J:Neurochem. Res.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT2653 Slc3a1 Regulation of Penk 3 1 0.04 0.37 1.96
2 INT39950 Binding of ALB and PDYN 1 2 0.31 0 1.32
3 INT63308 Gypc Positive_regulation of Localization of Abat 1 2 0.11 0 0.83
4 INT147755 Binding of GNRH1 and TNF 1 2 0.32 2.37 0.79
5 INT71815 Coq10a Regulation of Oprd1 1 1 0.00 0.15 0.7
6 INT118138 Binding of Ca2 and Mgat4a 1 1 0.01 0 0.53
7 INT35167 Adrb2 Positive_regulation of Trh 1 1 0.05 0 0.45
8 INT5531 Binding of Acot1 and Chrna2 1 5 0.12 0 0.42
9 INT63307 Gypc Regulation of Localization of Abat 1 1 0.08 0 0.42
10 INT46225 Binding of ALB and POMC 1 1 0.36 0 0.4
11 INT46663 Guca2a Positive_regulation of Gucy2f 1 1 0.02 0 0.32
12 INT46664 GYPA Positive_regulation of Gucy2f 1 1 0.00 0 0.32
13 INT21886 Ptger2 Positive_regulation of C4orf6 1 1 0.01 0.19 0.25
14 INT5529 Acot1 Positive_regulation of Chrna2 1 1 0.17 0 0.09
15 INT5530 Positive_regulation of Binding of Acot1 and Chrna2 1 1 0.15 0 0.07

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 5 3083 0.78 894.43 1639.02
2 INT796 Gene_expression of Penk 2 1902 0.78 275.47 1057.59
3 INT6483 Gene_expression of TNF 2 3152 0.78 2515.62 929.82
4 INT3439 Localization of Abat 20 1017 0.78 112.39 727.06
5 INT5202 Positive_regulation of Gene_expression of Fos 4 1163 0.70 319.28 684
6 INT728 Positive_regulation of Penk 1 1068 0.70 186.9 636.87
7 INT797 Regulation of Penk 2 812 0.62 111.13 542.24
8 INT5228 Positive_regulation of Fos 3 934 0.70 209.8 503.87
9 INT443 Localization of POMC 1 1020 0.81 284.52 443.17
10 INT18357 Gene_expression of TRPV1 2 825 0.78 307.11 382.81
11 INT287 Localization of Cck 2 518 0.81 86.84 364.04
12 INT5660 Binding of Oprd1 5 477 0.48 71.86 342.06
13 INT876 Localization of Gh1 6 843 0.80 67.75 340.82
14 INT5979 Gene_expression of Oprd1 3 428 0.78 75.64 320.32
15 INT5540 Positive_regulation of Oprm1 1 344 0.70 76.77 319.71
16 INT4941 Positive_regulation of Oprd1 1 345 0.70 74.26 304.41
17 INT1352 Localization of Acot1 14 728 0.80 73.01 296.01
18 INT5379 Gene_expression of Fos 1 656 0.78 255.5 292.54
19 INT3579 Localization of Oxt 3 555 0.81 43.35 292.44
20 INT9381 Positive_regulation of TRPV1 2 523 0.70 187.4 276.05
21 INT94450 Gene_expression of Nav1 3 359 0.78 131.85 275.46
22 INT1396 Binding of Penk 11 355 0.48 22.79 269.65
23 INT5591 Regulation of Gene_expression of Fos 1 425 0.62 129.06 265.78
24 INT2909 Positive_regulation of Abat 1 334 0.70 62.1 256.43
25 INT3948 Regulation of Cck 1 291 0.62 58.07 255.88
26 INT5501 Regulation of Oprd1 2 283 0.62 55.1 249.9
27 INT1902 Gene_expression of Cck 1 348 0.78 70.33 241.92
28 INT11377 Positive_regulation of Ngf 1 331 0.70 206.5 238
29 INT5597 Gene_expression of Pdyn 3 433 0.78 62.97 235.47
30 INT1665 Positive_regulation of Pag1 1 270 0.68 186.63 229.87
31 INT9987 Gene_expression of Abat 3 296 0.78 95.46 226.34
32 INT6406 Binding of Oprm1 1 280 0.48 40.54 226.26
33 INT1212 Binding of Oprl1 3 312 0.48 28.6 225.15
34 INT6481 Binding of TNF 3 624 0.48 510.2 214.82
35 INT767 Localization of Gnrhr 2 565 0.80 106.68 214.57
36 INT22548 Positive_regulation of Casp3 7 483 0.70 258.78 213.07
37 INT48955 Gene_expression of Nos2 5 753 0.78 403.87 208.08
38 INT2651 Positive_regulation of Pomc 1 403 0.70 95.72 206.24
39 INT2211 Negative_regulation of Abat 1 267 0.59 66.51 200.98
