J:Physiol. Behav.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT28925 Cpe Regulation of Sh2b3 1 1 0.04 0.14 0.55
2 INT148629 Binding of Cat and Casp3 1 1 0.08 0.09 0.26
3 INT124036 Binding of App and Dnahc8 1 1 0.03 0.14 0.09

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT158 Localization of Prl 4 2431 0.81 378.96 952.2
2 INT6483 Gene_expression of TNF 1 3152 0.78 2515.62 929.82
3 INT1912 Gene_expression of Calca 1 1152 0.78 453.25 739.84
4 INT292 Localization of Penk 2 876 0.81 88.44 669.14
5 INT58061 Gene_expression of Trpv1 5 1117 0.78 451.54 637.59
6 INT728 Positive_regulation of Penk 1 1068 0.70 186.9 636.87
7 INT797 Regulation of Penk 2 812 0.62 111.13 542.24
8 INT155 Positive_regulation of Prl 8 1233 0.70 317.93 457.82
9 INT1045 Localization of LH 1 1211 0.81 87.04 456.25
10 INT467 Gene_expression of POMC 1 1048 0.78 332.8 394.16
11 INT1395 Negative_regulation of Penk 5 537 0.59 87.33 389.81
12 INT157 Positive_regulation of Localization of Prl 1 790 0.70 104.54 374.78
13 INT287 Localization of Cck 1 518 0.81 86.84 364.04
14 INT439 Localization of Gnrh1 2 976 0.81 100.96 363.25
15 INT720 Positive_regulation of POMC 1 807 0.70 237.37 353.83
16 INT5660 Binding of Oprd1 1 477 0.48 71.86 342.06
17 INT2649 Regulation of Calca 4 433 0.62 146.05 330.95
18 INT5059 Positive_regulation of TNF 1 1050 0.70 896.51 322.81
19 INT162 Regulation of Prl 8 794 0.62 165.01 322.24
20 INT5979 Gene_expression of Oprd1 1 428 0.78 75.64 320.32
21 INT477 Localization of Avp 2 813 0.81 131.58 300.4
22 INT886 Gene_expression of Pomc 7 676 0.78 129.87 295.98
23 INT3579 Localization of Oxt 5 555 0.81 43.35 292.44
24 INT1396 Binding of Penk 2 355 0.48 22.79 269.65
25 INT3948 Regulation of Cck 1 291 0.62 58.07 255.88
26 INT1005 Localization of Sst 2 385 0.81 26.31 244.56
27 INT738 Regulation of POMC 2 459 0.62 111.19 243.74
28 INT1562 Localization of Crh 1 499 0.81 126.74 236.68
29 INT1665 Positive_regulation of Pag1 1 270 0.68 186.63 229.87
30 INT6406 Binding of Oprm1 1 280 0.48 40.54 226.26
31 INT1212 Binding of Oprl1 1 312 0.48 28.6 225.15
32 INT1308 Localization of Pomc 2 457 0.81 66.83 217.5
33 INT6293 Gene_expression of Oprm1 1 312 0.78 48.73 215.61
34 INT767 Localization of Gnrhr 3 565 0.80 106.68 214.57
35 INT2651 Positive_regulation of Pomc 12 403 0.70 95.72 206.24
36 INT11313 Positive_regulation of Il6 5 526 0.70 331.27 201.59
37 INT156 Negative_regulation of Prl 8 542 0.59 131.97 192.24
38 INT528 Gene_expression of Prl 2 693 0.78 217.18 192.2
39 INT1652 Regulation of Pomc 5 387 0.62 61.01 186.51
40 INT12602 Negative_regulation of Oprm1 1 190 0.59 36.11 177.85
41 INT943 Negative_regulation of Cck 3 205 0.59 38.42 174.78
42 INT5930 Positive_regulation of Oprm1 1 221 0.70 31.19 172.93
43 INT159 Negative_regulation of Localization of Prl 1 416 0.59 55.34 171.8
44 INT867 Gene_expression of IFNA1 1 930 0.78 594.85 168.03
45 INT1114 Localization of Ins1 5 748 0.80 192.95 165.48
46 INT5513 Negative_regulation of Pomc 3 295 0.59 60.9 158.63
47 INT6042 Binding of Oprm1 1 248 0.48 31.77 154.34
48 INT2910 Regulation of Abat 1 169 0.62 36.95 153.53
49 INT1044 Negative_regulation of Localization of LH 1 358 0.59 25.95 151.31
