J:Mol Pain

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT324068 Binding of GCH1 and SNRNP70 1 32 0.01 28.19 40.6
2 INT106676 Binding of Trpv1 and Phax 18 5 0.34 4.19 12.36
3 INT206768 TP53 Positive_regulation of Ltp 2 9 0.01 5.83 10.21
4 INT77646 Binding of Ngf and Ntrk1 23 3 0.40 7.85 9.26
5 INT106559 Binding of Bdnf and Ntrk2 23 6 0.43 11.09 7.33
6 INT251170 Clu Positive_regulation of Trpv1 1 11 0.28 2.61 6.49
7 INT88279 Ngf Positive_regulation of Ntrk1 5 4 0.76 3.06 5.23
8 INT351352 Binding of Trpv1 and Lpar1 1 6 0.21 5.86 4.62
9 INT296484 Binding of Gria2 and GRIP1 1 10 0.04 4.52 4.59
10 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 2 0.55 2.97 4.23
11 INT143270 Binding of Cnr1 and Gprasp1 4 1 0.54 0.64 4.18
12 INT136514 Binding of Grm1 and Grm5 4 1 0.12 1.8 3.9
13 INT130625 Prkcg Regulation of Prkaca 1 1 0.23 1.32 3.87
14 INT317511 Ppp1r9b Regulation of Oprm1 3 1 0.27 0.33 3.85
15 INT249566 Binding of Oprd1 and Psmd1 1 3 0.01 0.82 3.8
16 INT132862 Ngf Positive_regulation of Bdnf 4 1 0.46 4.05 3.65
17 INT322411 Hist1h1t Positive_regulation of Positive_regulation of OPRM1 1 3 0.00 1.25 3.63
18 INT302118 Binding of Oprm1 and Ppp1r9b 2 2 0.24 0.26 3.45
19 INT195931 Binding of OPRM1 and Trpv1 1 3 0.07 0.87 3.43
20 INT276678 Nkx1-1 Regulation of Nav1 1 2 0.15 0.88 3.31
21 INT276676 Prkcg Regulation of Nav1 1 2 0.30 0.82 3.29
22 INT354207 Igfbp7 Positive_regulation of Accn3 1 11 0.52 6.55 3.24
23 INT166134 Binding of Cxcl12 and Cxcr4 3 1 0.49 5.69 3.17
24 INT251146 Binding of Grin1 and Dlg2 1 3 0.36 1.95 3.16
25 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 2 0.65 3.74 3.11
26 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 2 0.41 0.62 3.11
27 INT276679 Prkcg Positive_regulation of Positive_regulation of Nkx1-1 1 2 0.07 0.94 3.08
28 INT102284 Binding of Grin1 and Grin2a 5 1 0.27 1.79 3.01
29 INT113234 Binding of Pax3 and Tacr1 3 2 0.12 1.54 2.93
30 INT264929 Binding of Cnr1 and Gnaz 1 3 0.18 1.71 2.89
31 INT221746 Ngf Positive_regulation of Ntrk1 1 2 0.02 0.92 2.88
32 INT298456 Prkaca Positive_regulation of Phosphorylation of Adarb1 1 2 0.00 1.86 2.85
33 INT351349 Prkcg Positive_regulation of Binding of Lpar1 1 2 0.15 2 2.82
34 INT170367 Binding of Grin1 and Grin2a 5 1 0.23 1.72 2.79
35 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 4 0.02 0.44 2.79
36 INT318474 Positive_regulation of OPRM1 Positive_regulation of Localization of CA2 1 2 0.17 0.55 2.7
37 INT182564 Binding of Ptger2 and Trpv1 1 3 0.18 1.77 2.67
38 INT150455 Binding of Prss12 and Nts 3 3 0.24 1.42 2.66
39 INT150457 Binding of Sort1 and Prss12 3 3 0.21 1.36 2.64
40 INT251150 Binding of Nos1 and Dlg2 1 2 0.30 1.98 2.62
41 INT223866 Ltp Positive_regulation of Positive_regulation of Mapk1 2 3 0.46 0.75 2.61
42 INT121742 Prkcg Positive_regulation of Ephb1 3 1 0.49 0.99 2.6
43 INT210696 Trpv1 Regulation of Slc12a2 1 2 0.25 1.97 2.58
44 INT128044 Bdnf Positive_regulation of Ephb1 2 1 0.31 1.89 2.57
45 INT356289 Binding of Egfr and Egf 1 4 0.13 3.02 2.52
46 INT107322 Positive_regulation of TRPV1 Positive_regulation of Localization of IL8 3 1 0.13 1.64 2.5
47 INT249567 Positive_regulation of Binding of Oprd1 and Psmd1 1 2 0.01 0.66 2.5
48 INT287746 Anxa1 Positive_regulation of Gene_expression of Lpar1 1 8 0.07 1.72 2.46
49 INT231968 Binding of Cpn1 and Rvm 1 3 0.11 1.57 2.45