40 INT50670 Gene_expression of CPOX 7 763 0.76 442.13 195.02
41 INT6354 Localization of Gabrg1 8 321 0.74 41.41 186.74
42 INT3440 Negative_regulation of Localization of Abat 4 221 0.57 33.94 180.36
43 INT943 Negative_regulation of Cck 1 205 0.59 38.42 174.78
44 INT5930 Positive_regulation of Oprm1 2 221 0.70 31.19 172.93
45 INT4937 Negative_regulation of Oprd1 1 224 0.59 44.51 171.11
46 INT2366 Binding of Cck 3 192 0.48 30.64 163.46
47 INT1303 Negative_regulation of Npr1 1 278 0.55 35.1 156.78
48 INT6042 Binding of Oprm1 1 248 0.48 31.77 154.34
49 INT880 Positive_regulation of Localization of Gh1 4 304 0.70 14.79 150.23
50 INT49134 Gene_expression of Grin1 1 270 0.78 84.78 148.61
51 INT1033 Positive_regulation of Ca2 1 507 0.68 131.76 147.64
52 INT1414 Regulation of Oprl1 1 169 0.62 32.05 139.99
53 INT11012 Positive_regulation of Creb1 2 258 0.70 84.4 132
54 INT48953 Positive_regulation of Nos2 3 486 0.70 239.85 131.87
55 INT5595 Positive_regulation of Pdyn 1 223 0.70 48.37 130.14
56 INT5842 Gene_expression of Gfap 2 372 0.78 153.71 127.71
57 INT695 Binding of POMC 6 304 0.48 56.66 126.85
58 INT6822 Gene_expression of Pdyn 1 215 0.78 35.99 125.76
59 INT6323 Positive_regulation of Gabrg1 1 213 0.70 45.08 124.34
60 INT4259 Positive_regulation of Npr1 1 262 0.70 49.37 123.11
61 INT14151 Gene_expression of Casp3 9 311 0.78 140.26 120.68
62 INT50674 Gene_expression of PTGS2 2 459 0.78 253.33 118.51
63 INT7341 Positive_regulation of Grin1 1 169 0.70 65.86 118.38
64 INT49651 Gene_expression of Creb1 1 276 0.78 114.77 111.96
65 INT5283 Positive_regulation of Npy 1 191 0.70 66.77 109.2
66 INT10272 Gene_expression of Il1b 1 194 0.78 121.02 103.03
67 INT5587 Regulation of Fos 1 191 0.62 40.81 99.7
68 INT1351 Gene_expression of Pag1 2 131 0.57 89.48 98.76
69 INT4822 Localization of Ca2 1 417 0.80 99.57 96.45
70 INT6437 Binding of YY1 1 154 0.47 26.3 90.46
71 INT6214 Negative_regulation of Adarb1 1 123 0.50 26.39 89.57
72 INT7885 Positive_regulation of Localization of Oxt 3 160 0.70 14.36 87.7
73 INT3441 Regulation of Localization of Abat 5 117 0.38 8.67 87.59
74 INT5594 Regulation of Pdyn 1 137 0.62 27.04 86.63
75 INT5610 Positive_regulation of Insr 2 140 0.69 37.26 86.24
76 INT2149 Positive_regulation of Oxt 1 181 0.70 24.8 85.43
77 INT875 Regulation of Localization of Gh1 4 166 0.62 12.87 84.97
78 INT2520 Negative_regulation of Ca2 4 271 0.57 72.13 83.71
79 INT8650 Gene_expression of Gal 3 152 0.78 61.97 81.72
80 INT6107 Localization of Npy 1 180 0.81 26.76 81.67
81 INT10534 Positive_regulation of Trib3 2 209 0.60 78.75 81.48
82 INT64636 Positive_regulation of Gene_expression of Nos2 2 242 0.70 147.52 79.53
83 INT1335 Negative_regulation of Oprl1 2 123 0.59 18.02 77.13
84 INT1353 Negative_regulation of Localization of Acot1 5 153 0.53 15.05 75.17
85 INT5593 Positive_regulation of Gene_expression of Pdyn 2 114 0.70 29.1 74.46
86 INT10274 Positive_regulation of Il1b 6 123 0.70 79.76 73.56
87 INT7028 Localization of Pdyn 2 90 0.81 8.89 73.54
88 INT79506 Gene_expression of Grin2b 2 122 0.78 43.71 73.42
89 INT3034 Localization of Ngf 2 126 0.81 50.81 72.84
90 INT1080 Negative_regulation of Ache 5 343 0.59 108.51 72.4
91 INT6490 Negative_regulation of ADCY1 1 145 0.58 26.25 70.96
92 INT1169 Negative_regulation of Bche 4 322 0.59 149.22 61.27
93 INT39153 Positive_regulation of PTGS2 1 182 0.70 96.16 60.6
