J:J Cardiothorac Surg

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT329670 Csf2 Regulation of Col7a1 1 1 0.03 0.4 0.17
2 INT252575 Rpe Negative_regulation of SOD1 1 2 0.03 2.39 0.14
3 INT252571 Rpe Positive_regulation of Positive_regulation of Sdcbp 1 2 0.04 2.27 0.13
4 INT252573 Rpe Negative_regulation of Gpx1 1 2 0.07 2.34 0.13
5 INT252572 Rpe Positive_regulation of Sdcbp 1 1 0.04 1.12 0.09
6 INT344266 Binding of APOH and CD40LG 1 1 0.04 0.31 0
7 INT194264 Tnnc1 Regulation of Mb 1 1 0.00 0.16 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT9238 Gene_expression of IL6 1 1575 0.78 1135.66 424.22
2 INT6852 Localization of TNF 1 883 0.81 705.95 270.84
3 INT5972 Gene_expression of IL1B 2 948 0.78 510.91 263.97
4 INT68684 Gene_expression of VEGFA 5 2371 0.78 1742.52 259.2
5 INT11313 Positive_regulation of Il6 2 526 0.70 331.27 201.59
6 INT15516 Gene_expression of Crp 2 711 0.77 615.33 173.09
7 INT51921 Gene_expression of Cpox 2 501 0.73 229.81 157.81
8 INT120811 Gene_expression of Gopc 2 1174 0.59 428.49 150.55
9 INT15515 Positive_regulation of Crp 2 700 0.70 604.24 150.15
10 INT5116 Gene_expression of IL2 1 670 0.78 291.13 146.69
11 INT170025 Gene_expression of Fig4 1 588 0.67 183.27 113.32
12 INT69440 Gene_expression of ROS1 1 752 0.78 477.64 103.83
13 INT90091 Gene_expression of GOPC 1 967 0.67 366.22 103.6
14 INT11381 Positive_regulation of IL1B 1 330 0.70 209.31 100.9
15 INT48408 Gene_expression of ICAM1 1 494 0.78 340.08 88.6
16 INT171145 Positive_regulation of Fig4 1 274 0.59 93.55 69.81
17 INT8357 Gene_expression of KNG1 1 153 0.75 77.26 68.66
18 INT546 Binding of ALB 1 311 0.48 85.98 60.14
19 INT55344 Gene_expression of Ros1 4 396 0.54 217.64 59.98
20 INT169926 Positive_regulation of Gopc 1 416 0.46 157.8 58.67
21 INT9408 Positive_regulation of Crp 1 296 0.69 242.27 57.35
22 INT96937 Gene_expression of Mmp9 1 191 0.75 150.3 56.01
23 INT83199 Gene_expression of Nos3 2 193 0.78 100.72 51.57
24 INT4345 Gene_expression of Gtf3a 5 157 0.67 80.75 48.47
25 INT375 Positive_regulation of REN 1 293 0.70 152.46 47.55
26 INT4216 Gene_expression of CD40LG 3 328 0.78 256.02 44.23
27 INT25383 Gene_expression of Csf2 1 222 0.76 152.93 43.32
28 INT49105 Gene_expression of Vcam1 3 157 0.78 157.27 43.01
29 INT613 Gene_expression of Alb 1 268 0.78 149.84 42.78
30 INT157666 Positive_regulation of GOPC 1 335 0.60 120.19 42.75
31 INT27798 Gene_expression of Ntrk2 3 111 0.78 56.08 42.68
32 INT4004 Gene_expression of IGHG3 1 321 0.71 221.03 42.33
33 INT69437 Positive_regulation of ROS1 1 328 0.58 222.83 40.56
34 INT62827 Positive_regulation of ICAM1 1 184 0.70 180.95 36.28
35 INT53577 Negative_regulation of Localization of TNF 1 110 0.59 59.28 35.23
36 INT60710 Gene_expression of Col7a1 2 217 0.78 113.2 35.2
37 INT8905 Gene_expression of EDN1 1 215 0.78 157.1 34.19
38 INT16960 Gene_expression of Crp 1 166 0.76 116.21 34.07
39 INT9694 Positive_regulation of Csf2 8 102 0.68 70.09 33.07
40 INT62830 Gene_expression of VCAM1 1 149 0.78 125.23 32.4
41 INT48693 Regulation of VEGFA 1 268 0.62 191.88 31.52
42 INT724 Negative_regulation of Alb 1 151 0.59 93.57 29.65
43 INT28361 Gene_expression of TP53 1 443 0.78 384.86 28.8
44 INT9296 Negative_regulation of PLEK 1 100 0.57 36.65 27.52
