J:PLoS Genetics

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT236491 GCH1 Regulation of Pain1 1 1 0.01 0.89 1.65
2 INT348175 Binding of NIDDM1 and PTPN22 1 1 0.01 2.36 0.99
3 INT201614 Mc1r Regulation of Uvbi1 1 2 0.04 1.42 0.98
4 INT271511 Binding of Phb2 and Glrb 1 1 0.04 1.7 0.84
5 INT309001 Ins1 Positive_regulation of Mmp9 1 2 0.20 1.96 0.83
6 INT348174 Binding of STAT3 and IL23R 1 2 0.40 1.9 0.76
7 INT252145 Binding of Napb and Snap25 9 8 0.19 0.85 0.75
8 INT236489 Gtf3a Regulation of Pain1 1 1 0.00 0.52 0.56
9 INT236492 Gtf3a Regulation of SNRNP70 1 1 0.00 0.52 0.56
10 INT348173 Binding of HLA-B and IL23R 1 1 0.15 0.92 0.49
11 INT348177 Binding of HLA-B and ERAP1 1 1 0.14 0.92 0.49
12 INT201610 Binding of Mc1r and Braf 1 1 0.31 0.75 0.42
13 INT198536 Cox11 Negative_regulation of HK1 1 6 0.22 0.08 0.41
14 INT326942 Unc79 Regulation of Nalcn 1 1 0.20 0.08 0.41
15 INT146611 Ins1 Positive_regulation of Phosphorylation of Akt1 9 1 0.23 4.34 0.37
16 INT309003 Ins1 Positive_regulation of TNF 1 1 0.05 1.74 0.35
17 INT279705 CALM3 Regulation of TRPV4 2 1 0.08 0 0.33
18 INT206208 MRO Negative_regulation of CD24 1 2 0.02 1.87 0.32
19 INT227339 Binding of TNF and Ins1 1 2 0.28 4.08 0.31
20 INT252140 Binding of Cck and Snap25 1 1 0.30 0.39 0.3
21 INT258861 Binding of HLA-DOA and HLA-DRB1 2 1 0.14 1.88 0.28
22 INT216127 EGR1 Regulation of Transcription of TP53 1 1 0.06 0.21 0.28
23 INT216128 EGR1 Regulation of TP53 1 1 0.11 0.21 0.27
24 INT279828 Binding of Scn1a and Scn9a 1 1 0.39 1.64 0.26
25 INT277317 Binding of Celf1 and Slc6a11 1 1 0.19 0.06 0.26
26 INT198538 Binding of HK1 and Cox11 1 1 0.14 0 0.24
27 INT326941 Nts Regulation of Nalcn 1 1 0.04 0.24 0.23
28 INT309000 Ins1 Positive_regulation of Gene_expression of Mmp9 1 1 0.20 1.03 0.22
29 INT309002 Ins1 Positive_regulation of Positive_regulation of Mmp9 1 1 0.20 1.03 0.22
30 INT277318 Upf1 Positive_regulation of Atxn8os 1 2 0.01 0.77 0.21
31 INT326940 Chrm3 Positive_regulation of Nalcn 1 1 0.06 0.21 0.19
32 INT198523 Ranbp2 Negative_regulation of Cox11 1 1 0.42 0 0.17
33 INT198540 Ranbp2 Negative_regulation of HK1 1 2 0.19 0 0.17
34 INT289625 Binding of RS1 and PSORS1C1 1 1 0.02 1.15 0.17
35 INT289630 Binding of CDSN and RS1 1 1 0.02 1.1 0.17
36 INT201609 Uvbi1 Positive_regulation of Gene_expression of Mc1r 1 2 0.05 0.57 0.17
37 INT201608 Binding of Mc1r and Uvbi1 1 5 0.03 0.93 0.15
38 INT206212 UTS2R Positive_regulation of CD24 1 1 0.09 0.71 0.15
39 INT201622 Binding of Mark3 and Mc1r 1 2 0.33 0.74 0.15
40 INT201619 Binding of Cdk11b and Mc1r 1 2 0.28 0.74 0.15
41 INT279829 Scn1a Regulation of Gene_expression of Scn9a 1 1 0.42 1.52 0.15
42 INT314856 Binding of Cdc7 and Cdkn2a 1 3 0.28 1.34 0.14
43 INT314867 Binding of Cdc7 and Cdkn2b 1 1 0.25 1.16 0.14
44 INT314852 Binding of Cdkn2a and Tgfbr3 1 1 0.28 1.15 0.14
45 INT206209 MRO Negative_regulation of Transcription of CD24 1 1 0.02 0.76 0.14
46 INT314859 Binding of Cdkn2b and Tgfbr3 1 1 0.33 1.16 0.14
47 INT271513 Binding of Glrb and Spha2 1 2 0.16 0.18 0.13
48 INT236588 Binding of Esr1 and Ins1 1 1 0.05 0.73 0.12
49 INT289624 HLA-DMB Regulation of Binding of RS1 1 1 0.03 0.84 0.11
50 INT289629 Binding of HLA-DMB and HLA-E 1 1 0.10 0.84 0.11
