J:J. Neurosci. Res.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 4 0.66 2.96 4.15
2 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 4 0.51 1.79 3.22
3 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 2 0.72 1.54 2.16
4 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 2 0.68 1.43 2
5 INT69556 Slc7a11 Regulation of Cpe 2 1 0.06 0.46 1.95
6 INT116092 TFF2 Positive_regulation of NFKB1 1 1 0.17 0.06 1.77
7 INT142899 Chn1 Negative_regulation of Positive_regulation of NOS1 1 1 0.01 1.07 1.75
8 INT116093 OPRM1 Positive_regulation of Positive_regulation of NFKB1 1 1 0.36 0.08 1.56
9 INT116094 Binding of TACR1 and TFF2 1 1 0.06 0 1.47
10 INT92430 LOC681261 Positive_regulation of Ean2 1 2 0.01 1.52 1.41
11 INT130786 Positive_regulation of Oprm1 Positive_regulation of Arc 1 1 0.27 0.9 1.31
12 INT145407 Oprd1 Regulation of Positive_regulation of Dbi 1 1 0.17 0 1.07
13 INT145408 H2-Ab1 Negative_regulation of Gene_expression of Dbi 1 1 0.05 0 1.06
14 INT12373 SCN5A Negative_regulation of Cpe 1 1 0.00 0 0.94
15 INT129003 Ccl2 Positive_regulation of ANTXRL 1 1 0.00 0.68 0.92
16 INT61317 Positive_regulation of Oprd1 Positive_regulation of Gene_expression of Coq10a 1 1 0.01 0.39 0.91
17 INT129004 Cxcl1 Positive_regulation of ANTXRL 1 1 0.00 0.68 0.91
18 INT108811 Esr2 Positive_regulation of Binding of Oprm1 1 1 0.46 0.44 0.79
19 INT108812 Esr1 Positive_regulation of Positive_regulation of Oprm1 1 1 0.42 0.38 0.78
20 INT140312 Oprm1 Regulation of Gene_expression of Penk 1 1 0.07 0.26 0.77
21 INT95560 Binding of Msr1 and Zfp940 1 1 0.00 0.24 0.66
22 INT72146 POMC Positive_regulation of Phosphorylation of MYOT 1 1 0.00 0.25 0.65
23 INT95559 Msr1 Negative_regulation of Binding of Zfp940 1 1 0.00 0.23 0.59
24 INT142882 IGF1 Positive_regulation of Gene_expression of TRPV1 1 2 0.06 0.57 0.52
25 INT142881 SGCG Positive_regulation of TRPV1 1 2 0.47 0.54 0.44
26 INT4975 Binding of ITIH4 and MAG 1 4 0.44 2.24 0.39
27 INT128934 Il1b Positive_regulation of Transcription of Ptger4 1 1 0.00 0 0.29
28 INT128933 Il1b Positive_regulation of Gene_expression of Ptger4 1 1 0.00 0 0.29
29 INT142885 Positive_regulation of IGF1 Positive_regulation of TRPV1 1 1 0.04 0.24 0.29
30 INT128932 Il1b Positive_regulation of Gene_expression of Ptger2 1 1 0.00 0 0.28
31 INT142884 IGF1 Positive_regulation of TRPV1 1 1 0.04 0.24 0.28
32 INT113141 Mapk7 Regulation of Gene_expression of Fos 1 1 0.62 0.26 0.23
33 INT142883 SGCG Positive_regulation of Gene_expression of TRPV1 1 1 0.32 0.27 0.21
34 INT73332 IL1B Positive_regulation of Transcription of PTGS2 1 1 0.44 0.54 0.18
35 INT127503 Mpz Positive_regulation of Ptgs1 1 1 0.14 0.9 0.18
36 INT73331 PTAFR Positive_regulation of Transcription of PTGS2 1 1 0.13 0.54 0.18
37 INT86551 Ppm1f Positive_regulation of Camk1g 1 1 0.49 0 0.13
38 INT25269 Hmmr Negative_regulation of Npr1 1 1 0.01 0.63 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 41 3083 0.78 894.43 1639.02
2 INT2542 Localization of Calca 20 2008 0.81 518.3 1408.65
3 INT796 Gene_expression of Penk 7 1902 0.78 275.47 1057.59
4 INT6483 Gene_expression of TNF 1 3152 0.78 2515.62 929.82
