J:Mol. Cell. Endocrinol.

This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT2161	Gnrh1 Positive_regulation of Localization of LH	33	2	0.73	0.87	14.34
2	INT73775	Binding of GH1 and GHR	4	1	0.35	0.68	0.8
3	INT73776	Regulation of Binding of GH1 and GHR	2	1	0.26	0.16	0.75
4	INT85736	Positive_regulation of Il1b Positive_regulation of Tpgs2	1	1	0.02	0.2	0.48
5	INT85735	Il1b Positive_regulation of Tpgs2	1	1	0.02	0.2	0.47
6	INT48715	PTGER2 Regulation of Gene_expression of SERPINE1	1	2	0.21	0.6	0.44
7	INT48716	IL1B Regulation of Gene_expression of SERPINE1	1	2	0.42	0.59	0.44
8	INT48714	PTGER2 Negative_regulation of Gene_expression of SERPINE1	1	2	0.15	0.28	0.38
9	INT6121	Gmcl1 Regulation of Gene_expression of Penk	1	1	0.03	0	0.36
10	INT21301	Gnrh1 Negative_regulation of LH	2	1	0.28	0	0.3
11	INT74433	Binding of INS and Cpe	2	1	0.03	0	0.25
12	INT36171	Ptger2 Positive_regulation of Localization of Gnrh1	1	2	0.10	0	0.25
13	INT48713	PTGER1 Negative_regulation of Gene_expression of SERPINE1	1	1	0.02	0.28	0.22
14	INT51034	Slc30a2 Positive_regulation of Enpep	1	1	0.01	0	0.19
15	INT21300	Gnrh1 Negative_regulation of Localization of LH	1	1	0.28	0	0.17
16	INT21302	Gnrh1 Positive_regulation of Positive_regulation of Fshr	1	1	0.25	0	0.15
17	INT34101	NA Positive_regulation of Localization of Gnrh1	2	1	0.03	0	0.12
18	INT21310	Binding of Gnrh1 and Positive_regulation of Localization of CGA	1	1	0.00	0	0.09
19	INT6120	Gmcl1 Positive_regulation of Pigm	1	1	0.01	0	0.07

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT5200	Gene_expression of Fos	1	3083	0.78	894.43	1639.02
2	INT2542	Localization of Calca	4	2008	0.81	518.3	1408.65
3	INT796	Gene_expression of Penk	2	1902	0.78	275.47	1057.59
4	INT158	Localization of Prl	18	2431	0.81	378.96	952.2
5	INT1912	Gene_expression of Calca	1	1152	0.78	453.25	739.84
6	INT155	Positive_regulation of Prl	4	1233	0.70	317.93	457.82
7	INT1045	Localization of LH	4	1211	0.81	87.04	456.25
8	INT2540	Negative_regulation of Calca	1	538	0.59	172.11	384.38
9	INT18357	Gene_expression of TRPV1	1	825	0.78	307.11	382.81
10	INT6580	Negative_regulation of Ptgs1	1	929	0.59	381.53	376.26
11	INT157	Positive_regulation of Localization of Prl	15	790	0.70	104.54	374.78
12	INT439	Localization of Gnrh1	13	976	0.81	100.96	363.25
13	INT876	Localization of Gh1	11	843	0.80	67.75	340.82
14	INT5979	Gene_expression of Oprd1	1	428	0.78	75.64	320.32
15	INT161	Regulation of Localization of Prl	3	615	0.62	65.37	298.66
16	INT886	Gene_expression of Pomc	1	676	0.78	129.87	295.98
17	INT5597	Gene_expression of Pdyn	5	433	0.78	62.97	235.47
18	INT1665	Positive_regulation of Pag1	1	270	0.68	186.63	229.87
19	INT767	Localization of Gnrhr	4	565	0.80	106.68	214.57
20	INT528	Gene_expression of Prl	1	693	0.78	217.18	192.2
21	INT159	Negative_regulation of Localization of Prl	11	416	0.59	55.34	171.8
