J:Proc. Natl. Acad. Sci. U.S.A.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT168715 Mapk8 Negative_regulation of Oprk1 1 1 0.18 0.26 1.75
2 INT168717 Mapk8 Positive_regulation of Mapk8 Negative_regulation of Oprk1 1 1 0.19 0.26 1.75
3 INT168716 Mapk8 Negative_regulation of Insrr 1 1 0.01 0.25 1.75
4 INT168791 Positive_regulation of Binding of AGFG1 and IVNS1ABP 1 1 0.01 0.39 0.26
5 INT168792 Negative_regulation of Binding of AGFG1 and IVNS1ABP 1 1 0.01 0.39 0.26
6 INT168790 Binding of AGFG1 and IVNS1ABP 1 1 0.01 0.39 0.26

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5540 Positive_regulation of Oprm1 2 344 0.70 76.77 319.71
2 INT22548 Positive_regulation of Casp3 1 483 0.70 258.78 213.07
3 INT12602 Negative_regulation of Oprm1 3 190 0.59 36.11 177.85
4 INT6437 Binding of YY1 1 154 0.47 26.3 90.46
5 INT18032 Positive_regulation of Oprk1 1 108 0.70 30.78 89.7
6 INT56291 Gene_expression of Ros1 2 503 0.63 274.12 81.5
7 INT102020 Gene_expression of Creb1 2 190 0.78 57.31 59.77
8 INT82055 Positive_regulation of Creb1 2 176 0.70 60.2 58.39
9 INT12471 Regulation of Insrr 1 52 0.35 17.8 48.31
10 INT108726 Binding of Mors1 1 38 0.33 7.08 43.62
11 INT71995 Binding of Crygs 3 54 0.11 10.03 39.31
12 INT96913 Positive_regulation of Mapk8 2 179 0.69 130.44 32.2
13 INT102021 Positive_regulation of Gene_expression of Creb1 2 66 0.70 24.04 23.28
14 INT62577 Negative_regulation of Creb1 1 55 0.59 19.68 18.1
15 INT3364 Binding of SGCG 1 87 0.47 31.93 17.24
16 INT109316 Negative_regulation of Mapk8 2 72 0.59 50.59 17.24
17 INT102023 Regulation of Creb1 1 51 0.62 16.29 16.71
18 INT107248 Negative_regulation of Gene_expression of Creb1 2 26 0.58 9.24 13.41
19 INT67653 Gene_expression of Om 1 46 0.36 15.28 13.32
20 INT158863 Negative_regulation of Ros1 1 84 0.35 40.3 10.14
21 INT116428 Gene_expression of Cybb 3 68 0.76 35.81 7.07
22 INT516 Negative_regulation of Mif 1 13 0.59 6.69 6.08
23 INT99438 Positive_regulation of Atf6b 1 12 0.49 4.28 5.97
24 INT83442 Negative_regulation of MIF 1 18 0.57 9.51 5.12
25 INT108919 Positive_regulation of Mapk9 1 9 0.34 3.55 4.74
26 INT163290 Binding of MIF 2 9 0.31 7.57 2.8
27 INT3394 Negative_regulation of HPP1 1 5 0.42 1.14 2.16
28 INT169533 Positive_regulation of Gene_expression of Cybb 1 16 0.68 8.62 2.14
29 INT109313 Binding of Mapk8 1 6 0.48 1.78 1.98
30 INT169720 Positive_regulation of Gene_expression of Om 1 3 0.04 1.51 1.69
31 INT168714 Negative_regulation of Binding of Mapk8 1 1 0.36 0.18 1.62
32 INT169776 Gene_expression of Opn4 1 52 0.77 8.75 1.38
33 INT42318 Negative_regulation of Hpd 1 2 0.31 0.57 1.24
34 INT169542 Negative_regulation of Lts1 1 5 0.12 2.74 1.23
35 INT169721 Negative_regulation of Negative_regulation of Creb1 1 1 0.43 0.09 1.22
36 INT169722 Negative_regulation of Gene_expression of Om 1 2 0.03 0.47 1.21
37 INT169779 Positive_regulation of Sdhb 3 4 0.67 1.2 0.64
38 INT169778 Positive_regulation of Opn4 1 8 0.68 1.63 0.63
39 INT169780 Gene_expression of Sdhb 1 2 0.65 0.69 0.54
40 INT64965 Binding of AGFG1 1 8 0.10 3.53 0.45
41 INT169777 Positive_regulation of Positive_regulation of Sdhb 2 1 0.58 0.24 0.26
42 INT169775 Positive_regulation of Positive_regulation of Opn4 1 1 0.49 0.12 0.13
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