J:Psychopharmacology (Berl)

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT275097 Twist1 Regulation of Ltp 1 2 0.01 0.37 0.96
2 INT221257 Pde5a Positive_regulation of PRKG1 3 1 0.07 0.19 0.86
3 INT257222 Binding of Ltp and Pde5a 2 1 0.07 0.14 0.75
4 INT292598 CNR1 Regulation of ABAT 1 1 0.08 0.32 0.75
5 INT343599 Gys1 Regulation of Tst 1 1 0.01 0 0.75
6 INT292599 CNR1 Regulation of Localization of ABAT 1 1 0.08 0.32 0.75
7 INT263236 DAG1 Positive_regulation of Prkcg 2 1 0.01 0.31 0.7
8 INT235082 CA2 Positive_regulation of NOS1 2 1 0.11 0.62 0.63
9 INT275063 CA2 Positive_regulation of Positive_regulation of CAMK4 1 1 0.01 0 0.59
10 INT343597 Gys1 Regulation of Transcription of Gria2 1 1 0.00 0 0.55
11 INT290956 Binding of Slc3a1 and Lsd 1 1 0.03 0 0.51
12 INT275100 Pde4a Negative_regulation of RTP3 1 1 0.00 0.51 0.42
13 INT275087 Pde2a Negative_regulation of stm 1 1 0.01 0.51 0.42
14 INT275089 Pde4a Negative_regulation of stm 1 1 0.02 0.51 0.42
15 INT275104 Pde2a Negative_regulation of RTP3 1 1 0.00 0.51 0.42
16 INT275099 Pde9a Negative_regulation of RTP3 1 1 0.00 0.51 0.39
17 INT275093 Pde9a Negative_regulation of stm 1 1 0.00 0.51 0.39
18 INT275096 Pde9a Regulation of Ltp 1 1 0.00 0.11 0.35
19 INT275098 Pde9a Regulation of RTP3 1 1 0.00 0.11 0.35
20 INT275094 Pde5a Regulation of Ltp 1 1 0.05 0 0.35
21 INT273130 Negative_regulation of Binding of Drd2 and Hp 1 1 0.05 0 0.28
22 INT273129 Binding of Drd2 and Hp 1 1 0.04 0 0.28
23 INT290957 Lsd Positive_regulation of Gene_expression of Egr2 1 1 0.11 0.1 0.26
24 INT275092 Twist1 Regulation of stm 1 1 0.00 0 0.25
25 INT216075 ATD Regulation of Cfp 1 1 0.07 0.11 0.11
26 INT275064 Binding of CA2 and CALM1 2 1 0.06 0 0.07
27 INT275102 Prkcg Regulation of CREB1 1 1 0.01 0 0.06
28 INT275101 CAMK4 Positive_regulation of Prkcg 1 1 0.01 0 0.06
29 INT275103 CA2 Positive_regulation of Prkcg 1 1 0.01 0 0.06
30 INT275105 CALM3 Positive_regulation of Prkcg 1 1 0.00 0 0.06
31 INT200428 Sdcbp Positive_regulation of Gene_expression of Gfap 1 1 0.04 0.15 0.04
32 INT275090 Twist1 Positive_regulation of Gene_expression of Pde5a 1 1 0.02 0.62 0.04
33 INT275095 Twist1 Positive_regulation of Pde5a 1 1 0.03 0.62 0.04
34 INT157755 Tmx1 Regulation of Positive_regulation of Casp3 1 1 0.15 0 0
35 INT163585 Lep Positive_regulation of Gene_expression of Epm2a 1 1 0.03 0.14 0
36 INT275091 Negative_regulation of Twist1 Positive_regulation of Pde5a 1 1 0.02 0.06 0
37 INT157754 Tmx1 Regulation of Gene_expression of Casp3 1 1 0.15 0 0
38 INT163584 Lep Positive_regulation of Epm2a 1 1 0.03 0.13 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 1 3083 0.78 894.43 1639.02
2 INT158 Localization of Prl 8 2431 0.81 378.96 952.2
3 INT7114 Positive_regulation of Ltp 9 1192 0.62 290.76 755.77
4 INT155 Positive_regulation of Prl 3 1233 0.70 317.93 457.82
5 INT443 Localization of POMC 3 1020 0.81 284.52 443.17
6 INT64202 Positive_regulation of Trpv1 1 643 0.70 249.66 397.42