45 INT2393 Positive_regulation of Mb 3 174 0.69 93.59 26.79
46 INT17739 Gene_expression of S100B 1 226 0.78 132.7 26.4
47 INT86295 Gene_expression of Mmp2 1 114 0.76 73.68 24.25
48 INT49196 Gene_expression of SELE 1 105 0.78 107.29 22.92
49 INT91891 Gene_expression of Kit 3 268 0.78 158.89 22.67
50 INT35711 Positive_regulation of Sdcbp 3 110 0.60 50.45 22.11
51 INT5096 Positive_regulation of Gtf3a 2 79 0.60 42.26 20.62
52 INT63340 Positive_regulation of Gene_expression of ICAM1 2 109 0.70 90.82 20.61
53 INT116282 Gene_expression of Mmp13 1 83 0.75 45.4 20.18
54 INT68683 Regulation of Gene_expression of VEGFA 1 143 0.62 104.19 20.14
55 INT49103 Positive_regulation of Vcam1 1 71 0.69 59.52 19.85
56 INT70614 Gene_expression of FAS 7 118 0.75 112.33 19.01
57 INT78024 Gene_expression of ACLY 4 73 0.75 59.15 18.54
58 INT65260 Positive_regulation of Col7a1 1 95 0.69 61.73 18.42
59 INT83198 Positive_regulation of Nos3 1 78 0.64 35.69 17.71
60 INT61513 Positive_regulation of Gpx1 2 71 0.64 37.91 17.07
61 INT899 Gene_expression of F13A1 2 122 0.70 78.02 16.26
62 INT8904 Positive_regulation of Gene_expression of EDN1 1 66 0.70 65.4 14.42
63 INT20420 Gene_expression of MYC 2 99 0.75 49.32 14.36
64 INT22276 Gene_expression of TBXA2R 1 65 0.77 23.22 14.21
65 INT37722 Gene_expression of NCAM1 1 103 0.75 81.57 14.18
66 INT59870 Gene_expression of F3 1 51 0.65 51.83 14.01
67 INT35120 Gene_expression of Sdcbp 2 68 0.67 21.33 13.96
68 INT13823 Gene_expression of Egf 1 97 0.78 39.99 12.99
69 INT31990 Positive_regulation of SOD1 3 124 0.69 67.79 12.52
70 INT12135 Gene_expression of PLEK 1 62 0.75 34.13 12.47
71 INT14510 Gene_expression of SOD1 3 208 0.76 88.56 12.4
72 INT73829 Positive_regulation of Gene_expression of VCAM1 2 41 0.61 35.96 11.92
73 INT4047 Binding of F13A1 2 105 0.43 66.54 11.81
74 INT41313 Gene_expression of Gpx1 2 68 0.78 34.24 11.77
75 INT111476 Gene_expression of TP63 1 88 0.76 61.08 11.64
76 INT20603 Positive_regulation of TNFRSF10B 1 40 0.67 32.61 11.44
77 INT25963 Gene_expression of DES 1 122 0.75 98.81 11.25
78 INT57424 Positive_regulation of TNNT1 1 42 0.67 31.84 9.7
79 INT80036 Positive_regulation of FAS 4 42 0.67 42.22 9.4
80 INT62829 Positive_regulation of VCAM1 2 39 0.70 38.42 9.15
81 INT77490 Positive_regulation of Tnnc1 2 85 0.68 43.54 9.07
82 INT102698 Binding of ACCS 1 54 0.42 66.73 9.06
83 INT25381 Localization of Csf2 2 62 0.76 47.48 9.03
84 INT6499 Localization of Ntrk2 1 44 0.79 11.78 8.75
85 INT80034 Positive_regulation of Gene_expression of FAS 2 32 0.67 30.34 8.51
86 INT6133 Negative_regulation of Serpinc1 1 56 0.58 42.8 8.35
87 INT148703 Gene_expression of NOVA2 1 73 0.65 18.05 8.3
88 INT75932 Binding of Csf2 2 45 0.37 33.2 8.01
89 INT26551 Positive_regulation of Gene_expression of KNG1 2 19 0.67 11.05 7.98
90 INT2271 Gene_expression of F2 1 51 0.76 30.21 7.97
91 INT38971 Positive_regulation of Gene_expression of Gtf3a 1 27 0.60 18.25 7.77
92 INT81399 Regulation of Vcam1 1 24 0.46 23.53 7.68
93 INT49104 Positive_regulation of Gene_expression of Vcam1 1 30 0.69 36.52 7.64
94 INT17501 Negative_regulation of F2 5 70 0.58 32.23 7.51
95 INT112183 Gene_expression of CRCP 2 10 0.67 3.34 7.47
96 INT16618 Negative_regulation of SERPING1 2 81 0.59 86.28 7.17
