J:Lab. Invest.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 2 0.38 4.29 1.71
2 INT137162 IFNG Positive_regulation of Gene_expression of CXCL9 1 1 0.45 0.62 0.54
3 INT137157 TNF Positive_regulation of Gene_expression of CXCL9 1 1 0.38 0.61 0.54
4 INT137168 IFNG Positive_regulation of Gene_expression of CXCR3 1 1 0.32 0.34 0.32
5 INT137155 Binding of TLR5 and TLR9 Positive_regulation of Gene_expression of CXCR3 1 1 0.32 0.34 0.32
6 INT137154 Binding of TLR7 and TLR9 Positive_regulation of Gene_expression of CXCR3 1 1 0.34 0.34 0.32
7 INT137156 Binding of TLR5 and TLR7 Positive_regulation of Gene_expression of CXCR3 1 1 0.31 0.34 0.32
8 INT137160 TLR7 Positive_regulation of Gene_expression of CXCR3 1 1 0.35 0.34 0.32
9 INT137158 TLR5 Positive_regulation of Gene_expression of CXCR3 1 1 0.32 0.34 0.32
10 INT137170 CXCL9 Positive_regulation of Binding of CXCR3 1 1 0.44 0.31 0.31
11 INT137159 Binding of TLR7 and TLR9 1 1 0.27 0.33 0.29
12 INT137163 Binding of TLR5 and TLR9 1 1 0.25 0.33 0.29
13 INT137169 Binding of TLR5 and TLR7 1 1 0.25 0.33 0.29
14 INT137166 IL8 Positive_regulation of CXCR2 1 1 0.24 0.28 0.27
15 INT137167 Binding of IFNG and TLR3 1 1 0.24 0.32 0.27
16 INT113809 Negative_regulation of Cpox Negative_regulation of Gene_expression of VEGFA 1 1 0.02 0.97 0.18
17 INT36128 Binding of Scd1 and Mme 1 1 0.00 0 0.09
18 INT120077 Gene_expression of Smad7 Negative_regulation of Positive_regulation of Itk 1 1 0.02 0.27 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT467 Gene_expression of POMC 1 1048 0.78 332.8 394.16
2 INT9158 Gene_expression of Tnf 3 722 0.78 522.01 277.68
3 INT68684 Gene_expression of VEGFA 1 2371 0.78 1742.52 259.2
4 INT49441 Negative_regulation of Cpox 8 494 0.59 303.22 177.46
5 INT867 Gene_expression of IFNA1 1 930 0.78 594.85 168.03
6 INT5116 Gene_expression of IL2 1 670 0.78 291.13 146.69
7 INT5061 Negative_regulation of Mme 1 306 0.59 51.97 136.9
8 INT49439 Gene_expression of Cpox 4 508 0.73 326.97 130.17
9 INT65054 Positive_regulation of Nfkb1 1 285 0.70 149.33 126.73
10 INT82878 Gene_expression of Ccl2 5 201 0.78 164.95 101.35
11 INT940 Negative_regulation of Ptgs1 1 219 0.59 104.34 95.97
12 INT56291 Gene_expression of Ros1 2 503 0.63 274.12 81.5
13 INT5056 Gene_expression of IFNG 2 216 0.78 137.52 74.57
14 INT5969 Gene_expression of Il1a 3 221 0.75 96.31 71.38
15 INT8357 Gene_expression of KNG1 1 153 0.75 77.26 68.66
16 INT11318 Gene_expression of Gtf3a 4 274 0.52 183.82 60.89
17 INT14740 Gene_expression of TGFB1 1 272 0.78 168.48 60.18
18 INT11491 Positive_regulation of KNG1 1 128 0.67 60.41 58.74
19 INT52800 Negative_regulation of Gene_expression of Tnf 1 142 0.59 92.27 55.47
20 INT117223 Gene_expression of TLR4 1 348 0.78 206.18 54.42
21 INT16364 Gene_expression of HLA-DRA 3 234 0.78 118.81 45.01
22 INT613 Gene_expression of Alb 1 268 0.78 149.84 42.78
