J:J Circadian Rhythms

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT190981 Binding of Npy and Scn2a1 1 2 0.10 0 1.75
2 INT190986 Per1 Positive_regulation of Scn2a1 1 1 0.17 0 0.74
3 INT190979 Per2 Positive_regulation of Scn2a1 1 1 0.20 0 0.74
4 INT190984 Binding of Scn2a1 and Gria1 1 1 0.03 0.08 0.71
5 INT190987 Abat Regulation of Scn2a1 1 1 0.03 0.07 0.59
6 INT190988 Vip Positive_regulation of Gene_expression of Scn2a1 1 2 0.16 0.1 0.57
7 INT190977 Npy Regulation of Scn2a1 1 1 0.16 0 0.4
8 INT190983 Vip Positive_regulation of Gene_expression of Per1 1 2 0.13 0.51 0.27
9 INT190978 Vip Positive_regulation of Gene_expression of Per2 1 2 0.22 0.51 0.27
10 INT190998 ADCYAP1 Positive_regulation of Scn2a1 1 1 0.07 0.45 0.27
11 INT190996 ADCYAP1 Positive_regulation of Per1 1 1 0.06 0.45 0.27
12 INT190997 ADCYAP1 Positive_regulation of Per2 1 1 0.07 0.45 0.27
13 INT190985 Vip Regulation of Scn2a1 1 1 0.09 0 0.18
14 INT190982 Avp Positive_regulation of Scn2a1 1 2 0.17 0.17 0.1
15 INT190976 Binding of Scn2a1 and Gal 1 1 0.06 0 0.05
16 INT212864 MT1A Positive_regulation of PPRC1 1 1 0.20 0 0
17 INT190980 Binding of Avp and Scn2a1 1 1 0.12 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT3439 Localization of Abat 4 1017 0.78 112.39 727.06
2 INT292 Localization of Penk 1 876 0.81 88.44 669.14
3 INT477 Localization of Avp 2 813 0.81 131.58 300.4
4 INT1902 Gene_expression of Cck 1 348 0.78 70.33 241.92
5 INT9987 Gene_expression of Abat 5 296 0.78 95.46 226.34
6 INT11009 Phosphorylation of Creb1 1 458 0.82 111.34 221.97
7 INT6665 Gene_expression of FOS 1 520 0.77 165.31 217.66
8 INT767 Localization of Gnrhr 2 565 0.80 106.68 214.57
9 INT120811 Gene_expression of Gopc 4 1174 0.59 428.49 150.55
10 INT6108 Gene_expression of Npy 2 292 0.78 110.65 148.21
11 INT1273 Gene_expression of Avp 11 356 0.78 90.56 138.7
12 INT49651 Gene_expression of Creb1 1 276 0.78 114.77 111.96
13 INT9012 Localization of Vip 4 283 0.81 31.71 106.16
14 INT90091 Gene_expression of GOPC 2 967 0.67 366.22 103.6
15 INT5940 Negative_regulation of Avp 3 236 0.59 67.86 101.2
16 INT17459 Positive_regulation of Gene_expression of FOS 1 182 0.67 53.45 96.38
17 INT48767 Negative_regulation of NOS1 2 312 0.59 154.25 90.32
18 INT1635 Gene_expression of Vip 11 245 0.78 53.36 88.13
19 INT3441 Regulation of Localization of Abat 1 117 0.38 8.67 87.59
20 INT4798 Gene_expression of Nts 1 169 0.77 29.56 86.04
21 INT8650 Gene_expression of Gal 1 152 0.78 61.97 81.72
22 INT6107 Localization of Npy 1 180 0.81 26.76 81.67
23 INT5993 Positive_regulation of Nts 1 122 0.70 26.82 70.45
24 INT2123 Positive_regulation of Gnrh1 1 209 0.70 24.2 68.97
25 INT8388 Positive_regulation of Vip 4 142 0.70 39.72 67.61
26 INT1599 Positive_regulation of ADCY1 1 146 0.67 30.05 64.9
27 INT480 Negative_regulation of Localization of Avp 1 151 0.59 27.64 63.72
28 INT169926 Positive_regulation of Gopc 1 416 0.46 157.8 58.67
29 INT5356 Positive_regulation of FOS 2 153 0.69 54.21 56.74
30 INT17458 Negative_regulation of Gene_expression of FOS 1 98 0.57 36.77 55.69
31 INT49028 Positive_regulation of Nos1 1 102 0.70 34.73 51.05
32 INT2197 Gene_expression of Gnrh1 1 184 0.78 40.04 50.57
