J:Naunyn Schmiedebergs Arch Pharmacol

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT328501 Sumo1 Negative_regulation of Gene_expression of Pglyrp1 1 1 0.00 1.54 0.83
2 INT328500 Sumo1 Positive_regulation of Negative_regulation of Cebpz 1 1 0.11 1.06 0.29
3 INT328499 Binding of Cebpz and Sumo1 1 1 0.08 0.84 0.27
4 INT328498 Sumo1 Positive_regulation of Plg 1 1 0.07 0.61 0.04
5 INT282799 Chrm2 Positive_regulation of Chrm3 1 1 0.16 0.29 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5540 Positive_regulation of Oprm1 1 344 0.70 76.77 319.71
2 INT886 Gene_expression of Pomc 1 676 0.78 129.87 295.98
3 INT9381 Positive_regulation of TRPV1 2 523 0.70 187.4 276.05
4 INT626 Localization of CALCA 11 289 0.81 125.39 221.15
5 INT22548 Positive_regulation of Casp3 2 483 0.70 258.78 213.07
6 INT120811 Gene_expression of Gopc 1 1174 0.59 428.49 150.55
7 INT2867 Gene_expression of CALCA 4 247 0.78 78.78 138.47
8 INT14151 Gene_expression of Casp3 2 311 0.78 140.26 120.68
9 INT8243 Positive_regulation of Il6 2 451 0.70 358.24 119.28
10 INT4860 Positive_regulation of CALCA 2 148 0.00 73.35 97.61
11 INT1760 Gene_expression of PTGER2 7 524 0.57 226.94 96.4
12 INT3537 Positive_regulation of Car2 2 413 0.56 103.51 94.35
13 INT11587 Gene_expression of CSF2 2 645 0.78 544.38 93.89
14 INT48767 Negative_regulation of NOS1 2 312 0.59 154.25 90.32
15 INT6585 Positive_regulation of Insrr 2 110 0.52 40.67 89.9
16 INT82448 Gene_expression of S100a8 1 246 0.77 236.72 84.02
17 INT56291 Gene_expression of Ros1 1 503 0.63 274.12 81.5
18 INT7344 Gene_expression of TAC1 1 132 0.75 35.48 68.26
19 INT4960 Positive_regulation of CSF2 3 285 0.70 256.73 65.73
20 INT6761 Binding of CALCA 1 100 0.48 26.71 62.05
21 INT8490 Negative_regulation of CALCA 2 87 0.59 29.73 51.34
22 INT19488 Localization of ABAT 14 56 0.69 21.51 50.56
23 INT9383 Localization of TRPV1 1 98 0.81 33.23 46.24
24 INT4776 Localization of TAC1 1 82 0.78 16.89 45.21
25 INT49552 Negative_regulation of Positive_regulation of Casp3 1 76 0.55 36.04 44.78
26 INT17561 Localization of Car2 2 303 0.79 60.95 44.52
27 INT11406 Positive_regulation of Localization of CALCA 1 49 0.70 20.64 42.8
28 INT9298 Positive_regulation of Gtpbp4 6 64 0.69 12.29 41.97
29 INT685 Regulation of AVP 1 124 0.62 34.9 39.91
30 INT6417 Negative_regulation of ABAT 1 49 0.51 19.6 36.81
31 INT11554 Negative_regulation of CSF2 4 129 0.59 108.55 29.44
32 INT133876 Positive_regulation of Gene_expression of Ros1 1 141 0.32 75.55 27.45
33 INT90313 Negative_regulation of Gene_expression of Casp3 2 57 0.57 22.23 26.77
34 INT1761 Positive_regulation of PTGER2 2 135 0.49 90.17 26.26
35 INT22549 Positive_regulation of Positive_regulation of Casp3 1 48 0.56 29.5 23.7
36 INT1764 Negative_regulation of Gene_expression of PTGER2 2 81 0.34 34.74 19.45
37 INT56749 Gene_expression of PCNA 1 219 0.77 111.25 18.42
38 INT35487 Localization of PTGER2 1 103 0.46 51.24 17.45
39 INT8571 Gene_expression of B3GAT1 1 54 0.75 36.85 15.98
40 INT171666 Regulation of GOPC 2 117 0.39 40.41 15.47
41 INT34952 Regulation of ABAT 1 28 0.61 6.05 14.39
42 INT82929 Gene_expression of Plat 1 58 0.78 26.96 13.85
43 INT11244 Transcription of CALCA 1 21 0.69 3.61 12.27
44 INT100821 Localization of Ros1 1 59 0.60 45.26 11.92
45 INT64225 Positive_regulation of Localization of ABAT 6 15 0.60 4.46 11.28
46 INT25170 Positive_regulation of Localization of Car2 1 78 0.67 15.25 11.24