22	INT1114	Localization of Ins1	1	748	0.80	192.95	165.48
23	INT5127	Localization of Lhb	2	488	0.80	50.48	162.66
24	INT1044	Negative_regulation of Localization of LH	1	358	0.59	25.95	151.31
25	INT880	Positive_regulation of Localization of Gh1	8	304	0.70	14.79	150.23
26	INT2451	Positive_regulation of Avp	4	355	0.70	102.66	147.69
27	INT2379	Positive_regulation of Localization of LH	1	349	0.70	27.86	144.53
28	INT2780	Regulation of Gene_expression of Penk	2	265	0.62	32.45	143.88
29	INT1273	Gene_expression of Avp	2	356	0.78	90.56	138.7
30	INT1047	Negative_regulation of LH	3	314	0.59	53.71	135.89
31	INT7395	Localization of GNRH1	2	399	0.81	62.88	117.68
32	INT4207	Regulation of Avp	5	267	0.62	63.72	115.33
33	INT1793	Localization of CGA	3	379	0.81	67.38	114.69
34	INT11381	Positive_regulation of IL1B	1	330	0.70	209.31	100.9
35	INT874	Positive_regulation of Gh1	2	244	0.70	27.17	97.98
36	INT4822	Localization of Ca2	2	417	0.80	99.57	96.45
37	INT2122	Negative_regulation of Localization of Gnrh1	4	226	0.59	26.92	92.04
38	INT5594	Regulation of Pdyn	1	137	0.62	27.04	86.63
39	INT4289	Positive_regulation of Localization of Gnrh1	5	202	0.70	12.3	84.01
40	INT4631	Positive_regulation of Sst	1	127	0.70	17.37	83.29
41	INT1309	Positive_regulation of Localization of Gnrhr	3	152	0.69	24.25	81.56
42	INT148	Positive_regulation of Gnrhr	2	182	0.70	47.44	79.64
43	INT2155	Negative_regulation of Sst	1	111	0.59	16.58	77.74
44	INT3657	Gene_expression of Ins1	1	514	0.78	321.69	75.76
45	INT881	Negative_regulation of Localization of Gh1	2	164	0.58	15.1	75.28
46	INT5593	Positive_regulation of Gene_expression of Pdyn	1	114	0.70	29.1	74.46
47	INT10274	Positive_regulation of Il1b	1	123	0.70	79.76	73.56
48	INT8962	Gene_expression of Cpe	4	110	0.71	39.67	71.67
49	INT5128	Positive_regulation of Lhb	2	232	0.69	44.23	71.26
50	INT2123	Positive_regulation of Gnrh1	1	209	0.70	24.2	68.97
51	INT1988	Positive_regulation of Localization of Ins1	1	254	0.69	59.25	68.37
52	INT6824	Regulation of Gene_expression of Pdyn	2	114	0.62	9.48	66.73
53	INT9196	Gene_expression of PTGS1	1	215	0.77	96.99	60.5
54	INT1794	Regulation of Localization of CGA	1	136	0.57	13.39	59.07
55	INT5710	Negative_regulation of Localization of Lhb	1	146	0.57	20.51	58.33
56	INT1200	Negative_regulation of Ins1	1	274	0.58	155.17	56.14
57	INT5598	Negative_regulation of Pdyn	2	95	0.59	14.4	55.43
58	INT1579	Gene_expression of PRL	3	279	0.78	119.2	55.41
59	INT6116	Regulation of Gene_expression of Oprd1	1	69	0.62	16.43	54
60	INT1977	Negative_regulation of Positive_regulation of Prl	2	98	0.59	17.06	47.88
61	INT375	Positive_regulation of REN	1	293	0.70	152.46	47.55
62	INT48718	Positive_regulation of PRKCA	1	109	0.69	36.16	46.49
63	INT531	Gene_expression of GH1	2	376	0.75	193.45	46.24
64	INT619	Positive_regulation of Positive_regulation of Prl	2	116	0.70	22.69	45.06
