J:Psychopharmacology (Berl.)

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT7022 Drd1a Positive_regulation of Npr1 6 1 0.05 0.26 4.32
2 INT7436 CFP Positive_regulation of Binding of POMC 1 2 0.02 0.18 3.35
3 INT18786 Binding of Adra2a and Nisch 2 2 0.19 0 1.7
4 INT13205 Oprd1 Negative_regulation of Npr1 2 1 0.01 0 1.16
5 INT74517 Binding of Casp3 and Cnrip1 1 1 0.31 0 0.51
6 INT67984 GHRH Regulation of PRL 1 1 0.22 0 0.49
7 INT67983 Positive_regulation of HTR1B Positive_regulation of Localization of GHRH 1 1 0.42 0 0.47
8 INT60935 Negative_regulation of Maoa Negative_regulation of Apcs 1 1 0.33 0.17 0.46
9 INT34987 Adra2a Positive_regulation of Localization of Gnrhr 1 1 0.43 0 0.4
10 INT34786 KCNA1 Positive_regulation of Localization of PRL 1 2 0.05 0 0.4
11 INT150196 Grm5 Regulation of Grin2b 1 1 0.45 0 0.36
12 INT76756 Man2a2 Regulation of D1Jor3 1 1 0.01 0.25 0.3
13 INT34784 DIO2 Regulation of Localization of GHRH 1 1 0.00 0 0.25
14 INT34785 DIO2 Positive_regulation of Localization of GHRH 1 1 0.01 0 0.25
15 INT52294 Binding of Htr3a and Tcra-V11.1 1 1 0.27 0.37 0.14
16 INT85358 Gm2078 Regulation of Prl 1 1 0.00 0 0
17 INT89016 Oprd1 Negative_regulation of Drd1a 1 1 0.06 0 0
18 INT90319 Binding of Slc6a3 and Positive_regulation of Regulation of Oprl1 1 1 0.14 0 0
19 INT139032 Binding of Oprm1 and Tp63 1 1 0.25 0.05 0
20 INT139033 Positive_regulation of Binding of Oprm1 and Tp63 1 1 0.32 0.05 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 13 3083 0.78 894.43 1639.02
2 INT796 Gene_expression of Penk 10 1902 0.78 275.47 1057.59
3 INT158 Localization of Prl 7 2431 0.81 378.96 952.2
4 INT6483 Gene_expression of TNF 1 3152 0.78 2515.62 929.82
5 INT7114 Positive_regulation of Ltp 1 1192 0.62 290.76 755.77
6 INT3439 Localization of Abat 4 1017 0.78 112.39 727.06
7 INT5202 Positive_regulation of Gene_expression of Fos 6 1163 0.70 319.28 684
8 INT292 Localization of Penk 1 876 0.81 88.44 669.14
9 INT728 Positive_regulation of Penk 12 1068 0.70 186.9 636.87
10 INT797 Regulation of Penk 7 812 0.62 111.13 542.24
11 INT5228 Positive_regulation of Fos 14 934 0.70 209.8 503.87
12 INT155 Positive_regulation of Prl 4 1233 0.70 317.93 457.82
13 INT443 Localization of POMC 3 1020 0.81 284.52 443.17
14 INT5895 Gene_expression of Oprm1 5 525 0.78 120.67 407.29
15 INT1395 Negative_regulation of Penk 2 537 0.59 87.33 389.81
16 INT6056 Negative_regulation of Gene_expression of Fos 2 601 0.59 193.05 386.84
17 INT6580 Negative_regulation of Ptgs1 1 929 0.59 381.53 376.26
18 INT157 Positive_regulation of Localization of Prl 3 790 0.70 104.54 374.78
19 INT720 Positive_regulation of POMC 3 807 0.70 237.37 353.83
20 INT876 Localization of Gh1 7 843 0.80 67.75 340.82
21 INT162 Regulation of Prl 3 794 0.62 165.01 322.24
22 INT5540 Positive_regulation of Oprm1 1 344 0.70 76.77 319.71