97 INT35584 Binding of ACLY 1 22 0.35 31.78 7.17
98 INT69439 Regulation of ROS1 1 46 0.45 31.22 6.94
99 INT78182 Positive_regulation of ACCS 2 43 0.43 46.39 6.78
100 INT43721 Gene_expression of Vegfa 4 49 0.77 36.18 6.63
101 INT2442 Localization of Mb 1 38 0.80 24.74 6.33
102 INT8683 Positive_regulation of F3 2 31 0.67 42.89 6.21
103 INT137454 Gene_expression of ADIPOQ 13 88 0.78 85.32 6.2
104 INT65265 Positive_regulation of Gene_expression of Col7a1 2 48 0.69 23.81 6.16
105 INT71727 Negative_regulation of Icam1 1 25 0.45 17.76 5.73
106 INT17056 Gene_expression of DLD 10 37 0.57 13.15 5.47
107 INT44997 Positive_regulation of Eef1a2 1 16 0.40 8.84 5.37
108 INT87420 Gene_expression of BCL2L1 1 56 0.75 48.84 5.32
109 INT62525 Positive_regulation of SELE 1 38 0.70 46 5.25
110 INT80038 Positive_regulation of Gene_expression of MYC 1 24 0.67 13.93 5.17
111 INT62832 Negative_regulation of Gene_expression of SELE 1 16 0.49 10.6 5.12
112 INT58060 Negative_regulation of HMI 1 30 0.44 11.9 5.06
113 INT11493 Positive_regulation of KLK1 1 21 0.67 9.22 5
114 INT100991 Gene_expression of HOMER1 2 12 0.67 6.96 4.98
115 INT28703 Negative_regulation of TFPI 2 29 0.38 19.81 4.93
116 INT12104 Positive_regulation of PLG 1 45 0.68 28.94 4.81
117 INT37661 Negative_regulation of SERPINC1 1 48 0.59 38.6 4.77
118 INT144481 Gene_expression of SERPING1 5 55 0.77 50.4 4.75
119 INT90852 Gene_expression of F2r 1 26 0.78 5.5 4.66
120 INT121954 Binding of Mthfr 1 17 0.44 13.47 4.66
121 INT57749 Negative_regulation of Gene_expression of TP53 1 39 0.56 36.79 4.45
122 INT9842 Binding of F2 1 36 0.47 22.79 4.42
123 INT4097 Localization of Pth 2 66 0.81 47.17 4.36
124 INT35122 Negative_regulation of Sdcbp 3 43 0.51 22.01 4.34
125 INT88278 Binding of Kit 1 33 0.37 24.45 4.13
126 INT68189 Gene_expression of TNNT1 1 27 0.75 14.87 4.03
127 INT83431 Binding of ADIPOQ 5 35 0.48 33.63 3.83
128 INT58602 Gene_expression of HMI 2 34 0.65 25.26 3.74
129 INT83433 Positive_regulation of ADIPOQ 5 40 0.69 34 3.67
130 INT18920 Binding of Egf 1 24 0.48 9.43 3.57
131 INT17685 Negative_regulation of Cog1 1 23 0.42 15.65 3.56
132 INT53584 Regulation of Gpx1 1 19 0.62 14.38 3.48
133 INT191807 Gene_expression of CD24 1 75 0.78 53.92 3.34
134 INT14397 Gene_expression of Serpinc1 1 27 0.46 14.54 3.32
135 INT51607 Positive_regulation of DES 1 33 0.67 32.24 3.29
136 INT77670 Positive_regulation of ACLY 2 24 0.49 21.68 3.12
137 INT105985 Transcription of Mmp9 1 11 0.66 8.55 3.02
138 INT81972 Positive_regulation of Dse 1 20 0.57 16.5 2.99
139 INT138141 Transcription of Mmp2 1 10 0.64 6.52 2.99
140 INT22277 Positive_regulation of Gene_expression of TBXA2R 1 13 0.69 5.95 2.92
141 INT84527 Positive_regulation of Gene_expression of F3 1 16 0.49 15.83 2.85
142 INT28891 Localization of Selp 1 13 0.60 8.23 2.83
143 INT10893 Binding of VWF 1 27 0.47 25.02 2.82
144 INT73682 Gene_expression of Pprc1 4 9 0.18 1.22 2.79
145 INT7142 Positive_regulation of DLD 3 22 0.60 7.69 2.76
146 INT26172 Gene_expression of C10orf10 1 6 0.65 1.11 2.75
147 INT61645 Negative_regulation of Gc 1 15 0.51 10.44 2.71
148 INT81411 Negative_regulation of Sele 1 8 0.38 7 2.7
149 INT43719 Positive_regulation of Vegfa 2 21 0.69 5.15 2.64
