J:Lancet

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT13519 Binding of HLA-DQA1 and HLA-DRB4 1 1 0.03 0.88 0.05

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 1 2008 0.81 518.3 1408.65
2 INT158 Localization of Prl 3 2431 0.81 378.96 952.2
3 INT6483 Gene_expression of TNF 2 3152 0.78 2515.62 929.82
4 INT728 Positive_regulation of Penk 1 1068 0.70 186.9 636.87
5 INT155 Positive_regulation of Prl 4 1233 0.70 317.93 457.82
6 INT443 Localization of POMC 2 1020 0.81 284.52 443.17
7 INT50058 Negative_regulation of Cpox 2 907 0.58 426.28 428.29
8 INT467 Gene_expression of POMC 7 1048 0.78 332.8 394.16
9 INT18357 Gene_expression of TRPV1 7 825 0.78 307.11 382.81
10 INT157 Positive_regulation of Localization of Prl 2 790 0.70 104.54 374.78
11 INT439 Localization of Gnrh1 2 976 0.81 100.96 363.25
12 INT720 Positive_regulation of POMC 8 807 0.70 237.37 353.83
13 INT5059 Positive_regulation of TNF 1 1050 0.70 896.51 322.81
14 INT9381 Positive_regulation of TRPV1 1 523 0.70 187.4 276.05
15 INT1893 Localization of Gh 6 1041 0.79 340.23 256.58
16 INT738 Regulation of POMC 8 459 0.62 111.19 243.74
17 INT2391 Negative_regulation of PTGS1 1 501 0.59 207.62 205.6
18 INT156 Negative_regulation of Prl 2 542 0.59 131.97 192.24
19 INT528 Gene_expression of Prl 3 693 0.78 217.18 192.2
20 INT739 Negative_regulation of POMC 3 358 0.59 102.28 166.77
21 INT3448 Positive_regulation of Gh 3 521 0.69 180.03 161.18
22 INT1878 Binding of HLA-B 3 440 0.48 321.16 127.36
23 INT695 Binding of POMC 2 304 0.48 56.66 126.85
24 INT6128 Positive_regulation of Localization of POMC 1 256 0.70 68.77 121.64
25 INT9235 Negative_regulation of Gene_expression of TNF 1 346 0.59 252.98 118.61
26 INT90 Localization of Gast 1 400 0.81 137.67 113
27 INT1530 Regulation of Gh 1 382 0.61 115.96 112.47
28 INT397 Localization of SST 1 232 0.81 58.05 101.19
29 INT5865 Positive_regulation of Localization of Gh 3 282 0.69 84.86 93.5
30 INT214 Localization of AVP 3 370 0.81 208.51 91.09
31 INT48767 Negative_regulation of NOS1 2 312 0.59 154.25 90.32
32 INT55944 Positive_regulation of Cpox 1 214 0.57 105.14 81.4
33 INT1498 Gene_expression of Gh 2 521 0.75 220.84 81.16
34 INT148 Positive_regulation of Gnrhr 1 182 0.70 47.44 79.64
35 INT749 Gene_expression of HLA-B 1 341 0.75 224.12 77.37
36 INT1497 Negative_regulation of Gh 2 415 0.59 192.95 74.71
37 INT2055 Regulation of Gnrh1 1 185 0.62 23.65 71.26
38 INT8388 Positive_regulation of Vip 1 142 0.70 39.72 67.61
39 INT3375 Gene_expression of IGHE 3 535 0.77 387.47 65.46
40 INT9408 Positive_regulation of Crp 1 296 0.69 242.27 57.35
41 INT83602 Positive_regulation of Gene_expression of TRPV1 1 114 0.70 51.19 56.35
42 INT5453 Regulation of Localization of POMC 1 114 0.62 20.56 56.34
43 INT4241 Regulation of CALCA 1 87 0.62 28.19 55.29
44 INT49436 Binding of TRPV1 1 145 0.48 38.35 55.08
45 INT35975 Regulation of Cpox 1 109 0.39 57.88 49.69
46 INT937 Positive_regulation of Oxt 1 195 0.70 37.82 49.3
47 INT22454 Regulation of Crp 2 213 0.62 160.67 49.24
48 INT1197 Negative_regulation of Localization of POMC 1 109 0.59 28.29 48.02
49 INT654 Localization of REN 3 250 0.81 75.12 47.86
50 INT375 Positive_regulation of REN 2 293 0.70 152.46 47.55
51 INT683 Positive_regulation of AVP 1 173 0.70 74.55 46.41