50 INT231970 Binding of Cpn1 and Pag1 1 3 0.07 1.56 2.44
51 INT251147 Binding of Grin2b and Dlg2 1 6 0.33 2.75 2.43
52 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 1 0.59 2.72 2.42
53 INT121746 Prkaca Positive_regulation of Ephb1 2 1 0.23 0.92 2.35
54 INT322410 Hist1h1t Positive_regulation of Phosphorylation of OPRM1 1 3 0.00 0.08 2.31
55 INT314205 Ngf Positive_regulation of Phosphorylation of Mapk14 1 2 0.43 1.24 2.3
56 INT247601 Binding of PEPD and SCN9A 1 2 0.15 2.26 2.27
57 INT211748 Binding of Pag1 and Mors1 2 1 0.07 0.2 2.26
58 INT231971 Binding of Cpn1 and Shbdp1 1 3 0.04 1.39 2.26
59 INT228454 Ngf Positive_regulation of Phosphorylation of Trpv1 1 2 0.39 2.97 2.26
60 INT231967 Binding of Psmd1 and Cpn1 1 3 0.06 1.39 2.25
61 INT231969 Binding of Cfp and Cpn1 1 3 0.05 1.38 2.25
62 INT251164 Binding of Clu and Trpv1 1 4 0.19 0.44 2.23
63 INT197379 Tbs1 Positive_regulation of Ltp 6 1 0.07 1.87 2.21
64 INT142527 Binding of Slc1a2 and Slc1a3 2 1 0.31 0.12 2.13
65 INT318473 Positive_regulation of OPRM1 Positive_regulation of CA2 1 2 0.17 0.46 2.13
66 INT344386 Efnb1 Positive_regulation of Phosphorylation of Ephb2 1 2 0.15 2.85 2.13
67 INT351380 Ngf Regulation of TPM1 1 2 0.44 2.17 2.11
68 INT251145 Binding of Grin2a and Dlg2 1 5 0.31 2.3 2.11
69 INT281084 Prkaca Positive_regulation of Mapk1 2 1 0.25 0 2.06
70 INT240658 Ngf Positive_regulation of Ngf Positive_regulation of Bdnf 1 1 0.33 1.67 1.99
71 INT264928 Binding of Cnr1 and Hrh1 1 2 0.01 1.61 1.92
72 INT186435 Prkcg Regulation of Creb1 1 2 0.44 0.45 1.9
73 INT186432 Prkaca Regulation of Creb1 1 2 0.14 0.45 1.9
74 INT169570 Binding of ROS1 and TRPV1 3 6 0.33 3.07 1.89
75 INT297488 Itpr3 Regulation of Positive_regulation of Ltp 1 2 0.02 0.47 1.87
76 INT211747 Negative_regulation of Binding of Oprm1 and Mors1 1 2 0.09 0 1.86
77 INT112517 Binding of Ephb1 and Prkaca 3 1 0.18 0.58 1.85
78 INT276668 Ngf Regulation of Nav1 1 1 0.09 0.98 1.85
79 INT314210 Ngf Regulation of Phosphorylation of Mapk14 1 2 0.34 0.85 1.84
80 INT352464 Gse1 Positive_regulation of Gene_expression of Slc1a3 1 2 0.05 1.55 1.83
81 INT276669 Negative_regulation of Prkcg Regulation of Nav1 1 1 0.21 0.68 1.82
82 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 1 0.48 1.04 1.81
83 INT334343 GRP Regulation of Binding of GRP and Helt 1 2 0.02 0 1.81
84 INT276674 Negative_regulation of Nkx1-1 Regulation of Nav1 1 1 0.11 0.68 1.81
85 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 1 0.30 1.36 1.8
86 INT150456 Binding of Sort1 and Nts 3 3 0.45 0.64 1.79
87 INT334345 Binding of GRP and Helt 1 2 0.02 0 1.79
88 INT211746 Binding of Oprm1 and Mors1 1 2 0.08 0 1.78
89 INT276863 Gpr65 Regulation of Trpv1 1 2 0.25 1.78 1.75
90 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 1 0.04 0.73 1.75
91 INT253895 Binding of Htr1b and Htr1d 1 1 0.40 0.52 1.74
92 INT182565 Ptger2 Regulation of Trpv1 1 3 0.25 1.34 1.73
93 INT139156 Binding of Gria1 and Gria2 1 3 0.23 0.64 1.72
94 INT186433 Trib3 Regulation of Phosphorylation of Creb1 1 2 0.03 0.32 1.71
95 INT264922 Binding of Cnr1 and Mors1 1 1 0.14 0.1 1.71
96 INT45306 Pomc Positive_regulation of ENG 2 2 0.07 1.11 1.68
97 INT324067 Regulation of Binding of GCH1 and SNRNP70 1 1 0.01 0.95 1.67
98 INT276672 Binding of Prkcg and Nav1 1 1 0.16 0.18 1.67
99 INT276680 Binding of Prkcg and Nkx1-1 1 1 0.05 0.18 1.66
