J:Pharmacol. Ther.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT78348 Binding of GALR1 and GAL 4 1 0.41 1.47 0.8
2 INT96833 Binding of WAS and Positive_regulation of Cnr1 1 1 0.02 0.69 0.39
3 INT96834 Binding of WAS and Positive_regulation of Cnr2 1 1 0.03 0.69 0.39
4 INT96836 WAS Positive_regulation of Cnr1 1 1 0.02 0.69 0.39
5 INT96835 WAS Positive_regulation of Cnr2 1 1 0.03 0.69 0.39
6 INT55252 Binding of CCK and RIPK2 1 1 0.40 0 0.2
7 INT122710 GUCA2A Positive_regulation of RTCA 1 1 0.03 0.16 0.05
8 INT122713 Guca2b Positive_regulation of RTCA 1 1 0.03 0.16 0.05

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT18357 Gene_expression of TRPV1 1 825 0.78 307.11 382.81
2 INT5660 Binding of Oprd1 3 477 0.48 71.86 342.06
3 INT2649 Regulation of Calca 2 433 0.62 146.05 330.95
4 INT4941 Positive_regulation of Oprd1 2 345 0.70 74.26 304.41
5 INT11624 Gene_expression of OPRM1 1 445 0.78 72.36 294.36
6 INT9381 Positive_regulation of TRPV1 1 523 0.70 187.4 276.05
7 INT5501 Regulation of Oprd1 1 283 0.62 55.1 249.9
8 INT626 Localization of CALCA 3 289 0.81 125.39 221.15
9 INT11313 Positive_regulation of Il6 1 526 0.70 331.27 201.59
10 INT10194 Positive_regulation of IL6 1 702 0.70 600.62 183.38
11 INT2867 Gene_expression of CALCA 1 247 0.78 78.78 138.47
12 INT48767 Negative_regulation of NOS1 1 312 0.59 154.25 90.32
13 INT86521 Gene_expression of Lpar1 1 167 0.78 154.61 80.35
14 INT87686 Positive_regulation of Gene_expression of Trpv1 1 101 0.70 72.41 69.15
15 INT7344 Gene_expression of TAC1 3 132 0.75 35.48 68.26
16 INT7134 Localization of KNG1 1 127 0.79 65.73 67.97
17 INT654 Localization of REN 1 250 0.81 75.12 47.86
18 INT48718 Positive_regulation of PRKCA 1 109 0.69 36.16 46.49
19 INT11406 Positive_regulation of Localization of CALCA 2 49 0.70 20.64 42.8
20 INT43507 Gene_expression of Gabbr1 1 79 0.78 28.53 38.22
21 INT64436 Gene_expression of P2rx1 1 93 0.78 32.69 36.12
22 INT8837 Positive_regulation of TAC1 1 59 0.67 21.94 35.97
23 INT49519 Gene_expression of P2rx7 1 84 0.76 36.88 34.69
24 INT17381 Gene_expression of Tbxa2r 1 146 0.78 65.01 34.15
25 INT4868 Gene_expression of GAL 4 75 0.78 22.23 29.02
26 INT23463 Positive_regulation of Gene_expression of CALCA 1 47 0.70 18.14 28.76
27 INT2408 Regulation of CCK 1 37 0.61 10.01 26.66
28 INT8779 Binding of TAC1 1 50 0.47 11.19 25.57
29 INT67585 Gene_expression of UGT2B7 1 52 0.78 2.33 24.13
30 INT8775 Binding of IGHE 1 167 0.48 102.61 23.54
31 INT94335 Positive_regulation of CXCL10 1 71 0.58 50.69 23
32 INT39914 Negative_regulation of Cyp1a2 1 44 0.58 10.04 22
33 INT8358 Negative_regulation of Localization of CALCA 1 25 0.59 11.79 21.51
34 INT1756 Negative_regulation of DNAH8 2 105 0.59 42.73 20.24
35 INT23787 Positive_regulation of P2rx7 1 36 0.68 23.54 19.45
36 INT79955 Localization of Cnr1 1 26 0.81 8.44 19.06
37 INT31905 Positive_regulation of Binding of Oprd1 1 21 0.66 3.31 18.44