23 INT4941 Positive_regulation of Oprd1 2 345 0.70 74.26 304.41
24 INT1352 Localization of Acot1 8 728 0.80 73.01 296.01
25 INT886 Gene_expression of Pomc 3 676 0.78 129.87 295.98
26 INT5379 Gene_expression of Fos 2 656 0.78 255.5 292.54
27 INT5591 Regulation of Gene_expression of Fos 1 425 0.62 129.06 265.78
28 INT1893 Localization of Gh 8 1041 0.79 340.23 256.58
29 INT2909 Positive_regulation of Abat 2 334 0.70 62.1 256.43
30 INT3948 Regulation of Cck 1 291 0.62 58.07 255.88
31 INT5501 Regulation of Oprd1 7 283 0.62 55.1 249.9
32 INT1562 Localization of Crh 3 499 0.81 126.74 236.68
33 INT5597 Gene_expression of Pdyn 2 433 0.78 62.97 235.47
34 INT1665 Positive_regulation of Pag1 8 270 0.68 186.63 229.87
35 INT9987 Gene_expression of Abat 3 296 0.78 95.46 226.34
36 INT6406 Binding of Oprm1 6 280 0.48 40.54 226.26
37 INT1212 Binding of Oprl1 1 312 0.48 28.6 225.15
38 INT11009 Phosphorylation of Creb1 2 458 0.82 111.34 221.97
39 INT6293 Gene_expression of Oprm1 4 312 0.78 48.73 215.61
40 INT767 Localization of Gnrhr 5 565 0.80 106.68 214.57
41 INT22548 Positive_regulation of Casp3 15 483 0.70 258.78 213.07
42 INT48955 Gene_expression of Nos2 10 753 0.78 403.87 208.08
43 INT798 Positive_regulation of Gene_expression of Penk 4 394 0.70 78.53 203.07
44 INT11313 Positive_regulation of Il6 2 526 0.70 331.27 201.59
45 INT2211 Negative_regulation of Abat 4 267 0.59 66.51 200.98
46 INT156 Negative_regulation of Prl 1 542 0.59 131.97 192.24
47 INT528 Gene_expression of Prl 4 693 0.78 217.18 192.2
48 INT2085 Positive_regulation of LH 2 441 0.70 60.15 191.02
49 INT1652 Regulation of Pomc 5 387 0.62 61.01 186.51
50 INT24326 Gene_expression of Ngf 1 346 0.78 218.67 184.71
51 INT4803 Transcription of Penk 6 435 0.72 59.09 182.4
52 INT12602 Negative_regulation of Oprm1 2 190 0.59 36.11 177.85
53 INT159 Negative_regulation of Localization of Prl 1 416 0.59 55.34 171.8
54 INT4937 Negative_regulation of Oprd1 2 224 0.59 44.51 171.11
55 INT438 Gene_expression of Crh 3 376 0.78 159.11 169.17
56 INT4768 Positive_regulation of OPRM1 1 212 0.70 31.09 164.28
57 INT2366 Binding of Cck 1 192 0.48 30.64 163.46
58 INT3448 Positive_regulation of Gh 13 521 0.69 180.03 161.18
59 INT5513 Negative_regulation of Pomc 8 295 0.59 60.9 158.63
60 INT2910 Regulation of Abat 1 169 0.62 36.95 153.53
61 INT4829 Positive_regulation of Localization of Abat 1 199 0.55 20.91 150.48
62 INT880 Positive_regulation of Localization of Gh1 1 304 0.70 14.79 150.23
63 INT425 Localization of PRL 10 455 0.81 189.64 144.8
64 INT2780 Regulation of Gene_expression of Penk 2 265 0.62 32.45 143.88
65 INT1414 Regulation of Oprl1 3 169 0.62 32.05 139.99
66 INT1273 Gene_expression of Avp 1 356 0.78 90.56 138.7
67 INT5061 Negative_regulation of Mme 1 306 0.59 51.97 136.9
