J:J. Neural Transm.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT25036 TRH Regulation of Prl 4 1 0.27 1.75 1.09
2 INT221 Chd7 Negative_regulation of Th 1 1 0.02 0 1.04
3 INT35252 Gene_expression of Ghrh Positive_regulation of Localization of Gh1 1 2 0.49 0 0.93
4 INT36511 Binding of Htr2a and Eef1a1 1 1 0.22 0 0.62
5 INT36512 Binding of Htr2a and Man2a2 1 1 0.19 0 0.62
6 INT45258 SLAMF6 Positive_regulation of Drd2 1 1 0.00 0 0.55
7 INT64639 Slc1a1 Positive_regulation of Ddc 1 1 0.30 0.3 0.38

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT796 Gene_expression of Penk 2 1902 0.78 275.47 1057.59
2 INT158 Localization of Prl 7 2431 0.81 378.96 952.2
3 INT3439 Localization of Abat 1 1017 0.78 112.39 727.06
4 INT292 Localization of Penk 3 876 0.81 88.44 669.14
5 INT728 Positive_regulation of Penk 1 1068 0.70 186.9 636.87
6 INT5228 Positive_regulation of Fos 2 934 0.70 209.8 503.87
7 INT155 Positive_regulation of Prl 7 1233 0.70 317.93 457.82
8 INT443 Localization of POMC 4 1020 0.81 284.52 443.17
9 INT50058 Negative_regulation of Cpox 1 907 0.58 426.28 428.29
10 INT157 Positive_regulation of Localization of Prl 5 790 0.70 104.54 374.78
11 INT876 Localization of Gh1 5 843 0.80 67.75 340.82
12 INT162 Regulation of Prl 8 794 0.62 165.01 322.24
13 INT4941 Positive_regulation of Oprd1 1 345 0.70 74.26 304.41
14 INT6406 Binding of Oprm1 1 280 0.48 40.54 226.26
15 INT767 Localization of Gnrhr 1 565 0.80 106.68 214.57
16 INT798 Positive_regulation of Gene_expression of Penk 2 394 0.70 78.53 203.07
17 INT156 Negative_regulation of Prl 2 542 0.59 131.97 192.24
18 INT2085 Positive_regulation of LH 2 441 0.70 60.15 191.02
19 INT6354 Localization of Gabrg1 1 321 0.74 41.41 186.74
20 INT739 Negative_regulation of POMC 1 358 0.59 102.28 166.77
21 INT3448 Positive_regulation of Gh 2 521 0.69 180.03 161.18
22 INT880 Positive_regulation of Localization of Gh1 3 304 0.70 14.79 150.23
23 INT2451 Positive_regulation of Avp 3 355 0.70 102.66 147.69
24 INT2780 Regulation of Gene_expression of Penk 1 265 0.62 32.45 143.88
25 INT14843 Gene_expression of Gabrg1 1 301 0.77 62.63 139.16
26 INT4658 Binding of OPRM1 2 188 0.48 25.96 136.24
27 INT1047 Negative_regulation of LH 1 314 0.59 53.71 135.89
28 INT416 Regulation of LH 3 253 0.62 31.48 125.55
29 INT218 Positive_regulation of Th 3 245 0.70 40.5 120.1
30 INT2555 Positive_regulation of Localization of Penk 1 116 0.70 24.35 119.73
31 INT4207 Regulation of Avp 1 267 0.62 63.72 115.33
32 INT915 Positive_regulation of PRL 3 342 0.70 141.96 104.31
33 INT10272 Gene_expression of Il1b 1 194 0.78 121.02 103.03
34 INT874 Positive_regulation of Gh1 1 244 0.70 27.17 97.98
35 INT1281 Negative_regulation of Maoa 1 203 0.59 22.47 91.66
36 INT214 Localization of AVP 1 370 0.81 208.51 91.09
37 INT6585 Positive_regulation of Insrr 1 110 0.52 40.67 89.9
38 INT6214 Negative_regulation of Adarb1 1 123 0.50 26.39 89.57
39 INT875 Regulation of Localization of Gh1 1 166 0.62 12.87 84.97
40 INT1309 Positive_regulation of Localization of Gnrhr 1 152 0.69 24.25 81.56
41 INT2431 Positive_regulation of Mpo 2 275 0.70 211.99 78.47
42 INT881 Negative_regulation of Localization of Gh1 1 164 0.58 15.1 75.28
