J:J. Lab. Clin. Med.

This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT32444	Binding of Cpe and Pomc	2	1	0.22	0	4.47
2	INT42579	SOD1 Negative_regulation of POMC	1	1	0.16	0.43	1.27
3	INT42580	CAT Negative_regulation of POMC	1	1	0.20	0.42	1.26
4	INT103031	Calca Positive_regulation of Ptgs1	2	1	0.46	0.98	1.22
5	INT96089	Binding of F2 and Pf4	1	2	0.00	1.31	0.56
6	INT96098	Binding of PPBP and F2	1	2	0.00	1.31	0.56
7	INT103032	Calca Positive_regulation of Calca Positive_regulation of Nos3	1	1	0.24	0.41	0.46
8	INT103025	Calca Positive_regulation of Nos3	1	1	0.25	0.41	0.46
9	INT39870	Odc1 Negative_regulation of Tk1	1	2	0.36	0.8	0.46
10	INT103027	Ptgis Positive_regulation of Nos3	1	1	0.06	0.42	0.46
11	INT96103	Binding of PPBP and Selp	1	2	0.00	1.22	0.46
12	INT103026	Ptgis Positive_regulation of Ptgs1	1	1	0.02	0.42	0.46
13	INT103029	Calca Positive_regulation of Positive_regulation of Ptgs1	1	1	0.12	0.41	0.46
14	INT103030	Calca Positive_regulation of Positive_regulation of Nos3	1	1	0.26	0.41	0.46
15	INT96083	Binding of PPBP and SELP	1	2	0.02	1.21	0.46
16	INT96095	Binding of Selp and Pf4	1	2	0.01	1.2	0.45
17	INT96097	Binding of SELP and Pf4	1	2	0.13	1.2	0.45
18	INT103028	Calca Positive_regulation of Gene_expression of Ptgis	1	1	0.17	0.58	0.44
19	INT32445	Pomc Positive_regulation of Il1f5	1	1	0.21	0	0.34
20	INT96096	Binding of Serpinc1 and Selp	1	1	0.00	0.69	0.3
21	INT96102	Binding of TAT and Selp	1	1	0.04	0.7	0.3
22	INT96082	Binding of SELP and TAT	1	1	0.40	0.69	0.3
23	INT96100	Binding of SELP and F2	1	1	0.01	0.67	0.29
24	INT96101	Binding of SELP and Serpinc1	1	1	0.01	0.69	0.29
25	INT96094	Binding of Selp and F2	1	1	0.00	0.67	0.29
26	INT96099	Binding of TAT and F2	1	1	0.01	0.68	0.29
27	INT96093	Binding of Serpinc1 and F2	1	1	0.00	0.68	0.29
28	INT58588	IFNG Positive_regulation of ARHGAP4	1	3	0.31	1.22	0.19
29	INT83514	SERPINC1 Negative_regulation of F2	2	1	0.16	0.62	0.16
30	INT83512	F2 Negative_regulation of PLAU	1	1	0.27	0.57	0.16
31	INT83513	Negative_regulation of SERPINC1 Negative_regulation of F2	1	1	0.16	0.64	0.16
32	INT83515	F2 Positive_regulation of PLAU	1	1	0.31	0.57	0.16
33	INT83511	F2 Negative_regulation of PRH1	1	1	0.01	0.6	0.15
34	INT58586	IFNG Positive_regulation of Gene_expression of PLG	1	1	0.41	0.38	0.06

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT796	Gene_expression of Penk	9	1902	0.78	275.47	1057.59
2	INT1912	Gene_expression of Calca	1	1152	0.78	453.25	739.84
3	INT728	Positive_regulation of Penk	1	1068	0.70	186.9	636.87
4	INT797	Regulation of Penk	1	812	0.62	111.13	542.24
5	INT6580	Negative_regulation of Ptgs1	2	929	0.59	381.53	376.26
6	INT720	Positive_regulation of POMC	1	807	0.70	237.37	353.83
7	INT34869	Negative_regulation of PTGS2	2	778	0.59	366.76	319.85
8	INT9158	Gene_expression of Tnf	3	722	0.78	522.01	277.68
9	INT48955	Gene_expression of Nos2	4	753	0.78	403.87	208.08
10	INT798	Positive_regulation of Gene_expression of Penk	1	394	0.70	78.53	203.07
11	INT739	Negative_regulation of POMC	1	358	0.59	102.28	166.77