68 INT4658 Binding of OPRM1 4 188 0.48 25.96 136.24
69 INT1047 Negative_regulation of LH 1 314 0.59 53.71 135.89
70 INT48953 Positive_regulation of Nos2 1 486 0.70 239.85 131.87
71 INT5497 Positive_regulation of Crh 10 299 0.70 125.54 131.14
72 INT5595 Positive_regulation of Pdyn 1 223 0.70 48.37 130.14
73 INT64161 Positive_regulation of Prkca 4 213 0.70 85.06 129.91
74 INT1614 Gene_expression of Oprl1 2 164 0.78 31.43 127.74
75 INT695 Binding of POMC 1 304 0.48 56.66 126.85
76 INT416 Regulation of LH 1 253 0.62 31.48 125.55
77 INT6323 Positive_regulation of Gabrg1 2 213 0.70 45.08 124.34
78 INT252 Localization of GH1 5 529 0.80 227.4 122.05
79 INT6128 Positive_regulation of Localization of POMC 1 256 0.70 68.77 121.64
80 INT14151 Gene_expression of Casp3 15 311 0.78 140.26 120.68
81 INT1438 Localization of Pomc 5 360 0.81 101.26 116.47
82 INT4207 Regulation of Avp 1 267 0.62 63.72 115.33
83 INT62124 Gene_expression of NOS1 2 444 0.78 218.08 114.85
84 INT48593 Positive_regulation of NOS1 2 420 0.68 226.15 114.71
85 INT1530 Regulation of Gh 3 382 0.61 115.96 112.47
86 INT65731 Gene_expression of Cnr1 1 234 0.78 63.82 109.34
87 INT7627 Negative_regulation of Positive_regulation of Ltp 1 162 0.50 41.2 106.27
88 INT49171 Gene_expression of Nos1 5 241 0.78 140.7 104.76
89 INT915 Positive_regulation of PRL 5 342 0.70 141.96 104.31
90 INT114 Binding of Oprl1 1 139 0.48 23 103.35
91 INT1898 Regulation of Crh 3 220 0.62 61.33 102.64
92 INT5906 Negative_regulation of Oprm1 2 125 0.59 19.58 101.57
93 INT5940 Negative_regulation of Avp 1 236 0.59 67.86 101.2
94 INT397 Localization of SST 2 232 0.81 58.05 101.19
95 INT5587 Regulation of Fos 3 191 0.62 40.81 99.7
96 INT874 Positive_regulation of Gh1 3 244 0.70 27.17 97.98
97 INT3537 Positive_regulation of Car2 3 413 0.56 103.51 94.35
98 INT5865 Positive_regulation of Localization of Gh 5 282 0.69 84.86 93.5
99 INT203 Positive_regulation of Pomc 4 257 0.70 90.56 92.84
100 INT1281 Negative_regulation of Maoa 9 203 0.59 22.47 91.66
101 INT48767 Negative_regulation of NOS1 5 312 0.59 154.25 90.32
102 INT64158 Negative_regulation of Prkca 2 121 0.59 29.8 88.66
103 INT4798 Gene_expression of Nts 2 169 0.77 29.56 86.04
104 INT2149 Positive_regulation of Oxt 2 181 0.70 24.8 85.43
105 INT3766 Positive_regulation of Localization of Acot1 1 192 0.69 21.8 85.35
106 INT21793 Positive_regulation of Ngf 1 154 0.70 94.78 85.27
107 INT875 Regulation of Localization of Gh1 1 166 0.62 12.87 84.97
108 INT914 Positive_regulation of GH1 2 292 0.69 100.7 84.91
109 INT339 Regulation of Trh 1 156 0.62 39.27 83.55
110 INT92434 Phosphorylation of Mapk1 9 287 0.82 91.65 83.46
111 INT5590 Negative_regulation of Fos 1 144 0.59 40.94 81.98
112 INT1309 Positive_regulation of Localization of Gnrhr 1 152 0.69 24.25 81.56
