J:J. Mol. Neurosci.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT146520 Tmem132a Regulation of Gene_expression of Fos 1 2 0.69 0.5 2.18
2 INT153533 NMS Regulation of Gene_expression of Ephb1 1 3 0.48 3.96 1.93
3 INT146512 Tmem132a Negative_regulation of Gene_expression of Fos 1 1 0.23 0 1.76
4 INT146518 Tmem132a Positive_regulation of Gene_expression of Fos 1 1 0.68 0.06 1.04
5 INT153532 NMS Regulation of Gene_expression of Fos 1 1 0.23 1.33 0.67
6 INT153534 Binding of Ephb1 and NMS 1 1 0.29 1.13 0.5
7 INT69073 Adcyap1 Regulation of Localization of Gnrh1 2 1 0.66 0 0.22
8 INT85916 CAMP Positive_regulation of CREM 1 2 0.22 0 0.18
9 INT110952 Adcyap1 Regulation of Localization of LH 1 1 0.22 0 0.07
10 INT78615 Pdpk1 Regulation of Gene_expression of Penk 1 2 0.03 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 17 3083 0.78 894.43 1639.02
2 INT2542 Localization of Calca 1 2008 0.81 518.3 1408.65
3 INT796 Gene_expression of Penk 11 1902 0.78 275.47 1057.59
4 INT1912 Gene_expression of Calca 1 1152 0.78 453.25 739.84
5 INT5202 Positive_regulation of Gene_expression of Fos 5 1163 0.70 319.28 684
6 INT2543 Positive_regulation of Calca 4 787 0.70 331.13 592.08
7 INT1045 Localization of LH 2 1211 0.81 87.04 456.25
8 INT4758 Positive_regulation of Localization of Calca 1 557 0.70 138.55 411.04
9 INT6056 Negative_regulation of Gene_expression of Fos 4 601 0.59 193.05 386.84
10 INT2540 Negative_regulation of Calca 1 538 0.59 172.11 384.38
11 INT439 Localization of Gnrh1 1 976 0.81 100.96 363.25
12 INT2649 Regulation of Calca 2 433 0.62 146.05 330.95
13 INT5680 Gene_expression of Ngf 2 530 0.78 264.29 310.56
14 INT63932 Positive_regulation of Ephb1 2 537 0.70 259.67 296.14
15 INT886 Gene_expression of Pomc 2 676 0.78 129.87 295.98
16 INT5591 Regulation of Gene_expression of Fos 2 425 0.62 129.06 265.78
17 INT1893 Localization of Gh 5 1041 0.79 340.23 256.58
18 INT1005 Localization of Sst 1 385 0.81 26.31 244.56
19 INT11377 Positive_regulation of Ngf 1 331 0.70 206.5 238
20 INT5597 Gene_expression of Pdyn 18 433 0.78 62.97 235.47
21 INT1308 Localization of Pomc 1 457 0.81 66.83 217.5
22 INT16259 Positive_regulation of Bdnf 4 336 0.70 183.48 209.82
23 INT6488 Gene_expression of Tnf 3 484 0.78 339.61 191.58
24 INT94952 Positive_regulation of Mapk14 1 305 0.70 197.83 186.61
25 INT4803 Transcription of Penk 4 435 0.72 59.09 182.4
26 INT49441 Negative_regulation of Cpox 2 494 0.59 303.22 177.46
27 INT943 Negative_regulation of Cck 2 205 0.59 38.42 174.78
28 INT5513 Negative_regulation of Pomc 5 295 0.59 60.9 158.63
29 INT1044 Negative_regulation of Localization of LH 1 358 0.59 25.95 151.31
30 INT2780 Regulation of Gene_expression of Penk 4 265 0.62 32.45 143.88
