J:J Pain

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT145098 NGF Positive_regulation of BDNF 1 1 0.66 1.33 1.67
2 INT140532 Gtf3a Positive_regulation of DYT10 1 1 0.12 1.83 1.34
3 INT140531 Ngf Positive_regulation of DYT10 1 1 0.72 1.83 1.34
4 INT128310 Oprm1 Positive_regulation of Oprm1 1 1 0.00 0.1 1.29
5 INT114635 Hmox2 Positive_regulation of Gene_expression of Fos 1 1 0.47 0.88 1.26
6 INT125696 Binding of OPRM1 and SNRNP70 1 1 0.06 0.99 1.15
7 INT125699 CR1 Negative_regulation of Positive_regulation of ABCA1 1 1 0.03 0.64 0.53
8 INT114647 Fos Positive_regulation of Gene_expression of PDYN 1 1 0.48 0.52 0.52

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 15 3083 0.78 894.43 1639.02
2 INT1912 Gene_expression of Calca 3 1152 0.78 453.25 739.84
3 INT5202 Positive_regulation of Gene_expression of Fos 6 1163 0.70 319.28 684
4 INT2543 Positive_regulation of Calca 2 787 0.70 331.13 592.08
5 INT6056 Negative_regulation of Gene_expression of Fos 9 601 0.59 193.05 386.84
6 INT2540 Negative_regulation of Calca 1 538 0.59 172.11 384.38
7 INT720 Positive_regulation of POMC 1 807 0.70 237.37 353.83
8 INT5235 Negative_regulation of TNF 1 924 0.59 772.91 331.98
9 INT34869 Negative_regulation of PTGS2 3 778 0.59 366.76 319.85
10 INT5540 Positive_regulation of Oprm1 2 344 0.70 76.77 319.71
11 INT5680 Gene_expression of Ngf 7 530 0.78 264.29 310.56
12 INT4941 Positive_regulation of Oprd1 2 345 0.70 74.26 304.41
13 INT9131 Positive_regulation of Prkcg 3 431 0.70 130.8 302.41
14 INT5379 Gene_expression of Fos 10 656 0.78 255.5 292.54
15 INT5591 Regulation of Gene_expression of Fos 2 425 0.62 129.06 265.78
16 INT5972 Gene_expression of IL1B 1 948 0.78 510.91 263.97
17 INT5501 Regulation of Oprd1 1 283 0.62 55.1 249.9
18 INT738 Regulation of POMC 2 459 0.62 111.19 243.74
19 INT11377 Positive_regulation of Ngf 2 331 0.70 206.5 238
20 INT5597 Gene_expression of Pdyn 3 433 0.78 62.97 235.47
21 INT11009 Phosphorylation of Creb1 9 458 0.82 111.34 221.97
22 INT626 Localization of CALCA 3 289 0.81 125.39 221.15
23 INT6293 Gene_expression of Oprm1 2 312 0.78 48.73 215.61
24 INT4893 Gene_expression of Tacr1 5 366 0.78 129.67 213.92
25 INT16259 Positive_regulation of Bdnf 1 336 0.70 183.48 209.82
26 INT2391 Negative_regulation of PTGS1 1 501 0.59 207.62 205.6
27 INT9132 Negative_regulation of Prkcg 1 279 0.59 88.05 203.47
28 INT11313 Positive_regulation of Il6 4 526 0.70 331.27 201.59
29 INT94952 Positive_regulation of Mapk14 2 305 0.70 197.83 186.61
30 INT1429 Gene_expression of PDYN 3 308 0.78 61.33 175.65
31 INT739 Negative_regulation of POMC 1 358 0.59 102.28 166.77
32 INT6042 Binding of Oprm1 3 248 0.48 31.77 154.34
33 INT6108 Gene_expression of Npy 2 292 0.78 110.65 148.21
