J:J Transl Med

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT312686 CP Positive_regulation of CP Positive_regulation of CCL20 1 4 0.03 10.97 2.94
2 INT312690 CP Positive_regulation of CCL20 1 3 0.11 8.23 2.2
3 INT266391 Binding of Ager and S100a1 1 8 0.01 5.63 1.69
4 INT266406 Binding of APP and Ager 1 3 0.00 2.34 1.57
5 INT171264 TNF Positive_regulation of MMP1 2 1 0.10 2.05 0.95
6 INT219154 Binding of HMGB1 and TLR4 2 1 0.17 4.45 0.93
7 INT222979 Negative_regulation of Binding of COL1A1 and FN1 1 1 0.01 1.64 0.93
8 INT222978 Binding of COL1A1 and FN1 1 1 0.01 1.64 0.92
9 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 1 0.01 1.66 0.9
10 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 1 0.00 1.57 0.85
11 INT266408 Binding of HMGB1 and Ager 1 4 0.01 2.57 0.76
12 INT312691 CCR6 Regulation of PCA 1 1 0.20 2.76 0.74
13 INT312692 CCR6 Regulation of CCL20 1 1 0.29 2.42 0.73
14 INT312688 PCA Regulation of Localization of CCR6 1 1 0.20 2.67 0.67
15 INT312694 PCA Regulation of Localization of CP 1 1 0.05 2.65 0.66
16 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 2 0.21 1.68 0.63
17 INT178097 Binding of EDN1 and EDNRA 7 3 0.21 5.97 0.62
18 INT181084 Binding of S100a8 and S100a9 6 3 0.42 2.91 0.62
19 INT178087 EDN1 Positive_regulation of MMP13 2 1 0.23 1.58 0.59
20 INT266381 Positive_regulation of Ager Positive_regulation of Nfkb1 1 1 0.00 0.77 0.55
21 INT266376 Binding of Ager and Itgam 1 3 0.00 2.31 0.54
22 INT312693 Binding of CCR6 and CCL20 2 1 0.34 2.33 0.53
23 INT210225 Ptpn2 Positive_regulation of Gene_expression of Ifng 1 1 0.15 1.44 0.42
24 INT273893 ARSA Positive_regulation of HSD11B1 1 1 0.00 0.61 0.4
25 INT223829 Binding of GSTM1 and GSTP1 2 1 0.41 2.78 0.39
26 INT266393 Binding of Ager and Fn1 1 1 0.00 0.82 0.39
27 INT266382 Binding of Col4a1 and Fn1 1 1 0.00 0.82 0.39
28 INT266397 Binding of Ager and Col4a1 1 1 0.00 0.81 0.38
29 INT266419 HMGB1 Positive_regulation of Ager 1 3 0.01 1.37 0.37
30 INT178217 IFNA1 Regulation of Cxcl10 1 1 0.01 0.86 0.37
31 INT178218 IFNA1 Regulation of Tlr7 1 1 0.04 0.87 0.37
32 INT330464 Setd1a Regulation of Gene_expression of RT1-CE1 1 1 0.00 0.47 0.35
33 INT266402 Binding of S100P and Ager 1 3 0.00 2.25 0.35
34 INT161796 Binding of ECE1 and EDN1 2 2 0.21 2.23 0.34
35 INT323352 Binding of F8 and VWF 5 1 0.08 2.22 0.33
36 INT222973 NFKBIB Negative_regulation of NFKB2 Negative_regulation of IL6 1 1 0.00 1.6 0.33
37 INT266383 Binding of Ager and S100b 1 4 0.01 3.48 0.33
38 INT222974 NFKBIB Negative_regulation of NFKB2 Negative_regulation of ICAM1 1 1 0.00 1.6 0.33
39 INT340616 COL4A4 Regulation of MMP9 1 1 0.12 0.95 0.32
40 INT222976 NFKBIB Negative_regulation of NFKB2 1 1 0.01 1.58 0.32
41 INT340615 COL4A4 Regulation of MMP2 1 1 0.11 0.95 0.32
42 INT330462 Ngf Positive_regulation of Gene_expression of Adh1 1 1 0.01 0.57 0.31
43 INT266375 S100b Positive_regulation of Ager 1 2 0.02 1.8 0.31
44 INT219151 IL18 Positive_regulation of CASP1 1 1 0.01 1.05 0.3
45 INT178102 EDNRA Positive_regulation of Localization of TIMP1 1 1 0.06 0.97 0.28
46 INT178088 EDNRA Positive_regulation of Transcription of TIMP1 1 1 0.06 0.97 0.28
47 INT327366 Binding of Fap and Ttr 1 2 0.33 2.9 0.28
48 INT219156 NLRP3 Positive_regulation of IL1B 1 1 0.01 1.03 0.27
49 INT71642 Binding of HLA-A and PMEL 2 1 0.20 1.05 0.26
