J:J. Invest. Dermatol.

From wiki-pain
Jump to: navigation, search

This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT69872 Binding of MC1R and POMC 52 4 0.54 8.87 18.3
2 INT86637 POMC Regulation of Gene_expression of KRT16 2 2 0.47 1.22 1.61
3 INT86636 POMC Positive_regulation of Gene_expression of KRT16 2 2 0.39 0.83 1.28
4 INT107938 POMC Positive_regulation of Gene_expression of TGFBR2 1 1 0.42 1.09 1.07
5 INT69874 POMC Negative_regulation of TYRP1 1 2 0.13 0 1.07
6 INT69871 ASIP Negative_regulation of TYRP1 1 2 0.36 0 1.07
7 INT101381 POMC Regulation of Localization of IL8 1 2 0.28 1.49 1.02
8 INT69870 ASIP Negative_regulation of Binding of MC1R and POMC 1 2 0.37 0 0.9
9 INT107937 POMC Regulation of Gene_expression of TGFBR2 1 1 0.28 0.82 0.81
10 INT86638 POMC Negative_regulation of Gene_expression of OPRM1 1 1 0.34 0.33 0.68
11 INT97655 Binding of RBM25 and Mc1r 1 1 0.00 0.44 0.58
12 INT119281 Pnoc Regulation of Oprl1 1 1 0.31 0.29 0.56
13 INT69873 ASIP Negative_regulation of Binding of POMC 1 1 0.35 0 0.45
14 INT58969 TNF Regulation of Regulation of RPS6KA6 1 2 0.35 0.34 0.38
15 INT58967 TNF Regulation of RPS6KA6 1 2 0.18 0.33 0.38
16 INT69881 Positive_regulation of Gtf3a Positive_regulation of Gene_expression of TNF 1 1 0.03 0.6 0.31
17 INT101510 PPARA Regulation of IL6 1 1 0.31 0.53 0.27
18 INT101508 PPARA Regulation of IL8 1 1 0.31 0.53 0.27
19 INT101509 PPARA Regulation of Gene_expression of IL8 1 1 0.31 0.53 0.27
20 INT101511 PPARA Regulation of Gene_expression of IL6 1 1 0.31 0.53 0.27
21 INT38711 CYSLTR1 Positive_regulation of Gene_expression of PTGS1 1 1 0.08 0.14 0.25
22 INT86634 POMC Positive_regulation of TYR 2 1 0.42 0 0.24
23 INT58968 TNF Positive_regulation of Gene_expression of RPS6KA6 1 1 0.36 0.2 0.21
24 INT58966 TNF Regulation of TNF Regulation of RPS6KA6 1 1 0.19 0.17 0.19
25 INT58970 TNF Regulation of BHLHE23 1 1 0.28 0.17 0.19

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 10 3152 0.78 2515.62 929.82
2 INT1912 Gene_expression of Calca 1 1152 0.78 453.25 739.84
3 INT443 Localization of POMC 2 1020 0.81 284.52 443.17
4 INT9238 Gene_expression of IL6 2 1575 0.78 1135.66 424.22
5 INT467 Gene_expression of POMC 19 1048 0.78 332.8 394.16
6 INT2540 Negative_regulation of Calca 1 538 0.59 172.11 384.38
7 INT720 Positive_regulation of POMC 11 807 0.70 237.37 353.83
8 INT34869 Negative_regulation of PTGS2 1 778 0.59 366.76 319.85
9 INT11624 Gene_expression of OPRM1 15 445 0.78 72.36 294.36
10 INT9158 Gene_expression of Tnf 1 722 0.78 522.01 277.68
11 INT10832 Gene_expression of IL8 2 1050 0.78 698.72 270
12 INT5972 Gene_expression of IL1B 2 948 0.78 510.91 263.97
13 INT16868 Gene_expression of Il6 3 807 0.78 499.48 256.57
14 INT738 Regulation of POMC 3 459 0.62 111.19 243.74
15 INT6482 Positive_regulation of Gene_expression of TNF 7 659 0.70 569.88 210
16 INT2391 Negative_regulation of PTGS1 2 501 0.59 207.62 205.6