65	INT5214	Localization of Cpe	1	49	0.73	13.3	44.36
66	INT5130	Regulation of GNRH1	1	139	0.62	31.95	42.08
67	INT4449	Positive_regulation of NA	2	179	0.55	40.26	37.82
68	INT65055	Negative_regulation of Nfkb1	2	83	0.58	44.85	34.94
69	INT67613	Positive_regulation of PPARG	1	94	0.70	69.15	34.38
70	INT2699	Binding of Cpe	1	40	0.48	7.07	33.64
71	INT5868	Positive_regulation of GNRH1	7	122	0.69	20.96	32.8
72	INT7396	Regulation of Localization of GNRH1	1	81	0.62	6.57	31.31
73	INT11361	Gene_expression of SERPINE1	9	183	0.78	136.45	27.97
74	INT7565	Transcription of Pomc	1	69	0.72	14.46	27.41
75	INT22764	Localization of Ptger2	1	81	0.64	24.38	26.77
76	INT5232	Negative_regulation of Enpep	2	56	0.57	3.25	26.7
77	INT3559	Negative_regulation of Localization of Gnrhr	1	73	0.58	18.89	26.41
78	INT2261	Gene_expression of Lhb	3	121	0.77	42.78	26.04
79	INT6115	Positive_regulation of Pigm	1	82	0.64	16.96	25.73
80	INT5948	Regulation of Il1b	1	44	0.60	22.8	25.4
81	INT18400	Localization of Glp1r	1	97	0.80	11.96	24.32
82	INT10349	Negative_regulation of Il1b	2	48	0.58	25.53	24.24
83	INT11303	Gene_expression of Avp	1	116	0.78	39.23	23.88
84	INT250	Regulation of GHRH	1	65	0.61	17.46	23.19
85	INT4612	Positive_regulation of Localization of CGA	3	64	0.64	8.51	22.39
86	INT11893	Positive_regulation of Ptger2	2	96	0.69	31.49	21.92
87	INT1512	Binding of Prl	6	73	0.48	26.22	20.63
88	INT28951	Negative_regulation of IGF1	1	133	0.59	75.77	18.9
89	INT5967	Negative_regulation of Il1a	1	51	0.57	27.09	18.24
90	INT30312	Binding of Pdyn	1	30	0.37	4.2	18.23
91	INT18660	Binding of Gnrhr	1	45	0.41	10.6	16.85
92	INT6110	Negative_regulation of Gene_expression of Ins1	1	83	0.56	60.59	16.07
93	INT11636	Positive_regulation of SERPINE1	1	85	0.69	68.73	14.8
94	INT8089	Binding of Gnrh1	1	47	0.48	10.04	13.99
95	INT17938	Binding of Cpe	1	28	0.48	11.17	13.62
96	INT12321	Binding of Nr3c2	2	19	0.46	5.44	13.46
97	INT14572	Binding of INS	3	205	0.48	175.43	13.38
98	INT27242	Gene_expression of PGR	1	153	0.75	98.77	12.79
99	INT11208	Gene_expression of Cpe	2	23	0.78	2.42	11.09
100	INT952	Negative_regulation of GHRH	2	57	0.56	25.3	10.34
101	INT20425	Localization of Cpe	1	23	0.81	5.18	9.14
102	INT3467	Positive_regulation of Ptger1	1	28	0.54	10.59	8.93
103	INT13739	Positive_regulation of Positive_regulation of Avp	1	18	0.70	4.78	8.2
104	INT2257	Localization of Gip	1	31	0.74	11.08	7.92
105	INT28358	Gene_expression of Nanog	1	25	0.70	3.52	7.85
106	INT50195	Positive_regulation of Positive_regulation of Il1b	1	12	0.67	7.41	7.64
107	INT3659	Negative_regulation of Gcg	1	26	0.51	10.08	7.39
108	INT9785	Negative_regulation of Positive_regulation of Gnrh1	1	18	0.43	1.88	7.35
109	INT6933	Gene_expression of ANTXRL	1	15	0.10	4.77	6.84
110	INT62691	Transcription of Cpe	2	11	0.40	3.5	6.66
111	INT24460	Localization of Drd2	1	12	0.73	2.96	6.46
