J:Nihon Shinkei Seishin Yakurigaku Zasshi

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT112033 Gabrb3 Positive_regulation of Plcg1 1 1 0.05 0.18 1.49
2 INT112034 Gabrb3 Positive_regulation of Pik3r1 1 1 0.08 0.18 1.48
3 INT96262 Positive_regulation of Pik3cd Positive_regulation of Plcg1 1 1 0.03 0 1.39
4 INT125950 Syt17 Regulation of Trpv1 1 1 0.11 0.43 1.28
5 INT96261 Positive_regulation of Pik3cd Positive_regulation of Plcg2 1 1 0.02 0 1.21
6 INT96260 Pik3cd Regulation of Plcg2 1 1 0.02 0 0.92
7 INT112032 Positive_regulation of Oprm1 Positive_regulation of Pdia3 1 1 0.44 0.13 0.62
8 INT88080 Binding of Chrna4 and Psmb6 1 1 0.03 0.56 0.46
9 INT122271 Binding of ASIC2 and ASIC1 1 1 0.26 0.14 0.13

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5228 Positive_regulation of Fos 1 934 0.70 209.8 503.87
2 INT50058 Negative_regulation of Cpox 1 907 0.58 426.28 428.29
3 INT5895 Gene_expression of Oprm1 4 525 0.78 120.67 407.29
4 INT76660 Gene_expression of Trpv1 2 691 0.78 329.46 386.42
5 INT16260 Gene_expression of Bdnf 2 671 0.78 283.44 339.1
6 INT5540 Positive_regulation of Oprm1 6 344 0.70 76.77 319.71
7 INT4941 Positive_regulation of Oprd1 1 345 0.70 74.26 304.41
8 INT63932 Positive_regulation of Ephb1 1 537 0.70 259.67 296.14
9 INT87687 Positive_regulation of Trpv1 3 409 0.70 210.24 257.59
10 INT5501 Regulation of Oprd1 2 283 0.62 55.1 249.9
11 INT2391 Negative_regulation of PTGS1 1 501 0.59 207.62 205.6
12 INT63934 Phosphorylation of Ephb1 1 377 0.82 150.52 188.66
13 INT12602 Negative_regulation of Oprm1 2 190 0.59 36.11 177.85
14 INT26472 Regulation of Oprm1 1 191 0.62 35.84 173.1
15 INT51921 Gene_expression of Cpox 1 501 0.73 229.81 157.81
16 INT64161 Positive_regulation of Prkca 1 213 0.70 85.06 129.91
17 INT1438 Localization of Pomc 3 360 0.81 101.26 116.47
18 INT16253 Positive_regulation of Gene_expression of Bdnf 2 196 0.70 92.67 113.01
19 INT203 Positive_regulation of Pomc 1 257 0.70 90.56 92.84
20 INT18032 Positive_regulation of Oprk1 1 108 0.70 30.78 89.7
21 INT67682 Localization of Bdnf 1 204 0.81 72.36 88.92
22 INT64158 Negative_regulation of Prkca 1 121 0.59 29.8 88.66
23 INT12476 Negative_regulation of TRPV1 1 124 0.59 47.95 77.98
24 INT1080 Negative_regulation of Ache 1 343 0.59 108.51 72.4
25 INT8962 Gene_expression of Cpe 1 110 0.71 39.67 71.67
26 INT87686 Positive_regulation of Gene_expression of Trpv1 1 101 0.70 72.41 69.15
27 INT7872 Positive_regulation of P9Ehs1 3 74 0.50 18.54 66.16
28 INT66531 Gene_expression of Pnoc 1 88 0.78 22.9 65.11
29 INT24989 Positive_regulation of Cfp 3 125 0.61 29.55 64.9
30 INT8733 Localization of Oprm1 2 61 0.75 7.55 64.61
31 INT1169 Negative_regulation of Bche 1 322 0.59 149.22 61.27
32 INT9196 Gene_expression of PTGS1 1 215 0.77 96.99 60.5
33 INT929 Positive_regulation of Oprl1 1 64 0.70 14.67 52.84
34 INT29105 Positive_regulation of OPRK1 2 68 0.70 7.06 44.69
