J:J Immune Based Ther Vaccines

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT149117 Binding of CD80 and CTLA4 31 1 0.52 12.7 7.73
2 INT186126 Binding of CD28 and CTLA4 9 1 0.52 4.13 3.12
3 INT175329 Binding of ICAM1 and ITGAL 14 1 0.18 10.06 2.81
4 INT186128 Binding of CD2 and CD58 8 6 0.10 7.59 2.76
5 INT238005 Binding of Cxcr3 and Cxcl10 2 2 0.38 3.73 1.42
6 INT238009 Binding of Cxcr3 and Cxcl9 3 1 0.40 4.01 1.37
7 INT237999 Binding of Cxcr3 and Cxcl11 2 1 0.45 3.49 1.11
8 INT186125 Negative_regulation of Binding of CD2 and CD58 3 2 0.12 3.04 1.06
9 INT252602 Binding of Cxcl10 and Ppig 1 1 0.08 1.55 0.96
10 INT237083 Binding of Cxcl10 and Cxcl9 2 1 0.39 3.19 0.87
11 INT237084 Binding of Cxcl9 and Cxcl11 2 1 0.34 3.19 0.87
12 INT252603 Ppig Positive_regulation of Gene_expression of Cx3cl1 1 1 0.10 1.8 0.69
13 INT186123 Binding of GIF and IL10 1 1 0.23 1.17 0.69
14 INT252605 Ppig Positive_regulation of Gene_expression of Cx3cr1 1 1 0.09 1.81 0.69
15 INT177979 Binding of STAT3 and FOXI2 1 2 0.00 1.83 0.61
16 INT252601 Binding of Cxcl10 and Cxcl11 1 1 0.34 1.68 0.6
17 INT177981 Binding of RUNX1 and SLC22A4 1 1 0.08 1.04 0.5
18 INT186127 CTLA4 Negative_regulation of CD28 1 1 0.19 0.74 0.32
19 INT252599 Negative_regulation of Cxcl10 Negative_regulation of Gene_expression of Cxcr3 1 1 0.45 0.49 0.29
20 INT252604 Negative_regulation of Cxcl10 Negative_regulation of Gene_expression of Hand1 1 1 0.24 0.5 0.29
21 INT177978 Binding of CSF1R and SNRNP70 1 2 0.02 1.49 0.28
22 INT177977 RUNX1 Regulation of CSF1R 1 1 0.14 1 0.27
23 INT177982 Binding of RUNX1 and SNRNP70 1 1 0.01 0.89 0.21
24 INT252606 IFNA1 Positive_regulation of Gene_expression of Cxcl10 1 1 0.02 0.56 0.18
25 INT252600 Ppig Regulation of Hand1 1 1 0.06 0.43 0.17
26 INT252598 Ppig Regulation of Gene_expression of Hand1 1 1 0.06 0.43 0.17
27 INT355829 Binding of SETBP1 and LIN9 1 1 0.00 0.06 0.17
28 INT177980 CSF1R Regulation of PXN 1 1 0.07 0.48 0.11
29 INT183768 Csf2 Regulation of CD4 1 1 0.37 0.52 0.08
30 INT355828 Binding of MFGE8 and SEA 1 1 0.01 0.07 0.07
31 INT355857 Binding of Span and SETBP1 1 1 0.00 0.17 0.04
32 INT206685 IMPA1 Positive_regulation of HBS1L 1 1 0.00 0.24 0.04
33 INT183767 Csf2 Negative_regulation of Transcription of CCR5 1 1 0.17 0.92 0.03
34 INT183769 Csf2 Negative_regulation of Transcription of CXCR4 1 1 0.48 0.92 0.03
35 INT183757 INCENP Negative_regulation of Transcription of CXCR4 1 1 0.01 0.93 0.03
36 INT183758 INCENP Negative_regulation of Transcription of CCR5 1 1 0.00 0.93 0.03
37 INT183765 Csf2 Regulation of Hivan1 1 2 0.00 1.2 0
38 INT183766 Binding of Csf2 and Hivan1 1 1 0.00 0.82 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 7 3152 0.78 2515.62 929.82
2 INT9238 Gene_expression of IL6 1 1575 0.78 1135.66 424.22
3 INT5235 Negative_regulation of TNF 1 924 0.59 772.91 331.98
4 INT5059 Positive_regulation of TNF 1 1050 0.70 896.51 322.81
5 INT6852 Localization of TNF 1 883 0.81 705.95 270.84
6 INT5972 Gene_expression of IL1B 1 948 0.78 510.91 263.97
