J:Mol. Cell. Neurosci.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 2 0.66 5.22 3.22
2 INT105101 Pdyn Regulation of Samd10 1 1 0.00 0 1.02
3 INT86150 Inhba Positive_regulation of Gene_expression of Calca 1 1 0.09 0.61 0.81
4 INT86151 Olr1745 Positive_regulation of Gene_expression of Calca 1 1 0.51 0.6 0.8
5 INT108671 Positive_regulation of ras Positive_regulation of Positive_regulation of Trpv1 1 1 0.04 0.26 0.76
6 INT113931 Mors1 Positive_regulation of Gtpbp4 1 1 0.02 0 0.67
7 INT113611 Binding of Pick1 and Grip2 1 1 0.31 0.6 0.63
8 INT113610 Binding of Nsf and Grip2 1 1 0.24 0.6 0.63
9 INT78627 Gdnf Negative_regulation of Negative_regulation of P2rx3 1 1 0.00 0.42 0.38
10 INT112596 Tgfb1 Negative_regulation of Negative_regulation of Mptp1 1 1 0.26 0.72 0.22
11 INT112595 Tgfb1 Negative_regulation of Gene_expression of Mptp1 1 1 0.27 0.72 0.22
12 INT108669 ras Negative_regulation of Positive_regulation of Trpv1 1 1 0.05 0.28 0.17
13 INT108665 Negative_regulation of Gtf3a Positive_regulation of Trpv1 1 1 0.06 0.28 0.17
14 INT108668 ras Regulation of Gene_expression of Trpv1 1 1 0.03 0.33 0.17
15 INT108662 Ntf3 Positive_regulation of Trpv1 1 1 0.17 0.28 0.17
16 INT108663 Lrpap1 Negative_regulation of Positive_regulation of Ephb1 1 1 0.11 0.28 0.17
17 INT108667 ras Negative_regulation of Positive_regulation of Ephb1 1 1 0.02 0.28 0.17
18 INT108664 Lrpap1 Negative_regulation of Positive_regulation of Trpv1 1 1 0.26 0.28 0.17
19 INT108672 Negative_regulation of Mdk Negative_regulation of Ntf3 Positive_regulation of Trpv1 1 1 0.01 0.28 0.17
20 INT108666 Gtf3a Positive_regulation of Trpv1 1 1 0.10 0.28 0.14
21 INT140771 Binding of NTN4 and Unc5a 1 1 0.02 0.35 0.07
22 INT140770 Binding of NTN4 and Unc5a 1 1 0.01 0.35 0.07
23 INT93174 Ttf1 Positive_regulation of GNRH1 1 1 0.04 0.07 0
24 INT93172 Ttf1 Negative_regulation of Transcription of Penk 1 1 0.01 0.07 0
25 INT93173 Ttf1 Positive_regulation of Erbb2 1 1 0.05 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT1912 Gene_expression of Calca 7 1152 0.78 453.25 739.84
2 INT3439 Localization of Abat 2 1017 0.78 112.39 727.06
3 INT58061 Gene_expression of Trpv1 4 1117 0.78 451.54 637.59
4 INT2543 Positive_regulation of Calca 3 787 0.70 331.13 592.08
5 INT64202 Positive_regulation of Trpv1 5 643 0.70 249.66 397.42
6 INT18357 Gene_expression of TRPV1 3 825 0.78 307.11 382.81
7 INT439 Localization of Gnrh1 11 976 0.81 100.96 363.25
8 INT2649 Regulation of Calca 1 433 0.62 146.05 330.95
9 INT5680 Gene_expression of Ngf 2 530 0.78 264.29 310.56
10 INT63932 Positive_regulation of Ephb1 4 537 0.70 259.67 296.14
11 INT5379 Gene_expression of Fos 1 656 0.78 255.5 292.54
12 INT97367 Gene_expression of Nav1 1 243 0.78 132.97 286.66
13 INT87687 Positive_regulation of Trpv1 1 409 0.70 210.24 257.59
14 INT11377 Positive_regulation of Ngf 1 331 0.70 206.5 238
15 INT5597 Gene_expression of Pdyn 2 433 0.78 62.97 235.47
16 INT1212 Binding of Oprl1 2 312 0.48 28.6 225.15
