J:J Angiogenes Res

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT299311 Binding of RPTOR and RICTOR 1 3 0.38 0.21 1.4
2 INT299281 Binding of RPTOR and MAPKAP1 1 2 0.23 0.21 1.3
3 INT299299 VEGFA Positive_regulation of SRC 1 4 0.20 0.91 1.2
4 INT173059 Binding of KDR and VEGFA 43 6 0.43 29.63 1.1
5 INT299282 PTPN3 Negative_regulation of Positive_regulation of RPTOR 1 2 0.07 0.48 0.67
6 INT299286 VEGFA Positive_regulation of PI3 1 2 0.16 0.46 0.6
7 INT299263 PTPN3 Negative_regulation of VEGFA Positive_regulation of SRC 1 1 0.03 0.35 0.57
8 INT299288 AKT1 Positive_regulation of RPTOR 1 2 0.34 0.05 0.36
9 INT287380 Binding of VEGFA and Kdr 12 3 0.18 11.97 0.34
10 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 1 0.39 5.18 0.3
11 INT299307 AKT1 Positive_regulation of Positive_regulation of AKT1S1 1 1 0.10 0 0.3
12 INT299289 AKT1 Positive_regulation of Positive_regulation of TSC2 1 1 0.17 0 0.3
13 INT299956 Binding of PPARA and EPC1 1 1 0.09 0.34 0.29
14 INT299310 RPTOR Positive_regulation of AKT1 1 1 0.30 0 0.12
15 INT299955 Binding of KDR and FTSJ3 1 1 0.04 1.07 0.09
16 INT299953 Binding of CD34 and FTSJ3 1 1 0.04 1.07 0.09
17 INT279286 Binding of TXK and VEGFA 3 1 0.05 2.35 0.07
18 INT299291 Negative_regulation of PTPN3 Positive_regulation of Phosphorylation of SRC 1 1 0.07 0.12 0.07
19 INT299264 PTPN3 Negative_regulation of VEGFA Positive_regulation of PI3 1 1 0.03 0.12 0.05
20 INT299302 Negative_regulation of RPTOR Regulation of AKT1 1 1 0.30 0.1 0.05
21 INT299954 Negative_regulation of LXN Negative_regulation of FTSJ3 1 1 0.00 0.75 0.05
22 INT299304 RPTOR Regulation of AKT1 1 1 0.19 0.1 0.05
23 INT279284 TXK Regulation of KDR 3 1 0.05 2.22 0.04
24 INT329648 Flt1 Positive_regulation of Positive_regulation of VEGFA 1 1 0.03 0.58 0
25 INT329641 Rrm2 Regulation of Ear11 1 1 0.01 0.49 0
26 INT329642 Rrm2 Regulation of Eefsec 1 1 0.04 0.42 0
27 INT299312 VEGFA Positive_regulation of QPCT 1 1 0.02 0 0
28 INT299303 SRC Regulation of Phosphorylation of VEGFA 1 1 0.12 0.05 0
29 INT329646 Binding of VEGFA and Vegfa 1 2 0.05 0.97 0
30 INT299305 VEGFA Positive_regulation of Positive_regulation of SRC 1 1 0.22 0 0
31 INT329653 Binding of VEGFA and Ear11 1 1 0.00 0.63 0
32 INT329649 Binding of VEGFA and Rrm2 1 3 0.02 2.39 0
33 INT299300 SRC Positive_regulation of Phosphorylation of AKT1 1 1 0.24 0 0
34 INT299309 VEGFA Positive_regulation of Positive_regulation of PI3 1 1 0.18 0 0
35 INT299292 RPTOR Negative_regulation of PI3 1 1 0.25 0 0
36 INT299296 SRC Regulation of RPTOR 1 1 0.32 0 0
37 INT299306 Binding of QPCT and RICTOR 1 1 0.02 0 0
38 INT299285 SRC Regulation of Gene_expression of QPCT 1 1 0.03 0 0
39 INT329650 Binding of VEGFA and Gtf3a 1 1 0.00 0.91 0
40 INT320824 VEGFA Positive_regulation of DLL4 1 1 0.40 0.41 0
