J:Neuropharmacology

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT157524 Binding of GRM5 and OPRM1 1 2 0.36 0 1.74
2 INT150069 Cnr1 Regulation of Cnr2 2 1 0.50 0.83 1.42
3 INT157522 GRM5 Regulation of Gene_expression of OPRM1 1 1 0.28 0 0.97
4 INT167947 Binding of STAT1 and Oprm1 1 2 0.00 0 0.86
5 INT167944 Binding of Oprm1 and Stat5a 1 2 0.00 0 0.85
6 INT159454 Binding of Inadl2 and Ppidl1 1 2 0.03 1.08 0.7
7 INT118824 OPA1 Positive_regulation of Gene_expression of Nos1 2 1 0.03 0.24 0.65
8 INT159455 Binding of Vamp1 and Ppidl1 1 2 0.00 0.84 0.57
9 INT167946 Binding of SRC and Stat5b 1 1 0.28 0 0.38
10 INT161435 OPA1 Positive_regulation of Gene_expression of Tnc 1 1 0.02 0.21 0.32
11 INT159457 Binding of Vamp1 and Inadl2 1 1 0.00 0.36 0.29
12 INT159456 Negative_regulation of Binding of Vamp1 and Ppidl1 1 1 0.00 0.42 0.28
13 INT163055 Negative_regulation of Pde10a Positive_regulation of Gene_expression of Qrfp 1 1 0.03 0 0.2

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 43 2008 0.81 518.3 1408.65
2 INT5228 Positive_regulation of Fos 14 934 0.70 209.8 503.87
3 INT11624 Gene_expression of OPRM1 3 445 0.78 72.36 294.36
4 INT9158 Gene_expression of Tnf 9 722 0.78 522.01 277.68
5 INT6852 Localization of TNF 2 883 0.81 705.95 270.84
6 INT16868 Gene_expression of Il6 7 807 0.78 499.48 256.57
7 INT1562 Localization of Crh 2 499 0.81 126.74 236.68
8 INT4759 Negative_regulation of Localization of Calca 16 294 0.59 82.62 226.45
9 INT6406 Binding of Oprm1 4 280 0.48 40.54 226.26
10 INT438 Gene_expression of Crh 1 376 0.78 159.11 169.17
11 INT4768 Positive_regulation of OPRM1 2 212 0.70 31.09 164.28
12 INT13353 Positive_regulation of Tnf 5 332 0.70 248.75 148.1
13 INT4658 Binding of OPRM1 1 188 0.48 25.96 136.24
14 INT6323 Positive_regulation of Gabrg1 8 213 0.70 45.08 124.34
15 INT65731 Gene_expression of Cnr1 2 234 0.78 63.82 109.34
16 INT4936 Localization of Tacr1 7 125 0.80 35.7 107.7
17 INT12569 Localization of Oprd1 1 94 0.81 23.81 104.56
18 INT74058 Gene_expression of Nos1 5 260 0.78 80.04 95.71
19 INT1639 Negative_regulation of OPRM1 1 107 0.59 13.86 90.37
20 INT7528 Regulation of OPRM1 2 100 0.62 20.63 80.57
21 INT8346 Gene_expression of Qrfp 1 136 0.70 19.49 70.21
22 INT2761 Regulation of Gabrg1 1 119 0.61 18.8 60.52
23 INT109431 Gene_expression of Trpa1 2 123 0.78 51.84 59.98
24 INT5016 Negative_regulation of Crh 3 129 0.59 36.74 59.28
25 INT49170 Negative_regulation of Nos1 6 116 0.59 60.66 58.87
26 INT6436 Positive_regulation of Positive_regulation of Fos 3 101 0.70 18.71 57.96
27 INT49028 Positive_regulation of Nos1 2 102 0.70 34.73 51.05
28 INT29144 Gene_expression of Rvm 1 41 0.52 29.23 47.76
29 INT62521 Phosphorylation of Oprm1 1 44 0.82 2.66 47.45
