J:J Neuroimmune Pharmacol

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 1 4 0.15 0.68 3.17
2 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 3 0.19 0.52 2.46
3 INT149491 PNOC Negative_regulation of Gene_expression of CD14 1 2 0.40 0.37 1.76
4 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 2 0.45 0.76 1.03
5 INT149493 PNOC Negative_regulation of CCL5 1 1 0.14 0.16 0.77
6 INT149495 PNOC Negative_regulation of CCL2 1 1 0.11 0.16 0.77
7 INT149480 CEBPD Positive_regulation of CEBPB 1 1 0.50 0.15 0.58
8 INT149479 CEBPD Positive_regulation of C3 1 1 0.30 0.14 0.57
9 INT156246 NFKB1 Regulation of Gene_expression of TNF 1 1 0.17 0.35 0.54
10 INT325056 Binding of E2f1 and Ang 1 1 0.06 1.3 0.12
11 INT325057 Binding of Hand1 and Ang 1 1 0.01 1.29 0.12
12 INT325059 Insr Positive_regulation of Ang 1 1 0.02 1.4 0.08
13 INT325058 Igf1 Positive_regulation of Ang 1 1 0.04 1.4 0.08
14 INT325060 Binding of Insr and Hand1 1 1 0.00 0.16 0.05

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3 3152 0.78 2515.62 929.82
2 INT5895 Gene_expression of Oprm1 4 525 0.78 120.67 407.29
3 INT5059 Positive_regulation of TNF 1 1050 0.70 896.51 322.81
4 INT9158 Gene_expression of Tnf 4 722 0.78 522.01 277.68
5 INT6852 Localization of TNF 9 883 0.81 705.95 270.84
6 INT16868 Gene_expression of Il6 3 807 0.78 499.48 256.57
7 INT95787 Positive_regulation of Mapk1 1 568 0.70 226.51 220.94
8 INT22548 Positive_regulation of Casp3 1 483 0.70 258.78 213.07
9 INT6482 Positive_regulation of Gene_expression of TNF 1 659 0.70 569.88 210
10 INT11313 Positive_regulation of Il6 2 526 0.70 331.27 201.59
11 INT94952 Positive_regulation of Mapk14 2 305 0.70 197.83 186.61
12 INT55879 Gene_expression of CCL2 4 421 0.78 240.74 166.02
13 INT49134 Gene_expression of Grin1 3 270 0.78 84.78 148.61
14 INT13353 Positive_regulation of Tnf 3 332 0.70 248.75 148.1
15 INT9660 Regulation of TNF 1 363 0.62 312.94 139.99
16 INT7341 Positive_regulation of Grin1 6 169 0.70 65.86 118.38
17 INT10272 Gene_expression of Il1b 3 194 0.78 121.02 103.03
18 INT82878 Gene_expression of Ccl2 1 201 0.78 164.95 101.35
19 INT11381 Positive_regulation of IL1B 3 330 0.70 209.31 100.9
20 INT96917 Positive_regulation of Mapk14 1 261 0.70 173.29 88.79
21 INT54571 Positive_regulation of NFKB1 1 263 0.70 138.99 87.32
22 INT5610 Positive_regulation of Insr 1 140 0.69 37.26 86.24
23 INT60691 Gene_expression of Il12a 1 331 0.78 208.03 75.96
24 INT10274 Positive_regulation of Il1b 3 123 0.70 79.76 73.56
25 INT9236 Regulation of Gene_expression of TNF 1 204 0.62 162.66 72.99
26 INT11380 Negative_regulation of IL1B 1 215 0.59 125.62 72.35
27 INT49995 Positive_regulation of Gene_expression of Tnf 2 187 0.70 125.07 70.54
28 INT7534 Gene_expression of Ifng 1 193 0.78 111.02 68.6
29 INT11318 Gene_expression of Gtf3a 2 274 0.52 183.82 60.89
30 INT8732 Positive_regulation of Gene_expression of Oprm1 1 76 0.70 22.59 58.83
31 INT7340 Regulation of Grin1 1 87 0.62 30.37 57.93
32 INT78899 Gene_expression of CCL5 3 155 0.77 84.02 55.09
33 INT63975 Positive_regulation of Il10 1 175 0.68 134.13 54.69
34 INT22112 Positive_regulation of Localization of TNF 1 164 0.70 115.66 52.18