33 INT5337 Negative_regulation of Npy 1 87 0.59 19.6 46.75
34 INT42980 Gene_expression of GAD1 1 139 0.69 94.77 45.11
35 INT88617 Positive_regulation of Gene_expression of Creb1 1 90 0.69 51.69 44.29
36 INT8835 Localization of SFTPA1 1 65 0.68 32.81 38.65
37 INT385 Gene_expression of Agt 1 182 0.78 63.62 37.91
38 INT7675 Gene_expression of ENG 1 146 0.77 45.35 34.6
39 INT14497 Gene_expression of GRP 2 82 0.78 17.67 32.27
40 INT4861 Localization of GRP 1 84 0.80 8.26 28.03
41 INT7894 Negative_regulation of Vip 1 59 0.59 11.76 27.36
42 INT74688 Regulation of Nos1 1 55 0.62 22.16 25.3
43 INT172458 Regulation of Gopc 1 155 0.53 62.57 24.86
44 INT48766 Regulation of NOS1 1 73 0.61 37.01 24.59
45 INT12424 Binding of Npy 1 48 0.48 8.23 24.26
46 INT20003 Gene_expression of Scn2a1 36 125 0.71 8.78 23.94
47 INT8836 Positive_regulation of SFTPA1 1 36 0.47 28.37 23.59
48 INT127435 Gene_expression of Per1 36 89 0.77 13.94 22.31
49 INT170444 Binding of Gopc 1 172 0.39 45.05 20.71
50 INT7470 Positive_regulation of Gene_expression of Avp 1 37 0.70 19.55 19.96
51 INT5499 Transcription of Avp 1 52 0.72 7.98 19.87
52 INT124371 Negative_regulation of Gsk3b 21 170 0.55 87.92 15.51
53 INT128319 Gene_expression of Per2 11 105 0.78 14.69 15.13
54 INT7040 Binding of Vip 2 43 0.48 4.57 15.05
55 INT124372 Gene_expression of Gsk3b 33 164 0.75 95.64 14.35
56 INT13823 Gene_expression of Egf 2 97 0.78 39.99 12.99
57 INT11141 Negative_regulation of Gene_expression of Avp 2 23 0.59 3.85 12.19
58 INT13287 Gene_expression of Cpb2 1 27 0.56 7.84 11.95
59 INT128054 Gene_expression of Per1 4 15 0.61 2.12 11.84
60 INT118755 Gene_expression of Per2 3 12 0.68 2.81 11.41
61 INT28843 Positive_regulation of Scn2a1 9 31 0.68 5.35 10.7
62 INT149818 Gene_expression of Clock 15 81 0.70 14.15 10.04
63 INT178306 Negative_regulation of Gene_expression of Gopc 1 71 0.37 26.43 9.74
64 INT135372 Positive_regulation of Gsk3b 3 72 0.70 50.03 9.28
65 INT7813 Regulation of SRI 2 25 0.61 6.18 8.13
66 INT84894 Gene_expression of Calb2 1 45 0.73 24.65 7.81
67 INT130117 Regulation of Per1 6 26 0.53 3.25 7.63
68 INT1664 Gene_expression of Kitl 1 30 0.65 13.63 7.47
69 INT17674 Localization of Scn2a1 9 32 0.61 1.73 6.79
70 INT3500 Positive_regulation of Gene_expression of Gnrh1 1 25 0.69 4.59 6.69
71 INT170385 Regulation of Clock 4 29 0.49 4.95 6.39
72 INT13352 Regulation of Kitl 1 11 0.45 3.91 6.07
73 INT128045 Positive_regulation of Per1 1 29 0.69 5.32 5.5
74 INT35248 Gene_expression of Gpi 1 14 0.51 2.38 5.49
75 INT68860 Gene_expression of Galr2 1 10 0.76 3.37 5.49
76 INT196972 Regulation of Per2 4 23 0.62 2.22 5.46
77 INT124370 Positive_regulation of Gene_expression of Gsk3b 7 47 0.67 24.56 5.4
78 INT128324 Regulation of Gene_expression of Per1 5 11 0.61 1.95 5.22
79 INT31991 Gene_expression of NTS 1 33 0.75 12.98 4.99
80 INT104760 Localization of MT1A 1 13 0.44 1.5 4.85
81 INT135374 Binding of Gsk3b 3 46 0.48 24.36 4.75
82 INT56159 Regulation of Scn2a1 8 17 0.51 3.23 4.27
83 INT139252 Negative_regulation of Per2 1 15 0.52 0.91 4.24
84 INT127434 Negative_regulation of Gene_expression of Per1 5 12 0.58 2.58 4.2
85 INT164220 Gene_expression of OPN1SW 4 21 0.65 13.7 4.14
