J:PLoS Pathogens

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT176477 Binding of CXCR3 and CXCL10 14 1 0.25 10.61 5.87
2 INT179502 Binding of Cd14 and Tlr4 29 3 0.39 13.77 5.73
3 INT264953 Binding of POMC and TLR4 1 1 0.03 0.89 1.96
4 INT264947 Binding of POMC and TLR2 1 1 0.03 0.89 1.95
5 INT201940 Binding of IL8 and CXCL10 2 4 0.28 2.46 1.86
6 INT264950 Binding of FPR1 and BOC 1 2 0.11 0.67 1.55
7 INT254205 Binding of Myd88 and Tlr4 12 1 0.19 3.17 1.54
8 INT238009 Binding of Cxcr3 and Cxcl9 3 1 0.40 4.01 1.37
9 INT283426 Binding of Lcn2 and Nt5e 1 18 0.08 5.8 1.24
10 INT197092 TNF Regulation of VEGFA 4 1 0.21 2.78 1.22
11 INT260810 Binding of CXCL10 and CCL2 1 4 0.10 1.37 1.12
12 INT178663 Binding of CXCR3 and TH1L 2 1 0.04 2.24 1.01
13 INT276964 Binding of Tlr1 and Tlr2 11 1 0.24 4.22 0.89
14 INT264944 Binding of POMC and BOC 1 1 0.07 0.44 0.89
15 INT288201 Mapk14 Positive_regulation of Cish 1 2 0.03 0.06 0.82
16 INT190868 Binding of Marcks and Ltp 1 1 0.01 0.87 0.81
17 INT190869 Binding of Prkca and Ltp 1 1 0.03 0.86 0.81
18 INT190867 Binding of Marcks and Prkca 1 1 0.17 0.8 0.77
19 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 1 0.06 0.29 0.74
20 INT295720 PTGER2 Regulation of MMP9 1 1 0.01 0.53 0.7
21 INT222811 Binding of Hand2 and TH1L 4 1 0.03 8.26 0.69
22 INT264943 Negative_regulation of Binding of FPR1 and BOC 1 1 0.13 0.22 0.64
23 INT295705 Binding of IK and TNF 1 1 0.00 0.27 0.64
24 INT288202 Negative_regulation of Cd14 Positive_regulation of Positive_regulation of Mapk14 1 2 0.09 1.08 0.64
25 INT264946 Binding of FPR1 and GOPC 1 1 0.08 0.21 0.64
26 INT264952 Binding of GOPC and BOC 1 1 0.05 0.22 0.64
27 INT295724 CXCL12 Positive_regulation of MMP9 1 1 0.02 0.32 0.6
28 INT295721 CSF2 Positive_regulation of MMP9 1 1 0.06 0.32 0.6
29 INT346412 Binding of Tesc and Sv2a 1 10 0.02 0.6 0.59
30 INT285911 Binding of TLR4 and Cd14 1 1 0.05 1.13 0.51
31 INT283434 Lcn2 Positive_regulation of Localization of IL8 1 6 0.07 1.33 0.51
32 INT295708 Binding of EGF and CCL2 1 1 0.01 0.79 0.49
33 INT278379 Binding of Pstpip1 and Mefv 3 2 0.03 2.02 0.48
34 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 1 0.31 1.77 0.48
35 INT264948 BOC Negative_regulation of FPR1 1 1 0.13 0.18 0.48
36 INT264949 BOC Negative_regulation of Localization of FPR1 1 1 0.13 0.18 0.48
37 INT264975 BOC Negative_regulation of Localization of Oprd1 1 1 0.01 0.17 0.48
38 INT190870 BDNF Positive_regulation of Phosphorylation of Mapk1 1 1 0.12 0.54 0.44
39 INT264945 GOPC Positive_regulation of Positive_regulation of FPR1 1 1 0.10 0.2 0.44
40 INT346416 Binding of Tesc and Svs1 1 1 0.00 0.07 0.42
41 INT295709 PTGER2 Regulation of VEGFA 1 2 0.01 1.61 0.41
42 INT278389 Binding of Casp1 and Il1 2 1 0.09 0.82 0.36
43 INT288208 Binding of Mapk14 and Positive_regulation of Akt1 1 1 0.01 0.42 0.35
44 INT268110 PRKCA Positive_regulation of Phosphorylation of SNAP25 1 1 0.32 0.11 0.35
45 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 1 0.15 2.14 0.34
46 INT288200 Tlr2 Positive_regulation of Pik3r1 1 1 0.05 0.24 0.33
47 INT295755 Fgf2 Regulation of MMP9 1 1 0.07 0.99 0.33
48 INT295717 VEGFA Regulation of MMP9 1 1 0.01 0.98 0.33
49 INT295722 PTGER2 Positive_regulation of RAC1 1 2 0.02 2.14 0.32
50 INT295725 PTGER2 Positive_regulation of RAC2 1 1 0.05 1.92 0.32
51 INT288198 Binding of Tlr4 and Mapk14 1 1 0.01 0.63 0.31
