J:Pharm. Res.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT35963 Binding of ALB and MPG 1 1 0.40 0 0.3
2 INT54095 ERAP1 Regulation of Protein_catabolism of Fgg 1 1 0.00 0 0.09
3 INT54096 NRG1 Regulation of Protein_catabolism of Fgg 1 1 0.01 0 0.09
4 INT125643 Cyp2e1 Positive_regulation of Transcription of Cyp2c11 1 2 0.51 0 0
5 INT125656 Cyp2e1 Positive_regulation of Transcription of Cyp2b2 1 2 0.07 0 0
6 INT86001 Binding of Pnp and Alms1 1 1 0.03 0 0
7 INT125648 Cyp2c11 Positive_regulation of Transcription of Cyp3a23/3a1 1 2 0.42 0 0
8 INT125646 Cyp2b2 Positive_regulation of Transcription of Cyp2e1 1 2 0.07 0 0
9 INT125642 Cyp2b2 Positive_regulation of Transcription of Cyp2c6 1 1 0.06 0 0
10 INT125655 Cyp2c6 Positive_regulation of Transcription of Cyp2b2 1 1 0.06 0 0
11 INT125647 Cyp2c11 Positive_regulation of Transcription of Cyp2b2 1 2 0.07 0 0
12 INT125652 Cyp2c6 Positive_regulation of Transcription of Cyp2e1 1 2 0.49 0 0
13 INT125658 Cyp2c6 Positive_regulation of Transcription of Cyp2c11 1 1 0.47 0 0
14 INT86004 Binding of PBCA and Alms1 1 1 0.01 0 0
15 INT125659 Cyp2b2 Positive_regulation of Transcription of Cyp3a23/3a1 1 1 0.06 0 0
16 INT125650 Cyp2e1 Positive_regulation of Transcription of Cyp2c6 1 2 0.49 0 0
17 INT125661 Cyp2c11 Positive_regulation of Transcription of Cyp2e1 1 4 0.51 0 0
18 INT125657 Cyp2b2 Positive_regulation of Transcription of Cyp2c11 1 1 0.07 0 0
19 INT125654 Cyp2e1 Positive_regulation of Transcription of Cyp3a23/3a1 1 2 0.43 0 0
20 INT95055 Binding of CYP1A2 and TXNRD1 1 1 0.04 0 0
21 INT125649 Cyp2c6 Positive_regulation of Transcription of Cyp3a23/3a1 1 1 0.40 0 0
22 INT125651 Cyp2c11 Positive_regulation of Transcription of Cyp2c6 1 2 0.47 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT728 Positive_regulation of Penk 2 1068 0.70 186.9 636.87
2 INT1395 Negative_regulation of Penk 1 537 0.59 87.33 389.81
3 INT5660 Binding of Oprd1 1 477 0.48 71.86 342.06
4 INT16868 Gene_expression of Il6 1 807 0.78 499.48 256.57
5 INT48955 Gene_expression of Nos2 5 753 0.78 403.87 208.08
6 INT5061 Negative_regulation of Mme 1 306 0.59 51.97 136.9
7 INT48953 Positive_regulation of Nos2 4 486 0.70 239.85 131.87
8 INT114 Binding of Oprl1 1 139 0.48 23 103.35
9 INT293 Protein_catabolism of Penk 4 161 1.00 11.71 98.45
10 INT48767 Negative_regulation of NOS1 1 312 0.59 154.25 90.32
11 INT64636 Positive_regulation of Gene_expression of Nos2 5 242 0.70 147.52 79.53
12 INT8962 Gene_expression of Cpe 2 110 0.71 39.67 71.67
13 INT546 Binding of ALB 4 311 0.48 85.98 60.14
14 INT21737 Binding of MC1R 1 129 0.48 45.45 56.54
15 INT48952 Negative_regulation of Nos2 1 204 0.59 101.73 53.15
16 INT49017 Negative_regulation of Gene_expression of Nos2 3 169 0.59 80.64 52.67
17 INT724 Negative_regulation of Alb 1 151 0.59 93.57 29.65
18 INT10684 Negative_regulation of Protein_catabolism of Penk 2 41 0.59 2.33 28.63
19 INT5232 Negative_regulation of Enpep 3 56 0.57 3.25 26.7
20 INT50490 Regulation of PTGS2 1 80 0.48 39.51 25.85
21 INT61953 Transcription of Nos2 3 101 0.72 46.64 25.49
22 INT70503 Regulation of Gene_expression of Nos2 2 71 0.62 44 24.01
23 INT90300 Gene_expression of Abcb1a 3 56 0.78 11.05 22.89
24 INT52457 Gene_expression of ABCB1 7 129 0.78 38.68 19.88
25 INT73362 Negative_regulation of Abcb1a 6 46 0.59 8.78 17.81