34 INT13353 Positive_regulation of Tnf 2 332 0.70 248.75 148.1
35 INT3300 Positive_regulation of Gene_expression of Calca 2 179 0.70 77.76 144.2
36 INT4658 Binding of OPRM1 2 188 0.48 25.96 136.24
37 INT2541 Binding of Calca 3 200 0.48 67.14 134.62
38 INT11012 Positive_regulation of Creb1 5 258 0.70 84.4 132
39 INT5380 Positive_regulation of Gene_expression of Fos 5 243 0.70 105.65 131.05
40 INT5931 Regulation of Oprm1 1 149 0.62 18.15 125.93
41 INT4824 Positive_regulation of Tacr1 4 169 0.70 66.1 123.46
42 INT11011 Positive_regulation of Phosphorylation of Creb1 2 190 0.70 49.25 112.01
43 INT49651 Gene_expression of Creb1 1 276 0.78 114.77 111.96
44 INT8413 Gene_expression of Ptgs1 2 248 0.78 110.17 108.58
45 INT12569 Localization of Oprd1 1 94 0.81 23.81 104.56
46 INT4742 Gene_expression of Tac1 5 177 0.78 69.99 102.66
47 INT89054 Positive_regulation of Gene_expression of Trpv1 5 156 0.70 90.78 102.03
48 INT97701 Phosphorylation of Mapk14 4 191 0.82 115.33 100.46
49 INT7944 Positive_regulation of Fos 1 193 0.70 60.69 98.31
50 INT29971 Gene_expression of Oprk1 1 126 0.78 35.32 93.97
51 INT11587 Gene_expression of CSF2 1 645 0.78 544.38 93.89
52 INT18755 Positive_regulation of Rvm 1 79 0.60 60 92.93
53 INT6437 Binding of YY1 1 154 0.47 26.3 90.46
54 INT18032 Positive_regulation of Oprk1 1 108 0.70 30.78 89.7
55 INT12763 Phosphorylation of Prkcg 1 167 0.82 38.91 89.63
56 INT7180 Negative_regulation of Trib3 3 180 0.51 68.48 88.01
57 INT75999 Gene_expression of BDNF 2 344 0.78 114.19 83.12
58 INT16254 Positive_regulation of Gene_expression of Ngf 5 144 0.70 80.61 82.08
59 INT10534 Positive_regulation of Trib3 2 209 0.60 78.75 81.48
60 INT12476 Negative_regulation of TRPV1 2 124 0.59 47.95 77.98
61 INT17546 Negative_regulation of Ngf 2 135 0.59 60.28 77.19
62 INT62374 Gene_expression of NGF 1 158 0.78 77.87 76.45
63 INT12001 Regulation of Ngf 2 97 0.62 54.64 76.25
64 INT5593 Positive_regulation of Gene_expression of Pdyn 2 114 0.70 29.1 74.46
65 INT10274 Positive_regulation of Il1b 1 123 0.70 79.76 73.56
66 INT58400 Negative_regulation of Tnf 1 182 0.59 129.97 71
67 INT6849 Localization of IL1B 2 229 0.81 112.56 69.63
68 INT451 Regulation of Oxt 1 142 0.62 22.07 69.42
69 INT7134 Localization of KNG1 1 127 0.79 65.73 67.97
70 INT19511 Localization of Il6 1 212 0.81 118.17 67.67
71 INT6824 Regulation of Gene_expression of Pdyn 1 114 0.62 9.48 66.73
72 INT5941 Gene_expression of Oxt 2 164 0.76 22.63 65.47
73 INT10706 Regulation of Il6 1 150 0.62 93.23 62.34
74 INT12175 Positive_regulation of PDYN 1 86 0.69 18.27 62.04
75 INT6623 Gene_expression of NA 1 231 0.78 45.78 59.36
76 INT62960 Gene_expression of P2rx2 2 149 0.77 58.31 59.16
