J:Journal of Neurogastroenterology and Motility

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT342993 PHEX Regulation of Protein_catabolism of SFTPA1 1 2 0.00 2.84 1.58
2 INT342979 HCL1 Positive_regulation of TRPV1 Positive_regulation of Localization of SFTPA1 1 2 0.00 0.54 1.31
3 INT342990 TRPV1 Positive_regulation of Gene_expression of SFTPA1 1 2 0.06 1.44 1.26
4 INT342988 HCL1 Positive_regulation of TRPV1 1 3 0.04 1.15 1.21
5 INT342986 PTAFR Positive_regulation of Gene_expression of IL6 1 1 0.14 0.39 0.84
6 INT342982 HCL1 Positive_regulation of SFTPA1 1 1 0.00 0.71 0.84
7 INT342991 HCL1 Positive_regulation of CALCA 1 1 0.03 0.71 0.84
8 INT342999 IL6 Positive_regulation of Gene_expression of HIST2H2AA3 1 1 0.00 0.4 0.83
9 INT342992 Negative_regulation of PTAFR Negative_regulation of Gene_expression of HIST2H2AA3 1 1 0.01 0.4 0.78
10 INT313778 Gene_expression of Crhq1 Negative_regulation of Localization of Crh 1 1 0.05 0.66 0.71
11 INT342989 IL8 Regulation of SFTPA1 1 1 0.02 0.38 0.6
12 INT342981 PTAFR Regulation of SFTPA1 1 1 0.03 0.38 0.6
13 INT342980 TRPV1 Negative_regulation of HCL1 Positive_regulation of PTAFR 1 1 0.03 0.07 0.48
14 INT342983 HCL1 Positive_regulation of PTAFR 1 1 0.03 0.07 0.47
15 INT342987 TRPV1 Positive_regulation of Localization of PTAFR 1 1 0.33 0.84 0.43
16 INT342998 DUOX1 Positive_regulation of ROS1 1 1 0.23 0.25 0.43
17 INT342985 IL8 Positive_regulation of PPBP 1 1 0.02 0.66 0.3
18 INT342997 PTAFR Positive_regulation of Gene_expression of HIST2H2AA3 1 1 0.01 0.61 0.24
19 INT342994 IL1B Positive_regulation of Gene_expression of PTAFR 1 1 0.09 0.39 0.22
20 INT343027 Binding of CYP3A4 and Azi1 1 1 0.02 0.75 0.14

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 15 3083 0.78 894.43 1639.02
2 INT6483 Gene_expression of TNF 3 3152 0.78 2515.62 929.82
3 INT5202 Positive_regulation of Gene_expression of Fos 1 1163 0.70 319.28 684
4 INT5228 Positive_regulation of Fos 1 934 0.70 209.8 503.87
5 INT9238 Gene_expression of IL6 3 1575 0.78 1135.66 424.22
6 INT6056 Negative_regulation of Gene_expression of Fos 4 601 0.59 193.05 386.84
7 INT18357 Gene_expression of TRPV1 5 825 0.78 307.11 382.81
8 INT5059 Positive_regulation of TNF 1 1050 0.70 896.51 322.81
9 INT9158 Gene_expression of Tnf 1 722 0.78 522.01 277.68
10 INT9381 Positive_regulation of TRPV1 11 523 0.70 187.4 276.05
11 INT6852 Localization of TNF 1 883 0.81 705.95 270.84
12 INT10832 Gene_expression of IL8 7 1050 0.78 698.72 270
13 INT5972 Gene_expression of IL1B 1 948 0.78 510.91 263.97
14 INT87687 Positive_regulation of Trpv1 1 409 0.70 210.24 257.59
15 INT1562 Localization of Crh 4 499 0.81 126.74 236.68
16 INT626 Localization of CALCA 5 289 0.81 125.39 221.15
17 INT6482 Positive_regulation of Gene_expression of TNF 3 659 0.70 569.88 210
18 INT438 Gene_expression of Crh 4 376 0.78 159.11 169.17
19 INT2867 Gene_expression of CALCA 9 247 0.78 78.78 138.47
20 INT12339 Localization of IL8 3 437 0.81 251.87 117.39
