J:J Hematol Oncol

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT262760 Binding of TEP1 and CD163L1 1 1 0.00 1.65 0.37
2 INT257776 Phosphorylation of AR Positive_regulation of Localization of TAB2 1 1 0.26 0.38 0.24
3 INT262751 Binding of PTCH1 and SMO 1 2 0.25 1.29 0.1
4 INT249117 Binding of Abl1 and Bcr 4 3 0.36 2.22 0.09
5 INT262758 MRGPRF Positive_regulation of Transcription of NFE2L3 1 1 0.01 1.25 0.09
6 INT262754 MRGPRF Positive_regulation of NFE2L3 1 1 0.01 1.24 0.09
7 INT262755 MRGPRF Positive_regulation of NFE2L2 1 1 0.18 1.24 0.09
8 INT244640 AGK Negative_regulation of KIT 1 1 0.00 0.69 0.08
9 INT251777 Negative_regulation of TXK Positive_regulation of PDGFA 1 1 0.04 1 0.08
10 INT244639 AGK Negative_regulation of PDGFRB 1 1 0.01 0.69 0.08
11 INT257777 INCENP Positive_regulation of AR 1 1 0.04 0.49 0.08
12 INT251773 TXK Positive_regulation of PDGFA 1 1 0.04 1 0.08
13 INT244638 AGK Negative_regulation of KDR 1 1 0.00 0.68 0.08
14 INT251775 AGK Negative_regulation of INSRR 1 1 0.00 1.1 0.07
15 INT251776 Negative_regulation of TXK Negative_regulation of ERBB4 1 1 0.04 1.07 0.06
16 INT251774 Negative_regulation of TXK Negative_regulation of EGFR 1 1 0.07 1.06 0.06
17 INT244641 PDGFA Regulation of MTOR 1 2 0.07 2.55 0.06
18 INT251778 Negative_regulation of TXK Positive_regulation of KDR 1 1 0.03 0.99 0.05
19 INT262781 Birc5 Regulation of TEP1 1 1 0.00 0.49 0.05
20 INT262780 Birc5 Regulation of CD163L1 1 1 0.00 0.49 0.05
21 INT251779 TXK Positive_regulation of KDR 1 1 0.03 0.99 0.05
22 INT262757 SMO Positive_regulation of Regulation of GLI1 1 1 0.34 0.6 0.04
23 INT176131 Binding of AKT1 and PIK3CG 2 1 0.15 1.08 0
24 INT251780 RRAD Negative_regulation of MTOR 1 1 0.00 0.62 0
25 INT297614 ZNF275 Positive_regulation of Gene_expression of TSC1 1 1 0.00 1.56 0
26 INT262750 GLYR1 Positive_regulation of THBS1 1 1 0.01 0.99 0
27 INT262759 PIK3CG Positive_regulation of MTOR 1 1 0.38 0.54 0
28 INT297613 Negative_regulation of ZNF275 Positive_regulation of Gene_expression of TSC1 1 1 0.00 1.66 0
29 INT297615 Binding of TSC1 and HDAC9 1 2 0.01 0.4 0
30 INT262752 IGHA1 Positive_regulation of IGKV2D-19 1 1 0.00 1.39 0
31 INT262756 STAT3 Positive_regulation of NFE2L2 1 1 0.31 1.55 0
32 INT262753 Binding of MTOR and PIK3CG 1 1 0.20 0.82 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT68684 Gene_expression of VEGFA 3 2371 0.78 1742.52 259.2
2 INT9852 Positive_regulation of Gpt 5 563 0.70 364.64 146.82
3 INT3038 Gene_expression of INS 2 1583 0.78 1174.16 107.01
4 INT90091 Gene_expression of GOPC 1 967 0.67 366.22 103.6
5 INT68682 Positive_regulation of VEGFA 2 640 0.70 454.14 81.65
6 INT3375 Gene_expression of IGHE 4 535 0.77 387.47 65.46
7 INT80124 Negative_regulation of VEGFA 1 450 0.58 311.19 44.53
8 INT3987 Positive_regulation of IGHE 1 316 0.70 283.2 40.16
9 INT5206 Gene_expression of AR 7 316 0.78 113.83 27.29
