 1 1 0.20 0.41 0.75
34 INT40126 PRL Regulation of Localization of Lhb 1 1 0.20 0.41 0.75
35 INT16894 Regulation of GHRH Regulation of GH1 2 1 0.37 0 0.72
36 INT30125 Binding of Gh and Ghrh 2 1 0.06 0.36 0.7
37 INT34772 GH1 Regulation of IGF1 2 1 0.32 0.95 0.69
38 INT52570 HTR1D Negative_regulation of Localization of SST 1 1 0.46 0.07 0.67
39 INT45369 IGF1 Regulation of GH1 1 1 0.04 1.12 0.65
40 INT32722 Prl Regulation of Lhb 1 1 0.02 0 0.6
41 INT40901 Trf Regulation of Localization of POMC 1 1 0.07 0.56 0.6
42 INT84067 IGFBP1 Regulation of GH1 1 1 0.02 1.18 0.54
43 INT29252 Regulation of INS Positive_regulation of GH1 1 1 0.26 0.08 0.54
44 INT29255 INS Positive_regulation of INS Positive_regulation of GH1 1 1 0.47 0.08 0.53
45 INT19879 Regulation of GNRH1 Regulation of Lhb 1 1 0.05 0 0.53
46 INT29253 INS Positive_regulation of GH1 1 1 0.44 0.08 0.53
47 INT5132 GNRH1 Regulation of Lhb 2 1 0.08 0 0.52
48 INT46051 ABAT Regulation of Localization of GH1 1 1 0.19 0 0.49
49 INT20761 INHBA Regulation of Localization of GNRH1 1 1 0.02 0 0.46
50 INT46008 OPRM1 Regulation of Localization of PRL 1 1 0.14 0 0.44
51 INT29254 Positive_regulation of ADRA2C Positive_regulation of Localization of GH1 1 1 0.13 0.06 0.44
52 INT25027 CRH Negative_regulation of Negative_regulation of FSHR 1 1 0.25 0 0.42
53 INT62107 Ghrh Negative_regulation of Regulation of Gh 1 1 0.06 0 0.39
54 INT62110 SLC25A4 Negative_regulation of Regulation of Gh 1 1 0.06 0 0.39
55 INT45797 ZBTB7A Regulation of Lhb 1 1 0.36 0.09 0.38
56 INT45798 TRH Regulation of Lhb 1 1 0.36 0.09 0.38
57 INT43956 GCG Regulation of ALB 1 1 0.16 0.15 0.38
58 INT78444 Binding of GH1 and IGF1 4 2 0.16 2.82 0.37
59 INT16896 GHSR Regulation of GH1 2 1 0.23 0.24 0.36
60 INT35363 Binding of GH1 and GHRH 2 1 0.36 0.94 0.36
61 INT4382 RIPK2 Regulation of INS 1 1 0.12 0.58 0.36
62 INT16893 GHSR Positive_regulation of GH1 2 1 0.26 0.24 0.35
63 INT43388 OPRM1 Positive_regulation of Localization of PLOD1 1 1 0.27 0 0.34
64 INT4381 RIPK2 Positive_regulation of Localization of INS 1 1 0.13 0.53 0.34
65 INT17301 Binding of CGA and Lhb 1 1 0.00 0 0.33
66 INT107751 POMC Negative_regulation of HSD17B1 1 2 0.33 0.39 0.33
67 INT31182 Adra2a Regulation of Localization of Gh 1 1 0.01 0.35 0.32
68 INT26065 GHRH Regulation of Regulation of GH1 1 1 0.11 0 0.3
69 INT12390 AVP Regulation of Localization of POMC 1 1 0.29 0.27 0.3
70 INT107747 CRH Negative_regulation of HSD17B1 1 2 0.40 0.41 0.3
71 INT51275 IGF1 Negative_regulation of INS 2 2 0.35 0.98 0.29
72 INT25028 GNRH1 Positive_regulation of CGA 1 1 0.03 0 0.29
73 INT25025 Regulation of GNRH1 Positive_regulation of CGA 1 1 0.03 0 0.29
74 INT26175 POMC Positive_regulation of GCG 2 1 0.47 0.57 0.28
75 INT67768 NPL Positive_regulation of PLOD1 1 1 0.30 0 0.28
76 INT67769 Regulation of NPL Positive_regulation of PLOD1 1 1 0.17 0 0.28
77 INT33977 DIO2 Regulation of PCDHB17 1 1 0.00 0.44 0.27
78 INT103279 PGR Negative_regulation of Gene_expression of CCL5 1 1 0.32 0.31 0.27
79 INT103280 PGR Negative_regulation of Positive_regulation of ATF4 1 1 0.02 0.31 0.26
80 INT16895 Regulation of GHSR Regulation of GH1 1 1 0.23 0 0.26