77 INT48901 Negative_regulation of IL6 1 186 0.57 136.33 57.87
78 INT5017 Negative_regulation of Tacr1 1 76 0.58 17 57.07
79 INT8528 Negative_regulation of Gene_expression of Fos 1 100 0.59 41.15 55.6
80 INT7898 Gene_expression of Homer1 1 123 0.78 31.52 53.67
81 INT4985 Positive_regulation of Tac1 3 81 0.69 35.79 50.67
82 INT49520 Gene_expression of P2rx3 1 121 0.78 61.15 49.24
83 INT4345 Gene_expression of Gtf3a 1 157 0.67 80.75 48.47
84 INT5781 Gene_expression of Edn1 2 190 0.78 99.1 46
85 INT8465 Regulation of Ptgs1 1 100 0.57 36.03 44.41
86 INT88617 Positive_regulation of Gene_expression of Creb1 1 90 0.69 51.69 44.29
87 INT47683 Negative_regulation of Bdnf 1 92 0.59 47.53 43.55
88 INT27798 Gene_expression of Ntrk2 1 111 0.78 56.08 42.68
89 INT4887 Gene_expression of Tac4 1 70 0.77 11.66 40.97
90 INT16261 Transcription of Bdnf 2 101 0.72 49.41 40.64
91 INT107576 Gene_expression of Atf3 2 114 0.78 72.42 38.64
92 INT11854 Gene_expression of Il1rl1 1 57 0.77 30.19 38.25
93 INT30817 Gene_expression of Th 1 142 0.76 33.56 38.12
94 INT80075 Regulation of Gene_expression of Trpv1 2 55 0.62 32.42 36.88
95 INT6067 Positive_regulation of Positive_regulation of Oprd1 1 37 0.69 6.56 36.58
96 INT3971 Positive_regulation of Alb 1 175 0.70 98.46 36.45
97 INT14137 Localization of Oprm1 1 56 0.81 2.88 36.09
98 INT927 Gene_expression of Oxt 1 184 0.78 44.71 35.79
99 INT6484 Binding of IL1B 2 122 0.47 75.84 35.07
100 INT4892 Positive_regulation of Gene_expression of Tacr1 2 56 0.69 25.64 34.69
101 INT12161 Positive_regulation of P2rx2 1 70 0.69 34.22 34.4
102 INT666 Gene_expression of Jun 1 124 0.78 54.61 33.67
103 INT9347 Localization of Il1b 1 58 0.81 26.13 31.53
104 INT52690 Positive_regulation of Ptgs2 1 65 0.68 39.51 30.02
105 INT11010 Regulation of Phosphorylation of Creb1 2 52 0.62 7.26 29.04
106 INT55908 Gene_expression of Ngfr 1 74 0.78 34.46 28.8
107 INT48853 Positive_regulation of BDNF 1 82 0.69 43.92 27.99
108 INT21687 Positive_regulation of ras 3 143 0.58 97.34 27.31
109 INT5966 Localization of Il1a 2 50 0.78 22.91 26.54
110 INT5378 Regulation of Gene_expression of Fos 1 47 0.60 14.47 26.41
111 INT7899 Positive_regulation of Gene_expression of Homer1 1 41 0.70 7.29 25.98
112 INT50490 Regulation of PTGS2 1 80 0.48 39.51 25.85
113 INT11159 Gene_expression of EGFR 1 698 0.78 548.93 25.69
114 INT57874 Gene_expression of Egr1 3 113 0.78 68.46 24.95
115 INT48240 Binding of Ngf 1 46 0.46 23.51 24.42
116 INT129157 Positive_regulation of Atf3 3 48 0.69 35.42 22.87
117 INT6294 Regulation of Gene_expression of Oprm1 1 28 0.62 6.77 22.79
118 INT69322 Negative_regulation of MAPK14 5 70 0.54 42.92 22.71
119 INT106175 Positive_regulation of Positive_regulation of Creb1 2 37 0.70 13.89 22.46