51 INT289627 Binding of HLA-E and RS1 1 1 0.01 0.83 0.11
52 INT289623 Binding of HLA-E and RS1 Regulation of Binding of RS1 1 1 0.00 0.84 0.11
53 INT289622 Binding of HLA-DMB and HLA-E Regulation of Binding of RS1 1 1 0.01 0.84 0.11
54 INT198525 Binding of Kif5b and Ranbp2 1 1 0.23 0 0.1
55 INT213421 Binding of CXCL2 and SET 1 1 0.11 0.17 0.1
56 INT213417 Binding of CCL7 and SET 1 1 0.11 0.17 0.1
57 INT213414 Binding of CXCL1 and SET 1 1 0.10 0.17 0.1
58 INT213415 Binding of CCL8 and SET 1 1 0.11 0.17 0.1
59 INT213420 Binding of IL6 and SET 1 1 0.10 0.17 0.1
60 INT303815 Binding of Igfals and Tdp1 1 1 0.11 1.68 0.1
61 INT213416 Binding of CCL2 and SET 1 1 0.11 0.17 0.1
62 INT277316 Upf1 Positive_regulation of Slc6a11 1 2 0.01 0.47 0.09
63 INT279707 Positive_regulation of AGTR1 Regulation of TYRP1 1 1 0.00 0 0.09
64 INT201618 Uvbi1 Positive_regulation of Phb 1 1 0.04 0.28 0.09
65 INT279706 Positive_regulation of AGTR1 Regulation of TRPC6 1 1 0.00 0 0.09
66 INT277320 Upf1 Positive_regulation of Upf1 Positive_regulation of Slc6a11 1 2 0.00 0.47 0.09
67 INT213418 Negative_regulation of FOXF1 Negative_regulation of Gene_expression of VCAM1 1 1 0.29 0.15 0.08
68 INT201615 Binding of Mark3 and Uvbi1 1 1 0.03 0.36 0.08
69 INT277319 Gene_expression of Celf1 Positive_regulation of Positive_regulation of Slc6a11 1 1 0.24 0.08 0.08
70 INT201621 Binding of Cdk11b and Uvbi1 1 1 0.02 0.36 0.08
71 INT201616 Uvbi1 Positive_regulation of Mark3 1 1 0.03 0.36 0.08
72 INT277313 Negative_regulation of Mbnl1 Positive_regulation of Positive_regulation of Slc6a11 1 1 0.52 0.08 0.08
73 INT201611 Uvbi1 Negative_regulation of Bop1 1 1 0.03 0.3 0.08
74 INT201613 Uvbi1 Positive_regulation of Cdk11b 1 1 0.03 0.36 0.08
75 INT272774 Binding of Mc4r and Fto 1 1 0.30 0.66 0.08
76 INT213419 Negative_regulation of FOXF1 Negative_regulation of Gene_expression of HGF 1 1 0.25 0.15 0.08
77 INT227836 Binding of ERCC6 and GPER 1 5 0.21 0.27 0.08
78 INT216130 SRF Positive_regulation of Gene_expression of EGR1 1 1 0.49 0.32 0.07
79 INT216129 SRF Positive_regulation of Gene_expression of FOS 1 1 0.28 0.32 0.07
80 INT252141 Binding of Snap25 and Spata20 1 1 0.01 0 0.07
81 INT271512 Binding of Glrb and Traf1 1 1 0.09 0.1 0.05
82 INT279889 Il6 Regulation of Socs3 1 1 0.21 0.17 0.05
83 INT271510 Binding of Glrb and rs 1 2 0.00 0.26 0.05
84 INT198530 Ranbp2 Negative_regulation of Ranbp2 Negative_regulation of HK1 1 1 0.22 0 0.05
85 INT236591 Binding of Esr1 and Positive_regulation of Tmed4 1 1 0.04 0.52 0.05
86 INT279907 Binding of GCLM and IRF8 1 1 0.22 0.82 0.05
87 INT279902 Binding of GCLM and CARD8 1 1 0.28 0.82 0.05
88 INT279896 Binding of GCLM and STX6 1 1 0.24 0.82 0.05
89 INT225493 Binding of Esr1 and Pprc1 2 1 0.01 0.17 0.04
90 INT220812 Tert Positive_regulation of Gene_expression of hl 1 1 0.01 0.14 0.04
91 INT279895 Binding of ABCC6 and USF1 1 1 0.31 0.8 0.04
92 INT287613 Binding of Fmr1 and Cysltr1 1 1 0.01 0.18 0.04
93 INT198533 Ranbp2 Regulation of HK1 1 1 0.12 0.06 0.04
94 INT236596 Ncoa2 Positive_regulation of PELP1 1 1 0.36 0.17 0.04
95 INT220811 Tert Positive_regulation of Gene_expression of Krt36 1 1 0.41 0.14 0.04