52 INT288203 Binding of Cd14 and Mapk14 1 1 0.08 0.63 0.31
53 INT288205 Binding of Cd14 and Myd88 1 1 0.10 0.57 0.28
54 INT329528 Seh1l Positive_regulation of Gene_expression of Csf2 1 1 0.07 0.37 0.28
55 INT329529 Tnfaip8 Positive_regulation of Gene_expression of Csf2 1 1 0.07 0.35 0.28
56 INT344165 Regulation of Binding of Cxcr3 and Cxcl9 1 1 0.30 0.47 0.25
57 INT278403 Hps5 Positive_regulation of Il1 1 4 0.04 1.48 0.24
58 INT352081 Binding of CD4 and ADAM11 1 2 0.09 0.33 0.24
59 INT329530 Malt1 Positive_regulation of Positive_regulation of Nfkb1 1 1 0.06 0.48 0.22
60 INT346409 Negative_regulation of Binding of mn and Tesc 1 1 0.00 0.29 0.22
61 INT222787 Binding of HLA-DQB3 and FCRL4 1 4 0.00 1.18 0.22
62 INT346408 Binding of mn and Tesc 1 1 0.00 0.29 0.22
63 INT278390 Hps5 Positive_regulation of Darc 1 1 0.01 0.49 0.22
64 INT278391 Hps5 Positive_regulation of Hrec 1 1 0.01 0.5 0.22
65 INT295713 PTGER2 Positive_regulation of Regulation of CCL5 1 1 0.01 0.82 0.21
66 INT283429 Nt5e Regulation of Gene_expression of Cxcr1 1 1 0.00 0.22 0.2
67 INT283431 Lcn2 Regulation of Gene_expression of Cxcr1 1 1 0.01 0.22 0.2
68 INT173430 Binding of FLT4 and VEGFA 10 3 0.25 9.38 0.19
69 INT175727 IL1B Regulation of VEGFA 2 1 0.04 0.7 0.19
70 INT197095 IL1B Regulation of Positive_regulation of TNF 1 1 0.01 0.64 0.19
71 INT197093 TNF Regulation of Positive_regulation of IL1B 1 1 0.01 0.64 0.19
72 INT278407 Hps5 Positive_regulation of Gene_expression of Darc 1 1 0.01 0.22 0.19
73 INT197097 IL1B Regulation of FLT4 1 1 0.03 0.66 0.19
74 INT197098 TNF Regulation of FLT4 1 1 0.14 0.66 0.19
75 INT202508 Gpbar1 Positive_regulation of Positive_regulation of Nfasc 1 1 0.00 0.57 0.19
76 INT59166 Binding of fc and IgG 2 2 0.00 1.23 0.17
77 INT284558 Tlr4 Positive_regulation of Mat1a 1 2 0.14 0.24 0.17
78 INT222785 Binding of MR1 and ERVW-1 1 2 0.01 1.02 0.17
79 INT222877 Chrm2 Negative_regulation of EPHB2 1 1 0.05 0.66 0.17
80 INT278398 Hps5 Positive_regulation of Nlrp3 1 3 0.26 1.38 0.16
81 INT346414 Thy1 Positive_regulation of Binding of Tesc 1 1 0.00 0.16 0.15
82 INT278373 Myd88 Regulation of Phosphorylation of Syk 1 1 0.15 0.35 0.15
83 INT233386 Binding of Il12a and Il12b 1 1 0.01 0.48 0.15
84 INT278394 Myd88 Regulation of Phosphorylation of Hps5 1 1 0.11 0.35 0.15
85 INT283428 Negative_regulation of Binding of Lcn2 and Nt5e 1 3 0.06 1.09 0.15
86 INT222874 NDUFA6 Regulation of Chuk 1 4 0.01 1.57 0.15
87 INT346411 Binding of Caprin1 and Mtus1 1 1 0.00 0.17 0.14
88 INT346410 Binding of Caprin1 and Tesc 1 1 0.00 0.17 0.14
89 INT222783 Binding of MR1 and PTPRC 1 1 0.00 0.46 0.14
90 INT228111 Il10 Negative_regulation of Gene_expression of Ik 1 1 0.01 0.44 0.13
91 INT228119 Il10 Negative_regulation of H2 1 1 0.07 0.38 0.13
92 INT222876 Binding of NDUFA6 and Chuk 1 16 0.02 2.02 0.13
93 INT228110 Chrm2 Positive_regulation of Localization of Il10 1 4 0.33 0.66 0.13
94 INT352073 Positive_regulation of Binding of ADAM11 and CCL19 1 1 0.22 1.27 0.13
95 INT228113 H2 Negative_regulation of Gene_expression of Ik 1 1 0.00 0.33 0.13
96 INT222875 Binding of NDUFA6 and Positive_regulation of Chuk 1 1 0.01 0.74 0.13
97 INT222867 Binding of Il1 and Rpl13 1 1 0.00 0.39 0.13
98 INT222872 Binding of TNF and Rpl13 1 1 0.00 0.39 0.13
99 INT352080 Binding of ADAM11 and CCL19 1 1 0.16 1.27 0.13
100 INT287878 Binding of CREB1 and CREBBP 2 1 0.01 0.16 0.12