10 INT11159 Gene_expression of EGFR 7 698 0.78 548.93 25.69
11 INT9781 Binding of INSRR 1 64 0.31 19.1 25.2
12 INT8775 Binding of IGHE 1 167 0.48 102.61 23.54
13 INT85952 Positive_regulation of AR 4 168 0.67 64.36 20.66
14 INT89396 Phosphorylation of AKT1 1 225 0.82 111.66 19.61
15 INT18311 Positive_regulation of CD8A 3 145 0.69 113.48 19.44
16 INT712 Positive_regulation of LDHA 2 160 0.70 175.25 19.11
17 INT28215 Gene_expression of CDKN1A 1 196 0.76 113.9 18.3
18 INT133647 Negative_regulation of HDAC9 14 149 0.57 106.84 17.9
19 INT13510 Gene_expression of ERBB2 10 530 0.78 405.68 16.79
20 INT116465 Gene_expression of Birc5 2 241 0.78 192.31 15.32
21 INT75502 Positive_regulation of CDKN1A 1 123 0.68 70.75 14.74
22 INT64563 Gene_expression of UGT1A1 1 27 0.75 3.31 13.43
23 INT86383 Negative_regulation of EGFR 7 258 0.59 173.94 13.32
24 INT8210 Positive_regulation of Gene_expression of INS 1 188 0.68 146.57 12.83
25 INT27242 Gene_expression of PGR 1 153 0.75 98.77 12.79
26 INT12135 Gene_expression of PLEK 1 62 0.75 34.13 12.47
27 INT8548 Gene_expression of HP 1 86 0.77 47.62 11.94
28 INT170601 Positive_regulation of Gene_expression of GOPC 1 122 0.43 42.79 11.68
29 INT19795 Positive_regulation of EGFR 2 161 0.70 103.69 11.55
30 INT18412 Binding of PLEK 1 49 0.47 17.82 10.72
31 INT701 Localization of IGHE 1 87 0.80 40.5 10.62
32 INT35164 Negative_regulation of IGHE 1 96 0.58 76.3 9.74
33 INT57162 Positive_regulation of Gene_expression of CDKN1A 1 64 0.68 35.3 9.69
34 INT70134 Negative_regulation of TXK 5 124 0.23 81.96 9.59
35 INT49325 Gene_expression of Cd34 1 102 0.78 82.75 8.97
36 INT35366 Binding of AR 4 87 0.47 30.52 8.9
37 INT22383 Binding of IL2 1 59 0.48 39.06 8.56
38 INT10969 Positive_regulation of PLEK 2 33 0.67 16.96 8.35
39 INT53487 Gene_expression of TSC1 2 81 0.58 77.71 7.94
40 INT2971 Regulation of IGHE 2 42 0.61 28.81 7.87
41 INT1124 Negative_regulation of CD40LG 1 53 0.57 36.26 7
42 INT95117 Gene_expression of PDGFA 1 71 0.71 51.17 6.9
43 INT22024 Negative_regulation of HBG1 1 45 0.58 26 6.8
44 INT50387 Negative_regulation of AR 1 67 0.45 26.31 6.61
45 INT138833 Binding of MTHFR 1 12 0.46 16.08 6.4
46 INT192225 Gene_expression of HDAC9 1 35 0.58 32.82 6.36
47 INT38672 Binding of KRT20 1 69 0.39 48.01 6.31
48 INT11154 Binding of EGFR 2 149 0.48 96.23 6.29
49 INT75501 Gene_expression of CCND1 1 90 0.76 60.86 5.93
50 INT87470 Gene_expression of SDC1 1 27 0.78 24.86 5.81
51 INT41892 Gene_expression of HBM 1 48 0.64 28.32 5.64
52 INT125066 Negative_regulation of HDAC4 1 56 0.49 41.55 5.42
53 INT91754 Gene_expression of Cp 1 42 0.77 21.97 5.38
54 INT76313 Gene_expression of CD38 1 30 0.64 20.74 5.27
55 INT15376 Positive_regulation of Gene_expression of ERBB2 5 215 0.70 168.54 5.23
56 INT11158 Positive_regulation of Gene_expression of EGFR 2 165 0.70 131.26 4.93
57 INT116464 Negative_regulation of Birc5 3 53 0.59 45.4 4.91