23 INT9094 Gene_expression of COL7A1 1 277 0.77 143.42 38.73
24 INT133028 Gene_expression of TLR2 1 209 0.73 131.92 36.17
25 INT11292 Gene_expression of Mme 2 77 0.78 20.98 35.85
26 INT67039 Positive_regulation of Cpox 1 144 0.65 98.4 33.77
27 INT81530 Gene_expression of Nfkb1 2 93 0.78 48.58 32.58
28 INT14497 Gene_expression of GRP 5 82 0.78 17.67 32.27
29 INT99688 Negative_regulation of Gene_expression of VEGFA 1 274 0.58 201.8 31.1
30 INT121663 Gene_expression of CXCR3 1 76 0.77 50.96 30.62
31 INT9993 Positive_regulation of Gene_expression of IL2 1 131 0.69 46.27 30.04
32 INT4861 Localization of GRP 2 84 0.80 8.26 28.03
33 INT52801 Regulation of Gene_expression of Tnf 2 55 0.62 48.74 26.59
34 INT17739 Gene_expression of S100B 1 226 0.78 132.7 26.4
35 INT94335 Positive_regulation of CXCL10 1 71 0.58 50.69 23
36 INT6868 Gene_expression of GFAP 2 136 0.78 84.65 22.7
37 INT14733 Positive_regulation of Gene_expression of TGFB1 1 71 0.69 49.89 22.2
38 INT69993 Positive_regulation of Gene_expression of Cpox 2 93 0.55 69.4 22.05
39 INT14737 Gene_expression of FN1 1 117 0.78 78.74 18.99
40 INT84171 Negative_regulation of Gene_expression of Ccl2 2 30 0.58 26.37 18.28
41 INT117220 Positive_regulation of TLR4 1 64 0.69 53.61 17.33
42 INT10214 Gene_expression of VIM 1 153 0.78 115.88 16.29
43 INT15166 Positive_regulation of Mme 2 40 0.70 13.01 16.24
44 INT26314 Positive_regulation of MMP3 1 48 0.67 22.14 16.17
45 INT61172 Gene_expression of PRKCA 1 34 0.77 8.89 15.47
46 INT14453 Localization of Mme 1 44 0.80 2.46 14.75
47 INT69878 Positive_regulation of Gene_expression of Gtf3a 2 48 0.29 36.78 13.57
48 INT52905 Gene_expression of Cd4 1 84 0.78 45.68 12.75
49 INT8224 Gene_expression of CHGA 4 73 0.75 53.63 12.31
50 INT83611 Negative_regulation of Gene_expression of Cpox 1 55 0.29 31.09 11.5
51 INT48203 Positive_regulation of Tgfb1 1 67 0.70 41.31 11.07
52 INT23177 Negative_regulation of Gene_expression of HLA-DRA 1 50 0.44 16.99 10.55
53 INT61171 Gene_expression of S100A8 1 92 0.76 57.74 9.98
54 INT17741 Gene_expression of MBP 2 67 0.78 23.67 9.65
55 INT137181 Gene_expression of CXCL9 3 25 0.65 13.09 9.56
56 INT54834 Gene_expression of Col2a1 2 48 0.72 13.5 9.41
57 INT78226 Gene_expression of Mbp 1 43 0.75 22.14 7.79
58 INT8603 Binding of Mme 1 28 0.48 1.42 7.64
59 INT95133 Gene_expression of FASLG 5 38 0.75 44.09 7.51
60 INT121496 Gene_expression of TERT 1 107 0.78 45.6 7.42
61 INT82881 Regulation of Ccl2 1 19 0.57 15.29 7.19
62 INT83531 Gene_expression of KITLG 3 54 0.65 26 7.07
63 INT60700 Gene_expression of Itgax 2 93 0.71 51.89 6.57
64 INT3731 Negative_regulation of Neu1 2 17 0.39 8.35 5.67
65 INT83290 Regulation of Gene_expression of Ccl2 3 8 0.59 9.06 5.56
66 INT15284 Positive_regulation of Lgals3 4 21 0.47 8.88 5.52
67 INT21609 Positive_regulation of RASGRP1 1 58 0.50 40.78 5.47
68 INT85653 Regulation of Gene_expression of Cpox 1 24 0.24 20.55 5.22