101 INT222777 IL4 Positive_regulation of Positive_regulation of MR1 1 1 0.03 0.45 0.12
102 INT222774 IL4 Positive_regulation of MRC1 1 1 0.01 0.45 0.12
103 INT222786 IL4 Positive_regulation of Positive_regulation of MRC1 1 1 0.01 0.45 0.12
104 INT222748 IL4 Positive_regulation of IL4 Positive_regulation of MR1 1 1 0.01 0.45 0.12
105 INT287035 Gopc Positive_regulation of Prtn3 1 1 0.02 0.48 0.12
106 INT222780 IL4 Positive_regulation of MR1 1 1 0.02 0.45 0.12
107 INT278397 Hps5 Positive_regulation of Tlr9 1 2 0.15 0.21 0.11
108 INT233384 Il10 Negative_regulation of Il12a 1 1 0.01 0.54 0.11
109 INT352084 AGRP Negative_regulation of Negative_regulation of ADAM11 1 1 0.06 0.98 0.11
110 INT284552 Binding of Cd8a and Mthfd1 2 1 0.03 1.32 0.1
111 INT265423 Ccl21a Positive_regulation of Gene_expression of CXCL10 1 2 0.30 0.88 0.1
112 INT265388 CCL21 Positive_regulation of Gene_expression of CXCL9 1 2 0.13 0.88 0.1
113 INT265422 Ccl21a Positive_regulation of Gene_expression of CXCL9 1 2 0.24 0.88 0.1
114 INT265389 CCL21 Positive_regulation of Gene_expression of CXCL10 1 2 0.16 0.88 0.1
115 INT201348 Binding of Il4 and Ik 1 1 0.01 0.67 0.09
116 INT341054 Binding of PAEP and RAB14 1 1 0.00 0.28 0.09
117 INT278378 Hps5 Positive_regulation of Gene_expression of S100a8 1 1 0.00 0.42 0.09
118 INT278371 Binding of Il1 and Hps5 1 1 0.02 0.44 0.09
119 INT283427 Lcn2 Positive_regulation of Nt5e 1 1 0.08 0.21 0.09
120 INT278368 Regulation of Binding of Il1 and Hps5 1 1 0.02 0.44 0.09
121 INT230065 Binding of TOR1A and HLA-DOA 1 2 0.00 1.65 0.09
122 INT201349 Binding of Hand2 and Il4 1 1 0.17 0.67 0.09
123 INT185279 Binding of CCND1 and CDK4 4 1 0.13 2.05 0.08
124 INT222873 NDUFA6 Negative_regulation of Phosphorylation of Chuk 1 2 0.01 0.24 0.08
125 INT222784 IL13 Positive_regulation of Gene_expression of MR1 1 1 0.01 0.53 0.08
126 INT222788 IL4 Positive_regulation of Gene_expression of MR1 1 2 0.02 0.96 0.08
127 INT222781 Positive_regulation of Binding of HLA-DQB3 and FCRL4 1 1 0.00 0.32 0.08
128 INT288210 Regulation of Tlr2 Positive_regulation of Akt1 1 1 0.03 0.09 0.08
129 INT202505 Binding of Cd40lg and Positive_regulation of Positive_regulation of Nfasc 1 1 0.09 0.45 0.08
130 INT228116 Tlr4 Positive_regulation of Localization of Il10 1 1 0.09 0.06 0.08
131 INT222812 NDUFA6 Negative_regulation of Gene_expression of IFNA1 1 1 0.00 0.22 0.08
132 INT288206 Tlr2 Positive_regulation of Akt1 1 1 0.04 0.09 0.08
133 INT278376 Negative_regulation of Casp1 Negative_regulation of Hps5 1 1 0.05 0.05 0.08
134 INT222869 Rpl13 Regulation of Il10 1 1 0.00 0.22 0.07
135 INT222775 Binding of HLA-DQB3 and MR1 1 1 0.00 0.35 0.07
136 INT288204 Akt1 Regulation of Mapk14 1 1 0.01 0.09 0.07
137 INT283425 Lcn2 Positive_regulation of Gene_expression of Nt5e 1 1 0.07 0.13 0.07
138 INT222779 Negative_regulation of Binding of HLA-DQB3 and FCRL4 1 1 0.00 0.32 0.07
139 INT283433 Nt5e Positive_regulation of Localization of IL8 1 1 0.01 0.21 0.07
140 INT346415 Binding of Mns1 and Sv2a 1 1 0.03 0.14 0.07
141 INT202506 Psmb8 Positive_regulation of Nfasc 1 1 0.01 0.59 0.06
142 INT344225 Binding of fc and Krt1 1 6 0.00 0.39 0.06
143 INT269501 Nos1 Regulation of Lta 1 1 0.28 0.26 0.05
144 INT284562 Gopc Positive_regulation of Mat1a 1 1 0.12 0.22 0.05
145 INT284557 Gopc Positive_regulation of Cd86 1 1 0.21 0.23 0.05
