J:J Ocul Biol Dis Infor

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT24388 CRH Positive_regulation of Localization of POMC 8 2 0.51 5.67 3.35
2 INT134212 CRH Regulation of Localization of POMC 1 1 0.47 2.89 2.9
3 INT222811 Binding of Hand2 and TH1L 4 2 0.03 8.26 0.69
4 INT278423 Binding of Emp1 and Map2 1 1 0.06 0.46 0.12
5 INT278441 Lbp Positive_regulation of Gene_expression of ITGAX 1 1 0.44 1.18 0.07
6 INT278438 Lbp Positive_regulation of Il2 1 2 0.12 0.89 0
7 INT291896 Pkd2l1 Regulation of Gene_expression of Rtcd1 1 1 0.04 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 1 3152 0.78 2515.62 929.82
2 INT443 Localization of POMC 3 1020 0.81 284.52 443.17
3 INT6852 Localization of TNF 1 883 0.81 705.95 270.84
4 INT68684 Gene_expression of VEGFA 1 2371 0.78 1742.52 259.2
5 INT6481 Binding of TNF 2 624 0.48 510.2 214.82
6 INT120811 Gene_expression of Gopc 2 1174 0.59 428.49 150.55
7 INT64161 Positive_regulation of Prkca 1 213 0.70 85.06 129.91
8 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1 1138 0.72 311.58 119.18
9 INT1026 Binding of Lbp 1 207 0.48 150.96 119.16
10 INT170025 Gene_expression of Fig4 3 588 0.67 183.27 113.32
11 INT12082 Localization of IL6 3 365 0.81 241.78 105.78
12 INT56298 Gene_expression of IL4 1 306 0.78 182.18 72.92
13 INT79494 Positive_regulation of Gene_expression of VEGFA 1 577 0.70 442.94 69.73
14 INT1951 Positive_regulation of Tlr4 1 345 0.70 176.99 62.42
15 INT11318 Gene_expression of Gtf3a 1 274 0.52 183.82 60.89
16 INT5453 Regulation of Localization of POMC 1 114 0.62 20.56 56.34
17 INT64159 Gene_expression of Prkca 4 90 0.78 34.65 55.97
18 INT1027 Gene_expression of Lbp 4 132 0.77 106.7 54.16
19 INT22112 Positive_regulation of Localization of TNF 1 164 0.70 115.66 52.18
20 INT12345 Gene_expression of Il2 1 142 0.78 59.17 51.21
21 INT20382 Gene_expression of Hand2 1 211 0.66 142.26 51.05
22 INT1028 Positive_regulation of Lbp 3 102 0.69 67.86 46.05
23 INT80124 Negative_regulation of VEGFA 1 450 0.58 311.19 44.53
24 INT9372 Negative_regulation of Lbp 1 86 0.58 46.54 41.71
25 INT5454 Localization of CRH 2 124 0.79 79.18 41.53
26 INT69437 Positive_regulation of ROS1 2 328 0.58 222.83 40.56
27 INT3758 Gene_expression of ALB 2 326 0.78 184.65 38.75
28 INT72651 Gene_expression of TH1L 2 114 0.75 80.15 35.15
29 INT77310 Gene_expression of Aif1 2 89 0.78 50.49 33.68
30 INT7082 Gene_expression of CRH 2 180 0.78 64.66 31.74
31 INT65960 Gene_expression of BCL2 1 352 0.78 312.03 30.73
32 INT66200 Gene_expression of Gfap 3 215 0.78 88.04 28.25
33 INT3760 Positive_regulation of ALB 3 142 0.70 87.46 26.7
34 INT1030 Localization of Lbp 4 52 0.74 38.92 24.91
35 INT172458 Regulation of Gopc 1 155 0.53 62.57 24.86
36 INT74423 Localization of IL10 3 91 0.80 61.6 22.95
37 INT40750 Gene_expression of Mif 3 61 0.78 34.59 20.28
38 INT111401 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 134 0.61 34.87 20.15
39 INT3952 Negative_regulation of ALB 1 116 0.59 72.18 18.35
40 INT52179 Regulation of Lbp 2 39 0.61 25.4 18.32
41 INT116736 Positive_regulation of Mif 1 40 0.70 31.93 15.37
42 INT173505 Localization of Hand2 3 63 0.57 45.32 13.66
43 INT1491 Regulation of Rtcd1 1 33 0.53 5.17 13.4
44 INT76469 Positive_regulation of Gene_expression of Prkca 1 18 0.46 7.9 13.36
45 INT69158 Localization of IL4 3 48 0.71 31.3 11.98
46 INT57187 Positive_regulation of Gfap 2 49 0.69 27.59 11.46
47 INT94784 Binding of ROS1 1 113 0.40 71.57 10.26
48 INT24328 Gene_expression of Egf 1 97 0.75 59.65 9.42