94 INT546 Binding of ALB 6 311 0.48 85.98 60.14
95 INT50672 Positive_regulation of CPOX 1 205 0.44 125.93 60.06
96 INT1536 Negative_regulation of NA 1 244 0.55 52.67 59.79
97 INT62960 Gene_expression of P2rx2 1 149 0.77 58.31 59.16
98 INT7032 Positive_regulation of Pdyn 2 94 0.66 26.51 58.83
99 INT770 Regulation of Localization of Gnrhr 2 127 0.61 17.91 58.23
100 INT7340 Regulation of Grin1 2 87 0.62 30.37 57.93
101 INT2148 Negative_regulation of Oxt 1 105 0.59 11.42 57
102 INT1510 Binding of PDYN 5 94 0.48 4.68 56.44
103 INT1316 Positive_regulation of Acot1 1 129 0.60 18.86 56.13
104 INT1782 Regulation of Gh1 1 125 0.62 22 55.74
105 INT82650 Gene_expression of Bcl2 13 312 0.78 211.71 55.03
106 INT6826 Transcription of Pdyn 1 130 0.71 22.19 54.88
107 INT2276 Regulation of Ins1 1 234 0.61 103.78 54.05
108 INT49747 Transcription of Oprm1 3 68 0.72 9.01 53.78
109 INT4957 Negative_regulation of Grin1 1 87 0.59 24.51 53.21
110 INT1032 Regulation of Ca2 1 202 0.52 54.91 53.03
111 INT22546 Positive_regulation of Gene_expression of Casp3 5 97 0.70 47.89 51.92
112 INT5704 Binding of Slc3a1 1 78 0.43 8.52 51.78
113 INT5858 Positive_regulation of Drd1a 6 66 0.69 4.51 51.73
114 INT5338 Regulation of Npy 2 92 0.62 25.54 51.24
115 INT19488 Localization of ABAT 1 56 0.69 21.51 50.56
116 INT6796 Positive_regulation of Jun 1 165 0.70 37.18 49.64
117 INT2323 Gene_expression of Trh 1 146 0.78 29.92 49.5
118 INT49520 Gene_expression of P2rx3 1 121 0.78 61.15 49.24
119 INT16850 Negative_regulation of Localization of Gabrg1 4 73 0.51 8.28 47.89
120 INT51627 Gene_expression of Grin2a 3 82 0.76 25.09 47.6
121 INT374 Positive_regulation of Ldha 1 212 0.70 107.08 47.43
122 INT6544 Negative_regulation of Localization of Cck 1 67 0.59 8.05 47.23
123 INT873 Gene_expression of Gh1 1 130 0.76 26.15 46.75
124 INT5337 Negative_regulation of Npy 2 87 0.59 19.6 46.75
125 INT6823 Negative_regulation of Pdyn 6 68 0.58 13.95 46.12
126 INT49552 Negative_regulation of Positive_regulation of Casp3 2 76 0.55 36.04 44.78
127 INT88617 Positive_regulation of Gene_expression of Creb1 1 90 0.69 51.69 44.29
128 INT7828 Positive_regulation of Oprd1 4 55 0.69 14.11 42.86
129 INT9039 Negative_regulation of Htr1a 1 69 0.57 9.56 41.84
130 INT81251 Gene_expression of Trpv2 2 78 0.78 28.27 41.76
131 INT57442 Phosphorylation of Prkca 3 98 0.70 31.58 41.04
132 INT12228 Positive_regulation of Gene_expression of Abat 1 44 0.65 17.51 40.55
133 INT6357 Positive_regulation of Localization of Gabrg1 1 53 0.41 7.03 39.21
134 INT115 Negative_regulation of Maoa 2 65 0.59 16.27 38.66
135 INT11439 Positive_regulation of Csf2 1 105 0.69 62.63 37.77
136 INT5039 Positive_regulation of Gal 1 67 0.68 27.97 37.36
137 INT11246 Binding of Grin1 1 65 0.48 14.53 36.93
138 INT6417 Negative_regulation of ABAT 1 49 0.51 19.6 36.81
139 INT1354 Negative_regulation of Acot1 2 87 0.43 15.01 36.44
140 INT12029 Gene_expression of Car1 1 143 0.67 29.69 36.39
141 INT111052 Positive_regulation of Gene_expression of Nav1 2 44 0.70 18.98 35.28
142 INT6943 Positive_regulation of Gabrd 1 71 0.70 17.36 35.25
143 INT103262 Localization of Nav1 1 53 0.81 19.23 34.44
144 INT47710 Negative_regulation of GRIN1 1 71 0.57 25.57 34.24
145 INT1457 Negative_regulation of Binding of Penk 4 40 0.57 0.25 34.24
146 INT64171 Regulation of CPOX 2 109 0.36 55.36 32.96