7 INT467 Gene_expression of POMC 1 1048 0.78 332.8 394.16
8 INT157 Positive_regulation of Localization of Prl 3 790 0.70 104.54 374.78
9 INT720 Positive_regulation of POMC 1 807 0.70 237.37 353.83
10 INT5660 Binding of Oprd1 7 477 0.48 71.86 342.06
11 INT162 Regulation of Prl 1 794 0.62 165.01 322.24
12 INT738 Regulation of POMC 2 459 0.62 111.19 243.74
13 INT738 Regulation of POMC 3 459 0.62 111.19 243.74
14 INT6665 Gene_expression of FOS 17 520 0.77 165.31 217.66
15 INT1308 Localization of Pomc 10 457 0.81 66.83 217.5
16 INT2651 Positive_regulation of Pomc 4 403 0.70 95.72 206.24
17 INT6354 Localization of Gabrg1 2 321 0.74 41.41 186.74
18 INT7506 Negative_regulation of Ltp 3 267 0.46 91.01 176.8
19 INT159 Negative_regulation of Localization of Prl 1 416 0.59 55.34 171.8
20 INT438 Gene_expression of Crh 2 376 0.78 159.11 169.17
21 INT739 Negative_regulation of POMC 1 358 0.59 102.28 166.77
22 INT1303 Negative_regulation of Npr1 1 278 0.55 35.1 156.78
23 INT6042 Binding of Oprm1 8 248 0.48 31.77 154.34
24 INT120811 Gene_expression of Gopc 2 1174 0.59 428.49 150.55
25 INT7628 Gene_expression of Ltp 8 273 0.77 70.21 147.87
26 INT14843 Gene_expression of Gabrg1 2 301 0.77 62.63 139.16
27 INT65600 Positive_regulation of Casp3 13 376 0.70 198.44 128.03
28 INT5842 Gene_expression of Gfap 12 372 0.78 153.71 127.71
29 INT5931 Regulation of Oprm1 1 149 0.62 18.15 125.93
30 INT6822 Gene_expression of Pdyn 10 215 0.78 35.99 125.76
31 INT4824 Positive_regulation of Tacr1 1 169 0.70 66.1 123.46
32 INT6128 Positive_regulation of Localization of POMC 1 256 0.70 68.77 121.64
33 INT64201 Negative_regulation of Trpv1 2 203 0.59 79.18 119.75
34 INT62124 Gene_expression of NOS1 1 444 0.78 218.08 114.85
35 INT48593 Positive_regulation of NOS1 2 420 0.68 226.15 114.71
36 INT90091 Gene_expression of GOPC 8 967 0.67 366.22 103.6
37 INT5587 Regulation of Fos 1 191 0.62 40.81 99.7
38 INT1351 Gene_expression of Pag1 1 131 0.57 89.48 98.76
39 INT17459 Positive_regulation of Gene_expression of FOS 5 182 0.67 53.45 96.38
40 INT74058 Gene_expression of Nos1 4 260 0.78 80.04 95.71
41 INT29971 Gene_expression of Oprk1 4 126 0.78 35.32 93.97
42 INT203 Positive_regulation of Pomc 1 257 0.70 90.56 92.84
43 INT1281 Negative_regulation of Maoa 1 203 0.59 22.47 91.66
44 INT69764 Positive_regulation of Cnr1 4 126 0.70 67.8 91.49
45 INT48767 Negative_regulation of NOS1 1 312 0.59 154.25 90.32
46 INT18032 Positive_regulation of Oprk1 9 108 0.70 30.78 89.7
47 INT15898 Positive_regulation of Prkaca 3 199 0.70 50.89 87.54
48 INT13036 Positive_regulation of Positive_regulation of Ltp 1 105 0.51 23.71 77.66
49 INT12536 Localization of Prkcg 1 101 0.80 36.37 73.81
50 INT5852 Gene_expression of Penk 5 167 0.78 44.44 71.13
51 INT14049 Positive_regulation of GRIN1 1 102 0.70 48.31 71.06
52 INT5843 Positive_regulation of Gfap 4 184 0.70 108.2 70.21
53 INT171145 Positive_regulation of Fig4 2 274 0.59 93.55 69.81
54 INT53964 Negative_regulation of Prkaca 1 131 0.58 38.76 69.52