146 INT284565 Gopc Positive_regulation of Mthfd1 1 1 0.11 0.22 0.05
147 INT284559 Gopc Positive_regulation of Cd40 1 1 0.19 0.23 0.05
148 INT295715 PTGER2 Regulation of Localization of FGF2 1 1 0.02 0.6 0.05
149 INT295719 VEGFA Regulation of Localization of PTGER2 1 1 0.02 0.6 0.05
150 INT284564 Binding of Itgax and Mthfd1 1 1 0.08 0.09 0.05
151 INT295723 VEGFA Regulation of Localization of FGF2 1 1 0.07 0.6 0.05
152 INT222878 NDUFA6 Negative_regulation of Chuk 1 6 0.01 2.06 0.05
153 INT268111 Binding of MARCKS and SNAP25 1 1 0.09 0 0.05
154 INT265386 DCPS Positive_regulation of Localization of CXCL10 1 1 0.01 0.07 0.05
155 INT284561 Positive_regulation of Gopc Positive_regulation of Mat1a 1 1 0.12 0.23 0.05
156 INT352087 Binding of ADAM11 and TLR4 1 1 0.05 1.09 0.04
157 INT265387 CXCL10 Positive_regulation of Positive_regulation of TH1L 1 1 0.06 0.24 0.04
158 INT352075 AGRP Negative_regulation of Positive_regulation of ADAM11 1 2 0.06 1.64 0.04
159 INT322671 Binding of Gfm1 and Pbrm1 1 1 0.00 0.96 0.04
160 INT346418 Sv2a Positive_regulation of Binding of Tesc 1 1 0.02 0.1 0.04
161 INT352076 Binding of TLR4 and Positive_regulation of ADAM11 1 1 0.06 1.09 0.04
162 INT295718 Binding of PTGER2 and Positive_regulation of Positive_regulation of SP1 1 1 0.02 0.58 0.04
163 INT341055 Binding of HRC and RAB14 1 1 0.00 0 0.04
164 INT314967 Binding of Cd4 and Mthfd1 1 1 0.09 0.11 0.04
165 INT333559 TBK1 Regulation of Phosphorylation of IRF3 1 1 0.17 0.35 0.04
166 INT172902 Binding of Bax and Bcl2 5 2 0.30 3.19 0.03
167 INT310041 Gtf3a Positive_regulation of Met 1 1 0.00 0.15 0.03
168 INT346407 Negative_regulation of Binding of Tesc and Sv2a 1 1 0.02 0 0.03
169 INT333633 Thse Positive_regulation of Transcription of IRF3 1 1 0.00 1.13 0.03
170 INT288199 Binding of Ptprc and Trav6-3 1 1 0.00 0.05 0.03
171 INT333636 Rai1 Negative_regulation of Gene_expression of IFNA1 1 1 0.05 1.16 0.03
172 INT322667 Binding of Vdac1 and Pbrm1 1 1 0.15 0.79 0.03
173 INT269502 Lta Negative_regulation of Map2k1 1 1 0.17 0.48 0.03
174 INT198143 Binding of AR and ANTXR2 1 1 0.01 0.19 0.03
175 INT333635 Positive_regulation of Tlr4 Positive_regulation of Transcription of CREB1 1 1 0.08 0 0.03
176 INT268217 Gopc Positive_regulation of Gene_expression of Ang2 1 1 0.03 2.28 0.03
177 INT333632 Tlr4 Positive_regulation of Transcription of FYN 1 1 0.07 0 0.03
178 INT333640 Tlr4 Positive_regulation of Transcription of CREB1 1 1 0.08 0 0.03
179 INT333568 FYN Regulation of Transcription of JUN 1 1 0.01 0 0.03
180 INT260811 Binding of ITGA4 and ITGAL 1 1 0.02 0 0.03
181 INT333631 Thse Negative_regulation of Gene_expression of IFNA1 1 1 0.00 1.15 0.03
182 INT230066 IL15 Positive_regulation of Gene_expression of KLRD1 1 1 0.01 0.37 0.03
183 INT322672 Binding of SLC25A6 and Pbrm1 1 2 0.04 1.87 0.03
184 INT269504 Lta Negative_regulation of Map2k1 Negative_regulation of Nos1 1 1 0.17 0.49 0.03
185 INT310040 Hgf Positive_regulation of Met 1 1 0.06 0.15 0.03
186 INT352074 ADAM11 Positive_regulation of Gene_expression of CCL19 1 1 0.17 0.74 0.03
187 INT278408 Hps5 Positive_regulation of Localization of Ctsb 1 2 0.05 0.11 0.03
188 INT333634 Positive_regulation of Tlr4 Positive_regulation of Transcription of FYN 1 1 0.07 0 0.03
189 INT333564 CREB1 Regulation of Transcription of JUN 1 1 0.02 0 0.03
190 INT222776 Binding of MRC1 and ERVW-1 1 1 0.00 0.56 0.03
