J:Molecular Human Reproduction

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT175329 Binding of ICAM1 and ITGAL 14 4 0.18 10.06 2.81
2 INT260897 CRH Positive_regulation of Localization of IL8 1 3 0.24 0.09 1.51
3 INT260894 CRH Regulation of Localization of MMP3 1 2 0.21 0.36 0.85
4 INT260895 CRH Regulation of MMP1 1 2 0.11 0.31 0.74
5 INT260893 CRH Positive_regulation of Gene_expression of IL8 1 1 0.28 0.05 0.31
6 INT260896 CRH Positive_regulation of Localization of MMP9 1 1 0.15 0.15 0.3
7 INT294290 PROK1 Positive_regulation of Gene_expression of IL11 1 7 0.59 0.46 0.23
8 INT294292 PROK1 Regulation of IL11 1 6 0.53 0.42 0.17
9 INT294309 PROK1 Regulation of Gene_expression of IL11 1 10 0.53 0.25 0.15
10 INT260944 Mapk14 Positive_regulation of Transcription of Aqp3 1 1 0.29 0.21 0.09
11 INT260947 Mapk14 Positive_regulation of Aqp3 1 1 0.29 0.21 0.09
12 INT294272 PROK1 Positive_regulation of IL11 Positive_regulation of Gene_expression of NPEPPS 1 1 0.01 0.16 0.09
13 INT294295 PROK1 Positive_regulation of IL11 1 1 0.40 0.15 0.09
14 INT260945 Mapk14 Positive_regulation of Gene_expression of Aqp3 1 1 0.29 0.21 0.09
15 INT294289 IL11 Positive_regulation of Gene_expression of NPEPPS 1 1 0.01 0.06 0.09
16 INT294302 PROK1 Positive_regulation of Localization of IL11 1 3 0.40 0.36 0.08
17 INT294308 PROKR1 Regulation of Gene_expression of IL11 1 2 0.34 0 0.08
18 INT294315 PROK1 Regulation of PROKR1 1 2 0.24 0 0.08
19 INT294310 PTGER2 Positive_regulation of Gene_expression of IL11 1 1 0.06 0.12 0.08
20 INT284501 Positive_regulation of Binding of ICAM1 and ITGAL 1 2 0.06 0.2 0.07
21 INT284503 Binding of ICAM1 and ITGAM 1 2 0.05 0.2 0.07
22 INT284504 ITGAL Positive_regulation of Gene_expression of ITGAM 1 2 0.03 0.2 0.06
23 INT294291 PROK1 Regulation of Localization of IL11 1 2 0.53 0 0.05
24 INT294311 Gene_expression of RCAN1 Positive_regulation of IL11 1 2 0.39 0 0.04
25 INT294299 Gene_expression of RCAN1 Negative_regulation of PROK1 1 2 0.42 0 0.04
26 INT294298 PROK1 Positive_regulation of Gene_expression of RCAN1 1 1 0.49 0 0.03
27 INT260948 Khsrp Negative_regulation of Binding of Elavl1 1 1 0.24 0.11 0.03
28 INT294303 PTGER2 Positive_regulation of Localization of IL11 1 1 0.04 0.08 0.03
29 INT294293 Binding of RCAN1 and CABIN1 1 1 0.03 0 0.03
30 INT260946 Zfp36 Negative_regulation of Binding of Elavl1 1 1 0.21 0.11 0.03
31 INT294301 PTGER2 Positive_regulation of IL11 1 1 0.04 0.08 0.03
32 INT294305 PROK1 Regulation of RCAN1 1 1 0.26 0 0
33 INT294312 PROKR1 Positive_regulation of Gene_expression of IL11 1 1 0.38 0 0
34 INT294304 RCAN1 Negative_regulation of PROK1 1 1 0.57 0 0
35 INT294307 Gene_expression of RCAN1 Negative_regulation of Gene_expression of IL11 1 1 0.36 0.09 0
36 INT294306 Positive_regulation of PROK1 Positive_regulation of Transcription of IL11 1 1 0.40 0.08 0
37 INT294300 PROK1 Positive_regulation of Positive_regulation of IL11 1 1 0.40 0.15 0
38 INT294316 IL6ST Positive_regulation of Gene_expression of IL11 1 1 0.22 0 0
39 INT294314 Binding of IL11 and NFATC1 1 1 0.06 0 0
40 INT294361 PROK1 Regulation of Gene_expression of Il11 1 1 0.64 0.05 0
41 INT294313 Gene_expression of CABIN1 Positive_regulation of IL11 1 1 0.03 0.06 0