50 INT6108 Gene_expression of Npy 3 292 0.78 110.65 148.21
51 INT13353 Positive_regulation of Tnf 5 332 0.70 248.75 148.1
52 INT3300 Positive_regulation of Gene_expression of Calca 1 179 0.70 77.76 144.2
53 INT1414 Regulation of Oprl1 1 169 0.62 32.05 139.99
54 INT1047 Negative_regulation of LH 4 314 0.59 53.71 135.89
55 INT5497 Positive_regulation of Crh 3 299 0.70 125.54 131.14
56 INT65600 Positive_regulation of Casp3 1 376 0.70 198.44 128.03
57 INT1614 Gene_expression of Oprl1 1 164 0.78 31.43 127.74
58 INT416 Regulation of LH 2 253 0.62 31.48 125.55
59 INT2106 Regulation of Localization of LH 1 279 0.62 22.37 122.77
60 INT14151 Gene_expression of Casp3 2 311 0.78 140.26 120.68
61 INT10272 Gene_expression of Il1b 1 194 0.78 121.02 103.03
62 INT1351 Gene_expression of Pag1 2 131 0.57 89.48 98.76
63 INT18755 Positive_regulation of Rvm 1 79 0.60 60 92.93
64 INT203 Positive_regulation of Pomc 1 257 0.70 90.56 92.84
65 INT18032 Positive_regulation of Oprk1 1 108 0.70 30.78 89.7
66 INT6214 Negative_regulation of Adarb1 4 123 0.50 26.39 89.57
67 INT7885 Positive_regulation of Localization of Oxt 1 160 0.70 14.36 87.7
68 INT1472 Positive_regulation of Ins1 1 349 0.69 146.2 86.36
69 INT5610 Positive_regulation of Insr 3 140 0.69 37.26 86.24
70 INT8650 Gene_expression of Gal 5 152 0.78 61.97 81.72
71 INT7528 Regulation of OPRM1 2 100 0.62 20.63 80.57
72 INT2289 Gene_expression of PENK 1 203 0.78 55.62 79.49
73 INT2893 Localization of Oxt 1 219 0.80 28.96 79.43
74 INT2155 Negative_regulation of Sst 1 111 0.59 16.58 77.74
75 INT4358 Positive_regulation of Localization of Avp 4 195 0.70 30.79 77.58
76 INT10274 Positive_regulation of Il1b 2 123 0.70 79.76 73.56
77 INT11380 Negative_regulation of IL1B 1 215 0.59 125.62 72.35
78 INT5128 Positive_regulation of Lhb 1 232 0.69 44.23 71.26
79 INT2055 Regulation of Gnrh1 1 185 0.62 23.65 71.26
80 INT1988 Positive_regulation of Localization of Ins1 2 254 0.69 59.25 68.37
81 INT462 Regulation of Pomc 1 157 0.62 41.67 67.27
82 INT1046 Gene_expression of LH 1 180 0.77 29.75 66.87
83 INT7468 Negative_regulation of Localization of Oxt 1 109 0.59 9.46 66.79
84 INT6176 Positive_regulation of Htr1a 1 117 0.67 28.23 66.17
85 INT1437 Negative_regulation of Pomc 1 132 0.59 35.22 60.97
86 INT1307 Positive_regulation of Localization of Pomc 1 120 0.70 24.58 58.48
87 INT48901 Negative_regulation of IL6 1 186 0.57 136.33 57.87
88 INT1463 Binding of Pomc 1 129 0.48 15.89 56.27
89 INT1200 Negative_regulation of Ins1 1 274 0.58 155.17 56.14
90 INT314 Positive_regulation of Ren 1 212 0.70 66.68 55.56
91 INT251 Regulation of INS 1 398 0.62 232.47 55.04
92 INT5034 Negative_regulation of Insr 7 100 0.55 28.08 54.5
93 INT1487 Regulation of Cpe 1 68 0.62 10.24 52.91
94 INT937 Positive_regulation of Oxt 1 195 0.70 37.82 49.3
95 INT4345 Gene_expression of Gtf3a 1 157 0.67 80.75 48.47
96 INT1977 Negative_regulation of Positive_regulation of Prl 1 98 0.59 17.06 47.88
97 INT1715 Positive_regulation of Nrm 1 51 0.70 24 47.53
98 INT5337 Negative_regulation of Npy 2 87 0.59 19.6 46.75
99 INT847 Regulation of Lhb 1 131 0.61 22.08 46.54
100 INT66331 Gene_expression of Cacna1a 1 101 0.78 49.58 46.32