191 INT282995 Binding of Bcl2 and Becn1 21 18 0.03 9.8 0
192 INT219423 Binding of AHR and ARNT 4 2 0.24 0.46 0
193 INT283013 Binding of Bak1 and Bcl2 4 4 0.06 1.03 0
194 INT254232 Binding of Tlr4 and TRAM1 2 1 0.07 1.11 0
195 INT260518 Binding of Prnp and Gopc 2 2 0.13 1.06 0
196 INT278404 Syk Positive_regulation of Mapk1 1 1 0.13 0 0
197 INT268187 Rab4a Regulation of Rab22a 1 1 0.15 0.12 0
198 INT283001 Binding of Becn1 and Om 1 1 0.00 0.1 0
199 INT268647 ATP2B3 Positive_regulation of Prnp 1 1 0.01 0.57 0
200 INT295702 PTGER2 Positive_regulation of Racgap1 1 1 0.05 0.22 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 22 3152 0.78 2515.62 929.82
2 INT7114 Positive_regulation of Ltp 3 1192 0.62 290.76 755.77
3 INT443 Localization of POMC 12 1020 0.81 284.52 443.17
4 INT9238 Gene_expression of IL6 11 1575 0.78 1135.66 424.22
5 INT467 Gene_expression of POMC 4 1048 0.78 332.8 394.16
6 INT5235 Negative_regulation of TNF 3 924 0.59 772.91 331.98
7 INT5059 Positive_regulation of TNF 16 1050 0.70 896.51 322.81
8 INT5979 Gene_expression of Oprd1 2 428 0.78 75.64 320.32
9 INT49750 Negative_regulation of CPOX 6 735 0.58 360.06 274.19
10 INT6852 Localization of TNF 11 883 0.81 705.95 270.84
11 INT10832 Gene_expression of IL8 9 1050 0.78 698.72 270
12 INT9659 Gene_expression of Il6 16 991 0.78 715.11 265.57
13 INT5972 Gene_expression of IL1B 3 948 0.78 510.91 263.97
14 INT68684 Gene_expression of VEGFA 39 2371 0.78 1742.52 259.2
15 INT738 Regulation of POMC 1 459 0.62 111.19 243.74
16 INT1665 Positive_regulation of Pag1 1 270 0.68 186.63 229.87
17 INT95787 Positive_regulation of Mapk1 3 568 0.70 226.51 220.94
18 INT6665 Gene_expression of FOS 2 520 0.77 165.31 217.66
19 INT6481 Binding of TNF 2 624 0.48 510.2 214.82
20 INT6482 Positive_regulation of Gene_expression of TNF 6 659 0.70 569.88 210
21 INT50670 Gene_expression of CPOX 2 763 0.76 442.13 195.02
22 INT10194 Positive_regulation of IL6 1 702 0.70 600.62 183.38
23 INT1429 Gene_expression of PDYN 1 308 0.78 61.33 175.65
24 INT19472 Gene_expression of Il1 20 554 0.76 419.75 175.35
25 INT4937 Negative_regulation of Oprd1 1 224 0.59 44.51 171.11
26 INT867 Gene_expression of IFNA1 24 930 0.78 594.85 168.03
27 INT739 Negative_regulation of POMC 3 358 0.59 102.28 166.77
28 INT55879 Gene_expression of CCL2 4 421 0.78 240.74 166.02
29 INT66280 Gene_expression of Nos2 2 534 0.78 330.78 157.07
30 INT120811 Gene_expression of Gopc 29 1174 0.59 428.49 150.55
31 INT7628 Gene_expression of Ltp 1 273 0.77 70.21 147.87
32 INT60694 Gene_expression of Il10 58 567 0.78 369.48 143.69
33 INT9660 Regulation of TNF 1 363 0.62 312.94 139.99
34 INT64161 Positive_regulation of Prkca 9 213 0.70 85.06 129.91
35 INT65600 Positive_regulation of Casp3 2 376 0.70 198.44 128.03
36 INT6128 Positive_regulation of Localization of POMC 2 256 0.70 68.77 121.64
37 INT7533 Gene_expression of Tlr4 12 720 0.78 343.22 121.57
38 INT8243 Positive_regulation of Il6 6 451 0.70 358.24 119.28
39 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 22 1138 0.72 311.58 119.18
40 INT9235 Negative_regulation of Gene_expression of TNF 2 346 0.59 252.98 118.61
41 INT12339 Localization of IL8 16 437 0.81 251.87 117.39
42 INT48593 Positive_regulation of NOS1 3 420 0.68 226.15 114.71
43 INT20374 Gene_expression of Il4 15 515 0.76 306.15 114.12
44 INT27096 Positive_regulation of Nfkb1 3 325 0.70 195.11 109.06