35 INT1319 Gene_expression of Oprl1 1 65 0.78 9.34 42.41
36 INT1596 Negative_regulation of Oprl1 2 61 0.57 13.5 38.41
37 INT88081 Negative_regulation of Gene_expression of Oprm1 1 45 0.59 16.56 37.5
38 INT17736 Gene_expression of Cfp 3 111 0.65 40.68 36.61
39 INT11087 Positive_regulation of Drd2 1 54 0.69 12.4 31.43
40 INT7845 Regulation of OPRK1 1 44 0.62 4.54 30.49
41 INT69483 Transcription of OPRM1 1 45 0.72 7.31 30.22
42 INT6660 Positive_regulation of Jun 2 148 0.69 67.58 29.73
43 INT276 Regulation of Ache 1 83 0.62 16.75 25.99
44 INT112036 Phosphorylation of Trpv1 1 51 0.82 18.59 25.6
45 INT122570 Negative_regulation of Akt1 1 173 0.59 91.44 25.53
46 INT13838 Positive_regulation of Drd1a 2 48 0.70 9.83 23.42
47 INT50970 Positive_regulation of Ntrk1 1 51 0.57 29.38 22.83
48 INT6868 Gene_expression of GFAP 1 136 0.78 84.65 22.7
49 INT112029 Positive_regulation of Pik3r1 1 90 0.67 38.76 20.95
50 INT13108 Binding of MTG1 2 35 0.47 6.36 20.5
51 INT6807 Regulation of Gabrd 1 39 0.62 9.22 18.74
52 INT112338 Localization of Rvm 1 11 0.31 9.51 17.61
53 INT125947 Gene_expression of Adora2b 1 57 0.75 23.69 17
54 INT33915 Regulation of Positive_regulation of Oprm1 1 22 0.60 2.44 16.43
55 INT112027 Gene_expression of Pik3r1 1 58 0.75 30.9 15.95
56 INT124371 Negative_regulation of Gsk3b 1 170 0.55 87.92 15.51
57 INT12837 Binding of SIGMAR1 1 57 0.48 5.31 15.49
58 INT26729 Negative_regulation of Drd2 1 28 0.55 9.32 15.17
59 INT81088 Gene_expression of ASIC1 1 26 0.77 17.8 15.07
60 INT82929 Gene_expression of Plat 1 58 0.78 26.96 13.85
61 INT85510 Positive_regulation of Bdkrb2 1 23 0.70 12.08 12.68
62 INT146197 Positive_regulation of Rhoa 1 60 0.68 34.12 12.02
63 INT96259 Positive_regulation of Plcg1 5 11 0.49 3.01 11.15
64 INT112037 Negative_regulation of Positive_regulation of Trpv1 1 19 0.59 8.9 10.55
65 INT75955 Gene_expression of Drd3 1 19 0.77 4.39 10.07
66 INT6867 Positive_regulation of Gene_expression of GFAP 1 22 0.67 13.46 9.75
67 INT21952 Gene_expression of GDNF 1 42 0.78 20.32 9.62
68 INT117497 Positive_regulation of F2r 1 18 0.57 14.45 8.13
69 INT110004 Gene_expression of Plcg1 3 7 0.41 2.61 7.87
70 INT62372 Positive_regulation of Localization of Oprm1 1 8 0.50 0.46 7.71
71 INT22834 Negative_regulation of CYP21A2 1 28 0.58 23.07 7.13
72 INT64370 Gene_expression of Neurod1 1 22 0.75 5.19 7.1
73 INT88079 Gene_expression of Chrna4 1 20 0.76 8.52 6.98
74 INT53311 Positive_regulation of Gene_expression of Cfp 3 20 0.42 4.39 6.62
75 INT124488 Positive_regulation of Gene_expression of Plat 1 14 0.70 5.46 6.52
76 INT97600 Regulation of Transcription of OPRM1 1 8 0.52 1.14 6.21
77 INT124825 Transcription of Plat 2 8 0.70 3.15 5.68
78 INT123726 Positive_regulation of Notch1 1 23 0.70 7.2 5.65
79 INT101497 Phosphorylation of Prkce 1 9 0.81 2.55 5.59
80 INT96258 Positive_regulation of Pik3cd 2 14 0.43 8.74 5.16