52 INT619 Positive_regulation of Positive_regulation of Prl 2 116 0.70 22.69 45.06
53 INT4216 Gene_expression of CD40LG 1 328 0.78 256.02 44.23
54 INT8824 Regulation of Vip 1 95 0.62 15.7 43.63
55 INT1894 Negative_regulation of Localization of Gh 1 168 0.58 64.12 43.56
56 INT30 Gene_expression of Gast 2 158 0.78 99 41.45
57 INT685 Regulation of AVP 3 124 0.62 34.9 39.91
58 INT692 Negative_regulation of SST 1 72 0.59 28.68 34.52
59 INT16960 Gene_expression of Crp 1 166 0.76 116.21 34.07
60 INT666 Gene_expression of Jun 1 124 0.78 54.61 33.67
61 INT691 Binding of SST 1 67 0.48 24.66 32.67
62 INT610 Regulation of PENK 1 47 0.62 14.17 31.55
63 INT23435 Positive_regulation of NGF 1 54 0.70 32.41 30.11
64 INT660 Negative_regulation of REN 1 194 0.59 82.06 29.46
65 INT91 Positive_regulation of Localization of Gast 1 96 0.70 23.22 29.36
66 INT7035 Regulation of CGA 1 87 0.45 29.04 28.45
67 INT6174 Regulation of Gene_expression of POMC 2 49 0.61 9.75 27.69
68 INT9682 Positive_regulation of IGF1 1 238 0.70 120.03 26.36
69 INT95481 Regulation of Gene_expression of TRPV1 3 48 0.62 29.3 26.28
70 INT29 Negative_regulation of Gast 1 74 0.59 24.85 24.96
71 INT2614 Gene_expression of CGA 2 187 0.78 105.89 24.77
72 INT10240 Gene_expression of Gap43 1 58 0.78 22.11 24.45
73 INT682 Negative_regulation of AVP 1 97 0.59 50.67 23.91
74 INT39914 Negative_regulation of Cyp1a2 1 44 0.58 10.04 22
75 INT693 Negative_regulation of Localization of SST 1 46 0.59 8.57 21.75
76 INT6127 Regulation of Localization of AVP 1 60 0.62 15.12 20.84
77 INT8765 Positive_regulation of Cyp3a23/3a1 1 63 0.67 22.28 20.39
78 INT18010 Positive_regulation of CD40LG 1 122 0.70 100.8 18.46
79 INT667 Negative_regulation of Hrh2 1 38 0.58 18.11 18.01
80 INT10841 Positive_regulation of Gene_expression of Gh 1 101 0.59 45.39 16.96
81 INT213 Negative_regulation of Localization of AVP 2 46 0.59 19.78 16.79
82 INT653 Negative_regulation of Localization of REN 1 67 0.59 20.33 16.7
83 INT6129 Positive_regulation of Localization of AVP 1 63 0.70 30.44 16.64
84 INT899 Gene_expression of F13A1 1 122 0.70 78.02 16.26
85 INT9197 Binding of PTGS1 1 44 0.48 18.48 16.26
86 INT2480 Negative_regulation of Got1 1 43 0.51 14.47 16.09
87 INT36554 Gene_expression of PRSS1 1 70 0.78 50.25 15.33
88 INT3545 Positive_regulation of Mtx1 1 27 0.42 11.97 14.83
89 INT1888 Protein_catabolism of F13A1 4 97 0.99 63.48 14.82
90 INT663 Negative_regulation of Adrb3 2 55 0.59 15.95 14.68
91 INT56651 Binding of HLA-DRB1 2 58 0.48 52.25 13.68
92 INT27627 Binding of Rac1 2 41 0.41 22.88 13.68
93 INT655 Positive_regulation of Localization of REN 1 86 0.70 32.41 13.56
94 INT18191 Negative_regulation of Cyp3a23/3a1 1 48 0.57 10.21 13.38
95 INT635 Negative_regulation of MAOB 3 51 0.59 24.5 12.66
96 INT3104 Negative_regulation of CGA 1 76 0.54 29.81 12.23
97 INT4047 Binding of F13A1 5 105 0.43 66.54 11.81
98 INT744 Positive_regulation of PTH 1 130 0.70 95.02 11.7
99 INT661 Gene_expression of REN 3 100 0.78 48.21 11.36
100 INT686 Negative_regulation of Sct 1 35 0.59 9.59 11.32
101 INT82950 Positive_regulation of Gdnf 1 36 0.51 11.72 10.5
102 INT74812 Negative_regulation of Positive_regulation of Cpox 1 17 0.34 10.1 9.94
103 INT21952 Gene_expression of GDNF 1 42 0.78 20.32 9.62