7 INT6481 Binding of TNF 1 624 0.48 510.2 214.82
8 INT6482 Positive_regulation of Gene_expression of TNF 2 659 0.70 569.88 210
9 INT867 Gene_expression of IFNA1 3 930 0.78 594.85 168.03
10 INT120811 Gene_expression of Gopc 1 1174 0.59 428.49 150.55
11 INT5116 Gene_expression of IL2 2 670 0.78 291.13 146.69
12 INT1273 Gene_expression of Avp 3 356 0.78 90.56 138.7
13 INT9235 Negative_regulation of Gene_expression of TNF 1 346 0.59 252.98 118.61
14 INT5940 Negative_regulation of Avp 1 236 0.59 67.86 101.2
15 INT11381 Positive_regulation of IL1B 1 330 0.70 209.31 100.9
16 INT11587 Gene_expression of CSF2 1 645 0.78 544.38 93.89
17 INT60691 Gene_expression of Il12a 1 331 0.78 208.03 75.96
18 INT11380 Negative_regulation of IL1B 1 215 0.59 125.62 72.35
19 INT170332 Gene_expression of IFN1@ 3 477 0.75 275.21 69.65
20 INT20375 Gene_expression of Hand1 5 213 0.60 148.51 54.53
21 INT117223 Gene_expression of TLR4 1 348 0.78 206.18 54.42
22 INT6473 Positive_regulation of Gene_expression of IL1B 1 204 0.70 117.23 50.86
23 INT4216 Gene_expression of CD40LG 2 328 0.78 256.02 44.23
24 INT25383 Gene_expression of Csf2 8 222 0.76 152.93 43.32
25 INT170054 Negative_regulation of Gopc 1 280 0.38 117.89 42.4
26 INT4004 Gene_expression of IGHG3 4 321 0.71 221.03 42.33
27 INT13556 Gene_expression of CD4 6 367 0.78 230.82 41.74
28 INT88322 Gene_expression of CCR5 1 111 0.78 77.36 39.84
29 INT168410 Gene_expression of Cxcr3 12 81 0.75 84.03 37.01
30 INT63349 Gene_expression of PECAM1 2 199 0.75 166.03 36.76
31 INT72651 Gene_expression of TH1L 2 114 0.75 80.15 35.15
32 INT6105 Positive_regulation of IL2 1 133 0.69 82.76 34.67
33 INT104392 Gene_expression of Cxcl10 26 113 0.75 106.86 34.12
34 INT10763 Localization of IL2 1 157 0.80 81.11 33.21
35 INT9694 Positive_regulation of Csf2 1 102 0.68 70.09 33.07
36 INT9993 Positive_regulation of Gene_expression of IL2 1 131 0.69 46.27 30.04
37 INT169180 Binding of SNRNP70 2 204 0.47 119.1 29.3
38 INT19856 Gene_expression of CD8A 2 240 0.75 147.86 26.39
39 INT5328 Positive_regulation of CD4 9 191 0.69 133.43 21.31
40 INT1876 Positive_regulation of HLA-B 1 82 0.69 52.16 21.08
41 INT14701 Negative_regulation of IFNA1 1 118 0.54 84.19 20.08
42 INT104395 Gene_expression of Cxcl9 15 83 0.76 73.1 19.79
43 INT18311 Positive_regulation of CD8A 1 145 0.69 113.48 19.44
44 INT636 Binding of MRAP 1 54 0.48 40.36 18.77
45 INT94467 Positive_regulation of Hand1 1 71 0.58 59 16.96
46 INT170051 Positive_regulation of Gene_expression of Gopc 1 150 0.43 56.75 16.93
47 INT65659 Positive_regulation of STAT3 1 132 0.70 69.56 15.95
48 INT170754 Localization of IFN1@ 1 121 0.78 66.78 15.6
49 INT75540 Positive_regulation of TH1L 1 62 0.67 43.45 15.02
50 INT89293 Positive_regulation of Gene_expression of CCR5 1 29 0.70 22.14 15
51 INT10709 Negative_regulation of CD4 2 106 0.59 95.6 14.89
52 INT16321 Gene_expression of Cd3e 1 111 0.72 49.9 14.21
53 INT17035 Positive_regulation of TFPI 2 55 0.61 34.88 14.18
54 INT3796 Gene_expression of Ighm 3 130 0.77 69.61 13.78