81 INT47639 GH1 Positive_regulation of Prl 1 1 0.09 0.64 0.25
82 INT31466 Binding of SGCG and CALCRL 1 1 0.02 0 0.23
83 INT87750 IGFBP3 Negative_regulation of INS 1 1 0.11 0.86 0.23
84 INT34773 GH1 Regulation of IGF2 1 1 0.31 0.05 0.22
85 INT107749 IL1B Positive_regulation of HSD17B1 1 1 0.20 0.21 0.22
86 INT32395 POMC Positive_regulation of INS 1 1 0.41 0.52 0.19
87 INT55988 POMC Positive_regulation of Negative_regulation of Crh 1 1 0.01 0 0.18
88 INT45738 TRH Positive_regulation of TRH Regulation of Prl 2 1 0.51 0.61 0.17
89 INT107746 TNF Positive_regulation of HSD17B1 1 1 0.39 0.2 0.17
90 INT107750 CRH Regulation of Transcription of HSD17B1 1 1 0.19 0.21 0.17
91 INT107748 POMC Regulation of Transcription of HSD17B1 1 1 0.15 0.21 0.17
92 INT107745 POMC Regulation of Gene_expression of HSD17B1 1 1 0.25 0.21 0.17
93 INT59952 Gh Positive_regulation of IGF1 1 1 0.46 0.84 0.16
94 INT73076 IGF1 Positive_regulation of GH1 4 2 0.45 0.99 0.15
95 INT16892 GHSR Positive_regulation of Localization of GH1 1 1 0.36 0 0.15
96 INT74070 Trh Regulation of Lhb 1 1 0.02 0.27 0.15
97 INT16104 GNRH1 Positive_regulation of Lhb 2 1 0.03 0.53 0.14
98 INT68753 IGF1 Regulation of Gene_expression of Gh 2 2 0.02 0.68 0.13
99 INT78446 Binding of GH1 and IGFBP3 1 1 0.11 0.48 0.1
100 INT113724 Glp1r Regulation of MIA3 2 1 0.00 1.22 0.08
101 INT113723 Gip Regulation of MIA3 2 1 0.00 1.28 0.08
102 INT49363 Gh Positive_regulation of Igf1 1 1 0.00 0.49 0.08
103 INT49372 Gh Positive_regulation of Gene_expression of IGFBP3 1 1 0.00 0.51 0.08
104 INT70762 IGF1 Regulation of Gh 1 1 0.00 0.17 0.07
105 INT53857 Negative_regulation of Crh Positive_regulation of GNRH1 1 1 0.13 0.5 0.07
106 INT51273 IGF1 Positive_regulation of IGFBP2 1 1 0.37 0.13 0.06
107 INT25491 TFPI Regulation of Localization of ENG 1 1 0.27 0.31 0.06
108 INT78445 Binding of GHRH and IGF1 1 1 0.20 0.72 0.06
109 INT51276 IGF1 Negative_regulation of GH1 1 1 0.10 0.13 0.06
110 INT25490 Binding of ENG and TFPI 1 1 0.27 0.4 0.06
111 INT51274 IGF1 Negative_regulation of IGF2 1 1 0.28 0.13 0.06
112 INT44230 Negative_regulation of Binding of PLOD1 and TRH 1 1 0.19 0.9 0
113 INT44228 TRH Regulation of PLOD1 1 1 0.12 0.9 0
114 INT47482 PRL Regulation of Gene_expression of LGALS1 1 1 0.19 0 0
115 INT75319 IGF1 Positive_regulation of Gh 1 1 0.00 0.26 0
116 INT87748 IGF1 Positive_regulation of INS 1 1 0.41 0.17 0
117 INT44227 Binding of PLOD1 and TRH 1 1 0.17 0.9 0
118 INT44233 Binding of FSHR and TRH 1 1 0.34 0.9 0
119 INT16355 GH1 Positive_regulation of IGF1 1 1 0.24 0.25 0
120 INT6131 INSIG1 Positive_regulation of POMC 1 1 0.06 0.61 0
121 INT44232 FSHR Regulation of PLOD1 1 1 0.15 0.9 0
122 INT44229 TRH Regulation of FSHR 1 1 0.11 0.9 0
123 INT44231 Negative_regulation of Binding of FSHR and TRH 1 1 0.39 0.91 0
124 INT73079 TTF1 Positive_regulation of GH1 1 2 0.04 0.33 0
125 INT75318 Gh Regulation of Gene_expression of IGF1 1 1 0.00 0.26 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT796 Gene_expression of Penk 1 1902 0.78 275.47 1057.59
2 INT158 Localization of Prl 29 2431 0.81 378.96 952.2