17 INT95787 Positive_regulation of Mapk1 18 568 0.70 226.51 220.94
18 INT16259 Positive_regulation of Bdnf 2 336 0.70 183.48 209.82
19 INT63934 Phosphorylation of Ephb1 1 377 0.82 150.52 188.66
20 INT6354 Localization of Gabrg1 1 321 0.74 41.41 186.74
21 INT4829 Positive_regulation of Localization of Abat 1 199 0.55 20.91 150.48
22 INT3300 Positive_regulation of Gene_expression of Calca 2 179 0.70 77.76 144.2
23 INT14843 Gene_expression of Gabrg1 1 301 0.77 62.63 139.16
24 INT5595 Positive_regulation of Pdyn 1 223 0.70 48.37 130.14
25 INT48923 Gene_expression of Ephb1 1 211 0.77 106.23 109.9
26 INT2159 Regulation of Localization of Gnrh1 5 200 0.62 13.28 99.07
27 INT7944 Positive_regulation of Fos 2 193 0.70 60.69 98.31
28 INT2122 Negative_regulation of Localization of Gnrh1 2 226 0.59 26.92 92.04
29 INT67682 Localization of Bdnf 1 204 0.81 72.36 88.92
30 INT96917 Positive_regulation of Mapk14 1 261 0.70 173.29 88.79
31 INT5594 Regulation of Pdyn 1 137 0.62 27.04 86.63
32 INT5780 Regulation of Gene_expression of Calca 1 90 0.62 59.52 85.03
33 INT4289 Positive_regulation of Localization of Gnrh1 3 202 0.70 12.3 84.01
34 INT92434 Phosphorylation of Mapk1 1 287 0.82 91.65 83.46
35 INT8534 Localization of Pax3 2 85 0.59 28.71 82.82
36 INT16254 Positive_regulation of Gene_expression of Ngf 1 144 0.70 80.61 82.08
37 INT12001 Regulation of Ngf 1 97 0.62 54.64 76.25
38 INT5593 Positive_regulation of Gene_expression of Pdyn 1 114 0.70 29.1 74.46
39 INT8962 Gene_expression of Cpe 1 110 0.71 39.67 71.67
40 INT2123 Positive_regulation of Gnrh1 1 209 0.70 24.2 68.97
41 INT6824 Regulation of Gene_expression of Pdyn 1 114 0.62 9.48 66.73
42 INT6176 Positive_regulation of Htr1a 1 117 0.67 28.23 66.17
43 INT83419 Gene_expression of Mors1 1 57 0.68 12.11 63.66
44 INT2056 Negative_regulation of Gnrh1 1 175 0.59 33.43 63.32
45 INT11318 Gene_expression of Gtf3a 1 274 0.52 183.82 60.89
46 INT7491 Localization of Pdyn 1 80 0.81 3.94 58.77
47 INT82055 Positive_regulation of Creb1 4 176 0.70 60.2 58.39
48 INT83602 Positive_regulation of Gene_expression of TRPV1 2 114 0.70 51.19 56.35
49 INT49436 Binding of TRPV1 2 145 0.48 38.35 55.08
50 INT6826 Transcription of Pdyn 1 130 0.71 22.19 54.88
51 INT117713 Phosphorylation of Akt1 1 275 0.82 95.82 54.34
52 INT7898 Gene_expression of Homer1 1 123 0.78 31.52 53.67
53 INT8700 Positive_regulation of Positive_regulation of Calca 1 56 0.67 21.69 53.66
54 INT66040 Positive_regulation of Bdnf 2 114 0.69 67.67 51.81
55 INT5957 Positive_regulation of Cpe 1 65 0.69 21.07 51.22
56 INT48920 Negative_regulation of Ephb1 1 107 0.57 43.6 51.02
57 INT8690 Localization of Tac1 1 71 0.80 22.98 50.75
58 INT40777 Positive_regulation of Akt1 1 163 0.69 59.41 49.43
59 INT49520 Gene_expression of P2rx3 6 121 0.78 61.15 49.24
60 INT66029 Negative_regulation of Tnf 1 100 0.59 84.28 48.16
61 INT47683 Negative_regulation of Bdnf 2 92 0.59 47.53 43.55
62 INT27798 Gene_expression of Ntrk2 1 111 0.78 56.08 42.68