112	INT9683	Binding of GH1	2	57	0.47	21.14	5.99
113	INT45275	Gene_expression of CSH1	2	39	0.62	9.39	5.85
114	INT1649	Localization of CSH1	2	15	0.46	3.65	5.75
115	INT4034	Negative_regulation of Gip	2	16	0.53	6.46	5.65
116	INT11360	Localization of SERPINE1	3	41	0.80	33.98	5.61
117	INT19900	Binding of GHRH	1	22	0.37	5.75	5
118	INT1634	Gene_expression of Gcg	1	25	0.75	14.98	4.42
119	INT11354	Regulation of Gene_expression of SERPINE1	2	11	0.61	8.66	4.42
120	INT57642	Gene_expression of PCSK1	7	26	0.76	5.09	4.28
121	INT11635	Positive_regulation of Gene_expression of SERPINE1	2	35	0.68	24.57	4.26
122	INT110348	Negative_regulation of Dpp4	1	28	0.46	22.39	4.12
123	INT1640	Regulation of Localization of CSH1	1	3	0.19	0	4.12
124	INT108086	Negative_regulation of AKR1C3	2	17	0.58	7.7	3.99
125	INT84852	Transcription of Nfkb1	1	12	0.67	4.28	3.84
126	INT20915	Positive_regulation of Gabrp	1	6	0.64	1.01	3.49
127	INT7224	Positive_regulation of Gene_expression of Lhb	1	18	0.45	10.22	3.4
128	INT29333	Positive_regulation of Enpep	1	8	0.70	3.22	3.25
129	INT20146	Localization of Tfpi	1	5	0.81	1.21	3.11
130	INT4186	Negative_regulation of Localization of Gip	1	7	0.53	2.11	2.98
131	INT132760	Gene_expression of Pgr	1	47	0.66	28.17	2.85
132	INT78146	Gene_expression of AKR1C3	3	24	0.77	5.71	2.77
133	INT10350	Negative_regulation of Regulation of Il1b	1	3	0.41	0.58	2.69
134	INT1643	Regulation of CSH1	1	10	0.26	2.45	2.53
135	INT10070	Negative_regulation of Fshb	3	13	0.42	3.48	2.5
136	INT22019	Regulation of GHR	2	9	0.62	2.56	2.39
137	INT6117	Gene_expression of Gmcl1	1	4	0.49	2.39	2.33
138	INT31796	Gene_expression of Enpep	2	5	0.65	0.42	2.32
139	INT9386	Transcription of Cpe	1	7	0.72	0.53	2.31
140	INT72109	Negative_regulation of Localization of Glp1r	1	8	0.59	0.8	2.3
141	INT132769	Negative_regulation of PRS	1	7	0.37	4.82	2.25
142	INT12622	Localization of LGALS1	2	9	0.78	0.55	2.19
143	INT1511	Negative_regulation of Binding of Prl	2	7	0.59	1.64	2.19
144	INT62512	Gene_expression of PRS	1	10	0.64	6.03	2.09
145	INT51316	Regulation of NR3C1	1	7	0.51	4.23	2.09
146	INT10071	Gene_expression of Chrne	2	5	0.06	0.6	2.06
147	INT59737	Negative_regulation of Glp1r	2	15	0.43	6.94	2.01
148	INT47062	Gene_expression of ANTXR1	1	10	0.66	4.63	1.93
149	INT85178	Gene_expression of OAS2	1	10	0.21	4.17	1.93
150	INT93886	Positive_regulation of Gene_expression of PGR	1	19	0.52	15.78	1.89
151	INT48722	Negative_regulation of Gene_expression of SERPINE1	1	12	0.43	7.66	1.85
152	INT62692	Localization of Nanog	1	3	0.73	0.82	1.85
153	INT81415	Gene_expression of Gabrp	1	2	0.30	1.49	1.84
154	INT36168	Regulation of Positive_regulation of Ptger2	1	5	0.45	0.19	1.76
155	INT92402	Negative_regulation of Transcription of Nfkb1	1	4	0.42	1.75	1.76
156	INT48720	Transcription of SERPINE1	2	11	0.68	4.76	1.67
157	INT89467	Gene_expression of Lhcgr	3	9	0.36	1.59	1.62