3 INT155 Positive_regulation of Prl 20 1233 0.70 317.93 457.82
4 INT443 Localization of POMC 49 1020 0.81 284.52 443.17
5 INT467 Gene_expression of POMC 19 1048 0.78 332.8 394.16
6 INT157 Positive_regulation of Localization of Prl 11 790 0.70 104.54 374.78
7 INT439 Localization of Gnrh1 1 976 0.81 100.96 363.25
8 INT720 Positive_regulation of POMC 34 807 0.70 237.37 353.83
9 INT5059 Positive_regulation of TNF 1 1050 0.70 896.51 322.81
10 INT162 Regulation of Prl 40 794 0.62 165.01 322.24
11 INT4941 Positive_regulation of Oprd1 1 345 0.70 74.26 304.41
12 INT161 Regulation of Localization of Prl 7 615 0.62 65.37 298.66
13 INT1893 Localization of Gh 95 1041 0.79 340.23 256.58
14 INT5501 Regulation of Oprd1 1 283 0.62 55.1 249.9
15 INT738 Regulation of POMC 23 459 0.62 111.19 243.74
16 INT1562 Localization of Crh 3 499 0.81 126.74 236.68
17 INT1308 Localization of Pomc 2 457 0.81 66.83 217.5
18 INT767 Localization of Gnrhr 6 565 0.80 106.68 214.57
19 INT156 Negative_regulation of Prl 16 542 0.59 131.97 192.24
20 INT528 Gene_expression of Prl 20 693 0.78 217.18 192.2
21 INT1429 Gene_expression of PDYN 4 308 0.78 61.33 175.65
22 INT159 Negative_regulation of Localization of Prl 3 416 0.59 55.34 171.8
23 INT4937 Negative_regulation of Oprd1 4 224 0.59 44.51 171.11
24 INT438 Gene_expression of Crh 1 376 0.78 159.11 169.17
25 INT739 Negative_regulation of POMC 16 358 0.59 102.28 166.77
26 INT4768 Positive_regulation of OPRM1 1 212 0.70 31.09 164.28
27 INT5127 Localization of Lhb 72 488 0.80 50.48 162.66
28 INT3448 Positive_regulation of Gh 41 521 0.69 180.03 161.18
29 INT2640 Gene_expression of Pomc 1 424 0.78 120.72 155.37
30 INT2451 Positive_regulation of Avp 1 355 0.70 102.66 147.69
31 INT812 Localization of INS 10 1026 0.81 515.6 145.31
32 INT425 Localization of PRL 54 455 0.81 189.64 144.8
33 INT4658 Binding of OPRM1 1 188 0.48 25.96 136.24
34 INT1878 Binding of HLA-B 1 440 0.48 321.16 127.36
35 INT695 Binding of POMC 4 304 0.48 56.66 126.85
36 INT252 Localization of GH1 66 529 0.80 227.4 122.05
37 INT6128 Positive_regulation of Localization of POMC 13 256 0.70 68.77 121.64
38 INT7395 Localization of GNRH1 39 399 0.81 62.88 117.68
39 INT1438 Localization of Pomc 1 360 0.81 101.26 116.47
40 INT1793 Localization of CGA 35 379 0.81 67.38 114.69
41 INT1530 Regulation of Gh 44 382 0.61 115.96 112.47
42 INT3038 Gene_expression of INS 8 1583 0.78 1174.16 107.01
43 INT12569 Localization of Oprd1 2 94 0.81 23.81 104.56
44 INT915 Positive_regulation of PRL 26 342 0.70 141.96 104.31
45 INT1898 Regulation of Crh 1 220 0.62 61.33 102.64
46 INT397 Localization of SST 17 232 0.81 58.05 101.19
47 INT11587 Gene_expression of CSF2 3 645 0.78 544.38 93.89
48 INT5865 Positive_regulation of Localization of Gh 36 282 0.69 84.86 93.5
49 INT203 Positive_regulation of Pomc 4 257 0.70 90.56 92.84
50 INT2122 Negative_regulation of Localization of Gnrh1 1 226 0.59 26.92 92.04
51 INT214 Localization of AVP 13 370 0.81 208.51 91.09
52 INT1639 Negative_regulation of OPRM1 1 107 0.59 13.86 90.37
53 INT339 Regulation of Trh 1 156 0.62 39.27 83.55
54 INT1309 Positive_regulation of Localization of Gnrhr 3 152 0.69 24.25 81.56
