J:Perspectives in Medicinal Chemistry

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT283183 Binding of S100A4 and ZAK 1 1 0.06 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT4941 Positive_regulation of Oprd1 1 345 0.70 74.26 304.41
2 INT11624 Gene_expression of OPRM1 1 445 0.78 72.36 294.36
3 INT68684 Gene_expression of VEGFA 1 2371 0.78 1742.52 259.2
4 INT14843 Gene_expression of Gabrg1 3 301 0.77 62.63 139.16
5 INT695 Binding of POMC 1 304 0.48 56.66 126.85
6 INT90091 Gene_expression of GOPC 1 967 0.67 366.22 103.6
7 INT4960 Positive_regulation of CSF2 2 285 0.70 256.73 65.73
8 INT18981 Gene_expression of ABAT 5 78 0.68 38.35 61.36
9 INT2761 Regulation of Gabrg1 1 119 0.61 18.8 60.52
10 INT103924 Positive_regulation of Akt1 1 359 0.69 158.94 60.34
11 INT6034 Binding of Gabrg1 5 115 0.47 17.48 51.92
12 INT19488 Localization of ABAT 2 56 0.69 21.51 50.56
13 INT173693 Localization of Gopc 1 249 0.65 70.49 38.81
14 INT6417 Negative_regulation of ABAT 10 49 0.51 19.6 36.81
15 INT3913 Positive_regulation of ABAT 1 47 0.69 22.73 33.4
16 INT11554 Negative_regulation of CSF2 1 129 0.59 108.55 29.44
17 INT11796 Positive_regulation of Helt 1 52 0.31 11.7 29.22
18 INT13995 Gene_expression of gr 1 96 0.74 48.21 26.54
19 INT79395 Gene_expression of Twist1 1 193 0.77 100.06 26.34
20 INT172458 Regulation of Gopc 1 155 0.53 62.57 24.86
21 INT134651 Binding of TLR4 1 89 0.48 66.96 23.19
22 INT170444 Binding of Gopc 1 172 0.39 45.05 20.71
23 INT1756 Negative_regulation of DNAH8 1 105 0.59 42.73 20.24
24 INT18621 Binding of ABAT 3 28 0.36 9.88 18.04
25 INT95790 Regulation of Mapk1 1 55 0.61 21.17 16.31
26 INT18012 Gene_expression of EPO 2 169 0.78 108.36 13.75
27 INT158070 Localization of Aes 1 23 0.65 19.93 10.9
28 INT1108 Gene_expression of PPY 9 58 0.75 36.57 10.76
29 INT3180 Positive_regulation of PPY 13 39 0.63 25.57 10.15
30 INT134625 Gene_expression of Kdr 2 116 0.71 53.13 10.09
31 INT45812 Protein_catabolism of Gabrg1 3 12 0.79 1.93 8.76
32 INT144430 Gene_expression of Erbb2 1 137 0.77 103.87 8.66
33 INT43820 Positive_regulation of Twist1 1 75 0.59 42.15 8.47
34 INT155989 Negative_regulation of Localization of ABAT 1 7 0.38 1.29 6.95
35 INT31226 Localization of PPY 1 20 0.78 9.93 6.8
36 INT49212 Negative_regulation of GAD1 1 23 0.59 22.15 6.54
37 INT7205 Positive_regulation of HBG1 1 65 0.69 40.35 6.37
38 INT39758 Gene_expression of Fn1 1 57 0.65 34.38 6.02
39 INT28164 Regulation of ALOX5 1 25 0.60 12.76 5.47
40 INT94028 Regulation of Twist1 1 37 0.44 22.41 5.33
41 INT6881 Binding of Tspo 1 12 0.46 5.03 4.38
42 INT106318 Gene_expression of S100A4 4 21 0.75 12.13 3.23
43 INT141452 Negative_regulation of Binding of ABAT 1 4 0.37 1.41 3.17
44 INT165057 Binding of MID1 1 7 0.32 4.13 3.12
45 INT32852 Negative_regulation of FECH 1 18 0.57 10.59 3.08
46 INT172177 Protein_catabolism of INCENP 1 18 0.37 6.34 2.91
47 INT239083 Binding of PPY 4 9 0.32 7.59 2.9