55 INT4931 Localization of IFNG 1 53 0.78 33.25 13.65
56 INT171134 Gene_expression of CD28 1 67 0.65 32.55 13.61
57 INT99780 Positive_regulation of Cxcl10 6 43 0.69 39.67 13.27
58 INT1125 Positive_regulation of IGHG3 4 130 0.69 112.07 13.18
59 INT132178 Binding of CD80 1 41 0.47 15.55 12.98
60 INT122812 Gene_expression of SNRNP70 2 130 0.75 67 12.5
61 INT70050 Negative_regulation of IL10 1 56 0.58 37.45 12.39
62 INT36287 Binding of CD4 1 96 0.47 58.93 11.88
63 INT176607 Gene_expression of Cx3cl1 1 27 0.75 19.51 11.32
64 INT94465 Positive_regulation of Gene_expression of Hand1 1 43 0.38 29.76 10.88
65 INT58904 Localization of TH1L 1 40 0.68 27.11 10.52
66 INT54473 Binding of ABCB1 2 30 0.48 8.65 10.38
67 INT99784 Positive_regulation of Cxcr3 2 22 0.66 22.44 10.36
68 INT16404 Regulation of CD4 2 54 0.61 33.05 10.29
69 INT10019 Binding of CD8A 2 57 0.36 31.49 10.08
70 INT73504 Binding of CD28 1 35 0.45 15.99 10.04
71 INT637 Positive_regulation of MRAP 1 23 0.67 21.13 9.97
72 INT170333 Binding of IFN1@ 1 68 0.47 49.01 9.72
73 INT80549 Binding of ICAM1 2 53 0.47 42.76 9.72
74 INT73497 Regulation of IL10 1 33 0.45 22.6 9.19
75 INT25381 Localization of Csf2 4 62 0.76 47.48 9.03
76 INT104394 Positive_regulation of Gene_expression of Cxcl10 8 28 0.65 25.64 8.79
77 INT22383 Binding of IL2 2 59 0.48 39.06 8.56
78 INT621 Positive_regulation of SERPINH1 1 19 0.57 21.52 8.44
79 INT91370 Phosphorylation of STAT3 1 123 0.82 49.25 8.42
80 INT174422 Binding of Cxcr3 11 24 0.47 26.09 8.34
81 INT132278 Binding of CTLA4 1 32 0.39 18.69 8.17
82 INT168642 Gene_expression of Cx3cr1 1 15 0.77 21.73 8.1
83 INT104387 Positive_regulation of Cxcl9 4 24 0.67 22.26 7.87
84 INT75841 Binding of Trav6-3 1 66 0.47 29.14 7.63
85 INT103909 Gene_expression of NOD2 2 37 0.77 21.9 7.36
86 INT174432 Transcription of Cxcr3 6 8 0.68 15.73 7.32
87 INT67822 Binding of SERPINH1 2 17 0.36 19.05 7.24
88 INT8793 Gene_expression of H2 1 58 0.75 26.36 7.07
89 INT127037 Gene_expression of Ppig 8 26 0.65 16.08 6.84
90 INT99782 Negative_regulation of Cxcl10 16 21 0.55 18.4 6.5
91 INT3795 Positive_regulation of Ighm 1 46 0.68 22.43 6.47
92 INT83451 Positive_regulation of Gene_expression of CD40LG 1 26 0.60 22.81 6.25
93 INT46721 Regulation of Csf2 2 26 0.45 20.4 6.18
94 INT61417 Gene_expression of ITGAL 1 36 0.75 29.62 6.15
95 INT93684 Gene_expression of STAT3 1 66 0.78 34.42 5.94
96 INT77076 Positive_regulation of Ppig 9 16 0.49 13.54 5.91
97 INT25394 Negative_regulation of Gene_expression of Csf2 2 22 0.52 13.18 5.84
98 INT237051 Gene_expression of Cxcl11 10 24 0.64 25.74 5.77
99 INT152433 Binding of CSF1R 1 6 0.33 10.97 5.54
100 INT170056 Binding of Cxcl10 4 11 0.45 12.72 5.32
101 INT16405 Regulation of CD8A 2 38 0.45 19.04 5.31
102 INT71418 Binding of CES1 1 42 0.40 29.78 5.01
103 INT82354 Positive_regulation of PECAM1 1 25 0.34 22.93 4.69
104 INT87322 Binding of ITGAL 2 23 0.47 15.73 4.68
105 INT104389 Positive_regulation of Gene_expression of Cxcl9 3 15 0.49 17.42 4.59
106 INT64653 Binding of CD2 2 17 0.44 6.74 4.45