17 INT11313 Positive_regulation of Il6 1 526 0.70 331.27 201.59
18 INT24326 Gene_expression of Ngf 7 346 0.78 218.67 184.71
19 INT739 Negative_regulation of POMC 1 358 0.59 102.28 166.77
20 INT4768 Positive_regulation of OPRM1 1 212 0.70 31.09 164.28
21 INT5116 Gene_expression of IL2 1 670 0.78 291.13 146.69
22 INT48895 Gene_expression of Il10 4 333 0.78 221.2 138.52
23 INT695 Binding of POMC 7 304 0.48 56.66 126.85
24 INT9235 Negative_regulation of Gene_expression of TNF 1 346 0.59 252.98 118.61
25 INT50674 Gene_expression of PTGS2 2 459 0.78 253.33 118.51
26 INT12339 Localization of IL8 3 437 0.81 251.87 117.39
27 INT27096 Positive_regulation of Nfkb1 1 325 0.70 195.11 109.06
28 INT10838 Positive_regulation of IL8 1 381 0.70 295.51 101.62
29 INT4860 Positive_regulation of CALCA 1 148 0.00 73.35 97.61
30 INT21793 Positive_regulation of Ngf 2 154 0.70 94.78 85.27
31 INT7528 Regulation of OPRM1 1 100 0.62 20.63 80.57
32 INT48244 Gene_expression of Il4 4 172 0.76 132.38 73.42
33 INT58400 Negative_regulation of Tnf 1 182 0.59 129.97 71
34 INT11318 Gene_expression of Gtf3a 1 274 0.52 183.82 60.89
35 INT9196 Gene_expression of PTGS1 2 215 0.77 96.99 60.5
36 INT14740 Gene_expression of TGFB1 3 272 0.78 168.48 60.18
37 INT647 Gene_expression of SGCG 2 211 0.75 78.46 55.82
38 INT69876 Negative_regulation of Nfkb1 1 147 0.58 89.81 55.5
39 INT52800 Negative_regulation of Gene_expression of Tnf 1 142 0.59 92.27 55.47
40 INT9234 Negative_regulation of Gene_expression of IL6 1 171 0.59 101.61 53.15
41 INT27954 Positive_regulation of Gene_expression of Ngf 2 87 0.70 57.91 51.96
42 INT52264 Gene_expression of IK 1 180 0.77 90.87 51.87
43 INT5781 Gene_expression of Edn1 1 190 0.78 99.1 46
44 INT73502 Positive_regulation of IL10 2 154 0.69 124.87 43.5
45 INT1319 Gene_expression of Oprl1 2 65 0.78 9.34 42.41
46 INT13354 Transcription of TNF 1 108 0.72 85.81 42.32
47 INT64440 Gene_expression of Pnoc 3 66 0.78 13.61 41.76
48 INT9094 Gene_expression of COL7A1 5 277 0.77 143.42 38.73
49 INT1931 Positive_regulation of Gene_expression of POMC 4 116 0.70 37.26 38.67
50 INT20210 Localization of Ngf 1 69 0.79 46.22 38.57
51 INT65889 Gene_expression of RETNLB 2 73 0.34 60.98 38.3
52 INT48222 Positive_regulation of Localization of IL8 1 123 0.59 78.04 37.2
53 INT77407 Regulation of Gene_expression of OPRM1 1 51 0.62 12.58 35.75
54 INT7675 Gene_expression of ENG 1 146 0.77 45.35 34.6
55 INT11764 Positive_regulation of ENG 1 78 0.61 27.65 33.69
56 INT9694 Positive_regulation of Csf2 1 102 0.68 70.09 33.07
57 INT56290 Negative_regulation of Gene_expression of Il6 1 79 0.59 47.98 31.07
58 INT69483 Transcription of OPRM1 4 45 0.72 7.31 30.22
59 INT77652 Negative_regulation of Gene_expression of IL8 1 99 0.59 67.57 30.21
60 INT651 Positive_regulation of PTGS1 1 93 0.69 37.27 29.18
61 INT1196 Positive_regulation of Positive_regulation of POMC 2 51 0.70 15.99 28.58
62 INT6364 Gene_expression of Edn1 1 123 0.78 73.76 28.43