48 INT80435 Negative_regulation of Positive_regulation of ABAT 1 2 0.34 0.69 2.45
49 INT156373 Binding of Sv2a 2 4 0.39 1.54 2.3
50 INT134626 Positive_regulation of Gene_expression of Kdr 1 20 0.63 14.63 2.29
51 INT128453 Positive_regulation of S100A4 1 8 0.67 3.24 1.84
52 INT275875 Negative_regulation of Localization of Aes 1 2 0.19 3.87 1.8
53 INT85608 Negative_regulation of SLC6A1 1 3 0.53 1.76 1.66
54 INT992 Regulation of S100A4 16 21 0.60 1.47 1.46
55 INT74178 Gene_expression of HMBS 1 24 0.76 9.62 1.36
56 INT326168 Negative_regulation of Localization of SLC6A1 1 1 0.07 0.78 1.24
57 INT326169 Localization of SLC6A1 1 1 0.13 0.72 1.24
58 INT215091 Regulation of Localization of Gopc 1 6 0.27 1.18 1.2
59 INT112991 Positive_regulation of Gene_expression of PPY 4 7 0.29 6.26 0.99
60 INT39269 Positive_regulation of Negative_regulation of CSF2 1 3 0.28 1.28 0.88
61 INT176445 Protein_catabolism of Gopc 1 23 0.76 7.57 0.75
62 INT50291 Positive_regulation of HMBS 2 10 0.67 8.89 0.73
63 INT125331 Gene_expression of BOC 1 4 0.58 0 0.69
64 INT51336 Binding of Vtn 1 3 0.12 1.5 0.66
65 INT38834 Positive_regulation of Positive_regulation of PPY 7 2 0.42 4.18 0.61
66 INT151663 Regulation of Gsk3a 1 3 0.16 1.03 0.54
67 INT134208 Negative_regulation of Ptk2 1 19 0.58 23.59 0.52
68 INT172558 Positive_regulation of Cdh1 1 11 0.49 8.92 0.42
69 INT207081 Binding of Plaur 1 6 0.31 5.99 0.41
70 INT271521 Phosphorylation of Ptk2 1 10 0.59 11.45 0.39
71 INT128450 Transcription of S100A4 1 2 0.67 0.25 0.31
72 INT142132 Positive_regulation of Erbb3 1 3 0.27 0.82 0.3
73 INT271522 Negative_regulation of Phosphorylation of Ptk2 1 3 0.19 2.09 0.26
74 INT176500 Negative_regulation of KLK5 1 3 0.26 0.41 0.24
75 INT176497 Regulation of KLK5 1 2 0.28 0.45 0.22
76 INT231264 Gene_expression of Erbb3 1 9 0.35 1.45 0.15
77 INT200942 Gene_expression of FDFT1 1 3 0.35 0.5 0.15
78 INT283174 Negative_regulation of Gene_expression of BOC 1 1 0.04 0 0.15
79 INT176501 Binding of KLK5 1 2 0.23 0.17 0.14
80 INT154540 Regulation of Gene_expression of PPY 1 2 0.10 1.08 0.13
81 INT282445 Negative_regulation of Binding of Vtn 1 1 0.15 0.63 0.11
82 INT283190 Negative_regulation of ATP2A1 1 1 0.42 0.43 0.07
83 INT283191 Negative_regulation of Gene_expression of FDFT1 2 1 0.02 0.34 0.07
84 INT176499 Localization of KLK5 1 2 0.43 0.13 0.04
85 INT176496 Gene_expression of KLK5 1 4 0.41 0.22 0
86 INT176498 Positive_regulation of Gene_expression of KLK5 1 2 0.31 0.14 0
87 INT282444 Regulation of Gene_expression of Erbb3 1 1 0.11 0.84 0
88 INT282449 Regulation of Positive_regulation of Erbb3 1 1 0.11 0.91 0
89 INT283176 Positive_regulation of Binding of PPY 1 1 0.01 0.06 0
90 INT282448 Protein_catabolism of Gabra6 1 1 0.14 1 0
91 INT283188 Binding of S100A4 3 1 0.18 0 0
92 INT283175 Negative_regulation of Binding of PPY 1 1 0.01 0.2 0
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