100 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 3 0.01 0 1.65
101 INT297489 Ryr2 Regulation of Positive_regulation of Ltp 1 2 0.05 0.16 1.64
102 INT354210 Binding of Igfbp7 and Accn3 1 6 0.27 3.91 1.64
103 INT182563 Ptger2 Positive_regulation of Ptger1 1 2 0.22 1.4 1.64
104 INT335405 Binding of Arntl and Npas2 1 2 0.28 1.82 1.61
105 INT276670 Binding of Trpv1 and Nkx1-1 1 1 0.07 0.68 1.6
106 INT195930 OPRM1 Regulation of Prkaca 1 1 0.01 0 1.59
107 INT136034 Edn1 Regulation of Trpv1 2 2 0.66 0.39 1.58
108 INT314214 Mapk14 Positive_regulation of Ngf 1 1 0.43 1.97 1.56
109 INT208991 Binding of CALM1 and Ca2 10 1 0.06 1.34 1.55
110 INT276671 Prkcg Positive_regulation of Nav1 1 1 0.23 0.21 1.55
111 INT209087 Crh Positive_regulation of Ceacam3 1 1 0.24 1.45 1.54
112 INT274943 Positive_regulation of Ltp Positive_regulation of Positive_regulation of Tac2 1 1 0.04 0.49 1.53
113 INT351366 LPA Positive_regulation of Rab38 1 1 0.00 0.95 1.53
114 INT334347 GRP Positive_regulation of Localization of Gabrg1 1 2 0.19 0 1.5
115 INT190772 Il4 Negative_regulation of Gene_expression of Ptger2 1 1 0.03 1.28 1.49
116 INT211744 Binding of Gopc and Mors1 1 1 0.10 0.2 1.48
117 INT276687 Pax3 Positive_regulation of Nkx1-1 1 1 0.00 0.59 1.47
118 INT276688 Positive_regulation of Prkcg Positive_regulation of Nkx1-1 Regulation of Trpv1 1 1 0.05 0.16 1.46
119 INT276675 Binding of Nkx1-1 and Nav1 1 1 0.09 0.21 1.46
120 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 1 0.06 1.26 1.45
121 INT276681 Calca Regulation of Nav1 1 1 0.07 0.74 1.45
122 INT276686 Calca Regulation of Nav1 1 1 0.26 0.74 1.45
123 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 1 0.06 1.26 1.45
124 INT121226 Ngf Regulation of Gene_expression of Trpv1 2 1 0.62 0.7 1.44
125 INT256299 Binding of Efnb1 and Ephb1 1 1 0.02 1.22 1.42
126 INT298458 Binding of Calcrl and Adarb1 1 2 0.00 0.23 1.41
127 INT78974 Binding of Prkcg and Prkaca 2 1 0.31 0.35 1.4
128 INT190775 Gene_expression of Il4 Negative_regulation of Positive_regulation of FOSL1 1 1 0.39 2.42 1.4
129 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 1 0.24 0.4 1.39
130 INT262568 Prkaca Regulation of Trpv1 2 1 0.10 0.65 1.38
131 INT182558 Binding of Ptgir and Trpv1 1 2 0.16 1.12 1.37
132 INT276673 Nkx1-1 Regulation of Trpv1 1 1 0.05 0.16 1.37
133 INT279165 Calca Regulation of Gene_expression of Fdft1 1 1 0.02 0.41 1.37
134 INT326194 Bdnf Regulation of Slc12a5 1 1 0.05 0.85 1.35
135 INT185330 Binding of Hrh1 and Tac1 1 1 0.00 0.1 1.34
136 INT298455 Calca Positive_regulation of Gene_expression of Ceacam3 1 1 0.17 0.47 1.34
137 INT314213 Mapk14 Positive_regulation of Agtrap 1 1 0.04 1.15 1.34
138 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 1 0.42 1.86 1.34
139 INT249565 Binding of Gabrg1 and Oprd1 1 1 0.00 0.1 1.33
140 INT300864 Ngf Positive_regulation of Mapk14 2 1 0.60 1.38 1.32
141 INT314211 Ngf Positive_regulation of Gene_expression of Agtrap 1 1 0.04 1.15 1.3
142 INT195929 Binding of OPRM1 and Prkaca 1 1 0.02 0.33 1.27
143 INT314209 Ngf Positive_regulation of Binding of Mapk14 1 1 0.43 1.48 1.27
144 INT343949 SERPINE2 Positive_regulation of Positive_regulation of Slco1c1 1 1 0.00 0.59 1.27
145 INT195541 Lct Positive_regulation of Gene_expression of Grm2 1 4 0.02 0.4 1.27
146 INT287104 Binding of Ntrk2 and T 1 5 0.20 3.29 1.26
147 INT211743 Positive_regulation of Binding of Pag1 and Mors1 1 1 0.09 0.1 1.25