63 INT102611 Negative_regulation of Positive_regulation of Mapk1 1 74 0.58 35.57 39.37
64 INT48933 Gene_expression of Mapk3 1 93 0.75 44.39 37.92
65 INT80075 Regulation of Gene_expression of Trpv1 1 55 0.62 32.42 36.88
66 INT70437 Negative_regulation of Mdk 1 115 0.57 41.03 35.72
67 INT103262 Localization of Nav1 1 53 0.81 19.23 34.44
68 INT96624 Positive_regulation of Positive_regulation of Trpv1 2 62 0.70 20.5 34.28
69 INT48924 Positive_regulation of Mapk3 1 107 0.67 50.53 34.05
70 INT5868 Positive_regulation of GNRH1 1 122 0.69 20.96 32.8
71 INT48890 Gene_expression of Gdnf 1 91 0.77 28.62 31.49
72 INT8531 Transcription of PDYN 1 56 0.72 19.51 30.99
73 INT29477 Transcription of Oprl1 4 52 0.72 5.05 30.52
74 INT46833 Positive_regulation of SGSM3 2 56 0.67 24.49 30.31
75 INT72375 Phosphorylation of Mapk3 1 87 0.80 43.66 30.27
76 INT7412 Positive_regulation of SST 1 71 0.70 24.44 29.48
77 INT6765 Localization of Oprl1 1 49 0.81 5.11 28.87
78 INT48202 Gene_expression of Tgfb1 4 146 0.78 89.93 27.76
79 INT112707 Negative_regulation of Akt1 2 89 0.59 28.85 27.76
80 INT21687 Positive_regulation of ras 2 143 0.58 97.34 27.31
81 INT85395 Gene_expression of Scn11a 4 62 0.78 17.97 26.89
82 INT127499 Positive_regulation of TRPA1 1 72 0.70 21.7 26.86
83 INT86062 Positive_regulation of Tnfrsf1a 1 51 0.69 40.69 26.2
84 INT95788 Positive_regulation of Positive_regulation of Mapk1 7 83 0.69 24.75 25.84
85 INT28336 Positive_regulation of Pax3 1 37 0.33 20.94 25.66
86 INT57874 Gene_expression of Egr1 1 113 0.78 68.46 24.95
87 INT96557 Binding of Bdnf 1 46 0.47 21.74 24.26
88 INT113925 Localization of Bdnf 3 59 0.79 24.03 22.76
89 INT102112 Gene_expression of Prnp 2 440 0.78 209.32 22.5
90 INT5096 Positive_regulation of Gtf3a 1 79 0.60 42.26 20.62
91 INT96511 Negative_regulation of Positive_regulation of Trpv1 1 35 0.59 10.95 19.79
92 INT30312 Binding of Pdyn 1 30 0.37 4.2 18.23
93 INT78233 Positive_regulation of P2rx3 1 36 0.56 21.49 17.25
94 INT49263 Binding of Grip2 1 31 0.41 9.86 16.38
95 INT8530 Transcription of Penk 1 48 0.70 11.67 16.34
96 INT124371 Negative_regulation of Gsk3b 2 170 0.55 87.92 15.51
97 INT69652 Regulation of P2rx3 2 26 0.61 17.17 15.4
98 INT26729 Negative_regulation of Drd2 1 28 0.55 9.32 15.17
99 INT69311 Gene_expression of Scn10a 6 31 0.78 15.54 14.64
100 INT111529 Phosphorylation of Mapk3 1 41 0.80 21.14 13.72
101 INT21421 Regulation of Gtpbp4 2 15 0.30 2.7 13.49
102 INT146053 Positive_regulation of Gpr65 1 2 0.61 12.11 13.38
103 INT69569 Positive_regulation of Prnp 1 175 0.70 96.31 13.34
104 INT70556 Positive_regulation of Localization of Pax3 1 9 0.34 3.13 12.11
105 INT83894 Positive_regulation of TRPM8 1 37 0.70 18.28 11.7
106 INT48203 Positive_regulation of Tgfb1 3 67 0.70 41.31 11.07
107 INT11479 Positive_regulation of KCNMA1 1 30 0.68 10.07 10.82
108 INT78579 Negative_regulation of P2rx3 2 23 0.59 10.13 10.78
109 INT87451 Positive_regulation of Mapk3 3 34 0.67 12.82 10.38