41 INT299308 SRC Regulation of PI3 1 1 0.20 0 0
42 INT299295 OR3A4P Negative_regulation of Phosphorylation of AKT1 1 1 0.00 0.22 0
43 INT299284 RICTOR Negative_regulation of PI3 1 1 0.18 0 0
44 INT299280 VEGFA Positive_regulation of RPTOR 1 1 0.29 0 0
45 INT299298 SRC Negative_regulation of PI3 1 1 0.19 0 0
46 INT299279 AKT1 Negative_regulation of PI3 1 1 0.08 0 0
47 INT329647 VEGFA Positive_regulation of Tchh 1 2 0.02 0.98 0
48 INT299283 Binding of VEGFA and RPTOR 1 1 0.19 0 0
49 INT329645 Galnt5 Positive_regulation of Tchh 1 4 0.01 1.9 0
50 INT299301 VEGFA Positive_regulation of Positive_regulation of QPCT 1 1 0.02 0 0
51 INT329651 Rrm2 Regulation of Galnt5 Positive_regulation of Tchh 1 1 0.00 0.42 0
52 INT320825 VEGFA Positive_regulation of Gene_expression of DLL4 1 1 0.40 0.41 0
53 INT299294 SRC Regulation of VEGFA 1 1 0.20 0 0
54 INT299287 Binding of VEGFA and QPCT 1 1 0.02 0 0
55 INT299290 Binding of VEGFA and RICTOR 1 1 0.16 0 0
56 INT329652 Galnt5 Positive_regulation of Galnt5 Positive_regulation of Gpt 1 1 0.00 0.54 0
57 INT299293 Binding of QPCT and RPTOR 1 1 0.02 0 0
58 INT329644 Galnt5 Positive_regulation of Gpt 1 1 0.01 0.54 0
59 INT329643 Regulation of Galnt5 Positive_regulation of Gpt 1 1 0.01 0.54 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 1 3152 0.78 2515.62 929.82
2 INT9238 Gene_expression of IL6 2 1575 0.78 1135.66 424.22
3 INT5235 Negative_regulation of TNF 1 924 0.59 772.91 331.98
4 INT5059 Positive_regulation of TNF 1 1050 0.70 896.51 322.81
5 INT68684 Gene_expression of VEGFA 28 2371 0.78 1742.52 259.2
6 INT48955 Gene_expression of Nos2 3 753 0.78 403.87 208.08
7 INT10194 Positive_regulation of IL6 1 702 0.70 600.62 183.38
8 INT9852 Positive_regulation of Gpt 1 563 0.70 364.64 146.82
9 INT4658 Binding of OPRM1 1 188 0.48 25.96 136.24
10 INT48953 Positive_regulation of Nos2 2 486 0.70 239.85 131.87
11 INT17612 Gene_expression of CRP 1 676 0.78 580.61 119.03
12 INT62124 Gene_expression of NOS1 14 444 0.78 218.08 114.85
13 INT48593 Positive_regulation of NOS1 1 420 0.68 226.15 114.71
14 INT12082 Localization of IL6 1 365 0.81 241.78 105.78
15 INT82878 Gene_expression of Ccl2 2 201 0.78 164.95 101.35
16 INT1639 Negative_regulation of OPRM1 1 107 0.59 13.86 90.37
17 INT48767 Negative_regulation of NOS1 2 312 0.59 154.25 90.32
18 INT48406 Gene_expression of Icam1 4 277 0.78 238.28 81.71
19 INT68682 Positive_regulation of VEGFA 12 640 0.70 454.14 81.65
20 INT1724 Negative_regulation of ACE 1 437 0.59 315.64 74.48
21 INT79494 Positive_regulation of Gene_expression of VEGFA 5 577 0.70 442.94 69.73
22 INT4960 Positive_regulation of CSF2 1 285 0.70 256.73 65.73
23 INT11937 Localization of Il6 2 228 0.81 139.83 64.39
24 INT17564 Gene_expression of Gpt 2 322 0.75 208.51 60.36
