J:J. Pathol.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT122163 Binding of TNF and TNFRSF1B 6 1 0.44 6.06 2.41
2 INT148704 Binding of TNF and TNFRSF1A 5 1 0.44 3.3 2.09
3 INT64117 Binding of Edn1 and Ins1 1 1 0.06 0.85 0.71
4 INT148381 UFM1 Positive_regulation of JAG1 1 1 0.00 1.13 0.63
5 INT148379 UFM1 Positive_regulation of DLL1 1 1 0.00 1.13 0.63
6 INT148377 PDP1 Positive_regulation of NOTCH1 1 1 0.44 0.64 0.44
7 INT148378 CP Positive_regulation of NOTCH1 1 1 0.11 0.64 0.44
8 INT148380 PDP1 Positive_regulation of Positive_regulation of CP 1 1 0.12 0.64 0.44
9 INT71904 Binding of ESR1 and PGR 6 1 0.34 3.79 0.27
10 INT14869 Binding of EGF and TGFB3 1 1 0.14 0.69 0.19

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT1912 Gene_expression of Calca 1 1152 0.78 453.25 739.84
2 INT2543 Positive_regulation of Calca 1 787 0.70 331.13 592.08
3 INT2649 Regulation of Calca 1 433 0.62 146.05 330.95
4 INT5680 Gene_expression of Ngf 8 530 0.78 264.29 310.56
5 INT49750 Negative_regulation of CPOX 2 735 0.58 360.06 274.19
6 INT6852 Localization of TNF 1 883 0.81 705.95 270.84
7 INT68684 Gene_expression of VEGFA 7 2371 0.78 1742.52 259.2
8 INT16868 Gene_expression of Il6 1 807 0.78 499.48 256.57
9 INT11377 Positive_regulation of Ngf 3 331 0.70 206.5 238
10 INT50670 Gene_expression of CPOX 14 763 0.76 442.13 195.02
11 INT6488 Gene_expression of Tnf 3 484 0.78 339.61 191.58
12 INT49441 Negative_regulation of Cpox 2 494 0.59 303.22 177.46
13 INT1429 Gene_expression of PDYN 2 308 0.78 61.33 175.65
14 INT3300 Positive_regulation of Gene_expression of Calca 1 179 0.70 77.76 144.2
15 INT49439 Gene_expression of Cpox 2 508 0.73 326.97 130.17
16 INT50674 Gene_expression of PTGS2 2 459 0.78 253.33 118.51
17 INT7327 Regulation of Th 1 164 0.62 29.67 110.14
18 INT3038 Gene_expression of INS 3 1583 0.78 1174.16 107.01
19 INT940 Negative_regulation of Ptgs1 1 219 0.59 104.34 95.97
20 INT16254 Positive_regulation of Gene_expression of Ngf 1 144 0.70 80.61 82.08
21 INT68682 Positive_regulation of VEGFA 1 640 0.70 454.14 81.65
22 INT79494 Positive_regulation of Gene_expression of VEGFA 3 577 0.70 442.94 69.73
23 INT6486 Positive_regulation of Tnf 1 168 0.70 123.47 66.05
24 INT822 Gene_expression of ESR1 3 529 0.78 302.16 63.64
25 INT3950 Gene_expression of Ptger2 1 293 0.77 122.28 62.42
26 INT6761 Binding of CALCA 2 100 0.48 26.71 62.05
27 INT9196 Gene_expression of PTGS1 5 215 0.77 96.99 60.5
28 INT1430 Regulation of PDYN 1 88 0.60 16.99 60.32
29 INT50672 Positive_regulation of CPOX 10 205 0.44 125.93 60.06
30 INT6623 Gene_expression of NA 5 231 0.78 45.78 59.36
31 INT4241 Regulation of CALCA 1 87 0.62 28.19 55.29
32 INT8490 Negative_regulation of CALCA 5 87 0.59 29.73 51.34
33 INT66029 Negative_regulation of Tnf 5 100 0.59 84.28 48.16
34 INT26500 Gene_expression of MMP2 2 201 0.78 110.57 46.9
35 INT5781 Gene_expression of Edn1 5 190 0.78 99.1 46
36 INT19078 Binding of Ngf 1 78 0.48 31.03 44.33
37 INT30 Gene_expression of Gast 1 158 0.78 99 41.45
38 INT55135 Positive_regulation of Gene_expression of PTGS2 1 137 0.70 80.32 38.46
39 INT50673 Positive_regulation of Gene_expression of CPOX 3 156 0.54 97.31 37.03