30 INT935 Localization of Gtf3a 2 124 0.70 35.72 43.3
31 INT66867 Gene_expression of Ceacam3 1 58 0.67 30.44 40.7
32 INT4449 Positive_regulation of NA 2 179 0.55 40.26 37.82
33 INT66005 Regulation of Cnr1 3 47 0.61 19.21 34.52
34 INT49431 Phosphorylation of OPRM1 1 31 0.82 2.2 29.09
35 INT5923 Negative_regulation of Rtn4 2 50 0.36 24.19 27.2
36 INT48248 Gene_expression of Scn10a 1 38 0.78 19.3 25.05
37 INT66753 Negative_regulation of Positive_regulation of Tnf 2 45 0.59 35.28 22.33
38 INT74059 Positive_regulation of Gene_expression of Nos1 4 55 0.70 11.5 21.39
39 INT5503 Negative_regulation of Gene_expression of Crh 1 38 0.59 16.82 21.34
40 INT104527 Binding of FSCN1 1 18 0.23 14.75 19.6
41 INT101578 Regulation of Cnr2 1 26 0.62 16.7 19.12
42 INT6666 Negative_regulation of PENK 1 30 0.58 9.16 17.91
43 INT4729 Positive_regulation of PPT1 1 19 0.67 7.11 17.83
44 INT12950 Gene_expression of Cat 3 85 0.75 35.94 15.76
45 INT81088 Gene_expression of ASIC1 2 26 0.77 17.8 15.07
46 INT74098 Negative_regulation of Gene_expression of Nos1 2 36 0.59 16.25 14.82
47 INT11795 Negative_regulation of Helt 1 33 0.28 6.51 14.76
48 INT51158 Positive_regulation of Tacr1 1 33 0.70 15.22 13.91
49 INT80883 Positive_regulation of Phosphorylation of OPRM1 1 13 0.69 1.03 13.65
50 INT97448 Negative_regulation of Mc1r 1 20 0.58 7.37 12.91
51 INT114578 Positive_regulation of Gene_expression of Ceacam3 1 18 0.47 14.95 12.22
52 INT32054 Gene_expression of Tnc 2 14 0.59 9.36 12.22
53 INT14034 Positive_regulation of Gene_expression of Qrfp 1 18 0.29 1.67 11.17
54 INT90114 Regulation of Gene_expression of Nos1 1 18 0.62 6.38 10.52
55 INT163054 Gene_expression of Msn 1 20 0.66 0.6 9.06
56 INT113987 Localization of IK 1 29 0.23 16.73 8.25
57 INT97623 Negative_regulation of Adc 1 17 0.56 3.81 8.14
58 INT160168 Gene_expression of Pde10a 1 10 0.74 8.66 7.94
59 INT101414 Gene_expression of Phc1 1 27 0.60 9.55 7.58
60 INT121815 Regulation of Positive_regulation of OPRM1 1 7 0.62 0.75 7.36
61 INT82610 Positive_regulation of SRC 1 53 0.67 26.89 7.27
62 INT147498 Gene_expression of GRM5 4 10 0.75 3.16 7.12
63 INT131745 Positive_regulation of Gene_expression of Trpa1 1 13 0.69 8.07 6.95
64 INT87941 Negative_regulation of DRGX 1 11 0.13 7.14 6.74
65 INT126484 Localization of Trpa1 1 15 0.80 4.08 6.64
66 INT68304 Positive_regulation of Nacc1 2 11 0.70 0.76 6.45
67 INT24536 Regulation of Localization of Tacr1 1 5 0.30 3.39 6.44
68 INT163052 Regulation of Msn 1 11 0.38 1.21 6.31
69 INT27118 Regulation of Binding of OPRM1 1 10 0.62 1.18 5.97
70 INT79491 Binding of Inadl2 4 5 0.17 1.67 5.37
71 INT139894 Negative_regulation of Msn 1 11 0.41 0.36 4.52
72 INT36309 Negative_regulation of DIO2 1 18 0.57 6.42 4.51
73 INT32053 Positive_regulation of Gene_expression of Tnc 1 5 0.45 3.4 4.13