42 INT294296 Binding of IL11 and PROK1 1 1 0.32 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 1 3152 0.78 2515.62 929.82
2 INT9238 Gene_expression of IL6 2 1575 0.78 1135.66 424.22
3 INT10832 Gene_expression of IL8 12 1050 0.78 698.72 270
4 INT6482 Positive_regulation of Gene_expression of TNF 1 659 0.70 569.88 210
5 INT55879 Gene_expression of CCL2 6 421 0.78 240.74 166.02
6 INT120811 Gene_expression of Gopc 2 1174 0.59 428.49 150.55
7 INT7533 Gene_expression of Tlr4 1 720 0.78 343.22 121.57
8 INT12339 Localization of IL8 15 437 0.81 251.87 117.39
9 INT69440 Gene_expression of ROS1 7 752 0.78 477.64 103.83
10 INT90091 Gene_expression of GOPC 3 967 0.67 366.22 103.6
11 INT10838 Positive_regulation of IL8 2 381 0.70 295.51 101.62
12 INT77435 Positive_regulation of Nos2 1 343 0.70 208.49 91.43
13 INT96917 Positive_regulation of Mapk14 1 261 0.70 173.29 88.79
14 INT48408 Gene_expression of ICAM1 4 494 0.78 340.08 88.6
15 INT920 Localization of PLOD1 1 223 0.81 42.25 78.7
16 INT6656 Gene_expression of YY1 2 135 0.75 24.73 72.16
17 INT10837 Positive_regulation of Gene_expression of IL8 4 294 0.70 190.08 70.34
18 INT67981 Positive_regulation of CCL2 1 165 0.70 136.84 61.85
19 INT11318 Gene_expression of Gtf3a 1 274 0.52 183.82 60.89
20 INT73048 Gene_expression of MMP9 7 268 0.77 159.75 57.81
21 INT48232 Gene_expression of MMP1 13 245 0.78 96.31 57.72
22 INT96914 Phosphorylation of Mapk14 2 168 0.82 108.46 53.32
23 INT81498 Positive_regulation of Gene_expression of CCL2 4 107 0.70 53.89 45.22
24 INT170054 Negative_regulation of Gopc 1 280 0.38 117.89 42.4
25 INT3933 Positive_regulation of PLOD1 1 128 0.70 30.76 42.03
26 INT29496 Gene_expression of MMP3 10 136 0.75 49.49 41.78
27 INT5454 Localization of CRH 6 124 0.79 79.18 41.53
28 INT69437 Positive_regulation of ROS1 2 328 0.58 222.83 40.56
29 INT48222 Positive_regulation of Localization of IL8 2 123 0.59 78.04 37.2
30 INT133028 Gene_expression of TLR2 3 209 0.73 131.92 36.17
31 INT11325 Gene_expression of HLA-E 2 209 0.76 98.05 33.72
32 INT99610 Localization of MMP9 3 126 0.79 48.46 32.67
33 INT7082 Gene_expression of CRH 14 180 0.78 64.66 31.74
34 INT7975 Regulation of PLOD1 10 97 0.62 20.9 30.51
35 INT10915 Gene_expression of ITGAM 7 164 0.78 92.42 29.78
36 INT15610 Localization of GOPC 1 223 0.65 68.26 28.7
37 INT83708 Negative_regulation of MAPK1 1 156 0.57 84.93 27.85
38 INT1638 Negative_regulation of PLOD1 2 92 0.59 21.69 26.61
39 INT73047 Positive_regulation of MMP9 1 133 0.68 73.22 26.42
40 INT12124 Gene_expression of MAPK1 1 141 0.75 82.4 25.58
41 INT172458 Regulation of Gopc 2 155 0.53 62.57 24.86
42 INT6441 Positive_regulation of CRH 3 98 0.69 57.22 24.12
43 INT917 Positive_regulation of Localization of PLOD1 1 51 0.69 8.53 22.87
44 INT105021 Binding of GOPC 1 187 0.40 60.39 20.38
45 INT93663 Positive_regulation of MMP1 2 72 0.67 33.38 19.86
46 INT2216 Gene_expression of SELL 8 92 0.77 59.29 17.71
47 INT84464 Gene_expression of DPP4 3 101 0.78 56.15 17.53
48 INT10214 Gene_expression of VIM 1 153 0.78 115.88 16.29
49 INT26314 Positive_regulation of MMP3 4 48 0.67 22.14 16.17
50 INT7970 Gene_expression of PLOD1 5 120 0.71 44.42 15.54