58 INT12474 Regulation of INSRR 1 18 0.29 6.29 4.81
59 INT17110 Gene_expression of PSMD1 1 60 0.65 19.57 4.69
60 INT55114 Gene_expression of CRS 3 42 0.58 26.86 4.69
61 INT124375 Gene_expression of Wnt2 15 67 0.56 38.03 4.67
62 INT5205 Localization of AR 1 43 0.80 12.87 4.63
63 INT84727 Negative_regulation of Gene_expression of AR 1 38 0.58 12.46 4.63
64 INT141000 Negative_regulation of GSK 1 24 0.57 9.46 4.4
65 INT103155 Gene_expression of KDR 1 78 0.66 50.53 4.38
66 INT7083 Positive_regulation of HBM 1 35 0.66 20.96 4.3
67 INT20052 Negative_regulation of UGT1A1 1 12 0.58 4.51 4.29
68 INT10923 Positive_regulation of Lipg 1 30 0.50 22.87 4.26
69 INT86919 Negative_regulation of PIK3CG 2 40 0.57 21.16 3.97
70 INT5204 Positive_regulation of Gene_expression of AR 4 60 0.67 23.54 3.53
71 INT9999 Regulation of Gene_expression of IGHE 1 32 0.60 15.75 3.53
72 INT57252 Negative_regulation of PGR 1 22 0.43 12.95 3.33
73 INT69593 Negative_regulation of PSMD1 1 11 0.57 4.06 3.33
74 INT194625 Gene_expression of GSK 1 18 0.75 9.02 3.23
75 INT78297 Gene_expression of CD59 1 31 0.72 24.11 3.18
76 INT188047 Positive_regulation of Wnt2 4 51 0.58 31.41 2.94
77 INT12237 Positive_regulation of Lipg 6 19 0.60 11.09 2.92
78 INT4873 Positive_regulation of FCGR3A 2 21 0.49 14.35 2.89
79 INT31450 Binding of HIST1H1B 1 20 0.37 10.21 2.84
80 INT41721 Negative_regulation of MTOR 5 40 0.58 32.49 2.83
81 INT10893 Binding of VWF 1 27 0.47 25.02 2.82
82 INT89401 Negative_regulation of Phosphorylation of AKT1 1 68 0.58 35.61 2.8
83 INT121493 Gene_expression of XRCC1 1 55 0.65 73.43 2.76
84 INT116463 Negative_regulation of Gene_expression of Birc5 1 40 0.59 33.99 2.74
85 INT77925 Negative_regulation of TEP1 2 21 0.53 15.23 2.62
86 INT11235 Positive_regulation of IFNA2 1 27 0.69 15.32 2.57
87 INT31989 Binding of SOD1 1 43 0.47 19.38 2.55
88 INT1829 Gene_expression of CFH 2 71 0.75 64.24 2.49
89 INT188255 Gene_expression of DKK1 2 19 0.60 12.69 2.39
90 INT182318 Regulation of Birc5 1 25 0.60 23.58 2.29
91 INT9995 Localization of C6orf25 1 13 0.69 6.48 2.29
92 INT83236 Localization of PGR 1 14 0.73 8.26 2.23
93 INT9254 Negative_regulation of LDHA 1 23 0.43 13.3 2.2
94 INT133648 Regulation of HDAC9 1 14 0.60 10.01 2.18
95 INT109327 Negative_regulation of KIT 1 42 0.57 43.2 2.15
96 INT9908 Negative_regulation of IAPP 1 29 0.57 19.37 2.12
97 INT141833 Gene_expression of WNT1 2 14 0.75 10.57 2.1
98 INT118291 Binding of TXK 1 19 0.10 11.77 1.94
99 INT101243 Regulation of STAT3 1 12 0.62 9.98 1.92
100 INT136503 Negative_regulation of KDR 4 46 0.48 43.1 1.86
101 INT191154 Binding of HDAC9 1 20 0.36 14.12 1.83
102 INT21788 Positive_regulation of ERBB2 2 49 0.66 28.88 1.68
103 INT33393 Positive_regulation of Gene_expression of PLEK 1 9 0.67 7.35 1.65
104 INT168681 Gene_expression of BMS1 1 5 0.37 2.7 1.62
105 INT167692 Binding of NCAM1 1 11 0.36 6.73 1.59
