J:PPAR Research

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT101942 Binding of CD40 and CD40LG 16 1 0.23 15.24 4.01
2 INT121651 Binding of CXCL12 and CXCR4 13 5 0.48 17.61 3.52
3 INT290667 Il6 Positive_regulation of Stat3 3 2 0.69 2.42 1.15
4 INT202620 Binding of Ppara and Rxra 15 10 0.09 2.63 1.11
5 INT237379 Binding of Ebi3 and Il27 2 1 0.05 1.71 0.82
6 INT100783 Binding of CYP2B6 and CYP3A4 2 1 0.17 2 0.77
7 INT184125 Il12a Positive_regulation of Stat4 2 1 0.11 1.04 0.7
8 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 1 0.18 1.18 0.69
9 INT335054 LPL Positive_regulation of Localization of VLDLR 1 4 0.04 1.48 0.67
10 INT231533 IL4 Positive_regulation of LRP5 1 1 0.00 0.87 0.67
11 INT308668 Akt1 Positive_regulation of Nos3 3 2 0.05 4.61 0.65
12 INT231534 Binding of JAK1 and SOAT1 1 2 0.01 0.6 0.64
13 INT237907 Tlr4 Positive_regulation of Gene_expression of Tlr2 7 1 0.40 5.85 0.6
14 INT178437 Mapk8 Positive_regulation of Jun 3 1 0.40 2.69 0.58
15 INT115146 MAPK1 Positive_regulation of EGR1 3 1 0.13 2.43 0.57
16 INT144035 IL6 Positive_regulation of STAT3 4 1 0.31 2.58 0.56
17 INT211993 Binding of Ppara and Rorb 1 1 0.00 1.13 0.54
18 INT270044 Il10 Positive_regulation of Positive_regulation of Hmox1 1 2 0.20 1.59 0.53
19 INT304576 Binding of Arntl and Clock 6 4 0.37 0.43 0.5
20 INT285688 Cpox Positive_regulation of PPARA 1 1 0.02 1 0.5
21 INT240537 Binding of Il12a and Ebi3 1 1 0.08 1.23 0.49
22 INT240441 Ltb4r1 Positive_regulation of PPARA 1 1 0.03 1.01 0.47
23 INT240442 Binding of PPARA and Ltb4r1 1 1 0.02 0.94 0.46
24 INT290671 Binding of Socs3 and Stat3 2 1 0.23 1.59 0.45
25 INT270043 Binding of Ldlr and Hdl1 1 2 0.01 2.3 0.43
26 INT238382 Il13 Positive_regulation of Gene_expression of Ppara 1 1 0.18 0.79 0.4
27 INT236110 Binding of Ppara and Olfm4 1 1 0.00 1.22 0.4
28 INT238384 Tlr4 Positive_regulation of Prkca 1 1 0.06 0.81 0.4
29 INT191493 Binding of AGTR1 and NLRP3 2 1 0.03 2.35 0.39
30 INT236111 Binding of Pdpk1 and Ppara 1 1 0.26 1.21 0.39
31 INT237369 SOAT1 Negative_regulation of Phosphorylation of JAK1 1 1 0.00 0 0.38
32 INT235432 Ppara Negative_regulation of Gene_expression of Cpox 1 1 0.01 1 0.37
33 INT221814 Mastl Positive_regulation of Ppara 1 1 0.04 0.68 0.37
34 INT231535 Binding of JAK2 and SOAT1 1 1 0.01 0.3 0.35
35 INT297352 KLF2 Regulation of PPARA 1 1 0.12 1.31 0.35
36 INT301665 CYP2C9 Regulation of Binding of Ppara 1 1 0.26 1.79 0.34
37 INT297351 EWSR1 Positive_regulation of PPARA 1 1 0.41 1.81 0.33
38 INT240434 PPARA Negative_regulation of Gene_expression of CPOX 1 1 0.03 0.64 0.33
39 INT235430 Il13 Positive_regulation of Gene_expression of Olr1 1 1 0.00 2.12 0.33
40 INT215395 Csf2 Positive_regulation of Ppara 1 2 0.12 1.33 0.32
41 INT332972 Fas Positive_regulation of Ppara 1 2 0.17 0.52 0.31
42 INT122575 Akt1 Positive_regulation of Phosphorylation of Nos3 4 1 0.37 3.89 0.29
43 INT211997 CORD1 Positive_regulation of Rara 1 1 0.01 0.68 0.29
44 INT182499 Binding of AGTR1 and AGTR2 3 1 0.20 2.79 0.28
45 INT335134 PPARA Negative_regulation of Cyp1a1 1 1 0.47 0 0.28
46 INT301666 Binding of CYP4F2 and Ltb4r1 1 4 0.02 0.57 0.28
47 INT301668 Ltb4r1 Positive_regulation of Gene_expression of IL8 1 1 0.00 0.9 0.27
48 INT301671 Ltc4s Positive_regulation of Gene_expression of IL8 1 1 0.00 0.9 0.27
49 INT301670 Binding of CYP4F2 and Cyp4f18 1 1 0.02 1.04 0.27