150 INT204340 Localization of ADIPOQ 1 20 0.75 25.18 2.64
151 INT96092 Binding of ANXA5 2 24 0.36 14.51 2.6
152 INT23954 Negative_regulation of Mb 1 24 0.49 11.27 2.55
153 INT156130 Binding of SERPING1 1 29 0.42 26.16 2.52
154 INT1829 Gene_expression of CFH 1 71 0.75 64.24 2.49
155 INT111451 Regulation of ADIPOQ 3 24 0.56 18.81 2.47
156 INT103603 Negative_regulation of Gene_expression of Mmp2 1 16 0.51 12.29 2.47
157 INT12618 Positive_regulation of IAPP 3 54 0.68 32.03 2.29
158 INT43723 Regulation of Vegfa 1 9 0.34 4.96 2.28
159 INT91836 Negative_regulation of Gene_expression of BCL2L1 1 9 0.49 8.59 2.25
160 INT60279 Gene_expression of VHL 2 70 0.78 75.21 2.21
161 INT183675 Negative_regulation of ETFDH 4 11 0.37 5.62 2.18
162 INT181396 Transcription of Csf2 1 15 0.48 6.38 2.17
163 INT64676 Gene_expression of ANXA5 2 11 0.75 13.48 2.11
164 INT116280 Transcription of Mmp13 2 11 0.67 6.52 2.06
165 INT121126 Positive_regulation of RNF34 1 9 0.04 6.83 2.05
166 INT93789 Gene_expression of Tnnc1 1 28 0.76 17.3 1.99
167 INT14586 Gene_expression of Cpb1 1 23 0.58 6.18 1.99
168 INT61644 Gene_expression of Gc 1 16 0.70 11.35 1.95
169 INT14182 Gene_expression of CPB1 2 26 0.67 10.06 1.9
170 INT97750 Positive_regulation of Positive_regulation of FAS 2 4 0.49 4.9 1.8
171 INT235327 Binding of Lad1 3 4 0.33 0.4 1.78
172 INT14184 Positive_regulation of CPB1 5 23 0.55 14.38 1.73
173 INT60749 Localization of IAPP 1 17 0.78 12.57 1.69
174 INT36689 Gene_expression of Bpifa2 1 27 0.50 14.92 1.65
175 INT25384 Positive_regulation of Localization of Csf2 2 11 0.66 7.81 1.62
176 INT35526 Binding of Eef1a2 2 14 0.34 5.82 1.61
177 INT159489 Positive_regulation of Positive_regulation of Csf2 2 6 0.42 6.02 1.61
178 INT27293 Regulation of SOD1 1 21 0.53 15.73 1.55
179 INT27585 Positive_regulation of smc 1 9 0.58 3.2 1.47
180 INT18844 Binding of IAPP 1 11 0.36 11.01 1.45
181 INT574 Negative_regulation of C1S 5 9 0.47 11.25 1.41
182 INT181868 Localization of ACLY 2 5 0.62 6.36 1.4
183 INT317979 Positive_regulation of Transcription of Mmp2 1 4 0.46 2.63 1.37
184 INT130773 Regulation of Gene_expression of FAS 1 5 0.37 6.87 1.32
185 INT2270 Positive_regulation of Gene_expression of F2 1 6 0.21 4.23 1.26
186 INT115108 Negative_regulation of Gene_expression of FAS 1 9 0.57 9.16 1.23
187 INT188376 Negative_regulation of Gene_expression of Vegfa 1 5 0.30 5.29 1.18
188 INT93168 Gene_expression of Ttf1 1 24 0.63 17.18 1.14
189 INT213277 Positive_regulation of Gene_expression of ADIPOQ 2 14 0.50 17.7 1.14
190 INT127363 Binding of Cpb1 2 8 0.32 2.5 1.14
191 INT160576 Gene_expression of Psgb1 1 3 0.35 1.63 1.08
192 INT169472 Gene_expression of PDIA2 1 15 0.58 7.88 0.96
193 INT14185 Regulation of CPB1 2 9 0.35 5.88 0.93
194 INT61613 Regulation of DLD 3 6 0.34 2.96 0.92
195 INT2482 Regulation of Positive_regulation of REN 1 4 0.59 2.62 0.91
196 INT24815 Binding of LDHA 1 9 0.36 6.73 0.89
197 INT144482 Negative_regulation of Gene_expression of SERPING1 1 8 0.43 6.06 0.89
198 INT134748 Positive_regulation of SV2A 1 7 0.46 2.89 0.82
199 INT202683 Localization of FAS 2 6 0.73 5.86 0.8
200 INT173422 Gene_expression of ETFDH 1 11 0.45 5.78 0.78
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