21 INT170025 Gene_expression of Fig4 1 588 0.67 183.27 113.32
22 INT11051 Positive_regulation of Gene_expression of IL6 1 415 0.69 319.21 109.3
23 INT60526 Gene_expression of IL10 1 449 0.78 292.71 107.84
24 INT12082 Localization of IL6 2 365 0.81 241.78 105.78
25 INT69440 Gene_expression of ROS1 2 752 0.78 477.64 103.83
26 INT90091 Gene_expression of GOPC 6 967 0.67 366.22 103.6
27 INT10838 Positive_regulation of IL8 4 381 0.70 295.51 101.62
28 INT82878 Gene_expression of Ccl2 1 201 0.78 164.95 101.35
29 INT4860 Positive_regulation of CALCA 2 148 0.00 73.35 97.61
30 INT69764 Positive_regulation of Cnr1 4 126 0.70 67.8 91.49
31 INT74376 Gene_expression of Cnr1 20 173 0.78 73.43 89.7
32 INT48244 Gene_expression of Il4 1 172 0.76 132.38 73.42
33 INT10837 Positive_regulation of Gene_expression of IL8 2 294 0.70 190.08 70.34
34 INT6849 Localization of IL1B 3 229 0.81 112.56 69.63
35 INT19511 Localization of Il6 1 212 0.81 118.17 67.67
36 INT9489 Gene_expression of SFTPA1 13 112 0.66 55.38 66.45
37 INT83602 Positive_regulation of Gene_expression of TRPV1 3 114 0.70 51.19 56.35
38 INT4241 Regulation of CALCA 1 87 0.62 28.19 55.29
39 INT50405 Negative_regulation of CYP3A4 1 238 0.59 53.65 51.51
40 INT8490 Negative_regulation of CALCA 1 87 0.59 29.73 51.34
41 INT12345 Gene_expression of Il2 1 142 0.78 59.17 51.21
42 INT6473 Positive_regulation of Gene_expression of IL1B 1 204 0.70 117.23 50.86
43 INT4345 Gene_expression of Gtf3a 1 157 0.67 80.75 48.47
44 INT2463 Localization of CCK 4 101 0.81 37.54 47.59
45 INT30170 Gene_expression of Car2 2 330 0.66 77.26 46.76
46 INT2406 Gene_expression of CCK 1 85 0.78 28.04 46.67
47 INT9383 Localization of TRPV1 2 98 0.81 33.23 46.24
48 INT16364 Gene_expression of HLA-DRA 1 234 0.78 118.81 45.01
49 INT17561 Localization of Car2 1 303 0.79 60.95 44.52
50 INT935 Localization of Gtf3a 2 124 0.70 35.72 43.3
51 INT11406 Positive_regulation of Localization of CALCA 2 49 0.70 20.64 42.8
52 INT5502 Positive_regulation of Gene_expression of Crh 7 69 0.70 43.06 42.23
53 INT89 Positive_regulation of Gast 1 187 0.70 80.49 42.07
54 INT30 Gene_expression of Gast 4 158 0.78 99 41.45
55 INT8835 Localization of SFTPA1 8 65 0.68 32.81 38.65
56 INT65889 Gene_expression of RETNLB 4 73 0.34 60.98 38.3
57 INT48222 Positive_regulation of Localization of IL8 1 123 0.59 78.04 37.2
58 INT74563 Positive_regulation of Gene_expression of ROS1 1 258 0.61 168.18 34.08
59 INT50308 Binding of Cnr1 4 61 0.48 14.41 33.52
60 INT2884 Positive_regulation of CCK 3 66 0.69 25.25 30.6
61 INT77652 Negative_regulation of Gene_expression of IL8 1 99 0.59 67.57 30.21
62 INT50230 Positive_regulation of Localization of IL6 1 105 0.70 69.21 29.52
63 INT23463 Positive_regulation of Gene_expression of CALCA 6 47 0.70 18.14 28.76
64 INT15610 Localization of GOPC 2 223 0.65 68.26 28.7
65 INT10506 Gene_expression of PTAFR 18 86 0.76 37.57 28.58
66 INT82882 Localization of Ccl2 1 61 0.80 41.96 28