55 INT13276 Regulation of Ltp 3 107 0.53 30.78 69.13
56 INT5861 Gene_expression of Egr1 1 203 0.78 49.35 68.13
57 INT8347 Gene_expression of SST 2 181 0.78 104.59 65.45
58 INT6926 Regulation of Pag1 1 72 0.39 55.79 65.09
59 INT24989 Positive_regulation of Cfp 1 125 0.61 29.55 64.9
60 INT6894 Gene_expression of CNR1 2 168 0.78 74.07 62.84
61 INT18981 Gene_expression of ABAT 1 78 0.68 38.35 61.36
62 INT5016 Negative_regulation of Crh 1 129 0.59 36.74 59.28
63 INT7032 Positive_regulation of Pdyn 4 94 0.66 26.51 58.83
64 INT13938 Positive_regulation of Nkx1-1 1 64 0.68 30.83 58.75
65 INT169926 Positive_regulation of Gopc 1 416 0.46 157.8 58.67
66 INT31116 Gene_expression of Casp3 3 192 0.78 78.21 57.43
67 INT5356 Positive_regulation of FOS 7 153 0.69 54.21 56.74
68 INT1463 Binding of Pomc 4 129 0.48 15.89 56.27
69 INT17458 Negative_regulation of Gene_expression of FOS 1 98 0.57 36.77 55.69
70 INT119528 Positive_regulation of Camk2a 2 135 0.70 26.13 54.7
71 INT7898 Gene_expression of Homer1 4 123 0.78 31.52 53.67
72 INT8071 Positive_regulation of Gria1 1 102 0.70 26.61 53.37
73 INT5704 Binding of Slc3a1 5 78 0.43 8.52 51.78
74 INT5118 Regulation of SST 1 97 0.62 34.35 51.74
75 INT5858 Positive_regulation of Drd1a 1 66 0.69 4.51 51.73
76 INT62630 Positive_regulation of CNR1 1 86 0.70 40.34 51.51
77 INT19488 Localization of ABAT 2 56 0.69 21.51 50.56
78 INT1197 Negative_regulation of Localization of POMC 1 109 0.59 28.29 48.02
79 INT6864 Positive_regulation of Gene_expression of Gfap 2 110 0.70 59.01 47.07
80 INT6979 Positive_regulation of CA2 1 206 0.67 50.79 44.97
81 INT66383 Phosphorylation of Prkaca 1 143 0.80 30.85 43.38
82 INT7828 Positive_regulation of Oprd1 2 55 0.69 14.11 42.86
83 INT173693 Localization of Gopc 1 249 0.65 70.49 38.81
84 INT16455 Gene_expression of Drd2 1 116 0.78 22.71 38.47
85 INT6417 Negative_regulation of ABAT 1 49 0.51 19.6 36.81
86 INT64558 Negative_regulation of Nos1 1 88 0.58 26.76 36.78
87 INT17736 Gene_expression of Cfp 3 111 0.65 40.68 36.61
88 INT30169 Negative_regulation of Pde4a 3 107 0.58 81 36.23
89 INT13501 Binding of Drd2 1 65 0.48 23.76 35.6
90 INT109434 Phosphorylation of Mapk1 2 110 0.82 61.64 34.05
91 INT5489 Localization of CA2 1 172 0.80 39.46 33.56
92 INT45365 Negative_regulation of Cfp 5 68 0.57 25.44 32.11
93 INT7787 Positive_regulation of Akr1d1 1 52 0.66 3.55 31.71
94 INT5505 Regulation of Localization of Pomc 1 54 0.61 6.96 30.77
95 INT32165 Binding of CALM1 2 92 0.48 24.19 29.57
96 INT67912 Gene_expression of GRIN1 3 75 0.77 28.99 29.28
97 INT6765 Localization of Oprl1 1 49 0.81 5.11 28.87
98 INT15610 Localization of GOPC 1 223 0.65 68.26 28.7
99 INT1166 Negative_regulation of Dbh 1 56 0.59 12.54 28.26
100 INT5653 Positive_regulation of ELANE 1 136 0.70 72.78 27.94
101 INT177581 Regulation of Fig4 2 113 0.41 39.26 27.75
102 INT2650 Positive_regulation of Slc3a1 1 50 0.57 2.95 27.52
103 INT54467 Localization of Ltp 9 41 0.58 8.86 26.88