50 INT329369 Jun Regulation of Gene_expression of Il12a 1 1 0.00 1.48 0.27
51 INT270046 Ido1 Positive_regulation of Positive_regulation of Hmox1 1 1 0.15 0.8 0.27
52 INT335130 PPARA Positive_regulation of Cyp8b1 1 1 0.37 0 0.27
53 INT237927 BCL2 Positive_regulation of BAX 2 1 0.24 2.22 0.26
54 INT237928 BCL2 Positive_regulation of FAS 1 1 0.02 1.41 0.26
55 INT237919 BAX Positive_regulation of Protein_catabolism of PARP1 1 1 0.03 1.41 0.26
56 INT237380 Binding of Cdkn2d and Il12b 1 1 0.01 0.45 0.26
57 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 1 0.02 1.42 0.26
58 INT335049 PPARA Negative_regulation of Gene_expression of CYP7B1 1 1 0.27 0 0.26
59 INT245072 PPARA Regulation of Gene_expression of CXCR4 1 1 0.07 0.68 0.26
60 INT335126 Ptgs2 Positive_regulation of Gene_expression of PPARA 1 1 0.24 0.72 0.25
61 INT297376 Binding of RARS and Rxra 1 2 0.01 3.27 0.24
62 INT329368 Ccl2 Negative_regulation of Jun 1 2 0.01 1.87 0.24
63 INT173120 Binding of PPARA and NR1H4 8 3 0.09 2.79 0.23
64 INT298785 PPARA Positive_regulation of ACOX1 3 3 0.29 1.58 0.23
65 INT238383 Tlr4 Positive_regulation of Ppara 1 1 0.17 0.41 0.23
66 INT215396 Il4 Positive_regulation of Gene_expression of Ppara 1 1 0.03 0.23 0.23
67 INT229702 Binding of Ppara and Ros1 1 1 0.01 1.05 0.23
68 INT207845 Binding of INS and Hypism 3 1 0.04 2.88 0.22
69 INT240539 Il12a Positive_regulation of Stat3 1 1 0.11 0.75 0.22
70 INT233929 PPARA Negative_regulation of ras 1 1 0.02 2.39 0.22
71 INT240538 Il12a Positive_regulation of Phosphorylation of Stat4 1 1 0.11 0.76 0.22
72 INT252357 Binding of THBS1 and Cd36 2 2 0.01 2.4 0.21
73 INT263339 Ptger2 Regulation of Ppara 1 4 0.09 0.44 0.21
74 INT240535 Il12a Positive_regulation of Tyk2 1 1 0.10 0.75 0.21
75 INT240536 Il12a Positive_regulation of Jak2 1 1 0.10 0.74 0.21
76 INT173430 Binding of FLT4 and VEGFA 10 2 0.25 9.38 0.19
77 INT217661 LEP Positive_regulation of INS 2 1 0.25 1.85 0.19
78 INT217665 ADIPOQ Positive_regulation of INS 2 1 0.06 1.8 0.19
79 INT298787 Binding of PPARA and TUSC5 1 2 0.32 1.38 0.19
80 INT298784 PPARA Positive_regulation of CPT1B 1 2 0.28 1.61 0.19
81 INT237924 PTPN1 Regulation of Gene_expression of CFLAR 1 1 0.01 0.7 0.19
82 INT335053 PPARA Positive_regulation of Gene_expression of LPL 1 1 0.21 0.34 0.19
83 INT192333 PDGFA Positive_regulation of Gene_expression of FN1 2 1 0.11 1.26 0.18
84 INT301615 Binding of Cyp2e1 and Samsn1 1 2 0.02 2.42 0.18
85 INT290672 Stat3 Negative_regulation of Il6 1 1 0.08 0.4 0.18
86 INT240435 JUN Positive_regulation of Gene_expression of CPOX 1 1 0.01 0.81 0.18
87 INT335046 PPARA Positive_regulation of Gene_expression of ABCA1 1 1 0.33 0.25 0.18
88 INT302295 PPARA Regulation of OAS2 1 1 0.01 0.72 0.17
89 INT335131 PPARA Negative_regulation of Gene_expression of Fgg 1 1 0.01 0.59 0.17
90 INT233904 NLRP3 Positive_regulation of AGT 1 1 0.06 0.81 0.17
91 INT278609 PPARA Positive_regulation of Gene_expression of SULT2A1 1 1 0.33 0 0.17
92 INT298641 PPARA Regulation of STAT3 1 1 0.23 0.98 0.16
93 INT235441 HMBS Regulation of PPARA 1 1 0.03 0.76 0.16
94 INT290670 Binding of Nos2 and Ppara 1 1 0.17 0.41 0.16
95 INT332968 Hoxb4 Positive_regulation of Ppara 1 1 0.02 0.25 0.16
96 INT335125 Me1 Positive_regulation of Localization of Fads2 1 1 0.07 0.09 0.16
97 INT329850 APOA5 Negative_regulation of Transcription of APOC3 1 1 0.24 0.85 0.15
98 INT278614 NR1I2 Regulation of Gene_expression of SULT2A1 1 2 0.11 0.11 0.15
