J:Med. Hypotheses

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT164362 Binding of NLRP1 and VTA1 1 7 0.15 2.37 4.67
2 INT164365 Positive_regulation of Binding of NLRP1 and VTA1 1 2 0.14 0.6 1.21
3 INT164363 Regulation of Binding of NLRP1 and VTA1 1 1 0.14 0.45 0.86
4 INT164364 Binding of DRD2 and SUGT1 2 1 0.06 0.33 0.77

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT11377 Positive_regulation of Ngf 1 331 0.70 206.5 238
2 INT10194 Positive_regulation of IL6 4 702 0.70 600.62 183.38
3 INT48953 Positive_regulation of Nos2 1 486 0.70 239.85 131.87
4 INT5008 Localization of Calca 1 204 0.81 80.35 125.16
5 INT56130 Gene_expression of MC1R 1 259 0.78 62.7 97.55
6 INT54571 Positive_regulation of NFKB1 1 263 0.70 138.99 87.32
7 INT17546 Negative_regulation of Ngf 1 135 0.59 60.28 77.19
8 INT109431 Gene_expression of Trpa1 1 123 0.78 51.84 59.98
9 INT21737 Binding of MC1R 1 129 0.48 45.45 56.54
10 INT17881 Gene_expression of LEP 2 278 0.78 221.61 48.31
11 INT654 Localization of REN 1 250 0.81 75.12 47.86
12 INT9094 Gene_expression of COL7A1 2 277 0.77 143.42 38.73
13 INT93534 Gene_expression of Tnfsf11 1 185 0.77 119.26 33.66
14 INT21900 Gene_expression of Mthfd1 1 150 0.75 69.47 27.03
15 INT49774 Binding of DRD2 3 48 0.48 17.42 20.73
16 INT164366 Localization of NLRP1 2 26 0.71 5.9 16.54
17 INT3002 Binding of SUGT1 1 62 0.24 55.9 14.91
18 INT54924 Gene_expression of RLS 1 67 0.62 83.2 14.25
19 INT86646 Positive_regulation of SCN10A 2 71 0.69 50.61 13.24
20 INT91817 Positive_regulation of RETNLB 2 22 0.34 21.4 13.12
21 INT83201 Gene_expression of NOS3 1 93 0.78 47.16 12.48
22 INT145425 Positive_regulation of NLRP1 1 19 0.47 6.93 12.09
23 INT14513 Localization of Ghrl 3 52 0.78 29.26 11.63
24 INT107291 Positive_regulation of Ghrl 2 58 0.67 44.6 9.68
25 INT9899 Gene_expression of Vwf 1 91 0.74 45.06 9.13
26 INT164368 Localization of VTA1 2 5 0.53 3.33 8.47
27 INT54368 Positive_regulation of VTA1 3 13 0.59 3.81 8.13
28 INT15490 Negative_regulation of Gene_expression of COL7A1 1 40 0.58 25.97 7.18
29 INT15812 Localization of CALCB 1 10 0.30 8.77 6.36
30 INT17641 Gene_expression of NLRP1 1 33 0.73 8.85 6.02
31 INT103880 Positive_regulation of DRD2 1 9 0.67 5.57 5.93
32 INT84909 Positive_regulation of SUGT1 1 22 0.08 22.01 5.43
33 INT10888 Binding of Vwf 2 32 0.46 22.87 5.21
34 INT117855 Negative_regulation of Ghrl 1 29 0.57 17.52 5
35 INT57274 Positive_regulation of Gene_expression of COL7A1 1 50 0.69 24.19 4.72
36 INT4097 Localization of Pth 4 66 0.81 47.17 4.36
37 INT141285 Positive_regulation of Localization of Ghrl 2 11 0.63 9.38 3.86
38 INT15814 Positive_regulation of Localization of CALCB 1 4 0.20 2.49 3.82
39 INT98624 Regulation of Aqp4 2 27 0.62 30.76 3.77
40 INT125622 Regulation of NLRP1 1 7 0.44 1.84 3.62
41 INT164367 Negative_regulation of Localization of NLRP1 1 3 0.34 1.43 2.5
42 INT67162 Gene_expression of HSPA1A 1 16 0.68 7.13 2.17
43 INT103298 Binding of CALCR 1 5 0.47 6.03 2.15
44 INT142056 Binding of NLRP1 2 7 0.47 1.7 2.02
45 INT164017 Negative_regulation of Localization of Ghrl 1 2 0.53 3.12 1.88
46 INT67488 Binding of Pc 1 8 0.31 4.6 1.13
47 INT93424 Binding of SLC45A2 1 3 0.36 0.58 0.95
48 INT161118 Regulation of Cth 1 2 0.27 1.46 0.72
49 INT165399 Phosphorylation of Dspp 1 1 0.01 0.63 0.44
50 INT161404 Negative_regulation of Pc 1 3 0.49 0.95 0.2
51 INT159640 Negative_regulation of Regulation of Aqp4 1 1 0.42 0.78 0.18
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