50 INT222986 PTPRC Positive_regulation of SMN1 1 1 0.01 0.46 0.26
51 INT219194 Nlrp3 Positive_regulation of IL1B 1 1 0.04 1.03 0.26
52 INT219193 Nlrp3 Positive_regulation of Positive_regulation of NLRP3 1 1 0.24 1.03 0.26
53 INT222975 PTPRC Positive_regulation of VIM 1 1 0.05 0.46 0.26
54 INT222981 TGFB1 Positive_regulation of Gene_expression of MMRN1 1 1 0.09 1.62 0.25
55 INT225652 Gene_expression of IL4 Positive_regulation of Positive_regulation of IL12A 1 1 0.06 1.2 0.25
56 INT178095 EDN1 Positive_regulation of MMP3 1 1 0.04 0.88 0.24
57 INT178076 EDN1 Positive_regulation of MMP2 1 1 0.04 0.88 0.24
58 INT178085 EDN1 Positive_regulation of MMP7 1 1 0.06 0.89 0.24
59 INT178141 EDN1 Positive_regulation of Timp1 1 1 0.30 0.89 0.24
60 INT178075 EDN1 Positive_regulation of PLAU 1 1 0.06 0.95 0.24
61 INT178104 EDN1 Positive_regulation of Localization of TIMP1 1 1 0.05 0.83 0.24
62 INT178094 Positive_regulation of EDN1 Positive_regulation of PLAU 1 1 0.06 0.95 0.24
63 INT178142 EDN1 Positive_regulation of Localization of Timp1 1 1 0.28 0.89 0.24
64 INT178077 EDN1 Positive_regulation of MMP9 1 1 0.06 0.88 0.24
65 INT266421 Binding of HMGB1 and Il1 1 1 0.02 0.37 0.24
66 INT346455 IFNA1 Regulation of HCC 1 2 0.02 1.64 0.23
67 INT266418 Binding of HMGB1 and Tlr4 1 1 0.09 0.37 0.23
68 INT330463 Setd1a Positive_regulation of Regulation of Adh1 1 1 0.00 0.09 0.23
69 INT238802 Binding of Ager and Renbp 6 3 0.02 6.46 0.22
70 INT312689 Binding of PCA and CCL20 1 1 0.15 1.27 0.22
71 INT245866 Binding of VEGFA and Fgf1 1 1 0.07 0.52 0.22
72 INT303606 Binding of IL18 and SOAT1 1 1 0.05 0.52 0.22
73 INT266405 S100b Positive_regulation of Gene_expression of TFAM 1 1 0.00 1.02 0.21
74 INT266380 Binding of Tlr2 and Il1 1 1 0.01 0.76 0.21
75 INT269180 LEP Positive_regulation of Localization of TNF 1 1 0.01 0.99 0.21
76 INT223828 Binding of GSTP1 and MAPK8 1 2 0.06 1.8 0.21
77 INT346458 ROS1 Regulation of Localization of TGFB1 1 1 0.00 1.71 0.21
78 INT266401 S100b Positive_regulation of S100b Positive_regulation of Ager 1 1 0.01 0.96 0.21
79 INT219153 IL6 Positive_regulation of IL23A 1 1 0.02 0.45 0.21
80 INT174861 Binding of FGF2 and VEGFA 1 1 0.34 0.59 0.2
81 INT266423 Binding of HMGB1 and Mapk3 1 1 0.04 0.9 0.2
82 INT178059 Binding of EDN1 and EDNRA Positive_regulation of Phosphorylation of PXN 1 1 0.04 0.83 0.2
83 INT266410 Binding of HMGB1 and Mapk14 1 1 0.03 0.91 0.2
84 INT178074 EDN1 Positive_regulation of Phosphorylation of PXN 1 1 0.05 0.82 0.2
85 INT266416 Binding of HMGB1 and Mapk1 1 1 0.06 0.9 0.2
86 INT178086 Binding of EDNRA and PTK2 1 1 0.07 0.82 0.2
87 INT266414 Binding of HMGB1 and Mapk8 1 1 0.03 0.91 0.2
88 INT266404 Binding of HMGB1 and Thbd 1 1 0.06 0.3 0.2
89 INT266646 HMOX2 Regulation of Gene_expression of Hmox1 1 1 0.00 0.87 0.2
90 INT225649 IL4 Positive_regulation of Localization of DCPS 1 1 0.02 1.03 0.19
91 INT286965 Binding of STAT3 and FOXP3 1 3 0.27 1.84 0.19
92 INT322237 Binding of Agtrap and Hcm 1 3 0.14 2.3 0.19
93 INT346459 Binding of RNASE1 and ROS1 1 1 0.06 1.42 0.18
94 INT198700 Binding of DSG3 and Pv 1 2 0.15 1.45 0.18
95 INT178092 EDN3 Positive_regulation of PTK2 1 1 0.01 1.02 0.17
96 INT178073 EDN1 Positive_regulation of PTK2 1 1 0.03 1.02 0.17
97 INT266417 Binding of TGM2 and S100a11 1 1 0.01 0.86 0.16
98 INT266422 HMGB1 Positive_regulation of Binding of Ager 1 1 0.01 0.92 0.16