5 INT7114 Positive_regulation of Ltp 5 1192 0.62 290.76 755.77
6 INT1912 Gene_expression of Calca 10 1152 0.78 453.25 739.84
7 INT5202 Positive_regulation of Gene_expression of Fos 9 1163 0.70 319.28 684
8 INT292 Localization of Penk 5 876 0.81 88.44 669.14
9 INT728 Positive_regulation of Penk 2 1068 0.70 186.9 636.87
10 INT2543 Positive_regulation of Calca 7 787 0.70 331.13 592.08
11 INT797 Regulation of Penk 1 812 0.62 111.13 542.24
12 INT5228 Positive_regulation of Fos 2 934 0.70 209.8 503.87
13 INT1045 Localization of LH 2 1211 0.81 87.04 456.25
14 INT50058 Negative_regulation of Cpox 6 907 0.58 426.28 428.29
15 INT4758 Positive_regulation of Localization of Calca 10 557 0.70 138.55 411.04
16 INT5895 Gene_expression of Oprm1 4 525 0.78 120.67 407.29
17 INT1395 Negative_regulation of Penk 2 537 0.59 87.33 389.81
18 INT6056 Negative_regulation of Gene_expression of Fos 19 601 0.59 193.05 386.84
19 INT2540 Negative_regulation of Calca 3 538 0.59 172.11 384.38
20 INT18357 Gene_expression of TRPV1 5 825 0.78 307.11 382.81
21 INT6580 Negative_regulation of Ptgs1 2 929 0.59 381.53 376.26
22 INT5660 Binding of Oprd1 2 477 0.48 71.86 342.06
23 INT5979 Gene_expression of Oprd1 2 428 0.78 75.64 320.32
24 INT5540 Positive_regulation of Oprm1 5 344 0.70 76.77 319.71
25 INT5680 Gene_expression of Ngf 6 530 0.78 264.29 310.56
26 INT4941 Positive_regulation of Oprd1 3 345 0.70 74.26 304.41
27 INT11624 Gene_expression of OPRM1 3 445 0.78 72.36 294.36
28 INT9158 Gene_expression of Tnf 2 722 0.78 522.01 277.68
29 INT9381 Positive_regulation of TRPV1 2 523 0.70 187.4 276.05
30 INT94450 Gene_expression of Nav1 8 359 0.78 131.85 275.46
31 INT1396 Binding of Penk 3 355 0.48 22.79 269.65
32 INT5591 Regulation of Gene_expression of Fos 12 425 0.62 129.06 265.78
33 INT2909 Positive_regulation of Abat 1 334 0.70 62.1 256.43
34 INT11377 Positive_regulation of Ngf 3 331 0.70 206.5 238
35 INT4759 Negative_regulation of Localization of Calca 5 294 0.59 82.62 226.45
36 INT9987 Gene_expression of Abat 1 296 0.78 95.46 226.34
37 INT6406 Binding of Oprm1 8 280 0.48 40.54 226.26
38 INT1212 Binding of Oprl1 1 312 0.48 28.6 225.15
39 INT11009 Phosphorylation of Creb1 2 458 0.82 111.34 221.97
40 INT6293 Gene_expression of Oprm1 5 312 0.78 48.73 215.61
41 INT4893 Gene_expression of Tacr1 3 366 0.78 129.67 213.92
42 INT16259 Positive_regulation of Bdnf 1 336 0.70 183.48 209.82
43 INT9132 Negative_regulation of Prkcg 1 279 0.59 88.05 203.47
44 INT798 Positive_regulation of Gene_expression of Penk 1 394 0.70 78.53 203.07
45 INT2085 Positive_regulation of LH 1 441 0.70 60.15 191.02
46 INT63934 Phosphorylation of Ephb1 3 377 0.82 150.52 188.66
47 INT24326 Gene_expression of Ngf 4 346 0.78 218.67 184.71
48 INT10194 Positive_regulation of IL6 1 702 0.70 600.62 183.38
49 INT4803 Transcription of Penk 2 435 0.72 59.09 182.4
50 INT12602 Negative_regulation of Oprm1 1 190 0.59 36.11 177.85
51 INT7506 Negative_regulation of Ltp 1 267 0.46 91.01 176.8
52 INT1429 Gene_expression of PDYN 2 308 0.78 61.33 175.65
53 INT4768 Positive_regulation of OPRM1 1 212 0.70 31.09 164.28