148 INT271602 Binding of Pdgfa and Pdgfrl 1 2 0.02 0.86 1.25
149 INT342165 Binding of Aqp1 and Nav1 1 1 0.25 0.57 1.25
150 INT251142 Binding of Dlg4 and Grin2a 3 1 0.30 0.5 1.24
151 INT314198 Mapk14 Positive_regulation of Gene_expression of Trpv1 1 1 0.48 1.09 1.24
152 INT314212 Mapk14 Positive_regulation of Gene_expression of Agtrap 1 1 0.06 1.09 1.24
153 INT195926 Prkaca Positive_regulation of Trpv1 1 1 0.10 0.44 1.24
154 INT20530 Nts Regulation of Prss12 5 1 0.24 0.74 1.23
155 INT247924 Slc12a5 Regulation of Gene_expression of Slc12a2 1 1 0.25 1.43 1.23
156 INT274948 Binding of Dh and Ltp 1 1 0.11 0.55 1.23
157 INT247926 Slc12a5 Regulation of Cl 1 1 0.01 1.43 1.23
158 INT247925 Slc12a2 Regulation of Cl 1 1 0.01 1.44 1.23
159 INT256298 Binding of Creb1 and Ephb1 1 1 0.16 1.27 1.22
160 INT197231 Grik1 Regulation of Gabrg1 1 1 0.19 0.13 1.22
161 INT351379 Ngf Positive_regulation of Binding of Ngf and Ntrk1 1 1 0.38 0.63 1.21
162 INT112105 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2b 2 1 0.40 0.89 1.2
163 INT334351 Bdnf Regulation of Positive_regulation of Ephb1 1 1 0.18 1.27 1.2
164 INT281077 Binding of Gria2 and Gria3 2 3 0.24 0.35 1.19
165 INT298454 Prkcg Positive_regulation of Phosphorylation of Adarb1 1 1 0.00 0.41 1.19
166 INT256297 Binding of Creb1 and Insrr 1 1 0.00 1.22 1.19
167 INT256295 Binding of Creb1 and Grin2b 1 1 0.11 1.21 1.19
168 INT351373 Ngf Positive_regulation of Gene_expression of Ntrk1 1 1 0.35 0.41 1.18
169 INT314196 Ngf Positive_regulation of Tnf 1 2 0.50 1.98 1.18
170 INT351378 Gene_expression of Ngf Positive_regulation of Ntrk1 1 1 0.35 0.41 1.18
171 INT261617 SNRNP70 Regulation of Comt 1 1 0.01 0.4 1.18
172 INT351377 Gene_expression of Ngf Positive_regulation of Gene_expression of Ntrk1 1 1 0.35 0.41 1.18
173 INT85780 Prkaca Regulation of Prkcg 1 1 0.29 0.47 1.17
174 INT207116 F2 Positive_regulation of F2r 5 3 0.12 2.16 1.16
175 INT287749 Dmbx1 Positive_regulation of Gene_expression of Lpar1 1 2 0.41 0.82 1.16
176 INT335435 Ngf Positive_regulation of Ltb4r 1 1 0.52 1.06 1.16
177 INT189017 Binding of Pax3 and Lmna 1 1 0.14 0.42 1.16
178 INT206766 Positive_regulation of Ltp Positive_regulation of Positive_regulation of Nkx1-1 1 1 0.01 0.22 1.16
179 INT299985 BDKRB2 Regulation of Gene_expression of BDKRB1 1 1 0.21 0.75 1.16
180 INT314206 Mapk14 Positive_regulation of Pax3 1 1 0.08 0.67 1.15
181 INT326665 Cpe Positive_regulation of Oprd1 1 1 0.01 1.24 1.15
182 INT338053 F2r Positive_regulation of Localization of Calca 1 2 0.06 0.47 1.15
183 INT264930 Gnaz Positive_regulation of Negative_regulation of Cnr1 1 1 0.20 0 1.14
184 INT190771 Gene_expression of Il4 Negative_regulation of Gene_expression of Mapk14 1 1 0.15 1.14 1.13
185 INT190770 Il4 Negative_regulation of Gene_expression of Mapk14 1 1 0.20 1.14 1.13
186 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 1 0.25 1.3 1.12
187 INT222516 Binding of Calcrl and Ramp1 5 1 0.17 0.11 1.12
188 INT187805 Ms18 Regulation of Positive_regulation of Slc1a3 1 1 0.26 0.87 1.12
189 INT332776 FSCN1 Positive_regulation of Grin1 1 1 0.02 0.21 1.12
190 INT182550 Ptger1 Negative_regulation of Trpv1 1 2 0.35 0.73 1.12
191 INT346986 Binding of SHC3 and PAG1 1 1 0.35 1.02 1.12
192 INT264931 Binding of Gnaz and Hrh1 1 1 0.01 0.83 1.12
193 INT269190 Positive_regulation of Ephb1 Positive_regulation of Ceacam3 1 1 0.03 0.66 1.12