31 INT2541 Binding of Calca 1 200 0.48 67.14 134.62
32 INT49439 Gene_expression of Cpox 1 508 0.73 326.97 130.17
33 INT5595 Positive_regulation of Pdyn 8 223 0.70 48.37 130.14
34 INT5842 Gene_expression of Gfap 1 372 0.78 153.71 127.71
35 INT1793 Localization of CGA 2 379 0.81 67.38 114.69
36 INT48923 Gene_expression of Ephb1 7 211 0.77 106.23 109.9
37 INT397 Localization of SST 1 232 0.81 58.05 101.19
38 INT97701 Phosphorylation of Mapk14 1 191 0.82 115.33 100.46
39 INT74058 Gene_expression of Nos1 1 260 0.78 80.04 95.71
40 INT5865 Positive_regulation of Localization of Gh 2 282 0.69 84.86 93.5
41 INT5594 Regulation of Pdyn 4 137 0.62 27.04 86.63
42 INT4631 Positive_regulation of Sst 1 127 0.70 17.37 83.29
43 INT16254 Positive_regulation of Gene_expression of Ngf 1 144 0.70 80.61 82.08
44 INT1497 Negative_regulation of Gh 1 415 0.59 192.95 74.71
45 INT5593 Positive_regulation of Gene_expression of Pdyn 6 114 0.70 29.1 74.46
46 INT39565 Gene_expression of Ptger2 1 424 0.75 229.28 72.68
47 INT2055 Regulation of Gnrh1 2 185 0.62 23.65 71.26
48 INT6489 Positive_regulation of Gene_expression of Tnf 1 140 0.70 92.31 67.85
49 INT6824 Regulation of Gene_expression of Pdyn 9 114 0.62 9.48 66.73
50 INT6486 Positive_regulation of Tnf 5 168 0.70 123.47 66.05
51 INT6894 Gene_expression of CNR1 1 168 0.78 74.07 62.84
52 INT1794 Regulation of Localization of CGA 1 136 0.57 13.39 59.07
53 INT5598 Negative_regulation of Pdyn 5 95 0.59 14.4 55.43
54 INT6826 Transcription of Pdyn 4 130 0.71 22.19 54.88
55 INT1486 Negative_regulation of Cpe 1 85 0.59 28.78 54.08
56 INT49028 Positive_regulation of Nos1 1 102 0.70 34.73 51.05
57 INT1232 Positive_regulation of Pdpk1 1 78 0.42 24.33 50.17
58 INT51163 Gene_expression of Gal 1 119 0.78 67.48 49.23
59 INT1894 Negative_regulation of Localization of Gh 2 168 0.58 64.12 43.56
60 INT16194 Binding of CNR1 7 82 0.48 20.75 39.59
61 INT11292 Gene_expression of Mme 2 77 0.78 20.98 35.85
62 INT17381 Gene_expression of Tbxa2r 1 146 0.78 65.01 34.15
63 INT48924 Positive_regulation of Mapk3 1 107 0.67 50.53 34.05
64 INT95734 Phosphorylation of Mapk8 1 108 0.82 49.92 33.52
65 INT7286 Regulation of Transcription of Penk 2 81 0.62 9.25 33.45
66 INT8027 Regulation of Gene_expression of Ngf 1 34 0.62 26.32 31.16
67 INT72375 Phosphorylation of Mapk3 1 87 0.80 43.66 30.27
68 INT7412 Positive_regulation of SST 1 71 0.70 24.44 29.48
69 INT17331 Positive_regulation of JUN 2 132 0.69 60.4 27.03
70 INT47685 Positive_regulation of Positive_regulation of Bdnf 1 32 0.70 20.05 27.03
71 INT74688 Regulation of Nos1 2 55 0.62 22.16 25.3
72 INT77793 Positive_regulation of Gdnf 2 54 0.70 23.76 25.08
73 INT5596 Negative_regulation of Gene_expression of Pdyn 1 41 0.59 5.34 24.36