40 INT9082 Positive_regulation of ESR1 2 238 0.69 148.51 36.69
41 INT64171 Regulation of CPOX 1 109 0.36 55.36 32.96
42 INT48693 Regulation of VEGFA 1 268 0.62 191.88 31.52
43 INT651 Positive_regulation of PTGS1 3 93 0.69 37.27 29.18
44 INT8097 Gene_expression of EGF 8 122 0.77 75.94 28.47
45 INT48202 Gene_expression of Tgfb1 1 146 0.78 89.93 27.76
46 INT55737 Positive_regulation of MMP2 1 101 0.68 59.11 27.71
47 INT9647 Gene_expression of PROC 1 163 0.65 89.76 26.75
48 INT20462 Binding of ESR1 1 210 0.44 102.7 26.34
49 INT11159 Gene_expression of EGFR 5 698 0.78 548.93 25.69
50 INT9886 Gene_expression of Ptgs1 1 92 0.77 40.66 25.31
51 INT22708 Gene_expression of MUC1 19 297 0.78 232.71 24.19
52 INT4465 Gene_expression of CEL 1 116 0.77 98.35 23.58
53 INT64175 Negative_regulation of Gene_expression of CPOX 1 66 0.38 39.64 23.07
54 INT48312 Gene_expression of NTRK1 2 72 0.78 38.21 22.24
55 INT11157 Binding of EGF 1 88 0.48 53.73 21.25
56 INT3593 Gene_expression of ADRA1D 2 70 0.75 29.48 20.87
57 INT53575 Regulation of Gene_expression of Tnf 2 46 0.62 34.35 20.63
58 INT86751 Negative_regulation of Il10 2 62 0.59 40.1 20.51
59 INT68683 Regulation of Gene_expression of VEGFA 1 143 0.62 104.19 20.14
60 INT6848 Gene_expression of BDKRB2 2 40 0.75 17.19 20.04
61 INT49922 Positive_regulation of Positive_regulation of Ngf 2 21 0.67 14.46 17.68
62 INT899 Gene_expression of F13A1 1 122 0.70 78.02 16.26
63 INT1214 Gene_expression of PGE 2 70 0.72 29.07 16.22
64 INT11335 Regulation of Ptger2 1 46 0.51 22.3 15.42
65 INT2383 Positive_regulation of CP 1 33 0.67 25.41 15.38
66 INT26501 Positive_regulation of Gene_expression of MMP2 1 51 0.67 39 15.16
67 INT69743 Gene_expression of Hmox2 1 36 0.78 20.77 14.26
68 INT6365 Localization of Edn1 1 56 0.81 18.84 13.83
69 INT50671 Regulation of Gene_expression of CPOX 1 45 0.54 30.99 13.83
70 INT4053 Regulation of GRP 2 27 0.58 5.57 13.76
71 INT20632 Gene_expression of TNC 7 72 0.78 30.43 13.16
72 INT27242 Gene_expression of PGR 3 153 0.75 98.77 12.79
73 INT48203 Positive_regulation of Tgfb1 1 67 0.70 41.31 11.07
74 INT74272 Localization of CPOX 1 39 0.63 25.12 10.53
75 INT37896 Positive_regulation of Gene_expression of PTGS1 2 37 0.67 17.28 9.27
76 INT76405 Positive_regulation of Hmox2 1 21 0.43 12.77 8.99
77 INT82743 Gene_expression of SPINK1 1 48 0.78 44.28 8.77
78 INT36798 Gene_expression of Mki67 1 178 0.77 132 8.24
79 INT10899 Positive_regulation of Gene_expression of Edn1 2 32 0.70 24.88 7.65
80 INT26462 Gene_expression of DNAH8 5 44 0.78 19.36 7.31
81 INT49751 Negative_regulation of Positive_regulation of PTGS1 1 12 0.45 4.73 7.23
82 INT61120 Positive_regulation of Gene_expression of Tgfb1 1 34 0.70 21.15 6.93
83 INT12924 Negative_regulation of Gene_expression of NA 2 25 0.30 6.59 6.71
84 INT39116 Regulation of Gene_expression of Ptger2 1 29 0.51 10.25 6.46
85 INT11154 Binding of EGFR 1 149 0.48 96.23 6.29
86 INT24042 Gene_expression of MUC5AC 4 98 0.77 74.99 6.18
87 INT77427 Regulation of Negative_regulation of CPOX 1 17 0.26 10.03 6.15
88 INT15132 Gene_expression of TNFRSF1A 1 33 0.75 20.09 5.93
89 INT148384 Positive_regulation of HEY1 2 19 0.43 29.76 5.89