45 INT60526 Gene_expression of IL10 4 449 0.78 292.71 107.84
46 INT12082 Localization of IL6 4 365 0.81 241.78 105.78
47 INT49171 Gene_expression of Nos1 2 241 0.78 140.7 104.76
48 INT12569 Localization of Oprd1 32 94 0.81 23.81 104.56
49 INT69440 Gene_expression of ROS1 12 752 0.78 477.64 103.83
50 INT90091 Gene_expression of GOPC 9 967 0.67 366.22 103.6
51 INT10838 Positive_regulation of IL8 5 381 0.70 295.51 101.62
52 INT11381 Positive_regulation of IL1B 3 330 0.70 209.31 100.9
53 INT1760 Gene_expression of PTGER2 11 524 0.57 226.94 96.4
54 INT11587 Gene_expression of CSF2 4 645 0.78 544.38 93.89
55 INT77435 Positive_regulation of Nos2 6 343 0.70 208.49 91.43
56 INT96917 Positive_regulation of Mapk14 7 261 0.70 173.29 88.79
57 INT64158 Negative_regulation of Prkca 3 121 0.59 29.8 88.66
58 INT15898 Positive_regulation of Prkaca 3 199 0.70 50.89 87.54
59 INT82448 Gene_expression of S100a8 2 246 0.77 236.72 84.02
60 INT92434 Phosphorylation of Mapk1 2 287 0.82 91.65 83.46
61 INT68682 Positive_regulation of VEGFA 9 640 0.70 454.14 81.65
62 INT56291 Gene_expression of Ros1 6 503 0.63 274.12 81.5
63 INT2893 Localization of Oxt 1 219 0.80 28.96 79.43
64 INT13036 Positive_regulation of Positive_regulation of Ltp 1 105 0.51 23.71 77.66
65 INT60691 Gene_expression of Il12a 21 331 0.78 208.03 75.96
66 INT1724 Negative_regulation of ACE 1 437 0.59 315.64 74.48
67 INT9236 Regulation of Gene_expression of TNF 1 204 0.62 162.66 72.99
68 INT56298 Gene_expression of IL4 4 306 0.78 182.18 72.92
69 INT11380 Negative_regulation of IL1B 3 215 0.59 125.62 72.35
70 INT12720 Positive_regulation of Il1 9 246 0.70 195.97 72.05
71 INT57380 Phosphorylation of Creb1 2 213 0.82 66.8 71.26
72 INT10837 Positive_regulation of Gene_expression of IL8 3 294 0.70 190.08 70.34
73 INT79494 Positive_regulation of Gene_expression of VEGFA 11 577 0.70 442.94 69.73
74 INT170332 Gene_expression of IFN1@ 6 477 0.75 275.21 69.65
75 INT53964 Negative_regulation of Prkaca 1 131 0.58 38.76 69.52
76 INT4960 Positive_regulation of CSF2 1 285 0.70 256.73 65.73
77 INT1425 Gene_expression of Rbm39 1 143 0.58 51.32 65.44
78 INT11807 Gene_expression of Il2 2 266 0.78 112 64.97
79 INT11937 Localization of Il6 3 228 0.81 139.83 64.39
80 INT9657 Positive_regulation of Gene_expression of Il6 3 237 0.70 180.45 63.6
81 INT1951 Positive_regulation of Tlr4 8 345 0.70 176.99 62.42
82 INT67981 Positive_regulation of CCL2 1 165 0.70 136.84 61.85
83 INT11318 Gene_expression of Gtf3a 1 274 0.52 183.82 60.89
84 INT5058 Positive_regulation of IFNA1 13 356 0.70 245.75 60.52
85 INT103924 Positive_regulation of Akt1 5 359 0.69 158.94 60.34
86 INT546 Binding of ALB 1 311 0.48 85.98 60.14
87 INT50672 Positive_regulation of CPOX 2 205 0.44 125.93 60.06
88 INT1536 Negative_regulation of NA 10 244 0.55 52.67 59.79
89 INT102020 Gene_expression of Creb1 6 190 0.78 57.31 59.77
90 INT1759 Gene_expression of TIMP1 4 267 0.77 133.87 59.29
91 INT49170 Negative_regulation of Nos1 3 116 0.59 60.66 58.87
92 INT169926 Positive_regulation of Gopc 13 416 0.46 157.8 58.67
93 INT82055 Positive_regulation of Creb1 4 176 0.70 60.2 58.39
94 INT73048 Gene_expression of MMP9 7 268 0.77 159.75 57.81
95 INT46637 Gene_expression of CXCL10 14 172 0.78 121.94 57.74
96 INT5356 Positive_regulation of FOS 2 153 0.69 54.21 56.74
97 INT4509 Gene_expression of IGG 6 426 0.76 293.69 56.64
