J:Neuron

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT104855 Prkaca Regulation of TRPV1 3 2 0.06 1.52 1.92
2 INT208731 Binding of pf and Cysltr1 1 5 0.02 1.74 0.87
3 INT350344 Gene_expression of Kcnn2 Negative_regulation of Positive_regulation of Ltp 1 2 0.10 0 0.79
4 INT261834 Itpr3 Positive_regulation of Prkca 2 1 0.01 0.33 0.78
5 INT350342 Tbp Positive_regulation of Ltp 1 2 0.25 0.48 0.64
6 INT153993 Myoz1 Regulation of TRPV1 1 1 0.00 0.46 0.44
7 INT153994 Regulation of Prkaca Regulation of TRPV1 1 1 0.02 0.46 0.44
8 INT153995 Regulation of Myoz1 Regulation of TRPV1 1 1 0.00 0.46 0.44
9 INT196881 Ly6 Positive_regulation of Prkca 2 1 0.01 0.25 0.42
10 INT208728 Positive_regulation of Dcn Positive_regulation of Cysltr1 1 1 0.02 0.3 0.24
11 INT208732 Dcn Positive_regulation of Cysltr1 1 1 0.02 0.29 0.24
12 INT350348 Binding of Car1 and Chrm1 1 1 0.09 0 0.2
13 INT208730 pf Positive_regulation of Cysltr1 1 1 0.02 0.38 0.19
14 INT273441 Binding of Vamp1 and Snap25 1 5 0.02 0.13 0.14
15 INT350343 Csnk2a2 Regulation of Grin1 1 2 0.11 0.09 0.11
16 INT350349 Binding of Chrm1 and Csnk2a2 1 1 0.11 0.09 0.09
17 INT350345 Tbp Positive_regulation of Positive_regulation of Grin1 1 1 0.18 0 0.07
18 INT273440 Positive_regulation of Binding of Vamp1 and Snap25 1 1 0.02 0.13 0.04
19 INT350347 Negative_regulation of Prkca Negative_regulation of Chrm1 1 1 0.08 0 0.03
20 INT350346 Negative_regulation of Prkca Negative_regulation of Negative_regulation of Chrm1 1 1 0.08 0 0.03
21 INT350341 Negative_regulation of Prkca Negative_regulation of Localization of Chrm1 1 1 0.08 0 0.03
22 INT308329 Binding of F5 and PTN 1 1 0.04 0 0
23 INT273443 Positive_regulation of Binding of Snap25 and Napa 1 1 0.05 0 0
24 INT273446 Binding of Vamp1 and Napa 1 2 0.02 0 0
25 INT273442 Binding of Snap25 and Napa 1 3 0.05 0 0
26 INT311764 Opn4 Regulation of Mrgprc1-ps 1 1 0.43 0 0
27 INT273449 Positive_regulation of Binding of Vamp1 and Napa 1 1 0.02 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT7114 Positive_regulation of Ltp 34 1192 0.62 290.76 755.77
2 INT4768 Positive_regulation of OPRM1 1 212 0.70 31.09 164.28
3 INT7628 Gene_expression of Ltp 11 273 0.77 70.21 147.87
4 INT1033 Positive_regulation of Ca2 1 507 0.68 131.76 147.64
5 INT64161 Positive_regulation of Prkca 4 213 0.70 85.06 129.91
6 INT6822 Gene_expression of Pdyn 1 215 0.78 35.99 125.76
7 INT7627 Negative_regulation of Positive_regulation of Ltp 2 162 0.50 41.2 106.27
8 INT4822 Localization of Ca2 1 417 0.80 99.57 96.45
9 INT3537 Positive_regulation of Car2 2 413 0.56 103.51 94.35
10 INT18755 Positive_regulation of Rvm 1 79 0.60 60 92.93
11 INT1639 Negative_regulation of OPRM1 2 107 0.59 13.86 90.37
12 INT64158 Negative_regulation of Prkca 2 121 0.59 29.8 88.66