147 INT1495 Positive_regulation of Rtcd1 2 91 0.54 22.93 32.43
148 INT12397 Gene_expression of Oprd1 1 53 0.78 9.1 31.31
149 INT1079 Positive_regulation of Ache 6 104 0.70 23.52 30.28
150 INT7664 Negative_regulation of Grip2 4 68 0.49 10.11 29.93
151 INT16769 Positive_regulation of Positive_regulation of Oprm1 1 31 0.57 8.29 29.66
152 INT4868 Gene_expression of GAL 1 75 0.78 22.23 29.02
153 INT6765 Localization of Oprl1 1 49 0.81 5.11 28.87
154 INT1616 Regulation of Gad1 1 46 0.61 10.2 28.64
155 INT93033 Negative_regulation of Grin2b 3 48 0.58 20.94 28.54
156 INT91775 Gene_expression of Slc6a4 1 102 0.78 26.45 28.23
157 INT1613 Binding of Nts 1 58 0.48 10.55 28.18
158 INT13290 Binding of Atxn2l 2 34 0.18 1.86 28.16
159 INT2650 Positive_regulation of Slc3a1 1 50 0.57 2.95 27.52
160 INT97 Negative_regulation of Adrb1 1 102 0.59 32.44 26.9
161 INT2569 Gene_expression of Ache 2 120 0.78 26.29 26.89
162 INT4735 Gene_expression of Acot1 1 80 0.71 13.22 26.68
163 INT6382 Regulation of Binding of Oprd1 1 36 0.61 7 26.48
164 INT605 Regulation of Acot1 1 61 0.62 10.7 26.34
165 INT276 Regulation of Ache 6 83 0.62 16.75 25.99
166 INT48832 Positive_regulation of Grip2 2 48 0.69 12.13 25.99
167 INT5426 Negative_regulation of RTCA 1 58 0.51 12.34 25.74
168 INT61664 Regulation of GRIN1 1 38 0.60 16.45 25.35
169 INT6385 Regulation of Man2a2 1 48 0.61 7.8 24.68
170 INT5690 Negative_regulation of Binding of Oprd1 1 36 0.59 8.29 24.52
171 INT100423 Gene_expression of Bax 12 141 0.75 98.43 24.48
172 INT22549 Positive_regulation of Positive_regulation of Casp3 2 48 0.56 29.5 23.7
173 INT47741 Negative_regulation of Flvcr2 1 43 0.51 5.72 23.37
174 INT2290 Protein_catabolism of POMC 1 41 0.99 4.86 23.36
175 INT20575 Gene_expression of Akr1d1 1 48 0.57 6.2 22.5
176 INT83797 Gene_expression of Bcl2l1 1 124 0.77 94.55 22.39
177 INT19949 Regulation of Positive_regulation of Fos 1 36 0.60 6.11 22.05
178 INT41230 Gene_expression of Nrm 1 16 0.67 6.37 21.67
179 INT10536 Gene_expression of Trib3 1 67 0.66 27.08 21.58
180 INT1334 Negative_regulation of Binding of Oprl1 1 29 0.59 3.03 20.62
181 INT1756 Negative_regulation of DNAH8 6 105 0.59 42.73 20.24
182 INT1278 Negative_regulation of Ldha 1 93 0.59 37.66 19.36
183 INT7680 Regulation of Drd1a 1 27 0.45 4.52 18.86
184 INT90612 Positive_regulation of Grin2a 2 33 0.65 15.11 18.84
185 INT5137 Binding of pCA 1 45 0.47 16.91 18.47
186 INT93734 Positive_regulation of Gene_expression of Bcl2 5 76 0.70 61.95 18.46
187 INT5533 Binding of Oxt 1 43 0.48 8.69 18.35
188 INT50420 Transcription of Grin1 1 30 0.71 13.21 18.28
189 INT2660 Negative_regulation of Fabp6 2 58 0.49 33.74 18.27
190 INT13244 Binding of Helt 3 30 0.31 4.56 18.01
191 INT21072 Localization of Adarb1 1 26 0.69 2.76 17.95
192 INT58495 Positive_regulation of Positive_regulation of Oprm1 1 22 0.49 2.44 17.66
193 INT6461 Gene_expression of Npr1 1 35 0.75 10.38 17.58
194 INT8037 Negative_regulation of Man2a2 1 39 0.42 5.15 17.44
195 INT86673 Positive_regulation of Bcl2 2 77 0.70 57.74 17.37
196 INT12875 Regulation of Adra2a 2 26 0.45 7.51 17.35
197 INT16624 Localization of Grin1 1 38 0.79 8.46 17.15
198 INT93037 Regulation of Grin2b 1 26 0.57 11.9 16.92
199 INT48690 Localization of Grip2 2 33 0.61 6.13 16.81
200 INT23657 Positive_regulation of APP 1 64 0.70 39.76 16.68
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