194 INT285659 Binding of Faah and Mgll 1 1 0.15 0.99 1.11
195 INT296950 Tacr1 Negative_regulation of Gene_expression of Cck 1 1 0.30 0.94 1.11
196 INT209088 Binding of Ceacam3 and Crhr1 1 1 0.34 1.26 1.11
197 INT193328 Grid1 Regulation of Positive_regulation of Prkcg 1 1 0.00 0.1 1.1
198 INT269191 Binding of Grin1 and Grin3a 2 1 0.32 1.05 1.09
199 INT269189 Binding of Grin2a and Grin3a 2 1 0.25 1.05 1.09
200 INT269200 Prkaca Positive_regulation of Phosphorylation of Ceacam3 1 1 0.03 0.65 1.09

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 45 3083 0.78 894.43 1639.02
2 INT2542 Localization of Calca 114 2008 0.81 518.3 1408.65
3 INT796 Gene_expression of Penk 23 1902 0.78 275.47 1057.59
4 INT6483 Gene_expression of TNF 51 3152 0.78 2515.62 929.82
5 INT6483 Gene_expression of TNF 2 3152 0.78 2515.62 929.82
6 INT7114 Positive_regulation of Ltp 252 1192 0.62 290.76 755.77
7 INT1912 Gene_expression of Calca 75 1152 0.78 453.25 739.84
8 INT3439 Localization of Abat 28 1017 0.78 112.39 727.06
9 INT5202 Positive_regulation of Gene_expression of Fos 21 1163 0.70 319.28 684
10 INT292 Localization of Penk 3 876 0.81 88.44 669.14
11 INT58061 Gene_expression of Trpv1 239 1117 0.78 451.54 637.59
12 INT728 Positive_regulation of Penk 7 1068 0.70 186.9 636.87
13 INT2543 Positive_regulation of Calca 33 787 0.70 331.13 592.08
14 INT797 Regulation of Penk 1 812 0.62 111.13 542.24
15 INT5228 Positive_regulation of Fos 33 934 0.70 209.8 503.87
16 INT50058 Negative_regulation of Cpox 2 907 0.58 426.28 428.29
17 INT9238 Gene_expression of IL6 3 1575 0.78 1135.66 424.22
18 INT4758 Positive_regulation of Localization of Calca 27 557 0.70 138.55 411.04
19 INT5895 Gene_expression of Oprm1 14 525 0.78 120.67 407.29
20 INT64202 Positive_regulation of Trpv1 135 643 0.70 249.66 397.42
21 INT467 Gene_expression of POMC 1 1048 0.78 332.8 394.16
22 INT1395 Negative_regulation of Penk 3 537 0.59 87.33 389.81
23 INT6056 Negative_regulation of Gene_expression of Fos 4 601 0.59 193.05 386.84
24 INT76660 Gene_expression of Trpv1 300 691 0.78 329.46 386.42
25 INT2540 Negative_regulation of Calca 22 538 0.59 172.11 384.38
26 INT18357 Gene_expression of TRPV1 2 825 0.78 307.11 382.81
27 INT18357 Gene_expression of TRPV1 57 825 0.78 307.11 382.81
28 INT287 Localization of Cck 1 518 0.81 86.84 364.04
29 INT439 Localization of Gnrh1 1 976 0.81 100.96 363.25
30 INT5660 Binding of Oprd1 3 477 0.48 71.86 342.06
31 INT16260 Gene_expression of Bdnf 61 671 0.78 283.44 339.1
32 INT5235 Negative_regulation of TNF 12 924 0.59 772.91 331.98
33 INT2649 Regulation of Calca 8 433 0.62 146.05 330.95
34 INT5059 Positive_regulation of TNF 10 1050 0.70 896.51 322.81
35 INT5979 Gene_expression of Oprd1 5 428 0.78 75.64 320.32
36 INT34869 Negative_regulation of PTGS2 1 778 0.59 366.76 319.85
37 INT5540 Positive_regulation of Oprm1 7 344 0.70 76.77 319.71
38 INT5680 Gene_expression of Ngf 19 530 0.78 264.29 310.56
39 INT46460 Gene_expression of NAV1 78 288 0.78 135.51 305.75
40 INT4941 Positive_regulation of Oprd1 3 345 0.70 74.26 304.41
41 INT9131 Positive_regulation of Prkcg 83 431 0.70 130.8 302.41
42 INT63932 Positive_regulation of Ephb1 123 537 0.70 259.67 296.14
43 INT886 Gene_expression of Pomc 10 676 0.78 129.87 295.98
44 INT11624 Gene_expression of OPRM1 87 445 0.78 72.36 294.36
45 INT5379 Gene_expression of Fos 62 656 0.78 255.5 292.54