99 INT178079 EDN1 Positive_regulation of Positive_regulation of AKT1 1 1 0.05 0.91 0.16
100 INT329796 TICAM1 Positive_regulation of IFNA1 2 1 0.02 0.89 0.15
101 INT224797 IL12A Regulation of Gene_expression of TNF 1 1 0.26 1.59 0.15
102 INT298717 Fgf2 Positive_regulation of Gene_expression of PDGFA 1 1 0.01 0.23 0.15
103 INT325952 Gene_expression of Ezr Positive_regulation of Mapk1 1 2 0.02 1.69 0.15
104 INT266412 Binding of S100A12 and Ager 1 1 0.01 1.03 0.15
105 INT298716 Ngf Positive_regulation of Gene_expression of PDGFA 1 1 0.01 0.22 0.15
106 INT266377 Binding of S100a11 and Trp53 1 1 0.02 0.89 0.15
107 INT273891 WDTC1 Positive_regulation of Gene_expression of SELP 1 1 0.00 0.45 0.15
108 INT346451 Positive_regulation of Binding of IFNA1 and DDX58 1 1 0.01 0.54 0.15
109 INT346450 Binding of IFNA1 and DDX58 1 1 0.01 0.54 0.15
110 INT266413 Positive_regulation of Binding of HMGB1 and Col4a1 1 1 0.02 1.05 0.14
111 INT266411 Binding of HMGB1 and Col4a1 1 1 0.01 1.05 0.14
112 INT330467 IL12A Positive_regulation of Localization of TH1L 1 1 0.16 0.3 0.14
113 INT298715 Igf1 Positive_regulation of Gene_expression of PDGFA 1 1 0.00 0.22 0.14
114 INT346500 TLR3 Positive_regulation of Nfkb1 1 1 0.01 0.49 0.13
115 INT346501 MYD88 Positive_regulation of Nfkb1 1 1 0.01 0.5 0.13
116 INT266403 Negative_regulation of Binding of S100P and Ager 1 1 0.00 0.74 0.13
117 INT178083 EDN1 Positive_regulation of Gene_expression of VEGFA 1 2 0.09 1.8 0.13
118 INT178101 EDN1 Negative_regulation of Phosphorylation of BCL2 1 1 0.03 1 0.12
119 INT227701 Tlx2 Positive_regulation of Regulation of SSRP1 1 1 0.00 0.69 0.12
120 INT219157 Binding of KLRB1 and CLEC2D 1 1 0.02 0.41 0.12
121 INT266384 Binding of Ager and S100a6 1 2 0.01 1.32 0.11
122 INT219152 NLRP3 Positive_regulation of Positive_regulation of CASP1 1 1 0.02 0.83 0.1
123 INT266386 Binding of S100a1 and Trp53 1 2 0.03 0.64 0.1
124 INT286969 IL2 Regulation of Gene_expression of FOXP3 1 2 0.04 1.05 0.1
125 INT266385 S100a6 Positive_regulation of Ager 1 1 0.01 0.84 0.1
126 INT266373 Itgam Positive_regulation of Ager 1 1 0.01 0.84 0.1
127 INT266396 Binding of Ager and S100a4 1 1 0.01 0.59 0.1
128 INT219155 Binding of HLA-G and LILRB2 1 1 0.15 0.23 0.1
129 INT223827 MAPK8 Positive_regulation of Gene_expression of GSTP1 1 1 0.12 0.88 0.1
130 INT273892 LPA Positive_regulation of ALB 1 1 0.01 0.95 0.1
131 INT286963 EGF Positive_regulation of Gene_expression of STAT3 1 1 0.03 0.57 0.1
132 INT282094 Apoa2 Negative_regulation of BCL2 1 1 0.06 1.15 0.09
133 INT219150 Binding of CXCL11 and CXCR7 1 1 0.09 1.77 0.09
134 INT286964 IL23A Positive_regulation of STAT3 1 1 0.05 0.57 0.09
135 INT222984 TNF Positive_regulation of Positive_regulation of FN1 1 1 0.05 0.72 0.09
136 INT322258 Binding of Agtrap and l5H1 1 1 0.40 0.62 0.09
137 INT178089 Binding of EDNRA and Positive_regulation of PTK2 1 1 0.09 0.74 0.09
138 INT343794 Binding of F8 and PTPRC 1 1 0.00 0.69 0.09
139 INT178072 Gene_expression of EDNRB Positive_regulation of EDN3 1 1 0.05 1.11 0.08
140 INT178100 Gene_expression of EDNRB Positive_regulation of EDN1 1 1 0.17 1.11 0.08
141 INT178081 Negative_regulation of EDN1 Positive_regulation of HIF1A 1 1 0.04 1.18 0.08
142 INT266952 Binding of Aspscr1 and Ap2s1 1 1 0.01 0.51 0.08
143 INT178078 Positive_regulation of Binding of DBP and HIF1A 1 1 0.00 1 0.08