13 INT7528 Regulation of OPRM1 2 100 0.62 20.63 80.57
14 INT13036 Positive_regulation of Positive_regulation of Ltp 2 105 0.51 23.71 77.66
15 INT9382 Regulation of TRPV1 4 149 0.62 53.99 77.46
16 INT13277 Regulation of Positive_regulation of Ltp 4 83 0.52 19.68 55.78
17 INT19488 Localization of ABAT 1 56 0.69 21.51 50.56
18 INT17561 Localization of Car2 3 303 0.79 60.95 44.52
19 INT92517 Gene_expression of Grin1 1 105 0.78 29.53 39.43
20 INT16455 Gene_expression of Drd2 4 116 0.78 22.71 38.47
21 INT43507 Gene_expression of Gabbr1 1 79 0.78 28.53 38.22
22 INT52194 Positive_regulation of Grin1 12 83 0.69 25.09 34.76
23 INT33768 Positive_regulation of Cysltr1 12 87 0.46 54.66 33.52
24 INT64918 Gene_expression of Gria2 2 108 0.74 29.95 29.67
25 INT54467 Localization of Ltp 1 41 0.58 8.86 26.88
26 INT32826 Positive_regulation of Gene_expression of Ltp 5 52 0.45 10.34 26.8
27 INT7584 Gene_expression of Crh 2 112 0.78 39.15 25.33
28 INT30276 Positive_regulation of Gene_expression of Pdyn 1 39 0.67 11.28 24.89
29 INT101225 Positive_regulation of Gria2 4 62 0.64 28.1 23.93
30 INT19580 Binding of Pag1 1 24 0.30 15.13 20.88
31 INT3060 Negative_regulation of Bche 1 94 0.59 46.75 18.51
32 INT63928 Negative_regulation of Grin1 2 51 0.56 11.81 17.57
33 INT95930 Negative_regulation of Gria2 3 63 0.56 18.37 17.04
34 INT197375 Gene_expression of Car1 4 84 0.65 16.46 16.45
35 INT92513 Regulation of Grin1 2 26 0.59 9.12 13.94
36 INT33358 Gene_expression of Cysltr1 7 46 0.62 24.18 13.36
37 INT7585 Regulation of Crh 1 24 0.58 9.88 12.97
38 INT22030 Negative_regulation of Cysltr1 1 31 0.39 21.83 12.49
39 INT25170 Positive_regulation of Localization of Car2 1 78 0.67 15.25 11.24
40 INT54466 Negative_regulation of Gene_expression of Ltp 1 19 0.38 5.44 10.91
41 INT104441 Binding of NOVA2 3 72 0.42 16.41 10.51
42 INT35284 Positive_regulation of Chrm1 17 14 0.67 5.64 10.11
43 INT36212 Positive_regulation of Csad 3 11 0.61 12.31 9.94
44 INT102865 Positive_regulation of Positive_regulation of Prkca 2 25 0.69 8.34 9.9
45 INT57039 Positive_regulation of Gene_expression of Drd2 1 16 0.50 1.98 9.48
46 INT35707 Gene_expression of Nlrp1a 1 20 0.75 9.61 9.32
47 INT21179 Negative_regulation of Crh 1 22 0.58 8.03 7.87
48 INT182750 Gene_expression of Hmgcr 3 61 0.58 17.23 7.4
49 INT75063 Regulation of Gene_expression of Drd2 1 10 0.62 2.82 7.38
50 INT110705 Positive_regulation of Positive_regulation of Grin1 6 11 0.69 4.7 7.33
51 INT187741 Gene_expression of pf 12 33 0.29 12.38 7.14
52 INT36726 Regulation of Gene_expression of Ltp 1 14 0.46 4.81 7.05
53 INT2513 Binding of Napa 4 80 0.42 4.29 6.51
54 INT5249 Gene_expression of Hrasls 1 8 0.58 10.39 6.27
55 INT83205 Negative_regulation of Negative_regulation of Prkca 1 6 0.43 1.14 4.87