12	INT1114	Localization of Ins1	2	748	0.80	192.95	165.48
13	INT6108	Gene_expression of Npy	1	292	0.78	110.65	148.21
14	INT13353	Positive_regulation of Tnf	3	332	0.70	248.75	148.1
15	INT812	Localization of INS	1	1026	0.81	515.6	145.31
16	INT50674	Gene_expression of PTGS2	1	459	0.78	253.33	118.51
17	INT5283	Positive_regulation of Npy	1	191	0.70	66.77	109.2
18	INT1472	Positive_regulation of Ins1	1	349	0.69	146.2	86.36
19	INT148	Positive_regulation of Gnrhr	4	182	0.70	47.44	79.64
20	INT64636	Positive_regulation of Gene_expression of Nos2	2	242	0.70	147.52	79.53
21	INT2431	Positive_regulation of Mpo	3	275	0.70	211.99	78.47
22	INT1080	Negative_regulation of Ache	1	343	0.59	108.51	72.4
23	INT49995	Positive_regulation of Gene_expression of Tnf	2	187	0.70	125.07	70.54
24	INT8357	Gene_expression of KNG1	1	153	0.75	77.26	68.66
25	INT1988	Positive_regulation of Localization of Ins1	1	254	0.69	59.25	68.37
26	INT15613	Negative_regulation of Ptgs2	1	160	0.59	71.08	65.08
27	INT4509	Gene_expression of IGG	1	426	0.76	293.69	56.64
28	INT1200	Negative_regulation of Ins1	1	274	0.58	155.17	56.14
29	INT2276	Regulation of Ins1	1	234	0.61	103.78	54.05
30	INT48952	Negative_regulation of Nos2	1	204	0.59	101.73	53.15
31	INT5759	Positive_regulation of Ptgs1	2	127	0.69	53.45	53.04
32	INT5338	Regulation of Npy	1	92	0.62	25.54	51.24
33	INT2463	Localization of CCK	3	101	0.81	37.54	47.59
34	INT2406	Gene_expression of CCK	1	85	0.78	28.04	46.67
35	INT2275	Negative_regulation of Localization of Ins1	2	183	0.59	51.02	44.94
36	INT1474	Regulation of Localization of Ins1	2	132	0.61	25.96	43.07
37	INT2429	Negative_regulation of Mpo	1	128	0.59	93.76	39.57
38	INT47939	Gene_expression of Selp	3	171	0.76	87.54	39.03
39	INT55135	Positive_regulation of Gene_expression of PTGS2	1	137	0.70	80.32	38.46
40	INT326	Gene_expression of Gnrhr	4	105	0.76	35.87	34.93
41	INT2884	Positive_regulation of CCK	1	66	0.69	25.25	30.6
42	INT2671	Positive_regulation of Odc1	1	82	0.70	11.03	29
43	INT91775	Gene_expression of Slc6a4	1	102	0.78	26.45	28.23
44	INT3076	Regulation of KNG1	2	52	0.60	20.39	27.89
45	INT74726	Negative_regulation of Slc6a4	1	61	0.59	21.01	27.84
46	INT2569	Gene_expression of Ache	2	120	0.78	26.29	26.89
47	INT5650	Gene_expression of Mpo	2	117	0.77	80.27	26.42
48	INT49141	Gene_expression of Selp	2	157	0.78	85.22	24.78
49	INT2290	Protein_catabolism of POMC	5	41	0.99	4.86	23.36
50	INT11829	Negative_regulation of Odc1	3	54	0.59	7.03	23.03
51	INT66753	Negative_regulation of Positive_regulation of Tnf	1	45	0.59	35.28	22.33
52	INT21503	Binding of Ptgs1	1	45	0.48	15.6	22.29
53	INT8580	Gene_expression of ELANE	1	132	0.75	62.98	21.79
54	INT9079	Gene_expression of PPBP	1	52	0.75	31.2	21.52
55	INT3952	Negative_regulation of ALB	2	116	0.59	72.18	18.35
56	INT83198	Positive_regulation of Nos3	1	78	0.64	35.69	17.71
57	INT8056	Regulation of Positive_regulation of Penk	1	34	0.59	4.71	17.66
58	INT4853	Regulation of Hrh2	1	42	0.45	22.34	16.65
59	INT1154	Negative_regulation of CCK	2	24	0.59	9.3	15.32