43 INT1497 Negative_regulation of Gh 1 415 0.59 192.95 74.71
44 INT6490 Negative_regulation of ADCY1 1 145 0.58 26.25 70.96
45 INT5993 Positive_regulation of Nts 1 122 0.70 26.82 70.45
46 INT4637 Binding of Adarb1 1 132 0.41 14.48 67.76
47 INT47690 Regulation of Bdnf 1 118 0.62 53.02 64.5
48 INT217 Negative_regulation of Th 1 134 0.59 26.83 62.63
49 INT217 Negative_regulation of Th 1 134 0.59 26.83 62.63
50 INT6436 Positive_regulation of Positive_regulation of Fos 1 101 0.70 18.71 57.96
51 INT5453 Regulation of Localization of POMC 1 114 0.62 20.56 56.34
52 INT1782 Regulation of Gh1 1 125 0.62 22 55.74
53 INT1579 Gene_expression of PRL 1 279 0.78 119.2 55.41
54 INT6073 Negative_regulation of Localization of Penk 2 63 0.59 8.67 53.95
55 INT1487 Regulation of Cpe 1 68 0.62 10.24 52.91
56 INT1456 Regulation of Oprl1 1 61 0.62 19.5 52.87
57 INT929 Positive_regulation of Oprl1 1 64 0.70 14.67 52.84
58 INT1781 Negative_regulation of Gh1 1 127 0.59 16.94 51.77
59 INT7059 Regulation of Adra2a 1 89 0.62 18.24 48.43
60 INT7059 Regulation of Adra2a 1 89 0.62 18.24 48.43
61 INT1197 Negative_regulation of Localization of POMC 1 109 0.59 28.29 48.02
62 INT16850 Negative_regulation of Localization of Gabrg1 1 73 0.51 8.28 47.89
63 INT5337 Negative_regulation of Npy 2 87 0.59 19.6 46.75
64 INT683 Positive_regulation of AVP 1 173 0.70 74.55 46.41
65 INT9039 Negative_regulation of Htr1a 1 69 0.57 9.56 41.84
66 INT115 Negative_regulation of Maoa 2 65 0.59 16.27 38.66
67 INT4925 Binding of Tacr1 1 57 0.48 17.39 38.38
68 INT5039 Positive_regulation of Gal 1 67 0.68 27.97 37.36
69 INT13501 Binding of Drd2 2 65 0.48 23.76 35.6
70 INT1361 Negative_regulation of Gnrhr 1 118 0.58 57.77 35.54
71 INT7608 Positive_regulation of Adra2a 2 66 0.70 17.81 35.15
72 INT1705 Gene_expression of pCA 1 126 0.65 88.65 34.81
73 INT692 Negative_regulation of SST 1 72 0.59 28.68 34.52
74 INT691 Binding of SST 1 67 0.48 24.66 32.67
75 INT13897 Localization of Sst 3 65 0.81 14.91 32.24
76 INT5100 Positive_regulation of Ghrh 1 100 0.64 24.2 30.21
77 INT19396 Regulation of Rac1 1 66 0.53 37.41 30.01
78 INT12502 Regulation of Adarb1 2 50 0.53 7.58 30.01
79 INT67 Negative_regulation of Ddc 4 66 0.59 15.34 28.96
80 INT22499 Regulation of Calca 1 42 0.62 17.32 28.02
81 INT14575 Positive_regulation of Ppt1 1 60 0.70 9.97 27.4
82 INT97 Negative_regulation of Adrb1 1 102 0.59 32.44 26.9
83 INT1638 Negative_regulation of PLOD1 1 92 0.59 21.69 26.61
84 INT11773 Gene_expression of Tac1 1 56 0.77 10 25.72
85 INT5948 Regulation of Il1b 1 44 0.60 22.8 25.4
86 INT8122 Regulation of Htr1a 2 39 0.60 8.96 24.89
87 INT12424 Binding of Npy 1 48 0.48 8.23 24.26
88 INT12424 Binding of Npy 1 48 0.48 8.23 24.26
89 INT4756 Positive_regulation of Nrtim1 1 37 0.33 14.6 24.12
90 INT682 Negative_regulation of AVP 1 97 0.59 50.67 23.91
91 INT956 Negative_regulation of PRL 1 94 0.59 42.72 23.01
92 INT11077 Positive_regulation of Htr3a 1 63 0.67 15.61 22.7
93 INT7715 Regulation of Drd2 1 35 0.62 10.79 22.3
94 INT16851 Regulation of Localization of Gabrg1 1 34 0.39 4.34 22.29
95 INT16764 Transcription of Qrfp 1 39 0.69 6.29 21.61
96 INT49623 Negative_regulation of Gria1 1 39 0.59 12.4 21.59
97 INT5040 Regulation of Gal 1 42 0.60 12.72 21.18
