J:Proc. Soc. Exp. Biol. Med.

This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT26468	Ghrh Positive_regulation of Localization of Gh	21	2	0.37	3.26	9.21
2	INT20133	Trh Positive_regulation of Localization of Prl	23	1	0.78	2.04	5.44
3	INT16221	Ghrh Positive_regulation of Gh	8	1	0.21	1.89	4.08
4	INT20411	Ghrh Positive_regulation of Gh1	6	1	0.56	0.62	2.47
5	INT38936	Binding of Avp and Crh	7	2	0.40	0.82	1.04
6	INT16222	Ghrh Positive_regulation of Ghrh Positive_regulation of Gh	2	1	0.02	0.51	0.99
7	INT28921	Adra2a Positive_regulation of Localization of Prl	1	2	0.24	0	0.9
8	INT44589	Negative_regulation of Oprl1 Positive_regulation of Gh1	1	1	0.22	0.53	0.87
9	INT44590	Oprl1 Positive_regulation of Gh1	1	1	0.23	0.53	0.87
10	INT12883	Binding of IL2 and POMC	1	1	0.01	0	0.81
11	INT54800	Grin1 Regulation of Gene_expression of Gh	1	1	0.01	0	0.79
12	INT54799	SST Negative_regulation of Ghrh Positive_regulation of Gh	1	1	0.00	0	0.75
13	INT54802	SST Negative_regulation of Localization of Gh	1	1	0.01	0	0.75
14	INT54801	SST Negative_regulation of Positive_regulation of Gh	1	1	0.01	0	0.75
15	INT31306	Ghrh Regulation of Localization of Gnrhr	2	1	0.14	1	0.73
16	INT45849	Nts Regulation of Localization of LH	2	1	0.35	0	0.65
17	INT17463	Trh Regulation of Localization of Prl	2	1	0.30	0.22	0.47
18	INT78121	Positive_regulation of Binding of App and 20S	1	1	0.23	0.61	0.4
19	INT78122	Binding of App and 20S	1	1	0.16	0.61	0.4
20	INT78123	Positive_regulation of App Positive_regulation of Binding of App and 20S	1	1	0.05	0.61	0.4
21	INT4638	Binding of Agt and Adarb1	3	2	0.01	0	0.34
22	INT39299	Binding of Prl and Dlst	1	1	0.20	0	0.27
23	INT32636	Slc12a3 Regulation of Localization of Nppa	1	1	0.00	0.41	0.23
24	INT45987	GRP Positive_regulation of Localization of Prl	1	1	0.18	0	0.2
25	INT45985	GRP Regulation of Localization of Prl	1	1	0.21	0	0.18
26	INT45986	GRP Negative_regulation of Localization of Prl	1	1	0.16	0	0.17
27	INT31848	SST Regulation of Localization of Gnrhr	1	1	0.01	0	0.14
28	INT31849	Ghrh Regulation of SST	1	1	0.09	0	0.14
29	INT31847	Ghrh Positive_regulation of Positive_regulation of Gh1	1	1	0.20	0	0.08
30	INT31845	Negative_regulation of Ghrh Positive_regulation of Gh1	1	1	0.18	0	0.08
31	INT45848	Nts Regulation of Localization of Prl	1	1	0.31	0	0.07

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT158	Localization of Prl	39	2431	0.81	378.96	952.2
2	INT155	Positive_regulation of Prl	22	1233	0.70	317.93	457.82
3	INT1045	Localization of LH	10	1211	0.81	87.04	456.25
4	INT467	Gene_expression of POMC	2	1048	0.78	332.8	394.16
5	INT2540	Negative_regulation of Calca	1	538	0.59	172.11	384.38
6	INT157	Positive_regulation of Localization of Prl	17	790	0.70	104.54	374.78
7	INT287	Localization of Cck	1	518	0.81	86.84	364.04
8	INT439	Localization of Gnrh1	5	976	0.81	100.96	363.25
9	INT720	Positive_regulation of POMC	5	807	0.70	237.37	353.83
10	INT876	Localization of Gh1	9	843	0.80	67.75	340.82
11	INT162	Regulation of Prl	7	794	0.62	165.01	322.24