38 INT27670 Negative_regulation of Ace 1 122 0.57 79.21 18.08
39 INT9358 Positive_regulation of HTR1B 1 26 0.67 11 17.51
40 INT69652 Regulation of P2rx3 3 26 0.61 17.17 15.4
41 INT95 Positive_regulation of Adrb1 1 34 0.62 11.95 14.41
42 INT64563 Gene_expression of UGT1A1 1 27 0.75 3.31 13.43
43 INT88365 Regulation of Faah 1 18 0.45 6.63 12.54
44 INT98329 Gene_expression of P2RX4 2 23 0.75 13.13 10.25
45 INT53547 Binding of TACR1 1 22 0.48 5.03 9.48
46 INT6019 Positive_regulation of NEUROD1 1 37 0.67 17.3 8.89
47 INT78578 Localization of P2rx3 4 21 0.78 9.55 8.86
48 INT34268 Binding of WAS 1 14 0.47 4.41 8.67
49 INT13085 Positive_regulation of ACE 1 50 0.70 44.2 8.31
50 INT62725 Regulation of GRIN2D 1 6 0.45 2.98 5.68
51 INT58750 Binding of GAL 1 16 0.47 5.48 4.92
52 INT130203 Gene_expression of P2ry4 1 14 0.50 8.79 4.82
53 INT8786 Negative_regulation of ALDH7A1 1 27 0.52 12.81 4.76
54 INT50657 Positive_regulation of HTR2B 1 8 0.67 3.95 4.71
55 INT29327 Positive_regulation of Ace 1 13 0.67 8.79 4.33
56 INT112040 Localization of P2RX2 3 6 0.73 4.69 4.3
57 INT95171 Binding of P2rx1 1 12 0.36 4.69 3.92
58 INT16723 Regulation of GBE1 1 16 0.11 4.3 3.7
59 INT128679 Negative_regulation of Bdkrb2 1 7 0.35 6.78 3.54
60 INT88549 Regulation of SLC35A2 1 8 0.60 0.7 3.52
61 INT11490 Binding of KCNMA1 1 13 0.37 3.61 3.32
62 INT129441 Regulation of Gene_expression of P2rx7 1 8 0.24 4.29 3.32
63 INT60479 Gene_expression of SLC35A2 5 17 0.75 0.97 3.26
64 INT104671 Binding of Faah 1 7 0.37 1.75 3.25
65 INT130202 Negative_regulation of Gene_expression of P2ry4 2 3 0.15 3.89 3.14
66 INT130906 Regulation of P2RX2 3 1 0.26 2.41 2.57
67 INT101055 Regulation of GRIN2B 2 4 0.61 1.39 2.5
68 INT106740 Regulation of Ugcg 1 14 0.22 11.5 1.88
69 INT104672 Negative_regulation of Neu3 2 4 0.14 4.67 1.82
70 INT130204 Positive_regulation of Gene_expression of P2ry4 1 2 0.00 2.73 1.79
71 INT107379 Localization of GRIN2B 1 2 0.73 0.86 1.48
72 INT4264 Binding of SEMA6A 1 2 0.36 0 1.34
73 INT84228 Gene_expression of UGT1A10 1 7 0.77 0.4 1.23
74 INT120287 Regulation of Abcc2 1 2 0.24 0.81 1.06
75 INT17636 Binding of Cyp1a1 1 3 0.31 0.31 1
76 INT70355 Localization of GRIN2D 1 1 0.76 0.07 0.94
77 INT137082 Regulation of ABCC2 1 2 0.16 1.11 0.85
78 INT69749 Binding of Tacr3 1 3 0.06 2.2 0.81
79 INT76946 Gene_expression of UGT1A8 1 12 0.78 0 0.78
80 INT43946 Gene_expression of UGT2A2 1 3 0.06 1.08 0.61
81 INT17637 Positive_regulation of Cyp1a1 1 2 0.01 0.31 0.37
82 INT109476 Gene_expression of UGT1A7 1 5 0.78 0.9 0.32
83 INT107380 Regulation of Localization of GRIN2D 1 1 0.30 0.07 0.27
84 INT48022 Protein_catabolism of BCHE 1 1 0.87 0 0.24
85 INT145003 Gene_expression of GALP 2 3 0.67 0.58 0.23
86 INT128580 Negative_regulation of Positive_regulation of CXCL10 1 1 0.02 0.57 0.22
87 INT69750 Regulation of Positive_regulation of TAC1 1 1 0.16 0.28 0.16
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