144 INT178080 EDN1 Positive_regulation of HIF1A 1 1 0.05 1.05 0.08
145 INT178060 EDN1 Positive_regulation of EDN1 Positive_regulation of HIF1A 1 1 0.03 1.13 0.08
146 INT222983 TNF Positive_regulation of Positive_regulation of COL1A1 1 1 0.01 0.71 0.08
147 INT266394 Binding of S100a4 and Trp53 1 1 0.03 0.59 0.08
148 INT343792 Binding of TCF21 and CORO7 1 2 0.01 0.51 0.07
149 INT178103 Binding of DBP and HIF1A 1 1 0.00 0.99 0.07
150 INT266389 Binding of C2 and S100a6 1 1 0.04 0.5 0.07
151 INT266390 Binding of S100a6 and Trp53 1 1 0.04 0.51 0.07
152 INT225650 DCPS Positive_regulation of PDHA1 1 1 0.00 0.41 0.07
153 INT178093 EDN3 Positive_regulation of Gene_expression of EDNRB 1 1 0.05 1.01 0.07
154 INT325954 Binding of Cttn and Ezr 1 1 0.22 1.61 0.07
155 INT178207 Laq1 Negative_regulation of Pigl 1 1 0.00 1.26 0.07
156 INT178096 EDN1 Positive_regulation of Gene_expression of EDNRB 1 1 0.17 1.01 0.07
157 INT266398 Binding of S100b and Trp53 1 1 0.06 0.92 0.07
158 INT346499 Mal Positive_regulation of TICAM1 1 1 0.06 0.66 0.07
159 INT260968 Binding of G8 and Gd 1 2 0.01 0.37 0.06
160 INT286955 IL2 Positive_regulation of Binding of STAT3 and FOXP3 1 1 0.03 0.63 0.06
161 INT346452 TLR3 Positive_regulation of TBK1 1 1 0.03 0.45 0.06
162 INT178084 EDNRA Positive_regulation of Phosphorylation of GJA1 1 1 0.10 0.88 0.06
163 INT286966 IL2 Positive_regulation of Binding of STAT3 1 1 0.04 0.5 0.06
164 INT266388 S100a6 Negative_regulation of Mapk8 1 1 0.03 0.49 0.06
165 INT346456 TLR3 Positive_regulation of IKBKE 1 1 0.02 0.45 0.06
166 INT346449 TICAM1 Positive_regulation of TBK1 1 1 0.01 0.45 0.06
167 INT178090 EDN1 Positive_regulation of Phosphorylation of GJA1 1 1 0.09 0.88 0.06
168 INT223825 GSTP1 Negative_regulation of MAPK8 1 2 0.11 1.53 0.06
169 INT346454 TICAM1 Positive_regulation of IKBKE 1 1 0.01 0.45 0.06
170 INT266374 Binding of S100a1 and S100a9 1 1 0.09 0.17 0.05
171 INT290676 Binding of CEACAM3 and MUC16 1 1 0.10 0.7 0.05
172 INT346457 IRF3 Positive_regulation of IFNA1 1 1 0.03 0.56 0.05
173 INT308291 LY6E Regulation of EPC1 1 1 0.00 0 0.05
174 INT308292 CSF2 Positive_regulation of EPC1 1 1 0.10 0 0.05
175 INT266387 Binding of S100a1 and S100a8 1 1 0.09 0.17 0.05
176 INT219149 FBXO8 Positive_regulation of Localization of IL10 1 1 0.01 0.14 0.05
177 INT329102 Binding of CD4 and HLA-DQA2 2 1 0.04 0.92 0.04
178 INT188737 Egfr Positive_regulation of EGFR 1 1 0.21 0.6 0.04
179 INT178091 EDN1 Positive_regulation of Gene_expression of PTGER2 1 1 0.01 0.74 0.04
180 INT222982 TNF Positive_regulation of Localization of FN1 1 1 0.05 0.56 0.04
181 INT178098 EDN1 Positive_regulation of Transcription of VEGFA 1 1 0.08 0.76 0.04
182 INT286968 Positive_regulation of STAT3 Regulation of Gene_expression of CD4 1 1 0.16 0.44 0.04
183 INT266379 S100a8 Positive_regulation of Ager 1 1 0.01 0.3 0.04
184 INT308290 LY6E Positive_regulation of EPC1 1 2 0.00 0 0.04
185 INT266372 Binding of S100a1 and S100a4 1 1 0.11 0.15 0.04
186 INT286967 Positive_regulation of STAT3 Regulation of Gene_expression of FOXP3 1 1 0.35 0.44 0.04
187 INT178503 Binding of Cd36 and ecs 1 1 0.01 0.34 0.04
188 INT188735 EGFR Positive_regulation of Egfr 1 1 0.21 0.6 0.04
189 INT178082 EDN1 Positive_regulation of VEGFA 1 1 0.08 0.77 0.04
190 INT266392 S100a9 Positive_regulation of Ager 1 1 0.01 0.3 0.04
191 INT219195 Binding of PDC and fc 1 1 0.01 0.24 0.04