99 INT298782 PPARA Positive_regulation of Gene_expression of TUSC5 1 2 0.42 0.62 0.15
100 INT298639 GDE1 Negative_regulation of AKT1 1 1 0.00 1.14 0.14
101 INT301638 Ppara Regulation of Slc27a2 1 1 0.30 0.29 0.14
102 INT215394 Binding of Csf2 and Positive_regulation of Ppara 1 1 0.12 0.49 0.14
103 INT276228 Nrtim1 Positive_regulation of PPARG 1 1 0.01 2.18 0.14
104 INT329847 PPARA Regulation of Gene_expression of CREB3L3 1 1 0.17 0.84 0.13
105 INT332966 Binding of Fas and Ppara 1 1 0.15 0.25 0.13
106 INT335128 G0s2 Negative_regulation of PNPLA2 1 1 0.10 0.4 0.13
107 INT329371 IL8 Negative_regulation of Jun 1 1 0.00 0.95 0.13
108 INT278610 CDCA2 Negative_regulation of NR1H4 1 1 0.01 0.62 0.13
109 INT227556 Ptgds Positive_regulation of Ppara 1 1 0.18 0.62 0.13
110 INT182886 Ros1 Positive_regulation of Mapk8 3 1 0.09 2.3 0.12
111 INT211996 Erbb3 Positive_regulation of Nrg1 2 1 0.03 0.67 0.11
112 INT256544 Pten Negative_regulation of Akt1 1 1 0.05 1.07 0.11
113 INT278607 SULT2A1 Positive_regulation of Binding of PPARA 1 1 0.24 0 0.11
114 INT298828 Binding of PPARA and Lpl 1 2 0.05 0.77 0.11
115 INT332893 Ppara Regulation of Gene_expression of Arntl 1 1 0.43 0 0.11
116 INT256545 Positive_regulation of Pten Negative_regulation of Akt1 1 1 0.05 1.07 0.11
117 INT240903 Mapk8 Positive_regulation of Ros1 2 1 0.09 1.01 0.1
118 INT301637 Positive_regulation of Ros1 Positive_regulation of Phosphorylation of Ins1 1 1 0.00 0.91 0.1
119 INT202619 Binding of Ppara and Spna1 1 1 0.01 0.27 0.1
120 INT332891 Per2 Positive_regulation of Ppara 1 1 0.43 0 0.1
121 INT263340 Ptger2 Positive_regulation of IL8 1 1 0.01 0.15 0.1
122 INT301660 Ppara Regulation of Gene_expression of CYP4A11 1 1 0.24 0.65 0.09
123 INT233858 CHKA Positive_regulation of Gene_expression of CDKN1B 1 1 0.10 0.17 0.09
124 INT298783 PPARA Positive_regulation of TUSC5 1 1 0.37 0.15 0.09
125 INT290673 Ppara Positive_regulation of Gtf3a 1 1 0.01 0.58 0.09
126 INT267156 Binding of VDR and SUGT1 1 2 0.04 3.4 0.09
127 INT298786 PPARA Positive_regulation of Transcription of CPT1B 1 1 0.17 0.93 0.09
128 INT298781 Positive_regulation of PPARA Positive_regulation of TUSC5 1 1 0.37 0.15 0.09
129 INT323071 Binding of RT1-DOa and Ppara 1 1 0.13 0.74 0.09
130 INT301663 Ppara Regulation of CYP4A11 1 1 0.14 0.65 0.09
131 INT290674 Ppara Positive_regulation of Gtf3a Positive_regulation of Ppara 1 1 0.01 0.58 0.09
132 INT234437 asa Negative_regulation of Ppara 1 1 0.13 0.4 0.09
133 INT173130 Binding of INS and PPARA 2 1 0.04 1.8 0.08
134 INT298634 Binding of IL6 and STAT3 1 2 0.04 1.41 0.08
135 INT233907 Positive_regulation of Binding of AGTR2 and NLRP3 1 1 0.01 1.09 0.08
136 INT238392 RB1 Regulation of E2F2 1 1 0.01 0.36 0.08
137 INT301655 Irs1 Negative_regulation of Transcription of Pck1 1 1 0.03 0.65 0.08
138 INT237922 TNFSF10 Positive_regulation of CDKN1A 1 2 0.09 3.28 0.08
139 INT301641 Irs2 Negative_regulation of Transcription of Pck1 1 1 0.03 0.65 0.08
140 INT335051 PPARA Positive_regulation of PCTP 1 1 0.10 0.38 0.08
141 INT301619 Positive_regulation of Irs1 Positive_regulation of Gene_expression of Srebf1 1 1 0.10 0.67 0.08
142 INT233906 Binding of AGTR2 and NLRP3 1 1 0.01 1.09 0.08
143 INT238397 EID1 Regulation of E2F2 1 1 0.00 0.36 0.08
144 INT301628 Irs2 Negative_regulation of Transcription of G6pc 1 1 0.04 0.65 0.08