12	INT477	Localization of Avp	9	813	0.81	131.58	300.4
13	INT161	Regulation of Localization of Prl	6	615	0.62	65.37	298.66
14	INT1893	Localization of Gh	8	1041	0.79	340.23	256.58
15	INT1665	Positive_regulation of Pag1	1	270	0.68	186.63	229.87
16	INT1212	Binding of Oprl1	1	312	0.48	28.6	225.15
17	INT1308	Localization of Pomc	1	457	0.81	66.83	217.5
18	INT767	Localization of Gnrhr	11	565	0.80	106.68	214.57
19	INT22548	Positive_regulation of Casp3	3	483	0.70	258.78	213.07
20	INT156	Negative_regulation of Prl	10	542	0.59	131.97	192.24
21	INT528	Gene_expression of Prl	10	693	0.78	217.18	192.2
22	INT2085	Positive_regulation of LH	3	441	0.70	60.15	191.02
23	INT1652	Regulation of Pomc	7	387	0.62	61.01	186.51
24	INT159	Negative_regulation of Localization of Prl	12	416	0.59	55.34	171.8
25	INT4937	Negative_regulation of Oprd1	1	224	0.59	44.51	171.11
26	INT438	Gene_expression of Crh	1	376	0.78	159.11	169.17
27	INT1114	Localization of Ins1	6	748	0.80	192.95	165.48
28	INT3448	Positive_regulation of Gh	3	521	0.69	180.03	161.18
29	INT5513	Negative_regulation of Pomc	1	295	0.59	60.9	158.63
30	INT768	Positive_regulation of Oprl1	2	179	0.70	40.05	156.93
31	INT1044	Negative_regulation of Localization of LH	2	358	0.59	25.95	151.31
32	INT880	Positive_regulation of Localization of Gh1	6	304	0.70	14.79	150.23
33	INT2451	Positive_regulation of Avp	3	355	0.70	102.66	147.69
34	INT5116	Gene_expression of IL2	1	670	0.78	291.13	146.69
35	INT2379	Positive_regulation of Localization of LH	2	349	0.70	27.86	144.53
36	INT1414	Regulation of Oprl1	1	169	0.62	32.05	139.99
37	INT1273	Gene_expression of Avp	1	356	0.78	90.56	138.7
38	INT1047	Negative_regulation of LH	3	314	0.59	53.71	135.89
39	INT416	Regulation of LH	2	253	0.62	31.48	125.55
40	INT6323	Positive_regulation of Gabrg1	1	213	0.70	45.08	124.34
41	INT2106	Regulation of Localization of LH	2	279	0.62	22.37	122.77
42	INT7395	Localization of GNRH1	1	399	0.81	62.88	117.68
43	INT4207	Regulation of Avp	3	267	0.62	63.72	115.33
44	INT1793	Localization of CGA	5	379	0.81	67.38	114.69
45	INT1530	Regulation of Gh	5	382	0.61	115.96	112.47
46	INT5940	Negative_regulation of Avp	1	236	0.59	67.86	101.2
47	INT397	Localization of SST	1	232	0.81	58.05	101.19
48	INT65500	Gene_expression of App	1	605	0.78	429.94	98.31
49	INT874	Positive_regulation of Gh1	11	244	0.70	27.17	97.98
50	INT5865	Positive_regulation of Localization of Gh	4	282	0.69	84.86	93.5
51	INT1160	Positive_regulation of Rbm39	2	122	0.57	28.19	90.28
52	INT6585	Positive_regulation of Insrr	1	110	0.52	40.67	89.9
53	INT1472	Positive_regulation of Ins1	2	349	0.69	146.2	86.36
54	INT875	Regulation of Localization of Gh1	2	166	0.62	12.87	84.97
55	INT4289	Positive_regulation of Localization of Gnrh1	2	202	0.70	12.3	84.01
56	INT5617	Localization of Nppa	15	266	0.81	83.51	83.89
57	INT2520	Negative_regulation of Ca2	1	271	0.57	72.13	83.71
58	INT339	Regulation of Trh	2	156	0.62	39.27	83.55
59	INT1309	Positive_regulation of Localization of Gnrhr	4	152	0.69	24.25	81.56
60	INT403	Localization of Trh	3	241	0.81	28.55	81.45