192 INT188732 EGFR Positive_regulation of Gene_expression of Egfr 1 1 0.21 0.6 0.04
193 INT286962 IL2 Regulation of Gene_expression of CD4 1 1 0.01 0.45 0.04
194 INT178501 Angpt1 Positive_regulation of Tek 1 1 0.06 0.78 0.04
195 INT222980 TNF Positive_regulation of Localization of COL1A1 1 1 0.01 0.56 0.04
196 INT205480 Egfr Positive_regulation of Stat3 5 1 0.58 4.11 0.03
197 INT223826 GSTM1 Negative_regulation of MAP3K5 1 1 0.02 0.71 0.03
198 INT223824 Binding of GSTM1 and MAP3K5 1 1 0.02 0.68 0.03
199 INT188736 Egfr Regulation of IGLV3-1 1 1 0.46 0.59 0.03
200 INT227700 MET Positive_regulation of Stat3 1 1 0.04 0.8 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 22 3152 0.78 2515.62 929.82
2 INT443 Localization of POMC 1 1020 0.81 284.52 443.17
3 INT9238 Gene_expression of IL6 15 1575 0.78 1135.66 424.22
4 INT16260 Gene_expression of Bdnf 4 671 0.78 283.44 339.1
5 INT5059 Positive_regulation of TNF 3 1050 0.70 896.51 322.81
6 INT5680 Gene_expression of Ngf 13 530 0.78 264.29 310.56
7 INT9158 Gene_expression of Tnf 2 722 0.78 522.01 277.68
8 INT49750 Negative_regulation of CPOX 3 735 0.58 360.06 274.19
9 INT6852 Localization of TNF 5 883 0.81 705.95 270.84
10 INT10832 Gene_expression of IL8 15 1050 0.78 698.72 270
11 INT9659 Gene_expression of Il6 8 991 0.78 715.11 265.57
12 INT5972 Gene_expression of IL1B 2 948 0.78 510.91 263.97
13 INT68684 Gene_expression of VEGFA 109 2371 0.78 1742.52 259.2
14 INT16868 Gene_expression of Il6 4 807 0.78 499.48 256.57
15 INT11377 Positive_regulation of Ngf 5 331 0.70 206.5 238
16 INT95787 Positive_regulation of Mapk1 2 568 0.70 226.51 220.94
17 INT6481 Binding of TNF 2 624 0.48 510.2 214.82
18 INT22548 Positive_regulation of Casp3 1 483 0.70 258.78 213.07
19 INT6482 Positive_regulation of Gene_expression of TNF 3 659 0.70 569.88 210
20 INT16259 Positive_regulation of Bdnf 1 336 0.70 183.48 209.82
21 INT2391 Negative_regulation of PTGS1 2 501 0.59 207.62 205.6
22 INT50670 Gene_expression of CPOX 10 763 0.76 442.13 195.02
23 INT6488 Gene_expression of Tnf 3 484 0.78 339.61 191.58
24 INT10194 Positive_regulation of IL6 10 702 0.70 600.62 183.38
25 INT49441 Negative_regulation of Cpox 2 494 0.59 303.22 177.46
26 INT19472 Gene_expression of Il1 4 554 0.76 419.75 175.35
27 INT15516 Gene_expression of Crp 1 711 0.77 615.33 173.09
28 INT867 Gene_expression of IFNA1 28 930 0.78 594.85 168.03
29 INT55879 Gene_expression of CCL2 5 421 0.78 240.74 166.02
30 INT120811 Gene_expression of Gopc 7 1174 0.59 428.49 150.55
31 INT15515 Positive_regulation of Crp 1 700 0.70 604.24 150.15
32 INT5116 Gene_expression of IL2 6 670 0.78 291.13 146.69
33 INT812 Localization of INS 1 1026 0.81 515.6 145.31
34 INT60694 Gene_expression of Il10 14 567 0.78 369.48 143.69
35 INT48953 Positive_regulation of Nos2 2 486 0.70 239.85 131.87
36 INT49439 Gene_expression of Cpox 6 508 0.73 326.97 130.17
37 INT65600 Positive_regulation of Casp3 2 376 0.70 198.44 128.03
38 INT7533 Gene_expression of Tlr4 2 720 0.78 343.22 121.57
39 INT8243 Positive_regulation of Il6 6 451 0.70 358.24 119.28
40 INT17612 Gene_expression of CRP 7 676 0.78 580.61 119.03
41 INT92669 Gene_expression of Bdnf 2 309 0.78 178.26 116.68
42 INT62124 Gene_expression of NOS1 2 444 0.78 218.08 114.85
43 INT48593 Positive_regulation of NOS1 1 420 0.68 226.15 114.71
