J:Journal of Osteoporosis

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT352547 Binding of CFTR and DMD 1 1 0.01 1.42 0.35
2 INT335888 Lrp5 Negative_regulation of Gene_expression of Tph1 1 1 0.22 0.15 0.21
3 INT352555 DKK1 Positive_regulation of Wnt2 1 1 0.01 0.25 0.1
4 INT335890 Binding of Dkk1 and Lrp4 1 1 0.37 0.64 0.07
5 INT335886 Binding of Sost and Lrp4 1 1 0.28 0.65 0.07
6 INT269759 PTH Positive_regulation of DMD 2 1 0.06 0.37 0.03
7 INT254433 Binding of Lrp5 and Sost 2 2 0.39 1.51 0.03
8 INT335884 Akt1 Regulation of Positive_regulation of Wnt5a 1 1 0.03 0.15 0
9 INT335887 Akt1 Regulation of Lrp6 1 1 0.06 0.15 0
10 INT335883 Binding of Lrp6 and Wnt5a 1 1 0.27 0.08 0
11 INT335891 Binding of Dkk1 and Lrp5 1 1 0.39 0.57 0
12 INT335882 Dkk1 Negative_regulation of Wnt2 1 1 0.02 0.15 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5374 Gene_expression of Esr1 1 412 0.77 263.89 67.34
2 INT251 Regulation of INS 1 398 0.62 232.47 55.04
3 INT60710 Gene_expression of Col7a1 1 217 0.78 113.2 35.2
4 INT124371 Negative_regulation of Gsk3b 3 170 0.55 87.92 15.51
5 INT16167 Negative_regulation of DMD 6 186 0.57 108.71 15.25
6 INT16166 Positive_regulation of DMD 8 348 0.67 133.22 15.06
7 INT129883 Gene_expression of Dkk1 6 56 0.77 45.42 12.52
8 INT744 Positive_regulation of PTH 1 130 0.70 95.02 11.7
9 INT6516 Positive_regulation of BGLAP 2 45 0.67 26.61 9.9
10 INT123701 Negative_regulation of VDR 2 61 0.59 48.94 9.67
11 INT135372 Positive_regulation of Gsk3b 1 72 0.70 50.03 9.28
12 INT17701 Gene_expression of PTHLH 1 103 0.78 64.23 8.85
13 INT123459 Gene_expression of Tnfrsf11b 3 35 0.58 24.16 7.26
14 INT138802 Gene_expression of CFTR 4 36 0.70 18.8 7.02
15 INT6512 Gene_expression of PTH 3 103 0.77 76.29 6.33
16 INT13396 Gene_expression of DMD 1 125 0.75 57.81 5.45
17 INT87022 Gene_expression of Apc 1 68 0.67 46.98 5.22
18 INT151102 Positive_regulation of CFTR 1 22 0.61 15.27 5.12
19 INT124375 Gene_expression of Wnt2 2 67 0.56 38.03 4.67
20 INT169756 Binding of CFTR 2 9 0.35 9.65 4.55
21 INT111156 Negative_regulation of Dkk1 4 21 0.58 20.08 4.27
22 INT167284 Phosphorylation of Gsk3b 1 88 0.82 36.03 4.21
23 INT113282 Negative_regulation of TNFRSF11B 1 17 0.57 13.71 4.17
24 INT126659 Gene_expression of Tph1 1 22 0.78 2.04 4.04
25 INT151099 Negative_regulation of CFTR 5 12 0.59 10.28 3.79
26 INT16165 Regulation of DMD 3 114 0.60 35.13 3.64
27 INT171998 Binding of DMD 1 58 0.47 38.13 3.35
28 INT28094 Binding of PTH 1 29 0.37 13.57 3.09
29 INT188047 Positive_regulation of Wnt2 4 51 0.58 31.41 2.94
30 INT15606 Localization of FSHB 1 24 0.78 9.16 2.49
31 INT211970 Negative_regulation of Best1 4 49 0.14 37.33 2.32
32 INT2544 Localization of PTH 1 39 0.81 30.55 2.22
33 INT146660 Negative_regulation of Ctsk 2 9 0.43 6.01 2.07
34 INT198885 Gene_expression of Lrp1 1 33 0.57 10.2 1.91
35 INT139475 Negative_regulation of DKK1 1 14 0.52 9.2 1.76
36 INT112270 Negative_regulation of Cntnap1 1 4 0.57 1.74 1.76