60	INT22276	Gene_expression of TBXA2R	1	65	0.77	23.22	14.21
61	INT11069	Positive_regulation of Pf4	1	35	0.68	27.7	13.96
62	INT2336	Negative_regulation of Lct	2	51	0.58	33.79	13.73
63	INT3112	Regulation of Odc1	3	39	0.62	4.73	13.69
64	INT11071	Positive_regulation of PPBP	1	43	0.68	26.85	13.43
65	INT5649	Negative_regulation of Positive_regulation of Mpo	1	31	0.59	26.62	11.92
66	INT4047	Binding of F13A1	1	105	0.43	66.54	11.81
67	INT49142	Gene_expression of SELP	1	94	0.75	54.61	11.64
68	INT14204	Protein_catabolism of KNG1	1	41	0.96	20.94	11.47
69	INT19944	Negative_regulation of IFNG	2	39	0.58	22.35	10.91
70	INT14962	Gene_expression of Pf4	1	27	0.76	22.48	10.88
71	INT66303	Regulation of Slc6a4	1	10	0.45	4.82	10.55
72	INT32581	Positive_regulation of C4B	1	9	0.45	11.17	9.05
73	INT2885	Positive_regulation of Localization of CCK	2	19	0.70	9.92	8.94
74	INT15705	Negative_regulation of co	1	46	0.42	7.9	8.18
75	INT32579	Binding of C4B	1	14	0.36	14.99	7.79
76	INT32580	Gene_expression of C4B	2	24	0.75	17.95	7.75
77	INT6335	Binding of TSPO	1	39	0.44	10.88	7.66
78	INT17501	Negative_regulation of F2	1	70	0.58	32.23	7.51
79	INT63169	Positive_regulation of Gene_expression of Selp	1	35	0.69	21.95	7.16
80	INT21138	Binding of ADRA2A	1	16	0.48	5.57	6.8
81	INT63170	Positive_regulation of Selp	1	27	0.68	24.1	6.3
82	INT14258	Regulation of TSPO	1	32	0.60	10.16	6.24
83	INT4561	Gene_expression of PLG	1	32	0.75	17.59	6.21
84	INT17086	Binding of HSD11B1	1	84	0.47	122.28	6.16
85	INT8866	Positive_regulation of TAT	2	30	0.67	18.06	5.57
86	INT13295	Positive_regulation of Cdkn2a	2	18	0.68	13.02	5.47
87	INT40638	Binding of HRH1	1	14	0.44	5.81	5.09
88	INT18345	Positive_regulation of Positive_regulation of Gnrhr	2	16	0.42	4.99	4.91
89	INT12104	Positive_regulation of PLG	1	45	0.68	28.94	4.81
90	INT30444	Negative_regulation of Protein_catabolism of POMC	1	4	0.51	2.11	4.53
91	INT44578	Binding of Hbb	2	19	0.48	3.12	4.2
92	INT4530	Regulation of Ggh	1	9	0.54	2.5	3.96
93	INT66242	Gene_expression of Ptgis	4	15	0.64	6.73	3.84
94	INT103021	Transcription of Slc6a4	1	16	0.70	3.93	3.77
95	INT5320	Gene_expression of PTGFR	1	18	0.59	12.99	3.7
96	INT33739	Gene_expression of ITGA2B	2	25	0.75	8.19	3.6
97	INT13878	Negative_regulation of Ugt1a2	1	9	0.33	2.85	3.48
98	INT42581	Regulation of Gene_expression of ELANE	1	11	0.38	9.25	3.38
99	INT16588	Positive_regulation of Gene_expression of Gnrhr	2	14	0.62	4.76	3.35
100	INT31450	Binding of HIST1H1B	1	20	0.37	10.21	2.84
101	INT10141	Gene_expression of A2M	1	11	0.35	9.37	2.75
102	INT96092	Binding of ANXA5	1	24	0.36	14.51	2.6
103	INT25449	Positive_regulation of Gene_expression of PPBP	1	5	0.46	3.77	2.57
104	INT16964	Binding of IFNG	2	27	0.48	14.31	2.45
105	INT96084	Binding of Selp	1	12	0.48	8.41	2.16
106	INT64676	Gene_expression of ANXA5	1	11	0.75	13.48	2.11
107	INT42583	Protein_catabolism of ELANE	1	8	0.89	4.33	2.11
108	INT17268	Localization of PLG	1	9	0.78	11.71	2.06
109	INT35146	Negative_regulation of PLG	3	27	0.57	17.63	1.98