54 INT51921 Gene_expression of Cpox 1 501 0.73 229.81 157.81
55 INT21185 Binding of Ptprg 5 213 0.47 13.49 157.75
56 INT768 Positive_regulation of Oprl1 5 179 0.70 40.05 156.93
57 INT1303 Negative_regulation of Npr1 3 278 0.55 35.1 156.78
58 INT4740 Gene_expression of Th 1 298 0.78 61.27 154.03
59 INT1044 Negative_regulation of Localization of LH 1 358 0.59 25.95 151.31
60 INT49134 Gene_expression of Grin1 2 270 0.78 84.78 148.61
61 INT6108 Gene_expression of Npy 4 292 0.78 110.65 148.21
62 INT13353 Positive_regulation of Tnf 1 332 0.70 248.75 148.1
63 INT1033 Positive_regulation of Ca2 1 507 0.68 131.76 147.64
64 INT2379 Positive_regulation of Localization of LH 1 349 0.70 27.86 144.53
65 INT48895 Gene_expression of Il10 8 333 0.78 221.2 138.52
66 INT1047 Negative_regulation of LH 1 314 0.59 53.71 135.89
67 INT11012 Positive_regulation of Creb1 5 258 0.70 84.4 132
68 INT5380 Positive_regulation of Gene_expression of Fos 2 243 0.70 105.65 131.05
69 INT1614 Gene_expression of Oprl1 5 164 0.78 31.43 127.74
70 INT5842 Gene_expression of Gfap 1 372 0.78 153.71 127.71
71 INT6822 Gene_expression of Pdyn 1 215 0.78 35.99 125.76
72 INT4259 Positive_regulation of Npr1 3 262 0.70 49.37 123.11
73 INT2106 Regulation of Localization of LH 1 279 0.62 22.37 122.77
74 INT7341 Positive_regulation of Grin1 2 169 0.70 65.86 118.38
75 INT48593 Positive_regulation of NOS1 2 420 0.68 226.15 114.71
76 INT49651 Gene_expression of Creb1 3 276 0.78 114.77 111.96
77 INT65731 Gene_expression of Cnr1 1 234 0.78 63.82 109.34
78 INT5283 Positive_regulation of Npy 4 191 0.70 66.77 109.2
79 INT8413 Gene_expression of Ptgs1 1 248 0.78 110.17 108.58
80 INT4936 Localization of Tacr1 1 125 0.80 35.7 107.7
81 INT7627 Negative_regulation of Positive_regulation of Ltp 1 162 0.50 41.2 106.27
82 INT82878 Gene_expression of Ccl2 4 201 0.78 164.95 101.35
83 INT293 Protein_catabolism of Penk 2 161 1.00 11.71 98.45
84 INT4822 Localization of Ca2 1 417 0.80 99.57 96.45
85 INT48767 Negative_regulation of NOS1 1 312 0.59 154.25 90.32
86 INT1635 Gene_expression of Vip 4 245 0.78 53.36 88.13
87 INT15898 Positive_regulation of Prkaca 2 199 0.70 50.89 87.54
88 INT54571 Positive_regulation of NFKB1 6 263 0.70 138.99 87.32
89 INT4798 Gene_expression of Nts 1 169 0.77 29.56 86.04
90 INT21793 Positive_regulation of Ngf 2 154 0.70 94.78 85.27
91 INT73340 Negative_regulation of Faah 1 134 0.59 38.67 85.03
92 INT4857 Regulation of Tacr1 1 115 0.62 39.01 84.52
93 INT16254 Positive_regulation of Gene_expression of Ngf 4 144 0.70 80.61 82.08
94 INT5590 Negative_regulation of Fos 1 144 0.59 40.94 81.98
95 INT8650 Gene_expression of Gal 1 152 0.78 61.97 81.72
96 INT2289 Gene_expression of PENK 2 203 0.78 55.62 79.49
97 INT13036 Positive_regulation of Positive_regulation of Ltp 1 105 0.51 23.71 77.66
98 INT9382 Regulation of TRPV1 2 149 0.62 53.99 77.46
99 INT12536 Localization of Prkcg 1 101 0.80 36.37 73.81
100 INT10274 Positive_regulation of Il1b 1 123 0.70 79.76 73.56
101 INT79506 Gene_expression of Grin2b 2 122 0.78 43.71 73.42
102 INT63936 Positive_regulation of Phosphorylation of Ephb1 2 131 0.70 49.38 73.16
