J:PLoS Biology

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT211710 Binding of Mc1r and a 7 4 0.44 0.37 4.78
2 INT249013 Gabrg1 Negative_regulation of Per2 1 4 0.34 0.07 2.31
3 INT305741 Binding of Kcnk2 and Sort1 1 5 0.54 1.01 1.8
4 INT249005 Gabrg1 Positive_regulation of Per2 1 3 0.39 0 1.7
5 INT101926 Binding of Dio1 and Drd2 4 1 0.28 0.39 1.66
6 INT214372 Ptprq Positive_regulation of Akt1 1 2 0.04 0.88 1.43
7 INT214369 Pik3cb Positive_regulation of Akt1 1 2 0.56 0.87 1.41
8 INT251142 Binding of Dlg4 and Grin2a 3 1 0.30 0.5 1.24
9 INT249014 Gabrg1 Regulation of Per2 1 2 0.31 0 1.24
10 INT184919 Binding of da and Slc6a3 1 2 0.12 0.33 1.23
11 INT249002 Gabrg1 Positive_regulation of Protein_catabolism of Per1 1 2 0.35 0.09 1.15
12 INT305734 Binding of Sort1 and Trpv1 1 2 0.01 0.5 1.08
13 INT249012 Binding of Akt1 and Gabrg1 1 2 0.01 0 0.9
14 INT305742 Binding of Sort1 and Gtf3a 1 2 0.01 0.64 0.88
15 INT184916 Binding of da and Th 1 2 0.09 1.22 0.87
16 INT214370 Slc6a3 Regulation of Amph 1 2 0.14 0.44 0.82
17 INT184918 da Positive_regulation of Negative_regulation of Th 1 1 0.14 0.14 0.77
18 INT353630 Binding of Psmd1 and Shbdp1 1 2 0.02 0 0.76
19 INT249023 Gabrg1 Positive_regulation of Csn2 1 2 0.02 0 0.74
20 INT248998 Gabrg1 Regulation of Luc7l3 1 1 0.05 0 0.69
21 INT249018 Gabrg1 Regulation of Localization of Per2 1 1 0.35 0 0.69
22 INT214368 Pik3cb Regulation of Ubqln1 1 1 0.01 0.36 0.68
23 INT249010 Gabrg1 Regulation of Positive_regulation of Per1 1 1 0.33 0 0.67
24 INT249008 Gabrg1 Regulation of Per1 1 1 0.33 0 0.67
25 INT213895 Mastl Regulation of Gene_expression of Cnr1 1 2 0.17 0.26 0.66
26 INT200808 Binding of Akt1 and Insrr 2 1 0.00 0.98 0.61
27 INT249027 Gabrg1 Negative_regulation of Luc7l3 1 1 0.05 0.07 0.59
28 INT249029 Binding of Csn2 and Insrr 1 1 0.00 0 0.59
29 INT248993 Binding of Csn2 and Ptar1 1 1 0.00 0 0.59
30 INT248994 Binding of Akt1 and Ptar1 1 1 0.00 0 0.58
31 INT305744 Fst Positive_regulation of Creb1 1 1 0.12 0.33 0.57
32 INT305732 Tst Positive_regulation of Creb1 1 1 0.12 0.33 0.57
33 INT249009 Gabrg1 Regulation of Gene_expression of Per2 1 1 0.40 0 0.56
34 INT249022 Gabrg1 Regulation of Gene_expression of Luc7l3 1 1 0.07 0 0.56
35 INT249001 Gabrg1 Positive_regulation of Arntl 1 1 0.29 0 0.55
36 INT249006 Gabrg1 Positive_regulation of Transcription of Arntl 1 1 0.31 0 0.55
37 INT249024 Gabrg1 Positive_regulation of Transcription of Per1 1 1 0.59 0 0.55
38 INT249020 Gabrg1 Positive_regulation of Per1 1 1 0.40 0 0.55
39 INT263776 Grin1 Positive_regulation of Ltp 2 1 0.17 0.17 0.54
40 INT263756 Binding of Bmp1 and Neto1 1 2 0.30 0.11 0.54
41 INT248997 Gabrg1 Positive_regulation of Clock 1 1 0.37 0 0.54
42 INT248995 Gabrg1 Regulation of Transcription of Clock 1 1 0.36 0 0.54
43 INT249007 Gabrg1 Regulation of Transcription of Per2 1 1 0.35 0 0.54
44 INT204494 Binding of App and Fmr1 1 14 0.54 4.39 0.54
45 INT249016 Gabrg1 Positive_regulation of Transcription of Clock 1 1 0.37 0 0.54
46 INT263738 Binding of C1ra and Neto1 1 2 0.42 0.11 0.53
47 INT305738 Binding of Creb1 and Atf6b 1 1 0.08 0.34 0.53
48 INT184922 Negative_regulation of Th Negative_regulation of da 1 1 0.12 0.18 0.52
49 INT208121 Binding of Grin2a and Grin2b 3 1 0.35 0.06 0.51