49 INT32692 Positive_regulation of Aif1 3 33 0.35 13.29 9.03
50 INT22383 Binding of IL2 1 59 0.48 39.06 8.56
51 INT61628 Negative_regulation of Gene_expression of IL4 1 31 0.55 20.96 8.18
52 INT74290 Gene_expression of C3ar1 1 20 0.39 16.33 7.16
53 INT3757 Positive_regulation of Gene_expression of ALB 1 45 0.69 23.73 6.85
54 INT132822 Localization of IL13 3 26 0.67 22.85 6.66
55 INT91721 Binding of IL18 1 21 0.48 21.17 6.56
56 INT64052 Positive_regulation of FGFR1 5 26 0.52 28.47 6.36
57 INT132573 Negative_regulation of Gene_expression of TH1L 1 16 0.42 11.52 5.76
58 INT57502 Positive_regulation of Gene_expression of CRH 1 30 0.70 23.37 5.7
59 INT89959 Positive_regulation of Gene_expression of Aif1 1 14 0.58 7.44 5.05
60 INT12726 Gene_expression of Rtcd1 5 17 0.32 2.55 4.76
61 INT94466 Regulation of Gene_expression of Hand2 1 14 0.28 7.97 4.46
62 INT69217 Gene_expression of Notch1 1 20 0.78 7.8 4.41
63 INT57338 Gene_expression of ITGAX 1 31 0.75 24.62 4.39
64 INT39060 Gene_expression of Mpz 2 45 0.77 21.55 4.3
65 INT30014 Positive_regulation of HPSE 2 22 0.70 20.91 4.09
66 INT115890 Gene_expression of Nefh 1 28 0.68 11.55 3.84
67 INT35175 Localization of IL18 3 18 0.80 12.96 3.83
68 INT116738 Positive_regulation of Gene_expression of Mif 3 14 0.68 10.99 3.8
69 INT15002 Regulation of Gfap 1 17 0.37 5.34 3.61
70 INT133733 Positive_regulation of Localization of Lbp 3 6 0.43 9.19 3.61
71 INT69155 Positive_regulation of Localization of IL4 3 13 0.40 10.18 3.56
72 INT79553 Localization of Il12a 1 9 0.31 5.85 3.16
73 INT96338 Gene_expression of HPSE 1 17 0.75 18.71 2.73
74 INT163405 Positive_regulation of Binding of ROS1 1 15 0.27 9.39 2.58
75 INT142908 Localization of FGFR1 1 18 0.38 11.46 2.57
76 INT131112 Phosphorylation of Casp3 1 7 0.63 4.1 2.46
77 INT174876 Regulation of Gene_expression of Fig4 1 18 0.39 7.83 2.44
78 INT206514 Transcription of Tg(CAG-EGFP)D4Nagy 1 19 0.59 3.25 2.32
79 INT172808 Positive_regulation of Positive_regulation of ROS1 1 35 0.40 31.39 2.27
80 INT288630 Gene_expression of Cntf 2 6 0.75 3.99 1.89
81 INT44149 Regulation of Gene_expression of Mif 1 6 0.54 2.45 1.63
82 INT196967 Gene_expression of mea 1 9 0.27 1.47 1.55
83 INT60162 Gene_expression of Ie 1 41 0.58 23.77 1.52
84 INT77311 Localization of Aif1 2 10 0.75 4.21 1.5
85 INT112109 Gene_expression of FIGF 1 13 0.31 8.31 1.44
86 INT5399 Positive_regulation of Lepre1 1 5 0.31 4.42 1.39
87 INT151386 Negative_regulation of Emp1 1 3 0.31 2.99 1.38
88 INT206696 Regulation of Gene_expression of TH1L 1 5 0.20 4.44 1.26
89 INT146200 Positive_regulation of Rho 1 20 0.45 2.1 1.23
90 INT160235 Positive_regulation of Gene_expression of FIGF 1 4 0.20 5.53 1
91 INT26295 Positive_regulation of mea 1 4 0.49 1.08 0.91
92 INT97374 Gene_expression of Egln3 6 2 0.75 10.27 0.75
93 INT190780 Regulation of Gene_expression of Rtcd1 1 2 0.19 0.93 0.68
94 INT264709 Gene_expression of Hes1 1 24 0.76 7.04 0.63
95 INT185244 Gene_expression of Sox2 1 27 0.65 4.71 0.61
96 INT123651 Negative_regulation of Ufm1 1 2 0.04 1.69 0.57
97 INT145146 Gene_expression of Lepre1 1 2 0.19 1.76 0.47
98 INT211264 Gene_expression of Hk2 3 7 0.56 12.12 0.46
99 INT278425 Binding of Tnfrsf4 1 2 0.03 1.3 0.44
100 INT261870 Gene_expression of Pkd2l1 7 10 0.54 1.5 0.42
101 INT88453 Gene_expression of Uncx 2 5 0.33 2.48 0.42
102 INT125954 Regulation of Emp1 2 3 0.43 2.66 0.41
103 INT278422 Protein_catabolism of Emp1 1 1 0.64 2.45 0.38
104 INT112110 Positive_regulation of FIGF 1 3 0.18 5.28 0.37