63 INT6174 Regulation of Gene_expression of POMC 1 49 0.61 9.75 27.69
64 INT16428 Positive_regulation of Gtf3a 3 135 0.20 106.44 26.67
65 INT48240 Binding of Ngf 1 46 0.46 23.51 24.42
66 INT7383 Localization of VIP 2 53 0.81 17.7 22.65
67 INT14731 Positive_regulation of TGFB1 1 78 0.67 52.57 22.23
68 INT14733 Positive_regulation of Gene_expression of TGFB1 1 71 0.69 49.89 22.2
69 INT14700 Regulation of IFNA1 2 111 0.45 66.16 21.52
70 INT101517 Negative_regulation of PPARA 1 168 0.57 112.24 21.41
71 INT52106 Negative_regulation of Localization of IL8 1 57 0.52 22.81 20.8
72 INT69877 Positive_regulation of Positive_regulation of Nfkb1 1 53 0.68 31.44 20.7
73 INT14701 Negative_regulation of IFNA1 2 118 0.54 84.19 20.08
74 INT69304 Negative_regulation of Il10 1 47 0.59 36.88 19.79
75 INT74286 Regulation of Il10 1 42 0.44 28.06 19.44
76 INT14737 Gene_expression of FN1 1 117 0.78 78.74 18.99
77 INT89594 Gene_expression of Ccl5 3 44 0.54 24.08 18.62
78 INT10833 Regulation of Gene_expression of IL8 1 68 0.62 38.74 18.46
79 INT36054 Transcription of IL1B 1 53 0.72 32.64 17.31
80 INT48892 Transcription of Il10 1 31 0.71 27.26 16.77
81 INT48238 Regulation of Gene_expression of Ngf 4 25 0.62 11.48 16.42
82 INT75929 Gene_expression of IL9 3 61 0.43 24.71 16.17
83 INT9783 Gene_expression of INSRR 1 81 0.50 32.99 15.52
84 INT1416 Transcription of POMC 2 40 0.72 10.71 15.38
85 INT73351 Negative_regulation of Pnoc 1 13 0.42 5.71 14.17
86 INT76863 Negative_regulation of Gene_expression of OPRM1 4 21 0.57 6.56 13.69
87 INT69878 Positive_regulation of Gene_expression of Gtf3a 1 48 0.29 36.78 13.57
88 INT91817 Positive_regulation of RETNLB 1 22 0.34 21.4 13.12
89 INT86950 Negative_regulation of Gene_expression of Il10 1 26 0.42 18.92 12.73
90 INT51014 Transcription of IL2 1 42 0.71 21.56 12.7
91 INT67213 Transcription of Pnoc 1 18 0.67 4.66 12.17
92 INT65304 Positive_regulation of Gene_expression of MC1R 6 34 0.70 11.32 12.09
93 INT50933 Transcription of Il6 1 38 0.72 24.31 11.58
94 INT62464 Gene_expression of Ogfr 2 21 0.78 20.39 10.82
95 INT701 Localization of IGHE 1 87 0.80 40.5 10.62
96 INT1321 Localization of Oprl1 1 18 0.76 1.74 9.56
97 INT81264 Positive_regulation of Localization of Ngf 1 13 0.58 9.82 9.53
98 INT13435 Positive_regulation of RTCA 1 31 0.60 7.19 8.5
99 INT68971 Localization of Pnoc 1 10 0.73 2.95 8.43
100 INT1591 Negative_regulation of Binding of POMC 1 18 0.59 1.74 7.91
101 INT86639 Gene_expression of KRT16 9 19 0.68 12.44 7.79
102 INT101721 Positive_regulation of Transcription of OPRM1 1 8 0.48 1.22 7.74
103 INT89589 Negative_regulation of Ccl5 1 9 0.40 4.62 7.39
104 INT91609 Regulation of Gene_expression of MC1R 1 11 0.62 2.75 7.34
105 INT14732 Positive_regulation of FN1 1 46 0.69 31.17 7.33
106 INT15490 Negative_regulation of Gene_expression of COL7A1 1 40 0.58 25.97 7.18
107 INT60527 Transcription of IL10 1 16 0.56 13.57 6.42
108 INT9695 Negative_regulation of Csf2 1 41 0.57 31.65 6.28