96 INT236595 Binding of Esr1 and PELP1 1 1 0.27 0.17 0.04
97 INT279899 Binding of HSD11B1 and USF1 1 1 0.31 0.79 0.04
98 INT279903 Binding of EMR1 and USF1 1 3 0.01 2.24 0.04
99 INT220808 Tert Positive_regulation of Gene_expression of Krt31 1 1 0.43 0.14 0.04
100 INT198537 Binding of HK1 and Ranbp2 1 3 0.22 0.05 0.04
101 INT198542 Cox11 Regulation of HK1 1 2 0.13 0.06 0.04
102 INT198524 Cox11 Negative_regulation of Ranbp2 1 1 0.19 0.08 0.04
103 INT236586 Binding of Ncoa2 and Psmd4 1 1 0.12 0.22 0.03
104 INT251963 Binding of HSD11B1 and LIPC 1 1 0.15 0.35 0.03
105 INT236590 Binding of Adipoq and Ncoa2 1 1 0.15 0.2 0.03
106 INT336765 Binding of FLT1 and ERAP2 1 1 0.30 0.58 0.03
107 INT213422 MITF Negative_regulation of PROC 1 1 0.00 0.52 0.03
108 INT206207 Binding of SLEB1 and CD24 1 1 0.03 0.87 0.03
109 INT277243 Camk4 Regulation of Regulation of aicda 1 1 0.04 0.42 0.03
110 INT236597 Ncoa1 Positive_regulation of PELP1 1 1 0.41 0.17 0.03
111 INT236587 Binding of Adipoq and Ncoa1 1 1 0.17 0.2 0.03
112 INT206211 MRO Regulation of Negative_regulation of CD24 1 1 0.01 0.1 0.03
113 INT277223 Trib3 Regulation of Regulation of aicda 1 1 0.01 0.42 0.03
114 INT236592 Positive_regulation of Binding of Adipoq and Ncoa2 1 1 0.19 0.2 0.03
115 INT236585 Ncoa2 Positive_regulation of Transcription of Ncoa1 1 1 0.27 0.23 0.03
116 INT289626 Binding of SNRNP70 and SUGT1 3 2 0.03 2.49 0
117 INT249159 HSPG2 Positive_regulation of Gene_expression of ITPR3 2 1 0.01 0.06 0
118 INT251961 Binding of LDLR and SNRNP70 2 1 0.04 0.55 0
119 INT247442 Binding of HSD11B1 and SNRNP70 2 1 0.04 1.3 0
120 INT279885 Ctcf Regulation of H19 1 1 0.12 0 0
121 INT314869 Binding of Gdf11 and Tgfbr3 1 1 0.29 0.14 0
122 INT287620 Fmr1 Regulation of Gene_expression of Fxr2 1 1 0.43 0 0
123 INT324347 Binding of UMOD and Scr 1 3 0.20 2.23 0
124 INT227830 CSH1 Regulation of ERCC6 1 1 0.11 0 0
125 INT230711 Binding of Sqle and Gbgt1 1 1 0.01 0 0
126 INT189929 Lox Positive_regulation of Pol 1 1 0.02 0.34 0
127 INT324342 UMOD Positive_regulation of Scr 1 1 0.17 1.29 0
128 INT287609 Fmr1 Regulation of Protein_catabolism of Dlg4 1 1 0.05 0.06 0
129 INT314865 Binding of Ltbp3 and Tgfb1 1 1 0.24 0.51 0
130 INT213868 ERF Regulation of Gene_expression of Pomc 1 1 0.01 0.08 0
131 INT279704 Binding of CIB1 and Positive_regulation of ITPR3 1 2 0.06 0.17 0
132 INT314863 Binding of Neurod1 and Atoh7 1 1 0.18 0.27 0
133 INT279905 Binding of SNRNP70 and TGS1 1 2 0.01 1.85 0
134 INT201620 Binding of Kit and Uvbi1 1 3 0.03 0.2 0
135 INT200211 Gh Positive_regulation of Localization of Igf1 1 2 0.38 2.05 0
136 INT314850 Shh Regulation of Atoh7 1 1 0.45 0.22 0
137 INT227837 Positive_regulation of Binding of CSH1 and ERCC6 1 1 0.20 0.15 0
138 INT279900 Binding of RS1 and TGS1 1 1 0.00 1.12 0
139 INT324312 Binding of GATM and UMOD 1 1 0.02 1.62 0
140 INT220818 Binding of Ctnnb1 and Myc 1 1 0.06 0.13 0
141 INT336764 ERAP2 Regulation of Gene_expression of HLA-E 1 1 0.24 0 0
142 INT198541 Ranbp2 Positive_regulation of Binding of HK1 1 1 0.22 0 0
143 INT279901 Binding of FADS3 and USF1 1 5 0.35 4.71 0
144 INT324306 Binding of GATM and STC1 1 1 0.02 1.61 0
145 INT314858 Binding of Gdf11 and Ltbp3 1 2 0.39 0.31 0
