J:Obstetrics and Gynecology International

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 2 0.06 1.61 0.69
2 INT324897 Binding of Ptbp1 and Il1 1 1 0.01 0.62 0.3
3 INT239226 Binding of Edn1 and Ednra 2 3 0.06 1.59 0.26
4 INT324899 Edn1 Positive_regulation of Positive_regulation of Mmp9 1 1 0.10 0.66 0.16
5 INT324894 Edn1 Positive_regulation of Gene_expression of Mmp3 1 1 0.07 0.66 0.16
6 INT324898 Ece1 Regulation of Gene_expression of Edn1 1 2 0.17 0.8 0.14
7 INT324702 PLOD1 Positive_regulation of CGA 1 2 0.03 1.1 0.1
8 INT324731 Binding of Prkaca and HR 1 1 0.00 1.11 0.08
9 INT324732 Positive_regulation of Binding of Prkaca and HR 1 1 0.00 1.12 0.08
10 INT324896 Ece1 Positive_regulation of Negative_regulation of Edn1 1 1 0.19 0.42 0.07
11 INT319171 Binding of Cgn and Hdac1 1 1 0.00 0 0
12 INT304029 Binding of PTEN and TP53 1 1 0.35 0.62 0
13 INT304020 AR Regulation of TP53 1 1 0.24 1.11 0
14 INT304022 Binding of PIK3CG and TP53 1 1 0.10 0.72 0
15 INT324705 CGA Positive_regulation of PLOD1 1 1 0.04 0 0
16 INT304028 MDM2 Regulation of TP53 1 1 0.19 1.11 0
17 INT304014 Binding of MSI1 and SGCG 1 1 0.00 1.92 0
18 INT304012 Binding of AKT1 and PIK3CA 1 2 0.28 1.14 0
19 INT304018 Regulation of Binding of PIK3CG and TP53 1 1 0.12 0.73 0
20 INT304025 Binding of PIK3CA and TP53 1 1 0.30 0.67 0
21 INT304015 Binding of PIK3CA and PIK3CG 1 1 0.09 0.67 0
22 INT324704 PLOD1 Positive_regulation of HRASLS 1 1 0.05 0 0
23 INT304019 Binding of AKT1 and TP53 1 1 0.27 0.72 0
24 INT304026 Binding of PIK3CG and PTEN 1 1 0.11 0.62 0
25 INT324706 CGA Positive_regulation of HRASLS 1 1 0.01 0 0
26 INT305350 Pten Regulation of Phosphorylation of Akt1 1 1 0.05 0.95 0
27 INT319170 Casp3 Regulation of Hdac1 1 1 0.01 0.27 0
28 INT305336 TP53 Negative_regulation of Phosphorylation of RB1 1 1 0.29 0.96 0
29 INT304027 Negative_regulation of PTEN Positive_regulation of Positive_regulation of AKT1 1 1 0.32 1.86 0
30 INT304017 Regulation of Binding of AKT1 and TP53 1 1 0.32 0.73 0
31 INT304023 SFRP1 Regulation of Binding of MSI1 1 1 0.04 1.78 0
32 INT304016 SFRP4 Regulation of Binding of MSI1 1 1 0.04 1.78 0
33 INT304013 Binding of SUZ12 and JAZF1 1 2 0.30 1.89 0
34 INT304024 Binding of AKT1 and PTEN 1 2 0.33 1.08 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 1 3152 0.78 2515.62 929.82
2 INT5059 Positive_regulation of TNF 1 1050 0.70 896.51 322.81
3 INT68684 Gene_expression of VEGFA 1 2371 0.78 1742.52 259.2
4 INT6482 Positive_regulation of Gene_expression of TNF 1 659 0.70 569.88 210
5 INT7533 Gene_expression of Tlr4 1 720 0.78 343.22 121.57
6 INT8243 Positive_regulation of Il6 2 451 0.70 358.24 119.28
7 INT1793 Localization of CGA 2 379 0.81 67.38 114.69
8 INT1760 Gene_expression of PTGER2 1 524 0.57 226.94 96.4
9 INT2893 Localization of Oxt 1 219 0.80 28.96 79.43
10 INT920 Localization of PLOD1 2 223 0.81 42.25 78.7
11 INT1599 Positive_regulation of ADCY1 1 146 0.67 30.05 64.9