50 INT248996 Gabrg1 Negative_regulation of Gene_expression of Per2 1 1 0.33 0 0.51
51 INT249025 Gabrg1 Negative_regulation of Gene_expression of Luc7l3 1 1 0.07 0 0.51
52 INT249026 Gabrg1 Positive_regulation of Luc7l3 1 1 0.06 0 0.51
53 INT304576 Binding of Arntl and Clock 6 1 0.37 0.43 0.5
54 INT249000 Helt Negative_regulation of Per2 1 1 0.01 0 0.48
55 INT263746 Binding of Dlg4 and Neto1 1 14 0.27 0 0.48
56 INT305731 Binding of Bdnf and Creb1 Positive_regulation of BDNF 1 1 0.11 0.49 0.47
57 INT305735 Binding of Bdnf and Creb1 1 1 0.08 0.49 0.47
58 INT305747 Binding of Bdnf and Creb1 Positive_regulation of Bdnf 1 1 0.03 0.49 0.47
59 INT305746 Positive_regulation of Creb1 Positive_regulation of BDNF 1 1 0.32 0.41 0.47
60 INT305743 Binding of Bdnf and Positive_regulation of Positive_regulation of Creb1 1 1 0.11 0.49 0.47
61 INT305736 Positive_regulation of Creb1 Positive_regulation of Bdnf 1 1 0.10 0.41 0.46
62 INT249021 Gabrg1 Negative_regulation of Th 1 1 0.08 0.06 0.44
63 INT353631 Oas1a Positive_regulation of Klkb1 1 1 0.00 0 0.44
64 INT305745 Binding of Bdnf and Positive_regulation of BDNF 1 1 0.17 0.44 0.44
65 INT343642 Adp Positive_regulation of Localization of Hspg2 1 1 0.01 0 0.44
66 INT343643 Adp Positive_regulation of Positive_regulation of Hspg2 1 1 0.01 0 0.43
67 INT249011 Gabrg1 Regulation of Clock 1 1 0.19 0 0.43
68 INT250531 Ghrh Regulation of Gh 1 2 0.22 0 0.41
69 INT182479 Binding of Cxcl16 and Cxcr6 1 4 0.33 0.43 0.4
70 INT343640 Positive_regulation of Grm5 Positive_regulation of Adp 1 1 0.01 0 0.4
71 INT249004 Helt Regulation of Clock 1 1 0.01 0.09 0.37
72 INT249015 Regulation of Helt Regulation of Clock 1 1 0.01 0.09 0.37
73 INT214374 Pik3cb Regulation of Gene_expression of Slc6a3 1 1 0.37 0.3 0.35
74 INT249019 Gabrg1 Positive_regulation of Akt1 1 1 0.02 0 0.34
75 INT214377 Akt1 Regulation of Amph 1 1 0.15 0 0.33
76 INT347517 Binding of Tbxa2r and ST7L 1 3 0.00 0 0.32
77 INT198779 Binding of Dlg4 and Psd 10 10 0.25 0.09 0.31
78 INT263760 Binding of Igh-Lev and Rbm39 1 2 0.00 0 0.31
79 INT214371 Amph Positive_regulation of Ubqln1 1 1 0.01 0 0.3
80 INT263749 Binding of Grin2b and Neto1 1 4 0.38 0 0.3
81 INT214373 Negative_regulation of Amph Positive_regulation of Ubqln1 1 1 0.01 0 0.3
82 INT305739 Binding of nt and Trpv1 1 1 0.00 0.24 0.29
83 INT207823 SSTR2 Negative_regulation of Localization of GCG 1 1 0.06 0 0.29
84 INT263757 Binding of Gpx3 and Neto1 1 3 0.01 0 0.29
85 INT353632 Binding of Shbdp1 and Kncn 1 2 0.05 0 0.28
86 INT263732 Binding of Grin2a and Neto1 1 3 0.41 0 0.27
87 INT206427 Binding of HP and SULT1A3 1 1 0.03 0 0.27
88 INT305686 Binding of Gfap and F2r 1 1 0.01 0 0.25
89 INT214366 Ins1 Regulation of Slc6a3 1 1 0.11 0.09 0.25
90 INT250536 Ghrh Positive_regulation of Negative_regulation of Ptpn6 1 1 0.09 0 0.24
91 INT263787 Binding of GRIN1 and Dlg4 3 2 0.18 0.05 0.23
92 INT198776 Binding of Dlg4 and Psds1 1 7 0.11 0.05 0.23
93 INT193215 Binding of CYSLTR1 and CYSLTR2 2 2 0.09 1.7 0.21
94 INT263736 Binding of Rbm39 and Neto1 1 1 0.01 0 0.21
95 INT310497 Neurog2 Positive_regulation of Fate1 1 1 0.07 0.36 0.21
96 INT214367 Amph Positive_regulation of Localization of Ubqln1 1 1 0.01 0 0.21
97 INT263765 Neto1 Regulation of Grin1 1 2 0.39 0.26 0.2
98 INT250537 Ptpn6 Negative_regulation of Igf1 1 1 0.08 0 0.2