86 INT4739 Gene_expression of Calb1 1 16 0.78 2.83 4.08
87 INT181589 Binding of OPN1SW 1 13 0.32 9.47 4.07
88 INT204020 Negative_regulation of Gene_expression of Per2 1 16 0.52 2.56 3.99
89 INT204007 Localization of Per2 1 21 0.75 1.94 3.98
90 INT190722 Positive_regulation of Gene_expression of Scn2a1 6 15 0.36 0.5 3.78
91 INT28844 Negative_regulation of Scn2a1 2 15 0.37 3.84 3.65
92 INT181588 Regulation of OPN1SW 3 14 0.39 8.32 3.59
93 INT147664 Positive_regulation of Per2 2 19 0.63 1.07 3.56
94 INT135373 Regulation of Gsk3b 3 35 0.62 18.11 3.53
95 INT118761 Positive_regulation of Per2 3 9 0.42 0.68 3.33
96 INT30131 Positive_regulation of Negative_regulation of Avp 1 5 0.50 1.94 3.3
97 INT56502 Gene_expression of Igl 3 3 0.13 0.09 3.11
98 INT135575 Gene_expression of Prok2 1 7 0.73 2.51 2.95
99 INT128328 Gene_expression of Arntl 3 44 0.74 3.77 2.63
100 INT65603 Positive_regulation of SRI 1 8 0.41 2.32 2.56
101 INT59119 Positive_regulation of ADCYAP1 1 9 0.69 4.68 2.48
102 INT204019 Negative_regulation of C2 1 10 0.26 6.23 2.44
103 INT196971 Positive_regulation of Gene_expression of Per1 4 8 0.69 1.23 2.44
104 INT92000 Gene_expression of Gsk3a 2 12 0.18 4.12 2.39
105 INT97485 Localization of ADCYAP1 2 4 0.78 0.24 2.35
106 INT80733 Binding of Scn2a1 2 11 0.30 1.09 2.3
107 INT74046 Localization of Calb2 1 12 0.80 2.05 2.24
108 INT34860 Negative_regulation of Gene_expression of Scn2a1 3 8 0.30 0.97 1.94
109 INT92776 Gene_expression of CALB1 3 5 0.29 1.89 1.94
110 INT204004 Transcription of Per2 6 30 0.72 5.05 1.91
111 INT204018 Localization of Gsk3b 1 27 0.71 13.67 1.87
112 INT104759 Positive_regulation of MT1A 1 3 0.26 0.28 1.84
113 INT170387 Transcription of Clock 2 11 0.63 1.78 1.83
114 INT128053 Positive_regulation of Per1 3 5 0.35 0.54 1.83
115 INT94524 Gene_expression of MT1A 2 6 0.39 1.66 1.75
116 INT204017 Positive_regulation of Gene_expression of Per2 3 14 0.61 2.82 1.71
117 INT49124 Protein_catabolism of Vip 1 7 0.57 0 1.63
118 INT139254 Negative_regulation of Per1 1 12 0.56 3.17 1.62
119 INT62127 Localization of SRI 1 12 0.45 10.21 1.54
120 INT79001 Positive_regulation of Localization of Scn2a1 1 3 0.36 0.22 1.48
121 INT188683 Binding of Per1 1 10 0.37 0.9 1.47
122 INT128322 Gene_expression of Cry1 4 11 0.60 1.03 1.4
123 INT169776 Gene_expression of Opn4 1 52 0.77 8.75 1.38
124 INT161182 Gene_expression of NMS 2 1 0.41 1.83 1.35
125 INT135576 Positive_regulation of Gene_expression of Prok2 1 2 0.17 0.52 1.3
126 INT116859 Regulation of NOVA2 1 15 0.44 4.62 1.25
127 INT118764 Regulation of Per2 1 2 0.16 0 1.21
128 INT148491 Negative_regulation of Map3k3 1 3 0.02 1.71 1.18
129 INT17332 Regulation of Positive_regulation of FOS 1 6 0.44 0.78 1.11
130 INT141116 Transcription of Scn2a1 3 9 0.45 1.1 1.1
131 INT190964 Regulation of Gene_expression of Scn2a1 2 7 0.29 1.29 1.02
132 INT198406 Localization of C2 1 5 0.65 1.42 1.01
133 INT79881 Positive_regulation of Aanat 2 4 0.69 2.32 1.01
134 INT204003 Binding of Per2 1 9 0.42 0.82 0.94
135 INT37300 Localization of Gpi 2 4 0.27 0.37 0.9
136 INT181587 Negative_regulation of OPN1SW 2 12 0.51 4.36 0.89
137 INT196974 Regulation of Regulation of Per1 1 2 0.34 0.52 0.87
138 INT190962 Localization of Igl 1 1 0.14 0 0.82