12 INT11937 Localization of Il6 1 228 0.81 139.83 64.39
13 INT17401 Gene_expression of IGF1 1 475 0.78 232.18 62.07
14 INT9196 Gene_expression of PTGS1 1 215 0.77 96.99 60.5
15 INT546 Binding of ALB 1 311 0.48 85.98 60.14
16 INT31116 Gene_expression of Casp3 6 192 0.78 78.21 57.43
17 INT96937 Gene_expression of Mmp9 4 191 0.75 150.3 56.01
18 INT937 Positive_regulation of Oxt 2 195 0.70 37.82 49.3
19 INT106525 Phosphorylation of Akt1 1 436 0.82 183.81 47.82
20 INT115384 Positive_regulation of Mmp9 3 121 0.68 94.74 43.02
21 INT3933 Positive_regulation of PLOD1 1 128 0.70 30.76 42.03
22 INT3758 Gene_expression of ALB 5 326 0.78 184.65 38.75
23 INT927 Gene_expression of Oxt 4 184 0.78 44.71 35.79
24 INT10248 Gene_expression of KRT20 2 436 0.78 231.96 32.88
25 INT3117 Regulation of Oxt 1 103 0.61 17.93 32.28
26 INT48693 Regulation of VEGFA 1 268 0.62 191.88 31.52
27 INT56809 Binding of Tlr4 3 184 0.48 106.02 31.18
28 INT7975 Regulation of PLOD1 1 97 0.62 20.9 30.51
29 INT28361 Gene_expression of TP53 12 443 0.78 384.86 28.8
30 INT7035 Regulation of CGA 1 87 0.45 29.04 28.45
31 INT6364 Gene_expression of Edn1 9 123 0.78 73.76 28.43
32 INT5206 Gene_expression of AR 3 316 0.78 113.83 27.29
33 INT1765 Positive_regulation of Gene_expression of PTGER2 1 140 0.51 68.68 27
34 INT3760 Positive_regulation of ALB 1 142 0.70 87.46 26.7
35 INT1638 Negative_regulation of PLOD1 3 92 0.59 21.69 26.61
36 INT9682 Positive_regulation of IGF1 1 238 0.70 120.03 26.36
37 INT11159 Gene_expression of EGFR 6 698 0.78 548.93 25.69
38 INT140193 Gene_expression of Mmp3 1 58 0.71 49.65 25.4
39 INT2614 Gene_expression of CGA 17 187 0.78 105.89 24.77
40 INT86295 Gene_expression of Mmp2 1 114 0.76 73.68 24.25
41 INT72370 Gene_expression of Timp1 1 82 0.65 57.52 24.16
42 INT17275 Gene_expression of HIVEP1 8 267 0.75 232.07 24.06
43 INT15390 Positive_regulation of Edn1 1 64 0.70 47.36 23.8
44 INT34487 Localization of MMP2 1 56 0.81 31.41 23.61
45 INT9292 Positive_regulation of SGCG 1 93 0.67 35.13 23.48
46 INT7383 Localization of VIP 1 53 0.81 17.7 22.65
47 INT2386 Gene_expression of Pgr 2 112 0.78 45.46 22.19
48 INT170313 Gene_expression of Mmp1a 4 50 0.65 38.53 21.36
49 INT11157 Binding of EGF 1 88 0.48 53.73 21.25
50 INT73593 Gene_expression of BAX 1 173 0.76 147.81 20.94
51 INT1792 Positive_regulation of CGA 1 123 0.70 64.73 20.79
52 INT50814 Positive_regulation of Mmp2 3 72 0.68 51.37 20.42
53 INT116282 Gene_expression of Mmp13 1 83 0.75 45.4 20.18
54 INT89396 Phosphorylation of AKT1 1 225 0.82 111.66 19.61
55 INT86187 Positive_regulation of AKT1 5 199 0.69 122.13 19.44
56 INT11938 Positive_regulation of Localization of Il6 1 61 0.70 35.72 18.25
57 INT13510 Gene_expression of ERBB2 10 530 0.78 405.68 16.79
58 INT65856 Positive_regulation of TP53 4 138 0.67 112.65 16.71
59 INT28950 Positive_regulation of Gene_expression of IGF1 1 99 0.69 46.9 16.47
60 INT10214 Gene_expression of VIM 1 153 0.78 115.88 16.29