46 INT3579 Localization of Oxt 7 555 0.81 43.35 292.44
47 INT97367 Gene_expression of Nav1 76 243 0.78 132.97 286.66
48 INT9158 Gene_expression of Tnf 8 722 0.78 522.01 277.68
49 INT2365 Positive_regulation of Cck 1 354 0.70 87.8 277.41
50 INT9381 Positive_regulation of TRPV1 1 523 0.70 187.4 276.05
51 INT9381 Positive_regulation of TRPV1 32 523 0.70 187.4 276.05
52 INT94450 Gene_expression of Nav1 124 359 0.78 131.85 275.46
53 INT6852 Localization of TNF 4 883 0.81 705.95 270.84
54 INT10832 Gene_expression of IL8 3 1050 0.78 698.72 270
55 INT5591 Regulation of Gene_expression of Fos 2 425 0.62 129.06 265.78
56 INT9659 Gene_expression of Il6 2 991 0.78 715.11 265.57
57 INT87687 Positive_regulation of Trpv1 137 409 0.70 210.24 257.59
58 INT16868 Gene_expression of Il6 6 807 0.78 499.48 256.57
59 INT2909 Positive_regulation of Abat 6 334 0.70 62.1 256.43
60 INT5501 Regulation of Oprd1 3 283 0.62 55.1 249.9
61 INT1005 Localization of Sst 1 385 0.81 26.31 244.56
62 INT1902 Gene_expression of Cck 3 348 0.78 70.33 241.92
63 INT11377 Positive_regulation of Ngf 26 331 0.70 206.5 238
64 INT1665 Positive_regulation of Pag1 13 270 0.68 186.63 229.87
65 INT4759 Negative_regulation of Localization of Calca 14 294 0.59 82.62 226.45
66 INT9987 Gene_expression of Abat 25 296 0.78 95.46 226.34
67 INT6406 Binding of Oprm1 4 280 0.48 40.54 226.26
68 INT11009 Phosphorylation of Creb1 55 458 0.82 111.34 221.97
69 INT626 Localization of CALCA 1 289 0.81 125.39 221.15
70 INT95787 Positive_regulation of Mapk1 135 568 0.70 226.51 220.94
71 INT6665 Gene_expression of FOS 6 520 0.77 165.31 217.66
72 INT6293 Gene_expression of Oprm1 1 312 0.78 48.73 215.61
73 INT4893 Gene_expression of Tacr1 58 366 0.78 129.67 213.92
74 INT22548 Positive_regulation of Casp3 1 483 0.70 258.78 213.07
75 INT6482 Positive_regulation of Gene_expression of TNF 5 659 0.70 569.88 210
76 INT16259 Positive_regulation of Bdnf 53 336 0.70 183.48 209.82
77 INT48955 Gene_expression of Nos2 1 753 0.78 403.87 208.08
78 INT2651 Positive_regulation of Pomc 3 403 0.70 95.72 206.24
79 INT9132 Negative_regulation of Prkcg 65 279 0.59 88.05 203.47
80 INT798 Positive_regulation of Gene_expression of Penk 9 394 0.70 78.53 203.07
81 INT11313 Positive_regulation of Il6 9 526 0.70 331.27 201.59
82 INT2211 Negative_regulation of Abat 5 267 0.59 66.51 200.98
83 INT63934 Phosphorylation of Ephb1 65 377 0.82 150.52 188.66
84 INT6354 Localization of Gabrg1 18 321 0.74 41.41 186.74
85 INT94952 Positive_regulation of Mapk14 67 305 0.70 197.83 186.61
86 INT1652 Regulation of Pomc 1 387 0.62 61.01 186.51
87 INT24326 Gene_expression of Ngf 20 346 0.78 218.67 184.71
88 INT10194 Positive_regulation of IL6 3 702 0.70 600.62 183.38
89 INT3440 Negative_regulation of Localization of Abat 4 221 0.57 33.94 180.36
90 INT12602 Negative_regulation of Oprm1 8 190 0.59 36.11 177.85
91 INT49441 Negative_regulation of Cpox 3 494 0.59 303.22 177.46
92 INT7506 Negative_regulation of Ltp 27 267 0.46 91.01 176.8
93 INT1429 Gene_expression of PDYN 3 308 0.78 61.33 175.65
94 INT19472 Gene_expression of Il1 17 554 0.76 419.75 175.35
95 INT943 Negative_regulation of Cck 1 205 0.59 38.42 174.78
96 INT26472 Regulation of Oprm1 7 191 0.62 35.84 173.1
97 INT5930 Positive_regulation of Oprm1 1 221 0.70 31.19 172.93
98 INT4937 Negative_regulation of Oprd1 7 224 0.59 44.51 171.11