120 INT5096 Positive_regulation of Gtf3a 1 79 0.60 42.26 20.62
121 INT45840 Positive_regulation of Gene_expression of Ptgs1 1 35 0.50 16.07 20.49
122 INT125411 Negative_regulation of Phosphorylation of Mapk14 2 31 0.57 18.55 19.98
123 INT74286 Regulation of Il10 2 42 0.44 28.06 19.44
124 INT69592 Positive_regulation of PSMD1 4 27 0.70 17.83 18.98
125 INT151747 Positive_regulation of PSMD2 5 26 0.68 17.48 17.89
126 INT7644 Positive_regulation of Gene_expression of PDYN 3 27 0.69 10.19 17.47
127 INT52358 Gene_expression of Cx3cr1 1 25 0.78 18.48 16.65
128 INT51576 Positive_regulation of Cxcl1 2 42 0.69 20.12 16.41
129 INT50932 Positive_regulation of Positive_regulation of Il6 1 36 0.69 24.9 16.12
130 INT2383 Positive_regulation of CP 1 33 0.67 25.41 15.38
131 INT121162 Gene_expression of Cx3cl1 7 22 0.78 11.56 14.59
132 INT11855 Positive_regulation of Gene_expression of Il1rl1 1 19 0.69 12.22 14.57
133 INT107575 Positive_regulation of Gene_expression of Atf3 1 25 0.69 27.37 14.55
134 INT57878 Positive_regulation of Gene_expression of Egr1 3 36 0.70 20.42 14.45
135 INT91913 Regulation of GRIN3B 1 16 0.61 11.48 14.44
136 INT6365 Localization of Edn1 3 56 0.81 18.84 13.83
137 INT27627 Binding of Rac1 1 41 0.41 22.88 13.68
138 INT49041 Transcription of Tacr1 1 25 0.72 12.52 12.8
139 INT55255 Positive_regulation of Localization of Il6 1 48 0.69 24.88 12.76
140 INT78234 Positive_regulation of Gene_expression of P2rx2 1 18 0.69 12.86 12.75
141 INT89404 Regulation of Negative_regulation of TNF 1 30 0.45 24.47 12.71
142 INT99587 Positive_regulation of Gene_expression of Oprk1 1 15 0.57 5.26 12.39
143 INT11766 Negative_regulation of H2-Ab1 2 15 0.43 5.27 12.32
144 INT3104 Negative_regulation of CGA 1 76 0.54 29.81 12.23
145 INT15756 Positive_regulation of Gene_expression of Jun 3 29 0.69 16.58 12.06
146 INT39587 Gene_expression of CP 1 42 0.65 31.48 11.87
147 INT127981 Gene_expression of Trpc1 1 25 0.77 10.51 11.67
148 INT118906 Regulation of Mapk14 1 21 0.44 17.95 11.63
149 INT4895 Positive_regulation of Gene_expression of Tac4 1 16 0.69 2.46 11.51
150 INT4723 Transcription of Tac1 1 26 0.71 8.33 11.18
151 INT2956 Binding of H2-Ab1 1 19 0.37 3.1 11.18
152 INT91932 Positive_regulation of Scn10a 2 18 0.67 10.39 10.9
153 INT8589 Positive_regulation of Positive_regulation of Tacr1 1 14 0.69 7.85 10.86
154 INT36453 Binding of ABCA1 1 48 0.45 19.9 10.84
155 INT78567 Positive_regulation of Gene_expression of Th 1 25 0.68 5.32 10.75
156 INT84077 Gene_expression of Hmox2 1 18 0.77 6.41 10.66
157 INT121161 Localization of Cx3cl1 2 14 0.75 10.07 10.61
158 INT64193 Regulation of Grin2a 1 19 0.54 2.98 10.31