61 INT97245 Gene_expression of AKT1 1 217 0.77 119.63 15.59
62 INT7970 Gene_expression of PLOD1 20 120 0.71 44.42 15.54
63 INT113606 Positive_regulation of Gene_expression of Mmp9 2 46 0.64 44 15.07
64 INT20420 Gene_expression of MYC 1 99 0.75 49.32 14.36
65 INT94774 Regulation of CDKN2A 2 43 0.60 44.41 13.99
66 INT78472 Gene_expression of CDKN2A 1 223 0.78 173.76 13.61
67 INT86383 Negative_regulation of EGFR 1 258 0.59 173.94 13.32
68 INT27242 Gene_expression of PGR 1 153 0.75 98.77 12.79
69 INT102731 Regulation of ABCB1 2 29 0.62 5.36 11.67
70 INT25963 Gene_expression of DES 1 122 0.75 98.81 11.25
71 INT151168 Gene_expression of Pten 1 60 0.78 35.63 10.54
72 INT140191 Positive_regulation of Gene_expression of Mmp13 1 25 0.67 13.47 9.71
73 INT75137 Regulation of Akt1 1 74 0.48 37.89 9.7
74 INT69264 Gene_expression of KIT 2 207 0.78 179.41 8.95
75 INT12095 Negative_regulation of Edn1 1 26 0.59 12.01 8.79
76 INT119831 Gene_expression of PTEN 8 55 0.75 40.37 8.57
77 INT108202 Positive_regulation of PIK3CG 1 47 0.67 25.83 8.25
78 INT96068 Positive_regulation of Timp1 1 30 0.58 23.94 8.17
79 INT53487 Gene_expression of TSC1 1 81 0.58 77.71 7.94
80 INT111607 Gene_expression of CDH1 4 103 0.75 90.45 7.77
81 INT57748 Positive_regulation of Gene_expression of TP53 5 85 0.69 79.55 7.49
82 INT92138 Binding of CDKN2A 1 28 0.37 25.64 7.47
83 INT168381 Positive_regulation of Mmp3 2 24 0.58 19.12 7.03
84 INT53704 Negative_regulation of Col7a1 1 42 0.35 22.4 6.88
85 INT167049 Binding of Ednra 1 3 0.07 3.47 6.84
86 INT67568 Positive_regulation of Localization of MMP2 1 14 0.31 8.58 6.79
87 INT155780 Gene_expression of Mmp8 1 19 0.77 15.85 6.33
88 INT123551 Regulation of Mmp2 2 17 0.57 11.6 6
89 INT38671 Positive_regulation of KRT20 3 62 0.53 40.17 5.6
90 INT157802 Negative_regulation of Timp2 2 7 0.54 5.75 5.51
91 INT77281 Negative_regulation of HIVEP1 1 132 0.49 102.78 5.36
92 INT174688 Binding of Tlr2 2 45 0.42 36.65 5.25
93 INT15376 Positive_regulation of Gene_expression of ERBB2 8 215 0.70 168.54 5.23
94 INT60585 Regulation of TP53 1 59 0.59 54.55 5.21
95 INT60252 Binding of HIVEP1 1 59 0.32 65.12 5.06
96 INT30738 Negative_regulation of Gene_expression of ALB 1 32 0.59 19.01 5.04
97 INT11158 Positive_regulation of Gene_expression of EGFR 2 165 0.70 131.26 4.93
98 INT105336 Regulation of AKT1 2 52 0.56 32.53 4.89
99 INT10115 Gene_expression of INSR 1 31 0.75 11.98 4.86
100 INT62684 Negative_regulation of TP53 2 66 0.58 66.09 4.62
101 INT220861 Positive_regulation of Mmp8 2 14 0.50 12.21 4.6
102 INT57749 Negative_regulation of Gene_expression of TP53 1 39 0.56 36.79 4.45
103 INT109450 Positive_regulation of Phosphorylation of AKT1 1 62 0.64 25.18 4.21
104 INT86919 Negative_regulation of PIK3CG 1 40 0.57 21.16 3.97
105 INT142754 Binding of Myd88 1 20 0.36 9.61 3.8
106 INT86293 Positive_regulation of Gene_expression of Mmp2 1 21 0.64 11.69 3.79
107 INT151171 Positive_regulation of Pten 3 20 0.55 13.3 3.54