145 INT301646 Srebf1 Negative_regulation of Gene_expression of Irs2 1 1 0.08 0.62 0.08
146 INT301613 Binding of Fabp4 and Cd36 1 1 0.05 0.38 0.08
147 INT267154 ADIPOQ Regulation of Positive_regulation of SUGT1 1 1 0.03 1.18 0.08
148 INT301645 Binding of Alb and Slc27a1 1 1 0.02 0.38 0.08
149 INT301631 Gene_expression of Mapk8 Positive_regulation of Phosphorylation of Irs1 1 1 0.09 0.72 0.08
150 INT229703 Binding of Ppara and Rxrg 1 1 0.03 0.08 0.08
151 INT301651 Binding of Alb and Fabp4 1 1 0.01 0.38 0.08
152 INT290669 Tlr4 Positive_regulation of Binding of Il6 1 1 0.02 0.07 0.08
153 INT301649 Irs1 Negative_regulation of Transcription of G6pc 1 1 0.05 0.65 0.08
154 INT278683 PPARA Regulation of Chst10 1 1 0.22 0.09 0.08
155 INT301614 Binding of Slc27a1 and Cd36 1 1 0.09 0.38 0.08
156 INT335132 PPARA Positive_regulation of Cyp4x1 1 1 0.25 0 0.08
157 INT301659 Gene_expression of Mapk8 Positive_regulation of Positive_regulation of Srebf1 1 1 0.33 0.8 0.08
158 INT301656 Ins1 Positive_regulation of Srebf1 1 2 0.02 0.73 0.07
159 INT278611 Binding of CASR and SULT2A1 1 1 0.03 0 0.07
160 INT278602 Binding of SULT2A1 and NR1I3 1 1 0.04 0 0.07
161 INT329897 PPARA Regulation of Cpt2 1 1 0.09 0.05 0.07
162 INT231440 PDGFA Positive_regulation of Gene_expression of HGF 1 1 0.16 0.83 0.07
163 INT329225 Prkag1 Positive_regulation of Akt1 1 1 0.09 1.27 0.07
164 INT231434 FN1 Positive_regulation of Gene_expression of PDGFA 1 1 0.04 0.83 0.07
165 INT278604 GSR Regulation of Gene_expression of SULT2A1 1 1 0.02 0.05 0.07
166 INT301623 Ins1 Positive_regulation of Slc27a2 1 1 0.01 0.37 0.07
167 INT278684 Binding of NR1I3 and Rxra 1 1 0.00 0 0.07
168 INT236932 Binding of Rxra and Pprc1 1 1 0.00 0.45 0.07
169 INT335129 PPARA Positive_regulation of Gene_expression of Insig1 1 1 0.20 0.15 0.07
170 INT231436 FN1 Positive_regulation of Gene_expression of VEGFA 1 1 0.06 0.83 0.07
171 INT234381 Binding of CD40 and PPARA 1 1 0.19 1.39 0.07
172 INT236936 Ppara Positive_regulation of Mapk1 1 2 0.09 0.64 0.07
173 INT279652 PPARA Positive_regulation of Gene_expression of Apoa1 1 1 0.00 0.75 0.07
174 INT278600 Binding of CASR and SULT2A1 Positive_regulation of SULT2A1 1 1 0.03 0 0.07
175 INT301632 Binding of Dbi and Fabp1 1 1 0.13 0.49 0.07
176 INT278685 Binding of CASR and Rxra 1 1 0.00 0 0.07
177 INT278613 NR3C1 Regulation of Gene_expression of SULT2A1 1 1 0.02 0.05 0.07
178 INT301658 Ins1 Positive_regulation of Slc27a4 1 1 0.01 0.37 0.07
179 INT231442 FN1 Positive_regulation of Gene_expression of HGF 1 1 0.05 0.83 0.07
180 INT231441 PDGFA Positive_regulation of Gene_expression of VEGFA 1 1 0.17 0.83 0.07
181 INT332897 Ppara Regulation of Transcription of Clock 1 1 0.24 0.31 0.06
182 INT339711 TRO Regulation of PPARA 1 1 0.09 0.97 0.06
183 INT332880 Arntl Regulation of Ppara 1 2 0.29 0 0.06
184 INT278601 NR1I2 Negative_regulation of Gene_expression of SULT2A1 1 1 0.10 0 0.06
185 INT285383 Cars Regulation of Regulation of Sult1a1 1 1 0.01 0 0.06
186 INT236938 Binding of Akt1 and SPNS1 1 2 0.00 0.72 0.06
187 INT285382 Nat2 Positive_regulation of Localization of Chst10 1 1 0.03 0.08 0.06
188 INT285381 Scn11a Positive_regulation of Localization of Chst10 1 1 0.12 0.08 0.06
189 INT242035 Binding of SNRNP70 and CHDH 1 1 0.02 3.41 0.06
190 INT236147 Binding of Ins1 and Ptpn1 2 1 0.03 1.29 0.05
191 INT278606 CASR Regulation of SULT2A1 1 1 0.04 0 0.05