69 INT137179 Positive_regulation of CXCL9 4 11 0.65 7.73 5.11
70 INT120073 Positive_regulation of Itk 1 34 0.44 23.45 5.09
71 INT14753 Binding of GRP 1 15 0.48 2.28 5.09
72 INT95131 Binding of Cd4 1 27 0.37 21.62 5.07
73 INT19187 Gene_expression of Lgals3 2 24 0.73 19.72 5.03
74 INT20055 Gene_expression of CRTAC1 1 19 0.58 15.49 4.73
75 INT137178 Gene_expression of TLR3 1 46 0.72 24.97 4.33
76 INT55743 Gene_expression of Timp2 1 25 0.31 8.95 4.3
77 INT57273 Positive_regulation of Gene_expression of FN1 1 26 0.47 17.83 4.2
78 INT91333 Gene_expression of CXCL11 2 11 0.65 10.96 4.1
79 INT37380 Negative_regulation of Sis 1 31 0.55 19.89 3.92
80 INT120072 Gene_expression of Smad7 5 38 0.74 20.87 3.69
81 INT12083 Regulation of TGFB1 2 22 0.53 15.4 3.6
82 INT137180 Binding of CXCR3 1 10 0.41 4.24 3.53
83 INT23467 Gene_expression of S100P 3 13 0.78 8.01 3.44
84 INT96542 Negative_regulation of SMN1 1 14 0.51 10.72 3.11
85 INT99574 Positive_regulation of KITLG 1 10 0.39 6.74 2.96
86 INT69768 Negative_regulation of Pscs 2 7 0.51 4.76 2.82
87 INT11291 Positive_regulation of Gene_expression of Mme 1 6 0.61 5.93 2.81
88 INT129722 Gene_expression of TNFRSF10D 2 4 0.58 6.75 2.66
89 INT15850 Positive_regulation of Trim25 2 4 0.43 5.64 2.52
90 INT79261 Positive_regulation of Gene_expression of COL1A1 1 24 0.36 7.49 2.45
91 INT49454 Negative_regulation of Gene_expression of Gtf3a 2 13 0.08 9.99 2.43
92 INT95136 Binding of FASLG 1 6 0.33 8.01 2.41
93 INT39212 Binding of Ttr 1 14 0.48 9.62 2.31
94 INT21611 Negative_regulation of RASGRP1 1 20 0.35 11.76 2.15
95 INT90219 Gene_expression of Lgals1 1 6 0.20 3.47 1.94
96 INT90217 Positive_regulation of Lgals1 3 1 0.15 2.06 1.78
97 INT95134 Binding of TH1L 1 6 0.47 3.67 1.68
98 INT69026 Gene_expression of Mog 2 4 0.45 6.9 1.68
99 INT92934 Gene_expression of GRPR 1 2 0.67 5.13 1.57
100 INT120071 Negative_regulation of Positive_regulation of Tgfb1 1 4 0.16 4.06 1.55
101 INT90218 Localization of Lgals1 1 3 0.18 1.77 1.51
102 INT129712 Positive_regulation of Gene_expression of TERT 1 12 0.70 7.3 1.44
103 INT9784 Binding of B2M 1 9 0.47 6.18 1.44
104 INT54831 Regulation of Gene_expression of Col2a1 2 4 0.39 2.3 1.31
105 INT8063 Regulation of RASGRP1 1 15 0.36 9.15 1.3
106 INT120075 Gene_expression of Itk 1 11 0.43 6.39 1.27
107 INT120076 Positive_regulation of Gene_expression of Smad7 3 16 0.65 11.33 1.25
108 INT137177 Positive_regulation of CXCL11 1 6 0.67 4.17 1.13
109 INT137175 Positive_regulation of Gene_expression of CXCL9 2 1 0.47 1.32 1.07
110 INT129726 Regulation of Nfkbia 1 2 0.06 1.63 1.05
111 INT47551 Negative_regulation of Ptprt 1 2 0.37 0.35 1.05
112 INT91334 Localization of CXCL11 1 3 0.73 1.97 1
113 INT77054 Regulation of Gene_expression of Timp2 1 2 0.05 0.7 0.96
114 INT24974 Negative_regulation of Naglu 1 5 0.42 2.68 0.9
115 INT129721 Positive_regulation of TNFRSF10D 1 3 0.51 2.75 0.9