104 INT11679 Negative_regulation of F13A1 1 55 0.54 33.69 9.43
105 INT50055 Negative_regulation of Rac1 1 36 0.50 19.74 8.98
106 INT684 Binding of AVP 1 38 0.48 13.9 8.85
107 INT5164 Negative_regulation of Ldlr 1 83 0.58 55.01 7.87
108 INT17996 Binding of Crp 1 40 0.37 31.4 7.8
109 INT1123 Positive_regulation of CD79A 1 74 0.70 51.96 7.14
110 INT717 Regulation of F2 1 29 0.61 17.46 6.99
111 INT31333 Gene_expression of Esr2 2 19 0.69 8.78 6.83
112 INT13520 Binding of HLA-DRB4 1 30 0.42 32.65 6.74
113 INT10610 Negative_regulation of Plg 1 22 0.40 11.81 6.74
114 INT11826 Positive_regulation of LDLR 3 62 0.62 45.09 6.21
115 INT76581 Regulation of Negative_regulation of NOS1 1 14 0.45 7.49 4.4
116 INT5320 Gene_expression of PTGFR 1 18 0.59 12.99 3.7
117 INT31 Negative_regulation of Gene_expression of Gast 1 10 0.42 5.3 3.34
118 INT542 Gene_expression of Fshb 1 14 0.75 5.22 3.24
119 INT1924 Regulation of PLAT 1 11 0.60 6.3 3.16
120 INT743 Negative_regulation of Salpa1 1 16 0.57 8.75 3.1
121 INT550 Negative_regulation of LDLR 1 66 0.43 44.71 3.04
122 INT67985 Regulation of Saa 1 9 0.44 9.36 3
123 INT54072 Gene_expression of GAP43 2 14 0.67 5.04 2.83
124 INT10893 Binding of VWF 2 27 0.47 25.02 2.82
125 INT17039 Regulation of Hr 1 11 0.27 5.22 2.58
126 INT699 Positive_regulation of A2M 1 16 0.66 10.49 2.5
127 INT82737 Regulation of Hmox2 1 7 0.14 4.6 2.44
128 INT646 Binding of Mb 1 37 0.41 6.13 2.25
129 INT664 Positive_regulation of Fgg 1 14 0.46 8.75 2.11
130 INT101412 Negative_regulation of CDAN1 2 16 0.57 6.41 1.61
131 INT16475 Regulation of GAP43 1 3 0.44 1.25 1.43
132 INT61395 Negative_regulation of Negative_regulation of NOS1 1 5 0.30 1.83 1.25
133 INT13659 Positive_regulation of Rsph1 1 2 0.22 1.02 1.25
134 INT28244 Protein_catabolism of TCN1 3 7 0.96 0.89 1.11
135 INT41009 Gene_expression of Ubd 1 2 0.52 1.67 1.07
136 INT2981 Negative_regulation of Gene_expression of CGA 2 14 0.42 3.41 1.05
137 INT49505 Binding of NOTCH3 1 6 0.47 6.4 1.03
138 INT16479 Positive_regulation of Serpinf2 1 2 0.05 1.2 0.9
139 INT7619 Regulation of TPO 1 3 0.24 3.09 0.89
140 INT7620 Localization of TPO 1 4 0.26 5.35 0.88
141 INT54073 Positive_regulation of Gene_expression of GAP43 1 3 0.51 0.74 0.86
142 INT36869 Negative_regulation of F12 4 2 0.16 1.63 0.65
143 INT67986 Binding of C1QL1 1 2 0.47 0.72 0.63
144 INT687 Negative_regulation of Negative_regulation of Sct 1 2 0.42 1.27 0.59
145 INT656 Positive_regulation of ATP6AP2 4 10 0.18 2.89 0.58
146 INT23950 Negative_regulation of Acpp 3 6 0.58 2.51 0.5
147 INT40583 Regulation of ALPI 1 4 0.45 1.87 0.48
148 INT662 Gene_expression of ATP6AP2 1 3 0.28 2.06 0.35
149 INT40839 Negative_regulation of PFKP 1 1 0.09 0.2 0.24
150 INT56652 Protein_catabolism of HLA-DRB1 2 1 0.00 1.77 0.19
151 INT659 Regulation of ATP6AP2 1 1 0.10 0.13 0.19
152 INT658 Positive_regulation of Gene_expression of ATP6AP2 1 1 0.17 0.14 0.19
153 INT657 Localization of ATP6AP2 1 1 0.26 0.07 0.17
154 INT41008 Binding of Ubd 1 1 0.31 0.66 0.17
155 INT31433 Binding of CD9 1 1 0.36 1.36 0.13
156 INT41112 Negative_regulation of Regulation of CGA 1 1 0.19 0.25 0.09
157 INT30434 Negative_regulation of Negative_regulation of Acpp 1 1 0.02 0.25 0
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