146 INT314854 Gdf11 Regulation of Atoh7 1 1 0.51 0.21 0
147 INT279891 Shbdp1 Negative_regulation of PCDHB@ 1 1 0.01 0.09 0
148 INT288983 Binding of DEFB1 and HPR 1 1 0.01 0 0
149 INT314871 Binding of Tgfbr3 and Atoh7 1 1 0.33 0.09 0
150 INT277555 Clrn1 Regulation of Localization of Pdc 1 1 0.05 0.7 0
151 INT252143 Bdnf Regulation of Gene_expression of Npy 1 1 0.11 0.49 0
152 INT287612 Binding of Fmr1 and Dnajc13 1 1 0.01 0.84 0
153 INT277315 Binding of Insr and Mbnl1 1 1 0.18 1.1 0
154 INT227829 CFC1 Positive_regulation of Gene_expression of ERCC6 1 1 0.03 0 0
155 INT314855 Binding of Gdf11 and Atoh7 1 1 0.40 0.14 0
156 INT324346 Regulation of UMOD Positive_regulation of Scr 1 1 0.10 1.31 0
157 INT220819 Myc Regulation of Transcription of Tert 1 1 0.44 0.1 0
158 INT227838 Binding of ERCC6 and PGBD3 1 2 0.40 0.23 0
159 INT329013 Binding of LITAF and Nedd4 1 2 0.15 1.4 0
160 INT314862 Binding of Ltbp3 and Tgfb2 1 1 0.24 0.52 0
161 INT198535 Positive_regulation of HK1 Positive_regulation of Cox11 1 1 0.19 0 0
162 INT303822 Tdp1 Regulation of TREH 1 1 0.02 0.92 0
163 INT279904 Binding of FADS3 and RS1 1 1 0.00 1.12 0
164 INT220813 Tert Positive_regulation of Terc 1 2 0.51 0.17 0
165 INT239913 Binding of C7 and C8B 1 1 0.18 0.06 0
166 INT329004 Binding of MPZ and RNF123 1 1 0.00 0.7 0
167 INT332136 POGLUT1 Negative_regulation of HJURP 1 1 0.00 0.06 0
168 INT336780 Ighmbp2 Regulation of ERAP2 1 1 0.02 0.15 0
169 INT279886 Shbdp1 Negative_regulation of Pcdhb1 1 1 0.10 0.09 0
170 INT324343 SLC12A1 Regulation of Scr 1 1 0.00 0.25 0
171 INT279894 Binding of USF1 and TGS1 1 4 0.11 3.52 0
172 INT314868 Binding of Ltbp2 and Ltbp3 1 1 0.29 0.54 0
173 INT220817 Tert Regulation of hl 1 2 0.01 0.96 0
174 INT279898 SNRNP70 Regulation of EMR1 1 1 0.00 0.93 0
175 INT288982 Binding of CD79A and SFTPA2 1 1 0.00 0.06 0
176 INT332135 POGLUT1 Negative_regulation of NLRP5 1 1 0.00 0.06 0
177 INT198539 Negative_regulation of Cox11 Negative_regulation of HK1 1 1 0.16 0 0
178 INT198527 Binding of Ranbp2 and Cox11 1 2 0.47 0 0
179 INT324305 Binding of CST3 and UMOD 1 2 0.05 3.22 0
180 INT287606 Binding of Fxr1 and Fxr2 1 1 0.32 0 0
181 INT314851 Positive_regulation of Binding of Neurod1 and Atoh7 1 1 0.23 0.27 0
182 INT277311 Mbnl1 Regulation of Gene_expression of Slc6a11 1 1 0.50 0.06 0
183 INT227832 Binding of CSH1 and ERCC6 1 1 0.15 0.15 0
184 INT227841 PGBD1 Positive_regulation of ERCC6 1 1 0.44 0.29 0
185 INT336766 Binding of CD19 and HLA-A Regulation of HLA-A 1 1 0.00 0 0
186 INT251962 Binding of HSD11B1 and RS1 1 1 0.00 0.33 0
187 INT332069 POGLUT1 Negative_regulation of fd 1 1 0.00 0.06 0
188 INT329012 Binding of MPZ and Nedd4 1 1 0.03 0.7 0
189 INT314866 Binding of Six1 and Sall1 1 1 0.39 0.76 0
190 INT287605 Binding of Fmr1 and Kdm5d 1 1 0.01 0 0
191 INT230712 Binding of Mnat1 and Ccnh 1 1 0.34 0.09 0
192 INT324313 Binding of STC1 and UMOD 1 2 0.29 3.22 0
193 INT279884 Nipbl Regulation of Transcription of Pcdhb1 1 1 0.25 0.05 0
194 INT287610 Binding of Fmr1 and Fxr1 1 3 0.46 0 0
195 INT287616 Ap3b1 Regulation of Binding of Fmr1 1 1 0.01 0 0
196 INT324311 Binding of UMOD and SHROOM3 1 1 0.29 1.62 0
197 INT220821 Binding of MAX and Ctnnb1 1 1 0.09 0.13 0