55 INT403 Localization of Trh 1 241 0.81 28.55 81.45
56 INT1498 Gene_expression of Gh 32 521 0.75 220.84 81.16
57 INT7528 Regulation of OPRM1 2 100 0.62 20.63 80.57
58 INT920 Localization of PLOD1 39 223 0.81 42.25 78.7
59 INT1335 Negative_regulation of Oprl1 1 123 0.59 18.02 77.13
60 INT1497 Negative_regulation of Gh 34 415 0.59 192.95 74.71
61 INT442 Localization of PDYN 6 99 0.81 11.87 72.75
62 INT5128 Positive_regulation of Lhb 42 232 0.69 44.23 71.26
63 INT1377 Positive_regulation of Trh 2 172 0.70 40.55 69.83
64 INT2123 Positive_regulation of Gnrh1 1 209 0.70 24.2 68.97
65 INT462 Regulation of Pomc 3 157 0.62 41.67 67.27
66 INT253 Regulation of PRL 19 184 0.62 47.27 65.79
67 INT4960 Positive_regulation of CSF2 1 285 0.70 256.73 65.73
68 INT8347 Gene_expression of SST 1 181 0.78 104.59 65.45
69 INT2056 Negative_regulation of Gnrh1 1 175 0.59 33.43 63.32
70 INT217 Negative_regulation of Th 1 134 0.59 26.83 62.63
71 INT5095 Localization of Ghrh 6 185 0.81 28.09 62.08
72 INT12175 Positive_regulation of PDYN 1 86 0.69 18.27 62.04
73 INT1437 Negative_regulation of Pomc 2 132 0.59 35.22 60.97
74 INT1430 Regulation of PDYN 4 88 0.60 16.99 60.32
75 INT14740 Gene_expression of TGFB1 1 272 0.78 168.48 60.18
76 INT546 Binding of ALB 1 311 0.48 85.98 60.14
77 INT3161 Regulation of Localization of Gh 8 163 0.61 35.43 59.45
78 INT5016 Negative_regulation of Crh 5 129 0.59 36.74 59.28
79 INT1794 Regulation of Localization of CGA 11 136 0.57 13.39 59.07
80 INT5710 Negative_regulation of Localization of Lhb 30 146 0.57 20.51 58.33
81 INT770 Regulation of Localization of Gnrhr 2 127 0.61 17.91 58.23
82 INT1510 Binding of PDYN 1 94 0.48 4.68 56.44
83 INT5453 Regulation of Localization of POMC 10 114 0.62 20.56 56.34
84 INT1579 Gene_expression of PRL 17 279 0.78 119.2 55.41
85 INT78899 Gene_expression of CCL5 6 155 0.77 84.02 55.09
86 INT251 Regulation of INS 13 398 0.62 232.47 55.04
87 INT249 Localization of GHRH 20 215 0.80 78.02 51.87
88 INT5118 Regulation of SST 2 97 0.62 34.35 51.74
89 INT5136 Negative_regulation of PDYN 1 71 0.59 11.22 51.14
90 INT921 Regulation of GH1 22 172 0.60 52.88 51.04
91 INT1199 Positive_regulation of INS 6 579 0.70 399.64 50.43
92 INT2323 Gene_expression of Trh 1 146 0.78 29.92 49.5
93 INT6299 Regulation of Localization of Lhb 23 104 0.61 8.98 48.79
94 INT17881 Gene_expression of LEP 2 278 0.78 221.61 48.31
95 INT1197 Negative_regulation of Localization of POMC 8 109 0.59 28.29 48.02
96 INT1977 Negative_regulation of Positive_regulation of Prl 1 98 0.59 17.06 47.88
97 INT654 Localization of REN 1 250 0.81 75.12 47.86
98 INT375 Positive_regulation of REN 1 293 0.70 152.46 47.55
99 INT789 Positive_regulation of YY1 1 69 0.67 14.07 47.06
100 INT847 Regulation of Lhb 23 131 0.61 22.08 46.54
101 INT683 Positive_regulation of AVP 7 173 0.70 74.55 46.41
102 INT1322 Positive_regulation of Localization of INS 2 293 0.70 120.86 45.98
103 INT2262 Negative_regulation of Lhb 21 142 0.59 25.47 44.81
104 INT1894 Negative_regulation of Localization of Gh 17 168 0.58 64.12 43.56
105 INT5130 Regulation of GNRH1 14 139 0.62 31.95 42.08