98 INT5453 Regulation of Localization of POMC 1 114 0.62 20.56 56.34
99 INT64159 Gene_expression of Prkca 1 90 0.78 34.65 55.97
100 INT78899 Gene_expression of CCL5 5 155 0.77 84.02 55.09
101 INT63975 Positive_regulation of Il10 12 175 0.68 134.13 54.69
102 INT117223 Gene_expression of TLR4 3 348 0.78 206.18 54.42
103 INT96914 Phosphorylation of Mapk14 5 168 0.82 108.46 53.32
104 INT22112 Positive_regulation of Localization of TNF 3 164 0.70 115.66 52.18
105 INT72182 Gene_expression of Mcpt1 1 167 0.75 123.7 52.15
106 INT249 Localization of GHRH 1 215 0.80 78.02 51.87
107 INT52264 Gene_expression of IK 7 180 0.77 90.87 51.87
108 INT66040 Positive_regulation of Bdnf 1 114 0.69 67.67 51.81
109 INT64110 Positive_regulation of Gene_expression of Nos1 1 68 0.70 58.11 51.64
110 INT20382 Gene_expression of Hand2 3 211 0.66 142.26 51.05
111 INT19775 Localization of Il1 1 183 0.78 145.5 50.91
112 INT1232 Positive_regulation of Pdpk1 1 78 0.42 24.33 50.17
113 INT9210 Regulation of IL6 1 166 0.62 125.61 49.95
114 INT55671 Gene_expression of Ik 8 151 0.27 80.1 48.49
115 INT1197 Negative_regulation of Localization of POMC 2 109 0.59 28.29 48.02
116 INT106525 Phosphorylation of Akt1 5 436 0.82 183.81 47.82
117 INT26500 Gene_expression of MMP2 7 201 0.78 110.57 46.9
118 INT48718 Positive_regulation of PRKCA 1 109 0.69 36.16 46.49
119 INT110023 Negative_regulation of Mapk14 12 127 0.59 84.27 45.42
120 INT145266 Gene_expression of IL17A 1 154 0.75 109.83 45.33
121 INT81498 Positive_regulation of Gene_expression of CCL2 1 107 0.70 53.89 45.22
122 INT16364 Gene_expression of HLA-DRA 1 234 0.78 118.81 45.01
123 INT6979 Positive_regulation of CA2 2 206 0.67 50.79 44.97
124 INT18522 Positive_regulation of Gene_expression of IFNA1 8 248 0.67 160.85 44.87
125 INT3361 Positive_regulation of Esr1 2 273 0.69 208.53 44.81
126 INT80124 Negative_regulation of VEGFA 7 450 0.58 311.19 44.53
127 INT2774 Binding of Crp 3 241 0.48 195.89 44.39
128 INT4216 Gene_expression of CD40LG 1 328 0.78 256.02 44.23
129 INT25610 Positive_regulation of Gene_expression of Il1 5 136 0.67 104.43 43.86
130 INT83953 Gene_expression of Cxcl2 2 140 0.75 113.07 43.65
131 INT100939 Gene_expression of Il13 2 176 0.73 125.1 43.38
132 INT66383 Phosphorylation of Prkaca 1 143 0.80 30.85 43.38
133 INT25383 Gene_expression of Csf2 7 222 0.76 152.93 43.32
134 INT60695 Positive_regulation of Gene_expression of Il10 10 154 0.70 120.28 43.07
135 INT52531 Gene_expression of Nfkb1 1 153 0.75 82.84 42.9
136 INT157666 Positive_regulation of GOPC 4 335 0.60 120.19 42.75
137 INT85943 Negative_regulation of Nos2 1 161 0.59 108.56 42.65
138 INT170054 Negative_regulation of Gopc 10 280 0.38 117.89 42.4
139 INT13354 Transcription of TNF 2 108 0.72 85.81 42.32
140 INT61619 Gene_expression of IL12A 3 194 0.77 146.07 41.97
141 INT13556 Gene_expression of CD4 1 367 0.78 230.82 41.74
142 INT57442 Phosphorylation of Prkca 19 98 0.70 31.58 41.04
143 INT69437 Positive_regulation of ROS1 21 328 0.58 222.83 40.56
144 INT97596 Localization of S100a8 1 94 0.78 90.69 40.41
145 INT92437 Positive_regulation of Phosphorylation of Mapk1 1 113 0.70 32.19 40.29
146 INT3987 Positive_regulation of IGHE 1 316 0.70 283.2 40.16
147 INT88322 Gene_expression of CCR5 4 111 0.78 77.36 39.84
148 INT89661 Gene_expression of Hrec 3 102 0.21 69.91 39.57
149 INT102611 Negative_regulation of Positive_regulation of Mapk1 1 74 0.58 35.57 39.37