37 INT227759 Gene_expression of Best1 2 26 0.42 20.36 1.73
38 INT38266 Localization of PTPRC 1 30 0.68 17.05 1.68
39 INT182643 Binding of TNFSF11 1 15 0.35 13.12 1.61
40 INT224424 Regulation of TNFRSF11B 1 12 0.61 6.29 1.61
41 INT211969 Positive_regulation of Best1 1 34 0.11 14.92 1.44
42 INT6514 Positive_regulation of Gene_expression of PTH 1 28 0.67 30.28 1.37
43 INT242153 Negative_regulation of Wnt2 4 19 0.49 11.87 1.37
44 INT108519 Binding of Lrp6 5 8 0.44 1.47 1.19
45 INT208536 Positive_regulation of Positive_regulation of Gsk3b 1 6 0.30 4.83 1.11
46 INT23495 Positive_regulation of Localization of FSHB 1 7 0.40 0.4 1.07
47 INT168397 Gene_expression of Cyp19a1 1 2 0.06 1.77 1.06
48 INT165338 Binding of Dkk1 2 4 0.37 3.64 1.04
49 INT124374 Binding of Wnt2 4 21 0.31 10.16 0.99
50 INT192686 Positive_regulation of Positive_regulation of DMD 1 8 0.41 4.66 0.93
51 INT198872 Binding of Lrp1 1 9 0.36 2.73 0.89
52 INT62155 Positive_regulation of Gene_expression of DMD 1 17 0.67 6.17 0.82
53 INT211972 Regulation of Best1 1 18 0.33 12.04 0.67
54 INT335876 Negative_regulation of Sost 18 11 0.51 6.77 0.67
55 INT242137 Negative_regulation of Positive_regulation of Gsk3b 1 7 0.39 2.99 0.67
56 INT182010 Regulation of Tnfrsf11b 2 2 0.18 1.13 0.67
57 INT245721 Localization of FRZB 1 6 0.78 4.3 0.6
58 INT202225 Regulation of Fembrs1 2 3 0.10 1.3 0.57
59 INT213503 Regulation of Wnt2 2 9 0.37 3.54 0.56
60 INT201524 Localization of Wnt2 2 14 0.62 9.24 0.46
61 INT188050 Regulation of Gene_expression of Wnt2 1 9 0.37 3.13 0.44
62 INT46615 Negative_regulation of Gene_expression of PTH 1 8 0.57 5.1 0.4
63 INT110258 Negative_regulation of PTHLH 1 6 0.56 5.42 0.39
64 INT211968 Localization of Best1 3 11 0.40 9.33 0.38
65 INT277463 Localization of Sfrp1 1 2 0.23 0.64 0.36
66 INT302314 Negative_regulation of SOST 1 5 0.44 2.22 0.33
67 INT338125 Gene_expression of GET4 5 1 0.29 2.74 0.32
68 INT237621 Gene_expression of Cntnap1 4 2 0.75 1.06 0.31
69 INT297804 Regulation of Lrp5 4 6 0.60 2.31 0.27
70 INT258314 Positive_regulation of Cntnap1 1 3 0.32 0.92 0.27
71 INT335875 Regulation of Lrp6 3 1 0.57 0.43 0.27
72 INT254427 Binding of Lrp5 8 10 0.48 5.43 0.26
73 INT335874 Regulation of Lrp4 1 1 0.18 0 0.23
74 INT335878 Localization of Sost 3 3 0.69 1.11 0.22
75 INT312604 Gene_expression of Lrp4 2 2 0.71 1.48 0.21
76 INT335879 Negative_regulation of Gene_expression of Tph1 1 1 0.19 0.15 0.21
77 INT335864 Gene_expression of Sost 6 4 0.77 2.36 0.2
78 INT338126 Transcription of GET4 1 1 0.30 0.22 0.2
79 INT352553 Negative_regulation of Binding of Wnt2 2 1 0.03 0.49 0.2
80 INT335869 Binding of Sost 6 6 0.32 1.79 0.18
81 INT254429 Negative_regulation of Lrp5 2 4 0.57 1.95 0.18
82 INT258920 Regulation of CASR 1 3 0.22 2.02 0.18
83 INT335902 Localization of Fembrs1 4 1 0.16 0 0.17
84 INT335861 Localization of Lrp6 1 1 0.69 0.54 0.17
85 INT335897 Regulation of Localization of Fembrs1 4 1 0.10 0 0.17
86 INT338124 Positive_regulation of GET4 1 1 0.22 0.17 0.15