61	INT1498	Gene_expression of Gh	1	521	0.75	220.84	81.16
62	INT148	Positive_regulation of Gnrhr	3	182	0.70	47.44	79.64
63	INT2155	Negative_regulation of Sst	1	111	0.59	16.58	77.74
64	INT4358	Positive_regulation of Localization of Avp	1	195	0.70	30.79	77.58
65	INT3657	Gene_expression of Ins1	3	514	0.78	321.69	75.76
66	INT881	Negative_regulation of Localization of Gh1	2	164	0.58	15.1	75.28
67	INT7886	Regulation of Localization of Avp	4	146	0.62	14.53	72.99
68	INT2055	Regulation of Gnrh1	1	185	0.62	23.65	71.26
69	INT2123	Positive_regulation of Gnrh1	5	209	0.70	24.2	68.97
70	INT1988	Positive_regulation of Localization of Ins1	1	254	0.69	59.25	68.37
71	INT4637	Binding of Adarb1	1	132	0.41	14.48	67.76
72	INT1046	Gene_expression of LH	2	180	0.77	29.75	66.87
73	INT1425	Gene_expression of Rbm39	1	143	0.58	51.32	65.44
74	INT480	Negative_regulation of Localization of Avp	1	151	0.59	27.64	63.72
75	INT2056	Negative_regulation of Gnrh1	1	175	0.59	33.43	63.32
76	INT46	Localization of Ren	9	233	0.81	46.15	62.44
77	INT5095	Localization of Ghrh	12	185	0.81	28.09	62.08
78	INT3161	Regulation of Localization of Gh	3	163	0.61	35.43	59.45
79	INT1794	Regulation of Localization of CGA	2	136	0.57	13.39	59.07
80	INT770	Regulation of Localization of Gnrhr	2	127	0.61	17.91	58.23
81	INT1463	Binding of Pomc	1	129	0.48	15.89	56.27
82	INT19	Regulation of Gnrhr	1	131	0.62	36.4	55.66
83	INT314	Positive_regulation of Ren	4	212	0.70	66.68	55.56
84	INT2276	Regulation of Ins1	1	234	0.61	103.78	54.05
85	INT5623	Positive_regulation of Nppa	4	174	0.70	69.96	52.33
86	INT1781	Negative_regulation of Gh1	3	127	0.59	16.94	51.77
87	INT1977	Negative_regulation of Positive_regulation of Prl	2	98	0.59	17.06	47.88
88	INT873	Gene_expression of Gh1	2	130	0.76	26.15	46.75
89	INT20345	Gene_expression of Dbi	2	136	0.78	56.41	46.2
90	INT619	Positive_regulation of Positive_regulation of Prl	2	116	0.70	22.69	45.06
91	INT2275	Negative_regulation of Localization of Ins1	1	183	0.59	51.02	44.94
92	INT49552	Negative_regulation of Positive_regulation of Casp3	1	76	0.55	36.04	44.78
93	INT989	Negative_regulation of Trh	1	90	0.59	15.45	43.63
94	INT1894	Negative_regulation of Localization of Gh	1	168	0.58	64.12	43.56
95	INT935	Localization of Gtf3a	1	124	0.70	35.72	43.3
96	INT1474	Regulation of Localization of Ins1	2	132	0.61	25.96	43.07
97	INT957	Positive_regulation of GHRH	1	136	0.70	36.84	40.52
98	INT7824	Regulation of Cck	1	39	0.62	5.31	39.28
99	INT1931	Positive_regulation of Gene_expression of POMC	1	116	0.70	37.26	38.67
100	INT385	Gene_expression of Agt	2	182	0.78	63.62	37.91
101	INT3971	Positive_regulation of Alb	1	175	0.70	98.46	36.45
102	INT5620	Positive_regulation of Localization of Nppa	4	105	0.70	30.23	36.45
103	INT1976	Regulation of Gene_expression of Prl	2	80	0.62	20.19	36
104	INT49	Negative_regulation of Ren	1	129	0.59	37.48	35.62
105	INT1361	Negative_regulation of Gnrhr	2	118	0.58	57.77	35.54
106	INT2296	Positive_regulation of Gene_expression of Prl	5	137	0.70	36.96	35.39