101 INT619 Positive_regulation of Positive_regulation of Prl 4 116 0.70 22.69 45.06
102 INT2275 Negative_regulation of Localization of Ins1 3 183 0.59 51.02 44.94
103 INT49552 Negative_regulation of Positive_regulation of Casp3 2 76 0.55 36.04 44.78
104 INT27493 Negative_regulation of Casp3 1 114 0.56 56.89 44.63
105 INT26698 Positive_regulation of Cacna1a 2 37 0.67 26.33 39.1
106 INT2782 Regulation of Gene_expression of Pomc 2 75 0.62 15.04 38.97
107 INT2531 Positive_regulation of Cebpz 1 166 0.00 43.08 38.86
108 INT5039 Positive_regulation of Gal 2 67 0.68 27.97 37.36
109 INT1361 Negative_regulation of Gnrhr 1 118 0.58 57.77 35.54
110 INT8747 Positive_regulation of Ins1 1 221 0.69 154.28 35.15
111 INT6177 Binding of Htr1a 1 65 0.47 17.65 30.59
112 INT8691 Localization of Insr 3 85 0.80 9.27 30.32
113 INT1473 Localization of Gcg 6 95 0.80 17.35 30.31
114 INT1158 Regulation of Agt 1 106 0.61 29.4 30.29
115 INT894 Binding of Avp 3 84 0.48 29.16 29.63
116 INT12319 Positive_regulation of Cort 8 52 0.61 22.55 29.35
117 INT65597 Negative_regulation of Casp3 1 69 0.59 39.19 29.32
118 INT5300 Regulation of Insr 1 54 0.60 11.33 29.26
119 INT66868 Positive_regulation of Ceacam3 1 40 0.69 26.61 28.9
120 INT16879 Binding of Crh 1 72 0.48 21.65 28.43
121 INT52722 Localization of RETNLB 1 54 0.38 48.63 27.98
122 INT6174 Regulation of Gene_expression of POMC 1 49 0.61 9.75 27.69
123 INT3559 Negative_regulation of Localization of Gnrhr 1 73 0.58 18.89 26.41
124 INT5948 Regulation of Il1b 1 44 0.60 22.8 25.4
125 INT8122 Regulation of Htr1a 1 39 0.60 8.96 24.89
126 INT10349 Negative_regulation of Il1b 1 48 0.58 25.53 24.24
127 INT9355 Binding of pcp 1 81 0.46 10.41 24.22
128 INT8380 Positive_regulation of Gene_expression of Npy 2 49 0.70 19.62 24.13
129 INT13145 Positive_regulation of Car1 2 60 0.70 16.32 23.23
130 INT16721 Negative_regulation of Cat 1 56 0.59 44.44 22.84
131 INT11077 Positive_regulation of Htr3a 1 63 0.67 15.61 22.7
132 INT7573 Positive_regulation of Nr3c2 1 38 0.67 20 21.84
133 INT19199 Negative_regulation of Rvm 1 16 0.37 10.07 21.73
134 INT5040 Regulation of Gal 1 42 0.60 12.72 21.18
135 INT2894 Negative_regulation of Localization of Oxt 1 43 0.58 4.59 20.85
136 INT1512 Binding of Prl 2 73 0.48 26.22 20.63
137 INT5096 Positive_regulation of Gtf3a 1 79 0.60 42.26 20.62
138 INT10520 Regulation of Rvm 1 20 0.24 10.15 20.52
139 INT7000 Positive_regulation of Htr2a 1 42 0.67 9.48 18.7
140 INT5533 Binding of Oxt 1 43 0.48 8.69 18.35
141 INT7056 Positive_regulation of Gene_expression of PENK 1 35 0.70 14.31 18.21
142 INT58495 Positive_regulation of Positive_regulation of Oprm1 1 22 0.49 2.44 17.66
143 INT9780 Regulation of Penk 1 30 0.60 6.78 17.19
144 INT51576 Positive_regulation of Cxcl1 1 42 0.69 20.12 16.41
145 INT8530 Transcription of Penk 2 48 0.70 11.67 16.34
146 INT50932 Positive_regulation of Positive_regulation of Il6 2 36 0.69 24.9 16.12
147 INT9751 Localization of Crhr1 1 26 0.78 10.47 15.69
148 INT15643 Positive_regulation of Positive_regulation of Pomc 3 30 0.65 4.59 15.34
149 INT75908 Regulation of LEP 1 77 0.60 60.16 15.19
150 INT663 Negative_regulation of Adrb3 1 55 0.59 15.95 14.68