192 INT256548 Regulation of Cd320 Positive_regulation of Ppara 1 1 0.28 0.43 0.05
193 INT298638 IL6 Positive_regulation of IL6R 1 1 0.00 0.9 0.05
194 INT278612 NR1I2 Regulation of SULT2A1 1 1 0.13 0 0.05
195 INT298806 Binding of Hdac3 and Rb1 1 2 0.02 0.77 0.05
196 INT285384 Binding of Rare1 and Rxra 1 1 0.01 0.08 0.05
197 INT332900 Ppara Regulation of Clock 1 1 0.21 0 0.05
198 INT335047 PPARA Positive_regulation of Gene_expression of APOA1 1 1 0.20 0.42 0.05
199 INT267152 Binding of LEP and DDX12P 1 1 0.00 0.69 0.05
200 INT329218 Phosphorylation of Ppara Positive_regulation of Prkag1 1 1 0.34 0.2 0.05

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 6 3152 0.78 2515.62 929.82
2 INT9238 Gene_expression of IL6 11 1575 0.78 1135.66 424.22
3 INT5235 Negative_regulation of TNF 2 924 0.59 772.91 331.98
4 INT5059 Positive_regulation of TNF 2 1050 0.70 896.51 322.81
5 INT49750 Negative_regulation of CPOX 18 735 0.58 360.06 274.19
6 INT6852 Localization of TNF 1 883 0.81 705.95 270.84
7 INT10832 Gene_expression of IL8 13 1050 0.78 698.72 270
8 INT9659 Gene_expression of Il6 10 991 0.78 715.11 265.57
9 INT68684 Gene_expression of VEGFA 58 2371 0.78 1742.52 259.2
10 INT87687 Positive_regulation of Trpv1 1 409 0.70 210.24 257.59
11 INT16868 Gene_expression of Il6 1 807 0.78 499.48 256.57
12 INT95787 Positive_regulation of Mapk1 11 568 0.70 226.51 220.94
13 INT6482 Positive_regulation of Gene_expression of TNF 1 659 0.70 569.88 210
14 INT48955 Gene_expression of Nos2 5 753 0.78 403.87 208.08
15 INT2391 Negative_regulation of PTGS1 1 501 0.59 207.62 205.6
16 INT11313 Positive_regulation of Il6 1 526 0.70 331.27 201.59
17 INT50670 Gene_expression of CPOX 40 763 0.76 442.13 195.02
18 INT24326 Gene_expression of Ngf 4 346 0.78 218.67 184.71
19 INT10194 Positive_regulation of IL6 3 702 0.70 600.62 183.38
20 INT49441 Negative_regulation of Cpox 3 494 0.59 303.22 177.46
21 INT19472 Gene_expression of Il1 4 554 0.76 419.75 175.35
22 INT15516 Gene_expression of Crp 1 711 0.77 615.33 173.09
23 INT867 Gene_expression of IFNA1 5 930 0.78 594.85 168.03
24 INT1114 Localization of Ins1 2 748 0.80 192.95 165.48
25 INT66280 Gene_expression of Nos2 25 534 0.78 330.78 157.07
26 INT15515 Positive_regulation of Crp 1 700 0.70 604.24 150.15
27 INT9852 Positive_regulation of Gpt 1 563 0.70 364.64 146.82
28 INT5116 Gene_expression of IL2 2 670 0.78 291.13 146.69
29 INT812 Localization of INS 3 1026 0.81 515.6 145.31
30 INT60694 Gene_expression of Il10 6 567 0.78 369.48 143.69
31 INT48953 Positive_regulation of Nos2 1 486 0.70 239.85 131.87
32 INT49439 Gene_expression of Cpox 15 508 0.73 326.97 130.17
33 INT64161 Positive_regulation of Prkca 1 213 0.70 85.06 129.91
34 INT115386 Gene_expression of Ppara 527 779 0.77 549.99 128.36
35 INT65600 Positive_regulation of Casp3 2 376 0.70 198.44 128.03
36 INT7533 Gene_expression of Tlr4 3 720 0.78 343.22 121.57
37 INT14151 Gene_expression of Casp3 1 311 0.78 140.26 120.68
38 INT8243 Positive_regulation of Il6 2 451 0.70 358.24 119.28
39 INT17612 Gene_expression of CRP 2 676 0.78 580.61 119.03
40 INT9235 Negative_regulation of Gene_expression of TNF 1 346 0.59 252.98 118.61
41 INT50674 Gene_expression of PTGS2 6 459 0.78 253.33 118.51
42 INT12339 Localization of IL8 2 437 0.81 251.87 117.39
43 INT62124 Gene_expression of NOS1 3 444 0.78 218.08 114.85
44 INT48593 Positive_regulation of NOS1 3 420 0.68 226.15 114.71