90 INT49440 Localization of Cpox 1 27 0.53 11.26 5.79
91 INT64176 Transcription of CPOX 1 35 0.41 15.1 5.5
92 INT59891 Positive_regulation of GSTK1 2 46 0.67 17.66 5.33
93 INT6476 Gene_expression of TNFRSF1B 1 21 0.67 18.22 5.25
94 INT67868 Negative_regulation of Gene_expression of Tgfb1 1 18 0.43 14.27 5.16
95 INT3647 Positive_regulation of Gene_expression of F13A1 1 20 0.41 15.71 5.02
96 INT11447 Positive_regulation of DECR1 1 9 0.67 3.12 4.94
97 INT11158 Positive_regulation of Gene_expression of EGFR 2 165 0.70 131.26 4.93
98 INT122165 Binding of TNFRSF1B 1 8 0.28 7.46 4.87
99 INT2144 Localization of COL7A1 1 36 0.74 20.92 4.67
100 INT69966 Positive_regulation of Negative_regulation of CPOX 1 11 0.45 6.18 4.64
101 INT68369 Transcription of TNC 3 13 0.72 8.69 4.42
102 INT57642 Gene_expression of PCSK1 1 26 0.76 5.09 4.28
103 INT4134 Negative_regulation of Glce 2 11 0.58 2.97 4.28
104 INT57645 Gene_expression of GSTK1 1 54 0.62 21.05 4.2
105 INT15375 Gene_expression of AXL 1 21 0.65 18.5 3.74
106 INT122323 Positive_regulation of NOTCH1 4 36 0.70 35.63 3.7
107 INT23886 Positive_regulation of Gene_expression of NA 1 15 0.40 3.69 3.59
108 INT8096 Positive_regulation of Gene_expression of EGF 2 21 0.69 13.43 3.47
109 INT79270 Gene_expression of MKI67 1 113 0.77 63.52 3.38
110 INT60541 Regulation of GSTK1 1 12 0.61 6.76 3.31
111 INT10353 Positive_regulation of PGR 2 34 0.70 21.84 3.28
112 INT14872 Gene_expression of TGFB3 2 15 0.55 12.45 2.96
113 INT78798 Regulation of LUM 1 2 0.60 2.56 2.87
114 INT8095 Gene_expression of ERBB3 4 47 0.77 24.85 2.82
115 INT74983 Transcription of NA 1 9 0.41 1.71 2.79
116 INT95105 Gene_expression of TGFBR2 3 15 0.64 16.36 2.74
117 INT26705 Transcription of ADRA1D 1 6 0.67 3.99 2.74
118 INT128928 Gene_expression of Hspb2 9 15 0.76 9.42 2.52
119 INT81314 Regulation of Gene_expression of NA 1 10 0.27 4.53 2.45
120 INT132315 Positive_regulation of DLL1 1 6 0.67 3.4 2.45
121 INT82737 Regulation of Hmox2 1 7 0.14 4.6 2.44
122 INT131456 Negative_regulation of MMRN1 1 14 0.19 9.49 2.29
123 INT36314 Gene_expression of FGFR3 2 11 0.73 6.21 2.23
124 INT100622 Localization of CD68 2 16 0.73 6.58 2.2
125 INT100620 Localization of VIM 1 8 0.76 5.47 2.16
126 INT68496 Binding of PGR 1 26 0.48 16.36 2.09
127 INT67190 Gene_expression of Muc2 7 24 0.78 18.8 2.08
128 INT126374 Gene_expression of Gli3 1 6 0.77 3.67 2.02
129 INT59302 Positive_regulation of POR 1 19 0.49 15.18 1.95
130 INT148705 Binding of TNFRSF1A 1 8 0.38 5.19 1.81
131 INT105148 Positive_regulation of Gene_expression of TNC 1 6 0.50 6.45 1.8
132 INT21788 Positive_regulation of ERBB2 1 49 0.66 28.88 1.68
133 INT81982 Gene_expression of Bmpr2 1 36 0.60 14.58 1.55
134 INT120071 Negative_regulation of Positive_regulation of Tgfb1 1 4 0.16 4.06 1.55
135 INT117033 Gene_expression of JAG1 1 13 0.65 11.46 1.52
136 INT101196 Localization of LUM 1 3 0.73 1.56 1.48
137 INT131457 Gene_expression of FCGR1A 2 11 0.75 4.88 1.45
138 INT130098 Negative_regulation of NOTCH1 1 11 0.42 5.45 1.33
139 INT133255 Gene_expression of Anxa2 4 8 0.41 8.52 1.3
140 INT120698 Negative_regulation of Gene_expression of DNAH8 1 10 0.11 3.2 1.29
141 INT100621 Localization of HLA-DRA 1 7 0.40 2.86 1.2