25 INT9234 Negative_regulation of Gene_expression of IL6 2 171 0.59 101.61 53.15
26 INT62543 Gene_expression of Icam1 1 231 0.78 187.58 52.71
27 INT83199 Gene_expression of Nos3 7 193 0.78 100.72 51.57
28 INT80124 Negative_regulation of VEGFA 12 450 0.58 311.19 44.53
29 INT49105 Gene_expression of Vcam1 4 157 0.78 157.27 43.01
30 INT82883 Positive_regulation of Ccl2 1 105 0.69 84.96 42.27
31 INT101992 Localization of VEGFA 5 413 0.81 258.23 36.15
32 INT88318 Gene_expression of CXCR4 1 208 0.77 189.67 31.72
33 INT48693 Regulation of VEGFA 4 268 0.62 191.88 31.52
34 INT99688 Negative_regulation of Gene_expression of VEGFA 9 274 0.58 201.8 31.1
35 INT64113 Positive_regulation of Gene_expression of NOS1 1 110 0.60 71.03 29.72
36 INT61953 Transcription of Nos2 2 101 0.72 46.64 25.49
37 INT48766 Regulation of NOS1 1 73 0.61 37.01 24.59
38 INT69322 Negative_regulation of MAPK14 1 70 0.54 42.92 22.71
39 INT48692 Binding of VEGFA 9 345 0.48 210.3 21.31
40 INT89396 Phosphorylation of AKT1 12 225 0.82 111.66 19.61
41 INT86187 Positive_regulation of AKT1 9 199 0.69 122.13 19.44
42 INT84171 Negative_regulation of Gene_expression of Ccl2 2 30 0.58 26.37 18.28
43 INT83198 Positive_regulation of Nos3 1 78 0.64 35.69 17.71
44 INT1533 Negative_regulation of AGT 1 105 0.42 46.54 16.92
45 INT97245 Gene_expression of AKT1 2 217 0.77 119.63 15.59
46 INT24670 Gene_expression of FGF2 4 121 0.78 85.64 15.12
47 INT109535 Gene_expression of Vegfa 1 116 0.75 84.61 14.89
48 INT105387 Gene_expression of HIF1A 3 116 0.77 98.62 14.66
49 INT103096 Regulation of PPARA 1 113 0.60 62.47 14.57
50 INT17565 Regulation of Gpt 1 85 0.60 43.64 13.68
51 INT3623 Negative_regulation of CTSB 1 49 0.55 27.39 13.52
52 INT60764 Positive_regulation of PPIG 1 39 0.67 17.08 13.48
53 INT1148 Positive_regulation of ecs 2 38 0.48 25.27 13.1
54 INT83200 Positive_regulation of Gene_expression of Nos3 1 48 0.70 24.75 12.99
55 INT89395 Negative_regulation of AKT1 2 127 0.58 70.27 12.54
56 INT27268 Localization of Gtf3a 1 71 0.21 56.93 12.51
57 INT83201 Gene_expression of NOS3 1 93 0.78 47.16 12.48
58 INT90909 Negative_regulation of Gene_expression of NOS1 1 44 0.55 23.83 12.47
59 INT24876 Gene_expression of CD34 3 172 0.78 91.02 12.39
60 INT69029 Gene_expression of PTPRC 1 127 0.75 74.26 11.57
61 INT134625 Gene_expression of Kdr 1 116 0.71 53.13 10.09
62 INT80110 Regulation of Positive_regulation of TNF 1 34 0.44 25.79 9.78
63 INT62166 Positive_regulation of Gene_expression of Gpt 1 64 0.50 39.13 9.69
64 INT70134 Negative_regulation of TXK 1 124 0.23 81.96 9.59
65 INT1118 Gene_expression of C6orf25 1 73 0.77 47.24 9.1
66 INT69264 Gene_expression of KIT 4 207 0.78 179.41 8.95
67 INT4651 Gene_expression of Cebpz 1 39 0.00 20.19 8.5
68 INT48908 Transcription of NOS1 2 27 0.55 13.46 8.39
