J:Pharmacol. Ther.

This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT78348	Binding of GALR1 and GAL	4	1	0.41	1.47	0.8
2	INT96833	Binding of WAS and Positive_regulation of Cnr1	1	1	0.02	0.69	0.39
3	INT96834	Binding of WAS and Positive_regulation of Cnr2	1	1	0.03	0.69	0.39
4	INT96836	WAS Positive_regulation of Cnr1	1	1	0.02	0.69	0.39
5	INT96835	WAS Positive_regulation of Cnr2	1	1	0.03	0.69	0.39
6	INT55252	Binding of CCK and RIPK2	1	1	0.40	0	0.2
7	INT122710	GUCA2A Positive_regulation of RTCA	1	1	0.03	0.16	0.05
8	INT122713	Guca2b Positive_regulation of RTCA	1	1	0.03	0.16	0.05

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT18357	Gene_expression of TRPV1	1	825	0.78	307.11	382.81
2	INT5660	Binding of Oprd1	3	477	0.48	71.86	342.06
3	INT2649	Regulation of Calca	2	433	0.62	146.05	330.95
4	INT4941	Positive_regulation of Oprd1	2	345	0.70	74.26	304.41
5	INT11624	Gene_expression of OPRM1	1	445	0.78	72.36	294.36
6	INT9381	Positive_regulation of TRPV1	1	523	0.70	187.4	276.05
7	INT5501	Regulation of Oprd1	1	283	0.62	55.1	249.9
8	INT626	Localization of CALCA	3	289	0.81	125.39	221.15
9	INT11313	Positive_regulation of Il6	1	526	0.70	331.27	201.59
10	INT10194	Positive_regulation of IL6	1	702	0.70	600.62	183.38
11	INT2867	Gene_expression of CALCA	1	247	0.78	78.78	138.47
12	INT48767	Negative_regulation of NOS1	1	312	0.59	154.25	90.32
13	INT86521	Gene_expression of Lpar1	1	167	0.78	154.61	80.35
14	INT87686	Positive_regulation of Gene_expression of Trpv1	1	101	0.70	72.41	69.15
15	INT7344	Gene_expression of TAC1	3	132	0.75	35.48	68.26
16	INT7134	Localization of KNG1	1	127	0.79	65.73	67.97
17	INT654	Localization of REN	1	250	0.81	75.12	47.86
18	INT48718	Positive_regulation of PRKCA	1	109	0.69	36.16	46.49
19	INT11406	Positive_regulation of Localization of CALCA	2	49	0.70	20.64	42.8
20	INT43507	Gene_expression of Gabbr1	1	79	0.78	28.53	38.22
21	INT64436	Gene_expression of P2rx1	1	93	0.78	32.69	36.12
22	INT8837	Positive_regulation of TAC1	1	59	0.67	21.94	35.97
23	INT49519	Gene_expression of P2rx7	1	84	0.76	36.88	34.69
24	INT17381	Gene_expression of Tbxa2r	1	146	0.78	65.01	34.15
25	INT4868	Gene_expression of GAL	4	75	0.78	22.23	29.02
26	INT23463	Positive_regulation of Gene_expression of CALCA	1	47	0.70	18.14	28.76
27	INT2408	Regulation of CCK	1	37	0.61	10.01	26.66
28	INT8779	Binding of TAC1	1	50	0.47	11.19	25.57
29	INT67585	Gene_expression of UGT2B7	1	52	0.78	2.33	24.13
30	INT8775	Binding of IGHE	1	167	0.48	102.61	23.54
31	INT94335	Positive_regulation of CXCL10	1	71	0.58	50.69	23
32	INT39914	Negative_regulation of Cyp1a2	1	44	0.58	10.04	22
33	INT8358	Negative_regulation of Localization of CALCA	1	25	0.59	11.79	21.51
34	INT1756	Negative_regulation of DNAH8	2	105	0.59	42.73	20.24
35	INT23787	Positive_regulation of P2rx7	1	36	0.68	23.54	19.45
36	INT79955	Localization of Cnr1	1	26	0.81	8.44	19.06
37	INT31905	Positive_regulation of Binding of Oprd1	1	21	0.66	3.31	18.44