35 INT17915 Gene_expression of Insr 2 141 0.75 47.45 48.59
36 INT57021 Positive_regulation of Gene_expression of Grin1 3 62 0.70 24.77 47.31
37 INT52531 Gene_expression of Nfkb1 1 153 0.75 82.84 42.9
38 INT11439 Positive_regulation of Csf2 1 105 0.69 62.63 37.77
39 INT84260 Positive_regulation of Mapk8 2 124 0.69 72.84 35.98
40 INT52350 Gene_expression of CD14 2 184 0.75 71.37 33.13
41 INT8915 Gene_expression of Igf1 2 199 0.78 78.58 32.51
42 INT22939 Gene_expression of Csf2 1 164 0.78 85.1 32.22
43 INT5300 Regulation of Insr 2 54 0.60 11.33 29.26
44 INT21900 Gene_expression of Mthfd1 1 150 0.75 69.47 27.03
45 INT53482 Gene_expression of ITIH4 1 75 0.77 58.87 26.05
46 INT95788 Positive_regulation of Positive_regulation of Mapk1 1 83 0.69 24.75 25.84
47 INT106272 Positive_regulation of Positive_regulation of Mapk14 1 39 0.70 32.08 24.71
48 INT48536 Positive_regulation of Grm8 4 46 0.61 14.31 23.56
49 INT12475 Gene_expression of OPRL1 2 35 0.77 3.63 23.11
50 INT55170 Gene_expression of NFKB1 1 97 0.77 52.75 23.04
51 INT52529 Regulation of Nfkb1 2 48 0.61 26.2 20.89
52 INT60690 Positive_regulation of Gene_expression of Il12a 1 69 0.63 41.41 20.85
53 INT48144 Gene_expression of Fgf2 1 117 0.78 43 20.48
54 INT756 Gene_expression of C3 2 138 0.75 100.6 19.2
55 INT66755 Transcription of Tnf 1 45 0.72 37.1 19.11
56 INT73252 Positive_regulation of Mthfd1 3 124 0.59 59.48 18.35
57 INT35086 Positive_regulation of Gene_expression of Ifng 1 40 0.69 22.55 18.35
58 INT16624 Localization of Grin1 3 38 0.79 8.46 17.15
59 INT103757 Negative_regulation of Il12a 1 37 0.55 21.62 16.38
60 INT50932 Positive_regulation of Positive_regulation of Il6 2 36 0.69 24.9 16.12
61 INT61548 Positive_regulation of Fgf2 1 72 0.70 32.18 14.49
62 INT64048 Positive_regulation of Positive_regulation of Tnf 2 32 0.70 21.24 13.74
63 INT69878 Positive_regulation of Gene_expression of Gtf3a 2 48 0.29 36.78 13.57
64 INT104954 Negative_regulation of Positive_regulation of Mapk14 2 29 0.58 17.71 13.31
65 INT17539 Positive_regulation of Igf1 1 68 0.69 28.47 13.02
66 INT110025 Positive_regulation of Positive_regulation of Mapk14 1 39 0.63 20.67 12.71
67 INT4137 Positive_regulation of C3 4 73 0.69 48.57 12.63
68 INT1218 Negative_regulation of Maob 1 24 0.59 9.76 9.39
69 INT111998 Positive_regulation of Positive_regulation of Mapk8 2 23 0.69 9.33 8.97
70 INT99163 Positive_regulation of Cd14 1 18 0.49 16.02 7.91
71 INT80822 Positive_regulation of MRGPRX1 1 30 0.67 3.66 7.73
72 INT50195 Positive_regulation of Positive_regulation of Il1b 2 12 0.67 7.41 7.64
73 INT65206 Regulation of PNOC 1 8 0.38 1.61 7.43
74 INT11378 Negative_regulation of Positive_regulation of IL1B 2 23 0.59 10.28 7.26
75 INT66752 Positive_regulation of Transcription of Tnf 1 15 0.68 10.86 7.26
76 INT81493 Transcription of CCL2 1 20 0.65 13.63 6.78
77 INT8916 Regulation of Igf1 1 45 0.60 13.06 5.81
78 INT92280 Transcription of OPRL1 1 10 0.70 1.36 5.68
79 INT111404 Regulation of Positive_regulation of Grin1 1 5 0.56 2.49 4.31
80 INT51084 Binding of Insr 2 13 0.30 4.25 4.23
81 INT54701 Localization of Ptafr 4 19 0.49 18.68 3.82