109 INT24191 Binding of VIP 1 14 0.40 2.16 6.2
110 INT67397 Transcription of Il4 2 15 0.54 11.36 6.06
111 INT85417 Positive_regulation of Gene_expression of IK 1 17 0.09 9.38 5.73
112 INT67214 Transcription of Oprl1 1 9 0.69 1.8 5.66
113 INT75833 Negative_regulation of Positive_regulation of IL8 1 15 0.53 6.69 5.59
114 INT27952 Transcription of Ngf 1 12 0.72 5.34 5.43
115 INT58972 Gene_expression of BHLHE23 2 10 0.65 2.97 5.1
116 INT85413 Negative_regulation of IL9 1 5 0.47 4.42 4.77
117 INT85415 Positive_regulation of IL9 1 10 0.28 6.93 4.71
118 INT21254 Regulation of Positive_regulation of POMC 2 12 0.61 3.64 4.67
119 INT30160 Positive_regulation of ADRA2B 1 14 0.29 1.92 4.37
120 INT81750 Regulation of Ntrk1 1 13 0.52 6.03 4.37
121 INT25503 Gene_expression of C5AR1 2 22 0.75 21.88 4.16
122 INT92653 Gene_expression of IL12B 1 21 0.75 17.28 3.89
123 INT16723 Regulation of GBE1 1 16 0.11 4.3 3.7
124 INT31528 Regulation of TYR 2 6 0.44 0.83 3.63
125 INT12083 Regulation of TGFB1 1 22 0.53 15.4 3.6
126 INT14947 Localization of SPARCL1 1 7 0.46 11.97 3.6
127 INT15489 Negative_regulation of Gene_expression of SGCG 1 10 0.42 4.78 3.18
128 INT82879 Regulation of Ccl5 1 9 0.30 6.19 3.17
129 INT86640 Positive_regulation of Gene_expression of KRT16 4 5 0.61 2.5 2.99
130 INT95105 Gene_expression of TGFBR2 2 15 0.64 16.36 2.74
131 INT19646 Binding of KLRD1 2 9 0.04 4.27 2.35
132 INT91442 Binding of PTGDR2 1 6 0.46 1.5 2.2
133 INT101516 Positive_regulation of PPARD 1 8 0.49 4.75 2.19
134 INT92648 Positive_regulation of IL12B 1 7 0.20 4.55 2.19
135 INT60943 Positive_regulation of Transcription of Ngf 1 3 0.50 2.15 1.99
136 INT117116 Positive_regulation of Positive_regulation of MC1R 1 7 0.49 1.57 1.91
137 INT28679 Gene_expression of Tnfsf13b 2 5 0.60 2.75 1.53
138 INT28681 Gene_expression of Il1rl1 1 4 0.55 3.04 1.46
139 INT91441 Binding of MINOS1 1 3 0.03 0.31 1.35
140 INT128004 Negative_regulation of Gene_expression of MINOS1 1 4 0.04 0.51 1.31
141 INT14946 Binding of SPARCL1 1 5 0.31 6.57 1.29
142 INT14727 Regulation of FN1 1 13 0.45 5.95 1.26
143 INT69875 Negative_regulation of Binding of MC1R 1 2 0.39 0.37 1.26
144 INT128001 Gene_expression of MINOS1 1 3 0.07 0.36 1.24
145 INT26659 Regulation of HESX1 1 4 0.42 1.52 1.2
146 INT2972 Negative_regulation of Olfr525 1 3 0.36 0.95 1.2
147 INT41143 Localization of VIPR1 1 4 0.78 1.57 1.16
148 INT92654 Transcription of RETNLB 1 3 0.01 3.33 1.12
149 INT28680 Positive_regulation of Tnfsf13b 2 5 0.39 6.46 1.1
150 INT41142 Binding of VIPR1 1 5 0.20 0.07 1.02
151 INT95641 Regulation of Fbn1 1 3 0.45 3.67 0.91
152 INT80024 Negative_regulation of KLRD1 1 3 0.04 0.91 0.88
153 INT92649 Negative_regulation of Gene_expression of IL12B 1 3 0.03 2.23 0.86
154 INT135299 Binding of PTCH1 2 10 0.48 12.16 0.84
155 INT107939 Regulation of TGFBR2 1 1 0.37 0.98 0.84
156 INT6602 Gene_expression of RPS6KA6 4 3 0.56 1.75 0.82