69 INT1150 Gene_expression of ecs 4 42 0.59 29.38 7.73
70 INT49104 Positive_regulation of Gene_expression of Vcam1 2 30 0.69 36.52 7.64
71 INT103154 Gene_expression of FLT1 1 138 0.76 58.5 7.41
72 INT82610 Positive_regulation of SRC 6 53 0.67 26.89 7.27
73 INT102814 Negative_regulation of CASP3 1 46 0.43 28.54 6.94
74 INT86805 Localization of HGF 3 49 0.71 28.48 6.35
75 INT83712 Transcription of Nos3 1 19 0.69 13.09 6.31
76 INT92504 Negative_regulation of Ccl2 1 17 0.43 8.98 6.29
77 INT111545 Phosphorylation of VEGFA 7 50 0.76 22.19 5.88
78 INT22943 Positive_regulation of Positive_regulation of Gpt 1 23 0.47 16.09 5.55
79 INT82611 Negative_regulation of SRC 5 30 0.57 20.16 5.47
80 INT76313 Gene_expression of CD38 2 30 0.64 20.74 5.27
81 INT97905 Positive_regulation of FGF2 1 33 0.70 26.74 5.17
82 INT107386 Negative_regulation of AGTR1 1 37 0.55 35.94 5.15
83 INT245593 Gene_expression of PTPN3 1 32 0.38 10.68 5.09
84 INT105393 Positive_regulation of Localization of VEGFA 1 66 0.70 45.45 4.9
85 INT105336 Regulation of AKT1 1 52 0.56 32.53 4.89
86 INT99690 Negative_regulation of Positive_regulation of VEGFA 2 30 0.58 14.56 4.79
87 INT103155 Gene_expression of KDR 13 78 0.66 50.53 4.38
88 INT50581 Regulation of PPIG 1 26 0.55 8.96 4.32
89 INT7083 Positive_regulation of HBM 1 35 0.66 20.96 4.3
90 INT51898 Binding of PECAM1 1 26 0.36 18.87 4.22
91 INT109450 Positive_regulation of Phosphorylation of AKT1 5 62 0.64 25.18 4.21
92 INT156097 Negative_regulation of Localization of VEGFA 1 70 0.58 34.96 4.17
93 INT21681 Positive_regulation of CD34 2 54 0.66 33.95 4.14
94 INT34829 Positive_regulation of Gnat3 1 27 0.46 5.24 4.14
95 INT118835 Positive_regulation of Vegfa 1 18 0.59 11.2 3.91
96 INT106264 Negative_regulation of Gene_expression of Vcam1 2 13 0.53 10.47 3.55
97 INT8270 Positive_regulation of Ear11 1 8 0.60 1.74 3.42
98 INT111547 Negative_regulation of Phosphorylation of VEGFA 3 13 0.42 5.08 3.22
99 INT100688 Gene_expression of SRC 3 28 0.75 15.51 3.08
100 INT69727 Gene_expression of QPCT 5 18 0.65 5.45 3.05
101 INT89392 Negative_regulation of Positive_regulation of AKT1 2 23 0.50 15.69 3.02
102 INT105390 Positive_regulation of Gene_expression of HIF1A 1 27 0.49 26.3 2.88
103 INT45112 Positive_regulation of PRB1 1 20 0.60 6.49 2.85
104 INT89401 Negative_regulation of Phosphorylation of AKT1 3 68 0.58 35.61 2.8
105 INT101883 Regulation of Gene_expression of Nos3 1 11 0.52 6.71 2.73
106 INT11196 Negative_regulation of Gnat3 1 26 0.37 3.14 2.69
107 INT299340 Negative_regulation of RPTOR 7 1 0.53 1.68 2.6
108 INT43483 Gene_expression of DLL4 1 7 0.60 0.89 2.59
109 INT142908 Localization of FGFR1 1 18 0.38 11.46 2.57
110 INT97902 Gene_expression of AGGF1 4 17 0.11 13.45 2.51
111 INT24672 Localization of FGF2 1 27 0.71 14.59 2.48