74 INT44954 Gene_expression of APP 2 191 0.78 105.86 23.9
75 INT7113 Negative_regulation of Localization of CGA 1 71 0.51 17.7 23.42
76 INT9526 Negative_regulation of Localization of Pomc 1 41 0.58 6.93 23.3
77 INT5511 Negative_regulation of Gene_expression of Pomc 1 47 0.59 12.08 23.02
78 INT29704 Regulation of Casp3 2 51 0.56 22.13 22.79
79 INT106720 Positive_regulation of Adcy1 2 30 0.50 22.05 22.68
80 INT4612 Positive_regulation of Localization of CGA 1 64 0.64 8.51 22.39
81 INT45437 Localization of Acot1 3 84 0.79 17.37 22.18
82 INT69993 Positive_regulation of Gene_expression of Cpox 1 93 0.55 69.4 22.05
83 INT693 Negative_regulation of Localization of SST 1 46 0.59 8.57 21.75
84 INT74059 Positive_regulation of Gene_expression of Nos1 1 55 0.70 11.5 21.39
85 INT5586 Binding of Fos 2 47 0.48 12.7 21.33
86 INT53575 Regulation of Gene_expression of Tnf 1 46 0.62 34.35 20.63
87 INT48144 Gene_expression of Fgf2 1 117 0.78 43 20.48
88 INT10442 Negative_regulation of CNR1 6 47 0.59 20.88 20.2
89 INT125411 Negative_regulation of Phosphorylation of Mapk14 1 31 0.57 18.55 19.98
90 INT9490 Regulation of Mme 1 44 0.56 6.69 19.21
91 INT26972 Negative_regulation of Tenc1 1 57 0.57 56.71 16.87
92 INT54077 Gene_expression of Adcyap1 5 62 0.78 23.17 16.75
93 INT11918 Localization of CGB 1 35 0.51 8.21 15.01
94 INT58896 Localization of Adcyap1 1 35 0.81 4.57 14.77
95 INT14453 Localization of Mme 2 44 0.80 2.46 14.75
96 INT11980 Positive_regulation of Tac1 1 27 0.69 6.17 14.5
97 INT61548 Positive_regulation of Fgf2 1 72 0.70 32.18 14.49
98 INT95738 Positive_regulation of Phosphorylation of Mapk8 1 40 0.70 23.46 13.88
99 INT130424 Negative_regulation of Adcy1 1 19 0.58 16.31 13.6
100 INT18372 Positive_regulation of Transcription of Pdyn 1 30 0.69 2.48 12.83
101 INT78797 Regulation of Tmem132a 1 8 0.45 3.61 12.73
102 INT28420 Gene_expression of Ptgds 1 59 0.78 31.72 12.67
103 INT15136 Regulation of Positive_regulation of Calca 2 12 0.62 3.02 12.16
104 INT7350 Negative_regulation of Anpep 2 30 0.59 2.89 11.28
105 INT6870 Positive_regulation of Oprk1 1 14 0.70 4 10.91
106 INT10119 Positive_regulation of Positive_regulation of Pdyn 2 14 0.69 2.67 10.81
107 INT27687 Regulation of Cp 1 20 0.53 9.75 10.8
108 INT3982 Gene_expression of Acot1 1 53 0.56 7.61 10.46
109 INT41569 Regulation of APP 1 32 0.62 17.15 9.4
110 INT8524 Regulation of Transcription of Pdyn 1 20 0.60 5.47 9.03
111 INT73010 Gene_expression of Tmem132a 3 8 0.77 4.38 8.86
112 INT3622 Regulation of CTSB 1 34 0.58 16.08 8.76
113 INT18519 Positive_regulation of Negative_regulation of Pdyn 3 6 0.47 0.14 8.72
114 INT21566 Regulation of Oprk1 2 10 0.62 3.4 8.63
115 INT13346 Regulation of Localization of CGB 1 18 0.30 1.29 8.32