51 INT171666 Regulation of GOPC 2 117 0.39 40.41 15.47
52 INT170855 Negative_regulation of GOPC 1 188 0.38 70.92 15.41
53 INT5333 Gene_expression of NPEPPS 2 45 0.65 26.34 15.25
54 INT81486 Localization of MMP3 11 31 0.81 12.94 15.21
55 INT103210 Localization of MMP1 13 43 0.78 12.15 15.13
56 INT74587 Gene_expression of MMP8 2 31 0.78 24.4 14.91
57 INT92823 Positive_regulation of Gene_expression of MMP1 1 65 0.68 25.69 14.31
58 INT37722 Gene_expression of NCAM1 1 103 0.75 81.57 14.18
59 INT171134 Gene_expression of CD28 4 67 0.65 32.55 13.61
60 INT5452 Regulation of CRH 1 56 0.62 15.32 12.42
61 INT11288 Negative_regulation of CRH 1 44 0.00 16.69 12.37
62 INT117113 Regulation of Mapk14 1 28 0.45 16.71 11.99
63 INT133030 Positive_regulation of Gene_expression of TLR2 1 53 0.65 38.15 10.65
64 INT94454 Gene_expression of CD68 1 73 0.72 63.94 10.43
65 INT95632 Positive_regulation of MMP8 1 26 0.70 10.06 9.96
66 INT6651 Localization of FPR1 1 18 0.73 3.27 9.9
67 INT80549 Binding of ICAM1 2 53 0.47 42.76 9.72
68 INT102987 Regulation of MMP3 3 23 0.60 9.35 9.54
69 INT63338 Regulation of Gene_expression of ICAM1 2 42 0.62 28.26 9.06
70 INT187190 Positive_regulation of Localization of MMP9 1 27 0.68 8.1 8.93
71 INT74520 Positive_regulation of CD68 1 30 0.61 31.68 7.59
72 INT121752 Gene_expression of IL11 33 54 0.62 18.05 7.16
73 INT170381 Transcription of Gopc 1 59 0.60 15.96 6.82
74 INT20922 Positive_regulation of Localization of CRH 1 18 0.67 11.12 6.79
75 INT64792 Positive_regulation of Gene_expression of ITGAM 7 39 0.69 23.21 6.71
76 INT10917 Positive_regulation of ITGAM 2 31 0.67 16.39 6.69
77 INT137206 Positive_regulation of TLR2 1 47 0.65 33.36 6.4
78 INT95607 Regulation of MMP1 2 19 0.60 7.86 6.18
79 INT61417 Gene_expression of ITGAL 4 36 0.75 29.62 6.15
80 INT74422 Regulation of Localization of IL8 1 21 0.62 10.19 5.99
81 INT57502 Positive_regulation of Gene_expression of CRH 1 30 0.70 23.37 5.7
82 INT64767 Negative_regulation of Gene_expression of HLA-E 1 18 0.57 12.64 5.23
83 INT24889 Negative_regulation of CABIN1 2 36 0.48 16.76 4.73
84 INT102237 Positive_regulation of Gene_expression of MMP3 1 22 0.44 7.77 4.71
85 INT56032 Positive_regulation of NCAM1 1 38 0.49 26.01 4.68
86 INT24278 Gene_expression of FUT4 2 33 0.75 26.7 4.29
87 INT202417 Gene_expression of Gata3 1 16 0.61 7.84 4.12
88 INT99608 Transcription of MMP9 1 18 0.65 9.67 4.11
89 INT174195 Negative_regulation of HLA-E 1 31 0.42 11.98 3.88
90 INT93110 Regulation of CDCP1 1 16 0.03 7.98 3.83
91 INT179826 Gene_expression of Il11 13 29 0.75 11.5 3.75
92 INT5320 Gene_expression of PTGFR 1 18 0.59 12.99 3.7
93 INT94431 Transcription of MMP1 3 14 0.56 4.1 3.66
94 INT173849 Positive_regulation of Localization of MMP3 1 7 0.49 4.6 3.65
95 INT13451 Positive_regulation of DPP4 1 23 0.68 9.33 3.62
96 INT201959 Positive_regulation of Gene_expression of DPP4 1 13 0.53 6.24 3.4
97 INT87517 Gene_expression of LDLR 2 73 0.69 37.35 3.32
98 INT170606 Regulation of Gene_expression of GOPC 1 31 0.37 6.08 3.31
99 INT25031 Negative_regulation of Gene_expression of PLOD1 1 14 0.54 3.86 2.89
100 INT15179 Positive_regulation of Gene_expression of SELL 3 18 0.61 14.35 2.84
101 INT101246 Gene_expression of Gata6 1 6 0.68 3.03 2.68