87 INT70854 Regulation of Localization of PTH 1 2 0.27 1.13 0.14
88 INT70262 Gene_expression of Pth 1 8 0.66 5.64 0.12
89 INT254428 Binding of Lrp4 2 4 0.44 1.52 0.11
90 INT338141 Localization of BAZ1A 1 2 0.73 0.35 0.1
91 INT335899 Transcription of Fembrs1 2 1 0.15 0 0.09
92 INT335900 Regulation of Transcription of Fembrs1 2 1 0.10 0 0.09
93 INT302313 Gene_expression of SOST 2 6 0.67 2.06 0.08
94 INT302317 Positive_regulation of Gene_expression of SOST 2 4 0.60 1.58 0.08
95 INT162576 Positive_regulation of Wnt5a 1 3 0.48 0.71 0.08
96 INT146805 Positive_regulation of Gene_expression of Pth 1 4 0.49 4.2 0.07
97 INT254426 Gene_expression of Lrp5 1 5 0.67 3.28 0.06
98 INT335871 Negative_regulation of Sfrp2 2 1 0.18 0.91 0.06
99 INT335860 Negative_regulation of Sfrp1 2 1 0.18 0.91 0.06
100 INT201777 Phosphorylation of Wnt2 1 2 0.03 1.31 0.05
101 INT335865 Positive_regulation of Phosphorylation of Lrp6 3 1 0.64 0.46 0.05
102 INT335862 Phosphorylation of Lrp6 2 1 0.76 0.37 0.05
103 INT335868 Negative_regulation of Gene_expression of Sost 3 2 0.58 1.12 0.04
104 INT302318 Regulation of SOST 1 2 0.34 0.46 0.04
105 INT352546 Positive_regulation of Negative_regulation of Ctsk 1 1 0.09 0.37 0.04
106 INT352551 Positive_regulation of Binding of PTH 1 1 0.17 0.27 0.04
107 INT335867 Positive_regulation of Negative_regulation of Sfrp2 1 1 0.14 0.49 0.03
108 INT335859 Regulation of Sfrp1 1 1 0.08 0.43 0.03
109 INT198907 Positive_regulation of Gene_expression of Lrp1 1 7 0.49 3.2 0
110 INT227758 Positive_regulation of Localization of Best1 1 3 0.07 1.95 0
111 INT297757 Transcription of Lrp5 1 2 0.68 0.82 0
112 INT273823 Gene_expression of Gen1 4 2 0.10 0.92 0
113 INT338138 Gene_expression of BAZ1A 1 2 0.65 0.57 0
114 INT297820 Regulation of Transcription of Lrp5 1 2 0.44 0.83 0
115 INT338123 Phosphorylation of GET4 1 1 0.35 0.22 0
116 INT338152 Positive_regulation of Gene_expression of Sost 1 1 0.69 0.2 0
117 INT335872 Positive_regulation of Gene_expression of Lrp6 2 1 0.46 0.18 0
118 INT335880 Regulation of Wnt5a 1 1 0.32 0.07 0
119 INT335901 Regulation of Cntnap1 1 1 0.17 0.31 0
120 INT335896 Binding of Fembrs1 4 1 0.08 0 0
121 INT335870 Regulation of Gene_expression of Tnfrsf11b 1 1 0.13 0.11 0
122 INT338142 Negative_regulation of BAZ1A 1 1 0.16 0.37 0
123 INT335903 Regulation of Gene_expression of Gen1 1 1 0.07 0.14 0
124 INT338139 Positive_regulation of BAZ1A 1 1 0.19 0.27 0
125 INT335898 Binding of Gen1 1 1 0.06 0.38 0
126 INT338151 Regulation of Sost 1 1 0.39 0.16 0
127 INT335866 Regulation of Transcription of Lrp6 1 1 0.42 0.25 0
128 INT335904 Positive_regulation of Gen1 1 1 0.08 0.2 0
129 INT335854 Negative_regulation of Localization of Best1 1 1 0.06 0.33 0
130 INT335881 Gene_expression of Lrp6 1 1 0.62 0.09 0
131 INT338140 Positive_regulation of Localization of BAZ1A 1 1 0.19 0.35 0
132 INT335873 Transcription of Lrp6 1 1 0.64 0.25 0
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