103 INT9236 Regulation of Gene_expression of TNF 1 204 0.62 162.66 72.99
104 INT10359 Gene_expression of Ifng 3 159 0.78 79.6 72.14
105 INT5852 Gene_expression of Penk 1 167 0.78 44.44 71.13
106 INT49995 Positive_regulation of Gene_expression of Tnf 2 187 0.70 125.07 70.54
107 INT13276 Regulation of Ltp 1 107 0.53 30.78 69.13
108 INT7134 Localization of KNG1 1 127 0.79 65.73 67.97
109 INT4637 Binding of Adarb1 1 132 0.41 14.48 67.76
110 INT55224 Gene_expression of DRGX 1 99 0.31 67.55 67.63
111 INT8388 Positive_regulation of Vip 3 142 0.70 39.72 67.61
112 INT5374 Gene_expression of Esr1 1 412 0.77 263.89 67.34
113 INT65733 Positive_regulation of Cnr1 1 125 0.70 40.27 67.33
114 INT1425 Gene_expression of Rbm39 1 143 0.58 51.32 65.44
115 INT24989 Positive_regulation of Cfp 1 125 0.61 29.55 64.9
116 INT65730 Gene_expression of Cnr2 1 129 0.78 60.15 63.1
117 INT217 Negative_regulation of Th 1 134 0.59 26.83 62.63
118 INT3950 Gene_expression of Ptger2 4 293 0.77 122.28 62.42
119 INT8363 Localization of Nts 1 135 0.81 14.29 61.71
120 INT11318 Gene_expression of Gtf3a 1 274 0.52 183.82 60.89
121 INT1430 Regulation of PDYN 2 88 0.60 16.99 60.32
122 INT4760 Negative_regulation of Gene_expression of Calca 1 93 0.59 34.19 60.3
123 INT14740 Gene_expression of TGFB1 3 272 0.78 168.48 60.18
124 INT48891 Positive_regulation of Il10 3 143 0.70 101.42 56.72
125 INT1510 Binding of PDYN 1 94 0.48 4.68 56.44
126 INT1200 Negative_regulation of Ins1 1 274 0.58 155.17 56.14
127 INT31186 Negative_regulation of Insrr 1 81 0.37 24.91 55.94
128 INT2421 Positive_regulation of Positive_regulation of Penk 1 97 0.69 13.38 55.32
129 INT37219 Gene_expression of TACR1 5 56 0.78 32.4 54.16
130 INT84495 Positive_regulation of Positive_regulation of Ephb1 3 85 0.70 46.12 54.11
131 INT1486 Negative_regulation of Cpe 1 85 0.59 28.78 54.08
132 INT8700 Positive_regulation of Positive_regulation of Calca 1 56 0.67 21.69 53.66
133 INT5759 Positive_regulation of Ptgs1 1 127 0.69 53.45 53.04
134 INT1487 Regulation of Cpe 2 68 0.62 10.24 52.91
135 INT61873 Gene_expression of Arc 6 128 0.78 128.25 52.24
136 INT27954 Positive_regulation of Gene_expression of Ngf 3 87 0.70 57.91 51.96
137 INT5338 Regulation of Npy 1 92 0.62 25.54 51.24
138 INT6165 Gene_expression of Adarb1 2 85 0.58 18.39 51.03
139 INT7287 Positive_regulation of Transcription of Penk 1 103 0.70 19.81 50.37
140 INT6796 Positive_regulation of Jun 2 165 0.70 37.18 49.64
141 INT2323 Gene_expression of Trh 1 146 0.78 29.92 49.5
142 INT12471 Regulation of Insrr 1 52 0.35 17.8 48.31
143 INT51627 Gene_expression of Grin2a 2 82 0.76 25.09 47.6
144 INT111051 Negative_regulation of Nav1 3 64 0.59 25.51 47.27
145 INT5337 Negative_regulation of Npy 1 87 0.59 19.6 46.75
146 INT6823 Negative_regulation of Pdyn 1 68 0.58 13.95 46.12
147 INT42980 Gene_expression of GAD1 2 139 0.69 94.77 45.11
148 INT3361 Positive_regulation of Esr1 2 273 0.69 208.53 44.81
149 INT63383 Binding of Cnr1 1 77 0.48 22.28 44.61
150 INT17561 Localization of Car2 1 303 0.79 60.95 44.52
151 INT5214 Localization of Cpe 1 49 0.73 13.3 44.36