82 INT4012 Negative_regulation of Psd 1 23 0.52 14.12 3.81
83 INT103281 Transcription of CCL5 1 10 0.67 5.95 3.7
84 INT61547 Regulation of Fgf2 1 21 0.47 7.23 3.24
85 INT163529 Negative_regulation of Positive_regulation of Mapk8 2 14 0.43 8.37 3.2
86 INT62012 Gene_expression of Trafd1 1 11 0.31 8.53 3.13
87 INT185482 Binding of Cxcl10 1 5 0.30 3.76 3.13
88 INT153346 Binding of Cd14 2 11 0.31 8.64 3.06
89 INT131897 Phosphorylation of Kcna6 1 7 0.70 4.75 2.8
90 INT120483 Localization of ITIH4 4 11 0.69 12.05 2.51
91 INT157816 Positive_regulation of Positive_regulation of Mthfd1 1 5 0.33 3.73 1.93
92 INT169862 Regulation of NPC1 1 13 0.53 13.61 1.84
93 INT87454 Gene_expression of Hbegf 1 11 0.66 2.1 1.67
94 INT99097 Positive_regulation of GLB1 1 7 0.49 3.45 1.52
95 INT56226 Positive_regulation of RT1-EC2 3 1 0.25 3.6 1.48
96 INT107075 Gene_expression of Cd69 2 10 0.62 5.33 1.41
97 INT73365 Positive_regulation of Ang 1 10 0.67 3.8 1.36
98 INT146915 Transcription of CD14 1 7 0.67 3.7 1.36
99 INT157817 Negative_regulation of Il23a 1 6 0.39 3.34 1.33
100 INT281236 Positive_regulation of Tas2r134 3 2 0.06 3.36 1.08
101 INT90785 Negative_regulation of Ang 7 3 0.42 8.34 1.06
102 INT325047 Gene_expression of Hand1 7 1 0.07 6.42 1.06
103 INT161766 Localization of Psd 1 7 0.75 3.53 0.96
104 INT87453 Regulation of Hbegf 1 3 0.20 1.05 0.94
105 INT76551 Regulation of Ang 1 7 0.45 2.6 0.9
106 INT79956 Positive_regulation of Positive_regulation of C3 1 4 0.35 4.17 0.86
107 INT28689 Negative_regulation of Positive_regulation of C3 1 4 0.23 1.28 0.85
108 INT96480 Negative_regulation of Positive_regulation of Mthfd1 1 5 0.30 0.99 0.83
109 INT149485 Regulation of Gene_expression of C3 1 5 0.60 3.39 0.75
110 INT149496 Regulation of Positive_regulation of MRGPRX1 1 1 0.24 0.18 0.61
111 INT325055 Binding of Hand1 4 1 0.04 2.15 0.58
112 INT148107 Binding of CDIPT 2 8 0.17 4.56 0.53
113 INT205200 Positive_regulation of Pik3c3 1 7 0.08 2.76 0.51
114 INT275395 Regulation of Gene_expression of ITIH4 1 4 0.26 2.26 0.5
115 INT163035 Gene_expression of E2f1 1 8 0.71 2.68 0.47
116 INT149497 Gene_expression of OGFRL1 1 1 0.45 0.13 0.45
117 INT12003 Gene_expression of Ang 2 4 0.64 3.87 0.44
118 INT12004 Localization of Ang 1 3 0.39 1.3 0.31
119 INT325048 Positive_regulation of Gene_expression of Hand1 1 1 0.05 1.16 0.28
120 INT274071 Positive_regulation of Map3k5 1 3 0.38 2.31 0.22
121 INT71718 Positive_regulation of Hbegf 1 4 0.59 0.63 0.16
122 INT325053 Regulation of E2f1 2 1 0.19 2.02 0.15
123 INT325044 Binding of Ang 1 1 0.12 0.47 0.12
124 INT325045 Negative_regulation of Hand1 1 1 0.04 1.26 0.12
125 INT325052 Regulation of Negative_regulation of Ang 1 1 0.10 1.08 0.11
126 INT325046 Negative_regulation of Positive_regulation of Map3k5 1 1 0.07 0.64 0.11
127 INT325054 Positive_regulation of Gene_expression of Trafd1 1 1 0.01 0.8 0.04
128 INT325051 Regulation of Hand1 2 1 0.04 1.87 0.04
129 INT325049 Regulation of Gene_expression of Trafd1 1 1 0.01 0.8 0.04
130 INT148109 Gene_expression of Yod1 1 1 0.22 1.64 0.04
131 INT325061 Regulation of Regulation of NPC1 1 1 0.01 0.76 0.03
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