105 INT278419 Localization of Map2 1 3 0.58 1.21 0.36
106 INT158258 Regulation of Tnfrsf4 1 3 0.04 0.67 0.35
107 INT285014 Gene_expression of Bnip3 5 4 0.61 10.38 0.29
108 INT201143 Regulation of Sox2 1 6 0.44 2.71 0.26
109 INT278418 Binding of Emp1 1 1 0.27 0.47 0.26
110 INT12723 Positive_regulation of Gene_expression of Rtcd1 1 2 0.21 0 0.18
111 INT291874 Gene_expression of Snw1 8 1 0.11 0.14 0.18
112 INT165802 Phosphorylation of Eif2ak2 1 2 0.80 2.71 0.17
113 INT185254 Gene_expression of Pax6 1 14 0.72 1.77 0.16
114 INT158260 Gene_expression of Tnfrsf4 1 7 0.23 1.51 0.15
115 INT224640 Positive_regulation of Mier1 1 2 0.67 3.73 0.14
116 INT85204 Protein_catabolism of Rtcd1 1 2 0.24 0.22 0.12
117 INT201144 Regulation of Gene_expression of Sox2 1 3 0.44 0.82 0.11
118 INT291897 Positive_regulation of Gene_expression of mea 1 2 0.20 0.61 0.11
119 INT291881 Regulation of Pkd2l1 1 1 0.14 0 0.08
120 INT291876 Transcription of Rtcd1 1 1 0.22 0 0.08
121 INT17980 Positive_regulation of Egln3 2 2 0.58 2.52 0.07
122 INT271542 Localization of Pkd2l1 1 2 0.23 0.1 0.07
123 INT278421 Transcription of Emp1 1 1 0.50 0.41 0.05
124 INT291879 Gene_expression of Rcvrn 5 6 0.47 0.64 0.04
125 INT260465 Positive_regulation of Hk2 1 2 0.44 2.95 0.04
126 INT264717 Negative_regulation of Hes1 1 7 0.42 0.77 0.03
127 INT264704 Regulation of Hes1 2 4 0.44 1.03 0.03
128 INT201142 Negative_regulation of Sox2 1 4 0.57 0.59 0
129 INT176161 Binding of TCHP 1 2 0.06 1.45 0
130 INT264719 Regulation of Gene_expression of Hes1 1 2 0.28 0.12 0
131 INT285039 Positive_regulation of Positive_regulation of Rho 1 2 0.26 0.06 0
132 INT291889 Negative_regulation of Pax6 1 2 0.45 0.39 0
133 INT291878 Positive_regulation of Positive_regulation of Rcvrn 1 1 0.37 0 0
134 INT291882 Protein_catabolism of Pkd2l1 2 1 0.32 0.4 0
135 INT296007 Gene_expression of Phf2 1 1 0.01 1.36 0
136 INT296004 Positive_regulation of Gene_expression of Egln3 2 1 0.67 3.36 0
137 INT291873 Regulation of Tuba3b 1 1 0.01 0 0
138 INT296000 Regulation of Gene_expression of Oxr1 1 1 0.38 2.51 0
139 INT296006 Regulation of Oxr1 1 1 0.38 2.66 0
140 INT291877 Regulation of Snw1 1 1 0.06 0 0
141 INT255236 Regulation of MCDR1 1 1 0.10 0.06 0
142 INT291888 Regulation of Gene_expression of Pax6 1 1 0.33 0 0
143 INT291886 Positive_regulation of Cdhr1 1 1 0.02 0 0
144 INT291883 Positive_regulation of Rcvrn 1 1 0.37 0 0
145 INT296005 Positive_regulation of Oxr1 1 1 0.43 2.79 0
146 INT295999 Negative_regulation of Gene_expression of Uncx 1 1 0.25 1.08 0
147 INT291887 Positive_regulation of Gene_expression of Rcvrn 2 1 0.37 0 0
148 INT296002 Negative_regulation of Egln3 3 1 0.56 4.48 0
149 INT291880 Positive_regulation of Snw1 1 1 0.07 0.07 0
150 INT255235 Regulation of Gene_expression of MCDR1 1 1 0.07 0.57 0
151 INT291884 Negative_regulation of Tuba3b 1 1 0.01 0 0
152 INT296003 Gene_expression of Oxr1 1 1 0.48 2.5 0
153 INT291890 Positive_regulation of Protein_catabolism of Pkd2l1 1 1 0.16 0.25 0
154 INT255234 Gene_expression of MCDR1 3 1 0.11 1.39 0
155 INT291885 Regulation of Pax6 2 1 0.15 0 0
156 INT255237 Positive_regulation of Gene_expression of MCDR1 1 1 0.08 0.4 0
157 INT295998 Positive_regulation of Positive_regulation of Lepre1 2 1 0.09 2.46 0
158 INT255233 Negative_regulation of MCDR1 2 1 0.07 2.07 0
159 INT296001 Positive_regulation of Gene_expression of Bnip3 2 1 0.55 2.47 0
160 INT278429 Positive_regulation of Localization of Aif1 1 1 0.13 0.47 0
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