106 INT120519 Localization of XRCC1 1 15 0.78 17.03 1.51
107 INT52962 Binding of ERBB2 3 77 0.47 50.03 1.49
108 INT167085 Negative_regulation of ERBB2 5 67 0.57 44.6 1.48
109 INT78889 Binding of UGT1A1 2 10 0.47 3.41 1.47
110 INT41719 Gene_expression of MTOR 1 27 0.77 19.43 1.44
111 INT11449 Phosphorylation of BLZF1 1 3 0.06 0.27 1.43
112 INT125320 Negative_regulation of HSP90AA1 1 20 0.45 23.93 1.42
113 INT85829 Gene_expression of CA9 1 14 0.68 12.59 1.4
114 INT134338 Gene_expression of CD55 1 23 0.65 13.01 1.38
115 INT242153 Negative_regulation of Wnt2 3 19 0.49 11.87 1.37
116 INT140296 Negative_regulation of XIAP 1 9 0.45 13.61 1.37
117 INT96838 Negative_regulation of Gene_expression of ERBB2 1 25 0.57 15.83 1.34
118 INT82932 Transcription of AR 1 14 0.67 5.75 1.34
119 INT199004 Gene_expression of ARMC9 1 43 0.58 17.72 1.32
120 INT213379 Phosphorylation of AR 1 6 0.63 2.03 1.21
121 INT123877 Negative_regulation of ABL1 7 40 0.57 27.94 1.17
122 INT133898 Binding of HSP90AA1 3 17 0.30 8.83 1.12
123 INT210392 Regulation of PDGFA 1 10 0.36 11.41 1.12
124 INT207203 Transcription of Akt1 1 6 0.67 3.73 1.1
125 INT197721 Positive_regulation of ARMC9 2 36 0.35 20.08 1.03
126 INT155696 Gene_expression of PIK3CG 2 16 0.65 8.54 1.02
127 INT116980 Positive_regulation of CCL20 1 5 0.70 4.8 1.02
128 INT124374 Binding of Wnt2 3 21 0.31 10.16 0.99
129 INT21940 Positive_regulation of CALR 1 15 0.40 17.42 0.95
130 INT197105 Negative_regulation of FLT4 1 13 0.42 11.48 0.92
131 INT200738 Gene_expression of HIST2H4A 2 7 0.18 4.65 0.91
132 INT74021 Regulation of XRCC1 1 15 0.44 16.91 0.88
133 INT242152 Transcription of Wnt2 1 8 0.57 5.22 0.88
134 INT199563 Negative_regulation of Abl1 2 38 0.46 21.5 0.87
135 INT294726 Positive_regulation of Lts1 1 5 0.49 4.06 0.87
136 INT135299 Binding of PTCH1 2 10 0.48 12.16 0.84
137 INT119102 Gene_expression of PDGFRA 1 13 0.75 11.99 0.81
138 INT188251 Localization of DKK1 3 6 0.50 3.26 0.77
139 INT199573 Gene_expression of Abl1 3 33 0.65 20.79 0.75
140 INT241499 Binding of Abl1 4 23 0.47 8.86 0.75
141 INT164756 Negative_regulation of PDGFRB 2 32 0.57 21.69 0.72
142 INT249114 Gene_expression of Cd48 1 2 0.10 5.06 0.68
143 INT336876 Negative_regulation of FRZB 1 2 0.08 3.21 0.66
144 INT40698 Positive_regulation of Aes 1 3 0.32 3.84 0.65
145 INT124373 Positive_regulation of Gene_expression of Wnt2 1 14 0.42 8.28 0.6
146 INT245721 Localization of FRZB 3 6 0.78 4.3 0.6
147 INT128498 Regulation of CCND1 1 17 0.39 12.51 0.58
148 INT132781 Phosphorylation of PIK3CG 2 8 0.52 4.83 0.53
149 INT36703 Negative_regulation of CEACAM3 2 2 0.43 4.11 0.53
150 INT164021 Gene_expression of WIF1 1 6 0.77 2.43 0.51
151 INT138676 Localization of ADAM17 1 4 0.73 4.91 0.5
152 INT223599 Regulation of MTOR 2 14 0.42 8.52 0.49
153 INT242004 Binding of Tcf7 1 4 0.36 2.66 0.49
154 INT130801 Localization of SFRP4 2 4 0.28 2.41 0.49