81 INT16051 Regulation of Tspo 1 6 0.45 2.81 4.95
82 INT98453 Positive_regulation of Src 2 19 0.47 7.84 4.62
83 INT69217 Gene_expression of Notch1 1 20 0.78 7.8 4.41
84 INT112038 Positive_regulation of P2ry2 1 8 0.45 2.41 4.4
85 INT81750 Regulation of Ntrk1 1 13 0.52 6.03 4.37
86 INT15450 Positive_regulation of Gene_expression of Cpe 1 11 0.34 4.53 4.34
87 INT11946 Transcription of Ache 1 18 0.69 2.62 4.13
88 INT93200 Gene_expression of ASIC2 1 6 0.60 3.27 3.7
89 INT88008 Positive_regulation of Gene_expression of GDNF 1 14 0.70 8.9 3.61
90 INT137350 Phosphorylation of Src 1 13 0.45 4.14 3.32
91 INT52166 Positive_regulation of Positive_regulation of OPRK1 1 2 0.57 0.48 2.74
92 INT85938 Localization of GRIK1 1 2 0.58 1.19 2.68
93 INT120551 Negative_regulation of Rock2 1 8 0.52 2.73 2.53
94 INT124826 Positive_regulation of Transcription of Plat 1 3 0.68 0.33 2.38
95 INT112026 Gene_expression of Pik3cd 1 6 0.72 4.89 2.34
96 INT85630 Positive_regulation of Tyr 1 11 0.56 3.07 2.31
97 INT74361 Negative_regulation of Gabrb3 1 4 0.58 0.73 2.28
98 INT140036 Positive_regulation of Gene_expression of Notch1 1 6 0.61 2 1.86
99 INT16070 Gene_expression of MTG1 1 6 0.75 5.42 1.65
100 INT52876 Gene_expression of H3 1 16 0.77 6.87 1.36
101 INT48192 Gene_expression of Setd1a 1 8 0.42 4.41 1.26
102 INT112028 Regulation of Pik3cd 1 2 0.19 0.22 1.25
103 INT31381 Positive_regulation of Gbp1 1 5 0.45 1.82 1.22
104 INT135218 Positive_regulation of Gene_expression of Serpini1 3 1 0.67 1.02 1.21
105 INT81768 Negative_regulation of Chrna4 2 5 0.42 1.97 1.2
106 INT135217 Gene_expression of Serpini1 3 1 0.75 1.02 1.2
107 INT112031 Positive_regulation of Ppargc1b 1 1 0.06 0.06 1.19
108 INT125948 Positive_regulation of pk 1 2 0.67 0.54 1.13
109 INT146553 Positive_regulation of Rock2 1 4 0.44 2.56 1.09
110 INT88083 Negative_regulation of Drd3 2 3 0.58 0.88 1.01
111 INT104351 Positive_regulation of Etohcta1 1 2 0.01 1.14 0.99
112 INT151362 Positive_regulation of Pas5a 1 1 0.53 0 0.96
113 INT131719 Negative_regulation of Serpini1 1 2 0.42 0.63 0.89
114 INT31014 Negative_regulation of Setd1a 1 4 0.27 1.11 0.88
115 INT156945 Positive_regulation of Negative_regulation of Gsk3b 1 6 0.38 4.58 0.82
116 INT88078 Negative_regulation of Chrm4 2 3 0.25 2.74 0.61
117 INT79156 Regulation of Gene_expression of MTG1 1 2 0.44 0.48 0.59
118 INT156944 Positive_regulation of Setd1a 1 2 0.30 1.31 0.41
119 INT88082 Negative_regulation of Drd4 1 1 0.18 0.65 0.35
120 INT156943 Negative_regulation of Negative_regulation of Setd1a 1 1 0.18 0.71 0.32
121 INT128973 Binding of Cyp4a10 2 3 0.38 2.14 0.28
122 INT156942 Positive_regulation of Gene_expression of Setd1a 1 1 0.21 0.58 0.28
123 INT128974 Binding of Nit2 1 1 0.02 0.17 0.1
124 INT66203 Regulation of Binding of SIGMAR1 1 1 0.44 0.19 0.09
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