112 INT137135 Gene_expression of THBS1 1 28 0.75 11.55 2.45
113 INT12384 Positive_regulation of PI3 2 7 0.38 5.73 2.33
114 INT134626 Positive_regulation of Gene_expression of Kdr 1 20 0.63 14.63 2.29
115 INT51461 Gene_expression of Itgb2 2 7 0.75 5.48 2.2
116 INT109327 Negative_regulation of KIT 1 42 0.57 43.2 2.15
117 INT101866 Positive_regulation of Gene_expression of AKT1 2 49 0.52 17.47 2.14
118 INT112364 Negative_regulation of HIF1A 1 22 0.57 16.95 2.13
119 INT136503 Negative_regulation of KDR 5 46 0.48 43.1 1.86
120 INT123130 Positive_regulation of Positive_regulation of AKT1 1 22 0.49 11.77 1.83
121 INT183753 Regulation of HBM 1 24 0.39 13.13 1.79
122 INT82609 Phosphorylation of SRC 4 17 0.80 6.45 1.7
123 INT16782 Binding of ERLEC1 1 15 0.10 8.23 1.7
124 INT299331 Positive_regulation of RPTOR 6 1 0.63 0.9 1.62
125 INT59901 Localization of Ear11 2 3 0.59 0.72 1.57
126 INT119048 Negative_regulation of Gene_expression of HIF1A 1 10 0.57 9.23 1.5
127 INT97900 Negative_regulation of Gene_expression of FGF2 1 9 0.57 8.37 1.48
128 INT263023 Gene_expression of PI3 2 6 0.75 2.68 1.39
129 INT167357 Positive_regulation of EPC1 10 15 0.30 9.12 1.36
130 INT299978 Regulation of FTSJ3 10 1 0.07 8.47 1.36
131 INT199567 Binding of Kdr 2 18 0.47 13.81 1.34
132 INT91863 Negative_regulation of Gene_expression of NOS3 1 13 0.51 9.43 1.34
133 INT74609 Negative_regulation of Gene_expression of Cebpz 1 5 0.38 3.14 1.3
134 INT163133 Gene_expression of ZBP1 4 28 0.65 18.59 1.25
135 INT245598 Positive_regulation of PTPN3 4 3 0.34 1.13 1.23
136 INT105270 Positive_regulation of KDR 1 25 0.49 11.49 1.2
137 INT299333 Gene_expression of RPTOR 8 1 0.61 0.25 1.18
138 INT135556 Localization of AKT1 2 38 0.69 12.78 1.17
139 INT118792 Regulation of Positive_regulation of AKT1 1 8 0.61 3.73 1.15
140 INT219950 Negative_regulation of Gene_expression of SRC 2 2 0.29 1.32 1.15
141 INT159328 Localization of EPC1 8 11 0.59 7.08 1.14
142 INT299342 Regulation of RPTOR 3 1 0.41 1.06 1.1
143 INT299966 Negative_regulation of EPC1 8 10 0.22 8.66 1.07
144 INT200556 Regulation of Kdr 1 8 0.28 6.04 1.01
145 INT112717 Negative_regulation of Binding of VEGFA 1 21 0.56 11.07 0.99
146 INT299964 Positive_regulation of FTSJ3 13 1 0.08 7.32 0.98
147 INT299967 Negative_regulation of FTSJ3 13 1 0.07 11.72 0.97
148 INT230251 Binding of FKBP1A 1 6 0.28 2.24 0.94
149 INT108477 Gene_expression of Ear11 1 3 0.44 0.86 0.93
150 INT85135 Gene_expression of CDCP1 1 14 0.02 5.1 0.84
151 INT299350 Phosphorylation of RPTOR 6 1 0.75 0.26 0.82
152 INT173100 Binding of KDR 3 39 0.39 22.48 0.81
153 INT118004 Positive_regulation of Gene_expression of SRC 1 13 0.49 11.05 0.8
154 INT121858 Negative_regulation of PI3 1 7 0.43 3.16 0.8
155 INT299316 Binding of FIBP 1 2 0.01 1.36 0.78
156 INT299981 Gene_expression of FTSJ3 5 6 0.09 3.08 0.74