158	INT51984	Localization of Pcsk2	2	3	0.66	0.37	1.62
159	INT113279	Gene_expression of HSD17B2	2	3	0.24	3.65	1.59
160	INT132761	Negative_regulation of Pgr	1	6	0.50	3.07	1.58
161	INT28300	Gene_expression of GHR	1	10	0.78	4.29	1.5
162	INT10069	Negative_regulation of Lhb	1	2	0.49	0	1.36
163	INT47102	Regulation of Binding of GHRH	1	2	0.28	0	1.34
164	INT12621	Positive_regulation of Localization of LGALS1	2	2	0.08	0.07	1.17
165	INT32786	Localization of Enpep	1	4	0.68	0	1.16
166	INT10625	Regulation of Positive_regulation of Avp	1	4	0.44	1.06	1.04
167	INT31314	Positive_regulation of Negative_regulation of Enpep	1	3	0.35	0.18	1.02
168	INT132770	Positive_regulation of Gene_expression of HSD17B2	2	1	0.02	2.28	1.01
169	INT91035	Positive_regulation of HSD17B2	1	7	0.66	5.2	0.98
170	INT85733	Positive_regulation of Tpgs2	2	1	0.21	0.4	0.95
171	INT42258	Binding of Ubr4	3	1	0.40	0	0.9
172	INT99342	Positive_regulation of Gene_expression of Gabrp	1	2	0.23	0.76	0.87
173	INT73784	Regulation of Binding of GH1	1	2	0.26	0.82	0.86
174	INT48717	Positive_regulation of Localization of SERPINE1	2	6	0.66	2.64	0.83
175	INT1513	Regulation of Binding of Prl	1	4	0.45	0	0.81
176	INT51231	Regulation of Gene_expression of ANTXRL	1	1	0.01	0.1	0.81
177	INT47937	Positive_regulation of Gene_expression of ANTXR1	1	3	0.49	0.86	0.8
178	INT27546	Positive_regulation of Furin	1	4	0.40	0.49	0.75
179	INT27545	Gene_expression of Furin	1	6	0.63	0.75	0.74
180	INT4397	Transcription of CSH1	5	7	0.57	0.65	0.72
181	INT73783	Regulation of Gene_expression of GHR	1	1	0.45	0	0.7
182	INT70362	Transcription of GH1	3	9	0.56	2.01	0.69
183	INT132759	Positive_regulation of Gene_expression of Pgr	1	9	0.38	5.12	0.64
184	INT132768	Negative_regulation of Gene_expression of PRS	1	1	0.03	1.18	0.61
185	INT118585	Binding of PNN	1	6	0.25	2.47	0.56
186	INT47933	Positive_regulation of Localization of Drd2	1	1	0.10	0.23	0.56
187	INT47934	Negative_regulation of Localization of Drd2	1	1	0.10	0.22	0.56
188	INT132762	Gene_expression of Hsd17b2	1	1	0.06	1.21	0.55
189	INT132763	Positive_regulation of Gene_expression of Hsd17b2	1	1	0.04	1.21	0.55
190	INT29235	Negative_regulation of Localization of Tfpi	1	1	0.26	0	0.49
191	INT85734	Positive_regulation of Positive_regulation of Tpgs2	1	1	0.21	0.2	0.48
192	INT85732	Negative_regulation of Tpgs2	1	1	0.25	0.18	0.46
193	INT47935	Binding of Pitx3	1	1	0.06	0.18	0.44
194	INT53084	Gene_expression of PCSK2	8	13	0.78	3.98	0.43
195	INT70561	Regulation of ESRRB	1	4	0.27	1.03	0.42
196	INT89465	Positive_regulation of Gene_expression of Lhcgr	2	4	0.24	1.03	0.41
197	INT157431	Binding of Sf1	1	1	0.05	0.99	0.39
198	INT48721	Negative_regulation of Localization of SERPINE1	1	3	0.43	2.4	0.38
199	INT51232	Positive_regulation of Localization of CSH1	1	3	0.31	0.32	0.37
200	INT21304	Positive_regulation of Fshr	1	2	0.40	0.2	0.35