67 INT52722 Localization of RETNLB 1 54 0.38 48.63 27.98
68 INT75418 Negative_regulation of Cnr1 2 41 0.59 14.65 27.28
69 INT2408 Regulation of CCK 3 37 0.61 10.01 26.66
70 INT95481 Regulation of Gene_expression of TRPV1 1 48 0.62 29.3 26.28
71 INT14884 Positive_regulation of Gene_expression of SFTPA1 12 32 0.25 20.37 26.09
72 INT70048 Positive_regulation of Gene_expression of IL10 1 90 0.55 71.34 25.66
73 INT74377 Regulation of Cnr1 1 38 0.59 16.93 24.77
74 INT10836 Negative_regulation of IL8 1 95 0.59 52.59 24.71
75 INT9377 Positive_regulation of Positive_regulation of TRPV1 2 43 0.70 15.81 24.47
76 INT8836 Positive_regulation of SFTPA1 4 36 0.47 28.37 23.59
77 INT17962 Regulation of Car2 3 124 0.41 33.98 22.71
78 INT2386 Gene_expression of Pgr 1 112 0.78 45.46 22.19
79 INT5503 Negative_regulation of Gene_expression of Crh 1 38 0.59 16.82 21.34
80 INT5586 Binding of Fos 1 47 0.48 12.7 21.33
81 INT52106 Negative_regulation of Localization of IL8 1 57 0.52 22.81 20.8
82 INT18311 Positive_regulation of CD8A 1 145 0.69 113.48 19.44
83 INT77902 Negative_regulation of Positive_regulation of TRPV1 1 30 0.59 9.36 19.2
84 INT5160 Localization of PTAFR 10 61 0.80 42.6 19.16
85 INT70614 Gene_expression of FAS 1 118 0.75 112.33 19.01
86 INT10833 Regulation of Gene_expression of IL8 1 68 0.62 38.74 18.46
87 INT87861 Gene_expression of Il18 1 33 0.78 30.44 18.42
88 INT28642 Gene_expression of CXCR2 2 60 0.78 38.69 18.11
89 INT19948 Gene_expression of Sds 2 34 0.63 14.69 15.44
90 INT75434 Gene_expression of Il13 1 27 0.52 26.19 15.4
91 INT61893 Gene_expression of Ghrl 3 125 0.75 71.49 15.14
92 INT25266 Positive_regulation of Localization of IL1B 2 38 0.69 15.89 14.35
93 INT47909 Binding of CPP 1 32 0.48 24.9 13.79
94 INT74375 Positive_regulation of Gene_expression of Cnr1 7 24 0.70 14.25 13.66
95 INT11071 Positive_regulation of PPBP 1 43 0.68 26.85 13.43
96 INT97237 Transcription of TRPV1 2 33 0.72 10.56 12.4
97 INT3969 Positive_regulation of Sds 1 27 0.69 7.52 12.31
98 INT1139 Gene_expression of IgG-2a 1 35 0.65 19.19 12
99 INT170601 Positive_regulation of Gene_expression of GOPC 2 122 0.43 42.79 11.68
100 INT14513 Localization of Ghrl 1 52 0.78 29.26 11.63
101 INT5045 Regulation of VIP 1 26 0.62 7.15 11.61
102 INT13303 Positive_regulation of PTAFR 6 40 0.69 16.27 11.56
103 INT66606 Gene_expression of CXCR1 2 34 0.75 27.79 11.36
104 INT67401 Gene_expression of Il12a 1 25 0.55 20.04 11.12
105 INT15804 Gene_expression of ISG20 1 83 0.75 44.33 10.58
106 INT108917 Positive_regulation of CRX 2 23 0.50 21.32 10.5
107 INT10019 Binding of CD8A 1 57 0.36 31.49 10.08
108 INT123142 Gene_expression of DEFB4A 2 54 0.76 36.14 10.02
109 INT106565 Negative_regulation of Gene_expression of Cnr1 1 19 0.59 6.98 9.93
110 INT157941 Gene_expression of IL-17 1 65 0.65 20.39 9.89
111 INT29988 Gene_expression of Mecp2 1 27 0.78 5.45 9.47
112 INT51837 Negative_regulation of TACR1 2 17 0.43 6.5 9.12