116 INT53798 Gene_expression of Oprk1 1 14 0.73 1.82 8.24
117 INT12010 Gene_expression of Cp 1 38 0.65 20.55 7.84
118 INT98178 Localization of Casp3 1 32 0.65 21.01 7.77
119 INT72372 Positive_regulation of Phosphorylation of Mapk3 1 30 0.67 13.6 7.69
120 INT11441 Negative_regulation of Anpep 1 18 0.59 3.73 7.51
121 INT75497 Regulation of JUN 1 28 0.61 11.04 7.09
122 INT49506 Regulation of Ptger2 1 29 0.44 17.38 6.75
123 INT7376 Positive_regulation of CAMP 1 17 0.67 6.39 6.6
124 INT85923 Positive_regulation of CREM 2 25 0.67 7.03 6.53
125 INT88839 Gene_expression of St3gal3 1 12 0.35 2.47 6.44
126 INT10445 Transcription of CNR1 2 16 0.68 6.75 6.4
127 INT24527 Negative_regulation of Gal 1 12 0.59 7.16 6.29
128 INT55077 Positive_regulation of Positive_regulation of Pdpk1 1 6 0.26 1.77 5.78
129 INT92280 Transcription of OPRL1 1 10 0.70 1.36 5.68
130 INT159866 Gene_expression of Slc23a2 4 1 0.77 1.04 5.18
131 INT126847 Binding of Ephb1 2 15 0.46 6.47 5.17
132 INT34132 Binding of Oprk1 1 6 0.48 2.15 4.78
133 INT85360 Positive_regulation of Pklr 2 9 0.46 0.74 4.76
134 INT75197 Gene_expression of Umod 1 3 0.75 2.48 4.75
135 INT89271 Gene_expression of Serbp1 1 4 0.52 1.41 4.53
136 INT103875 Binding of Tmem132a 1 3 0.36 0 4.45
137 INT9456 Gene_expression of Anpep 2 9 0.78 1.69 4.26
138 INT159872 Negative_regulation of Gene_expression of Slc23a2 3 1 0.58 0.74 3.99
139 INT4236 Negative_regulation of GLYAT 1 9 0.57 4.37 3.74
140 INT112340 Gene_expression of Cyp11a1 1 11 0.77 5.19 3.7
141 INT87408 Negative_regulation of ADCY2 4 3 0.01 0.1 3.68
142 INT146516 Gene_expression of Zdhhc23 2 2 0.49 3.57 3.63
143 INT80923 Negative_regulation of Binding of CNR1 6 7 0.19 0.78 3.61
144 INT14068 Positive_regulation of Umod 1 4 0.49 2.3 3.53
145 INT58897 Regulation of Localization of Adcyap1 1 4 0.45 1.82 3.48
146 INT30238 Positive_regulation of Anpep 2 14 0.66 2.77 3.38
147 INT71473 Positive_regulation of Adcy8 1 4 0.46 1.19 3.27
148 INT128138 Positive_regulation of Positive_regulation of Adcy1 1 5 0.45 2.67 3.25
149 INT27740 Positive_regulation of COX8A 1 16 0.67 9.66 3.23
150 INT5508 Negative_regulation of Negative_regulation of Pomc 2 10 0.53 1.57 3.22
151 INT65033 Negative_regulation of Fgf2 1 21 0.59 12.36 2.94
152 INT11291 Positive_regulation of Gene_expression of Mme 1 6 0.61 5.93 2.81
153 INT85142 Gene_expression of Gtf2i 1 5 0.26 2.3 2.76
154 INT159868 Negative_regulation of Slc23a2 2 1 0.58 0.49 2.61
155 INT133571 Gene_expression of Slc16a11 1 3 0.67 0.88 2.58
156 INT64688 Negative_regulation of Gene_expression of Fgf2 1 5 0.59 5.07 2.56
157 INT159867 Gene_expression of Slc23a1 2 1 0.74 0.58 2.54
158 INT135136 Gene_expression of PEE1 3 6 0.19 3.9 2.53
159 INT58701 Regulation of Slc16a11 1 3 0.15 0.54 2.51