102 INT172186 Gene_expression of IL6ST 6 20 0.75 11.63 2.67
103 INT169987 Transcription of GOPC 1 45 0.60 21.88 2.61
104 INT151309 Positive_regulation of Positive_regulation of MMP3 1 5 0.60 2.62 2.5
105 INT172179 Positive_regulation of Gene_expression of IL11 7 7 0.55 4.29 2.43
106 INT32920 Gene_expression of Msx1 1 19 0.71 4.24 2.42
107 INT120124 Transcription of MMP3 1 9 0.69 2.15 2.38
108 INT61418 Positive_regulation of ITGAL 4 24 0.14 12.86 2.3
109 INT12033 Binding of PLOD1 1 15 0.48 8.04 2.3
110 INT27878 Gene_expression of FCGR1B 2 22 0.26 20.62 2.04
111 INT83709 Negative_regulation of Gene_expression of MAPK1 1 12 0.41 6.57 2.01
112 INT104564 Gene_expression of Aqp3 1 8 0.65 4.92 1.99
113 INT7974 Regulation of Gene_expression of PLOD1 1 6 0.42 0.41 1.99
114 INT20276 Positive_regulation of Abo 1 4 0.07 1.04 1.98
115 INT7972 Positive_regulation of Gene_expression of PLOD1 1 15 0.42 5.73 1.96
116 INT108393 Positive_regulation of Localization of MMP1 2 5 0.40 0.85 1.91
117 INT179830 Negative_regulation of Il11 2 5 0.41 2.87 1.87
118 INT24888 Gene_expression of CABIN1 3 3 0.56 0.91 1.71
119 INT149642 Binding of Elavl1 2 5 0.23 5.49 1.59
120 INT133422 Binding of IL6ST 2 10 0.40 4.9 1.49
121 INT189948 Gene_expression of Pttg1 1 106 0.76 104.68 1.41
122 INT69398 Regulation of Gene_expression of HLA-E 1 14 0.60 3.54 1.27
123 INT106423 Binding of IL11 3 6 0.37 2.16 1.27
124 INT126907 Positive_regulation of Gene_expression of CD68 2 8 0.42 10.94 1.23
125 INT141054 Binding of NFATC1 4 14 0.40 3.65 1.22
126 INT171041 Positive_regulation of IL11 10 5 0.55 2.49 1.22
127 INT75923 Positive_regulation of IL6ST 1 5 0.45 2.49 1.21
128 INT70673 Regulation of IL11 4 5 0.45 2.89 1.2
129 INT260901 Localization of Elavl1 1 2 0.47 8.78 1.18
130 INT168135 Localization of H3 1 10 0.30 4 1.15
131 INT179831 Negative_regulation of Gene_expression of Il11 3 6 0.41 1.92 1.14
132 INT82703 Transcription of LDLR 1 6 0.64 0.4 1.13
133 INT272438 Gene_expression of PROK1 10 32 0.63 15.06 1.01
134 INT260905 Phosphorylation of Khsrp 1 2 0.52 2.3 1
135 INT27883 Positive_regulation of FCGR1B 1 5 0.10 6.15 0.97
136 INT179823 Localization of Il11 9 13 0.78 2.18 0.95
137 INT260921 Negative_regulation of Khsrp 1 2 0.34 3.12 0.94
138 INT141058 Gene_expression of NFATC1 2 8 0.56 8.21 0.89
139 INT84933 Regulation of Gene_expression of SELL 1 8 0.39 5.62 0.84
140 INT147488 Gene_expression of Eef1a2 1 5 0.49 0.87 0.84
141 INT220937 Transcription of MMP8 2 2 0.22 0.09 0.81
142 INT171017 Localization of IL11 15 9 0.64 4.83 0.76
143 INT101411 Negative_regulation of IL11 3 4 0.43 1.16 0.75
144 INT141057 Positive_regulation of NFATC1 1 5 0.57 1.95 0.74
145 INT181016 Gene_expression of Plac8 1 4 0.46 5.45 0.72
146 INT130194 Positive_regulation of PROK1 5 9 0.65 0.97 0.7
147 INT289467 Transcription of IL11 4 6 0.57 1.5 0.67
148 INT260899 Regulation of Transcription of MMP8 1 1 0.13 0.09 0.62
149 INT185244 Gene_expression of Sox2 1 27 0.65 4.71 0.61
150 INT65977 Gene_expression of RCAN1 11 6 0.70 3.72 0.59
151 INT260906 Binding of Khsrp 1 2 0.30 1.48 0.57
152 INT141052 Transcription of NFATC1 1 5 0.44 1.34 0.49
153 INT133729 Positive_regulation of Gene_expression of ITGAL 5 8 0.49 2.96 0.48