99 INT438 Gene_expression of Crh 1 376 0.78 159.11 169.17
100 INT739 Negative_regulation of POMC 1 358 0.59 102.28 166.77
101 INT55879 Gene_expression of CCL2 3 421 0.78 240.74 166.02
102 INT4768 Positive_regulation of OPRM1 39 212 0.70 31.09 164.28
103 INT5513 Negative_regulation of Pomc 3 295 0.59 60.9 158.63
104 INT51921 Gene_expression of Cpox 3 501 0.73 229.81 157.81
105 INT66280 Gene_expression of Nos2 34 534 0.78 330.78 157.07
106 INT6042 Binding of Oprm1 4 248 0.48 31.77 154.34
107 INT4740 Gene_expression of Th 1 298 0.78 61.27 154.03
108 INT2910 Regulation of Abat 4 169 0.62 36.95 153.53
109 INT120811 Gene_expression of Gopc 84 1174 0.59 428.49 150.55
110 INT4829 Positive_regulation of Localization of Abat 2 199 0.55 20.91 150.48
111 INT49134 Gene_expression of Grin1 45 270 0.78 84.78 148.61
112 INT5050 Regulation of Localization of Calca 20 149 0.62 41.25 148.57
113 INT6108 Gene_expression of Npy 12 292 0.78 110.65 148.21
114 INT13353 Positive_regulation of Tnf 6 332 0.70 248.75 148.1
115 INT7628 Gene_expression of Ltp 44 273 0.77 70.21 147.87
116 INT1033 Positive_regulation of Ca2 42 507 0.68 131.76 147.64
117 INT3300 Positive_regulation of Gene_expression of Calca 6 179 0.70 77.76 144.2
118 INT2780 Regulation of Gene_expression of Penk 1 265 0.62 32.45 143.88
119 INT60694 Gene_expression of Il10 13 567 0.78 369.48 143.69
120 INT9660 Regulation of TNF 1 363 0.62 312.94 139.99
121 INT90910 Phosphorylation of Grin1 69 150 0.82 68.23 139.24
122 INT14843 Gene_expression of Gabrg1 16 301 0.77 62.63 139.16
123 INT48895 Gene_expression of Il10 14 333 0.78 221.2 138.52
124 INT4658 Binding of OPRM1 20 188 0.48 25.96 136.24
125 INT2541 Binding of Calca 10 200 0.48 67.14 134.62
126 INT60126 Regulation of Trpv1 41 186 0.62 85.53 133.4
127 INT11012 Positive_regulation of Creb1 21 258 0.70 84.4 132
128 INT5380 Positive_regulation of Gene_expression of Fos 23 243 0.70 105.65 131.05
129 INT64161 Positive_regulation of Prkca 19 213 0.70 85.06 129.91
130 INT115386 Gene_expression of Ppara 3 779 0.77 549.99 128.36
131 INT1614 Gene_expression of Oprl1 2 164 0.78 31.43 127.74
132 INT5842 Gene_expression of Gfap 45 372 0.78 153.71 127.71
133 INT5008 Localization of Calca 48 204 0.81 80.35 125.16
134 INT6323 Positive_regulation of Gabrg1 8 213 0.70 45.08 124.34
135 INT4824 Positive_regulation of Tacr1 22 169 0.70 66.1 123.46
136 INT4259 Positive_regulation of Npr1 2 262 0.70 49.37 123.11
137 INT7533 Gene_expression of Tlr4 19 720 0.78 343.22 121.57
138 INT14151 Gene_expression of Casp3 2 311 0.78 140.26 120.68
139 INT64201 Negative_regulation of Trpv1 33 203 0.59 79.18 119.75
140 INT2555 Positive_regulation of Localization of Penk 1 116 0.70 24.35 119.73
141 INT8243 Positive_regulation of Il6 1 451 0.70 358.24 119.28
142 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 103 1138 0.72 311.58 119.18
143 INT12501 Positive_regulation of Adarb1 10 166 0.58 36.94 118.92
144 INT5010 Gene_expression of Calca 28 197 0.78 85.76 118.75
145 INT9235 Negative_regulation of Gene_expression of TNF 10 346 0.59 252.98 118.61
146 INT7341 Positive_regulation of Grin1 13 169 0.70 65.86 118.38
147 INT12339 Localization of IL8 1 437 0.81 251.87 117.39
148 INT92669 Gene_expression of Bdnf 22 309 0.78 178.26 116.68
149 INT62124 Gene_expression of NOS1 19 444 0.78 218.08 114.85