99 INT343641 Grm5 Positive_regulation of Adp 1 1 0.01 0 0.19
100 INT310498 Gene_expression of Neurog2 Positive_regulation of Positive_regulation of Eomes 1 1 0.20 0.42 0.19
101 INT214376 Ubqln1 Regulation of Flvcr2 1 1 0.00 0 0.19
102 INT343644 Grm5 Positive_regulation of Cav2 1 1 0.05 0 0.19
103 INT310494 Gene_expression of Dlx2 Positive_regulation of Fate1 1 1 0.04 0.1 0.18
104 INT263721 Binding of Grin1 and Neto1 1 7 0.33 0 0.18
105 INT263774 Neto1 Regulation of Insrr 1 1 0.00 0.28 0.18
106 INT347518 Regulation of Binding of Tbxa2r and ST7L 1 1 0.00 0 0.17
107 INT263769 Neto1 Regulation of Trpv1 1 1 0.00 0.27 0.17
108 INT214375 Amph Regulation of Ubqln1 1 1 0.00 0 0.16
109 INT204478 Fmr1 Regulation of Gene_expression of App 1 3 0.50 1.44 0.16
110 INT182480 Binding of Cd1d1 and Cxcr6 1 1 0.27 0.25 0.15
111 INT250533 Ghrh Regulation of Localization of Gh 1 1 0.13 0 0.15
112 INT250535 Ghrh Regulation of Gene_expression of Gh 1 1 0.31 0 0.15
113 INT182659 Positive_regulation of Gins4 Positive_regulation of Rem1 1 1 0.00 0.1 0.15
114 INT263747 Neto1 Positive_regulation of Psd 1 1 0.24 0 0.14
115 INT204497 Fmr1 Regulation of Positive_regulation of Gria1 1 1 0.04 1.75 0.14
116 INT271553 Binding of Gad2 and Gfap 1 1 0.24 0 0.13
117 INT204489 Fmr1 Regulation of App 1 1 0.50 1.71 0.13
118 INT347462 Binding of CYSLTR1 and ST7L 1 1 0.00 0.1 0.13
119 INT182478 Binding of Akt1 and Cx3cr1 1 1 0.11 0.12 0.13
120 INT206424 Binding of NFIA and ASAP1 1 1 0.33 0 0.13
121 INT263790 Binding of GRIN1 and Neto1 1 4 0.54 0 0.13
122 INT182477 Binding of Akt1 and Cxcr4 1 1 0.10 0.12 0.13
123 INT182484 Binding of Akt1 and Cxcr4 Positive_regulation of Akt1 1 1 0.06 0.12 0.13
124 INT182483 Cxcr6 Positive_regulation of Akt1 1 1 0.22 0.12 0.12
125 INT182481 Binding of Cav1 and Ighg2b 1 1 0.10 0 0.12
126 INT182482 Binding of Cav1 and Cxcl16 1 1 0.07 0 0.12
127 INT263752 Binding of Gria1 and Igh-Lev 1 1 0.00 0 0.11
128 INT347515 Binding of GP1BA and Vwf 1 1 0.01 0.19 0.11
129 INT204477 Binding of App and Scn10a 1 1 0.17 0.36 0.1
130 INT263729 Grin2b Positive_regulation of Gene_expression of Car1 1 1 0.20 0 0.1
131 INT305733 Gtf3a Positive_regulation of Gene_expression of Kcnk2 1 1 0.01 0.12 0.1
132 INT207822 ABAT Positive_regulation of Localization of GCG 1 1 0.02 0 0.1
133 INT263779 Negative_regulation of Neto1 Negative_regulation of Ltp 1 1 0.33 0 0.09
134 INT272265 Binding of Dlg4 and Grip2 1 1 0.02 0 0.09
135 INT184920 Binding of Agtrap and Slc6a3 1 1 0.02 0.09 0.09
136 INT317129 Gene_expression of Csn Positive_regulation of CASZ1 1 1 0.00 0.07 0.09
137 INT204487 Positive_regulation of Fmr1 Regulation of Gene_expression of App 1 1 0.30 0.8 0.08
138 INT263725 Neto1 Regulation of Localization of Grin1 1 1 0.39 0.15 0.08
139 INT201173 Sox2 Positive_regulation of Localization of Ryr2 1 1 0.40 0.9 0.07
140 INT263755 Grin1 Regulation of Localization of Grin2b 1 1 0.27 0.17 0.07
141 INT184827 Binding of Thy1 and Tg(CAG-EGFP)D4Nagy 1 1 0.06 0.18 0.07
142 INT263782 Grin2a Regulation of Localization of Grin1 1 1 0.29 0.17 0.07
143 INT207824 KCNJ5 Regulation of Localization of INS 1 1 0.01 0 0.07
144 INT263764 Dlg4 Regulation of Localization of Grin2a 1 1 0.16 0.17 0.07
145 INT263741 Grin2b Regulation of Localization of Dlg4 1 1 0.17 0.17 0.07