154 INT226449 Negative_regulation of NFATC1 1 4 0.25 1.28 0.41
155 INT260917 Positive_regulation of Localization of Elavl1 1 2 0.32 4.1 0.41
156 INT219211 Positive_regulation of Gene_expression of NCAM1 2 5 0.49 2.82 0.4
157 INT36386 Positive_regulation of Gene_expression of FUT4 1 3 0.45 2.32 0.38
158 INT260916 Regulation of Elavl1 1 2 0.21 2.47 0.38
159 INT101024 Regulation of IL1RAPL1 1 2 0.01 0.63 0.38
160 INT141051 Phosphorylation of NFATC1 1 4 0.52 0.25 0.36
161 INT253069 Binding of PROK1 1 4 0.36 0.89 0.34
162 INT141056 Negative_regulation of Binding of NFATC1 1 2 0.35 0 0.31
163 INT179822 Binding of Il11 3 3 0.47 0.25 0.3
164 INT190451 Gene_expression of NANOG 1 33 0.59 3.28 0.29
165 INT260922 Gene_expression of Alox15 1 2 0.32 0.58 0.27
166 INT164210 Gene_expression of Cdx2 1 3 0.56 2.22 0.25
167 INT88004 Binding of CABIN1 1 2 0.03 0.11 0.25
168 INT260918 Regulation of Khsrp 1 2 0.28 1.33 0.25
169 INT61416 Positive_regulation of Positive_regulation of ITGAL 2 4 0.11 0.85 0.23
170 INT262469 Negative_regulation of Binding of PLOD1 1 1 0.14 0 0.2
171 INT260912 Positive_regulation of Gene_expression of Eef1a2 1 2 0.32 0.22 0.19
172 INT272432 Regulation of PROK1 4 2 0.42 1.16 0.18
173 INT284511 Gene_expression of ADAD2 1 1 0.05 0.17 0.18
174 INT272436 Negative_regulation of Gene_expression of PROK1 4 3 0.40 2.3 0.17
175 INT284438 Positive_regulation of Gene_expression of Il11 1 3 0.49 1.98 0.17
176 INT294326 Regulation of Positive_regulation of PROK1 2 1 0.42 0.3 0.17
177 INT294334 Regulation of Positive_regulation of IL11 2 1 0.36 0.3 0.17
178 INT179806 Positive_regulation of Localization of Il11 1 2 0.49 0 0.16
179 INT209992 Negative_regulation of Transcription of LDLR 1 2 0.29 0 0.16
180 INT87515 Negative_regulation of Gene_expression of LDLR 1 2 0.09 1.96 0.16
181 INT179833 Regulation of Gene_expression of Il11 2 2 0.44 0.08 0.15
182 INT294320 Positive_regulation of PROKR1 1 2 0.39 0.34 0.15
183 INT294354 Negative_regulation of Gene_expression of IL11 4 1 0.46 0 0.15
184 INT272430 Localization of PROK1 2 4 0.66 2.01 0.14
185 INT272434 Positive_regulation of Gene_expression of PROK1 5 2 0.47 0.86 0.14
186 INT260920 Gene_expression of Bmp15 1 1 0.42 0.15 0.14
187 INT292224 Localization of NFATC1 1 3 0.15 0.45 0.13
188 INT164520 Regulation of CABIN1 1 2 0.26 0.1 0.13
189 INT294341 Positive_regulation of Positive_regulation of IL11 2 1 0.55 0 0.13
190 INT294331 Positive_regulation of CABIN1 2 1 0.03 0 0.11
191 INT294338 Regulation of Regulation of IL11 1 1 0.21 0.2 0.1
192 INT294346 Positive_regulation of Gene_expression of RCAN1 8 1 0.63 0.34 0.09
193 INT294325 Binding of PROK2 1 1 0.21 0.27 0.09
194 INT294335 Positive_regulation of Positive_regulation of PROK1 1 1 0.47 0 0.09
195 INT260915 Transcription of Aqp3 1 1 0.67 0.21 0.09
196 INT274685 Localization of PROK2 1 3 0.42 0.31 0.08
197 INT294324 Positive_regulation of Transcription of NFATC1 1 1 0.09 0 0.08
198 INT294351 Regulation of Transcription of NFATC1 1 1 0.08 0 0.08
199 INT294337 Positive_regulation of Localization of NFATC1 1 1 0.13 0 0.08
200 INT260907 Phosphorylation of Zfp36 2 1 0.54 0.47 0.08
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