113 INT1498 Gene_expression of Gh 2 521 0.75 220.84 81.16
114 INT148 Positive_regulation of Gnrhr 3 182 0.70 47.44 79.64
115 INT64636 Positive_regulation of Gene_expression of Nos2 3 242 0.70 147.52 79.53
116 INT920 Localization of PLOD1 2 223 0.81 42.25 78.7
117 INT16654 Gene_expression of Insrr 3 138 0.46 58.96 75.68
118 INT1353 Negative_regulation of Localization of Acot1 3 153 0.53 15.05 75.17
119 INT1497 Negative_regulation of Gh 4 415 0.59 192.95 74.71
120 INT10274 Positive_regulation of Il1b 1 123 0.70 79.76 73.56
121 INT7028 Localization of Pdyn 2 90 0.81 8.89 73.54
122 INT1080 Negative_regulation of Ache 1 343 0.59 108.51 72.4
123 INT10359 Gene_expression of Ifng 1 159 0.78 79.6 72.14
124 INT31774 Positive_regulation of Vta1 4 67 0.44 14.52 71.79
125 INT8962 Gene_expression of Cpe 1 110 0.71 39.67 71.67
126 INT5993 Positive_regulation of Nts 1 122 0.70 26.82 70.45
127 INT451 Regulation of Oxt 1 142 0.62 22.07 69.42
128 INT66416 Regulation of Pnoc 1 66 0.61 17.32 68.91
129 INT7344 Gene_expression of TAC1 2 132 0.75 35.48 68.26
130 INT5861 Gene_expression of Egr1 2 203 0.78 49.35 68.13
131 INT462 Regulation of Pomc 1 157 0.62 41.67 67.27
132 INT1046 Gene_expression of LH 1 180 0.77 29.75 66.87
133 INT6824 Regulation of Gene_expression of Pdyn 1 114 0.62 9.48 66.73
134 INT6176 Positive_regulation of Htr1a 6 117 0.67 28.23 66.17
135 INT253 Regulation of PRL 8 184 0.62 47.27 65.79
136 INT24989 Positive_regulation of Cfp 3 125 0.61 29.55 64.9
137 INT5573 Negative_regulation of Gene_expression of Penk 2 113 0.59 21.83 64.66
138 INT5095 Localization of Ghrh 1 185 0.81 28.09 62.08
139 INT1169 Negative_regulation of Bche 1 322 0.59 149.22 61.27
140 INT1437 Negative_regulation of Pomc 4 132 0.59 35.22 60.97
141 INT2761 Regulation of Gabrg1 2 119 0.61 18.8 60.52
142 INT79093 Positive_regulation of Nos1 1 101 0.70 46.89 59.61
143 INT3161 Regulation of Localization of Gh 1 163 0.61 35.43 59.45
144 INT8732 Positive_regulation of Gene_expression of Oprm1 1 76 0.70 22.59 58.83
145 INT1307 Positive_regulation of Localization of Pomc 7 120 0.70 24.58 58.48
146 INT770 Regulation of Localization of Gnrhr 3 127 0.61 17.91 58.23
147 INT20964 Gene_expression of OPRK1 1 96 0.78 23.54 58.18
148 INT6669 Negative_regulation of Positive_regulation of Fos 1 98 0.59 23.5 56.82
149 INT1316 Positive_regulation of Acot1 2 129 0.60 18.86 56.13
150 INT1782 Regulation of Gh1 3 125 0.62 22 55.74
151 INT19 Regulation of Gnrhr 4 131 0.62 36.4 55.66
152 INT1579 Gene_expression of PRL 1 279 0.78 119.2 55.41
153 INT2421 Positive_regulation of Positive_regulation of Penk 2 97 0.69 13.38 55.32
154 INT4241 Regulation of CALCA 1 87 0.62 28.19 55.29
155 INT6826 Transcription of Pdyn 1 130 0.71 22.19 54.88
156 INT1486 Negative_regulation of Cpe 1 85 0.59 28.78 54.08
157 INT1456 Regulation of Oprl1 1 61 0.62 19.5 52.87