146 INT263761 Grin1 Regulation of Localization of Vamp2 1 1 0.27 0.17 0.07
147 INT263784 Dlg4 Regulation of Localization of Grin1 1 1 0.17 0.17 0.07
148 INT263748 Grin1 Regulation of Localization of Gria2 1 1 0.20 0.17 0.07
149 INT263777 Grin2a Regulation of Localization of Vamp2 1 1 0.26 0.17 0.07
150 INT263728 Grin2b Regulation of Localization of Grin1 1 1 0.27 0.17 0.07
151 INT263723 Grin2b Regulation of Localization of Gria2 1 1 0.18 0.17 0.07
152 INT263759 Grin1 Regulation of Localization of Grin2a 1 1 0.29 0.17 0.07
153 INT263734 Dlg4 Regulation of Localization of Vamp2 1 1 0.15 0.17 0.07
154 INT263742 Grin1 Regulation of Localization of Dlg4 1 1 0.19 0.17 0.07
155 INT263772 Grin2a Regulation of Localization of Gria2 1 1 0.19 0.17 0.07
156 INT263771 Grin2a Regulation of Localization of Dlg4 1 1 0.19 0.17 0.07
157 INT263762 Grin2a Regulation of Localization of Grin2b 1 1 0.26 0.17 0.07
158 INT198079 Ass1 Positive_regulation of Gene_expression of Slc1a3 1 1 0.01 0 0.07
159 INT263722 Dlg4 Regulation of Localization of Grin2b 1 1 0.15 0.17 0.07
160 INT201172 Sox2 Positive_regulation of Localization of Ca2 1 1 0.47 0.9 0.07
161 INT263739 Grin2b Regulation of Localization of Vamp2 1 1 0.24 0.17 0.07
162 INT263740 Dlg4 Regulation of Localization of Gria2 1 1 0.11 0.17 0.07
163 INT263768 Grin2b Regulation of Localization of Grin2a 1 1 0.26 0.17 0.07
164 INT305737 Binding of Sort1 and Gga2 1 2 0.19 0.11 0.06
165 INT263767 Binding of Camk2a and Grin2b 1 1 0.18 0 0.06
166 INT184917 Slc6a3 Positive_regulation of Agtrap 1 1 0.03 0.08 0.06
167 INT250538 Igf1 Positive_regulation of Gh 1 1 0.24 0.05 0.06
168 INT263724 Positive_regulation of Binding of Dlg4 and Neto1 1 2 0.28 0 0.06
169 INT184924 Ephb1 Positive_regulation of Agtrap 1 1 0.01 0.08 0.06
170 INT263743 Rasgrf1 Positive_regulation of Positive_regulation of Mapk1 1 2 0.11 0 0.06
171 INT263770 Rasgrf1 Positive_regulation of Positive_regulation of Grin1 1 2 0.24 0 0.06
172 INT248999 Binding of Per2 and Luc7l3 1 1 0.05 0 0.05
173 INT202893 Camk4 Negative_regulation of Grin1 1 1 0.10 0.17 0.05
174 INT263735 Localization of Neto1 Regulation of Localization of Vamp2 1 1 0.35 0.18 0.05
175 INT310496 Binding of Neurog2 and Mtap2 1 1 0.17 0.44 0.05
176 INT263763 Localization of Neto1 Regulation of Localization of Grin2b 1 1 0.36 0.18 0.05
177 INT263751 Binding of Dlg4 and Spna1 1 1 0.03 0 0.05
178 INT263727 Binding of Grin2b and Rasgrf1 1 2 0.18 0 0.05
179 INT263714 Binding of Dlg4 and Neto1 Positive_regulation of Binding of GRIN1 Neto1 1 1 0.34 0 0.05
180 INT263730 Binding of Grin2a and Rasgrf1 1 2 0.23 0 0.05
181 INT263780 Localization of Neto1 Regulation of Localization of Grin2a 1 1 0.38 0.18 0.05
182 INT263778 Localization of Neto1 Regulation of Localization of Dlg4 1 1 0.26 0.18 0.05
183 INT181814 Gsk3b Regulation of Gata4 1 1 0.06 0.37 0.05
184 INT263733 Localization of Neto1 Regulation of Localization of Gria2 1 1 0.26 0.18 0.05
185 INT263786 GRIN1 Regulation of Positive_regulation of Ltp 1 1 0.28 0 0.05
186 INT204387 Binding of Napa and Sds 1 2 0.00 0 0.05
187 INT263781 Localization of Neto1 Regulation of Localization of Grin1 1 1 0.39 0.18 0.05
188 INT347465 Binding of PLEK and ST7L 1 1 0.01 0 0.04
189 INT347464 Binding of WDTC1 and ST7L 1 1 0.00 0 0.04