110	INT66237	Positive_regulation of Ptgis	2	5	0.33	1.49	1.96
111	INT38268	Positive_regulation of BEST1	2	16	0.17	14.54	1.93
112	INT78960	Binding of SOAT1	1	9	0.36	2.56	1.92
113	INT21487	Negative_regulation of HCC	1	18	0.49	29.81	1.88
114	INT103024	Positive_regulation of Gene_expression of Ptgis	2	5	0.48	4.02	1.83
115	INT21813	Gene_expression of Apoa2	1	10	0.61	3.68	1.81
116	INT37758	Gene_expression of GC	1	10	0.75	7.09	1.75
117	INT26451	Gene_expression of KLK1	2	14	0.75	5.79	1.66
118	INT21962	Localization of KLK1	1	15	0.78	3.54	1.61
119	INT20509	Positive_regulation of Negative_regulation of Ins1	1	7	0.48	2.8	1.46
120	INT42959	Negative_regulation of Vom2r2	1	3	0.06	0.56	1.43
121	INT14205	Regulation of KLK1	1	10	0.60	4.38	1.28
122	INT7991	Gene_expression of SPANXA1	1	8	0.67	3.41	1.2
123	INT35104	Positive_regulation of GC	1	6	0.11	4.99	1.08
124	INT42104	Regulation of Cdkn2a	1	4	0.44	5.67	1.06
125	INT98992	Binding of Vcam1	1	13	0.34	12.97	1.04
126	INT28066	Regulation of fut10	1	4	0.10	2.01	0.96
127	INT7614	Regulation of Vom2r2	1	2	0.04	0.87	0.89
128	INT40639	Binding of CHRM1	1	2	0.26	0.43	0.87
129	INT3086	Binding of Pf4	1	14	0.47	7.1	0.86
130	INT18146	Gene_expression of lt	2	6	0.66	2.88	0.84
131	INT28885	Regulation of Tk1	3	6	0.47	2.53	0.82
132	INT103023	Positive_regulation of Positive_regulation of Ptgis	1	1	0.18	0.7	0.8
133	INT23629	Negative_regulation of fut10	3	6	0.40	1.81	0.77
134	INT30429	Positive_regulation of Binding of OR2H2	1	1	0.21	0.58	0.66
135	INT30430	Binding of OR2H2	1	1	0.15	0.57	0.65
136	INT28886	Negative_regulation of Tk1	3	5	0.45	1.66	0.64
137	INT50016	Positive_regulation of ARHGAP4	1	3	0.49	1.8	0.58
138	INT23630	Gene_expression of fut10	1	5	0.62	0.9	0.54
139	INT28065	Negative_regulation of Gene_expression of fut10	1	2	0.04	0.53	0.53
140	INT30428	Positive_regulation of Binding of ADRA2A	1	1	0.34	0.59	0.53
141	INT10983	Binding of Apoa2	2	7	0.45	4.21	0.52
142	INT58591	Negative_regulation of Positive_regulation of PLG	1	4	0.42	2.46	0.51
143	INT15715	Positive_regulation of LTB	1	2	0.67	1.4	0.45
144	INT42105	Regulation of Positive_regulation of Cdkn2a	1	1	0.44	0.33	0.42
145	INT40640	Binding of BAP1	1	1	0.05	0.09	0.39
146	INT50014	Negative_regulation of ARHGAP4	3	2	0.27	1.59	0.32
147	INT84920	Regulation of Gene_expression of lt	1	1	0.03	0.5	0.22
148	INT103022	Positive_regulation of Transcription of Slc6a4	1	2	0.44	0.52	0.21
149	INT58589	Regulation of F12	1	3	0.39	1.9	0.16
150	INT58590	Protein_catabolism of IFNG	1	2	0.84	0.75	0.1
151	INT58594	Regulation of ARHGAP4	1	1	0.21	0.65	0.1
152	INT58593	Regulation of Negative_regulation of ARHGAP4	1	1	0.21	0.53	0.07
153	INT58592	Negative_regulation of Protein_catabolism of IFNG	1	1	0.40	0.51	0.07
154	INT35144	Negative_regulation of Gene_expression of PLG	1	3	0.29	0.98	0.06
155	INT34916	Positive_regulation of Localization of Hdlcl1	1	1	0.02	1.64	0
156	INT101924	Positive_regulation of Procr	1	1	0.07	0.69	0
157	INT34915	Localization of Hdlcl1	1	1	0.03	1.61	0