107	INT7833	Positive_regulation of Cck	2	33	0.70	8.54	34.21
108	INT11764	Positive_regulation of ENG	3	78	0.61	27.65	33.69
109	INT1116	Regulation of Ren	3	103	0.62	27.66	33.26
110	INT5989	Positive_regulation of Dbi	3	79	0.49	24.38	32.56
111	INT1159	Negative_regulation of Agt	2	133	0.59	40.14	31.67
112	INT1158	Regulation of Agt	2	106	0.61	29.4	30.29
113	INT50	Negative_regulation of Localization of Ren	2	87	0.59	14.94	30.22
114	INT5100	Positive_regulation of Ghrh	5	100	0.64	24.2	30.21
115	INT6196	Regulation of Nppa	4	83	0.62	30.31	30.18
116	INT7397	Negative_regulation of Localization of GNRH1	1	86	0.59	15.45	29.78
117	INT894	Binding of Avp	2	84	0.48	29.16	29.63
118	INT47712	Positive_regulation of App	2	135	0.69	101.38	28.94
119	INT7035	Regulation of CGA	2	87	0.45	29.04	28.45
120	INT16879	Binding of Crh	4	72	0.48	21.65	28.43
121	INT4861	Localization of GRP	2	84	0.80	8.26	28.03
122	INT6174	Regulation of Gene_expression of POMC	1	49	0.61	9.75	27.69
123	INT9296	Negative_regulation of PLEK	1	100	0.57	36.65	27.52
124	INT10799	Localization of ENG	8	63	0.78	18.67	27.28
125	INT7832	Localization of Cck	2	39	0.81	6.81	26.54
126	INT3559	Negative_regulation of Localization of Gnrhr	3	73	0.58	18.89	26.41
127	INT5426	Negative_regulation of RTCA	1	58	0.51	12.34	25.74
128	INT8205	Negative_regulation of Nppa	1	77	0.59	26.43	25.72
129	INT6385	Regulation of Man2a2	1	48	0.61	7.8	24.68
130	INT5988	Localization of Dbi	1	74	0.81	17.52	24.09
131	INT9155	Gene_expression of Glul	1	60	0.77	17.97	23.95
132	INT1792	Positive_regulation of CGA	1	123	0.70	64.73	20.79
133	INT955	Gene_expression of GHRH	1	126	0.78	59.91	20.74
134	INT1512	Binding of Prl	1	73	0.48	26.22	20.63
135	INT65502	Regulation of App	1	77	0.62	52.05	19.44
136	INT9179	Positive_regulation of Localization of Ghrh	2	42	0.70	7.05	18.1
137	INT48	Positive_regulation of Localization of Ren	4	69	0.70	12.47	18.03
138	INT5618	Regulation of Localization of Nppa	6	36	0.62	13.42	17.46
139	INT3656	Positive_regulation of Gene_expression of Ins1	1	74	0.54	44.94	17.36
140	INT18660	Binding of Gnrhr	1	45	0.41	10.6	16.85
141	INT10056	Positive_regulation of Fabp6	3	77	0.59	36.99	16.8
142	INT10000	Regulation of Gene_expression of IL2	1	56	0.45	15.33	16.2
143	INT4242	Negative_regulation of Positive_regulation of Gh1	2	26	0.58	1.47	15.75
144	INT54052	Gene_expression of App	3	33	0.78	25.08	14.7
145	INT11762	Regulation of Dbi	3	40	0.62	7.83	14.48
146	INT7674	Regulation of ENG	1	42	0.30	11.41	14.44
147	INT2490	Regulation of Sct	1	44	0.62	9.45	13.11
148	INT481	Regulation of Localization of Ren	1	37	0.62	5.95	11.61
149	INT65501	Regulation of Gene_expression of App	1	56	0.62	32.51	11.48
150	INT686	Negative_regulation of Sct	1	35	0.59	9.59	11.32
151	INT18412	Binding of PLEK	1	49	0.47	17.82	10.72
152	INT3637	Positive_regulation of Localization of Trh	1	33	0.70	2.13	10.55
153	INT19010	Negative_regulation of Localization of Ghrh	2	27	0.57	4.85	10.5
154	INT50615	Positive_regulation of Positive_regulation of Insrr	1	11	0.19	5.5	10.05