98 INT4894 Transcription of Ppt1 2 34 0.67 5.93 21.06
99 INT11979 Transcription of Tac4 1 42 0.52 4.48 20.95
100 INT12951 Negative_regulation of Cat 1 126 0.57 64.39 20.61
101 INT519 Negative_regulation of Comt 1 52 0.59 17.65 20.39
102 INT3030 Gene_expression of Adra2a 1 37 0.68 5.58 19.76
103 INT9246 Positive_regulation of Cat 2 113 0.70 52.73 18.04
104 INT219 Negative_regulation of Th 2 55 0.59 20.88 17.09
105 INT213 Negative_regulation of Localization of AVP 1 46 0.59 19.78 16.79
106 INT9069 Regulation of Htr3a 2 29 0.60 6.18 16.55
107 INT62861 Regulation of Gria2 1 45 0.60 13.35 16.07
108 INT12617 Regulation of ADCY1 1 41 0.61 7.38 15.94
109 INT1416 Transcription of POMC 1 40 0.72 10.71 15.38
110 INT8794 Negative_regulation of Ppt1 2 35 0.57 6.44 14.52
111 INT11980 Positive_regulation of Tac1 3 27 0.69 6.17 14.5
112 INT2758 Binding of Dbp 1 36 0.44 8.3 14.47
113 INT15042 Gene_expression of Adora2a 6 37 0.77 3.77 14.24
114 INT28314 Negative_regulation of Gene_expression of Gabrg1 1 29 0.44 12.56 13.8
115 INT18658 Regulation of Adra1a 1 34 0.62 5.69 13.78
116 INT21646 Positive_regulation of Npy 1 40 0.70 31.31 13.57
117 INT2005 Positive_regulation of Gene_expression of PRL 1 55 0.70 21.4 13.44
118 INT16530 Gene_expression of Ghrh 2 45 0.77 6.22 13.44
119 INT1148 Positive_regulation of ecs 1 38 0.48 25.27 13.1
120 INT6749 Binding of Dio1 1 25 0.38 4.41 13.07
121 INT11793 Negative_regulation of CA2 1 78 0.57 19.63 12.35
122 INT7682 Binding of Drd1a 2 22 0.48 1.8 11.83
123 INT2956 Binding of H2-Ab1 2 19 0.37 3.1 11.18
124 INT10009 Positive_regulation of TRH 1 31 0.67 8.94 11.03
125 INT28843 Positive_regulation of Scn2a1 1 31 0.68 5.35 10.7
126 INT348 Regulation of Adra1a 1 25 0.45 3.33 10.27
127 INT348 Regulation of Adra1a 1 25 0.45 3.33 10.27
128 INT75955 Gene_expression of Drd3 1 19 0.77 4.39 10.07
129 INT12367 Binding of PRLR 1 17 0.03 2.05 9.69
130 INT2059 Positive_regulation of Negative_regulation of Prl 1 24 0.70 5.7 9.37
131 INT13893 Negative_regulation of Cubn 2 9 0.36 1.78 9.24
132 INT220 Negative_regulation of Ddc 3 16 0.59 2.94 8.66
133 INT220 Negative_regulation of Ddc 1 16 0.59 2.94 8.66
134 INT24651 Positive_regulation of Transcription of Ppt1 1 12 0.47 2.88 8.42
135 INT4563 Positive_regulation of Regulation of Prl 1 20 0.70 4.2 8.1
136 INT1448 Binding of Adra1a 2 23 0.48 1.41 8.01
137 INT22491 Binding of Atrn 2 23 0.30 4.51 7.79
138 INT1150 Gene_expression of ecs 1 42 0.59 29.38 7.73
139 INT298 Negative_regulation of ADRB3 1 23 0.59 6.82 7.56
140 INT74099 Negative_regulation of Dynll1 1 8 0.56 3.43 7.25
141 INT28315 Regulation of Gene_expression of Gabrg1 1 20 0.60 4.78 7
142 INT11975 Transcription of Tac1 1 24 0.71 4.06 6.72
143 INT15674 Positive_regulation of Gene_expression of Tac1 1 17 0.68 4.97 6.56
144 INT7138 Regulation of Regulation of Avp 1 10 0.36 1.99 6.37
145 INT16765 Regulation of Transcription of Qrfp 1 12 0.17 0.88 6.12
146 INT42799 Positive_regulation of Drd3 1 11 0.69 1.1 5.92
147 INT38366 Regulation of Cat 1 45 0.62 23.45 5.34
148 INT68591 Regulation of TYRP1 1 14 0.44 3.93 5.05
149 INT13650 Positive_regulation of Gene_expression of Adra2a 1 6 0.50 0.69 4.94
150 INT83492 Positive_regulation of Htr5b 1 4 0.47 1.84 4.58