108 INT228465 Positive_regulation of Timp2 1 4 0.64 6.29 3.54
109 INT116281 Negative_regulation of Gene_expression of Mmp13 1 15 0.41 9.96 3.41
110 INT64766 Gene_expression of TWIST1 1 41 0.76 37.89 3.4
111 INT51607 Positive_regulation of DES 1 33 0.67 32.24 3.29
112 INT94164 Phosphorylation of RB1 2 83 0.80 48.84 3.21
113 INT15837 Binding of CGA 1 31 0.41 12.06 3.17
114 INT179338 Gene_expression of Timp2 1 7 0.55 5.75 3.13
115 INT192676 Binding of PTEN 2 14 0.46 10.58 3.06
116 INT89392 Negative_regulation of Positive_regulation of AKT1 1 23 0.50 15.69 3.02
117 INT200670 Gene_expression of AKT2 3 25 0.75 16.25 3
118 INT53374 Binding of Edn1 1 17 0.43 11.66 2.98
119 INT8103 Binding of TP53 1 46 0.44 40.2 2.96
120 INT170324 Negative_regulation of Gene_expression of Mmp1a 3 8 0.13 6.28 2.94
121 INT25031 Negative_regulation of Gene_expression of PLOD1 2 14 0.54 3.86 2.89
122 INT104182 Gene_expression of ABCC2 1 19 0.76 5.92 2.88
123 INT37734 Positive_regulation of Ang 1 18 0.46 9.17 2.87
124 INT132760 Gene_expression of Pgr 1 47 0.66 28.17 2.85
125 INT184477 Negative_regulation of Pten 2 27 0.59 15.61 2.8
126 INT89397 Positive_regulation of PIK3CA 3 33 0.67 16.98 2.78
127 INT220858 Positive_regulation of Mmp1a 10 15 0.38 9.11 2.77
128 INT172797 Negative_regulation of Mmp1a 1 8 0.24 6.47 2.74
129 INT184257 Positive_regulation of Gene_expression of Mmp8 1 7 0.49 6.32 2.74
130 INT74293 Positive_regulation of BAK1 1 13 0.60 14.13 2.73
131 INT17276 Negative_regulation of Gene_expression of HIVEP1 2 27 0.42 26.85 2.61
132 INT22161 Regulation of Gene_expression of Oxt 1 10 0.52 3.96 2.59
133 INT243033 Localization of Mmp8 2 8 0.65 5.59 2.52
134 INT119838 Positive_regulation of PTEN 3 25 0.67 21.71 2.5
135 INT92141 Negative_regulation of CDKN2A 2 53 0.57 44.23 2.48
136 INT25208 Gene_expression of IGF2 1 43 0.74 30.64 2.31
137 INT31118 Localization of Casp3 1 17 0.73 11.55 2.3
138 INT12033 Binding of PLOD1 1 15 0.48 8.04 2.3
139 INT179885 Regulation of PTEN 4 8 0.26 11.88 2.18
140 INT38674 Regulation of KRT20 1 32 0.44 19 2.15
141 INT68496 Binding of PGR 1 26 0.48 16.36 2.09
142 INT36616 Positive_regulation of Binding of ALB 1 8 0.67 3 2.07
143 INT172554 Positive_regulation of Gene_expression of Mmp1a 1 7 0.16 4.48 2.05
144 INT107987 Gene_expression of MRC1 1 27 0.75 36.94 1.99
145 INT2982 Positive_regulation of Gene_expression of CGA 2 17 0.59 9.08 1.99
146 INT125080 Positive_regulation of Positive_regulation of TP53 3 21 0.58 16.16 1.98
147 INT81641 Gene_expression of Ctnnb1 1 23 0.72 14.93 1.97
148 INT7972 Positive_regulation of Gene_expression of PLOD1 2 15 0.42 5.73 1.96
149 INT115665 Transcription of ABCB1 1 9 0.71 3.69 1.91
150 INT20421 Positive_regulation of MYC 1 19 0.67 10.43 1.9
151 INT56925 Negative_regulation of TSC1 2 54 0.52 63.39 1.87
152 INT48792 Regulation of ERBB2 2 48 0.57 36.56 1.8
153 INT86909 Negative_regulation of MSH2 2 9 0.41 12.65 1.7