198 INT287611 Fmr1 Regulation of Gene_expression of Fxr1 1 1 0.38 0 0
199 INT314870 Binding of Ltbp3 and Tgfb3 1 1 0.24 0.52 0
200 INT279892 Shbdp1 Negative_regulation of Gene_expression of PCDHB@ 1 1 0.01 0.09 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 8 3152 0.78 2515.62 929.82
2 INT9238 Gene_expression of IL6 1 1575 0.78 1135.66 424.22
3 INT467 Gene_expression of POMC 5 1048 0.78 332.8 394.16
4 INT18357 Gene_expression of TRPV1 1 825 0.78 307.11 382.81
5 INT5059 Positive_regulation of TNF 7 1050 0.70 896.51 322.81
6 INT5379 Gene_expression of Fos 5 656 0.78 255.5 292.54
7 INT9381 Positive_regulation of TRPV1 1 523 0.70 187.4 276.05
8 INT94450 Gene_expression of Nav1 1 359 0.78 131.85 275.46
9 INT9659 Gene_expression of Il6 1 991 0.78 715.11 265.57
10 INT1893 Localization of Gh 3 1041 0.79 340.23 256.58
11 INT16868 Gene_expression of Il6 1 807 0.78 499.48 256.57
12 INT11009 Phosphorylation of Creb1 3 458 0.82 111.34 221.97
13 INT6665 Gene_expression of FOS 1 520 0.77 165.31 217.66
14 INT6481 Binding of TNF 2 624 0.48 510.2 214.82
15 INT6482 Positive_regulation of Gene_expression of TNF 4 659 0.70 569.88 210
16 INT49441 Negative_regulation of Cpox 2 494 0.59 303.22 177.46
17 INT55879 Gene_expression of CCL2 2 421 0.78 240.74 166.02
18 INT2640 Gene_expression of Pomc 15 424 0.78 120.72 155.37
19 INT14843 Gene_expression of Gabrg1 2 301 0.77 62.63 139.16
20 INT5380 Positive_regulation of Gene_expression of Fos 1 243 0.70 105.65 131.05
21 INT1878 Binding of HLA-B 1 440 0.48 321.16 127.36
22 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 5 1138 0.72 311.58 119.18
23 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 4 1138 0.72 311.58 119.18
24 INT17612 Gene_expression of CRP 2 676 0.78 580.61 119.03
25 INT9235 Negative_regulation of Gene_expression of TNF 2 346 0.59 252.98 118.61
26 INT92669 Gene_expression of Bdnf 4 309 0.78 178.26 116.68
27 INT1438 Localization of Pomc 1 360 0.81 101.26 116.47
28 INT11011 Positive_regulation of Phosphorylation of Creb1 1 190 0.70 49.25 112.01
29 INT3038 Gene_expression of INS 1 1583 0.78 1174.16 107.01
30 INT69440 Gene_expression of ROS1 1 752 0.78 477.64 103.83
31 INT18009 Positive_regulation of CRP 2 518 0.70 553.03 103.74
32 INT10272 Gene_expression of Il1b 3 194 0.78 121.02 103.03
33 INT10838 Positive_regulation of IL8 2 381 0.70 295.51 101.62
34 INT7944 Positive_regulation of Fos 1 193 0.70 60.69 98.31
35 INT3537 Positive_regulation of Car2 1 413 0.56 103.51 94.35
36 INT203 Positive_regulation of Pomc 2 257 0.70 90.56 92.84
37 INT82448 Gene_expression of S100a8 3 246 0.77 236.72 84.02
38 INT1498 Gene_expression of Gh 1 521 0.75 220.84 81.16
39 INT86521 Gene_expression of Lpar1 1 167 0.78 154.61 80.35
40 INT3214 Localization of Ins1 2 527 0.80 196.9 79.26
41 INT1497 Negative_regulation of Gh 3 415 0.59 192.95 74.71
42 INT117601 Positive_regulation of Trpa1 1 174 0.70 72.41 71.9
43 INT5374 Gene_expression of Esr1 31 412 0.77 263.89 67.34
44 INT4960 Positive_regulation of CSF2 1 285 0.70 256.73 65.73
45 INT1599 Positive_regulation of ADCY1 1 146 0.67 30.05 64.9
46 INT822 Gene_expression of ESR1 1 529 0.78 302.16 63.64
47 INT6894 Gene_expression of CNR1 2 168 0.78 74.07 62.84