151 INT51072 Positive_regulation of Positive_regulation of Htr3a 1 10 0.49 1.84 4.53
152 INT23440 Negative_regulation of Sult1b1 1 12 0.45 1.77 4.33
153 INT32569 Localization of GGH 3 18 0.80 2.46 4.3
154 INT30610 Localization of PCa 1 35 0.65 13.91 4.25
155 INT76714 Binding of Drd3 1 9 0.37 2.33 4.09
156 INT1149 Binding of ecs 1 19 0.37 13.67 3.9
157 INT68695 Gene_expression of HTT 1 63 0.77 44.54 3.69
158 INT89329 Regulation of Gene_expression of Drd3 1 4 0.61 0.72 3.56
159 INT64310 Negative_regulation of GRIN2A 1 7 0.42 2.16 3.49
160 INT4562 Regulation of Slc6a2 1 8 0.53 1.45 3.43
161 INT58475 Localization of Rac1 1 12 0.75 5.94 3.2
162 INT83493 Negative_regulation of Htr5b 1 3 0.34 1.22 3.12
163 INT137262 Positive_regulation of Slc18a2 2 5 0.68 1.45 3.1
164 INT5648 Negative_regulation of Mptp1 1 7 0.37 6.64 3.08
165 INT27100 Binding of Adrb3 1 10 0.47 3.44 3.07
166 INT99419 Regulation of Drd3 1 7 0.48 1.89 2.81
167 INT11769 Regulation of Mptp1 1 8 0.60 6.38 2.68
168 INT20028 Positive_regulation of Gene_expression of Ghrh 2 9 0.50 1.52 2.62
169 INT29879 Positive_regulation of GGH 2 9 0.70 3.13 2.62
170 INT48887 Regulation of Sct 1 2 0.45 0.51 2.56
171 INT16773 Negative_regulation of Binding of Adarb1 1 7 0.37 0 2.48
172 INT27338 Regulation of ACHE 2 6 0.62 1.25 2.38
173 INT11943 Transcription of Chat 1 10 0.70 1.55 2.36
174 INT15201 Positive_regulation of CHRM1 1 8 0.54 2.14 2.35
175 INT1219 Regulation of Maob 1 5 0.47 0.78 2.16
176 INT57939 Negative_regulation of Gene_expression of Adora2a 2 4 0.36 0.15 2.02
177 INT83489 Binding of Htr5b 2 3 0.36 0.48 1.88
178 INT22087 Negative_regulation of DBH 1 3 0.59 1.45 1.84
179 INT46407 Binding of ATN1 1 4 0.36 5.85 1.81
180 INT32568 Positive_regulation of Localization of GGH 1 4 0.65 0.42 1.72
181 INT43542 Regulation of Localization of GGH 2 3 0.62 0.17 1.71
182 INT28317 Gene_expression of NXT1 1 12 0.14 4.57 1.66
183 INT25678 Negative_regulation of Binding of Atrn 1 3 0.17 0.16 1.53
184 INT47162 Positive_regulation of Negative_regulation of Maoa 1 2 0.45 0 1.42
185 INT31791 Regulation of Nrtim1 1 3 0.07 0.57 1.37
186 INT121136 Negative_regulation of DDC 1 4 0.57 2.98 1.32
187 INT63532 Positive_regulation of Positive_regulation of Ppt1 1 2 0.67 0 1.29
188 INT80887 Negative_regulation of Regulation of ADCY1 1 3 0.35 0.1 1.26
189 INT91595 Regulation of Gene_expression of Adora2a 2 1 0.52 0 1.19
190 INT82483 Negative_regulation of Positive_regulation of Tac1 1 3 0.47 0 1.06
191 INT83491 Positive_regulation of Negative_regulation of Htr5b 1 1 0.34 0.33 1.01
192 INT29885 Gene_expression of GGH 1 13 0.67 12.77 0.96
193 INT2425 Negative_regulation of Ret 1 3 0.58 1.77 0.94
194 INT7867 Regulation of Negative_regulation of Gh 1 5 0.33 1.92 0.87
195 INT29884 Positive_regulation of Gene_expression of GGH 1 2 0.47 0.08 0.87
196 INT83490 Regulation of Binding of Htr5b 1 1 0.20 0.13 0.83
197 INT149604 Regulation of Negative_regulation of AVP 1 2 0.44 0.49 0.77
198 INT62863 Localization of AP-5 1 1 0.24 0 0.76
199 INT20851 Regulation of Adra1d 1 2 0.42 0.4 0.73
200 INT25696 Negative_regulation of PSMG3 1 1 0.00 0.43 0.7
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