56 INT146373 Negative_regulation of Positive_regulation of Cysltr1 5 11 0.05 5.39 4.44
57 INT187360 Gene_expression of Kcnn2 2 17 0.55 2.51 3.91
58 INT107415 Regulation of Kcnj9 1 6 0.62 1 3.87
59 INT81089 Positive_regulation of ASIC1 1 14 0.65 4.42 3.82
60 INT27595 Negative_regulation of EMG1 1 14 0.38 4.26 3.61
61 INT22270 Regulation of IGKV1-5 1 13 0.39 3.56 3.54
62 INT85537 Regulation of Crhr1 1 4 0.45 1.64 3.53
63 INT38190 Negative_regulation of Svs4 3 7 0.39 1.46 3.18
64 INT103739 Negative_regulation of Gene_expression of Crh 1 19 0.59 10.19 3.17
65 INT102209 Negative_regulation of Gene_expression of Drd2 1 5 0.59 0.46 3.17
66 INT91418 Transcription of Gabrg1 1 11 0.62 1.12 3.16
67 INT115301 Negative_regulation of Binding of Napa 1 16 0.33 0.6 3.11
68 INT36039 Gene_expression of Itpr3 2 19 0.72 3.75 2.93
69 INT245671 Positive_regulation of Gene_expression of Car1 1 15 0.28 4.31 2.67
70 INT123306 Negative_regulation of Positive_regulation of Chrm1 2 3 0.32 0.72 2.63
71 INT189122 Positive_regulation of Positive_regulation of Cysltr1 1 8 0.17 5.11 2.26
72 INT169318 Positive_regulation of Rxra 1 15 0.42 4.35 2.12
73 INT81500 Protein_catabolism of Snap25 1 10 0.66 1.12 2.12
74 INT33170 Binding of Chrm1 1 11 0.48 1.58 2.1
75 INT25737 Regulation of Chrm1 3 6 0.40 1.4 2
76 INT124051 Regulation of ACACA 2 4 0.60 1.1 1.98
77 INT40104 Binding of Cysltr1 1 11 0.38 4.56 1.95
78 INT115299 Regulation of Napa 1 14 0.54 0.56 1.7
79 INT181266 Gene_expression of GPSM2 13 18 0.32 0.54 1.64
80 INT148426 Gene_expression of Snap25 2 12 0.68 1.72 1.63
81 INT162547 Negative_regulation of Binding of Pag1 1 1 0.16 0.64 1.61
82 INT162546 Positive_regulation of Binding of Pag1 1 1 0.19 0.63 1.6
83 INT208718 Positive_regulation of Gene_expression of pf 2 5 0.21 2.16 1.45
84 INT169776 Gene_expression of Opn4 8 52 0.77 8.75 1.38
85 INT200459 Positive_regulation of pf 13 21 0.26 3.02 1.35
86 INT130517 Positive_regulation of AIRN 3 14 0.30 1.77 1.31
87 INT126411 Gene_expression of Csnk2a2 1 11 0.78 1.59 1.3
88 INT126408 Negative_regulation of Csnk2a2 1 3 0.38 1.75 1.3
89 INT12148 Positive_regulation of IGKV1-5 1 24 0.57 3.13 1.25
90 INT55315 Gene_expression of Tbp 1 32 0.74 14.6 1.17
91 INT12150 Negative_regulation of IGKV1-5 2 24 0.55 1.91 1.17
92 INT50146 Gene_expression of Dcn 1 18 0.51 0.9 1.17
93 INT208719 Positive_regulation of Msn 1 2 0.47 1.07 1.14
94 INT57847 Gene_expression of Chrm1 1 12 0.69 3.55 1.12
95 INT236163 Localization of Hmgcr 1 6 0.64 0.66 1.12
96 INT170511 Regulation of Localization of Car2 1 11 0.21 2.18 1.09
97 INT121792 Gene_expression of PTN 4 13 0.75 2.81 1.07
98 INT166859 Regulation of Positive_regulation of Chrm1 3 2 0.31 0.11 1.07
99 INT169319 Regulation of Gene_expression of Nlrp1a 1 2 0.60 0.31 1