158 INT929 Positive_regulation of Oprl1 3 64 0.70 14.67 52.84
159 INT49017 Negative_regulation of Gene_expression of Nos2 3 169 0.59 80.64 52.67
160 INT6034 Binding of Gabrg1 2 115 0.47 17.48 51.92
161 INT22546 Positive_regulation of Gene_expression of Casp3 5 97 0.70 47.89 51.92
162 INT249 Localization of GHRH 3 215 0.80 78.02 51.87
163 INT1781 Negative_regulation of Gh1 2 127 0.59 16.94 51.77
164 INT5118 Regulation of SST 2 97 0.62 34.35 51.74
165 INT5136 Negative_regulation of PDYN 4 71 0.59 11.22 51.14
166 INT7287 Positive_regulation of Transcription of Penk 2 103 0.70 19.81 50.37
167 INT7059 Regulation of Adra2a 5 89 0.62 18.24 48.43
168 INT12471 Regulation of Insrr 1 52 0.35 17.8 48.31
169 INT1715 Positive_regulation of Nrm 1 51 0.70 24 47.53
170 INT30170 Gene_expression of Car2 1 330 0.66 77.26 46.76
171 INT20345 Gene_expression of Dbi 1 136 0.78 56.41 46.2
172 INT2783 Gene_expression of Slc3a1 3 86 0.65 8.84 45.4
173 INT49552 Negative_regulation of Positive_regulation of Casp3 3 76 0.55 36.04 44.78
174 INT27493 Negative_regulation of Casp3 9 114 0.56 56.89 44.63
175 INT5214 Localization of Cpe 1 49 0.73 13.3 44.36
176 INT989 Negative_regulation of Trh 1 90 0.59 15.45 43.63
177 INT1894 Negative_regulation of Localization of Gh 2 168 0.58 64.12 43.56
178 INT935 Localization of Gtf3a 1 124 0.70 35.72 43.3
179 INT1319 Gene_expression of Oprl1 2 65 0.78 9.34 42.41
180 INT9039 Negative_regulation of Htr1a 4 69 0.57 9.56 41.84
181 INT957 Positive_regulation of GHRH 4 136 0.70 36.84 40.52
182 INT7029 Regulation of Pdyn 3 51 0.61 12.89 40.34
183 INT92437 Positive_regulation of Phosphorylation of Mapk1 4 113 0.70 32.19 40.29
184 INT114751 Gene_expression of Mapk1 1 137 0.76 60.14 39.98
185 INT7824 Regulation of Cck 1 39 0.62 5.31 39.28
186 INT1596 Negative_regulation of Oprl1 1 61 0.57 13.5 38.41
187 INT916 Regulation of Localization of PRL 2 92 0.62 22.98 38.13
188 INT77307 Gene_expression of Bcl2 1 399 0.77 319.77 38
189 INT88081 Negative_regulation of Gene_expression of Oprm1 1 45 0.59 16.56 37.5
190 INT11246 Binding of Grin1 1 65 0.48 14.53 36.93
191 INT6067 Positive_regulation of Positive_regulation of Oprd1 1 37 0.69 6.56 36.58
192 INT2416 Negative_regulation of MAOA 1 92 0.59 42.24 36.5
193 INT1354 Negative_regulation of Acot1 1 87 0.43 15.01 36.44
194 INT1976 Regulation of Gene_expression of Prl 1 80 0.62 20.19 36
195 INT316 Regulation of Cebpz 1 105 0.00 27.21 35.41
196 INT255 Regulation of Localization of GH1 1 89 0.62 18.71 35.3
197 INT10796 Gene_expression of CYP2B6 1 131 0.77 30.14 35.27
198 INT7608 Positive_regulation of Adra2a 3 66 0.70 17.81 35.15
199 INT326 Gene_expression of Gnrhr 1 105 0.76 35.87 34.93
200 INT692 Negative_regulation of SST 1 72 0.59 28.68 34.52
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