160 INT25166 Regulation of Tbxa2r 1 12 0.43 5.94 2.47
161 INT50367 Negative_regulation of COX8A 1 10 0.57 5.13 2.38
162 INT123682 Localization of JUN 1 8 0.50 4.15 2.38
163 INT102056 Protein_catabolism of Tenc1 1 14 0.84 6.29 2.14
164 INT74131 Positive_regulation of Tspo 1 7 0.50 0.92 2.11
165 INT51980 Protein_catabolism of Mme 1 6 0.89 2.49 2.06
166 INT35107 Positive_regulation of PEE1 2 4 0.26 2.3 2.02
167 INT107334 Negative_regulation of Pklr 1 5 0.04 0.81 1.99
168 INT89270 Negative_regulation of Gene_expression of Serbp1 1 2 0.33 0.94 1.95
169 INT135134 Positive_regulation of Gene_expression of Umod 1 2 0.49 1.13 1.91
170 INT131477 Positive_regulation of Nfe2l2 1 2 0.05 1.33 1.91
171 INT112339 Localization of Cyp11a1 2 2 0.71 0.94 1.68
172 INT153530 Positive_regulation of NMS 2 4 0.39 4.17 1.63
173 INT102064 Binding of Sstr5 1 3 0.20 0.86 1.55
174 INT121946 Positive_regulation of Pld3 2 1 0.08 0.15 1.55
175 INT28425 Regulation of Ptgds 1 4 0.28 2.07 1.53
176 INT55948 Phosphorylation of CAMP 1 4 0.80 0.52 1.49
177 INT125796 Regulation of Gene_expression of APP 1 8 0.59 5.95 1.41
178 INT143024 Positive_regulation of Nrg1 1 2 0.70 0.53 1.39
179 INT38815 Positive_regulation of Pbr 2 3 0.41 1.28 1.33
180 INT71474 Negative_regulation of Positive_regulation of Adcy8 1 2 0.05 0.26 1.32
181 INT126001 Positive_regulation of Localization of Olfr749 2 1 0.61 0.26 1.25
182 INT126000 Localization of Olfr749 2 1 0.70 0.26 1.24
183 INT159871 Regulation of Gene_expression of Slc23a2 1 1 0.45 0.35 1.21
184 INT159870 Regulation of Gene_expression of Slc23a1 1 1 0.58 0.35 1.2
185 INT159869 Regulation of Gene_expression of Slc16a11 1 1 0.02 0.37 1.18
186 INT41142 Binding of VIPR1 1 5 0.20 0.07 1.02
187 INT143025 Positive_regulation of Erbb4 1 2 0.45 0.45 0.98
188 INT135135 Positive_regulation of Gene_expression of PEE1 1 1 0.01 1.02 0.96
189 INT10578 Transcription of Cyp11a1 1 3 0.53 0.84 0.93
190 INT39838 Regulation of Gene_expression of Cp 1 6 0.17 0.64 0.91
191 INT153131 Negative_regulation of Vipr1 1 2 0.16 0.59 0.87
192 INT108264 Positive_regulation of RARB 1 2 0.67 0.06 0.83
193 INT102055 Protein_catabolism of Adamts10 1 1 0.29 0.55 0.78
194 INT121948 Negative_regulation of Positive_regulation of Pld3 1 1 0.06 0.07 0.77
195 INT121947 Negative_regulation of Positive_regulation of Gdnf 1 1 0.20 0.07 0.76
196 INT112561 Binding of PSMG1 1 21 0.34 5.89 0.67
197 INT130425 Negative_regulation of Negative_regulation of Adcy1 1 2 0.43 0.57 0.65
198 INT102063 Localization of Sstr5 2 1 0.14 0.6 0.63
199 INT121950 Regulation of Gene_expression of Oprk1 1 1 0.45 0.18 0.6
200 INT127930 Gene_expression of ADCY2 1 6 0.11 0.1 0.59
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