190 INT198777 Binding of Psd and Psds1 1 2 0.05 0 0.04
191 INT185270 Binding of Fgf2 and Ifaprc2 1 1 0.08 0.4 0.04
192 INT347463 Binding of PTAFR and ST7L 1 1 0.00 0 0.04
193 INT195837 Tlr4 Positive_regulation of Pla2g4a 1 1 0.01 0.44 0.03
194 INT263783 Grin1 Positive_regulation of Mapk1 1 1 0.14 0 0.03
195 INT263788 Positive_regulation of Binding of GRIN1 and Dlg4 1 1 0.24 0 0.03
196 INT347514 Binding of CYSLTR1 and Ltc4s 1 1 0.01 0.58 0.03
197 INT195836 Tlr4 Regulation of Gene_expression of Ptges 1 1 0.00 0.52 0.03
198 INT347516 Binding of CYSLTR2 and Ltc4s 1 1 0.01 0.4 0.03
199 INT271555 Binding of Chl1 and Pkd2l1 1 1 0.16 0 0.03
200 INT195835 Tlr4 Regulation of Ptges 1 1 0.00 0.52 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 2 3152 0.78 2515.62 929.82
2 INT7114 Positive_regulation of Ltp 6 1192 0.62 290.76 755.77
3 INT1912 Gene_expression of Calca 1 1152 0.78 453.25 739.84
4 INT3439 Localization of Abat 4 1017 0.78 112.39 727.06
5 INT58061 Gene_expression of Trpv1 2 1117 0.78 451.54 637.59
6 INT443 Localization of POMC 1 1020 0.81 284.52 443.17
7 INT64202 Positive_regulation of Trpv1 3 643 0.70 249.66 397.42
8 INT467 Gene_expression of POMC 8 1048 0.78 332.8 394.16
9 INT2540 Negative_regulation of Calca 1 538 0.59 172.11 384.38
10 INT439 Localization of Gnrh1 6 976 0.81 100.96 363.25
11 INT720 Positive_regulation of POMC 3 807 0.70 237.37 353.83
12 INT5059 Positive_regulation of TNF 2 1050 0.70 896.51 322.81
13 INT5680 Gene_expression of Ngf 4 530 0.78 264.29 310.56
14 INT9659 Gene_expression of Il6 1 991 0.78 715.11 265.57
15 INT87687 Positive_regulation of Trpv1 1 409 0.70 210.24 257.59
16 INT1893 Localization of Gh 3 1041 0.79 340.23 256.58
17 INT95787 Positive_regulation of Mapk1 1 568 0.70 226.51 220.94
18 INT6481 Binding of TNF 2 624 0.48 510.2 214.82
19 INT6354 Localization of Gabrg1 7 321 0.74 41.41 186.74
20 INT49441 Negative_regulation of Cpox 2 494 0.59 303.22 177.46
21 INT7506 Negative_regulation of Ltp 8 267 0.46 91.01 176.8
22 INT1429 Gene_expression of PDYN 7 308 0.78 61.33 175.65
23 INT739 Negative_regulation of POMC 1 358 0.59 102.28 166.77
24 INT1114 Localization of Ins1 3 748 0.80 192.95 165.48
25 INT3448 Positive_regulation of Gh 1 521 0.69 180.03 161.18
26 INT7628 Gene_expression of Ltp 7 273 0.77 70.21 147.87
27 INT1033 Positive_regulation of Ca2 29 507 0.68 131.76 147.64
28 INT9852 Positive_regulation of Gpt 1 563 0.70 364.64 146.82
29 INT812 Localization of INS 31 1026 0.81 515.6 145.31
30 INT14843 Gene_expression of Gabrg1 19 301 0.77 62.63 139.16
31 INT1047 Negative_regulation of LH 2 314 0.59 53.71 135.89
32 INT49439 Gene_expression of Cpox 1 508 0.73 326.97 130.17
33 INT115386 Gene_expression of Ppara 2 779 0.77 549.99 128.36
34 INT65600 Positive_regulation of Casp3 1 376 0.70 198.44 128.03
35 INT5842 Gene_expression of Gfap 1 372 0.78 153.71 127.71
36 INT6323 Positive_regulation of Gabrg1 8 213 0.70 45.08 124.34
37 INT6128 Positive_regulation of Localization of POMC 1 256 0.70 68.77 121.64
38 INT7533 Gene_expression of Tlr4 1 720 0.78 343.22 121.57
39 INT64201 Negative_regulation of Trpv1 1 203 0.59 79.18 119.75
40 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 53 1138 0.72 311.58 119.18
41 INT1530 Regulation of Gh 2 382 0.61 115.96 112.47