48 INT17401 Gene_expression of IGF1 1 475 0.78 232.18 62.07
49 INT11318 Gene_expression of Gtf3a 3 274 0.52 183.82 60.89
50 INT39153 Positive_regulation of PTGS2 1 182 0.70 96.16 60.6
51 INT2761 Regulation of Gabrg1 3 119 0.61 18.8 60.52
52 INT14740 Gene_expression of TGFB1 1 272 0.78 168.48 60.18
53 INT129303 Positive_regulation of NAV1 1 54 0.70 36.92 57.45
54 INT21737 Binding of MC1R 1 129 0.48 45.45 56.54
55 INT33567 Gene_expression of CALM1 1 139 0.67 48.85 56.14
56 INT96937 Gene_expression of Mmp9 8 191 0.75 150.3 56.01
57 INT64159 Gene_expression of Prkca 1 90 0.78 34.65 55.97
58 INT52692 Gene_expression of Ptgs2 3 160 0.78 85.06 55.73
59 INT8528 Negative_regulation of Gene_expression of Fos 2 100 0.59 41.15 55.6
60 INT49993 Positive_regulation of Gene_expression of Il6 1 149 0.70 88.07 53.78
61 INT3213 Gene_expression of Ins1 47 511 0.76 357.59 53.32
62 INT1199 Positive_regulation of INS 1 579 0.70 399.64 50.43
63 INT9556 Negative_regulation of NAV1 1 47 0.59 28.49 49.33
64 INT17881 Gene_expression of LEP 1 278 0.78 221.61 48.31
65 INT62426 Gene_expression of Mc1r 13 127 0.78 42.99 48.01
66 INT106525 Phosphorylation of Akt1 1 436 0.82 183.81 47.82
67 INT6979 Positive_regulation of CA2 2 206 0.67 50.79 44.97
68 INT3361 Positive_regulation of Esr1 2 273 0.69 208.53 44.81
69 INT1564 Localization of OPRM1 1 41 0.80 8.03 44.67
70 INT115384 Positive_regulation of Mmp9 4 121 0.68 94.74 43.02
71 INT11939 Negative_regulation of Il6 1 138 0.59 87.46 41.24
72 INT69437 Positive_regulation of ROS1 1 328 0.58 222.83 40.56
73 INT97596 Localization of S100a8 2 94 0.78 90.69 40.41
74 INT92517 Gene_expression of Grin1 1 105 0.78 29.53 39.43
75 INT115 Negative_regulation of Maoa 2 65 0.59 16.27 38.66
76 INT107576 Gene_expression of Atf3 6 114 0.78 72.42 38.64
77 INT116321 Regulation of Nav1 1 38 0.62 26.62 37.97
78 INT14031 Gene_expression of Npy 5 107 0.78 36.48 35.4
79 INT8747 Positive_regulation of Ins1 18 221 0.69 154.28 35.15
80 INT11013 Negative_regulation of Phosphorylation of Creb1 2 55 0.59 18.74 34.66
81 INT103262 Localization of Nav1 1 53 0.81 19.23 34.44
82 INT14559 Gene_expression of Igf1 6 254 0.78 112 34.17
83 INT74563 Positive_regulation of Gene_expression of ROS1 1 258 0.61 168.18 34.08
84 INT49214 Gene_expression of Cd4 1 269 0.78 154.22 34.05
85 INT11325 Gene_expression of HLA-E 25 209 0.76 98.05 33.72
86 INT666 Gene_expression of Jun 1 124 0.78 54.61 33.67
87 INT5489 Localization of CA2 5 172 0.80 39.46 33.56
88 INT16714 Regulation of Creb1 2 64 0.62 22.23 33.56
89 INT33768 Positive_regulation of Cysltr1 3 87 0.46 54.66 33.52
90 INT62830 Gene_expression of VCAM1 3 149 0.78 125.23 32.4
91 INT96913 Positive_regulation of Mapk8 6 179 0.69 130.44 32.2
92 INT9796 Gene_expression of Cck 3 63 0.78 11.44 32.09
93 INT10797 Binding of CYP2D6 2 86 0.48 15.09 31.16
94 INT6277 Positive_regulation of Gene_expression of Pomc 1 76 0.70 21.45 31.09
95 INT34729 Positive_regulation of IFN1@ 1 233 0.67 128.04 30.38
96 INT52690 Positive_regulation of Ptgs2 1 65 0.68 39.51 30.02
97 INT169180 Binding of SNRNP70 22 204 0.47 119.1 29.3
98 INT28361 Gene_expression of TP53 2 443 0.78 384.86 28.8