26 INT61949 Regulation of Nos2 1 74 0.58 34.08 16.7
27 INT15166 Positive_regulation of Mme 1 40 0.70 13.01 16.24
28 INT7952 Localization of Slc3a1 1 32 0.81 1.28 15.69
29 INT83682 Positive_regulation of Abcb1a 1 22 0.68 3.3 15.6
30 INT1850 Binding of OXA1L 3 77 0.48 7.61 15.22
31 INT18191 Negative_regulation of Cyp3a23/3a1 3 48 0.57 10.21 13.38
32 INT48956 Negative_regulation of Positive_regulation of Nos2 1 34 0.46 13.15 11.15
33 INT70850 Positive_regulation of Transcription of Nos2 1 30 0.70 18.95 9.68
34 INT41569 Regulation of APP 1 32 0.62 17.15 9.4
35 INT57665 Negative_regulation of Cyp2e1 3 35 0.59 8.05 9.29
36 INT13467 Positive_regulation of ABCB1 2 36 0.68 9.68 8.95
37 INT82839 Negative_regulation of ABCB1 7 61 0.59 16.09 8.83
38 INT21438 Binding of Trim13 1 10 0.47 0.26 8.76
39 INT9968 Negative_regulation of Rab38 2 15 0.00 10.45 8.64
40 INT49983 Negative_regulation of Aap 1 12 0.58 3.16 7.92
41 INT10284 Binding of ORM1 1 16 0.48 0.98 7.73
42 INT13675 Gene_expression of Cyp2c22 2 23 0.39 4.52 7.71
43 INT80981 Regulation of Abcb1a 4 19 0.62 1.86 7.2
44 INT612 Positive_regulation of Orm1 1 15 0.68 5.24 6.73
45 INT59079 Transcription of PTGS2 1 30 0.72 14.21 6.52
46 INT89084 Gene_expression of Slco1c1 1 15 0.51 4.92 6.02
47 INT57719 Localization of GPM6A 1 7 0.44 0.95 5.97
48 INT2552 Binding of Fdft1 1 6 0.15 0.48 5.88
49 INT68899 Binding of CYP1A2 1 19 0.48 2.33 5.73
50 INT3811 Negative_regulation of PAEP 1 36 0.50 23.7 5.18
51 INT96198 Positive_regulation of Gene_expression of ABCB1 4 25 0.68 5.89 5.15
52 INT119909 Binding of Abcb1a 1 10 0.36 0.76 5.07
53 INT12412 Binding of MPG 2 21 0.47 3.92 4.94
54 INT55419 Regulation of CYP1A2 1 19 0.62 5.3 4.75
55 INT54257 Binding of H2-M3 1 5 0.03 0.71 4.68
56 INT3128 Negative_regulation of PON1 1 30 0.59 26.19 4.57
57 INT80983 Regulation of Abcb1b 2 16 0.60 1.95 4.32
58 INT33951 Regulation of TXNRD1 1 18 0.51 6.97 4.02
59 INT50022 Positive_regulation of G2e3 1 10 0.42 0.47 3.72
60 INT2877 Localization of GUSB 1 9 0.80 0.81 3.63
61 INT6405 Gene_expression of Enpep 2 9 0.67 4.79 3.4
62 INT61952 Negative_regulation of Transcription of Nos2 2 17 0.54 5.1 3.34
63 INT53388 Negative_regulation of Cyp2c11 2 18 0.53 2.66 3.11
64 INT70563 Localization of ABCB1 3 14 0.78 2.03 3.09
65 INT120529 Positive_regulation of ABCC2 1 7 0.49 2.32 2.94
66 INT104182 Gene_expression of ABCC2 5 19 0.76 5.92 2.88
67 INT28934 Negative_regulation of Gene_expression of Cyp2c22 1 9 0.12 2.15 2.86
68 INT79867 Positive_regulation of SLC15A1 3 17 0.70 3.01 2.75
69 INT90299 Negative_regulation of Gene_expression of Abcb1a 1 4 0.43 0.54 2.65
70 INT20304 Transcription of Cyp2e1 2 11 0.70 2.5 2.57
71 INT60423 Positive_regulation of TPSG1 1 11 0.57 11.02 2.55
72 INT21255 Binding of Slco1c1 1 9 0.33 5.11 2.45
73 INT80391 Negative_regulation of Cyp2b2 2 4 0.54 0.12 2.36
74 INT84465 Localization of DPP4 1 8 0.75 7.28 2.29
75 INT36616 Positive_regulation of Binding of ALB 1 8 0.67 3 2.07
76 INT73359 Gene_expression of GLB1 1 8 0.75 3.18 1.92
77 INT45064 Protein_catabolism of TRIM13 3 6 0.86 0 1.8
78 INT40322 Binding of Pnp 1 12 0.38 11.13 1.78
79 INT59291 Positive_regulation of Ctnnbl1 1 6 0.37 0.38 1.63
80 INT31616 Protein_catabolism of DNM2 1 5 0.75 1.61 1.63
81 INT104185 Negative_regulation of ABCC2 3 7 0.57 0.64 1.5