42 INT65731 Gene_expression of Cnr1 40 234 0.78 63.82 109.34
43 INT89054 Positive_regulation of Gene_expression of Trpv1 1 156 0.70 90.78 102.03
44 INT65500 Gene_expression of App 28 605 0.78 429.94 98.31
45 INT4822 Localization of Ca2 33 417 0.80 99.57 96.45
46 INT3537 Positive_regulation of Car2 14 413 0.56 103.51 94.35
47 INT9516 Negative_regulation of Gabrg1 9 149 0.53 27.83 91.02
48 INT38731 Localization of Trpv1 1 138 0.81 52.73 90.49
49 INT1160 Positive_regulation of Rbm39 1 122 0.57 28.19 90.28
50 INT1472 Positive_regulation of Ins1 1 349 0.69 146.2 86.36
51 INT21793 Positive_regulation of Ngf 1 154 0.70 94.78 85.27
52 INT2520 Negative_regulation of Ca2 13 271 0.57 72.13 83.71
53 INT8534 Localization of Pax3 1 85 0.59 28.71 82.82
54 INT1498 Gene_expression of Gh 12 521 0.75 220.84 81.16
55 INT92518 Gene_expression of Grin2b 8 131 0.78 65.52 80.91
56 INT12476 Negative_regulation of TRPV1 1 124 0.59 47.95 77.98
57 INT3657 Gene_expression of Ins1 5 514 0.78 321.69 75.76
58 INT25363 Negative_regulation of Trpv1 2 144 0.59 64.78 75.7
59 INT16654 Gene_expression of Insrr 1 138 0.46 58.96 75.68
60 INT98621 Regulation of Trpv1 4 121 0.62 79.24 75.23
61 INT1497 Negative_regulation of Gh 7 415 0.59 192.95 74.71
62 INT442 Localization of PDYN 1 99 0.81 11.87 72.75
63 INT57380 Phosphorylation of Creb1 4 213 0.82 66.8 71.26
64 INT14049 Positive_regulation of GRIN1 2 102 0.70 48.31 71.06
65 INT14624 Gene_expression of Pax3 1 100 0.38 33.22 69.47
66 INT13276 Regulation of Ltp 2 107 0.53 30.78 69.13
67 INT2123 Positive_regulation of Gnrh1 1 209 0.70 24.2 68.97
68 INT1988 Positive_regulation of Localization of Ins1 2 254 0.69 59.25 68.37
69 INT5374 Gene_expression of Esr1 2 412 0.77 263.89 67.34
70 INT65733 Positive_regulation of Cnr1 7 125 0.70 40.27 67.33
71 INT13286 Gene_expression of Ca2 18 317 0.67 71.58 65.01
72 INT2056 Negative_regulation of Gnrh1 1 175 0.59 33.43 63.32
73 INT3950 Gene_expression of Ptger2 25 293 0.77 122.28 62.42
74 INT12175 Positive_regulation of PDYN 4 86 0.69 18.27 62.04
75 INT18981 Gene_expression of ABAT 1 78 0.68 38.35 61.36
76 INT11318 Gene_expression of Gtf3a 10 274 0.52 183.82 60.89
77 INT2761 Regulation of Gabrg1 3 119 0.61 18.8 60.52
78 INT17564 Gene_expression of Gpt 3 322 0.75 208.51 60.36
79 INT103924 Positive_regulation of Akt1 1 359 0.69 158.94 60.34
80 INT1430 Regulation of PDYN 3 88 0.60 16.99 60.32
81 INT1536 Negative_regulation of NA 7 244 0.55 52.67 59.79
82 INT102020 Gene_expression of Creb1 6 190 0.78 57.31 59.77
83 INT6623 Gene_expression of NA 2 231 0.78 45.78 59.36
84 INT3920 Localization of Ldha 5 241 0.81 83.08 58.72
85 INT82055 Positive_regulation of Creb1 12 176 0.70 60.2 58.39
86 INT4509 Gene_expression of IGG 1 426 0.76 293.69 56.64
87 INT1200 Negative_regulation of Ins1 6 274 0.58 155.17 56.14
88 INT31186 Negative_regulation of Insrr 1 81 0.37 24.91 55.94
89 INT31186 Negative_regulation of Insrr 1 81 0.37 24.91 55.94
90 INT119528 Positive_regulation of Camk2a 1 135 0.70 26.13 54.7
91 INT117713 Phosphorylation of Akt1 3 275 0.82 95.82 54.34
92 INT2276 Regulation of Ins1 1 234 0.61 103.78 54.05
93 INT1032 Regulation of Ca2 3 202 0.52 54.91 53.03
94 INT1487 Regulation of Cpe 1 68 0.62 10.24 52.91
95 INT72182 Gene_expression of Mcpt1 1 167 0.75 123.7 52.15