99 INT37296 Binding of Esr1 13 117 0.43 62.51 27.33
100 INT5206 Gene_expression of AR 1 316 0.78 113.83 27.29
101 INT3217 Regulation of Ins1 8 154 0.62 87.11 27.29
102 INT20462 Binding of ESR1 1 210 0.44 102.7 26.34
103 INT62710 Gene_expression of HGF 3 160 0.78 88.27 26.14
104 INT11159 Gene_expression of EGFR 1 698 0.78 548.93 25.69
105 INT116226 Regulation of NAV1 1 20 0.51 14.32 25.61
106 INT101483 Gene_expression of Lep 3 159 0.78 104.77 25.12
107 INT256285 Gene_expression of Efnb1 2 32 0.70 36.25 24.73
108 INT86295 Gene_expression of Mmp2 1 114 0.76 73.68 24.25
109 INT10835 Regulation of IL8 2 79 0.49 53.04 24.14
110 INT67585 Gene_expression of UGT2B7 1 52 0.78 2.33 24.13
111 INT7827 Binding of Cck 1 32 0.48 4.66 23.73
112 INT129157 Positive_regulation of Atf3 2 48 0.69 35.42 22.87
113 INT19330 Binding of HLA-A 1 99 0.48 76.26 22.85
114 INT17962 Regulation of Car2 1 124 0.41 33.98 22.71
115 INT91891 Gene_expression of Kit 23 268 0.78 158.89 22.67
116 INT18322 Negative_regulation of Ins1 6 132 0.58 88.49 22.59
117 INT127435 Gene_expression of Per1 2 89 0.77 13.94 22.31
118 INT8483 Positive_regulation of Positive_regulation of TNF 3 73 0.67 60.35 22.03
119 INT8580 Gene_expression of ELANE 2 132 0.75 62.98 21.79
120 INT10536 Gene_expression of Trib3 1 67 0.66 27.08 21.58
121 INT121872 Gene_expression of Camk4 1 156 0.78 70.47 21.39
122 INT52693 Positive_regulation of Gene_expression of Ptgs2 2 57 0.70 25.51 21.18
123 INT24569 Negative_regulation of Pain1 2 26 0.41 21.82 21.08
124 INT11161 Gene_expression of HLA-DRB1 9 121 0.78 75.33 20.96
125 INT49774 Binding of DRD2 1 48 0.48 17.42 20.73
126 INT50814 Positive_regulation of Mmp2 1 72 0.68 51.37 20.42
127 INT111401 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 134 0.61 34.87 20.15
128 INT111401 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 134 0.61 34.87 20.15
129 INT8662 Positive_regulation of EDN1 1 144 0.70 125.34 19.59
130 INT23533 Gene_expression of CA2 4 110 0.75 30.81 19.4
131 INT12725 Positive_regulation of Racgap1 2 66 0.68 32.74 19.29
132 INT28951 Negative_regulation of IGF1 1 133 0.59 75.77 18.9
133 INT33327 Positive_regulation of Gene_expression of Gabrg1 1 39 0.69 9.68 18.82
134 INT61158 Negative_regulation of Creb1 1 33 0.59 11.54 18.06
135 INT20631 Positive_regulation of CHKB 3 166 0.69 109.86 17.92
136 INT150934 Gene_expression of GCH1 2 17 0.78 14.54 17.53
137 INT4067 Negative_regulation of Esr1 10 97 0.50 43.45 17.52
138 INT109316 Negative_regulation of Mapk8 4 72 0.59 50.59 17.24
139 INT95767 Negative_regulation of Mmp9 3 72 0.57 49.14 17.1
140 INT65856 Positive_regulation of TP53 1 138 0.67 112.65 16.71
141 INT93361 Gene_expression of Trp53 2 208 0.78 175.35 16.65
142 INT17313 Positive_regulation of HSPG2 1 57 0.67 55.78 16.65
143 INT65659 Positive_regulation of STAT3 1 132 0.70 69.56 15.95
144 INT85639 Positive_regulation of Tg(CAG-EGFP)D4Nagy 1 95 0.43 24.83 15.69
145 INT85639 Positive_regulation of Tg(CAG-EGFP)D4Nagy 1 95 0.43 24.83 15.69
146 INT178828 Regulation of Pain1 6 12 0.14 16.1 15.64
147 INT170754 Localization of IFN1@ 1 121 0.78 66.78 15.6
148 INT52591 Gene_expression of KCNMA1 2 78 0.76 13.95 15.55
149 INT152730 Positive_regulation of S100a8 1 48 0.68 47.67 15.4