116 INT113815 Gene_expression of TFF1 1 23 0.75 17.53 0.87
117 INT14085 Localization of Cd4 1 3 0.44 1.22 0.79
118 INT101236 Gene_expression of LARGE 1 10 0.75 3.63 0.75
119 INT113813 Positive_regulation of REG1B 2 3 0.60 1.19 0.72
120 INT137183 Positive_regulation of Gene_expression of CXCL11 1 3 0.45 2.38 0.7
121 INT113814 Gene_expression of REG1B 2 4 0.67 1.45 0.66
122 INT47553 Gene_expression of ARSH 1 11 0.42 4.93 0.65
123 INT38968 Localization of Ctrc 1 4 0.69 1 0.64
124 INT95135 Negative_regulation of Gene_expression of FASLG 1 4 0.20 2.99 0.64
125 INT92935 Binding of GRPR 1 2 0.32 1.99 0.62
126 INT90216 Transcription of Lgals1 1 1 0.11 0.67 0.59
127 INT96347 Gene_expression of DAB2 8 1 0.66 11.55 0.58
128 INT68923 Gene_expression of CA7.1 1 1 0.01 0.73 0.56
129 INT16671 Gene_expression of MBTPS1 1 7 0.30 4.8 0.52
130 INT120074 Regulation of Gene_expression of Smad7 1 1 0.58 2.05 0.5
131 INT45981 Negative_regulation of HRASLS 1 5 0.13 3.83 0.45
132 INT92933 Gene_expression of TNFRSF9 1 3 0.75 1.65 0.45
133 INT108650 Positive_regulation of Gene_expression of KITLG 1 2 0.33 2.57 0.41
134 INT95132 Negative_regulation of Binding of FASLG 1 1 0.18 0.63 0.38
135 INT69680 Positive_regulation of Positive_regulation of Tgfb1 1 3 0.67 1.04 0.35
136 INT96344 Transcription of DAB2 4 1 0.61 6.32 0.35
137 INT129716 Gene_expression of Birc3 1 1 0.07 1.18 0.35
138 INT16808 Binding of Scd1 1 5 0.00 7.18 0.33
139 INT96351 Negative_regulation of Gene_expression of DAB2 4 1 0.50 6.09 0.3
140 INT96346 Positive_regulation of Gene_expression of DAB2 4 1 0.59 5.72 0.29
141 INT113811 Positive_regulation of Gene_expression of REG1B 1 1 0.60 0.3 0.28
142 INT113812 Localization of REG1B 1 1 0.69 0.35 0.27
143 INT137176 Positive_regulation of Localization of CXCL11 1 1 0.61 0.31 0.27
144 INT113810 Positive_regulation of Localization of REG1B 1 1 0.60 0.35 0.27
145 INT78227 Positive_regulation of Gene_expression of Mbp 1 3 0.43 2.54 0.25
146 INT47550 Gene_expression of Naglu 2 4 0.44 2.02 0.23
147 INT14949 Binding of TIPRL 1 1 0.00 0.53 0.23
148 INT47548 Negative_regulation of Glb1 1 3 0.55 1.59 0.21
149 INT58620 Positive_regulation of Gene_expression of MBTPS1 1 1 0.02 0.37 0.17
150 INT129713 Positive_regulation of Gene_expression of LARGE 1 1 0.49 1.01 0.16
151 INT113808 Positive_regulation of Mthfs 1 1 0.01 0.81 0.12
152 INT96349 Positive_regulation of Transcription of DAB2 1 1 0.59 1.52 0.09
153 INT37525 Gene_expression of Mkl1 1 1 0.16 0.54 0.09
154 INT96350 Regulation of Transcription of DAB2 1 1 0.53 1.49 0.08
155 INT96343 Positive_regulation of DAB2 1 1 0.40 1.51 0.08
156 INT96345 Negative_regulation of DAB2 1 1 0.36 1.51 0.08
157 INT47549 Negative_regulation of Hexdc 1 1 0.33 0.36 0.07
158 INT96348 Regulation of Gene_expression of DAB2 1 1 0.53 1.21 0.05
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