100 INT273424 Positive_regulation of Gene_expression of Hrasls 1 3 0.09 0.85 0.96
101 INT234081 Gene_expression of Vamp2 1 9 0.51 0.71 0.94
102 INT52454 Localization of Tbp 1 7 0.76 2.53 0.91
103 INT208720 Regulation of pf 1 4 0.16 1.08 0.91
104 INT187739 Binding of pf 7 9 0.15 3.14 0.87
105 INT97272 Positive_regulation of Positive_regulation of Chrm1 2 2 0.34 0.3 0.85
106 INT208723 Negative_regulation of Gene_expression of pf 1 2 0.18 0.65 0.82
107 INT71876 Regulation of Tbp 1 4 0.43 1.03 0.8
108 INT350317 Positive_regulation of Gene_expression of Kcnn2 2 1 0.23 0 0.78
109 INT69771 Positive_regulation of Kcnma1 1 6 0.52 0.31 0.74
110 INT103450 Localization of Smpd2 1 3 0.09 0.98 0.73
111 INT220119 Gene_expression of Vamp1 6 2 0.07 1.14 0.71
112 INT216807 Binding of Svs4 2 3 0.25 0 0.7
113 INT62786 Negative_regulation of Chrm1 5 2 0.29 0.52 0.7
114 INT121717 Positive_regulation of Negative_regulation of Grin1 1 2 0.66 0.13 0.69
115 INT148428 Binding of Snap25 3 6 0.37 0.22 0.67
116 INT87931 Binding of IGKV1-5 1 13 0.06 2.03 0.65
117 INT174986 Gene_expression of AIRN 4 20 0.57 6.13 0.64
118 INT169778 Positive_regulation of Opn4 1 8 0.68 1.63 0.63
119 INT169316 Gene_expression of Rxrg 1 1 0.75 0.36 0.54
120 INT237791 Gene_expression of Ly6 2 4 0.11 1.04 0.53
121 INT37359 Negative_regulation of PTN 1 4 0.32 1.58 0.53
122 INT148429 Regulation of Snap25 1 2 0.27 0.15 0.53
123 INT84180 Binding of F5 1 22 0.48 18.6 0.49
124 INT81965 Gene_expression of F5 1 16 0.65 13.29 0.48
125 INT197369 Regulation of Gene_expression of Car1 1 4 0.24 0.25 0.47
126 INT224164 Binding of GPSM2 3 5 0.17 1.14 0.46
127 INT277472 Positive_regulation of PTN 2 4 0.49 1.14 0.46
128 INT50135 Positive_regulation of Dcn 1 5 0.45 0.7 0.44
129 INT169320 Regulation of Rxrg 1 1 0.23 0.32 0.44
130 INT153990 Positive_regulation of Binding of AKAP5 1 1 0.49 0.4 0.42
131 INT153991 Binding of AKAP5 1 1 0.47 0.4 0.42
132 INT92248 Negative_regulation of F5 1 7 0.43 3.28 0.4
133 INT350319 Negative_regulation of Localization of Tbp 1 1 0.20 0 0.4
134 INT73667 Positive_regulation of F5 2 6 0.60 3.38 0.39
135 INT50138 Negative_regulation of Dcn 1 3 0.42 0.45 0.39
136 INT204379 Positive_regulation of Napa 6 16 0.35 0.23 0.38
137 INT159451 Binding of Vamp1 11 2 0.05 0.5 0.37
138 INT289642 Negative_regulation of Gene_expression of GPSM2 2 1 0.13 0 0.36
139 INT273428 Positive_regulation of Vamp1 13 1 0.07 0.32 0.36
140 INT208717 Regulation of Gene_expression of pf 1 2 0.17 0.64 0.35
141 INT138335 Negative_regulation of Asah1 2 2 0.49 0.61 0.34
142 INT101539 Regulation of EMG1 3 23 0.48 0.99 0.33
143 INT232236 Negative_regulation of Gene_expression of Hmgcr 1 3 0.35 1.36 0.31
144 INT121794 Regulation of PTN 2 2 0.44 0.91 0.31
145 INT215331 Positive_regulation of Tbp 2 8 0.66 1.73 0.26
