J:J. Orthop. Res.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT169877 Negative_regulation of Ngf Negative_regulation of Gene_expression of Calca 1 1 0.40 0.09 0.55
2 INT157602 Binding of COL1A1 and COL3A1 1 1 0.04 0 0.13

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT1912 Gene_expression of Calca 5 1152 0.78 453.25 739.84
2 INT97367 Gene_expression of Nav1 1 243 0.78 132.97 286.66
3 INT68684 Gene_expression of VEGFA 22 2371 0.78 1742.52 259.2
4 INT6665 Gene_expression of FOS 2 520 0.77 165.31 217.66
5 INT5010 Gene_expression of Calca 6 197 0.78 85.76 118.75
6 INT17546 Negative_regulation of Ngf 2 135 0.59 60.28 77.19
7 INT79494 Positive_regulation of Gene_expression of VEGFA 4 577 0.70 442.94 69.73
8 INT5374 Gene_expression of Esr1 1 412 0.77 263.89 67.34
9 INT97368 Negative_regulation of Nav1 1 62 0.59 41.56 60.27
10 INT14740 Gene_expression of TGFB1 8 272 0.78 168.48 60.18
11 INT48901 Negative_regulation of IL6 1 186 0.57 136.33 57.87
12 INT33567 Gene_expression of CALM1 1 139 0.67 48.85 56.14
13 INT83199 Gene_expression of Nos3 3 193 0.78 100.72 51.57
14 INT8690 Localization of Tac1 1 71 0.80 22.98 50.75
15 INT53083 Gene_expression of Ptgs2 1 153 0.78 90.04 50.39
16 INT26500 Gene_expression of MMP2 2 201 0.78 110.57 46.9
17 INT80124 Negative_regulation of VEGFA 1 450 0.58 311.19 44.53
18 INT117675 Transcription of Nav1 4 46 0.72 30.23 44.01
19 INT29496 Gene_expression of MMP3 1 136 0.75 49.49 41.78
20 INT28265 Positive_regulation of Calca 1 62 0.70 29.1 41.17
21 INT5793 Binding of CTS 1 110 0.48 63.91 40.62
22 INT99688 Negative_regulation of Gene_expression of VEGFA 1 274 0.58 201.8 31.1
23 INT22499 Regulation of Calca 1 42 0.62 17.32 28.02
24 INT5923 Negative_regulation of Rtn4 1 50 0.36 24.19 27.2
25 INT129956 Gene_expression of MMP13 1 145 0.72 60.48 26.98
26 INT93717 Gene_expression of Mmp3 1 85 0.78 33.95 24.89
27 INT14556 Positive_regulation of Igf1 1 105 0.69 52.21 24.04
28 INT14733 Positive_regulation of Gene_expression of TGFB1 2 71 0.69 49.89 22.2
29 INT117674 Regulation of Gene_expression of Nav1 1 16 0.62 11.5 22.01
30 INT11893 Positive_regulation of Ptger2 1 96 0.69 31.49 21.92
31 INT68683 Regulation of Gene_expression of VEGFA 3 143 0.62 104.19 20.14
32 INT27018 Gene_expression of PTGER1 3 68 0.75 31.76 20.12
33 INT51055 Positive_regulation of TIMP1 1 103 0.69 50.07 19.86
34 INT93663 Positive_regulation of MMP1 4 72 0.67 33.38 19.86
35 INT46016 Gene_expression of Ngfr 3 69 0.77 41.22 19.8
36 INT28951 Negative_regulation of IGF1 1 133 0.59 75.77 18.9
37 INT56239 Positive_regulation of Rtn4 1 20 0.26 14.05 18.8
38 INT26314 Positive_regulation of MMP3 2 48 0.67 22.14 16.17
39 INT8634 Gene_expression of Nfasc 2 23 0.68 9.16 14.96
40 INT95427 Positive_regulation of Mmp3 1 39 0.70 15.28 13.36
41 INT39046 Positive_regulation of PTGER1 1 28 0.69 18.18 13.21
42 INT123779 Positive_regulation of MMP13 1 42 0.65 24.3 12.45
43 INT48335 Negative_regulation of NOSTRIN 1 38 0.56 16.22 12.05
44 INT66038 Positive_regulation of Ngfr 1 32 0.69 26.07 11.75
45 INT101203 Negative_regulation of Gene_expression of Calca 5 12 0.59 7.06 10.72
46 INT3366 Localization of PLEK 3 44 0.78 15.83 9.55
47 INT54834 Gene_expression of Col2a1 1 48 0.72 13.5 9.41
48 INT129962 Positive_regulation of Gene_expression of MMP13 1 41 0.65 20.74 8.54
49 INT17024 Gene_expression of COL1A2 6 69 0.77 36.38 8.29
50 INT113671 Negative_regulation of Mmp3 4 26 0.49 6.33 7.88