45 INT20374 Gene_expression of Il4 5 515 0.76 306.15 114.12
46 INT65731 Gene_expression of Cnr1 2 234 0.78 63.82 109.34
47 INT11051 Positive_regulation of Gene_expression of IL6 5 415 0.69 319.21 109.3
48 INT27096 Positive_regulation of Nfkb1 1 325 0.70 195.11 109.06
49 INT3038 Gene_expression of INS 16 1583 0.78 1174.16 107.01
50 INT12082 Localization of IL6 6 365 0.81 241.78 105.78
51 INT49171 Gene_expression of Nos1 1 241 0.78 140.7 104.76
52 INT69440 Gene_expression of ROS1 14 752 0.78 477.64 103.83
53 INT10838 Positive_regulation of IL8 3 381 0.70 295.51 101.62
54 INT74826 Gene_expression of Slc1a2 1 131 0.78 61.83 100.84
55 INT65500 Gene_expression of App 5 605 0.78 429.94 98.31
56 INT1760 Gene_expression of PTGER2 5 524 0.57 226.94 96.4
57 INT940 Negative_regulation of Ptgs1 2 219 0.59 104.34 95.97
58 INT77435 Positive_regulation of Nos2 7 343 0.70 208.49 91.43
59 INT86024 Gene_expression of PPARA 464 736 0.78 497.93 91.14
60 INT48767 Negative_regulation of NOS1 1 312 0.59 154.25 90.32
61 INT71789 Positive_regulation of MAPK1 2 396 0.70 234.44 89.27
62 INT96917 Positive_regulation of Mapk14 2 261 0.70 173.29 88.79
63 INT48408 Gene_expression of ICAM1 1 494 0.78 340.08 88.6
64 INT7180 Negative_regulation of Trib3 1 180 0.51 68.48 88.01
65 INT1472 Positive_regulation of Ins1 1 349 0.69 146.2 86.36
66 INT92434 Phosphorylation of Mapk1 6 287 0.82 91.65 83.46
67 INT84546 Positive_regulation of Ppara 322 481 0.70 334.21 83.45
68 INT48406 Gene_expression of Icam1 2 277 0.78 238.28 81.71
69 INT68682 Positive_regulation of VEGFA 17 640 0.70 454.14 81.65
70 INT56291 Gene_expression of Ros1 23 503 0.63 274.12 81.5
71 INT10534 Positive_regulation of Trib3 1 209 0.60 78.75 81.48
72 INT1498 Gene_expression of Gh 1 521 0.75 220.84 81.16
73 INT3214 Localization of Ins1 9 527 0.80 196.9 79.26
74 INT60691 Gene_expression of Il12a 25 331 0.78 208.03 75.96
75 INT3657 Gene_expression of Ins1 2 514 0.78 321.69 75.76
76 INT1724 Negative_regulation of ACE 1 437 0.59 315.64 74.48
77 INT9236 Regulation of Gene_expression of TNF 1 204 0.62 162.66 72.99
78 INT56298 Gene_expression of IL4 3 306 0.78 182.18 72.92
79 INT39565 Gene_expression of Ptger2 8 424 0.75 229.28 72.68
80 INT6490 Negative_regulation of ADCY1 1 145 0.58 26.25 70.96
81 INT15913 Negative_regulation of CYP2D6 1 174 0.59 22.45 70.91
82 INT10837 Positive_regulation of Gene_expression of IL8 6 294 0.70 190.08 70.34
83 INT79494 Positive_regulation of Gene_expression of VEGFA 19 577 0.70 442.94 69.73
84 INT170332 Gene_expression of IFN1@ 1 477 0.75 275.21 69.65
85 INT1988 Positive_regulation of Localization of Ins1 1 254 0.69 59.25 68.37
86 INT102546 Gene_expression of Ccl2 7 197 0.78 192.8 67.41
87 INT5374 Gene_expression of Esr1 6 412 0.77 263.89 67.34
88 INT65733 Positive_regulation of Cnr1 1 125 0.70 40.27 67.33
89 INT1046 Gene_expression of LH 1 180 0.77 29.75 66.87
90 INT11807 Gene_expression of Il2 6 266 0.78 112 64.97
91 INT1599 Positive_regulation of ADCY1 1 146 0.67 30.05 64.9
92 INT15514 Negative_regulation of Crp 3 275 0.59 194.6 64.86
93 INT11937 Localization of Il6 3 228 0.81 139.83 64.39
94 INT822 Gene_expression of ESR1 1 529 0.78 302.16 63.64
95 INT67614 Positive_regulation of PPARA 263 438 0.68 293.28 63.61
96 INT9657 Positive_regulation of Gene_expression of Il6 4 237 0.70 180.45 63.6
97 INT1951 Positive_regulation of Tlr4 5 345 0.70 176.99 62.42