44 INT20374 Gene_expression of Il4 1 515 0.76 306.15 114.12
45 INT11051 Positive_regulation of Gene_expression of IL6 6 415 0.69 319.21 109.3
46 INT27096 Positive_regulation of Nfkb1 3 325 0.70 195.11 109.06
47 INT60526 Gene_expression of IL10 16 449 0.78 292.71 107.84
48 INT3038 Gene_expression of INS 1 1583 0.78 1174.16 107.01
49 INT12082 Localization of IL6 1 365 0.81 241.78 105.78
50 INT69440 Gene_expression of ROS1 5 752 0.78 477.64 103.83
51 INT18009 Positive_regulation of CRP 2 518 0.70 553.03 103.74
52 INT90091 Gene_expression of GOPC 4 967 0.67 366.22 103.6
53 INT10838 Positive_regulation of IL8 4 381 0.70 295.51 101.62
54 INT11381 Positive_regulation of IL1B 2 330 0.70 209.31 100.9
55 INT1760 Gene_expression of PTGER2 2 524 0.57 226.94 96.4
56 INT11587 Gene_expression of CSF2 1 645 0.78 544.38 93.89
57 INT77435 Positive_regulation of Nos2 1 343 0.70 208.49 91.43
58 INT86024 Gene_expression of PPARA 2 736 0.78 497.93 91.14
59 INT9516 Negative_regulation of Gabrg1 1 149 0.53 27.83 91.02
60 INT71789 Positive_regulation of MAPK1 1 396 0.70 234.44 89.27
61 INT48408 Gene_expression of ICAM1 2 494 0.78 340.08 88.6
62 INT54571 Positive_regulation of NFKB1 1 263 0.70 138.99 87.32
63 INT82448 Gene_expression of S100a8 4 246 0.77 236.72 84.02
64 INT92434 Phosphorylation of Mapk1 1 287 0.82 91.65 83.46
65 INT68682 Positive_regulation of VEGFA 17 640 0.70 454.14 81.65
66 INT56291 Gene_expression of Ros1 2 503 0.63 274.12 81.5
67 INT749 Gene_expression of HLA-B 1 341 0.75 224.12 77.37
68 INT60691 Gene_expression of Il12a 7 331 0.78 208.03 75.96
69 INT5056 Gene_expression of IFNG 2 216 0.78 137.52 74.57
70 INT56298 Gene_expression of IL4 6 306 0.78 182.18 72.92
71 INT39565 Gene_expression of Ptger2 2 424 0.75 229.28 72.68
72 INT12720 Positive_regulation of Il1 3 246 0.70 195.97 72.05
73 INT58400 Negative_regulation of Tnf 1 182 0.59 129.97 71
74 INT49995 Positive_regulation of Gene_expression of Tnf 1 187 0.70 125.07 70.54
75 INT10837 Positive_regulation of Gene_expression of IL8 6 294 0.70 190.08 70.34
76 INT79494 Positive_regulation of Gene_expression of VEGFA 33 577 0.70 442.94 69.73
77 INT170332 Gene_expression of IFN1@ 13 477 0.75 275.21 69.65
78 INT8357 Gene_expression of KNG1 1 153 0.75 77.26 68.66
79 INT7534 Gene_expression of Ifng 1 193 0.78 111.02 68.6
80 INT102546 Gene_expression of Ccl2 2 197 0.78 192.8 67.41
81 INT5374 Gene_expression of Esr1 3 412 0.77 263.89 67.34
82 INT6486 Positive_regulation of Tnf 3 168 0.70 123.47 66.05
83 INT3375 Gene_expression of IGHE 1 535 0.77 387.47 65.46
84 INT1425 Gene_expression of Rbm39 1 143 0.58 51.32 65.44
85 INT11807 Gene_expression of Il2 5 266 0.78 112 64.97
86 INT11937 Localization of Il6 1 228 0.81 139.83 64.39
87 INT822 Gene_expression of ESR1 4 529 0.78 302.16 63.64
88 INT9657 Positive_regulation of Gene_expression of Il6 1 237 0.70 180.45 63.6
89 INT1951 Positive_regulation of Tlr4 1 345 0.70 176.99 62.42
90 INT67981 Positive_regulation of CCL2 4 165 0.70 136.84 61.85
91 INT11318 Gene_expression of Gtf3a 1 274 0.52 183.82 60.89
92 INT5058 Positive_regulation of IFNA1 12 356 0.70 245.75 60.52
93 INT9196 Gene_expression of PTGS1 1 215 0.77 96.99 60.5
94 INT14740 Gene_expression of TGFB1 6 272 0.78 168.48 60.18
95 INT1759 Gene_expression of TIMP1 1 267 0.77 133.87 59.29
96 INT16258 Gene_expression of Ntf3 4 121 0.78 53.93 59.03