74 INT80882 Negative_regulation of Phosphorylation of OPRM1 1 4 0.45 0.21 3.68
75 INT103351 Binding of Ppidl1 4 8 0.31 2.27 3.66
76 INT24883 Regulation of OPA1 1 14 0.45 9.73 3.44
77 INT31925 Negative_regulation of Agtr2 1 13 0.43 7.59 2.94
78 INT3605 Negative_regulation of OPA1 1 14 0.38 10.88 2.84
79 INT50335 Positive_regulation of Foxm1 1 20 0.69 5.11 2.81
80 INT7041 Negative_regulation of SP3P 1 3 0.00 1.45 2.59
81 INT140206 Binding of GRM5 1 6 0.36 1.85 2.52
82 INT81063 Regulation of Inadl2 1 4 0.18 0.74 2.37
83 INT157529 Positive_regulation of GRM5 2 3 0.48 0.59 2.07
84 INT48262 Positive_regulation of SP3P 1 3 0.00 1.55 2.06
85 INT93196 Negative_regulation of ASIC1 2 7 0.43 2.97 2
86 INT32980 Positive_regulation of Regulation of OPRM1 1 2 0.45 0 1.98
87 INT161432 Negative_regulation of Gene_expression of Tnc 1 2 0.38 1.44 1.93
88 INT78960 Binding of SOAT1 1 9 0.36 2.56 1.92
89 INT24909 Negative_regulation of Pde10a 4 4 0.43 0.87 1.87
90 INT61845 Transcription of Homer1 1 9 0.72 2.28 1.85
91 INT164010 Gene_expression of CNBP 1 7 0.53 9.13 1.71
92 INT106044 Regulation of Ppidl1 1 2 0.37 0.54 1.6
93 INT100523 Regulation of GRM5 1 2 0.26 0.49 1.51
94 INT144393 Negative_regulation of Negative_regulation of Nos1 2 2 0.32 0.96 1.15
95 INT15527 Gene_expression of FFAR1 1 19 0.61 11.15 1.08
96 INT157528 Regulation of Gene_expression of GRM5 1 1 0.43 0 0.96
97 INT157527 Negative_regulation of OR4N4 1 1 0.00 0 0.92
98 INT80385 Binding of GP9 2 4 0.35 0.26 0.89
99 INT167938 Positive_regulation of Phosphorylation of Stat5b 2 1 0.33 0 0.85
100 INT166006 Gene_expression of Scnn1a 1 2 0.46 0.32 0.83
101 INT167942 Binding of Stat5b 2 1 0.26 0 0.82
102 INT159036 Negative_regulation of Dsi1 1 1 0.11 0 0.82
103 INT16609 Localization of FFAR1 1 8 0.40 2.65 0.81
104 INT153649 Negative_regulation of Gene_expression of ASIC1 1 3 0.42 0.38 0.79
105 INT157526 Regulation of Binding of GRM5 1 1 0.43 0 0.73
106 INT159450 Localization of SP3P 2 1 0.00 0.89 0.5
107 INT166007 Negative_regulation of Gene_expression of Scnn1a 1 1 0.26 0.32 0.46
108 INT167941 Phosphorylation of Stat5b 1 1 0.58 0 0.42
109 INT159451 Binding of Vamp1 1 2 0.05 0.5 0.37
110 INT161434 Regulation of Negative_regulation of OPA1 1 1 0.03 0.2 0.32
111 INT9815 Binding of FFAR1 1 6 0.29 3.54 0.29
112 INT159453 Negative_regulation of Binding of Ppidl1 1 1 0.08 0.42 0.28
113 INT161410 Transcription of WISP3 1 1 0.67 1.17 0.28
114 INT159452 Negative_regulation of Ppidl1 1 1 0.08 0.42 0.28
115 INT159449 Negative_regulation of Positive_regulation of SP3P 1 1 0.00 0.42 0.25
116 INT167940 Regulation of Stat5b 1 1 0.43 0 0.19
117 INT163053 Regulation of Negative_regulation of Pde10a 1 1 0.45 0 0.18
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