106 INT3933 Positive_regulation of PLOD1 24 128 0.70 30.76 42.03
107 INT5454 Localization of CRH 7 124 0.79 79.18 41.53
108 INT957 Positive_regulation of GHRH 10 136 0.70 36.84 40.52
109 INT918 Positive_regulation of Localization of PRL 12 90 0.70 23.97 40.3
110 INT685 Regulation of AVP 5 124 0.62 34.9 39.91
111 INT3252 Negative_regulation of INS 5 428 0.59 271.65 39.52
112 INT1931 Positive_regulation of Gene_expression of POMC 2 116 0.70 37.26 38.67
113 INT1596 Negative_regulation of Oprl1 3 61 0.57 13.5 38.41
114 INT916 Regulation of Localization of PRL 16 92 0.62 22.98 38.13
115 INT5711 Positive_regulation of Localization of Lhb 13 90 0.70 10.92 36.76
116 INT3253 Negative_regulation of Localization of INS 4 205 0.59 130.39 36.61
117 INT1976 Regulation of Gene_expression of Prl 2 80 0.62 20.19 36
118 INT1361 Negative_regulation of Gnrhr 3 118 0.58 57.77 35.54
119 INT255 Regulation of Localization of GH1 16 89 0.62 18.71 35.3
120 INT3679 Gene_expression of AVP 4 171 0.78 72.9 35.23
121 INT326 Gene_expression of Gnrhr 1 105 0.76 35.87 34.93
122 INT7675 Gene_expression of ENG 2 146 0.77 45.35 34.6
123 INT692 Negative_regulation of SST 8 72 0.59 28.68 34.52
124 INT8905 Gene_expression of EDN1 11 215 0.78 157.1 34.19
125 INT11764 Positive_regulation of ENG 1 78 0.61 27.65 33.69
126 INT248 Positive_regulation of Localization of GH1 21 137 0.69 49.25 32.92
127 INT5868 Positive_regulation of GNRH1 12 122 0.69 20.96 32.8
128 INT913 Regulation of Localization of PLOD1 14 71 0.62 8.64 32.72
129 INT7692 Positive_regulation of PENK 1 71 0.70 20.34 32.54
130 INT8915 Gene_expression of Igf1 4 199 0.78 78.58 32.51
131 INT1495 Positive_regulation of Rtcd1 1 91 0.54 22.93 32.43
132 INT985 Negative_regulation of GH1 30 213 0.57 89.53 32.39
133 INT7396 Regulation of Localization of GNRH1 12 81 0.62 6.57 31.31
134 INT8531 Transcription of PDYN 2 56 0.72 19.51 30.99
135 INT7975 Regulation of PLOD1 12 97 0.62 20.9 30.51
136 INT7845 Regulation of OPRK1 1 44 0.62 4.54 30.49
137 INT5507 Regulation of Localization of Crh 1 57 0.61 8.43 30.26
138 INT5100 Positive_regulation of Ghrh 9 100 0.64 24.2 30.21
139 INT7397 Negative_regulation of Localization of GNRH1 12 86 0.59 15.45 29.78
140 INT1196 Positive_regulation of Positive_regulation of POMC 4 51 0.70 15.99 28.58
141 INT7035 Regulation of CGA 6 87 0.45 29.04 28.45
142 INT16879 Binding of Crh 2 72 0.48 21.65 28.43
143 INT22045 Gene_expression of IRF6 3 158 0.75 58.07 27.81
144 INT48202 Gene_expression of Tgfb1 1 146 0.78 89.93 27.76
145 INT5135 Negative_regulation of GNRH1 13 106 0.58 36.63 27.71
146 INT6174 Regulation of Gene_expression of POMC 1 49 0.61 9.75 27.69
147 INT10799 Localization of ENG 2 63 0.78 18.67 27.28
148 INT1638 Negative_regulation of PLOD1 18 92 0.59 21.69 26.61
149 INT9682 Positive_regulation of IGF1 14 238 0.70 120.03 26.36
150 INT2261 Gene_expression of Lhb 11 121 0.77 42.78 26.04
151 INT7394 Positive_regulation of Localization of GNRH1 13 67 0.69 7.22 25.29
152 INT2614 Gene_expression of CGA 4 187 0.78 105.89 24.77
153 INT2140 Regulation of REN 1 104 0.62 28.24 24.49
154 INT6441 Positive_regulation of CRH 7 98 0.69 57.22 24.12