150 INT113606 Positive_regulation of Gene_expression of Mmp9 2 46 0.64 44 15.07
151 INT3002 Binding of SUGT1 5 62 0.24 55.9 14.91
152 INT125384 Positive_regulation of Pain1 5 23 0.49 17.1 14.83
153 INT105387 Gene_expression of HIF1A 3 116 0.77 98.62 14.66
154 INT27266 Regulation of Gene_expression of Pomc 3 41 0.62 6.74 14.59
155 INT88544 Gene_expression of MMRN1 4 102 0.75 68.8 14.55
156 INT107575 Positive_regulation of Gene_expression of Atf3 3 25 0.69 27.37 14.55
157 INT90766 Gene_expression of PCS 1 93 0.77 40.48 14.51
158 INT26975 Gene_expression of Adipoq 12 113 0.75 106.71 14.46
159 INT109511 Gene_expression of Bax 1 133 0.78 113.22 14.36
160 INT16321 Gene_expression of Cd3e 1 111 0.72 49.9 14.21
161 INT15044 Localization of Nts 1 30 0.75 4.58 13.72
162 INT56651 Binding of HLA-DRB1 5 58 0.48 52.25 13.68
163 INT47708 Gene_expression of Nr4a1 1 30 0.78 5.12 13.59
164 INT109304 Positive_regulation of Phosphorylation of Akt1 2 113 0.69 40.92 13.49
165 INT11699 Binding of HLA-E 3 85 0.47 52.51 13.41
166 INT33358 Gene_expression of Cysltr1 2 46 0.62 24.18 13.36
167 INT2038 Localization of Esr1 4 104 0.79 40.12 13.27
168 INT26545 Gene_expression of Hras1 2 173 0.78 79.54 13.21
169 INT3962 Regulation of AGT 2 50 0.62 20.96 13.01
170 INT97448 Negative_regulation of Mc1r 5 20 0.58 7.37 12.91
171 INT123593 Gene_expression of Snca 1 58 0.78 35.76 12.87
172 INT28420 Gene_expression of Ptgds 1 59 0.78 31.72 12.67
173 INT21979 Negative_regulation of EDN1 1 52 0.58 24.65 12.55
174 INT137614 Gene_expression of Lgals3 1 70 0.77 66.13 12.53
175 INT122812 Gene_expression of SNRNP70 13 130 0.75 67 12.5
176 INT14510 Gene_expression of SOD1 1 208 0.76 88.56 12.4
177 INT113490 Gene_expression of SCN9A 1 22 0.77 5.45 12.27
178 INT178338 Gene_expression of Tbx15 1 50 0.65 38.65 12.19
179 INT110988 Gene_expression of Insr 22 58 0.42 42.12 12.18
180 INT184844 Gene_expression of Snap25 56 130 0.78 14.32 12.13
181 INT71030 Binding of Mc1r 3 39 0.48 10.27 12.02
182 INT4047 Binding of F13A1 1 105 0.43 66.54 11.81
183 INT102731 Regulation of ABCB1 2 29 0.62 5.36 11.67
184 INT1636 Gene_expression of Sct 1 58 0.77 16.14 11.57
185 INT23402 Binding of HLA-DOA 4 74 0.48 52.01 10.89
186 INT11479 Positive_regulation of KCNMA1 1 30 0.68 10.07 10.82
187 INT4605 Negative_regulation of Gene_expression of INS 1 220 0.58 139.66 10.75
188 INT1708 Gene_expression of OXTR 3 56 0.78 6.92 10.69
189 INT121796 Gene_expression of NeuN 1 92 0.78 23.18 10.53
190 INT150540 Binding of TLR2 1 50 0.45 35.86 10.43
191 INT139443 Positive_regulation of GCH1 1 9 0.69 8.2 10.14
192 INT32344 Localization of LTF 3 30 0.80 15.28 10.09
193 INT10184 Regulation of EDN1 1 44 0.62 23.78 10.06
194 INT113605 Negative_regulation of Gene_expression of Mmp9 7 25 0.41 22.92 9.98
195 INT101481 Positive_regulation of Lep 1 81 0.69 62.59 9.95
196 INT49660 Positive_regulation of EGR1 2 54 0.69 32.17 9.89
197 INT82769 Positive_regulation of Grm1 1 20 0.00 7.78 9.82
198 INT11729 Regulation of IGF1 1 71 0.61 44.58 9.71
199 INT10139 Positive_regulation of F13A1 2 64 0.56 44.75 9.69
200 INT62919 Regulation of Gnas 2 22 0.43 5.61 9.55
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