107 INT35028 Positive_regulation of IL2RG 1 14 0.47 10.05 4.36
108 INT177992 Positive_regulation of SNRNP70 1 28 0.49 16.14 4.28
109 INT138916 Transcription of Cxcl9 5 13 0.68 9.88 3.96
110 INT127039 Negative_regulation of Ppig 2 13 0.21 5.29 3.87
111 INT152254 Gene_expression of CSF1R 9 16 0.75 12.93 3.81
112 INT9256 Gene_expression of SELPLG 1 30 0.75 16.44 3.66
113 INT160409 Transcription of Cxcl10 5 9 0.65 7.95 3.53
114 INT176386 Positive_regulation of Gene_expression of TH1L 1 14 0.32 9.17 3.4
115 INT237054 Negative_regulation of Gene_expression of Cxcl10 4 11 0.56 10.26 3.4
116 INT52021 Regulation of IGHG3 1 34 0.39 22.43 3.3
117 INT99787 Regulation of Cxcl10 5 9 0.43 6.37 3.02
118 INT78467 Negative_regulation of IL12A 1 18 0.38 11.29 2.98
119 INT133374 Gene_expression of Pdha1 1 3 0.12 1.44 2.98
120 INT105783 Protein_catabolism of IL6 1 7 0.48 4.72 2.95
121 INT177993 Localization of CSF1R 1 4 0.73 7.49 2.94
122 INT178002 Positive_regulation of CSF1R 1 2 0.37 6.52 2.74
123 INT94463 Regulation of Gene_expression of Hand1 1 10 0.36 5.17 2.72
124 INT83642 Gene_expression of CD63 1 22 0.77 10.06 2.63
125 INT170053 Binding of Cxcl9 2 5 0.46 6.34 2.43
126 INT220165 Positive_regulation of Cxcl11 1 8 0.60 9.67 2.29
127 INT5007 Gene_expression of IGHM 2 8 0.09 1.48 2.19
128 INT138920 Regulation of Gene_expression of Cxcl10 2 5 0.59 5.72 2.1
129 INT177998 Binding of RUNX1 3 7 0.35 7.12 2.08
130 INT3797 Positive_regulation of Gene_expression of Ighm 1 16 0.47 9.4 2.01
131 INT186134 Binding of IGHA1 1 5 0.01 4.71 1.99
132 INT92056 Transcription of Il12b 1 8 0.69 4.75 1.95
133 INT117221 Positive_regulation of Gene_expression of NOD2 1 7 0.65 4.39 1.83
134 INT90026 Gene_expression of FOXI2 1 5 0.03 0.98 1.79
135 INT166819 Gene_expression of IMPA1 1 12 0.65 3.85 1.77
136 INT117546 Gene_expression of SETBP1 10 5 0.69 3.31 1.7
137 INT95134 Binding of TH1L 1 6 0.47 3.67 1.68
138 INT114734 Localization of ANTXR2 1 5 0.73 3.28 1.62
139 INT94827 Gene_expression of HBS1L 7 24 0.67 26.11 1.61
140 INT183761 Phosphorylation of Csf2 1 6 0.80 4.04 1.58
141 INT46722 Regulation of Gene_expression of Csf2 1 8 0.45 4.84 1.45
142 INT153218 Positive_regulation of Transcription of Cxcl9 1 4 0.45 3.57 1.42
143 INT174486 Regulation of Gene_expression of CD4 2 12 0.36 6.09 1.39
144 INT138913 Negative_regulation of Gene_expression of Cxcl9 2 8 0.58 6.22 1.36
145 INT138911 Negative_regulation of Cxcl9 2 5 0.42 3.31 1.35
146 INT117548 Positive_regulation of SETBP1 5 2 0.45 0.57 1.34
147 INT119669 Gene_expression of Igh-VS107 2 9 0.49 3.95 1.31
148 INT206696 Regulation of Gene_expression of TH1L 1 5 0.20 4.44 1.26
149 INT252588 Transcription of Cxcl11 4 1 0.60 3.61 1.24
150 INT99325 Positive_regulation of Pdha1 1 6 0.49 1.55 1.22
151 INT91368 Negative_regulation of Phosphorylation of STAT3 1 14 0.59 9.22 1.2
152 INT237047 Positive_regulation of Gene_expression of Cxcl11 1 5 0.43 5.04 1.17
153 INT9257 Positive_regulation of SELPLG 1 5 0.45 3.57 1.16