113 INT2885 Positive_regulation of Localization of CCK 1 19 0.70 9.92 8.94
114 INT22481 Gene_expression of CADM1 1 28 0.65 30.26 8.5
115 INT30526 Negative_regulation of PTAFR 3 15 0.58 8.15 8.19
116 INT88868 Binding of MCS 1 45 0.40 37.43 7.98
117 INT87976 Regulation of Gene_expression of Cnr1 5 9 0.58 6.87 7.51
118 INT14599 Localization of Tpsab1 1 36 0.79 14.58 7.18
119 INT53240 Positive_regulation of Localization of SFTPA1 5 11 0.11 7.99 7.15
120 INT10228 Positive_regulation of PCS 1 49 0.67 28.72 7
121 INT10507 Positive_regulation of Gene_expression of PTAFR 7 15 0.61 10.24 6.61
122 INT12239 Regulation of Localization of CCK 1 11 0.62 6.03 6.61
123 INT51269 Gene_expression of HIST2H2AA3 11 16 0.56 10.16 6.55
124 INT48234 Negative_regulation of Gene_expression of PTAFR 3 11 0.57 3.97 6.25
125 INT115594 Gene_expression of Cd80 2 9 0.67 7.8 5.92
126 INT116490 Positive_regulation of Localization of TRPV1 1 9 0.68 3.86 5.67
127 INT75833 Negative_regulation of Positive_regulation of IL8 1 15 0.53 6.69 5.59
128 INT62510 Positive_regulation of MCS 1 32 0.60 11.79 5.45
129 INT92447 Negative_regulation of Gene_expression of SFTPA1 2 6 0.35 2.81 5.43
130 INT24886 Negative_regulation of SFTPA1 2 11 0.12 4.35 5.03
131 INT117855 Negative_regulation of Ghrl 1 29 0.57 17.52 5
132 INT37148 Negative_regulation of Gene_expression of CALCA 1 7 0.43 1.91 4.98
133 INT10896 Regulation of PTAFR 2 16 0.61 4.22 4.5
134 INT158100 Positive_regulation of Gene_expression of Cd80 3 4 0.42 4.95 4.5
135 INT88947 Positive_regulation of Gene_expression of Pgr 1 22 0.64 7 4.39
136 INT76467 Regulation of Gene_expression of Car2 2 41 0.37 12.88 4.21
137 INT87974 Transcription of Cnr1 1 15 0.65 2.51 4.02
138 INT157664 Positive_regulation of DEFB4A 1 15 0.56 10.87 3.8
139 INT133641 Binding of CCL28 3 5 0.47 3.23 3.71
140 INT13302 Binding of PTAFR 2 20 0.48 7.03 3.7
141 INT117117 Positive_regulation of REM1 3 12 0.40 10.1 3.33
142 INT114412 Localization of HCL1 3 18 0.56 3.69 2.96
143 INT323365 Positive_regulation of Gene_expression of HIST2H2AA3 5 6 0.01 3.04 2.96
144 INT28640 Positive_regulation of Gene_expression of CXCR2 1 8 0.69 5.51 2.91
145 INT72126 Positive_regulation of HIST2H2AA3 4 16 0.38 3.94 2.89
146 INT60672 Regulation of Gene_expression of CALCA 1 3 0.61 1.76 2.85
147 INT78327 Positive_regulation of Positive_regulation of CCK 1 3 0.47 1.74 2.82
148 INT49808 Localization of tryptase 1 11 0.78 8.74 2.67
149 INT115593 Gene_expression of Cd86 2 15 0.57 6.55 2.62
150 INT169987 Transcription of GOPC 1 45 0.60 21.88 2.61
151 INT337317 Positive_regulation of Localization of PTAFR 5 2 0.51 3.88 2.5
152 INT130961 Gene_expression of MADCAM1 3 4 0.33 5.03 2.28
153 INT22605 Regulation of Pgr 1 22 0.62 7.1 2.26
154 INT18654 Gene_expression of HRH2 3 9 0.67 5.73 2.19
155 INT55469 Positive_regulation of Positive_regulation of PTAFR 1 9 0.47 3 2.17
156 INT91519 Negative_regulation of Positive_regulation of PTAFR 2 4 0.41 1.52 2.15