104 INT32826 Positive_regulation of Gene_expression of Ltp 1 52 0.45 10.34 26.8
105 INT2609 Localization of ELANE 5 111 0.81 50.22 26.63
106 INT29107 Regulation of Oprk1 1 31 0.45 6.16 26.61
107 INT49850 Negative_regulation of PDE4A 1 105 0.58 76.91 26.59
108 INT13995 Gene_expression of gr 1 96 0.74 48.21 26.54
109 INT79395 Gene_expression of Twist1 1 193 0.77 100.06 26.34
110 INT7899 Positive_regulation of Gene_expression of Homer1 1 41 0.70 7.29 25.98
111 INT48979 Regulation of Gene_expression of FOS 2 52 0.61 14.4 25.95
112 INT11014 Phosphorylation of CREB1 3 72 0.81 26.35 25.64
113 INT61664 Regulation of GRIN1 4 38 0.60 16.45 25.35
114 INT74688 Regulation of Nos1 2 55 0.62 22.16 25.3
115 INT101483 Gene_expression of Lep 2 159 0.78 104.77 25.12
116 INT172458 Regulation of Gopc 2 155 0.53 62.57 24.86
117 INT12484 Binding of Drd2 1 45 0.48 15.17 24.72
118 INT12484 Binding of Drd2 1 45 0.48 15.17 24.72
119 INT48766 Regulation of NOS1 1 73 0.61 37.01 24.59
120 INT13334 Gene_expression of Drd1a 1 43 0.62 7.73 24.43
121 INT151758 Gene_expression of PYCARD 3 91 0.63 14.54 24.27
122 INT47818 Positive_regulation of Homer1 1 48 0.70 11.11 24.05
123 INT4781 Gene_expression of TH 1 68 0.73 26.92 24.01
124 INT101225 Positive_regulation of Gria2 2 62 0.64 28.1 23.93
125 INT49553 Regulation of Gene_expression of Gfap 6 42 0.62 17.04 23.65
126 INT6866 Regulation of Gfap 5 51 0.61 19.6 23.56
127 INT47741 Negative_regulation of Flvcr2 1 43 0.51 5.72 23.37
128 INT6868 Gene_expression of GFAP 1 136 0.78 84.65 22.7
129 INT78571 Positive_regulation of Grm5 3 35 0.69 11.81 22.45
130 INT5905 Negative_regulation of ELANE 2 113 0.59 47.43 22.09
131 INT28728 Regulation of Cfp 3 49 0.46 13.15 21.43
132 INT171820 Localization of Fig4 2 144 0.65 27.38 20.88
133 INT440 Regulation of Gene_expression of Crh 1 44 0.62 17.71 20.73
134 INT79349 Gene_expression of Sert1 7 58 0.77 12.7 20.65
135 INT105021 Binding of GOPC 3 187 0.40 60.39 20.38
136 INT76336 Negative_regulation of PDE5A 5 192 0.59 112.02 20.09
137 INT81210 Positive_regulation of PRKG1 1 71 0.70 26.83 19.89
138 INT68347 Negative_regulation of Cyp2d4 1 34 0.58 7.62 18.35
139 INT30197 Positive_regulation of Ubqln1 3 26 0.08 2.07 18.28
140 INT21132 Gene_expression of GABRB3 2 36 0.33 11.32 17.61
141 INT6728 Gene_expression of Ednra 3 43 0.65 13.41 17.38
142 INT7020 Negative_regulation of Drd1a 2 25 0.57 1.84 17.1
143 INT209 Positive_regulation of Pde5a 2 30 0.21 2.54 16.31
144 INT171666 Regulation of GOPC 2 117 0.39 40.41 15.47
145 INT26729 Negative_regulation of Drd2 2 28 0.55 9.32 15.17
146 INT29086 Negative_regulation of Sert1 7 37 0.58 7.49 14.98
147 INT5324 Binding of Htr2a 1 23 0.47 7.14 14.66
148 INT66611 Localization of Cfp 1 22 0.65 7.04 14.64
149 INT91913 Regulation of GRIN3B 1 16 0.61 11.48 14.44
150 INT5599 Regulation of Drd2 1 25 0.52 3.07 13.31
151 INT65965 Gene_expression of Adcyap1 1 52 0.78 22.53 13.14
152 INT197366 Positive_regulation of Localization of Ltp 5 18 0.39 3.8 13.08