51 INT91527 Gene_expression of CTSK 1 38 0.78 22.21 7.42
52 INT29556 Negative_regulation of CALM1 1 26 0.57 9.08 6.04
53 INT55655 Gene_expression of DCN 3 17 0.75 7.98 5.98
54 INT141146 Gene_expression of Mmp13 3 18 0.38 8.61 5.54
55 INT75546 Transcription of Rtn4 4 1 0.06 2.87 5.03
56 INT62291 Gene_expression of PTGES2 1 14 0.68 8.34 4.75
57 INT102237 Positive_regulation of Gene_expression of MMP3 1 22 0.44 7.77 4.71
58 INT19965 Positive_regulation of COL1A1 1 23 0.45 14.49 4.38
59 INT89103 Regulation of Gene_expression of TGFB1 2 15 0.56 8.11 4.37
60 INT144051 Positive_regulation of Gene_expression of PTGER1 1 11 0.12 4.46 3.97
61 INT121171 Negative_regulation of Gene_expression of Ngfr 2 6 0.58 3.46 3.89
62 INT123883 Positive_regulation of Gene_expression of Mmp3 1 16 0.60 4.42 3.74
63 INT100295 Gene_expression of Bmp7 2 27 0.78 14.34 3.3
64 INT156148 Gene_expression of CTGF 7 16 0.78 9.98 2.87
65 INT163962 Regulation of Transcription of Nav1 1 2 0.35 3.25 2.63
66 INT68091 Localization of COL1A1 2 19 0.66 9.13 2.56
67 INT151309 Positive_regulation of Positive_regulation of MMP3 1 5 0.60 2.62 2.5
68 INT85878 Negative_regulation of Il12a 1 4 0.58 2.88 2.21
69 INT89519 Negative_regulation of COL1A2 1 10 0.36 6.26 2.17
70 INT62290 Positive_regulation of Gene_expression of PTGES2 1 5 0.28 3.14 1.88
71 INT141147 Negative_regulation of Gene_expression of Mmp13 2 5 0.12 1.37 1.59
72 INT128699 Regulation of Il12a 3 3 0.45 3.36 1.59
73 INT163594 Regulation of Ngfr 1 5 0.43 2.55 1.53
74 INT102989 Regulation of Gene_expression of MMP3 2 10 0.53 3.29 1.47
75 INT165538 Binding of Bmp7 2 5 0.37 1.87 1.39
76 INT101104 Positive_regulation of Gene_expression of COL1A2 1 12 0.69 5.87 1.09
77 INT163963 Negative_regulation of Transcription of Rtn4 1 1 0.03 0.45 1.06
78 INT163595 Positive_regulation of Regulation of Ngfr 1 1 0.46 0.57 1.04
79 INT133102 Negative_regulation of Gene_expression of COL1A2 2 8 0.08 2.56 1.02
80 INT155867 Transcription of COL1A2 2 8 0.69 2.9 0.94
81 INT164079 Regulation of Gene_expression of CTGF 3 4 0.44 2 0.9
82 INT11066 Negative_regulation of NPR1 1 5 0.27 0.89 0.88
83 INT150097 Regulation of Positive_regulation of Mmp3 1 2 0.31 0.54 0.86
84 INT145306 Gene_expression of Sox9 1 5 0.54 2.47 0.8
85 INT156544 Regulation of Il12b 1 2 0.44 1.29 0.66
86 INT144922 Gene_expression of TGFBR1 3 4 0.72 0.19 0.57
87 INT165537 Negative_regulation of Bmp7 1 2 0.43 0.55 0.52
88 INT150095 Regulation of Positive_regulation of TIMP1 1 2 0.44 0.76 0.41
89 INT155865 Positive_regulation of Transcription of COL1A2 1 2 0.46 0.6 0.34
90 INT19249 Localization of TAL1 2 4 0.56 0.78 0.31
91 INT157605 Localization of COL3A1 1 3 0.80 0.55 0.29
92 INT164080 Negative_regulation of Gene_expression of CTGF 1 1 0.41 0.51 0.29
93 INT62292 Positive_regulation of PTGES2 1 2 0.02 0.51 0.27
94 INT130853 Transcription of DCN 2 2 0.67 0.42 0.26
95 INT155866 Positive_regulation of Gene_expression of DCN 1 2 0.49 2.91 0.22
96 INT157603 Positive_regulation of Gene_expression of Mmp13 1 3 0.16 0.91 0.21
97 INT169875 Negative_regulation of Ercc1 2 3 0.43 3.07 0.17
98 INT169876 Negative_regulation of Ercc4 1 1 0.42 1.34 0.08
99 INT149437 Positive_regulation of ORAI1 1 1 0.02 0.15 0.07
100 INT149439 Negative_regulation of ORAI1 1 2 0.26 0.13 0.06
101 INT149438 Gene_expression of ORAI1 1 2 0.47 0 0
102 INT144920 Positive_regulation of Gene_expression of TGFBR1 2 1 0.65 0 0
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