150 INT77434 Positive_regulation of Gene_expression of Nos2 1 151 0.69 96.76 38.94
151 INT173693 Localization of Gopc 4 249 0.65 70.49 38.81
152 INT77307 Gene_expression of Bcl2 72 399 0.77 319.77 38
153 INT48222 Positive_regulation of Localization of IL8 3 123 0.59 78.04 37.2
154 INT168410 Gene_expression of Cxcr3 2 81 0.75 84.03 37.01
155 INT63349 Gene_expression of PECAM1 2 199 0.75 166.03 36.76
156 INT133028 Gene_expression of TLR2 2 209 0.73 131.92 36.17
157 INT101992 Localization of VEGFA 26 413 0.81 258.23 36.15
158 INT72651 Gene_expression of TH1L 6 114 0.75 80.15 35.15
159 INT104392 Gene_expression of Cxcl10 7 113 0.75 106.86 34.12
160 INT74563 Positive_regulation of Gene_expression of ROS1 5 258 0.61 168.18 34.08
161 INT49214 Gene_expression of Cd4 4 269 0.78 154.22 34.05
162 INT81289 Positive_regulation of Gene_expression of Tlr4 3 192 0.69 104.5 33.89
163 INT11325 Gene_expression of HLA-E 4 209 0.76 98.05 33.72
164 INT666 Gene_expression of Jun 3 124 0.78 54.61 33.67
165 INT5489 Localization of CA2 4 172 0.80 39.46 33.56
166 INT84825 Gene_expression of CD36 1 121 0.78 43.73 33.23
167 INT52350 Gene_expression of CD14 8 184 0.75 71.37 33.13
168 INT9694 Positive_regulation of Csf2 3 102 0.68 70.09 33.07
169 INT64171 Regulation of CPOX 2 109 0.36 55.36 32.96
170 INT10248 Gene_expression of KRT20 2 436 0.78 231.96 32.88
171 INT6302 Binding of IFNA1 4 196 0.48 133.85 32.73
172 INT65698 Localization of CCL2 9 118 0.81 77.54 32.69
173 INT99610 Localization of MMP9 11 126 0.79 48.46 32.67
174 INT73498 Gene_expression of IL13 3 117 0.44 83.85 32.26
175 INT96913 Positive_regulation of Mapk8 5 179 0.69 130.44 32.2
176 INT114881 Gene_expression of Akt1 3 227 0.78 102.49 31.81
177 INT88318 Gene_expression of CXCR4 3 208 0.77 189.67 31.72
178 INT48693 Regulation of VEGFA 5 268 0.62 191.88 31.52
179 INT13186 Positive_regulation of Il4 4 113 0.68 71.22 31.4
180 INT17886 Negative_regulation of Il1 1 95 0.57 70.91 31.25
181 INT56809 Binding of Tlr4 11 184 0.48 106.02 31.18
182 INT117112 Negative_regulation of Mapk1 2 87 0.56 40.34 31.18
183 INT99688 Negative_regulation of Gene_expression of VEGFA 4 274 0.58 201.8 31.1
184 INT64164 Regulation of Prkca 1 34 0.62 10.44 30.99
185 INT129207 Gene_expression of Cxcl1 5 114 0.75 68.54 30.82
186 INT54302 Positive_regulation of Gene_expression of Il4 4 126 0.68 86.18 30.75
187 INT34729 Positive_regulation of IFN1@ 6 233 0.67 128.04 30.38
188 INT110020 Gene_expression of Mapk14 3 142 0.77 72.33 30.08
189 INT90792 Localization of Il10 29 144 0.80 87.88 30.03
190 INT52690 Positive_regulation of Ptgs2 1 65 0.68 39.51 30.02
191 INT10915 Gene_expression of ITGAM 1 164 0.78 92.42 29.78
192 INT6660 Positive_regulation of Jun 4 148 0.69 67.58 29.73
193 INT50230 Positive_regulation of Localization of IL6 1 105 0.70 69.21 29.52
194 INT11554 Negative_regulation of CSF2 1 129 0.59 108.55 29.44
195 INT15174 Gene_expression of Itgam 12 238 0.73 104.92 29.26
196 INT47712 Positive_regulation of App 1 135 0.69 101.38 28.94
197 INT28361 Gene_expression of TP53 1 443 0.78 384.86 28.8
198 INT15610 Localization of GOPC 8 223 0.65 68.26 28.7
199 INT65598 Negative_regulation of Positive_regulation of Casp3 1 45 0.59 18.36 28.59
200 INT52712 Negative_regulation of PRKCA 2 64 0.57 23.11 28.43
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