157 INT80023 Positive_regulation of Negative_regulation of KLRD1 1 1 0.04 0.17 0.81
158 INT28682 Negative_regulation of Gene_expression of Il1rl1 1 2 0.42 0.31 0.75
159 INT86641 Regulation of Gene_expression of KRT16 1 1 0.40 0.42 0.74
160 INT101923 Binding of MICA 3 6 0.48 5.44 0.71
161 INT28684 Positive_regulation of Gene_expression of Tnfsf13b 1 1 0.39 0 0.7
162 INT28685 Negative_regulation of Gene_expression of Tnfsf13b 1 1 0.33 0 0.7
163 INT44118 Binding of CD209 5 10 0.35 8.83 0.69
164 INT69880 Positive_regulation of Positive_regulation of Gtf3a 2 8 0.03 5.25 0.68
165 INT97654 Gene_expression of RBM25 1 1 0.00 0.59 0.65
166 INT75054 Binding of MC2R 1 3 0.09 0.63 0.63
167 INT25506 Protein_catabolism of RERE 1 3 0.57 0.31 0.52
168 INT119280 Gene_expression of HFM 1 1 0.34 0.08 0.52
169 INT45338 Gene_expression of RICTOR 1 4 0.52 0.89 0.48
170 INT101515 Negative_regulation of Positive_regulation of PPARD 1 2 0.35 0.68 0.47
171 INT44156 Regulation of Scl1 2 1 0.00 0.91 0.46
172 INT13434 Positive_regulation of Positive_regulation of RTCA 1 4 0.41 0.39 0.44
173 INT92650 Regulation of Gene_expression of IL9 1 2 0.25 0.76 0.41
174 INT28683 Regulation of Gene_expression of Tnfsf13b 1 1 0.35 0 0.4
175 INT58976 Positive_regulation of RPS6KA6 2 1 0.36 0.32 0.39
176 INT58974 Regulation of BHLHE23 1 2 0.19 0.42 0.38
177 INT92651 Negative_regulation of Positive_regulation of IL9 1 1 0.00 0.8 0.38
178 INT58975 Regulation of RPS6KA6 2 1 0.33 0.33 0.37
179 INT92652 Negative_regulation of Positive_regulation of IL12B 1 1 0.03 0.99 0.36
180 INT25502 Gene_expression of RERE 1 6 0.53 1.74 0.32
181 INT81752 Binding of BPIFA4P 1 8 0.37 2.87 0.29
182 INT117115 Regulation of Positive_regulation of MC1R 1 1 0.33 0.38 0.29
183 INT25505 Protein_catabolism of C5AR1 1 2 0.64 1.29 0.24
184 INT14735 Positive_regulation of COL6A2 2 3 0.42 3.13 0.22
185 INT69879 Regulation of Positive_regulation of Gtf3a 1 2 0.03 1.59 0.22
186 INT58973 Positive_regulation of Gene_expression of RPS6KA6 1 1 0.36 0.2 0.21
187 INT131619 Positive_regulation of Positive_regulation of Dgat1 1 1 0.13 0.41 0.21
188 INT131620 Positive_regulation of Dgat1 1 1 0.18 0.4 0.2
189 INT86632 Gene_expression of 5,6,7,8 1 1 0.00 0 0.19
190 INT101922 Regulation of MICA 1 2 0.39 2.64 0.15
191 INT9693 Localization of Entpd4 1 1 0.19 0.21 0.14
192 INT14736 Gene_expression of COL6A2 2 2 0.47 1.65 0.13
193 INT14728 Positive_regulation of Gene_expression of COL6A2 1 1 0.30 0.85 0.13
194 INT25504 Protein_catabolism of DES 1 1 0.96 0.31 0.11
195 INT131616 Regulation of Olfr525 1 1 0.00 0.21 0.11
196 INT14948 Localization of CORIN 1 1 0.33 0.19 0.1
197 INT14738 Negative_regulation of Regulation of TGFB1 1 2 0.41 0.81 0.09
198 INT95640 Transcription of Fbn1 1 1 0.53 0.21 0.08
199 INT14729 Positive_regulation of Positive_regulation of COL6A2 1 1 0.30 0.71 0.04
200 INT14739 Negative_regulation of Regulation of COL6A2 1 1 0.26 0.75 0.03
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox