J:Journal of pain research

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT351281 AP1M2 Regulation of NCOR2 1 1 0.00 0.85 1.9
2 INT351246 Binding of OPN1LW and NNT 1 1 0.03 0.53 1.45
3 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 1 0.08 0.65 1.35
4 INT351245 Binding of TNC and OPN1LW 1 1 0.03 0.89 1.31
5 INT351311 Has1 Regulation of Gene_expression of MMP3 1 1 0.11 1.15 0.95
6 INT351323 Nts Regulation of Localization of Calca 1 1 0.01 0.6 0.85
7 INT351322 Nts Regulation of Localization of Napa 1 1 0.01 0.56 0.77
8 INT351276 CYP2D6 Regulation of CYP1A2 1 1 0.12 0 0.63
9 INT351237 HRAS Regulation of CBL 1 1 0.00 0.48 0.4
10 INT351318 Binding of CYP2C19 and Cyp1a2 1 1 0.01 0.28 0.22

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 1 2008 0.81 518.3 1408.65
2 INT158 Localization of Prl 1 2431 0.81 378.96 952.2
3 INT6483 Gene_expression of TNF 1 3152 0.78 2515.62 929.82
4 INT76660 Gene_expression of Trpv1 2 691 0.78 329.46 386.42
5 INT18357 Gene_expression of TRPV1 1 825 0.78 307.11 382.81
6 INT5979 Gene_expression of Oprd1 1 428 0.78 75.64 320.32
7 INT4941 Positive_regulation of Oprd1 1 345 0.70 74.26 304.41
8 INT11624 Gene_expression of OPRM1 2 445 0.78 72.36 294.36
9 INT49750 Negative_regulation of CPOX 3 735 0.58 360.06 274.19
10 INT68684 Gene_expression of VEGFA 1 2371 0.78 1742.52 259.2
11 INT4759 Negative_regulation of Localization of Calca 1 294 0.59 82.62 226.45
12 INT2391 Negative_regulation of PTGS1 1 501 0.59 207.62 205.6
13 INT50670 Gene_expression of CPOX 5 763 0.76 442.13 195.02
14 INT6354 Localization of Gabrg1 1 321 0.74 41.41 186.74
15 INT4937 Negative_regulation of Oprd1 1 224 0.59 44.51 171.11
16 INT768 Positive_regulation of Oprl1 2 179 0.70 40.05 156.93
17 INT5008 Localization of Calca 2 204 0.81 80.35 125.16
18 INT65731 Gene_expression of Cnr1 1 234 0.78 63.82 109.34
19 INT11587 Gene_expression of CSF2 1 645 0.78 544.38 93.89
20 INT77435 Positive_regulation of Nos2 1 343 0.70 208.49 91.43
21 INT9516 Negative_regulation of Gabrg1 1 149 0.53 27.83 91.02
22 INT1639 Negative_regulation of OPRM1 1 107 0.59 13.86 90.37
23 INT15769 Gene_expression of Il1b 1 146 0.78 114.51 75.35
24 INT98621 Regulation of Trpv1 1 121 0.62 79.24 75.23
25 INT15913 Negative_regulation of CYP2D6 2 174 0.59 22.45 70.91
26 INT8357 Gene_expression of KNG1 1 153 0.75 77.26 68.66
27 INT7134 Localization of KNG1 1 127 0.79 65.73 67.97
28 INT65733 Positive_regulation of Cnr1 2 125 0.70 40.27 67.33
29 INT15613 Negative_regulation of Ptgs2 1 160 0.59 71.08 65.08
30 INT9664 Binding of LBP 12 127 0.48 94.9 63.42
31 INT65730 Gene_expression of Cnr2 2 129 0.78 60.15 63.1
32 INT546 Binding of ALB 1 311 0.48 85.98 60.14
33 INT1456 Regulation of Oprl1 2 61 0.62 19.5 52.87
34 INT69484 Positive_regulation of Gene_expression of OPRM1 2 75 0.70 12.86 52.27
35 INT50334 Negative_regulation of Cnr1 2 84 0.58 30.86 51.75
36 INT16850 Negative_regulation of Localization of Gabrg1 1 73 0.51 8.28 47.89
37 INT5781 Gene_expression of Edn1 7 190 0.78 99.1 46
38 INT98498 Binding of Trpv1 1 75 0.48 33.67 44.4
39 INT29496 Gene_expression of MMP3 1 136 0.75 49.49 41.78
40 INT56870 Gene_expression of CYP2D6 2 87 0.78 8.83 37.53
41 INT9082 Positive_regulation of ESR1 1 238 0.69 148.51 36.69
42 INT66005 Regulation of Cnr1 2 47 0.61 19.21 34.52
43 INT34465 Regulation of Oprd1 1 34 0.45 7.14 34.29
44 INT19759 Gene_expression of LBP 1 77 0.77 56.44 33.23
45 INT234 Binding of Alb 1 151 0.48 52.34 32.97
46 INT169180 Binding of SNRNP70 1 204 0.47 119.1 29.3
47 INT651 Positive_regulation of PTGS1 1 93 0.69 37.27 29.18
48 INT6855 Binding of NCOR2 3 71 0.41 15.64 28.96
49 INT12129 Gene_expression of CYP3A4 1 107 0.78 23.11 27.6
50 INT3167 Binding of KNG1 1 48 0.48 23.26 26.77
51 INT78251 Positive_regulation of LBP 6 38 0.69 39.98 26.73
52 INT3760 Positive_regulation of ALB 1 142 0.70 87.46 26.7
53 INT9088 Negative_regulation of LBP 4 48 0.58 33.06 25.89
54 INT27933 Gene_expression of NCOR2 3 65 0.72 31.35 24.23
55 INT6726 Positive_regulation of Edn1 3 118 0.70 65.96 24.07
56 INT35716 Positive_regulation of NCOR2 2 45 0.60 18 23.54
57 INT1704 Positive_regulation of PCa 1 68 0.59 34.92 23.36
58 INT125190 Regulation of Gene_expression of Trpv1 1 38 0.62 32.57 23.2
59 INT64175 Negative_regulation of Gene_expression of CPOX 3 66 0.38 39.64 23.07
60 INT823 Negative_regulation of ESR1 2 144 0.58 63.72 22.52
61 INT8048 Gene_expression of Nts 1 45 0.74 8.9 21.84
62 INT28216 Gene_expression of HRAS 4 173 0.75 93.97 20.78
63 INT116282 Gene_expression of Mmp13 2 83 0.75 45.4 20.18
64 INT5048 Binding of Edn1 1 55 0.47 18.86 19.16
65 INT101578 Regulation of Cnr2 3 26 0.62 16.7 19.12
66 INT120446 Positive_regulation of Cnr2 1 32 0.70 16.3 18.91
67 INT66004 Binding of Cnr2 1 35 0.48 12.82 18.63
68 INT68347 Negative_regulation of Cyp2d4 5 34 0.58 7.62 18.35
69 INT50404 Negative_regulation of CYP1A2 4 49 0.59 8.61 17.35
70 INT62681 Negative_regulation of LEP 2 93 0.59 66.97 15.77
71 INT32706 Gene_expression of Cyp3a23/3a1 1 51 0.65 19.48 15.06
72 INT90766 Gene_expression of PCS 2 93 0.77 40.48 14.51
73 INT39507 Positive_regulation of TXNRD1 6 37 0.68 12.47 14.25
74 INT5806 Regulation of Edn1 1 63 0.62 23.46 13.88
75 INT6365 Localization of Edn1 4 56 0.81 18.84 13.83
76 INT15044 Localization of Nts 2 30 0.75 4.58 13.72
77 INT20632 Gene_expression of TNC 1 72 0.78 30.43 13.16
78 INT127022 Gene_expression of Lts1 2 43 0.23 28.29 12.64
79 INT5987 Positive_regulation of Positive_regulation of Oprl1 2 11 0.49 2.81 12.57
80 INT50580 Binding of PPIG 1 39 0.36 11.17 12.34
81 INT10798 Positive_regulation of CYP2D6 2 24 0.56 5.82 11.31
82 INT57000 Localization of LBP 2 21 0.78 11.01 10.01
83 INT53290 Gene_expression of OPN1LW 8 5 0.31 6.9 9.15
84 INT35269 Localization of SGCG 1 38 0.78 14.68 9.01
85 INT14301 Binding of CSF2 2 82 0.48 67.95 8.98
86 INT53288 Binding of OPN1LW 6 5 0.11 4.24 8.9
87 INT103251 Negative_regulation of Localization of Calca 1 13 0.43 9.36 8.86
88 INT22798 Regulation of Shbg 1 64 0.60 26.71 8.76
89 INT250978 Binding of FMOD 5 4 0.16 12.32 8.75
90 INT73234 Positive_regulation of Lbp 4 13 0.69 12.55 8.57
91 INT15805 Gene_expression of TFRC 2 35 0.75 17.44 8.52
92 INT7813 Regulation of SRI 1 25 0.61 6.18 8.13
93 INT79166 Regulation of TNC 4 12 0.44 9.42 8.13
94 INT80822 Positive_regulation of MRGPRX1 1 30 0.67 3.66 7.73
95 INT10899 Positive_regulation of Gene_expression of Edn1 3 32 0.70 24.88 7.65
96 INT79168 Binding of TNC 1 39 0.47 16.51 7.55
97 INT49751 Negative_regulation of Positive_regulation of PTGS1 1 12 0.45 4.73 7.23
98 INT16268 Binding of HTR3A 1 15 0.47 7.38 7.18
99 INT168399 Localization of Cnr2 2 12 0.81 4.37 6.77
100 INT69561 Positive_regulation of GSTM1 1 23 0.50 5.69 6.36
101 INT168383 Positive_regulation of Mmp13 1 27 0.67 17.9 6.27
102 INT8683 Positive_regulation of F3 1 31 0.67 42.89 6.21
103 INT134585 Negative_regulation of Cnr2 1 10 0.43 3.98 6.16
104 INT250982 Positive_regulation of FMOD 1 7 0.24 8.65 6.09
105 INT20899 Negative_regulation of GNAI1 1 12 0.57 4.24 6.07
106 INT19916 Gene_expression of GPHA2 3 18 0.48 9.78 6.04
107 INT20331 Positive_regulation of CYP1A2 1 31 0.69 8.6 5.92
108 INT9567 Binding of Nts 1 10 0.44 2.14 5.89
109 INT120335 Gene_expression of SNAP25 3 24 0.65 9.44 5.83
110 INT77955 Negative_regulation of PCS 1 55 0.43 39.32 5.76
111 INT190298 Binding of MRGPRX1 3 61 0.46 2.66 5.75
112 INT68899 Binding of CYP1A2 1 19 0.48 2.33 5.73
113 INT134346 Binding of PCS 1 51 0.37 22.27 5.67
114 INT65135 Binding of CYP2C19 2 17 0.48 1.82 5.2
115 INT230829 Localization of Cyp2d4 2 3 0.63 0.61 5.18
116 INT351278 Regulation of FMOD 5 1 0.09 6.45 5.16
117 INT10138 Negative_regulation of Gene_expression of KNG1 1 13 0.57 9.57 4.9
118 INT55419 Regulation of CYP1A2 1 19 0.62 5.3 4.75
119 INT100772 Negative_regulation of TXNRD1 3 10 0.41 3.47 4.74
120 INT95538 Localization of CYP2D6 1 21 0.81 5.69 4.73
121 INT17103 Negative_regulation of Prep 2 15 0.38 4.95 4.71
122 INT189842 Negative_regulation of Gene_expression of Cnr2 1 8 0.59 4.21 4.67
123 INT14831 Negative_regulation of TNC 1 18 0.50 8.71 4.61
124 INT49652 Gene_expression of Fabp4 4 7 0.67 6.23 4.61
125 INT140199 Positive_regulation of Gene_expression of Cyp3a23/3a1 1 9 0.45 4.91 4.56
126 INT250981 Gene_expression of FMOD 4 2 0.20 7.3 4.47
127 INT47044 Positive_regulation of ORM1 1 5 0.68 0.58 4.46
128 INT35765 Gene_expression of TXNRD1 1 47 0.56 9.16 4.43
129 INT20981 Binding of HRAS 1 42 0.48 24.49 4.23
130 INT180338 Binding of Cyp2d4 2 12 0.47 6.87 4.09
131 INT33951 Regulation of TXNRD1 1 18 0.51 6.97 4.02
132 INT80175 Positive_regulation of Gene_expression of HRAS 2 24 0.67 14.69 3.97
133 INT169475 Localization of HRAS 1 14 0.73 9.02 3.9
134 INT3127 Gene_expression of SRI 1 38 0.68 26.29 3.82
135 INT351271 Binding of Fabp4 4 1 0.48 3.92 3.79
136 INT85843 Negative_regulation of BPI 1 5 0.35 5.13 3.77
137 INT106618 Positive_regulation of CIB1 1 9 0.63 3.38 3.63
138 INT18282 Binding of SRI 2 10 0.36 3.31 3.59
139 INT119420 Phosphorylation of MAP2K6 1 8 0.79 4.89 3.52
140 INT11107 Binding of Lbp 2 12 0.42 4.42 3.41
141 INT15801 Positive_regulation of TFRC 2 11 0.33 6.35 3.3
142 INT179489 Positive_regulation of Fabp4 3 3 0.60 3.62 3.15
143 INT41727 Negative_regulation of Localization of Nts 1 3 0.39 1.48 3.15
144 INT261712 Regulation of GABRB3 1 6 0.09 3.03 3.14
145 INT258081 Protein_catabolism of ABAT 1 5 0.10 2.57 2.86
146 INT21533 Positive_regulation of Il1f5 1 7 0.25 4.78 2.77
147 INT90960 Positive_regulation of Gene_expression of CYP2D6 1 9 0.50 2.06 2.76
148 INT24904 Negative_regulation of PAPPA 1 13 0.57 9.93 2.74
149 INT87822 Binding of Cyp1a2 1 8 0.47 0.84 2.72