96 INT6034 Binding of Gabrg1 2 115 0.47 17.48 51.92
97 INT66040 Positive_regulation of Bdnf 1 114 0.69 67.67 51.81
98 INT50334 Negative_regulation of Cnr1 5 84 0.58 30.86 51.75
99 INT122041 Binding of Ppara 2 308 0.48 189.17 51.48
100 INT5136 Negative_regulation of PDYN 2 71 0.59 11.22 51.14
101 INT2197 Gene_expression of Gnrh1 4 184 0.78 40.04 50.57
102 INT1199 Positive_regulation of INS 1 579 0.70 399.64 50.43
103 INT35975 Regulation of Cpox 1 109 0.39 57.88 49.69
104 INT40777 Positive_regulation of Akt1 5 163 0.69 59.41 49.43
105 INT55671 Gene_expression of Ik 1 151 0.27 80.1 48.49
106 INT12471 Regulation of Insrr 1 52 0.35 17.8 48.31
107 INT62426 Gene_expression of Mc1r 14 127 0.78 42.99 48.01
108 INT16850 Negative_regulation of Localization of Gabrg1 2 73 0.51 8.28 47.89
109 INT30170 Gene_expression of Car2 10 330 0.66 77.26 46.76
110 INT1322 Positive_regulation of Localization of INS 6 293 0.70 120.86 45.98
111 INT2783 Gene_expression of Slc3a1 7 86 0.65 8.84 45.4
112 INT6979 Positive_regulation of CA2 2 206 0.67 50.79 44.97
113 INT2275 Negative_regulation of Localization of Ins1 2 183 0.59 51.02 44.94
114 INT1726 Positive_regulation of Kitl 1 65 0.70 38.81 44.85
115 INT3361 Positive_regulation of Esr1 5 273 0.69 208.53 44.81
116 INT63383 Binding of Cnr1 2 77 0.48 22.28 44.61
117 INT17561 Localization of Car2 17 303 0.79 60.95 44.52
118 INT98498 Binding of Trpv1 1 75 0.48 33.67 44.4
119 INT19078 Binding of Ngf 1 78 0.48 31.03 44.33
120 INT66383 Phosphorylation of Prkaca 1 143 0.80 30.85 43.38
121 INT94029 Positive_regulation of Grin2b 2 58 0.70 24.2 42.52
122 INT5130 Regulation of GNRH1 1 139 0.62 31.95 42.08
123 INT60388 Gene_expression of Helt 1 90 0.07 19.18 41.72
124 INT4887 Gene_expression of Tac4 1 70 0.77 11.66 40.97
125 INT92517 Gene_expression of Grin1 19 105 0.78 29.53 39.43
126 INT6357 Positive_regulation of Localization of Gabrg1 1 53 0.41 7.03 39.21
127 INT92515 Gene_expression of Grin2a 10 84 0.76 26.68 38.37
128 INT30817 Gene_expression of Th 4 142 0.76 33.56 38.12
129 INT4449 Positive_regulation of NA 2 179 0.55 40.26 37.82
130 INT14009 Gene_expression of Sst 1 66 0.77 19.6 37.3
131 INT81037 Negative_regulation of Slc6a3 4 70 0.59 15.31 37.01
132 INT3253 Negative_regulation of Localization of INS 7 205 0.59 130.39 36.61
133 INT12029 Gene_expression of Car1 1 143 0.67 29.69 36.39
134 INT316 Regulation of Cebpz 5 105 0.00 27.21 35.41
135 INT2274 Regulation of Localization of INS 4 101 0.62 41.55 34.79
136 INT52194 Positive_regulation of Grin1 6 83 0.69 25.09 34.76
137 INT1163 Negative_regulation of Rbm39 3 64 0.29 16.8 34.74
138 INT66005 Regulation of Cnr1 3 47 0.61 19.21 34.52
139 INT14559 Gene_expression of Igf1 25 254 0.78 112 34.17
140 INT17381 Gene_expression of Tbxa2r 8 146 0.78 65.01 34.15
141 INT49214 Gene_expression of Cd4 1 269 0.78 154.22 34.05
142 INT95789 Positive_regulation of Grm5 25 42 0.55 20.1 33.72
143 INT5489 Localization of CA2 2 172 0.80 39.46 33.56
144 INT234 Binding of Alb 3 151 0.48 52.34 32.97
145 INT29743 Negative_regulation of App 1 91 0.59 65.56 31.26
146 INT56809 Binding of Tlr4 3 184 0.48 106.02 31.18
147 INT8531 Transcription of PDYN 3 56 0.72 19.51 30.99
148 INT11650 Negative_regulation of Gpt 2 122 0.59 69.15 30.36
149 INT57379 Positive_regulation of Phosphorylation of Creb1 1 79 0.69 28.24 30.25