150 INT48593 Positive_regulation of NOS1 8 420 0.68 226.15 114.71
151 INT170025 Gene_expression of Fig4 85 588 0.67 183.27 113.32
152 INT16253 Positive_regulation of Gene_expression of Bdnf 18 196 0.70 92.67 113.01
153 INT11011 Positive_regulation of Phosphorylation of Creb1 35 190 0.70 49.25 112.01
154 INT49651 Gene_expression of Creb1 18 276 0.78 114.77 111.96
155 INT48923 Gene_expression of Ephb1 54 211 0.77 106.23 109.9
156 INT65731 Gene_expression of Cnr1 40 234 0.78 63.82 109.34
157 INT11051 Positive_regulation of Gene_expression of IL6 2 415 0.69 319.21 109.3
158 INT5283 Positive_regulation of Npy 2 191 0.70 66.77 109.2
159 INT27096 Positive_regulation of Nfkb1 5 325 0.70 195.11 109.06
160 INT8413 Gene_expression of Ptgs1 2 248 0.78 110.17 108.58
161 INT47243 Gene_expression of Prkcg 20 195 0.78 58.05 108.44
162 INT4936 Localization of Tacr1 9 125 0.80 35.7 107.7
163 INT7627 Negative_regulation of Positive_regulation of Ltp 35 162 0.50 41.2 106.27
164 INT49171 Gene_expression of Nos1 1 241 0.78 140.7 104.76
165 INT49171 Gene_expression of Nos1 34 241 0.78 140.7 104.76
166 INT69440 Gene_expression of ROS1 27 752 0.78 477.64 103.83
167 INT90091 Gene_expression of GOPC 16 967 0.67 366.22 103.6
168 INT4742 Gene_expression of Tac1 22 177 0.78 69.99 102.66
169 INT89054 Positive_regulation of Gene_expression of Trpv1 35 156 0.70 90.78 102.03
170 INT10838 Positive_regulation of IL8 1 381 0.70 295.51 101.62
171 INT82878 Gene_expression of Ccl2 42 201 0.78 164.95 101.35
172 INT74826 Gene_expression of Slc1a2 73 131 0.78 61.83 100.84
173 INT97701 Phosphorylation of Mapk14 20 191 0.82 115.33 100.46
174 INT5587 Regulation of Fos 4 191 0.62 40.81 99.7
175 INT52651 Positive_regulation of Prkaca 53 136 0.67 40.82 99.16
176 INT1351 Gene_expression of Pag1 15 131 0.57 89.48 98.76
177 INT293 Protein_catabolism of Penk 1 161 1.00 11.71 98.45
178 INT7944 Positive_regulation of Fos 8 193 0.70 60.69 98.31
179 INT4822 Localization of Ca2 25 417 0.80 99.57 96.45
180 INT17459 Positive_regulation of Gene_expression of FOS 3 182 0.67 53.45 96.38
181 INT940 Negative_regulation of Ptgs1 1 219 0.59 104.34 95.97
182 INT74058 Gene_expression of Nos1 6 260 0.78 80.04 95.71
183 INT3537 Positive_regulation of Car2 1 413 0.56 103.51 94.35
184 INT3537 Positive_regulation of Car2 33 413 0.56 103.51 94.35
185 INT29971 Gene_expression of Oprk1 12 126 0.78 35.32 93.97
186 INT104000 Phosphorylation of Grin2b 49 73 0.82 48.34 93.48
187 INT18755 Positive_regulation of Rvm 28 79 0.60 60 92.93
188 INT81417 Gene_expression of PAG1 12 94 0.58 90.85 92.79
189 INT94953 Negative_regulation of Mapk14 12 156 0.59 104.77 91.51
190 INT69764 Positive_regulation of Cnr1 11 126 0.70 67.8 91.49
191 INT77435 Positive_regulation of Nos2 6 343 0.70 208.49 91.43
192 INT9516 Negative_regulation of Gabrg1 6 149 0.53 27.83 91.02
193 INT38731 Localization of Trpv1 28 138 0.81 52.73 90.49
194 INT1639 Negative_regulation of OPRM1 3 107 0.59 13.86 90.37
195 INT48767 Negative_regulation of NOS1 7 312 0.59 154.25 90.32
196 INT1160 Positive_regulation of Rbm39 23 122 0.57 28.19 90.28
197 INT6585 Positive_regulation of Insrr 16 110 0.52 40.67 89.9
198 INT74376 Gene_expression of Cnr1 4 173 0.78 73.43 89.7
199 INT18032 Positive_regulation of Oprk1 8 108 0.70 30.78 89.7
200 INT12763 Phosphorylation of Prkcg 39 167 0.82 38.91 89.63
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