157 INT246524 Binding of QPCT 1 4 0.05 3.65 0.72
158 INT7723 Localization of Hgf 1 10 0.46 6.28 0.68
159 INT299338 Negative_regulation of Regulation of AKT1 1 2 0.31 2.32 0.68
160 INT252054 Phosphorylation of TSC2 1 4 0.80 0.63 0.67
161 INT299324 Positive_regulation of QPCT 2 3 0.09 0.12 0.64
162 INT174868 Regulation of Negative_regulation of VEGFA 1 4 0.43 4.51 0.63
163 INT299325 Negative_regulation of Gene_expression of PI3 2 1 0.24 0.35 0.63
164 INT289197 Localization of QPCT 1 3 0.15 0.53 0.62
165 INT217091 Positive_regulation of Rrm2 4 5 0.33 4.12 0.6
166 INT299980 Positive_regulation of Gene_expression of FTSJ3 3 1 0.08 1.48 0.6
167 INT142184 Regulation of TXK 1 10 0.11 8.25 0.59
168 INT129783 Positive_regulation of Gene_expression of KIT 1 16 0.50 18.12 0.58
169 INT94713 Regulation of CD34 1 11 0.45 8.02 0.58
170 INT128472 Negative_regulation of CD34 1 7 0.42 3.92 0.58
171 INT203763 Localization of EGFL7 1 4 0.08 3 0.56
172 INT172964 Binding of Vegfa 1 14 0.47 10.62 0.53
173 INT299965 Regulation of EPC1 7 7 0.23 4.44 0.53
174 INT203764 Binding of EGFL7 1 6 0.05 2.84 0.53
175 INT299323 Negative_regulation of Gene_expression of QPCT 2 1 0.03 0.65 0.53
176 INT107121 Positive_regulation of Tchh 3 4 0.60 5.88 0.5
177 INT60556 Localization of Epc1 1 5 0.61 2.9 0.49
178 INT45338 Gene_expression of RICTOR 1 4 0.52 0.89 0.48
179 INT217083 Gene_expression of Rrm2 1 10 0.47 4.16 0.47
180 INT158426 Binding of NOTCH1 1 10 0.36 7.95 0.45
181 INT263820 Phosphorylation of RPS6KB1 1 6 0.52 1.43 0.42
182 INT102722 Phosphorylation of PDPK1 1 3 0.82 1.39 0.4
183 INT131773 Regulation of KDR 1 12 0.49 12.01 0.39
184 INT109329 Negative_regulation of FLT3 1 7 0.29 6.88 0.38
185 INT109328 Gene_expression of FLT3 1 6 0.61 4.78 0.37
186 INT148797 Phosphorylation of KDR 1 7 0.80 5.15 0.36
187 INT299963 Positive_regulation of Localization of EPC1 2 1 0.26 1.54 0.36
188 INT138051 Negative_regulation of Positive_regulation of SRC 1 3 0.57 0.84 0.33
189 INT221833 Positive_regulation of TSC2 1 2 0.23 0.39 0.33
190 INT238439 Positive_regulation of PDPK1 1 2 0.20 1.3 0.31
191 INT173099 Localization of AGGF1 1 2 0.01 3.26 0.29
192 INT299320 Positive_regulation of AKT1S1 1 1 0.13 0 0.29
193 INT299337 Phosphorylation of AKT1S1 1 1 0.17 0 0.29
194 INT245592 Regulation of PTPN3 1 3 0.22 0.88 0.28
195 INT299983 Localization of FTSJ3 4 1 0.09 3.24 0.28
196 INT246186 Phosphorylation of EIF4EBP1 1 5 0.46 0.42 0.27
197 INT299335 Negative_regulation of Localization of QPCT 1 1 0.03 0.47 0.27
198 INT299971 Regulation of Localization of EPC1 1 1 0.10 1.13 0.24
199 INT190735 Gene_expression of Eefsec 1 10 0.11 1.03 0.22
200 INT164162 Negative_regulation of Phosphorylation of SRC 2 3 0.29 2.12 0.21
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