110 INT67915 Negative_regulation of Gtpbp4 2 18 0.33 6.31 10.17
111 INT59352 Positive_regulation of Fosb 2 16 0.58 1.89 10.09
112 INT15242 Regulation of Gene_expression of Homer1 1 14 0.62 4.33 9.28
113 INT119098 Positive_regulation of TRPV3 3 20 0.68 10.12 9.01
114 INT120967 Negative_regulation of Phosphorylation of Akt1 1 47 0.57 23.67 8.98
115 INT67116 Gene_expression of Ntrk3 1 20 0.59 7.64 8.94
116 INT121987 Phosphorylation of Grin1 1 11 0.80 4.73 8.88
117 INT68434 Gene_expression of Gtpbp4 1 15 0.54 5.5 7.91
118 INT72372 Positive_regulation of Phosphorylation of Mapk3 1 30 0.67 13.6 7.69
119 INT9785 Negative_regulation of Positive_regulation of Gnrh1 1 18 0.43 1.88 7.35
120 INT116619 Positive_regulation of Positive_regulation of Creb1 2 25 0.69 8.32 7.3
121 INT146055 Gene_expression of Gpr68 1 3 0.63 8.12 6.99
122 INT8532 Regulation of Transcription of PDYN 1 10 0.44 4.97 6.95
123 INT61120 Positive_regulation of Gene_expression of Tgfb1 3 34 0.70 21.15 6.93
124 INT101965 Positive_regulation of Kcnj9 1 8 0.31 1.64 6.87
125 INT18460 Positive_regulation of Transcription of PDYN 2 11 0.67 2.14 6.61
126 INT49883 Gene_expression of NPBWR1 5 9 0.77 3.66 6.32
127 INT79737 Positive_regulation of Ntrk1 1 12 0.49 3.98 6.24
128 INT62611 Phosphorylation of Ngf 1 13 0.82 1.12 5.8
129 INT32458 Gene_expression of VWF 1 57 0.78 28.97 5.56
130 INT69572 Localization of Prnp 3 96 0.81 38.11 5.45
131 INT75250 Negative_regulation of Positive_regulation of SGSM3 1 5 0.57 2.47 5.24
132 INT67868 Negative_regulation of Gene_expression of Tgfb1 2 18 0.43 14.27 5.16
133 INT20064 Regulation of Gene_expression of Cpe 1 9 0.47 2.05 5.16
134 INT78626 Regulation of Gdnf 1 7 0.45 3.3 4.64
135 INT47451 Positive_regulation of Positive_regulation of ras 1 18 0.35 10.07 4.6
136 INT75627 Gene_expression of Mapt 1 41 0.75 22.1 4.58
137 INT75629 Gene_expression of Mtap2 1 41 0.66 8.19 4.51
138 INT117936 Regulation of Gene_expression of Egr1 1 18 0.60 9.37 4.45
139 INT69570 Binding of Prnp 1 75 0.48 44.26 4.37
140 INT100125 Negative_regulation of Accn3 1 11 0.59 5.85 4.32
141 INT113926 Positive_regulation of Localization of Bdnf 1 7 0.56 3.15 4.25
142 INT63840 Positive_regulation of Positive_regulation of Gabrg1 1 9 0.49 0.9 4.11
143 INT69681 Negative_regulation of Tgfb1 1 42 0.51 22.28 4
144 INT113924 Binding of Mapk1 1 27 0.38 8.64 3.84
145 INT78625 Regulation of Gene_expression of Gdnf 1 7 0.37 2.5 3.47
146 INT132888 Negative_regulation of Phosphorylation of Grin1 1 3 0.57 1.18 3.43
147 INT94100 Regulation of Rgs4 1 6 0.62 0.61 3.41
148 INT113929 Negative_regulation of Kcnj9 3 4 0.30 0 3.11
149 INT5648 Negative_regulation of Mptp1 1 7 0.37 6.64 3.08
150 INT132887 Positive_regulation of Phosphorylation of Grin1 1 3 0.49 1.73 3.08
151 INT136891 Negative_regulation of TRPA1 1 7 0.43 2.45 3.06
152 INT62610 Phosphorylation of Ntrk1 2 5 0.56 1.64 2.68
153 INT105454 Transcription of Rgs4 1 6 0.53 0.45 2.63
154 INT25962 Gene_expression of COX8A 1 25 0.75 20.04 2.62