154 INT109975 Positive_regulation of Kras 2 14 0.45 12.72 1.68
155 INT107992 Gene_expression of MSH2 1 39 0.78 37.09 1.6
156 INT94169 Negative_regulation of Phosphorylation of RB1 1 16 0.41 8.87 1.57
157 INT65684 Gene_expression of MDM2 1 30 0.62 24.94 1.55
158 INT52962 Binding of ERBB2 1 77 0.47 50.03 1.49
159 INT243876 Gene_expression of GPHN 2 8 0.75 2.63 1.49
160 INT107985 Gene_expression of MLH1 3 29 0.67 31.31 1.46
161 INT39050 Positive_regulation of PGF 1 14 0.49 8.05 1.43
162 INT162462 Protein_catabolism of TP53 1 8 0.86 7.89 1.41
163 INT304045 Transcription of PTEN 1 2 0.51 4.12 1.4
164 INT92383 Gene_expression of KRAS 2 38 0.65 32.94 1.32
165 INT137382 Negative_regulation of Gene_expression of KRT20 1 22 0.58 12.29 1.29
166 INT139237 Negative_regulation of Gene_expression of CDH1 3 23 0.57 24.31 1.28
167 INT210399 Gene_expression of IGF2R 2 22 0.65 17.1 1.23
168 INT10117 Positive_regulation of INSR 1 10 0.43 4.71 1.22
169 INT190014 Regulation of Pten 1 8 0.62 6.03 1.2
170 INT119832 Positive_regulation of Gene_expression of PTEN 1 12 0.49 7.12 1.19
171 INT135556 Localization of AKT1 1 38 0.69 12.78 1.17
172 INT220206 Gene_expression of CCNB2 1 4 0.67 3.75 1.16
173 INT157765 Negative_regulation of CDH1 1 32 0.53 35.72 1.15
174 INT146546 Gene_expression of MSI1 7 22 0.48 22.91 1.15
175 INT111605 Positive_regulation of CDH1 2 12 0.50 7.95 1.15
176 INT86908 Negative_regulation of MLH1 1 7 0.43 6.98 1.12
177 INT170319 Regulation of Gene_expression of Mmp1a 1 5 0.11 2.72 1.11
178 INT118952 Gene_expression of Hist1h3f 1 13 0.21 3.58 1.05
179 INT87637 Localization of Ang 1 11 0.63 4.42 1.03
180 INT92139 Binding of MLH1 1 12 0.42 15.62 1
181 INT163280 Negative_regulation of Phosphorylation of CCND1 1 6 0.19 3.92 0.87
182 INT297531 Negative_regulation of Ece1 3 5 0.32 5.49 0.87
183 INT163289 Phosphorylation of CCND1 2 7 0.36 4.81 0.81
184 INT275575 Gene_expression of FOLR1 1 12 0.66 2.81 0.8
185 INT102813 Regulation of Gene_expression of TP53 1 25 0.59 25.95 0.75
186 INT108204 Regulation of PIK3CG 2 9 0.12 4.16 0.75
187 INT92142 Binding of MSH2 1 5 0.46 5.64 0.75
188 INT251303 Binding of HR 1 14 0.47 3.87 0.7
189 INT86370 Regulation of CDH1 1 10 0.54 13.89 0.7
190 INT37490 Negative_regulation of Cyp1b1 1 3 0.30 1.57 0.68
191 INT324890 Negative_regulation of Negative_regulation of Timp2 1 2 0.40 1.09 0.68
192 INT181282 Transcription of INCENP 1 10 0.11 1.21 0.66
193 INT206139 Phosphorylation of KRT20 1 8 0.48 9.1 0.66
194 INT324883 Positive_regulation of Ptbp1 3 1 0.17 2.66 0.66
195 INT44478 Negative_regulation of PTEN 8 32 0.57 27.45 0.63
196 INT47038 Gene_expression of SFRP1 1 14 0.67 9.6 0.63
197 INT304060 Positive_regulation of AGR2 1 2 0.70 13 0.63
198 INT161322 Localization of PTEN 1 9 0.73 5.65 0.57
199 INT170986 Positive_regulation of BCO2 1 2 0.04 1.06 0.55
200 INT201846 Positive_regulation of SFRP4 1 4 0.37 2.74 0.54
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