154 INT252582 Positive_regulation of Gene_expression of Ppig 2 3 0.12 2.62 1.13
155 INT174447 Regulation of Cxcr3 2 1 0.60 2.68 1.12
156 INT1938 Positive_regulation of DONSON 1 3 0.13 3.02 1.07
157 INT22830 Negative_regulation of Binding of IL2 1 4 0.55 4.8 1.06
158 INT131161 Binding of CD58 2 5 0.17 3.54 1.03
159 INT155156 Gene_expression of TCN1 1 13 0.58 3.25 0.99
160 INT182211 Transcription of CXCR4 1 5 0.69 3.8 0.95
161 INT206699 Positive_regulation of Binding of IFN1@ 1 6 0.49 3.75 0.88
162 INT177997 Regulation of SLC22A4 1 2 0.20 3.88 0.86
163 INT99781 Positive_regulation of Negative_regulation of Cxcl10 1 2 0.50 0.97 0.8
164 INT178004 Binding of SLC22A4 1 2 0.26 2.45 0.77
165 INT51656 Positive_regulation of Hivan1 1 5 0.06 7.66 0.76
166 INT15783 Regulation of SMS 1 6 0.23 3.2 0.75
167 INT186135 Negative_regulation of Binding of ITGAL 1 5 0.34 3.27 0.74
168 INT185049 Transcription of Hand1 1 5 0.47 1.84 0.71
169 INT211272 Positive_regulation of Igh-VS107 1 8 0.37 5.79 0.7
170 INT40084 Binding of HBS1L 2 8 0.36 9.15 0.69
171 INT246406 Binding of SETBP1 10 5 0.43 3.79 0.69
172 INT186136 Negative_regulation of Binding of CD2 1 2 0.29 2.06 0.68
173 INT196866 Localization of Ppig 1 2 0.17 0.58 0.64
174 INT94826 Positive_regulation of HBS1L 3 13 0.40 4.62 0.61
175 INT252587 Binding of Cxcl11 1 1 0.30 1.62 0.6
176 INT103782 Binding of Ppig 3 5 0.12 2.57 0.58
177 INT237990 Regulation of Gene_expression of Cxcl9 1 2 0.44 1.91 0.58
178 INT131160 Negative_regulation of Binding of CD58 1 2 0.15 1.83 0.53
179 INT90679 Negative_regulation of Hivan1 1 18 0.07 11.62 0.51
180 INT177990 Regulation of RUNX1 1 1 0.13 1.07 0.51
181 INT126119 Positive_regulation of TCN1 1 9 0.43 1.31 0.48
182 INT246407 Localization of SETBP1 8 2 0.72 0.82 0.48
183 INT178000 Positive_regulation of Gene_expression of CSF1R 1 1 0.46 0.85 0.46
184 INT98138 Localization of FURIN 1 3 0.72 1.84 0.43
185 INT183759 Negative_regulation of Localization of Csf2 2 3 0.42 1.28 0.42
186 INT252586 Regulation of Transcription of Cxcl10 1 1 0.43 0.81 0.42
187 INT252585 Regulation of Cxcl11 1 1 0.51 0.95 0.41
188 INT252596 Positive_regulation of Binding of Cxcr3 1 1 0.49 1.19 0.41
189 INT177754 Binding of FURIN 1 2 0.31 1.12 0.36
190 INT252590 Regulation of Transcription of Hand1 1 1 0.36 0.76 0.36
191 INT178001 Regulation of Negative_regulation of FOXI2 1 1 0.00 1.01 0.34
192 INT177996 Negative_regulation of FOXI2 1 1 0.01 1.01 0.34
193 INT252595 Regulation of Negative_regulation of Ppig 1 1 0.12 0.78 0.34
194 INT252581 Positive_regulation of Positive_regulation of Ppig 2 1 0.11 1.26 0.34
195 INT177994 Negative_regulation of Phosphorylation of CSF1R 1 1 0.39 1 0.34
196 INT252589 Regulation of Negative_regulation of Cxcl10 1 1 0.43 0.77 0.34
197 INT355843 Positive_regulation of Gene_expression of SETBP1 4 1 0.45 1.01 0.33
198 INT177999 Phosphorylation of CSF1R 1 1 0.75 0.99 0.33
199 INT239861 Gene_expression of Itga2 1 5 0.65 1.32 0.32
200 INT177995 Phosphorylation of FOXI2 1 1 0.01 0.93 0.31
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