155 INT199553 Gene_expression of Bcr 3 25 0.76 13.83 0.48
156 INT47030 Negative_regulation of ARMC9 1 22 0.38 13.08 0.47
157 INT201524 Localization of Wnt2 3 14 0.62 9.24 0.46
158 INT136655 Binding of BLZF1 1 4 0.17 0.72 0.43
159 INT98456 Negative_regulation of Src 2 17 0.42 8.3 0.42
160 INT262768 Negative_regulation of CD163L1 1 1 0.02 1.63 0.4
161 INT117662 Gene_expression of ABL1 1 21 0.69 18.76 0.39
162 INT131773 Regulation of KDR 2 12 0.49 12.01 0.39
163 INT64977 Gene_expression of TFF3 1 9 0.75 3.54 0.39
164 INT302086 Gene_expression of WNT2 1 3 0.14 0.97 0.38
165 INT289105 Gene_expression of WNT3 1 4 0.20 2.02 0.37
166 INT182314 Transcription of Birc5 1 4 0.69 2.69 0.37
167 INT336874 Localization of WIF1 2 1 0.53 0.87 0.37
168 INT193674 Binding of Bcr 3 10 0.47 4.3 0.36
169 INT216379 Positive_regulation of Gene_expression of WNT1 1 5 0.30 3.1 0.34
170 INT242149 Negative_regulation of Transcription of Wnt2 1 2 0.35 1.8 0.33
171 INT129454 Negative_regulation of Adamts13 1 6 0.30 7.78 0.31
172 INT156411 Gene_expression of Pdgfra 1 8 0.75 5.5 0.3
173 INT256540 Regulation of Gene_expression of TSC1 1 4 0.07 4.74 0.3
174 INT297626 Gene_expression of RLN3 2 3 0.11 5.07 0.3
175 INT242154 Negative_regulation of Gene_expression of Wnt2 1 2 0.35 0.89 0.3
176 INT146524 Negative_regulation of AADAC 1 5 0.04 4.2 0.28
177 INT265661 Positive_regulation of Gene_expression of HIST2H4A 2 2 0.09 2.69 0.28
178 INT147781 Negative_regulation of Gene_expression of CD55 1 4 0.39 5.48 0.27
179 INT121834 Gene_expression of IAPP 1 24 0.66 20.96 0.26
180 INT156207 Negative_regulation of Phosphorylation of MTOR 2 5 0.58 2.33 0.25
181 INT112837 Regulation of GPX1 1 3 0.17 1.81 0.25
182 INT156410 Positive_regulation of Pdgfra 1 3 0.08 1.51 0.25
183 INT124944 Regulation of KIT 1 15 0.60 11.84 0.24
184 INT152667 Negative_regulation of Transcription of AR 1 3 0.42 0.72 0.24
185 INT257785 Positive_regulation of KIN 1 3 0.45 0.72 0.24
186 INT257786 Localization of NCOR1 1 1 0.68 0.36 0.24
187 INT119080 Negative_regulation of PTK2 1 15 0.56 8.88 0.23
188 INT251788 Gene_expression of ESYT1 1 8 0.06 7.29 0.23
189 INT257782 Localization of TAB2 1 1 0.36 0.36 0.23
190 INT241498 Regulation of Abl1 1 8 0.32 6.46 0.22
191 INT336864 Negative_regulation of Tcf7 1 1 0.41 0.44 0.22
192 INT156204 Phosphorylation of MTOR 2 15 0.82 3.99 0.21
193 INT192958 Negative_regulation of IGF1R 1 8 0.30 6.35 0.21
194 INT249115 Localization of Pde6b 2 6 0.68 1.09 0.21
195 INT257784 Positive_regulation of Phosphorylation of AR 1 2 0.45 0.96 0.21
196 INT257783 Phosphorylation of TAB2 1 1 0.37 0.38 0.21
197 INT239412 Binding of ABL1 2 8 0.28 5.39 0.18
198 INT159231 Positive_regulation of PDGFRA 1 3 0.47 2.39 0.18
199 INT18379 Transcription of Cp 1 2 0.11 1.23 0.18
200 INT251787 Positive_regulation of ESYT1 3 1 0.05 3.77 0.17
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