98 INT17401 Gene_expression of IGF1 1 475 0.78 232.18 62.07
99 INT11318 Gene_expression of Gtf3a 3 274 0.52 183.82 60.89
100 INT39153 Positive_regulation of PTGS2 3 182 0.70 96.16 60.6
101 INT5058 Positive_regulation of IFNA1 1 356 0.70 245.75 60.52
102 INT9196 Gene_expression of PTGS1 1 215 0.77 96.99 60.5
103 INT17564 Gene_expression of Gpt 1 322 0.75 208.51 60.36
104 INT103924 Positive_regulation of Akt1 5 359 0.69 158.94 60.34
105 INT50672 Positive_regulation of CPOX 5 205 0.44 125.93 60.06
106 INT55344 Gene_expression of Ros1 2 396 0.54 217.64 59.98
107 INT1759 Gene_expression of TIMP1 1 267 0.77 133.87 59.29
108 INT3920 Localization of Ldha 1 241 0.81 83.08 58.72
109 INT48901 Negative_regulation of IL6 1 186 0.57 136.33 57.87
110 INT73048 Gene_expression of MMP9 3 268 0.77 159.75 57.81
111 INT96937 Gene_expression of Mmp9 5 191 0.75 150.3 56.01
112 INT52692 Gene_expression of Ptgs2 1 160 0.78 85.06 55.73
113 INT314 Positive_regulation of Ren 1 212 0.70 66.68 55.56
114 INT251 Regulation of INS 13 398 0.62 232.47 55.04
115 INT82650 Gene_expression of Bcl2 5 312 0.78 211.71 55.03
116 INT63975 Positive_regulation of Il10 5 175 0.68 134.13 54.69
117 INT20375 Gene_expression of Hand1 7 213 0.60 148.51 54.53
118 INT117713 Phosphorylation of Akt1 1 275 0.82 95.82 54.34
119 INT2276 Regulation of Ins1 1 234 0.61 103.78 54.05
120 INT3213 Gene_expression of Ins1 11 511 0.76 357.59 53.32
121 INT96914 Phosphorylation of Mapk14 1 168 0.82 108.46 53.32
122 INT48952 Negative_regulation of Nos2 1 204 0.59 101.73 53.15
123 INT9234 Negative_regulation of Gene_expression of IL6 4 171 0.59 101.61 53.15
124 INT62543 Gene_expression of Icam1 9 231 0.78 187.58 52.71
125 INT49017 Negative_regulation of Gene_expression of Nos2 3 169 0.59 80.64 52.67
126 INT22112 Positive_regulation of Localization of TNF 1 164 0.70 115.66 52.18
127 INT72182 Gene_expression of Mcpt1 4 167 0.75 123.7 52.15
128 INT22546 Positive_regulation of Gene_expression of Casp3 1 97 0.70 47.89 51.92
129 INT64110 Positive_regulation of Gene_expression of Nos1 1 68 0.70 58.11 51.64
130 INT50405 Negative_regulation of CYP3A4 2 238 0.59 53.65 51.51
131 INT122041 Binding of Ppara 240 308 0.48 189.17 51.48
132 INT20382 Gene_expression of Hand2 5 211 0.66 142.26 51.05
133 INT19775 Localization of Il1 1 183 0.78 145.5 50.91
134 INT74827 Positive_regulation of Gene_expression of Slc1a2 1 52 0.70 26.54 50.63
135 INT1199 Positive_regulation of INS 8 579 0.70 399.64 50.43
136 INT53083 Gene_expression of Ptgs2 1 153 0.78 90.04 50.39
137 INT40777 Positive_regulation of Akt1 2 163 0.69 59.41 49.43
138 INT7093 Negative_regulation of CYP2B6 1 146 0.58 37.3 48.39
139 INT17881 Gene_expression of LEP 7 278 0.78 221.61 48.31
140 INT106525 Phosphorylation of Akt1 6 436 0.82 183.81 47.82
141 INT375 Positive_regulation of REN 1 293 0.70 152.46 47.55
142 INT26500 Gene_expression of MMP2 3 201 0.78 110.57 46.9
143 INT30170 Gene_expression of Car2 1 330 0.66 77.26 46.76
144 INT71786 Phosphorylation of MAPK1 3 256 0.82 110.09 46.17
145 INT1322 Positive_regulation of Localization of INS 1 293 0.70 120.86 45.98
146 INT18522 Positive_regulation of Gene_expression of IFNA1 1 248 0.67 160.85 44.87
147 INT27493 Negative_regulation of Casp3 1 114 0.56 56.89 44.63
148 INT63383 Binding of Cnr1 5 77 0.48 22.28 44.61
149 INT80124 Negative_regulation of VEGFA 11 450 0.58 311.19 44.53