139 INT190971 Regulation of Gene_expression of Igl 1 1 0.09 0 0.78
140 INT204002 Negative_regulation of Gene_expression of Gsk3b 6 15 0.55 8.57 0.77
141 INT190958 Negative_regulation of Gene_expression of Calb1 1 5 0.41 2.15 0.77
142 INT118669 Binding of Cpb2 1 4 0.31 0.97 0.76
143 INT135573 Binding of Prok2 1 2 0.12 0.36 0.76
144 INT190968 Regulation of Per1 1 1 0.14 0 0.74
145 INT82780 Binding of CALB1 1 2 0.06 0 0.73
146 INT152672 Positive_regulation of Gene_expression of MT1A 1 2 0.29 0.35 0.68
147 INT204011 Phosphorylation of Per2 1 23 0.72 1.25 0.67
148 INT190961 Negative_regulation of Positive_regulation of Scn2a1 1 2 0.27 0.15 0.64
149 INT79878 Localization of Asmt 1 2 0.06 0.09 0.61
150 INT204006 Negative_regulation of Localization of Gsk3b 1 6 0.40 1.66 0.6
151 INT204005 Negative_regulation of Gene_expression of Clock 1 3 0.39 0.58 0.45
152 INT204013 Phosphorylation of Arntl 1 2 0.63 1.02 0.41
153 INT190965 Positive_regulation of Gene_expression of NMS 1 1 0.09 0.41 0.41
154 INT204012 Regulation of Negative_regulation of Gsk3b 2 4 0.42 4.51 0.39
155 INT196973 Regulation of Gene_expression of Clock 2 12 0.38 3.58 0.38
156 INT204009 Positive_regulation of Binding of Per2 1 2 0.43 0.57 0.38
157 INT190975 Regulation of Prok2 2 1 0.15 0 0.35
158 INT190936 Gene_expression of Bbaa2 1 1 0.06 0.33 0.32
159 INT204010 Regulation of Transcription of Per2 3 5 0.62 1.23 0.27
160 INT212868 Gene_expression of LIPA 2 4 0.25 0.44 0.25
161 INT204021 Transcription of Gsk3b 1 8 0.57 2.75 0.23
162 INT153133 Binding of VIPR2 1 2 0.35 0 0.21
163 INT190993 Negative_regulation of CALB1 1 2 0.10 0.46 0.21
164 INT139281 Gene_expression of VIPR2 1 3 0.74 0.88 0.2
165 INT166390 Binding of CALB2 1 3 0.36 1.57 0.17
166 INT212869 Localization of PPRC1 2 1 0.50 0.21 0.17
167 INT190974 Regulation of Gene_expression of Calb2 1 2 0.29 0.36 0.16
168 INT197764 Positive_regulation of Localization of Asmt 1 1 0.02 0.09 0.13
169 INT204015 Gene_expression of Tep1 1 2 0.51 0.5 0.09
170 INT190972 Binding of Calr 2 1 0.07 0 0.07
171 INT212866 Gene_expression of Prcs1 2 1 0.01 0.29 0.07
172 INT190969 Gene_expression of Vipr2 1 1 0.19 0 0.06
173 INT203988 Localization of Per1 2 1 0.68 0.14 0.06
174 INT197763 Positive_regulation of Positive_regulation of Aanat 1 2 0.35 0.55 0.05
175 INT192303 Negative_regulation of Nat2 1 1 0.06 0 0.04
176 INT190959 Positive_regulation of Negative_regulation of Scn2a1 1 1 0.31 0.1 0.04
177 INT190967 Positive_regulation of Gene_expression of Calb2 1 1 0.08 0 0.04
178 INT190970 Localization of Calr 1 1 0.14 0 0.03
179 INT190992 Positive_regulation of VIPR2 1 1 0.07 0 0.03
180 INT190994 Localization of CALB1 1 1 0.14 0 0.03
181 INT171513 Gene_expression of PPRC1 6 3 0.45 0.13 0
182 INT204000 Negative_regulation of Transcription of Per2 1 2 0.37 0.46 0
183 INT212865 Regulation of Prcs1 1 1 0.01 0 0
184 INT212867 Regulation of MT1A 3 1 0.23 0 0
185 INT204008 Regulation of Transcription of Clock 1 1 0.12 0.1 0
186 INT190995 Positive_regulation of CALB1 1 1 0.09 0 0
187 INT204014 Phosphorylation of Cry1 2 1 0.01 0.16 0
188 INT204016 Regulation of Tep1 1 1 0.10 0.46 0
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