142 INT60542 Positive_regulation of Gene_expression of GSTK1 1 11 0.39 6.21 1.13
143 INT120696 Gene_expression of SCNN1G 4 9 0.43 5.46 1.03
144 INT71906 Regulation of Gene_expression of ESR1 1 22 0.41 11.01 0.98
145 INT50454 Regulation of Gene_expression of DNAH8 1 6 0.44 2.56 0.97
146 INT11160 Regulation of Gene_expression of EGFR 1 27 0.62 22.05 0.96
147 INT120697 Negative_regulation of SCNN1G 1 6 0.32 3.53 0.92
148 INT67191 Gene_expression of Muc3 9 11 0.29 9.93 0.91
149 INT128929 Regulation of Gene_expression of Hspb2 1 2 0.60 1.14 0.9
150 INT4187 Gene_expression of Glce 1 2 0.67 1.16 0.89
151 INT68447 Positive_regulation of PDP1 1 11 0.64 5.69 0.83
152 INT60543 Positive_regulation of CYP2A 1 3 0.40 1.85 0.8
153 INT14871 Binding of TGFB3 1 3 0.13 1.2 0.78
154 INT127432 Gene_expression of Nup62 5 20 0.71 11.01 0.71
155 INT126376 Gene_expression of Gli1 1 8 0.68 4.52 0.7
156 INT32087 Regulation of Lrrc23 1 2 0.13 0.34 0.66
157 INT148382 Positive_regulation of JAG1 1 5 0.23 3.88 0.63
158 INT148386 Negative_regulation of ABI3BP 1 1 0.02 1.16 0.63
159 INT148385 Positive_regulation of HEY2 1 1 0.38 1.09 0.62
160 INT148387 Positive_regulation of NOTCH3 1 1 0.55 1.23 0.61
161 INT148383 Positive_regulation of ABI3BP 1 1 0.03 1.17 0.6
162 INT128927 Positive_regulation of Gene_expression of Hspb2 4 6 0.68 5.09 0.57
163 INT65919 Gene_expression of Ptch1 1 11 0.75 6.47 0.56
164 INT99909 Regulation of Positive_regulation of CPOX 1 2 0.35 1.88 0.53
165 INT60540 Positive_regulation of CYP26A1 1 1 0.35 2.94 0.46
166 INT82742 Gene_expression of Tff2 2 3 0.75 7.06 0.44
167 INT84756 Gene_expression of LUM 4 2 0.65 4.51 0.43
168 INT36797 Regulation of Mki67 1 13 0.24 8.76 0.3
169 INT21789 Positive_regulation of ERBB3 1 7 0.47 4.26 0.29
170 INT14873 Positive_regulation of Gene_expression of TGFB3 1 2 0.25 1.14 0.29
171 INT82741 Gene_expression of Tff1 2 3 0.75 1.43 0.27
172 INT11156 Gene_expression of TGFA 2 4 0.61 3.03 0.26
173 INT100623 Localization of ACTA2 1 2 0.27 2.97 0.25
174 INT11155 Binding of TGFA 2 2 0.34 0.95 0.23
175 INT120694 Negative_regulation of Gene_expression of SCNN1G 2 3 0.32 2.08 0.19
176 INT101195 Transcription of LUM 2 1 0.52 2.21 0.19
177 INT21787 Gene_expression of POLR1A 1 1 0.65 0.53 0.16
178 INT21786 Positive_regulation of Gene_expression of POLR1A 1 1 0.49 0.53 0.16
179 INT14870 Positive_regulation of Gene_expression of TGFA 1 2 0.46 2.12 0.15
180 INT8094 Positive_regulation of Gene_expression of BDKRB2 2 1 0.12 1.02 0.15
181 INT71905 Regulation of Gene_expression of PGR 1 6 0.50 1.3 0.14
182 INT8098 Positive_regulation of Gene_expression of ERBB3 1 7 0.69 3.79 0.1
183 INT8099 Binding of ERBB3 1 7 0.36 3.09 0.08
184 INT127433 Negative_regulation of Gene_expression of Nup62 1 2 0.53 2.36 0.08
185 INT120695 Regulation of Gene_expression of SCNN1G 1 1 0.22 0.77 0.08
186 INT126375 Negative_regulation of Gene_expression of Gli3 1 1 0.58 0.79 0.08
187 INT133256 Transcription of Anxa2 2 1 0.04 1.5 0.07
188 INT133260 Binding of LARGE 1 2 0.36 0.44 0
189 INT101194 Negative_regulation of Transcription of LUM 1 1 0.29 0.76 0
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