155	INT3431	Negative_regulation of Positive_regulation of Oprl1	1	14	0.46	2.55	9.65
156	INT2059	Positive_regulation of Negative_regulation of Prl	1	24	0.70	5.7	9.37
157	INT5512	Negative_regulation of Dbi	1	32	0.36	7.33	9.1
158	INT1224	Gene_expression of Fabp6	1	34	0.64	23.69	9.08
159	INT386	Positive_regulation of Gene_expression of Agt	2	37	0.70	15.92	8.73
160	INT7673	Negative_regulation of ENG	1	31	0.42	7.9	8.61
161	INT1138	Positive_regulation of IgG-2a	2	16	0.68	5.59	8.11
162	INT113	Positive_regulation of MBD2	3	33	0.49	6.76	7.49
163	INT56031	Positive_regulation of App	4	25	0.69	13.46	7.37
164	INT9785	Negative_regulation of Positive_regulation of Gnrh1	1	18	0.43	1.88	7.35
165	INT4299	Positive_regulation of Gene_expression of Gh1	1	27	0.50	5.24	7.31
166	INT11150	Positive_regulation of Dlst	1	31	0.51	9.01	6.63
167	INT84965	Gene_expression of MAOA	1	15	0.75	6.9	6.06
168	INT71220	Positive_regulation of Casp1	1	15	0.38	10.23	5.84
169	INT3614	Negative_regulation of Gene_expression of Gh1	1	16	0.42	6.8	5.74
170	INT18345	Positive_regulation of Positive_regulation of Gnrhr	1	16	0.42	4.99	4.91
171	INT11298	Gene_expression of Ido1	1	6	0.58	6.71	4.85
172	INT78116	Positive_regulation of Gene_expression of App	3	12	0.70	10.78	4.52
173	INT205	Negative_regulation of Cbr1	1	10	0.58	4.23	4.29
174	INT10842	Transcription of Gh	1	18	0.64	2.94	4.13
175	INT4360	Gene_expression of Hypism	1	29	0.22	38.1	4.07
176	INT9013	Localization of Grp	1	9	0.73	0.63	3.99
177	INT26368	Positive_regulation of S100A6	2	30	0.45	9.72	3.89
178	INT17620	Positive_regulation of Gnrh1	1	23	0.70	9.77	3.79
179	INT10168	Positive_regulation of Localization of Gtf3a	1	16	0.60	3.55	3.75
180	INT27642	Regulation of Gene_expression of Dbi	1	10	0.44	2.55	3.66
181	INT56916	Positive_regulation of Mir125b-1	2	3	0.10	1.14	3.22
182	INT21679	Negative_regulation of PTGER1	1	10	0.26	4.59	2.85
183	INT32983	Localization of Lct	2	8	0.47	0.42	2.6
184	INT14877	Positive_regulation of Localization of GRP	2	8	0.46	0.1	2.47
185	INT3608	Regulation of Cbr1	1	6	0.45	2.28	2.44
186	INT12133	Regulation of Localization of ENG	3	3	0.03	0.57	2.24
187	INT16527	Negative_regulation of Positive_regulation of Ghrh	2	6	0.43	1.01	2.23
188	INT25461	Negative_regulation of Regulation of Nppa	1	2	0.43	0.22	1.97
189	INT35370	Negative_regulation of Dlst	1	6	0.32	2.58	1.9
190	INT81169	Localization of Nr4a2	1	1	0.68	0	1.71
191	INT45719	Positive_regulation of Transcription of Gh	1	5	0.47	0.68	1.66
192	INT60053	Regulation of Hibch	2	1	0.06	1.98	1.65
193	INT3607	Gene_expression of Cbr1	1	4	0.59	1.17	1.48
194	INT25544	Positive_regulation of Hapln1	1	3	0.12	8.58	1.44
195	INT32519	Positive_regulation of Terc	1	5	0.36	4.41	1.41
196	INT56914	Gene_expression of Mir125b-1	1	2	0.14	0.47	1.36
197	INT43815	Localization of Mapre1	2	1	0.14	0.16	1.21
198	INT56915	Positive_regulation of Positive_regulation of IgG-2a	1	1	0.09	0.13	1.09
199	INT3609	Regulation of Gene_expression of Cbr1	1	1	0.27	0.74	1.08
200	INT40249	Regulation of Regulation of Ren	1	4	0.36	0.83	1.05