150 INT98498 Binding of Trpv1 2 75 0.48 33.67 44.4
151 INT4216 Gene_expression of CD40LG 1 328 0.78 256.02 44.23
152 INT100939 Gene_expression of Il13 4 176 0.73 125.1 43.38
153 INT66383 Phosphorylation of Prkaca 2 143 0.80 30.85 43.38
154 INT25383 Gene_expression of Csf2 2 222 0.76 152.93 43.32
155 INT60695 Positive_regulation of Gene_expression of Il10 1 154 0.70 120.28 43.07
156 INT115384 Positive_regulation of Mmp9 1 121 0.68 94.74 43.02
157 INT49105 Gene_expression of Vcam1 2 157 0.78 157.27 43.01
158 INT52531 Gene_expression of Nfkb1 1 153 0.75 82.84 42.9
159 INT613 Gene_expression of Alb 1 268 0.78 149.84 42.78
160 INT85943 Negative_regulation of Nos2 3 161 0.59 108.56 42.65
161 INT13556 Gene_expression of CD4 1 367 0.78 230.82 41.74
162 INT65245 Gene_expression of Nos3 3 121 0.78 98.14 41.56
163 INT11939 Negative_regulation of Il6 1 138 0.59 87.46 41.24
164 INT69437 Positive_regulation of ROS1 6 328 0.58 222.83 40.56
165 INT52732 Negative_regulation of CRP 3 169 0.59 138.47 40.33
166 INT92437 Positive_regulation of Phosphorylation of Mapk1 1 113 0.70 32.19 40.29
167 INT114751 Gene_expression of Mapk1 9 137 0.76 60.14 39.98
168 INT89661 Gene_expression of Hrec 3 102 0.21 69.91 39.57
169 INT3252 Negative_regulation of INS 1 428 0.59 271.65 39.52
170 INT11560 Positive_regulation of CASP3 3 236 0.70 184.33 39.38
171 INT102611 Negative_regulation of Positive_regulation of Mapk1 2 74 0.58 35.57 39.37
172 INT77434 Positive_regulation of Gene_expression of Nos2 5 151 0.69 96.76 38.94
173 INT20210 Localization of Ngf 2 69 0.79 46.22 38.57
174 INT68975 Gene_expression of Mmp9 1 111 0.78 79.57 38.55
175 INT55135 Positive_regulation of Gene_expression of PTGS2 2 137 0.70 80.32 38.46
176 INT77307 Gene_expression of Bcl2 6 399 0.77 319.77 38
177 INT56870 Gene_expression of CYP2D6 1 87 0.78 8.83 37.53
178 INT50673 Positive_regulation of Gene_expression of CPOX 10 156 0.54 97.31 37.03
179 INT104551 Gene_expression of Il18 1 156 0.76 115.51 36.95
180 INT63349 Gene_expression of PECAM1 1 199 0.75 166.03 36.76
181 INT3253 Negative_regulation of Localization of INS 1 205 0.59 130.39 36.61
182 INT133028 Gene_expression of TLR2 1 209 0.73 131.92 36.17
183 INT101992 Localization of VEGFA 11 413 0.81 258.23 36.15
184 INT70437 Negative_regulation of Mdk 3 115 0.57 41.03 35.72
185 INT3216 Positive_regulation of Localization of Ins1 6 170 0.69 56.78 35.63
186 INT10796 Gene_expression of CYP2B6 16 131 0.77 30.14 35.27
187 INT8747 Positive_regulation of Ins1 8 221 0.69 154.28 35.15
188 INT118343 Positive_regulation of Eae1 2 121 0.39 136.06 34.87
189 INT20380 Gene_expression of Il5 2 172 0.78 104.75 34.78
190 INT103094 Binding of PPARA 212 308 0.47 177.26 34.75
191 INT66005 Regulation of Cnr1 1 47 0.61 19.21 34.52
192 INT67613 Positive_regulation of PPARG 9 94 0.70 69.15 34.38
193 INT14559 Gene_expression of Igf1 1 254 0.78 112 34.17
194 INT104392 Gene_expression of Cxcl10 3 113 0.75 106.86 34.12
195 INT74563 Positive_regulation of Gene_expression of ROS1 6 258 0.61 168.18 34.08
196 INT81289 Positive_regulation of Gene_expression of Tlr4 1 192 0.69 104.5 33.89
197 INT4403 Binding of CYP2B6 3 113 0.48 21.17 33.83
198 INT67039 Positive_regulation of Cpox 3 144 0.65 98.4 33.77
199 INT666 Gene_expression of Jun 3 124 0.78 54.61 33.67
200 INT84825 Gene_expression of CD36 3 121 0.78 43.73 33.23
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