159 INT33099 Negative_regulation of INSRR 1 32 0.40 13.82 9.85
160 INT57876 Positive_regulation of Egr1 1 46 0.70 25.6 9.41
161 INT147452 Gene_expression of ADCYAP1 1 14 0.77 12.54 9.28
162 INT109724 Phosphorylation of FSCN1 1 5 0.07 3.15 8.82
163 INT4984 Positive_regulation of Positive_regulation of Tac1 1 11 0.50 5.34 8.73
164 INT47682 Transcription of Ntrk2 1 19 0.69 6.32 8.6
165 INT22700 Positive_regulation of Gene_expression of Tac1 3 13 0.69 6.89 8.2
166 INT38971 Positive_regulation of Gene_expression of Gtf3a 1 27 0.60 18.25 7.77
167 INT87623 Gene_expression of PPT1 1 9 0.75 5.32 7.65
168 INT5431 Gene_expression of Glb1 1 23 0.75 6.53 7.58
169 INT109037 Regulation of Tens1 1 4 0.33 1.93 7.07
170 INT2838 Positive_regulation of Gene_expression of Oxt 1 27 0.67 6.25 6.83
171 INT114642 Negative_regulation of Positive_regulation of Creb1 3 12 0.57 2.32 6.75
172 INT99088 Gene_expression of HPT 1 5 0.59 9.1 6.72
173 INT48239 Binding of Gtf3a 1 52 0.33 23.14 6.45
174 INT48954 Positive_regulation of Localization of Il1b 1 13 0.53 8.16 6.44
175 INT48308 Binding of PLP1 3 7 0.48 9.59 6.09
176 INT14849 Binding of IgG-2a 1 12 0.39 5.96 6.06
177 INT52464 Negative_regulation of Bdkrb1 2 9 0.57 8.71 5.87
178 INT32611 Phosphorylation of Insr 1 13 0.80 4.18 5.77
179 INT62725 Regulation of GRIN2D 1 6 0.45 2.98 5.68
180 INT56047 Negative_regulation of Transcription of Bdnf 1 16 0.59 8.02 5.67
181 INT151748 Positive_regulation of Positive_regulation of PSMD2 2 4 0.49 4.45 5.35
182 INT128302 Localization of NeuN 1 24 0.73 9.81 5.27
183 INT105306 Regulation of Gene_expression of P2rx2 1 7 0.21 6.92 5.22
184 INT126047 Regulation of Phosphorylation of Mapk14 2 7 0.60 5.05 5.03
185 INT32256 Gene_expression of PLXNA3 1 11 0.75 7.8 4.92
186 INT5561 Negative_regulation of GRIN2D 1 10 0.50 2.46 4.88
187 INT8340 Negative_regulation of SHBG 1 49 0.57 35.96 4.73
188 INT148534 Gene_expression of Olr594 1 2 0.26 1.09 4.72
189 INT117936 Regulation of Gene_expression of Egr1 1 18 0.60 9.37 4.45
190 INT118230 Binding of Tnfrsf1a 1 15 0.42 7.63 4.39
191 INT64338 Negative_regulation of Hmox1 1 16 0.56 12.72 4.2
192 INT69591 Positive_regulation of Positive_regulation of PSMD1 2 2 0.50 3.06 3.99
193 INT149349 Regulation of Atf3 1 8 0.45 10 3.85
194 INT34720 Positive_regulation of SHBG 1 58 0.69 32.4 3.83
195 INT38560 Positive_regulation of SEMG1 1 13 0.60 4.37 3.81
196 INT117561 Positive_regulation of Transcription of Tac1 2 6 0.69 3.19 3.78
197 INT121106 Binding of Slmap 1 10 0.37 5.19 3.71
198 INT93120 Localization of Gfap 1 21 0.78 8.42 3.7
199 INT121159 Regulation of Cx3cl1 1 4 0.45 3.78 3.38
200 INT48726 Gene_expression of IGFBP1 1 27 0.67 9.45 3.36
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