155 INT86147 Positive_regulation of Inhba 1 8 0.63 1.94 2.39
156 INT105453 Negative_regulation of Rgs4 2 6 0.59 0.85 2.3
157 INT123851 Positive_regulation of Gene_expression of NPBWR1 3 1 0.69 1.52 2.25
158 INT96467 Gene_expression of Lamb1 1 3 0.10 2.56 2.23
159 INT113608 Positive_regulation of Nsf 1 2 0.39 1.03 2.22
160 INT146058 Positive_regulation of Gpr132 1 2 0.48 2.26 1.95
161 INT146057 Positive_regulation of Gpr4 1 2 0.60 2.26 1.95
162 INT68857 Positive_regulation of Rxfp2 1 5 0.34 1.51 1.86
163 INT107477 Positive_regulation of Phosphorylation of Ntrk1 2 3 0.30 0.88 1.86
164 INT105100 Gene_expression of Samd10 2 1 0.00 0 1.76
165 INT49882 Positive_regulation of NPBWR1 1 5 0.67 0.89 1.56
166 INT132886 Negative_regulation of Positive_regulation of Mapk3 1 2 0.30 1.27 1.49
167 INT146054 Positive_regulation of Gpr68 1 2 0.57 2 1.44
168 INT113621 Gene_expression of Rgs4 4 5 0.75 1.7 1.41
169 INT112314 Regulation of Binding of Bdnf 1 3 0.38 0.61 1.34
170 INT26786 Positive_regulation of Uchl1 1 7 0.34 1.37 1.32
171 INT109211 Gene_expression of Slc5a3 1 3 0.41 0.66 1.3
172 INT113928 Positive_regulation of Negative_regulation of Kcnj9 1 1 0.28 0 1.24
173 INT93168 Gene_expression of Ttf1 6 24 0.63 17.18 1.14
174 INT113607 Positive_regulation of Pick1 1 1 0.48 0.82 1.13
175 INT59156 Binding of Sclt1 2 2 0.28 0.36 1.1
176 INT89628 Gene_expression of TAG 1 5 0.75 0.68 1
177 INT125960 Gene_expression of Ptprs 2 8 0.78 2.87 0.99
178 INT146056 Localization of Prelid1 1 1 0.03 1.36 0.98
179 INT113614 Gene_expression of Rgs3 3 1 0.76 1.26 0.9
180 INT36355 Gene_expression of Mptp1 1 3 0.39 3.01 0.88
181 INT115176 Positive_regulation of Phosphorylation of Ngf 1 3 0.47 0.4 0.87
182 INT24537 Gene_expression of Pmp2 1 2 0.58 0.97 0.86
183 INT136634 Transcription of Prnp 2 9 0.72 3.34 0.83
184 INT111485 Gene_expression of Pcna 1 2 0.75 0 0.83
185 INT117427 Gene_expression of Parn 1 1 0.44 1.18 0.79
186 INT97782 Protein_catabolism of Ephb1 3 5 0.86 1.27 0.76
187 INT86149 Localization of Smad1 1 2 0.56 1.29 0.76
188 INT130611 Positive_regulation of Vipr2 1 2 0.18 0.26 0.75
189 INT96466 Negative_regulation of Lamb1 1 1 0.01 0.54 0.75
190 INT97505 Gene_expression of Prrxl1 1 6 0.78 0.71 0.71
191 INT69571 Positive_regulation of Positive_regulation of Prnp 1 6 0.70 5.88 0.67
192 INT117935 Negative_regulation of SRA1 1 6 0.11 2.63 0.66
193 INT113623 Regulation of Rxfp2 2 3 0.13 0.84 0.65
194 INT130610 Positive_regulation of Positive_regulation of Vipr2 1 1 0.10 0.26 0.61
195 INT113624 Regulation of Rgs3 2 1 0.44 0.86 0.6
196 INT113617 Positive_regulation of Regulation of Rxfp2 2 1 0.23 0.86 0.6
197 INT123850 Negative_regulation of NPBWR1 1 1 0.43 0.46 0.6
198 INT113616 Negative_regulation of Rgs3 2 1 0.42 0.85 0.59
199 INT125966 Gene_expression of Sclt1 2 1 0.55 0.17 0.56
200 INT111484 Positive_regulation of Gene_expression of Pcna 1 1 0.67 0 0.54
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