152 INT989 Negative_regulation of Trh 1 90 0.59 15.45 43.63
153 INT108726 Binding of Mors1 1 38 0.33 7.08 43.62
154 INT66383 Phosphorylation of Prkaca 1 143 0.80 30.85 43.38
155 INT7828 Positive_regulation of Oprd1 1 55 0.69 14.11 42.86
156 INT1295 Binding of Pomc 1 85 0.48 12.92 42.8
157 INT82883 Positive_regulation of Ccl2 1 105 0.69 84.96 42.27
158 INT9372 Negative_regulation of Lbp 3 86 0.58 46.54 41.71
159 INT66532 Positive_regulation of Pnoc 1 46 0.70 14.99 41.39
160 INT350 Localization of Th 2 79 0.80 10.26 41.17
161 INT4887 Gene_expression of Tac4 2 70 0.77 11.66 40.97
162 INT66867 Gene_expression of Ceacam3 2 58 0.67 30.44 40.7
163 INT16261 Transcription of Bdnf 1 101 0.72 49.41 40.64
164 INT7029 Regulation of Pdyn 2 51 0.61 12.89 40.34
165 INT16194 Binding of CNR1 1 82 0.48 20.75 39.59
166 INT2429 Negative_regulation of Mpo 1 128 0.59 93.76 39.57
167 INT92517 Gene_expression of Grin1 1 105 0.78 29.53 39.43
168 INT11560 Positive_regulation of CASP3 1 236 0.70 184.33 39.38
169 INT103261 Positive_regulation of Nav1 1 68 0.70 24.25 39.27
170 INT30817 Gene_expression of Th 1 142 0.76 33.56 38.12
171 INT77307 Gene_expression of Bcl2 1 399 0.77 319.77 38
172 INT5039 Positive_regulation of Gal 1 67 0.68 27.97 37.36
173 INT82054 Positive_regulation of Grin2b 1 56 0.70 17.45 37.14
174 INT12608 Regulation of CNR1 1 62 0.60 24.36 36.02
175 INT13501 Binding of Drd2 1 65 0.48 23.76 35.6
176 INT48896 Positive_regulation of Gene_expression of Il10 2 73 0.70 43.14 35.5
177 INT111052 Positive_regulation of Gene_expression of Nav1 1 44 0.70 18.98 35.28
178 INT6484 Binding of IL1B 1 122 0.47 75.84 35.07
179 INT4892 Positive_regulation of Gene_expression of Tacr1 1 56 0.69 25.64 34.69
180 INT66005 Regulation of Cnr1 1 47 0.61 19.21 34.52
181 INT946 Negative_regulation of Nts 1 60 0.57 4.61 34.44
182 INT103262 Localization of Nav1 3 53 0.81 19.23 34.44
183 INT34465 Regulation of Oprd1 2 34 0.45 7.14 34.29
184 INT12537 Positive_regulation of Localization of Prkcg 1 36 0.70 14.57 33.81
185 INT11325 Gene_expression of HLA-E 3 209 0.76 98.05 33.72
186 INT666 Gene_expression of Jun 1 124 0.78 54.61 33.67
187 INT48907 Positive_regulation of Gene_expression of Oprm1 4 53 0.69 8.55 33.52
188 INT8784 Negative_regulation of Positive_regulation of Calca 1 40 0.59 14.67 33.49
189 INT63933 Negative_regulation of Positive_regulation of Ephb1 1 53 0.58 22.83 33.43
190 INT21560 Positive_regulation of Binding of Oprm1 5 30 0.50 7.16 32.95
191 INT6302 Binding of IFNA1 1 196 0.48 133.85 32.73
192 INT57024 Regulation of Gene_expression of Grin1 2 32 0.62 9.77 32.6
193 INT89055 Phosphorylation of Prkaca 1 60 0.61 13.41 32.49
194 INT84170 Positive_regulation of Gene_expression of Ccl2 4 58 0.69 48.79 32.43
195 INT7787 Positive_regulation of Akr1d1 1 52 0.66 3.55 31.71
196 INT610 Regulation of PENK 2 47 0.62 14.17 31.55
197 INT47764 Binding of Jun 2 106 0.48 22.62 31.39
198 INT12397 Gene_expression of Oprd1 1 53 0.78 9.1 31.31
199 INT86780 Positive_regulation of Hmox1 1 145 0.70 117.09 31.18
200 INT10285 Binding of ADRA1D 1 102 0.47 25.82 31.11
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