82 INT1851 Regulation of OXA1L 1 7 0.40 0.59 1.42
83 INT54020 Regulation of Binding of OXA1L 2 4 0.51 0.27 1.37
84 INT104183 Positive_regulation of Gene_expression of ABCC2 4 7 0.68 1.16 1.17
85 INT135919 Binding of SLC5A8 5 1 0.47 0 1.12
86 INT19084 Negative_regulation of NRG1 1 5 0.42 4.9 0.96
87 INT104188 Protein_catabolism of ASAH1 1 2 0.36 1.11 0.89
88 INT25173 Localization of H2-M3 1 3 0.17 0.59 0.8
89 INT30397 Positive_regulation of DNM2 1 3 0.31 1.44 0.79
90 INT98177 Negative_regulation of Transcription of Cyp2e1 2 2 0.40 0.89 0.75
91 INT2221 Binding of Rbp4 2 6 0.48 1.54 0.71
92 INT50440 Negative_regulation of Pnp 1 5 0.36 2.14 0.66
93 INT125635 Negative_regulation of Cyp2c6 1 3 0.59 0.18 0.66
94 INT115823 Transcription of Cyp3a23/3a1 2 3 0.54 0.82 0.61
95 INT142419 Regulation of Sptan1 1 2 0.38 2.52 0.55
96 INT30104 Binding of Eh 1 1 0.02 0 0.55
97 INT19083 Positive_regulation of NRG1 2 3 0.20 0.65 0.48
98 INT35960 Binding of Zdhhc2 1 2 0.36 1.96 0.48
99 INT57109 Binding of MYBPC1 1 1 0.00 0 0.4
100 INT120525 Gene_expression of SLCO1B3 1 2 0.57 1.47 0.33
101 INT112287 Gene_expression of SLCO1B1 1 3 0.75 0.09 0.32
102 INT80980 Regulation of Regulation of Abcb1a 1 1 0.45 0 0.32
103 INT80982 Regulation of Regulation of Abcb1b 1 1 0.60 0 0.32
104 INT54255 Transcription of Cyp2c11 1 5 0.66 2.01 0.3
105 INT54256 Negative_regulation of Transcription of Cyp2c11 1 4 0.42 1.87 0.21
106 INT100606 Regulation of Gene_expression of Cyp2c22 1 3 0.05 0.36 0.18
107 INT120526 Positive_regulation of Gene_expression of SLCO1B3 1 2 0.34 0.65 0.18
108 INT138336 Gene_expression of CHRNA7 1 1 0.35 0 0.17
109 INT54099 Protein_catabolism of Trpm8 1 1 0.54 0.17 0.17
110 INT54093 Protein_catabolism of NRG1 2 1 0.26 0 0.16
111 INT91673 Transcription of Cyp3a2 1 5 0.71 0.41 0.09
112 INT115832 Negative_regulation of Transcription of Cyp3a23/3a1 2 1 0.34 0.51 0.09
113 INT54092 Regulation of Protein_catabolism of NRG1 1 1 0.13 0 0.09
114 INT54083 Protein_catabolism of Fgg 1 1 0.15 0 0.09
115 INT35961 Positive_regulation of Zdhhc2 1 1 0.49 0.1 0.09
116 INT54084 Regulation of Protein_catabolism of Fgg 1 1 0.07 0 0.09
117 INT135918 Gene_expression of SLC5A8 2 3 0.78 1.46 0.07
118 INT54094 Positive_regulation of Protein_catabolism of NRG1 1 1 0.14 0 0.07
119 INT106434 Protein_catabolism of OXA1L 1 3 0.54 0.46 0.04
120 INT86002 Binding of PBCA 2 3 0.11 0.75 0.03
121 INT66937 Binding of NR3C2 1 3 0.26 0.77 0
122 INT79863 Negative_regulation of RGD1563334 4 3 0.01 0 0
123 INT120527 Localization of ABCC2 2 3 0.78 1.03 0
124 INT125640 Regulation of Cyp3a2 1 3 0.45 0.09 0
125 INT79864 Positive_regulation of Protein_catabolism of TRIM13 2 2 0.31 0 0
126 INT104184 Negative_regulation of Negative_regulation of ABCB1 2 2 0.38 0 0
127 INT145647 Gene_expression of TPSB2 1 1 0.43 0 0
128 INT125634 Transcription of Cyp2b2 1 1 0.09 0 0
129 INT125639 Negative_regulation of Transcription of Cyp2c6 1 1 0.38 0 0
130 INT125632 Negative_regulation of Transcription of Cyp2b2 1 1 0.05 0 0
131 INT142820 Binding of Slc15a1 1 1 0.37 0 0
132 INT86003 Negative_regulation of PBCA 1 1 0.12 0 0
133 INT120528 Negative_regulation of Gene_expression of SLCO1B1 1 1 0.43 0 0
134 INT48019 Localization of CR1L 3 1 0.51 0 0
135 INT125637 Transcription of Cyp2c6 1 1 0.61 0 0
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