38	INT27670	Negative_regulation of Ace	1	122	0.57	79.21	18.08
39	INT9358	Positive_regulation of HTR1B	1	26	0.67	11	17.51
40	INT69652	Regulation of P2rx3	3	26	0.61	17.17	15.4
41	INT95	Positive_regulation of Adrb1	1	34	0.62	11.95	14.41
42	INT64563	Gene_expression of UGT1A1	1	27	0.75	3.31	13.43
43	INT88365	Regulation of Faah	1	18	0.45	6.63	12.54
44	INT98329	Gene_expression of P2RX4	2	23	0.75	13.13	10.25
45	INT53547	Binding of TACR1	1	22	0.48	5.03	9.48
46	INT6019	Positive_regulation of NEUROD1	1	37	0.67	17.3	8.89
47	INT78578	Localization of P2rx3	4	21	0.78	9.55	8.86
48	INT34268	Binding of WAS	1	14	0.47	4.41	8.67
49	INT13085	Positive_regulation of ACE	1	50	0.70	44.2	8.31
50	INT62725	Regulation of GRIN2D	1	6	0.45	2.98	5.68
51	INT58750	Binding of GAL	1	16	0.47	5.48	4.92
52	INT130203	Gene_expression of P2ry4	1	14	0.50	8.79	4.82
53	INT8786	Negative_regulation of ALDH7A1	1	27	0.52	12.81	4.76
54	INT50657	Positive_regulation of HTR2B	1	8	0.67	3.95	4.71
55	INT29327	Positive_regulation of Ace	1	13	0.67	8.79	4.33
56	INT112040	Localization of P2RX2	3	6	0.73	4.69	4.3
57	INT95171	Binding of P2rx1	1	12	0.36	4.69	3.92
58	INT16723	Regulation of GBE1	1	16	0.11	4.3	3.7
59	INT128679	Negative_regulation of Bdkrb2	1	7	0.35	6.78	3.54
60	INT88549	Regulation of SLC35A2	1	8	0.60	0.7	3.52
61	INT11490	Binding of KCNMA1	1	13	0.37	3.61	3.32
62	INT129441	Regulation of Gene_expression of P2rx7	1	8	0.24	4.29	3.32
63	INT60479	Gene_expression of SLC35A2	5	17	0.75	0.97	3.26
64	INT104671	Binding of Faah	1	7	0.37	1.75	3.25
65	INT130202	Negative_regulation of Gene_expression of P2ry4	2	3	0.15	3.89	3.14
66	INT130906	Regulation of P2RX2	3	1	0.26	2.41	2.57
67	INT101055	Regulation of GRIN2B	2	4	0.61	1.39	2.5
68	INT106740	Regulation of Ugcg	1	14	0.22	11.5	1.88
69	INT104672	Negative_regulation of Neu3	2	4	0.14	4.67	1.82
70	INT130204	Positive_regulation of Gene_expression of P2ry4	1	2	0.00	2.73	1.79
71	INT107379	Localization of GRIN2B	1	2	0.73	0.86	1.48
72	INT4264	Binding of SEMA6A	1	2	0.36	0	1.34
73	INT84228	Gene_expression of UGT1A10	1	7	0.77	0.4	1.23
74	INT120287	Regulation of Abcc2	1	2	0.24	0.81	1.06
75	INT17636	Binding of Cyp1a1	1	3	0.31	0.31	1
76	INT70355	Localization of GRIN2D	1	1	0.76	0.07	0.94
77	INT137082	Regulation of ABCC2	1	2	0.16	1.11	0.85
78	INT69749	Binding of Tacr3	1	3	0.06	2.2	0.81
79	INT76946	Gene_expression of UGT1A8	1	12	0.78	0	0.78
80	INT43946	Gene_expression of UGT2A2	1	3	0.06	1.08	0.61
81	INT17637	Positive_regulation of Cyp1a1	1	2	0.01	0.31	0.37
82	INT109476	Gene_expression of UGT1A7	1	5	0.78	0.9	0.32
83	INT107380	Regulation of Localization of GRIN2D	1	1	0.30	0.07	0.27
84	INT48022	Protein_catabolism of BCHE	1	1	0.87	0	0.24
85	INT145003	Gene_expression of GALP	2	3	0.67	0.58	0.23
86	INT128580	Negative_regulation of Positive_regulation of CXCL10	1	1	0.02	0.57	0.22
87	INT69750	Regulation of Positive_regulation of TAC1	1	1	0.16	0.28	0.16