151 INT8986 Positive_regulation of Gene_expression of Gal 2 24 0.67 10.96 14.09
152 INT64048 Positive_regulation of Positive_regulation of Tnf 2 32 0.70 21.24 13.74
153 INT12321 Binding of Nr3c2 1 19 0.46 5.44 13.46
154 INT20066 Gene_expression of Mdk 1 38 0.76 21.41 13.4
155 INT6575 Positive_regulation of Localization of Gcg 3 33 0.69 3.48 13.31
156 INT1148 Positive_regulation of ecs 1 38 0.48 25.27 13.1
157 INT64445 Gene_expression of Mc4r 1 17 0.78 5.06 12.91
158 INT73641 Regulation of Lep 1 45 0.62 26.2 12.59
159 INT56883 Positive_regulation of Dll1 1 8 0.49 3.49 12.25
160 INT117502 Positive_regulation of Adipoq 1 70 0.63 40.43 12.03
161 INT12315 Gene_expression of Nr3c2 2 37 0.75 19.28 11.97
162 INT5515 Negative_regulation of Positive_regulation of Pomc 1 25 0.58 8.73 11.88
163 INT3699 Gene_expression of H2-Ab1 1 24 0.74 12.06 11.82
164 INT82079 Positive_regulation of Lep 1 79 0.70 40 11.07
165 INT3546 Binding of Oxt 1 54 0.48 9.75 10.81
166 INT7577 Regulation of Nr3c2 2 16 0.56 7.7 10.1
167 INT1378 Negative_regulation of Regulation of Prl 1 27 0.43 9.16 9.9
168 INT120509 Gene_expression of Cat 1 65 0.77 50.9 9.75
169 INT2059 Positive_regulation of Negative_regulation of Prl 1 24 0.70 5.7 9.37
170 INT33220 Negative_regulation of ras 1 110 0.58 70.21 9.19
171 INT56884 Gene_expression of Dll1 1 9 0.48 1.15 8.98
172 INT20835 Negative_regulation of Negative_regulation of Oprm1 1 10 0.43 0.56 8.96
173 INT15184 Negative_regulation of Nt5e 1 10 0.57 0.99 8.95
174 INT18391 Positive_regulation of GYPA 1 41 0.40 16.47 8.69
175 INT8903 Gene_expression of IFNA2 2 58 0.71 38.23 8.68
176 INT82082 Localization of Lep 1 63 0.81 26.41 8.56
177 INT2512 Negative_regulation of Cp 2 27 0.51 10.15 8.37
178 INT54368 Positive_regulation of VTA1 1 13 0.59 3.81 8.13
179 INT5498 Positive_regulation of Positive_regulation of Crh 1 19 0.70 9.82 7.97
180 INT7588 Regulation of NPY 1 13 0.44 6.97 7.97
181 INT21685 Gene_expression of ras 1 115 0.66 85.6 7.76
182 INT7570 Transcription of Crhr1 1 7 0.66 6.6 7.6
183 INT2587 Regulation of Localization of Gcg 3 22 0.60 1.73 7.59
184 INT81378 Negative_regulation of Dpp4 1 18 0.59 7.87 7.42
185 INT3659 Negative_regulation of Gcg 1 26 0.51 10.08 7.39
186 INT36960 Gene_expression of vs 2 33 0.43 20.77 6.97
187 INT5864 Localization of IL36RN 1 19 0.44 14.5 6.87
188 INT6758 Positive_regulation of Synm 2 12 0.43 2.57 6.83
189 INT12314 Negative_regulation of Nr3c2 4 16 0.56 14.82 6.72
190 INT115391 Gene_expression of Cort 1 18 0.59 9.43 6.53
191 INT29020 Positive_regulation of pcp 1 18 0.45 3.5 6.39
192 INT7842 Gene_expression of Adra1a 1 14 0.67 1.99 6.39
193 INT12316 Negative_regulation of Cort 1 10 0.38 5.89 6.08
194 INT8529 Regulation of Transcription of Penk 1 8 0.39 1.26 5.89
195 INT36921 Regulation of Mdk 1 14 0.26 6.49 5.8
196 INT101482 Negative_regulation of Lep 1 53 0.54 33.59 5.65
197 INT4034 Negative_regulation of Gip 1 16 0.53 6.46 5.65
198 INT6276 Negative_regulation of Positive_regulation of Pomc 1 12 0.57 3.65 5.49
199 INT77252 Gene_expression of Nr3c1 1 17 0.67 9.71 5.38
200 INT101556 Regulation of Nt5e 2 5 0.40 2.81 5.2
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