97 INT169926 Positive_regulation of Gopc 5 416 0.46 157.8 58.67
98 INT48901 Negative_regulation of IL6 1 186 0.57 136.33 57.87
99 INT73048 Gene_expression of MMP9 14 268 0.77 159.75 57.81
100 INT31116 Gene_expression of Casp3 2 192 0.78 78.21 57.43
101 INT96937 Gene_expression of Mmp9 5 191 0.75 150.3 56.01
102 INT78899 Gene_expression of CCL5 1 155 0.77 84.02 55.09
103 INT251 Regulation of INS 1 398 0.62 232.47 55.04
104 INT63975 Positive_regulation of Il10 2 175 0.68 134.13 54.69
105 INT117223 Gene_expression of TLR4 1 348 0.78 206.18 54.42
106 INT49993 Positive_regulation of Gene_expression of Il6 1 149 0.70 88.07 53.78
107 INT9234 Negative_regulation of Gene_expression of IL6 2 171 0.59 101.61 53.15
108 INT62543 Gene_expression of Icam1 4 231 0.78 187.58 52.71
109 INT22112 Positive_regulation of Localization of TNF 2 164 0.70 115.66 52.18
110 INT66040 Positive_regulation of Bdnf 2 114 0.69 67.67 51.81
111 INT19775 Localization of Il1 1 183 0.78 145.5 50.91
112 INT6473 Positive_regulation of Gene_expression of IL1B 1 204 0.70 117.23 50.86
113 INT9210 Regulation of IL6 1 166 0.62 125.61 49.95
114 INT66029 Negative_regulation of Tnf 1 100 0.59 84.28 48.16
115 INT62426 Gene_expression of Mc1r 1 127 0.78 42.99 48.01
116 INT106525 Phosphorylation of Akt1 1 436 0.82 183.81 47.82
117 INT671 Positive_regulation of Cea 5 221 0.69 164.5 47.79
118 INT26500 Gene_expression of MMP2 16 201 0.78 110.57 46.9
119 INT1322 Positive_regulation of Localization of INS 1 293 0.70 120.86 45.98
120 INT81498 Positive_regulation of Gene_expression of CCL2 2 107 0.70 53.89 45.22
121 INT16364 Gene_expression of HLA-DRA 1 234 0.78 118.81 45.01
122 INT18522 Positive_regulation of Gene_expression of IFNA1 8 248 0.67 160.85 44.87
123 INT80124 Negative_regulation of VEGFA 6 450 0.58 311.19 44.53
124 INT19078 Binding of Ngf 2 78 0.48 31.03 44.33
125 INT109910 Gene_expression of CCL16 1 104 0.74 76.1 43.97
126 INT25610 Positive_regulation of Gene_expression of Il1 1 136 0.67 104.43 43.86
127 INT73502 Positive_regulation of IL10 3 154 0.69 124.87 43.5
128 INT25383 Gene_expression of Csf2 15 222 0.76 152.93 43.32
129 INT60695 Positive_regulation of Gene_expression of Il10 3 154 0.70 120.28 43.07
130 INT115384 Positive_regulation of Mmp9 2 121 0.68 94.74 43.02
131 INT52531 Gene_expression of Nfkb1 1 153 0.75 82.84 42.9
132 INT157666 Positive_regulation of GOPC 3 335 0.60 120.19 42.75
133 INT50957 Negative_regulation of Il6 1 134 0.59 79.08 42.67
134 INT170054 Negative_regulation of Gopc 2 280 0.38 117.89 42.4
135 INT61619 Gene_expression of IL12A 19 194 0.77 146.07 41.97
136 INT13556 Gene_expression of CD4 9 367 0.78 230.82 41.74
137 INT69437 Positive_regulation of ROS1 1 328 0.58 222.83 40.56
138 INT97596 Localization of S100a8 1 94 0.78 90.69 40.41
139 INT3758 Gene_expression of ALB 3 326 0.78 184.65 38.75
140 INT11439 Positive_regulation of Csf2 2 105 0.69 62.63 37.77
141 INT50673 Positive_regulation of Gene_expression of CPOX 1 156 0.54 97.31 37.03
142 INT80690 Positive_regulation of MAPK8 3 223 0.68 125.63 36.75
143 INT9082 Positive_regulation of ESR1 2 238 0.69 148.51 36.69
144 INT101992 Localization of VEGFA 8 413 0.81 258.23 36.15
145 INT70437 Negative_regulation of Mdk 1 115 0.57 41.03 35.72
146 INT59466 Gene_expression of ISYNA1 4 204 0.77 112.57 35.48
147 INT1705 Gene_expression of pCA 6 126 0.65 88.65 34.81