150 INT155216 Negative_regulation of Gene_expression of CYP3A4 1 9 0.56 3.81 2.71
151 INT130672 Binding of Ugt2b7 1 2 0.22 0.38 2.71
152 INT351263 Binding of CLOCK 3 1 0.18 0.46 2.71
153 INT203154 Positive_regulation of Gene_expression of Lts1 1 6 0.17 3.68 2.67
154 INT62683 Negative_regulation of HRAS 1 19 0.57 7.93 2.65
155 INT185407 Binding of PER1 1 13 0.42 9.32 2.6
156 INT29228 Negative_regulation of Binding of NCOR2 1 4 0.02 0.62 2.47
157 INT109559 Localization of Napa 1 16 0.61 1.3 2.42
158 INT180343 Negative_regulation of Negative_regulation of Cyp2d4 2 2 0.36 0.49 2.38
159 INT250980 Negative_regulation of FMOD 1 2 0.14 2.67 2.31
160 INT351277 Positive_regulation of Gene_expression of FMOD 3 1 0.10 5.79 2.25
161 INT83236 Localization of PGR 1 14 0.73 8.26 2.23
162 INT250983 Regulation of Gene_expression of FMOD 1 2 0.09 2.62 2.18
163 INT20332 Positive_regulation of Positive_regulation of CYP1A2 1 4 0.69 0.68 2.17
164 INT118918 Negative_regulation of SBDS 1 4 0.16 2.05 2.05
165 INT113439 Positive_regulation of OPN1LW 1 2 0.11 0.84 2.01
166 INT351284 Regulation of Localization of AP1M2 1 1 0.04 0.85 1.9
167 INT128058 Regulation of PER1 1 6 0.43 1.82 1.89
168 INT351285 Localization of AP1M2 1 1 0.07 0.79 1.89
169 INT351269 Localization of Fabp4 2 1 0.74 1.9 1.85
170 INT115303 Localization of SNAP25 1 8 0.73 1.43 1.82
171 INT26513 Regulation of Fabp4 1 3 0.45 0.72 1.76
172 INT94934 Negative_regulation of COX1 1 3 0.57 3.27 1.75
173 INT118946 Binding of FABP4 2 4 0.44 3.97 1.71
174 INT135009 Positive_regulation of BPI 1 8 0.54 3.8 1.59
175 INT351211 Regulation of Commd3 2 1 0.18 3.06 1.56
176 INT184206 Protein_catabolism of HRAS 1 22 0.66 7.86 1.46
177 INT15798 Positive_regulation of Gene_expression of TFRC 1 9 0.46 4.99 1.42
178 INT351254 Regulation of Regulation of TNC 1 1 0.14 0.55 1.4
179 INT351303 Regulation of Binding of Cnr2 1 1 0.10 0.66 1.39
180 INT351302 Regulation of Regulation of Cnr1 1 1 0.10 0.78 1.39
181 INT37076 Negative_regulation of Binding of KNG1 1 3 0.14 1.77 1.32
182 INT351270 Phosphorylation of Fabp4 1 1 0.62 1.31 1.31
183 INT307261 Negative_regulation of FABP4 1 4 0.46 1.3 1.3
184 INT70615 Binding of TXNRD1 1 25 0.36 12.15 1.27
185 INT351255 Transcription of OPN1LW 1 1 0.16 1.15 1.27
186 INT116131 Gene_expression of Commd3 1 2 0.53 0.68 1.21
187 INT351210 Transcription of Commd3 1 1 0.31 0.62 1.21
188 INT351212 Negative_regulation of Commd3 2 1 0.17 1.29 1.18
189 INT351256 Regulation of OPN1LW 1 1 0.10 0.55 1.17
190 INT82540 Negative_regulation of TFRC 1 3 0.41 0.77 1.07
191 INT53291 Negative_regulation of Binding of OPN1LW 1 2 0.10 0.67 1.02
192 INT150546 Positive_regulation of Phosphorylation of MAP2K6 1 3 0.49 1.14 0.93
193 INT351266 Regulation of Binding of CLOCK 1 1 0.21 0 0.92
194 INT351265 Regulation of Binding of SRI 1 1 0.28 0 0.92
195 INT351261 Regulation of Binding of PER1 1 1 0.40 0 0.91
196 INT351262 Binding of PER2 1 1 0.31 0 0.91
197 INT351264 Regulation of Binding of PER2 1 1 0.37 0 0.91
198 INT351199 Gene_expression of Ptpn9 2 1 0.20 1 0.89
199 INT351296 Regulation of Maf 1 1 0.01 0.9 0.88
200 INT217683 Localization of BMI1 1 7 0.68 6.28 0.87
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