153 INT15246 Regulation of FOS 3 32 0.60 15.34 12.94
154 INT174844 Binding of Fig4 1 81 0.41 18.03 12.87
155 INT21987 Positive_regulation of Rorb 2 30 0.33 12.7 12.24
156 INT81626 Positive_regulation of Positive_regulation of Casp3 1 34 0.69 16.75 12.18
157 INT107522 Regulation of Grm5 1 9 0.44 6.42 11.46
158 INT10874 Negative_regulation of Twist1 8 89 0.50 36.84 11.32
159 INT12444 Binding of Gabrd 1 26 0.48 4.7 11.23
160 INT6044 Regulation of Binding of Oprm1 1 16 0.61 3.01 11.11
161 INT192967 Gene_expression of Hp 10 14 0.43 8.06 11.01
162 INT273123 Binding of Hp 13 1 0.25 3.56 10.9
163 INT67915 Negative_regulation of Gtpbp4 1 18 0.33 6.31 10.17
164 INT95207 Negative_regulation of Pde5a 5 46 0.58 32.01 10.14
165 INT75955 Gene_expression of Drd3 1 19 0.77 4.39 10.07
166 INT35835 Positive_regulation of Htr2a 1 17 0.67 10.68 9.81
167 INT16580 Negative_regulation of Htr2a 1 18 0.57 3.8 9.63
168 INT8249 Positive_regulation of Cubn 1 15 0.66 4.05 9.35
169 INT15242 Regulation of Gene_expression of Homer1 1 14 0.62 4.33 9.28
170 INT54588 Positive_regulation of CREB1 3 38 0.67 12.01 9.18
171 INT78570 Negative_regulation of Grm5 1 15 0.57 5.45 9.17
172 INT48978 Negative_regulation of FOS 1 41 0.57 11.94 9.14
173 INT34106 Negative_regulation of Htr1a 3 14 0.57 4.72 8.73
174 INT6727 Positive_regulation of Ednra 1 27 0.64 18.75 8.71
175 INT105777 Gene_expression of Pde4a 6 30 0.76 12.67 8.52
176 INT43820 Positive_regulation of Twist1 2 75 0.59 42.15 8.47
177 INT17333 Positive_regulation of Positive_regulation of FOS 1 17 0.67 6.06 8.4
178 INT126848 Positive_regulation of Phosphorylation of Mapk1 2 30 0.50 15.94 8.34
179 INT148703 Gene_expression of NOVA2 2 73 0.65 18.05 8.3
180 INT71785 Gene_expression of MAPK3 1 22 0.75 11.35 8.21
181 INT30382 Negative_regulation of Ednra 1 21 0.42 12.06 8.19
182 INT81153 Gene_expression of Hcrt 2 31 0.77 6.04 8.16
183 INT119411 Negative_regulation of Tst 3 22 0.38 7.84 7.63
184 INT55185 Binding of Sert1 7 26 0.48 4.43 7.57
185 INT171715 Gene_expression of Sema5b 9 46 0.31 6.46 7.48
186 INT102572 Gene_expression of Ccnd1 1 79 0.69 56.37 7.34
187 INT90715 Gene_expression of Egr2 1 12 0.73 1.64 7.17
188 INT60196 Binding of FOS 1 33 0.47 13.11 6.95
189 INT155989 Negative_regulation of Localization of ABAT 1 7 0.38 1.29 6.95
190 INT155988 Regulation of Localization of ABAT 1 5 0.24 2.19 6.59
191 INT84779 Positive_regulation of Hcrt 2 9 0.70 1.27 6.21
192 INT79348 Positive_regulation of Sert1 1 11 0.64 4.32 6.17
193 INT116617 Phosphorylation of Rorb 1 15 0.07 3.43 6.12
194 INT35452 Gene_expression of Htr2a 2 11 0.65 5.11 6.1
195 INT48911 Binding of NOS1 2 24 0.40 11.21 5.89
196 INT30195 Gene_expression of Ubqln1 2 12 0.10 1.09 5.89
197 INT5490 Binding of CA2 1 52 0.36 9.73 5.53
198 INT59718 Regulation of Htr1a 1 10 0.44 3.9 5.44
199 INT139749 Regulation of Ubqln1 3 10 0.02 2.47 5.38
200 INT202934 Localization of NOVA2 2 12 0.44 3.9 5.36
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