148 INT20380 Gene_expression of Il5 1 172 0.78 104.75 34.78
149 INT6105 Positive_regulation of IL2 4 133 0.69 82.76 34.67
150 INT7675 Gene_expression of ENG 5 146 0.77 45.35 34.6
151 INT1624 Gene_expression of Cea 14 212 0.76 180.44 34.21
152 INT8905 Gene_expression of EDN1 21 215 0.78 157.1 34.19
153 INT14559 Gene_expression of Igf1 2 254 0.78 112 34.17
154 INT74563 Positive_regulation of Gene_expression of ROS1 1 258 0.61 168.18 34.08
155 INT49214 Gene_expression of Cd4 3 269 0.78 154.22 34.05
156 INT81289 Positive_regulation of Gene_expression of Tlr4 1 192 0.69 104.5 33.89
157 INT11325 Gene_expression of HLA-E 7 209 0.76 98.05 33.72
158 INT2732 Gene_expression of VIP 1 74 0.78 24.57 33.72
159 INT666 Gene_expression of Jun 1 124 0.78 54.61 33.67
160 INT52350 Gene_expression of CD14 1 184 0.75 71.37 33.13
161 INT9694 Positive_regulation of Csf2 3 102 0.68 70.09 33.07
162 INT6302 Binding of IFNA1 7 196 0.48 133.85 32.73
163 INT65698 Localization of CCL2 5 118 0.81 77.54 32.69
164 INT8915 Gene_expression of Igf1 1 199 0.78 78.58 32.51
165 INT14823 Gene_expression of MET 4 103 0.75 51.92 32.48
166 INT62830 Gene_expression of VCAM1 1 149 0.78 125.23 32.4
167 INT73498 Gene_expression of IL13 1 117 0.44 83.85 32.26
168 INT22939 Gene_expression of Csf2 2 164 0.78 85.1 32.22
169 INT96913 Positive_regulation of Mapk8 1 179 0.69 130.44 32.2
170 INT73982 Gene_expression of Hmox1 3 141 0.78 119.43 32.17
171 INT114881 Gene_expression of Akt1 4 227 0.78 102.49 31.81
172 INT88318 Gene_expression of CXCR4 4 208 0.77 189.67 31.72
173 INT48693 Regulation of VEGFA 7 268 0.62 191.88 31.52
174 INT94388 Gene_expression of GDF15 5 124 0.77 79.48 31.42
175 INT56809 Binding of Tlr4 5 184 0.48 106.02 31.18
176 INT99688 Negative_regulation of Gene_expression of VEGFA 10 274 0.58 201.8 31.1
177 INT65960 Gene_expression of BCL2 3 352 0.78 312.03 30.73
178 INT34729 Positive_regulation of IFN1@ 5 233 0.67 128.04 30.38
179 INT77652 Negative_regulation of Gene_expression of IL8 1 99 0.59 67.57 30.21
180 INT23435 Positive_regulation of NGF 1 54 0.70 32.41 30.11
181 INT90792 Localization of Il10 6 144 0.80 87.88 30.03
182 INT65597 Negative_regulation of Casp3 1 69 0.59 39.19 29.32
183 INT86437 Binding of IL6 1 154 0.48 121.22 29.3
184 INT15174 Gene_expression of Itgam 1 238 0.73 104.92 29.26
185 INT9650 Gene_expression of LPA 2 141 0.75 104.57 29
186 INT3841 Gene_expression of FCGR3B 3 117 0.75 58.99 28.87
187 INT28361 Gene_expression of TP53 9 443 0.78 384.86 28.8
188 INT15610 Localization of GOPC 2 223 0.65 68.26 28.7
189 INT65598 Negative_regulation of Positive_regulation of Casp3 1 45 0.59 18.36 28.59
190 INT8097 Gene_expression of EGF 2 122 0.77 75.94 28.47
191 INT3286 Positive_regulation of Gpt 1 90 0.69 45.08 28.34
192 INT91775 Gene_expression of Slc6a4 3 102 0.78 26.45 28.23
193 INT22045 Gene_expression of IRF6 1 158 0.75 58.07 27.81
194 INT55737 Positive_regulation of MMP2 3 101 0.68 59.11 27.71
195 INT133876 Positive_regulation of Gene_expression of Ros1 1 141 0.32 75.55 27.45
196 INT37296 Binding of Esr1 1 117 0.43 62.51 27.33
197 INT10799 Localization of ENG 1 63 0.78 18.67 27.28
198 INT14690 Localization of CSF2 2 124 0.80 85.17 27.26
199 INT145426 Positive_regulation of Ros1 1 185 0.56 106.76 27.21
200 INT21900 Gene_expression of Mthfd1 2 150 0.75 69.47 27.03
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