146 INT183714 Gene_expression of EMG1 1 17 0.60 1.59 0.19
147 INT237141 Regulation of Vamp1 7 2 0.05 1.03 0.19
148 INT278919 Binding of Opn1mw 1 2 0.35 0 0.18
149 INT208722 Negative_regulation of pf 1 2 0.17 0.6 0.17
150 INT121793 Localization of PTN 1 3 0.61 0.67 0.16
151 INT273438 Negative_regulation of Olfm1 1 1 0.01 0 0.16
152 INT255303 Localization of Mgst1 1 6 0.27 0.9 0.15
153 INT350321 Localization of D5Pas1 1 1 0.01 0 0.15
154 INT273425 Negative_regulation of Localization of Smpd2 1 1 0.01 0 0.14
155 INT187997 Regulation of AIRN 1 5 0.38 0.13 0.11
156 INT237797 Positive_regulation of Gene_expression of Itpr3 1 3 0.05 1.08 0.11
157 INT237792 Positive_regulation of Gene_expression of Ly6 1 2 0.07 0.71 0.11
158 INT181265 Positive_regulation of Gene_expression of GPSM2 1 2 0.24 0.19 0.11
159 INT132742 Localization of Chrm1 1 2 0.51 0.2 0.1
160 INT331160 Localization of GABBR1 1 1 0.17 0.07 0.09
161 INT249379 Positive_regulation of Vamp2 1 3 0.33 0 0.08
162 INT225369 Gene_expression of nr 1 7 0.17 1.97 0.07
163 INT273426 Positive_regulation of Positive_regulation of Vamp1 2 1 0.05 0 0.07
164 INT273433 Negative_regulation of Vamp1 2 1 0.06 0.09 0.06
165 INT273432 Positive_regulation of Gene_expression of Vamp1 1 1 0.04 0 0.06
166 INT308335 Localization of F5 1 2 0.23 1.86 0.05
167 INT308334 Localization of MIPOL1 1 1 0.01 0 0.05
168 INT207902 Binding of Mgst1 1 19 0.18 0.93 0.04
169 INT208721 Positive_regulation of Positive_regulation of pf 1 1 0.20 0 0.04
170 INT311758 Regulation of Gene_expression of Hmgcr 1 1 0.08 0 0.04
171 INT350314 Negative_regulation of Negative_regulation of Chrm1 1 1 0.29 0 0.04
172 INT308336 Transcription of PTN 1 1 0.67 0 0.03
173 INT308331 Transcription of F5 1 1 0.22 0 0.03
174 INT273429 Negative_regulation of Binding of Vamp1 1 1 0.04 0.08 0.03
175 INT350318 Negative_regulation of Localization of Chrm1 1 1 0.29 0 0.03
176 INT226094 Positive_regulation of Gene_expression of AIRN 2 3 0.12 0 0
177 INT126208 Binding of PTN 1 2 0.36 0 0
178 INT308332 Negative_regulation of Localization of PTN 1 2 0.17 0.09 0
179 INT311757 Localization of Opn4 1 1 0.64 0 0
180 INT311762 Regulation of Opn4 2 1 0.27 0.19 0
181 INT273434 Negative_regulation of Gene_expression of Vamp1 2 1 0.04 0 0
182 INT311759 Negative_regulation of Transcription of Opn4 2 1 0.37 0.15 0
183 INT308333 Negative_regulation of Gene_expression of EMG1 1 1 0.03 0.17 0
184 INT273435 Localization of Vamp1 1 1 0.08 0 0
185 INT311760 Regulation of Mrgprc1-ps 1 1 0.26 0 0
186 INT311761 Transcription of Opn4 2 1 0.59 0.16 0
187 INT273431 Regulation of Gene_expression of Vamp1 1 1 0.04 0 0
188 INT273427 Protein_catabolism of Vamp1 1 1 0.09 0 0
189 INT273437 Regulation of Binding of Vamp1 1 1 0.06 0 0
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