155 INT5131 Gene_expression of GNRH1 4 109 0.78 28.79 23.94
156 INT682 Negative_regulation of AVP 4 97 0.59 50.67 23.91
157 INT71781 Phosphorylation of MAPK3 3 62 0.80 27.73 23.73
158 INT9292 Positive_regulation of SGCG 1 93 0.67 35.13 23.48
159 INT7113 Negative_regulation of Localization of CGA 10 71 0.51 17.7 23.42
160 INT2290 Protein_catabolism of POMC 1 41 0.99 4.86 23.36
161 INT250 Regulation of GHRH 5 65 0.61 17.46 23.19
162 INT956 Negative_regulation of PRL 6 94 0.59 42.72 23.01
163 INT917 Positive_regulation of Localization of PLOD1 13 51 0.69 8.53 22.87
164 INT3330 Gene_expression of AGT 1 149 0.76 98.65 22.73
165 INT4612 Positive_regulation of Localization of CGA 16 64 0.64 8.51 22.39
166 INT71047 Gene_expression of CYP19A1 1 122 0.78 68.78 22.21
167 INT16303 Negative_regulation of Localization of GH1 13 89 0.59 37.31 22.15
168 INT1327 Regulation of Localization of Trh 1 45 0.62 6.05 22.09
169 INT23257 Regulation of CRP 1 127 0.62 100.05 21.87
170 INT693 Negative_regulation of Localization of SST 9 46 0.59 8.57 21.75
171 INT1644 Regulation of FSHR 3 77 0.55 15.62 21.49
172 INT6127 Regulation of Localization of AVP 5 60 0.62 15.12 20.84
173 INT1792 Positive_regulation of CGA 6 123 0.70 64.73 20.79
174 INT955 Gene_expression of GHRH 4 126 0.78 59.91 20.74
175 INT1512 Binding of Prl 2 73 0.48 26.22 20.63
176 INT78901 Localization of CCL5 1 67 0.78 40.79 20.59
177 INT82434 Positive_regulation of LEP 1 117 0.70 95.45 20.22
178 INT160 Regulation of Positive_regulation of Prl 2 37 0.62 7.56 20.09
179 INT8662 Positive_regulation of EDN1 1 144 0.70 125.34 19.59
180 INT7364 Regulation of Ghrh 10 49 0.58 8.05 19.05
181 INT5372 Localization of LHB 4 55 0.68 9.47 19
182 INT28951 Negative_regulation of IGF1 19 133 0.59 75.77 18.9
183 INT11628 Regulation of Localization of Pomc 1 44 0.61 10.46 18.66
184 INT1975 Regulation of Regulation of Prl 4 32 0.59 5.78 18.53
185 INT13454 Positive_regulation of Positive_regulation of Gh 10 49 0.68 14.53 18.49
186 INT3952 Negative_regulation of ALB 2 116 0.59 72.18 18.35
187 INT14724 Negative_regulation of CYP19A1 2 233 0.59 96.56 18.26
188 INT9179 Positive_regulation of Localization of Ghrh 7 42 0.70 7.05 18.1
189 INT3118 Negative_regulation of Positive_regulation of POMC 4 33 0.59 9.42 18.07
190 INT1642 Negative_regulation of Localization of PLOD1 9 40 0.58 10.67 17.95
191 INT71787 Positive_regulation of MAPK3 1 37 0.67 17.5 17.88
192 INT871 Negative_regulation of Gene_expression of Prl 2 53 0.58 18.89 17.79
193 INT7414 Regulation of Localization of SST 3 31 0.60 4.85 17.46
194 INT22068 Binding of CALCRL 2 53 0.41 6.14 17.32
195 INT3364 Binding of SGCG 1 87 0.47 31.93 17.24
196 INT1578 Negative_regulation of Localization of PRL 6 52 0.59 20.62 17.18
197 INT10841 Positive_regulation of Gene_expression of Gh 6 101 0.59 45.39 16.96
198 INT213 Negative_regulation of Localization of AVP 3 46 0.59 19.78 16.79
199 INT6129 Positive_regulation of Localization of AVP 3 63 0.70 30.44 16.64
200 INT984 Positive_regulation of Localization of GHRH 8 58 0.70 12.66 16.51
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