150 INT64918 Gene_expression of Gria2 2 108 0.74 29.95 29.67
151 INT72252 Gene_expression of Kcnma1 2 63 0.64 20.47 29.56
152 INT67912 Gene_expression of GRIN1 3 75 0.77 28.99 29.28
153 INT15174 Gene_expression of Itgam 2 238 0.73 104.92 29.26
154 INT11796 Positive_regulation of Helt 2 52 0.31 11.7 29.22
155 INT5440 Negative_regulation of Ina 8 85 0.58 10.52 28.98
156 INT47712 Positive_regulation of App 16 135 0.69 101.38 28.94
157 INT2532 Negative_regulation of Cebpz 1 98 0.00 53.06 28.57
158 INT66200 Gene_expression of Gfap 16 215 0.78 88.04 28.25
159 INT154007 Gene_expression of da 40 46 0.56 15.28 28.22
160 INT154007 Gene_expression of da 1 46 0.56 15.28 28.22
161 INT17825 Gene_expression of Flvcr2 2 44 0.68 12.58 28.08
162 INT6584 Negative_regulation of Pax3 1 31 0.39 14.64 27.97
163 INT112707 Negative_regulation of Akt1 5 89 0.59 28.85 27.76
164 INT6174 Regulation of Gene_expression of POMC 2 49 0.61 9.75 27.69
165 INT37296 Binding of Esr1 1 117 0.43 62.51 27.33
166 INT123035 Gene_expression of Ephb1 1 38 0.78 28.84 27.32
167 INT123035 Gene_expression of Ephb1 1 38 0.78 28.84 27.32
168 INT3217 Regulation of Ins1 1 154 0.62 87.11 27.29
169 INT145426 Positive_regulation of Ros1 1 185 0.56 106.76 27.21
170 INT54467 Localization of Ltp 1 41 0.58 8.86 26.88
171 INT56053 Negative_regulation of Bdnf 1 77 0.58 64.4 26.83
172 INT32826 Positive_regulation of Gene_expression of Ltp 2 52 0.45 10.34 26.8
173 INT22764 Localization of Ptger2 2 81 0.64 24.38 26.77
174 INT16428 Positive_regulation of Gtf3a 2 135 0.20 106.44 26.67
175 INT93360 Gene_expression of Slc6a3 6 63 0.78 19.54 26.55
176 INT2261 Gene_expression of Lhb 1 121 0.77 42.78 26.04
177 INT80791 Gene_expression of Slc6a3 17 113 0.78 11.89 25.76
178 INT89662 Positive_regulation of Gene_expression of App 4 169 0.70 133.36 25.62
179 INT61664 Regulation of GRIN1 1 38 0.60 16.45 25.35
180 INT101483 Gene_expression of Lep 2 159 0.78 104.77 25.12
181 INT17625 Localization of GCG 108 210 0.80 55.69 24.97
182 INT107577 Negative_regulation of Grin2b 1 32 0.59 12.35 24.88
183 INT23937 Gene_expression of EDNRA 1 103 0.65 55.63 24.67
184 INT40776 Gene_expression of Akt1 6 99 0.77 34.91 24.39
185 INT64076 Positive_regulation of Kcnma1 4 47 0.40 11.52 24.19
186 INT72370 Gene_expression of Timp1 2 82 0.65 57.52 24.16
187 INT14556 Positive_regulation of Igf1 2 105 0.69 52.21 24.04
188 INT13838 Positive_regulation of Drd1a 1 48 0.70 9.83 23.42
189 INT102021 Positive_regulation of Gene_expression of Creb1 2 66 0.70 24.04 23.28
190 INT55251 Gene_expression of a 22 142 0.67 81.21 23.03
191 INT76249 Gene_expression of Gria1 1 67 0.75 15.07 22.78
192 INT91891 Gene_expression of Kit 1 268 0.78 158.89 22.67
193 INT20575 Gene_expression of Akr1d1 7 48 0.57 6.2 22.5
194 INT4369 Gene_expression of Ldha 2 157 0.76 88.12 22.45
195 INT127435 Gene_expression of Per1 2 89 0.77 13.94 22.31
196 INT16851 Regulation of Localization of Gabrg1 1 34 0.39 4.34 22.29
197 INT11893 Positive_regulation of Ptger2 7 96 0.69 31.49 21.92
198 INT23564 Negative_regulation of Car2 5 103 0.50 27.28 21.86
199 INT4890 Gene_expression of Ppt1 2 51 0.77 8.93 21.83
200 INT78057 Localization of Tlr4 2 140 0.77 67.75 21.72
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