157 INT20098 Positive_regulation of PGC 1 11 0.64 4.78 2.07
158 INT99572 Localization of Kit 1 13 0.75 5.23 1.95
159 INT248374 Binding of IKBKAP 1 10 0.42 10.45 1.9
160 INT144541 Negative_regulation of Gene_expression of Mecp2 1 3 0.42 1.43 1.9
161 INT265010 Negative_regulation of Gene_expression of Sds 1 4 0.20 1.07 1.69
162 INT342978 Positive_regulation of Gene_expression of Cd86 3 1 0.25 2.05 1.65
163 INT323984 Regulation of Trpm7 1 2 0.61 0.66 1.64
164 INT79775 Binding of HCL1 1 2 0.03 0.98 1.59
165 INT37204 Gene_expression of HCL1 1 4 0.65 0.76 1.54
166 INT94189 Positive_regulation of FUT3 1 11 0.31 6.61 1.5
167 INT70566 Protein_catabolism of SFTPA1 1 3 0.20 3.31 1.47
168 INT83891 Gene_expression of FUT3 1 20 0.61 10.49 1.41
169 INT107075 Gene_expression of Cd69 1 10 0.62 5.33 1.41
170 INT311964 Positive_regulation of Cd80 2 2 0.30 1.96 1.32
171 INT16013 Gene_expression of Rac1 1 52 0.75 23.79 1.21
172 INT343012 Positive_regulation of HCL1 2 1 0.04 0.33 1.13
173 INT323983 Regulation of Trpc4 1 1 0.33 0 1.12
174 INT101950 Gene_expression of Crhq1 1 3 0.68 1.26 1.1
175 INT163409 Negative_regulation of Positive_regulation of CRX 1 2 0.03 1.85 0.99
176 INT92291 Localization of CXCR1 1 4 0.73 3.06 0.98
177 INT288483 Gene_expression of Tlr3 1 8 0.72 4.51 0.97
178 INT277920 Binding of MADCAM1 1 4 0.14 3.11 0.96
179 INT127440 Positive_regulation of Negative_regulation of Cnr1 1 2 0.50 1.57 0.94
180 INT28641 Regulation of Gene_expression of CXCR2 1 1 0.45 1.9 0.91
181 INT246311 Protein_catabolism of Snap25 1 6 0.66 1.15 0.89
182 INT313773 Negative_regulation of Binding of CCL28 1 1 0.39 1.05 0.86
183 INT288484 Gene_expression of Tlr8 1 5 0.44 4.19 0.83
184 INT323980 Regulation of Localization of Ghrl 1 5 0.60 3.04 0.8
185 INT343009 Negative_regulation of Protein_catabolism of SFTPA1 1 1 0.05 1.42 0.79
186 INT342976 Negative_regulation of Gene_expression of Cxcl9 1 1 0.26 0.41 0.77
187 INT288495 Gene_expression of Tlr7 1 3 0.50 2.83 0.76
188 INT154350 Localization of Cxcl9 1 2 0.19 0.41 0.76
189 INT288486 Negative_regulation of Gene_expression of Tlr8 1 2 0.29 1.76 0.76
190 INT323979 Negative_regulation of Negative_regulation of Ghrl 1 2 0.42 0.98 0.76
191 INT342974 Gene_expression of Cxcl9 1 1 0.36 0.41 0.76
192 INT249049 Positive_regulation of ARID1B 1 14 0.56 24.77 0.71
193 INT179863 Binding of HIST2H2AA3 2 2 0.00 1.71 0.68
194 INT292258 Negative_regulation of Positive_regulation of SFTPA1 1 2 0.05 0.83 0.65
195 INT163366 Transcription of Foxp3 1 2 0.35 0.72 0.53
196 INT342975 Positive_regulation of Positive_regulation of Cd80 1 1 0.30 0.61 0.5
197 INT342977 Positive_regulation of Cd86 1 1 0.11 0.61 0.5
198 INT40911 Negative_regulation of Gene_expression of HRH2 1 3 0.43 1.71 0.48
199 INT199409 Positive_regulation of Negative_regulation of CYP3A4 1 7 0.50 2.54 0.41
200 INT133819 Localization of CXCR2 1 3 0.61 1.64 0.37
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