47 INT1763 Regulation of Gene_expression of PTGER2 1 43 0.36 23.98 10.95
48 INT33099 Negative_regulation of INSRR 1 32 0.40 13.82 9.85
49 INT75137 Regulation of Akt1 1 74 0.48 37.89 9.7
50 INT102658 Negative_regulation of Gene_expression of CSF2 1 42 0.50 38.63 8.32
51 INT12859 Localization of Insrr 1 16 0.32 2.68 8.07
52 INT155989 Negative_regulation of Localization of ABAT 2 7 0.38 1.29 6.95
53 INT170381 Transcription of Gopc 1 59 0.60 15.96 6.82
54 INT155988 Regulation of Localization of ABAT 2 5 0.24 2.19 6.59
55 INT60692 Gene_expression of Pglyrp1 2 15 0.10 8.47 6.51
56 INT4561 Gene_expression of PLG 1 32 0.75 17.59 6.21
57 INT124825 Transcription of Plat 1 8 0.70 3.15 5.68
58 INT64888 Negative_regulation of HBM 1 52 0.16 34.33 5.45
59 INT148402 Gene_expression of Chrm2 2 95 0.54 24.25 5.27
60 INT74051 Negative_regulation of Localization of Car2 1 27 0.38 9.58 5.1
61 INT155138 Gene_expression of Phospho2 4 5 0.21 2.06 5.07
62 INT104668 Negative_regulation of Plat 1 27 0.49 17.18 4.83
63 INT16478 Positive_regulation of Plg 6 29 0.45 18.07 4.07
64 INT107415 Regulation of Kcnj9 1 6 0.62 1 3.87
65 INT86369 Positive_regulation of Gene_expression of PCNA 1 40 0.67 26.66 3.57
66 INT88852 Protein_catabolism of Casp3 1 28 0.65 23.57 2.74
67 INT148403 Positive_regulation of Chrm2 7 17 0.42 7.74 2.19
68 INT47543 Positive_regulation of Chrm3 3 11 0.38 5.23 2.17
69 INT17326 Binding of Plg 1 14 0.43 11.72 1.94
70 INT162533 Regulation of Lgals3 1 9 0.45 6.61 1.73
71 INT91868 Transcription of B4GALNT1 1 5 0.10 1.5 1.66
72 INT46640 Negative_regulation of Cebpz 2 9 0.37 2.67 1.52
73 INT165062 Negative_regulation of SLC29A4 2 1 0.59 0.29 1.5
74 INT155136 Negative_regulation of Phospho2 1 1 0.15 0.58 1.44
75 INT165061 Binding of SLC29A4 2 1 0.48 0.27 1.44
76 INT16388 Protein_catabolism of Plg 1 6 0.79 3.46 1.4
77 INT155137 Regulation of Gene_expression of Phospho2 1 1 0.10 0.53 1.31
78 INT199315 Binding of Plat 1 8 0.34 7.02 1.14
79 INT106960 Gene_expression of Chrm3 2 15 0.69 6.29 0.96
80 INT148401 Regulation of Chrm3 2 3 0.19 1.19 0.91
81 INT171851 Gene_expression of Sumo1 3 13 0.30 10.7 0.89
82 INT165060 Gene_expression of SLC29A4 1 1 0.68 0.19 0.81
83 INT227949 Negative_regulation of Chrm2 1 8 0.25 4.23 0.73
84 INT149689 Binding of Chrm3 3 3 0.24 1.54 0.65
85 INT193037 Regulation of Chrm2 1 7 0.19 8.82 0.64
86 INT171612 Gene_expression of Cebpz 2 5 0.58 2.61 0.62
87 INT104335 Localization of Chrm3 1 2 0.62 0.58 0.57
88 INT124487 Negative_regulation of Gene_expression of Plat 1 4 0.43 1.88 0.55
89 INT161266 Positive_regulation of Ripk1 1 1 0.49 0.09 0.47
90 INT164126 Negative_regulation of TRPM2 1 2 0.42 0 0.32
91 INT201347 Negative_regulation of Gene_expression of Chrm3 1 4 0.30 2.48 0.31
92 INT227952 Binding of Chrm2 4 9 0.19 5.19 0.25
93 INT254485 Regulation of Zmat3 1 2 0.00 0.75 0.24
94 INT164125 Binding of TRPM2 1 4 0.36 0.15 0.2
95 INT171849 Negative_regulation of Gene_expression of Sumo1 1 2 0.19 1.81 0.2
96 INT282798 Binding of Prkd1 1 2 0.18 2.11 0.19
97 INT228084 Localization of Chrm2 1 8 0.36 1.54 0.11
98 INT282797 Negative_regulation of Binding of Chrm2 1 1 0.19 0 0.05
99 INT328495 Positive_regulation of Binding of Plg 1 1 0.13 0.62 0.04
100 INT328496 Positive_regulation of Protein_catabolism of Plg 1 1 0.14 0.68 0.03
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